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Academic literature on the topic 'Supraspinatus tendon'

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Published: 4 June 2021
Last updated: 8 February 2022

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Journal articles on the topic "Supraspinatus tendon"

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Andarawis-Puri, Nelly, Eric T. Ricchetti, and Louis J. Soslowsky. "Interaction between the Supraspinatus and Infraspinatus Tendons: Effect of Anterior Supraspinatus Tendon Full-Thickness Tears on Infraspinatus Tendon Strain." American Journal of Sports Medicine 37, no. 9 (May 29, 2009): 1831–39. http://dx.doi.org/10.1177/0363546509334222.

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Background Rotator cuff tears are common and not well-understood shoulder problems. Structural and mechanical inhomogeneity of the supraspinatus tendon complicates accurate prediction of risk of tear propagation and may affect appropriate clinical treatment. Hypothesis We propose that interactions between the supraspinatus and infraspinatus tendons are critical to load bearing at the glenohumeral joint and warrant investigation. Study Design Controlled laboratory study. Methods Principal strains in the infraspinatus tendon of cadaveric human shoulders were evaluated with increasing anterior full-thickness supraspinatus tendon tear sizes and loading to evaluate whether a mechanical interaction between the supraspinatus and infraspinatus tendons exists. A constant nominal load was attached to the infraspinatus throughout all experimental conditions. Results Increasing supraspinatus tendon tear width from intact and 33% to 66% and increasing supraspinatus tendon load caused an increase in maximum and a decrease in minimum principal strain in the infraspinatus tendon. Increasing the supraspinatus tendon tear size from intact to 33% of the width had no significant effect on infraspinatus tendon strain. Conclusion Supraspinatus and infraspinatus tendons mechanically interact. The observed significant increase in maximum and decrease in minimum principal strain was concurrent in both the infraspinatus and supraspinatus tendons. Clinical Relevance Changes in infraspinatus tendon strain associated with increases in supraspinatus tendon tear size and loading may shield a torn supraspinatus tendon from further injury or may have an effect on the load-bearing capacity of the infraspinatus tendon. Results also imply that the effect of a small tear that does not compromise the confluent region between the supraspinatus and infraspinatus tendon may be localized, eliminating its effect on infraspinatus tendon strain.
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Hackett, Lisa, Ricardo Aveledo, Patrick H. Lam, and George AC Murrell. "Reliability of shear wave elastography ultrasound to assess the supraspinatus tendon: An intra and inter-rater in vivo study." Shoulder & Elbow 12, no. 1 (January 12, 2019): 18–23. http://dx.doi.org/10.1177/1758573218819828.

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Introduction Shear wave elastography ultrasound is a relatively new technique that evaluates the tissue elasticity by applying an acoustic radiation force impulse. It is undetermined how reliable this modality is in assessing rotator cuff tendons. The aim of this study, therefore, was to evaluate the reliability of shear wave elastography ultrasound to assess the stiffness of normal and tendinopathic supraspinatus tendons. Methods An inter- and intra-rater reliability trial was carried out using shear wave elastography to assess the supraspinatus tendon at its distal insertion, by measuring shear wave velocity and elasticity. Twenty participants with a mean age of 37 (21–69) years old were evaluated. Ten subjects with normal supraspinatus tendon and 10 subjects with tendinopathic tendon were selected. The Virtual Touch Imaging Quantification program was used to generate the acoustic radiation force impulse and to obtain the elastography data. Three raters with different experience in conventional ultrasound were used for the inter-rater trial in normal tendons and the most experienced rater examined all subjects for the intra-rater reliability evaluation. Each rater obtained three readings in three different examinations per subject over a one-week period. Results The mean (±SEM) shear wave velocity for the normal supraspinatus tendon was 9.96 ± 0.02 m/s (=297 kPa), while in the tendinopathic supraspinatus tendon was 8.3 ± 0.2 m/s (=207 kPa) (p < 0.001). The intra-rater trial agreement was excellent, with an intraclass correlation coefficient = 0.96. In the inter-rater testing, the mean shear wave velocity in normal tendons was 9.90 ± 0.07 m/s (=294 kPa), with intraclass correlation coefficient = 0.45. Conclusion Shear wave elastography ultrasound was able to show that tendinopathic tendons were less stiff than normal tendons. It was a reliable imaging technique to assess the supraspinatus tendon, especially when used by a single experienced musculoskeletal sonographer.
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Mistieri, Maria Ligia A., Antje Wigger, Julio C. Canola, João G. P. Filho, and Martin Kramer. "Ultrasonographic Evaluation of Canine Supraspinatus Calcifying Tendinosis." Journal of the American Animal Hospital Association 48, no. 6 (November 1, 2012): 405–10. http://dx.doi.org/10.5326/jaaha-ms-5818.

