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Relevant bibliographies by topics / Surveillance immune / Dissertations / Theses

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Dissertations / Theses on the topic 'Surveillance immune'

Author: Grafiati

Published: 25 May 2024

Last updated: 31 July 2025

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1

Rosenthal, Rachel Suzanne. "Immune editing and surveillance in cancer evolution." Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/10047362/.

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Cancer is an evolutionary disease, reliant on genetic diversity and sculpted by selective forces from the immune microenvironment. Here, I use genomics data to decipher the tumor’s evolutionary trajectory and corresponding shifts in the immune contexture to elucidate the events governing tumor immunogenicity and the immune evasive mechanisms evolved by the tumor. To better understand the mutational processes contributing to intratumor heterogeneity in individual tumors, a method to quantify the activity of mutational processes in a single tumor sample was developed and applied to temporally di

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2

SCHEIDECKER, CATHERINE. "Cellule nk : surveillance immune et resistance naturelle." Strasbourg 1, 1987. http://www.theses.fr/1987STR10724.

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Marri, Eswari. "Immune surveillance of activated immune and tumour cells by surfactant protein D." Thesis, Brunel University, 2015. http://bura.brunel.ac.uk/handle/2438/13847.

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Surfactant protein D (SP-D) is a carbohydrate/charged pattern recognition molecule of the innate immune system. By virtue of its ability to recognize an array of carbohydrate patterns on the surface of a range of pathogens, SP-D can bring about opsonisation, enhanced phagocytosis and killing of a diverse range of viruses, bacteria and fungi. In addition to antimicrobial functions, which also includes bacteriostatic and fungistatic properties SP-D has also been shown to bind allergens derived from a number of sources including house dust mite, Aspergilllus fumigatus and pollen grains. SP-D alle

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4

Kaur, Anuvinder. "Innate immune surveillance in ovarian and pancreatic cancer." Thesis, Brunel University, 2017. http://bura.brunel.ac.uk/handle/2438/15847.

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Activation of innate immune surveillance mechanisms during the development of cancer is well-documented. However, knowledge of how these innate immune proteins, when added exogenously, independent of tumour microenvironment, affect tumour cells is limited. In Chapter 3, the effects of human C1q and its individual globular domains (ghA, ghB and ghC) on an ovarian cancer cell line, SKOV3, have been examined. C1q and globular head modules induced apoptosis in approximately 55% of cells, which involved upregulation of TNF-α and Fas and activation of the caspase cascade. This occurred in parallel t

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5

Cheung, Ann F. "Investigating immune surveillance, tolerance, and therapy in cancer." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/46809.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2009.<br>This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.<br>Vita.<br>Includes bibliographical references.<br>Maximizing the potential of cancer immunotherapy requires model systems that closely recapitulate human disease to study T cell responses to tumor antigens and to test immune therapeutic strategies. Current model systems largely relied on chemically-induced and spontaneous tumors in immunodeficient mice or on transpl

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Loughhead, Scott McNabb. "Immune Surveillance by Effector and Memory CD8+ T Cells." Thesis, Harvard University, 2016. http://nrs.harvard.edu/urn-3:HUL.InstRepos:26718721.

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During priming, CD8+ T cells integrate a plethora of signals that affect their differentiation into subsets of CD8+ T cells with distinct migratory properties and functions. Given that CD8+ T cells exert their protective function via cell-cell contacts, the migratory patterns and spatial distribution of CD8+ T cell subsets induced by primary challenge are of critical importance to the host. Dendritic cells (DCs), as the primary initiators of these responses, play a pivotal role in shaping the size and differentiation status of CD8+ T cells that emerge. However, inadequate markers for CD8+ T ce

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7

Sowinski, Stefanie. "Transmission and immune surveillance of human T cell-tropic retroviridae." Thesis, Imperial College London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501764.

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8

Textor, Johannes [Verfasser]. "Search and learning in the immune system : models of immune surveillance and negative selection / Johannes Textor." Lübeck : Zentrale Hochschulbibliothek Lübeck, 2012. http://d-nb.info/1024336921/34.

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Blaimer, Stephanie [Verfasser], and Edward K. [Akademischer Betreuer] Geissler. "Impact of innate and adaptive immune cells in tumor immune surveillance / Stephanie Blaimer ; Betreuer: Edward K. Geissler." Regensburg : Universitätsbibliothek Regensburg, 2020. http://d-nb.info/1210729202/34.