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Supraspinatus calcifying tendinosis is an uncommon finding in dogs. Although its radiographic appearance has been described previously, radiographs alone do not provide detailed information about the tendon parenchyma. Tendon ultrasonography has been widely applied for the diagnosis of human tendinosis, but it remains underused in dogs. This article reviews the ultrasonographic technique and variable appearance of canine supraspinatus calcifying tendinosis observed in 33 tendons. The ultrasonographic findings are described. The most common ultrasonographic finding was a hyperechoic area accompanied by distal acoustic shadowing. No relationship with bicipital tenosynovitis was found. A color Doppler examination was possible in only five of the tendons, revealing no blood flow in those tendons. There was evidence that the presence of a hypoechoic area surrounding the calcification was related to clinical signs of pain, suggesting an active inflammatory process. Ultrasonography was an excellent technique to evaluate lesions of the supraspinatus tendon and it revealed details not apparent on radiographs.
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Thompson, Simon M., Joe A. I. Prinold, Adam M. Hill, Peter Reilly, Roger J. H. Emery, and Anthony M. J. Bull. "The influence of full-thickness supraspinatus tears on abduction moments: the importance of the central tendon." Shoulder & Elbow 11, no. 1_suppl (July 10, 2017): 19–25. http://dx.doi.org/10.1177/1758573217717104.

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Background Detachment of the central tendon of the supraspinatus from its insertion is considered to be crucial to functional deficit. The aim of the present study was to assess the function of the supraspinatus in terms of abduction moments by introducing different tear configurations to assess the functional effect of the central tendon insertion. Methods Ten fresh frozen shoulders from five cadavers were prepared for testing. A testing protocol was established to measure the abduction moment of the supraspinatus under physiological loading tailored to the anthropometrics of each specimen. Four conditions were tested: intact supraspinatus; complete detachment of portion of the supraspinatus tendon anterior to the main central tendon; detachment of the main central tendon; and detachment of the region of the supraspinatus posterior to the main central tendon. Results There was a significant and large reduction in abduction moment when the central tendon was sectioned ( p < 0.05). A smaller reduction in abduction moment was found when the regions anterior and posterior to the main central tendon were sectioned ( p < 0.05). Conclusions The central tendon is vital in the role of functional arm abduction through force transmission through the intact rotator cuff. Reinsertion of the central tendon in the correct anatomical location is desirable to optimize functional outcome of surgery.
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Kriegleder, H. "Mineralization of the Supraspinatus Tendon: Clinical Observations in Seven Dogs." Veterinary and Comparative Orthopaedics and Traumatology 08, no. 02 (1995): 91–97. http://dx.doi.org/10.1055/s-0038-1632435.

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SummaryMineral-like densities in the supraspinatus tendon were determined to have different clinical significance according to their location. Those identified radiographically and surgically, near the biceps tendon sheath reflecting a deep location in the supraspinatus tendon, caused chronic and acute lameness in five large breed dogs. Pain in the shoulder and biceps tendon was elicited on examination in acute cases whilst chronic cases were painfree. Systemic and local anti-inflammatory treatment failed to improve any of the cases. Surgical removal was curative with slight lameness after exercise observed in some dogs during the longterm follow-up. Recurrence of lesions were not seen radiologically. It is suggested that mineralizations, located deep in the supraspinatus tendon, cause secondary tenosynovitis of the biceps brachii through mechanical irritation.Mineralizations found radiographically distant to the biceps tendon sheath in five cases reflecting a superficial location in the supraspinatus were determined not to be a primary cause of lameness.Similarities in the pathomechanism, aetiopathogenesis and clinical significance of mineralizations in the supraspinatus tendon in dogs and humans were noted.Mineralizations located deep in the supraspinatus tendon near the biceps tendon sheath caused lameness in large breed dogs. Diagnosis was established through physical examination, radiography, and surgical exploration of the lesion. Systemic steroidal and non-steroidal therapy and local steroid injection into the intertubercular groove failed to resolve any of the cases but surgical curettage of the mineralization resulted in clinical improvement. A secondary mechanical tenosynovitis of the biceps brachii as the cause of lameness, is suggested.Mineralizations located superficially in the supraspinatus tendon were found not to be a primary cause of lameness.
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Brage, Karen, Birgit Juul-Kristensen, John Hjarbaek, Eleanor Boyle, Per Kjaer, and Kim Gordon Ingwersen. "Strain Elastography and Tendon Response to an Exercise Program in Patients With Supraspinatus Tendinopathy: An Exploratory Study." Orthopaedic Journal of Sports Medicine 8, no. 12 (December 1, 2020): 232596712096518. http://dx.doi.org/10.1177/2325967120965185.

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Background: Shoulder pain is common, with a lifetime prevalence of up to 67%. Evidence is conflicting in relation to imaging findings and pain in the shoulder. Sonoelastography can be used to estimate tissue stiffness and may be a clinically relevant technique for diagnosing and monitoring tendon healing. Purpose: To evaluate changes in supraspinatus tendon stiffness using strain elastography (SEL) and associations with changes in patient-reported outcomes, supraspinatus tendon thickness, and grade of tendinopathy after 12 weeks of unilateral shoulder exercises in patients with supraspinatus tendinopathy. Study Design: Controlled laboratory study. Methods: A total of 23 patients with unilateral clinical supraspinatus tendinopathy performed 12 weeks of “standard care” exercises. At baseline and follow-up, supraspinatus tendon stiffness was measured bilaterally using SEL and compared with tendinopathy grading on magnetic resonance imaging scans and tendon thickness measured using conventional ultrasound. Patient-reported outcome measures included physical function and symptoms from the Disabilities of the Arm, Shoulder and Hand questionnaire and pain rating (visual analog scale). Results: No significant changes in SEL within or between groups (asymptomatic vs symptomatic tendon) were seen. All patient-reported outcomes showed significant improvement from baseline to follow-up, but with no change in tendinopathy grading and tendon thickness. No significant differences in the proportion of patients changing above the minimal detectable change in SEL and PROM were seen, except for discomfort while sleeping. Conclusion: Despite no significant within-group or between-group changes in SEL, significant improvements were found in patient-reported outcomes. An acceptable agreement between patients changing above the minimal detectable change in SEL and patient-reported outcome measure was seen. Further studies should explore the use of SEL to detect changes after tendon repair and long-term training potentially in subgroups of different tendinopathy phases. Clinical Relevance: In the short term, structural changes in supraspinatus tendons could not be visualized using SEL, indicating that a longer time span should be expected in order to observe structural changes, which should be considered before return to sports. Subgrouping based on stage of tendinopathy may also be important in order to evaluate changes over time with SEL among patients with supraspinatus tendinopathy. Registration: NCT03425357 ( ClinicalTrials.gov identifier).
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Strafun, S. S., S. V. Bohdan, and S. M. Abbasov. "Bone Densitometry Indices of Humerus Bone in Patients with Partial Rupture of the Supraspinatus Tendon." Visnyk Ortopedii Travmatologii Protezuvannia, no. 1(104) (June 30, 2020): 71–77. http://dx.doi.org/10.37647/0132-2486-2020-104-1-71-77.