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10

Strickland, Ian. "The role of immune surveillance in inflammatory reactions in human skin." Thesis, University of Liverpool, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.307670.

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11

Joyce, Stephen Paul. "Exploring the role of Vδ1+ γδ T cells in immune stress surveillance". Thesis, University of Birmingham, 2015. http://etheses.bham.ac.uk//id/eprint/5904/.

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γδ T cells play a central role in the detection of epithelial stress as a component of the lymphoid stress surveillance response. Despite their implication in a range of conditions, including several cancers, little is known about how they interact with their antigenic targets, particularly the interaction of γδ TCRs with their ligands. In this thesis I used molecular and structural modelling techniques to characterise recognition of an epithelial stress ligand, EphA2, by a Vδ1+ γδ T cell, MAU. This resulted in a tripartite model of recognition, involving coordinated interaction of EphA2 with

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12

Taner, Sabrina Beliz. "The role of lipid rafts in natural killer cell activation and immune surveillance." Thesis, Imperial College London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.423546.

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13

CASU, BEATRICE. "Analysis of novel tumor escape mechanisms from the Natural killer (NK) cells-mediated immune-surveillance." Doctoral thesis, Università degli studi di Genova, 2019. http://hdl.handle.net/11567/945499.

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14

Marchiori, Chiara. "The role of immune surveillance mechanisms acting to prevent an AOM - induced colorectal carcinogenesis progression." Doctoral thesis, Università degli studi di Padova, 2018. http://hdl.handle.net/11577/3425881.

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Colorectal cancer (CRC) is one of the most frequent cancer worldwide both in men and women. This tumour is the result of a multistep process in which there is a closed connection between the tumour development and immune system is the so-called immune surveillance, a dynamic process that comprises three different steps: elimination, equilibrium and escape. The hypothesis of my PhD project was that CD80 expression on dysplastic epithelial cells is crucial also in successful immune surveillance of sporadic colorectal cancer. The analysis of human colonic surgical specimens demonstrated that CD80

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15

GILIOLI, DIEGO. "Dissecting the role of cellular senescence in acute myeloid leukaemia immune-surveillance and response to therapy." Doctoral thesis, Università Vita-Salute San Raffaele, 2022. http://hdl.handle.net/20.500.11768/133076.

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Pieper, Natalia [Verfasser], та Annette [Akademischer Betreuer] Paschen. "Impact of IFN-γ resistance & MAPK inhibition on the immune surveillance of malignant melanoma - relevance for immune-based therapies / Natalia Pieper ; Betreuer: Annette Paschen". Duisburg, 2019. http://d-nb.info/1201274095/34.

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17

Wischhusen, Jörg. "Resistance to apoptosis and escape from host immune surveillance two related (?) survival mechanisms of malignant glioma cells /." [S.l. : s.n.], 2004. http://www.bsz-bw.de/cgi-bin/xvms.cgi?SWB11482185.

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18

Nougue, Manon. "Rôle immunomodulateur du système lymphatique lors du développement tumoral mammaire." Electronic Thesis or Diss., Toulouse 3, 2023. http://www.theses.fr/2023TOU30261.

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Le système lymphatique est un réseau vasculaire unidirectionnel transportant la lymphe qui permet le drainage des fluides interstitiels, le transport des lipides intestinaux, ainsi que la surveillance et la tolérance immunitaire. Néanmoins, le système lymphatique est impliqué dans de nombreuses pathologies et particulièrement dans la progression tumorale. En effet, le système lymphatique favorise la dissémination des métastases qui sont acheminées par les vaisseaux lymphatiques jusqu'aux organes distants. Plus récemment, le système lymphatique a été identifié comme un régulateur clé des répons

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Hudspeth, K. L. "THE ROLE OF NATURAL CYTOTOXICITY RECEPTORS IN THE HOMEOSTASIS AND FUNCTION OF A NEWLY DISCOVERED SUBSET OF HUMAN GAMMA DELTA T CELLS." Doctoral thesis, Università degli Studi di Milano, 2013. http://hdl.handle.net/2434/218988.

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Natural Cytotoxicity Receptors (NCRs) were originally identified as specific natural killer cell activating receptors that, upon binding to their endogenous ligands, trigger the killing of tumor cell targets. Here we describe a population of Vδ1 + T cells from human peripheral blood that can differentiate in vitro to express the NCRs NKp30, NKp44 and NKp46. Moreover, we show that the expression of NKp30 endows Vδ1 + T cells with the ability to suppress HIV-1 viral replication and lyse hematologic tumor cells in vitro, through the production of CC chemokines and cytolytic granules, respectivel

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Enzler, Thomas. "GM-CSF and IFN-[gamma] [IFN-gamma] deficiency link autoimmune diseases and cancer a cancer immune surveillance controversy /." [S.l.] : [s.n.], 2004. http://www.diss.fu-berlin.de/2004/153/index.html.

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21

Du, Page Michel Justin Porter. "Investigation of T cell-mediated immune surveillance against tumor-specific antigens in genetically engineered mouse models of cancer." Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/62620.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2011.<br>This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.<br>Cataloged from student-submitted PDF version of thesis. Vita.<br>Includes bibliographical references.<br>The association of tumor cells and lymphocytes has led to the hypothesis that our immune system actively inhibits the formation and progression of cancer, a phenomenon called tumor immune surveillance. T cells specific to mutant proteins have been identified in

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22

Joshi, Urjita [Verfasser], and Bernd [Akademischer Betreuer] Engelmann. "Role of extracellular vesicles, microvascular fibrin formation and immune surveillance in pancreatic cancer metastasis / Urjita Joshi ; Betreuer: Bernd Engelmann." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2018. http://d-nb.info/1191097951/34.

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DI, CAMILLO FEDERICA. "Analisi degli effetti del miR-30d sulla via di segnalazione immune cGAS/STING/IFN-I in cellule di carcinoma mammario." Doctoral thesis, Università degli Studi di Trieste, 2023. https://hdl.handle.net/11368/3042422.

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I tumori sono ecosistemi complessi, nei quali popolazioni eterogenee di cellule tumorali sono immerse in un microambiente dinamico. La comunicazione delle cellule tumorali con il microambiente causa effetti protumorigenici sia locali che sistemici, tra cui l’angiogenesi, il rimodellamento della matrice extracellulare, e la modulazione della componente immunitaria/infiammatoria, supportando la progressione tumorale e l’evasione dalla sorveglianza immunitaria. La comprensione dei meccanismi di evasione dal sistema immunitario è di particolare importanza per migliorare l'efficacia delle immunoter

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Gonçalves, Maia Maria João. "Le syndrome Xeroderma Pigmentosum : Un nouveau modèle pour l’étude du rôle des fibroblastes dans la modulation de la réponse immunitaire innée contre les cellules cutanées cancéreuses." Electronic Thesis or Diss., Université Côte d'Azur (ComUE), 2019. http://www.theses.fr/2019AZUR4037.

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L’étiologie des cancers cutanées est liée à des mutations génétiques résultant de l’exposition aux rayonnements ultraviolets (UV) émis par le soleil. La propagation des cellules cancéreuses dépend aussi des interactions avec les cellules présentes dans le microenvironnement circulant, notamment des fibroblastes associés au cancer (FAC) et des cellules immunitaires. Xeroderma pigmentosum (XP) est une maladie génétique qui comprend 7 groupes de complémentation génétique (XP-A à XP-G). Les patients XP présentent une déficience du mécanisme de réparation des lésions de l’ADN provoquées par les UV.

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25

Pereira, Abrantes Manuela. "Hétérogénéité des neutrophiles et leurs écosystèmes dans l’immunosurveillance au cours de la tumorigenèse." Electronic Thesis or Diss., Lyon 1, 2023. http://www.theses.fr/2023LYO10147.