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Summary. Bone density is an important factor that affects the strength of the suture of the tendons of the rotator cuff. The higher the bone density is, the greater is the strength of fixation of the supraspinatus tendon to the bone, since the anchor is more securely fixed in the bone. Objective: to determine the bone mineral density of the proximal humeral epiphysis in patients with partial tear of the supraspinatus tendon. Materials and Methods. An X-ray examination of 48 shoulder joints (24 with partial tear of the supraspinatus tendon and 24 intact contralateral) was performed in 24 patients with partial tear of the supraspinatus tendon. On the electronic photographic prints of X-rays with the help of the specified software, 2 standard for all patients zones of determination of mineral density of bone tissue, both on the extremity with partial rupture of the supraspinatus tendon and on similar parts of the contralateral limb, were found. The bone mineral density (BMD) measurement zones were placed as follows: 1st zone - the greater tubercle of the humerus; 2nd zone - the middle of the humeral head. Each zone had a square shape and corresponded to 0.9±0.15 cm² of the area of the standard radiograph. Also, all patients underwent standard radiographic examination of the hip joints and lumbar spine. Conclusions: In zone 1 (the greater tubercle of the humerus), the bone mineral density of the limb with partial tear of the supraspinatus tendon reached 0.167±0.155 g/cm² and was slightly lower than that on the healthy limb 0.238±0.115 g/cm² (p<0.05). This indicates the effect of partial rupture of the supraspinatus tendon on the development of osteoporotic processes in the area of the greater tubercle of the humerus. In the 2nd zone (the middle of the humeral head), the average bone mineral density of the limb with partial rupture of the supraspinatus tendon reached 0.193±0.109 g/cm² and was also less than 0.245±0.159 g/cm² on the contralateral limb. In the 1st zone (the greater tubercle of the humerus), the dependence of changes in bone mineral density on the total changes in bone mineral density (r=0.62; p<0.01) was revealed. In zone 2 (r=0.14; p<0.01), bone mineral density was independent of overall changes in bone mineral density.
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Wako, Masanori, Jiro Ichikawa, Kensuke Koyama, Yoshihiro Takayama, and Hirotaka Haro. "Calcific Tendinitis of the Supraspinatus Tendon in an Infant." Case Reports in Orthopedics 2020 (July 3, 2020): 1–3. http://dx.doi.org/10.1155/2020/9842489.

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Calcific tendinitis of the supraspinatus tendon in adults is common, but it is extremely rare in children. This report presents an unusual case of a 2-year-old boy with calcific tendinitis of the supraspinatus tendon. A mother brought her 2-year-old son to our hospital with a fever and severe left shoulder pain. Examination revealed a temperature of 38.6°C accompanied by a swollen shoulder with extreme pain and restricted movement. The radiographs of his left shoulder showed a large radio-opacity in the subacrominal region, and magnetic resonance imaging showed an elongated T1 and T2 hypointense signal above the supraspinatus tendon. Although these images were suggestive of calcific tendinitis of the supraspinatus tendon, we performed an open biopsy and resection in order to differentiate between a suspected diagnosis of calcific tendinitis, which is incredibly rare within pediatric patients, and infection or a soft tissue tumor. Finally, calcific tendinitis of the supraspinatus tendon was diagnosed by pathologic experiment and successfully treated, with complete resolution of pain and movement. Because only four other pediatric cases of calcific tendinitis of the supraspinatus tendon have ever been reported, there is a lack of information on the diagnostic process, management, and treatment of such a condition in young patients. Calcific tendinitis of the supraspinatus tendon still should be considered when encountering cases with typical findings even if the patient is a child.
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Zobitz, Mark E., Zong-Ping Luo, and Kai-Nan An. "Determination of the Compressive Material Properties of the Supraspinatus Tendon." Journal of Biomechanical Engineering 123, no. 1 (October 3, 2000): 47–51. http://dx.doi.org/10.1115/1.1339816.

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A methodology was developed for determining the compressive properties of the supraspinatus tendon, based on finite element principles. Simplified three-dimensional models were created based on anatomical thickness measurements of unloaded supraspinatus tendons over 15 points. The tendon material was characterized as a composite structure of longitudinally arranged collagen fibers within an extrafibrillar matrix. The matrix was formulated as a hyperelastic material described by the Ogden form of the strain energy potential. The hyperelastic material parameters were parametrically manipulated until the analytical load-displacement results were similar to the results obtained from indentation testing. In the geometrically averaged tendon, the average ratio of experimental to theoretical maximum indentation displacement was 1.00 (SD: 0.01). The average normalization of residuals was 2.1g (SD: 0.9g). Therefore, the compressive material properties of the supraspinatus tendon extrafibrillar matrix were adequately derived with a first-order hyperelastic formulation. The initial compressive elastic modulus ranged from 0.024 to 0.090 MPa over the tendon surface and increased nonlinearly with additional compression. Using these material properties, the stresses induced during acromional impingement can be analyzed.
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Chen, Si, Yuanyuan Shi, Pan Xue, and Xue Chen. "Application Value of Magnetic Resonance Arthrography of the Shoulder in Nursing and Diagnosis of Patients with Shoulder Joint Injury." Journal of Healthcare Engineering 2021 (August 23, 2021): 1–7. http://dx.doi.org/10.1155/2021/3051578.