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Le neutrophile est la cellule immunitaire la plus représentée dans le sang chez l’Homme, dont la migration au site inflammatoire est rapide. Le rôle du neutrophile a largement été décrit dans des contextes infectieux, auto-immunitaires et allergiques mais reste controversé dans le cancer, notamment dans les mécanismes d’immunosurveillance précoce. Le neutrophile se révèle être une population hétérogène tant phénotypiquement que fonctionnellement. L’origine et la compréhension de l’hétérogénéité des neutrophiles est un sujet émergent et croissant, mais aucune étude à ce jour ne décrit l’évoluti

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Marchand, Adrien. "Pertinence écologique des biomarqueurs d'immunotoxicité en surveillance environnementale . Evaluation of chlorpyrifos effects, alone and combined with lipopolysaccharide stress, on DNA integrity and immune responses of three-spined stickleback, Gasterosteus aculeatus." Thesis, Reims, 2018. http://www.theses.fr/2018REIMS049.

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Ce travail propose d’améliorer les connaissances sur la variabilité naturelle des immunomarqueurs cellulaires innées chez un poisson modèle en écotoxicologie, l’épinoche à trois-épines, Gasterosteus aculeatus. Il a pour but la détermination de valeurs de référence utilisables dans un contexte de biosurveillance passive pour chacun des immunomarqueurs considérés. Ainsi, l’effet de trois facteurs confondants, que sont la période de prélèvement, la taille et le sexe des organismes, a été étudié en conditions contrôlées de laboratoire. Il a été ainsi possible d’obtenir, pour chaque immunomarqueur,

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Perroud, Junior Mauricio Wesley 1971. "Avaliação de viabilidade, tolerância e segurança da vacina com células dendríticas autológas maduras em pacientes com carcinoma de pulmão não pequenas células avançado = Assessment of feasibility, safety and tolerance of mature autologous dendritic cells vaccine in patients with advanced non-small cell lung carcinoma." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310256.

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Orientador: Lair Zambon<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-21T10:28:19Z (GMT). No. of bitstreams: 1 PerroudJunior_MauricioWesley_D.pdf: 9913138 bytes, checksum: 5dd1ec64b004b6d50e2392e6383c9c98 (MD5) Previous issue date: 2012<br>Resumo: Os resultados terapêuticos globais do carcinoma de pulmão não pequenas células em estádio avançado são bem limitados. A imunoterapia com células dendríticas foi desenvolvida como uma nova estratégia para o tratamento de câncer de pulmão. O objetivo deste estudo foi aval

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Rorat, Agnieszka. "Assessment of the vermicomposting process applied to sewage sludge by monitoring of the compost quality and immune responses of three earthworm species : Eisenia fetida, Eisenia andrei and Dendrobaena veneta." Thesis, Lille 1, 2015. http://www.theses.fr/2015LIL10165.

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Le vermicompostage est une éco-biotechnologie relativement nouvelle qui utilise des vers de terre comme bioréacteurs naturels dans un procéssus de décomposition de la matière organique. En Europe, on utilise trois espèces d’annélides oligochètes : Eisenia fetida, Eisenia andrei et Dendrobaena veneta. Compte tenu des directives de l’Union Européenne portant sur le traitement des déchets, les contenus en métaux lourds, en composés chimiques divers et en microorganismes pathogènes des boues d’épuration ne permettent pas leur valorisation directe en agriculture. La qualité du produit obtenu après

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Levy, Jonathan. "Étude du rôle de l’autophagie dans la cancérogenèse intestinale." Thesis, Paris 11, 2014. http://www.theses.fr/2014PA11T049/document.

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Considéré comme un cancer de l'âge mûr, l'incidence du cancer colorectal ne cesse d'augmenter avec l'allongement de la vie. Dans la majorité des cas, le cancer colique est associé à une mutation du gène suppresseur de tumeur Apc, contrôlant l’activation de la signalisation Wnt/β-caténine. Afin, d'identifier de nouveaux acteurs de la tumorigenèse colique, notre laboratoire a développé des modèles murins de mutation du gène Apc qui ont pour avantage de mimer la pathologie humaine (Colnot et al, 2004 ; Andreu et al, 2005). La création de ces modèles a permis à l’équipe de démontrer i) qu’une acti

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Pérez, lanzón María. "Modeling Hormone Receptor Positive Breast Cancer in Immunocompetent Mice Blocking tumor-educated MSC paracrine activity halts osteosarcoma progression Organoids for Modeling Genetic Diseases. In: International Review of Cell and Molecular Biology A preclinical mouse model of osteosarcoma to define the extracellular vesicle-mediated communication between tumor and mesenchymal stem cells Failure of immunosurveillance accelerates aging The metabolomic signature of extreme longevity: Naked mole rats versus mice Lurbinectedin synergizes with immune checkpoint blockade to generate anticancer immunity Laminin-binding integrins are essential for the maintenance of functional mammary secretory epithelium in lactation Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer." Thesis, université Paris-Saclay, 2021. http://www.theses.fr/2021UPASL019.

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Les progrès de la recherche sur le cancer du sein dépendent de la disponibilité d’outils appropriés, comme les lignées cellulaires qui peuvent être implantées chez des souris immunocompétentes. La souche de souris C57Bl/6 est la plus étudiée et c’est la seule pour laquelle certaines variantes génétiques sont disponibles. Étant donné qu'aucune lignée cellulaire de carcinome mammaire à récepteurs hormonaux positifs de souche C57Bl/6 n'est disponible, nous avons décidé d'établir des lignées cellulaires de ce type. Nous avons induit des cancers du sein chez des souris C57BL/6 femelles en utilisant

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Azour, Halima. "Etude et réalisation d'un nouveau concept de dépistage rapide d'anticorps anti-érythrocytaires et élaboration d'un nouveau mode de titrage d'anticorps anti-érythrocytaires utilisables dans la surveillance des immunisations fœto-maternelles." Bordeaux 2, 1997. http://www.theses.fr/1997BOR28551.

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Pittari, Gianfranco. "NK Cell Tolerance of Self-Specific Apecific Activating Receptor KIR2DS1 in Individuals with Cognate HLA-C2 Ligand." Thesis, Paris 11, 2013. http://www.theses.fr/2013PA11T043.

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Les cellules tueuses naturelles (NK) sont régulées par des récepteurs activateurs et inhibiteurs. La plupart des récepteurs inhibiteurs reconnaisse des molécules du complexe majeur d'histocompatibilité (CMH) de classe I, et protège les cellules saines des phénomènes d'auto-immunité médiés par les cellules NK. Cependant, certains récepteurs activateurs, incluant le récepteur killer cell Ig-like receptor (KIR) 2DS1, reconnaissent aussi des ligands CMH de classe I. Cela pose la question de savoir comment les cellules NK qui expriment des récepteurs activateurs deviennent tolérantes au soi. Nous a

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Aarab-Terrisse, Safae. "Impact de l'axe microbiome-thymus sur l'efficacité de la déprivation androgénique et sur le renforcement de l’immuno-surveillance dans le cancer de la prostate Immunodynamics of Explanted Human Tumors for Precision and Personalized Immuno-Oncology Gut Bacteria Composition Drives Primary Resistance to Cancer Immunotherapy in Renal Cell Carcinoma Patients." Thesis, université Paris-Saclay, 2020. http://www.theses.fr/2020UPASL025.

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La déprivation androgénique est la pierre angulaire du traitement du cancer de la prostate (CaP), mais la plupart des patients deviendront réfractaires à la castration (CRPC). En outre, les immunothérapies par inhibiteurs de points de contrôle immunitaire ne sont pour l’instant pas un standard dans la prise en charge de ce cancer en raison de son environnement immunosuppresseur. Notre hypothèse est que pour accroître la sensibilité des patients aux traitements immuno-modulateurs (déprivation androgénique, inhibiteurs des points de contrôle immunitaire et autres), il faudrait restaurer l’enviro

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Chen, Yung Che, and 陳永哲. "Investigating the role of epigenetic change-mediated compromised immune surveillance in lung disease." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/24945375796033288877.

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博士<br>長庚大學<br>臨床醫學研究所<br>103<br>The purpose of this thesis research is to investigate epigenetic changes-mediated compromised immune surveillance that may affect the development of two common lung diseases, pulmonary tuberculosis (TB) and lung cancer. Both diseases develop when the individual’s immune system can not execute its normal function to eradicate either M.tb or tumor cell. Epigenetic changes, such as DNA methylation, play an essential role in regulating immune responses and gene expressions to environmental stimuli, such as hypoxia, toxin, and infection. Thus, we sough to identify ep

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Cunningham, Thomas D. "Estrogen inducible Proteinase Inhibitor 9 protects target cells from immune surveillance and apoptosis /." 2008. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3337746.