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Supraspinatus tendon injury is a common clinical shoulder joint disease and is one of the most common causes of shoulder pain and dysfunction. Supraspinatus tendon injury will lead to articular cartilage injury and degeneration, then cause joint disease, seriously affect the quality of life of patients, and bring a huge burden to the family and society. This paper mainly studies and evaluates the application value of special signs of shoulder joint and indirect MR imaging in the diagnosis of supraspinatus tendon injury. Through a series of special examinations for the diagnosis of supraspinatus tendon injury in 90 patients, including zero degree abduction resistance test, arm drop test, Jobe test, Neer sign, and Hawkins sign, all patients in the study underwent indirect magnetic resonance imaging of the shoulder joint. Finally, arthroscopic examination results were used as the “gold standard” to evaluate and analyze the diagnosis. The results showed that among the special signs, the specificity of the falling-arm test was the highest (72.2%) in the diagnosis of full-thickness supraspinatus tendon injury. Hawkins sign had the highest sensitivity (84.0%). In the diagnosis of partial supraspinatus tendon injury, the specificity of the Jobe test was the highest, which was 66.6%. The Neer sign had the highest sensitivity of 50.0%. In the diagnosis of full-thickness supraspinatus tendon injury, there was no significant difference in sensitivity between indirect MRI and Hawkins sign, but the diagnostic specificity of indirect MRI was higher than that of special sign examination. In the diagnosis of partial supraspinatus tendon injury, the sensitivity and specificity of indirect MR imaging are higher than those of special sign examination.
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Dissertations / Theses on the topic "Supraspinatus tendon"

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Tillander, Bo. "The Supraspinatus Tendon : Clinical and histopathological aspects." Doctoral thesis, Linköping : Univ, 2001. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-5224.

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Thompson, Simon Michael. "The central tendon of the Supraspinatus : structure and biomechanics." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/24431.

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This thesis addresses changes in the supraspinatus muscle and tendon architecture, the relationship to fat infiltration and the effect of tear propagation using magnetic resonance imaging (MRI) and functional biomechanics testing using human tissues. The first hypothesis tests the relationship between the anterior and posterior portions of the supraspinatus and the central tendon when normal with no tear (NT), and pathological full thickness tears (FTT) groups. The changes in the pennation angles and central tendon associated with a FTT and the magnitude of the tear size were all statistically significant. The central tendon was found to lie anterior to the long axis of the supraspinous fossa as it passed laterally towards its insertion in the NT group. This relationship was reversed in the FTT group with the tendon lying more posteriorly or in the long axis. The second study hypothesis was that the degree of fatty infiltration of the supraspinatus is positively correlated to the maximal degree of central tendon retraction (CTR) from its insertion seen on the same MRI. The results found this relationship to be statistically significant. The aims of the cadaveric study were to establish the influence on abduction moments of full thickness tears with specific reference to tears to the central tendon. A new method of testing the biomechanics of in-vitro rotator cuff tears was developed through specimen-specific loading protocols through the use of a musculoskeletal dynamics model. A pair-wise comparison of the sections then revealed that the sectioning of the central tendon, regardless of whether the tear starts anteriorly or posteriorly, does the most significant damage to the moment producing capacity of supraspinatus. The overall contribution of this thesis is a clear understanding of the functional biomechanics of the central tendon of the supraspinatus in rotator cuff tears.
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Ohuegbe, Chyke Ihechikara. "Measurement of supraspinatus tendon strain ration with sonoelastography : an exploratory study." Thesis, University of Portsmouth, 2014. https://researchportal.port.ac.uk/portal/en/theses/measurement-of-supraspinatus-tendon-strain-ration-with-sonoelastography(61297ead-9fad-48b8-840a-d74880c2a37b).html.