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Thesis (Ph. D.)--University of Illinois at Urbana-Champaign, 2008.<br>Source: Dissertation Abstracts International, Volume: 69-11, Section: B, page: 6768. Adviser: David J. Shapiro. Includes bibliographical references. Available on microfilm from Pro Quest Information and Learning.

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Witalis, Mariko. "Immune mechanisms controlling angioimmunoblastic T cell lymphoma progression." Thesis, 2020. http://hdl.handle.net/1866/25274.

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Le lymphome angioimmunoblastique à cellules T (AITL) est un lymphome périphérique à cellules T agressif dont les symptômes sont la lymphadénopathie et l'hypergammaglobulinémie. Actuellement, les patients atteints du AITL ont des options de thérapeutiques limitées et des résultats cliniques défavorables, avec un taux de survie sur 5 ans d'environ 30%. Les cellules tumorales du AITL proviennent de cellules T CD4+ appelées cellules T auxiliaires folliculaires (Tfh). Les cellules Tfh sont essentielles dans le centre germinatif (GC), où elles facilitent l'expansion et la différentiation des cellule

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Baschuk, Nikola [Verfasser]. "Immune surveillance of cancer : molecular and translational aspects of cytotoxic effector : target cell interactions / vorgelegt von Nikola Baschuk." 2009. http://d-nb.info/998592005/34.

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CHEN, LI-TING, and 陳立亭. "To Investigate the Effect of T cell Specific Transgenic Blimp-1 Expression on Immune Surveillance of Glioma-Bearing Mice." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/dd2hs4.

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碩士<br>國防醫學院<br>微生物及免疫學研究所<br>104<br>Glioblastoma multiforme (GBM) is kind of glioma, it’s also the most common primary central nervous system malignant tumor. Standard treatment includes surgical resection, chemo-therapy combine radiation therapy. However, previous research indicated that GBM grow fast and is highly invasive. Despite standard treatment, the median survival of GBM patients is less than 16 months. For these reasons, the present study focuses on gene therapy and immunotherapy for GBM. Immune system plays an important role on eliminating abnormal cells (e.g., over-proliferated cel

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Enzler, Thomas [Verfasser]. "GM-CSF and IFN-γ [IFN-gamma] deficiency link autoimmune diseases and cancer : a cancer immune surveillance controversy / of Thomas Enzler". 2004. http://d-nb.info/971611033/34.

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Aulwurm, Steffen Alexander [Verfasser]. "Aktivierung der angeborenen und adaptiven Immunantwort und deren Bedeutung bei der Immunantwort gegenüber malignen Gliomen = Activation of the innate and adaptive immune response and its role in the immune surveillance of malignant glioma / vorgelegt von Steffen Alexander Aulwurm." 2005. http://d-nb.info/974850012/34.

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Wischhusen, Jörg Hinrich [Verfasser]. "Apoptoseresistenz und Vermeidung von Anti-Tumor-Immunität -zwei verwandte (?) Überlebensstrategien maligner Gliomzellen = Resistance to apoptosis and escape from host immune surveillance - two related (?) survival mechanisms of malignant glioma cells / vorgelegt von Jörg Hinrich Wischhusen." 2004. http://d-nb.info/972522425/34.

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Chang, Chun-Jung, та 張峻榮. "Evasion of fibrotic lung myofibroblasts from IFN-γ immuno-surveillance". Thesis, 2019. http://ndltd.ncl.edu.tw/handle/7ygg7j.

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Dessureault, Mireille. "Effet du sécrétome des cellules sénescentes sur la réponse inflammatoire orchestrée par les macrophages." Thèse, 2016. http://hdl.handle.net/1866/18640.

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L’élimination des cellules sénescentes met en jeu le SASP et les cellules immunitaires de l’immunité innée et adaptative tels que les macrophages (Mφ). Dans le cadre de ce projet, nous rapportons que le SASP a un effet pléiotropique sur l’activité des cellules immunitaires incluant leur recrutement, leur activation et leur différenciation. Nos données montrent que les Mφ humains mis en culture avec le SASP de fibroblastes humains développement un profil inflammatoire spécifique au SASP caractérisé par une sécrétion pro-inflammatoire (M1) (ex : IL- 1β, GM-CSF) et des marqueurs de surface anti-i

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