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Purpose - The aim of this study was to measure the strain ratio of supraspinatus tendon, and assess the accuracy of sonoelastography when compared with grey-scale ultrasound in the diagnosis of supraspinatus tendinopathy in patients with shoulder pain. The findings were compared with clinical diagnosis and strain ratio results. Materials and Methods - The study was undertaken in three phases. In phase 1, 284 asymptomatic supraspinatus tendons of healthy volunteers were assessed by grey-scale ultrasound and sonoelastography to obtain baseline results which included strain ratio. In phase 2, 204 consecutive patients clinically diagnosed with supraspinatus tendinopathy, results of sonoelastography (index test) were compared with grey-scale ultrasound and clinical diagnosis (reference test). Strain ratio is proposed as a new reference standard and was used to test the accuracy of diagnosis. Supraspinatus tendons abnormalities detectable by grey-scale ultrasound were defined as swelling, hypoechoic or hyperechoic intratendinous lesions, while supraspinatus pathological alterations detectable by sonoelastography were defined as intratendinous tissue softening shown as experimentally proven colour changes and strain ratio values below cut-off value of 4.0 (p ≤ 0.0001). In phase 3, intra-observer and inter-observer variability evaluation was done to assess the supraspinatus tendons of healthy volunteers. Results - The overall mean strain ratio value in healthy supraspinatus tendons was 5.6 (± 1.24 SD). In healthy supraspinatus tendons, 9.9% showed evidence of softening suggesting subclinical tendinopathy which was not evident on grey-scale ultrasound. The correlation (kappa) between sonoelastography and grey-scale ultrasound in healthy volunteers was 0.42 showing moderate agreement (p < 0.001). In patients with tendinopathy, the mean strain ratio value was smaller and measured 3.59 (± 5.16 SD) with a significant statistical difference from those without tendinopathy (p = 0.001). When clinical diagnosis was used as the reference standard, sonoelastography showed better accuracy than grey-scale ultrasound {65% (CI: 59 - 70%) compared to 59% (CI: 59 - 70%)}, sensitivity {75% (CI: 60 - 86% compared to 65% (CI: 50 – 78%)} and specificity {63% (CI: 59 - 66%) compared to 57% (CI: 54 – 61%)} (p < 0.001). When strain ratio was used as the reference standard, sonoelastography also showed better accuracy than grey-scale ultrasound {92% (CI: 88 - 94%) compared to 68% (CI: 62 - 72%)}, sensitivity {98% (CI: 92 - 100%) compared to 73% (CI: 58 – 84%)} and specificity {88% (CI: 85 - 90%) compared to 67% (CI: 63 – 69%)} (p < 0.001). There was a statistically good agreement in the symptomatic group between sonoelastography and strain ratio (k = 0.84; p < 0.0005). The kappa measure of agreement between grey-scale ultrasound and sonoelastography was fair with a value of k = 0.35 (p < 0.0005). There was significant statistical difference in the mean score for the asymptomatic and symptomatic groups (p = 0.001). The kappa values for the intra-observer agreement showed very good level of agreement within each observer. Comparison of the inter-rater agreements between the two groups showed good and reproducible kappa values of 0.715 (Group 1) and 0.750 (Group 2). Conclusion - Sonoelastography has been shown to be a valuable imaging modality in the detection of intratendinous tendinopathy. It improved the accuracy, sensitivity and specificity of detection of tendinopathy when compared with grey-scale ultrasound. Strain ratio colour grading is proposed as new reference standard for supraspinatus tendinopathy.
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Riley, Graham Peter. "A biochemical analysis of the matrix of adult human supraspinatus tendon : changes with age and in rotator cuff tendinitis." Thesis, Open University, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.333395.

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Chivers, David Andrew. "Long term follow up of rotator cuff Magnetic resonance imaging changes in patients who underwent acromioplasty without repair of full thickness supraspinatus tendon tears." Master's thesis, University of Cape Town, 2015. http://hdl.handle.net/11427/16535.

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Includes bibliographical references
Aim: To assess the MRI pathoanatomical changes 10 years after unrepaired full thickness supraspinatus tears in a population of patients that had acromioplasty done for symptomatic impingement with a rotator cuff tear.
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Wang, Fang St George Clinical school UNSW. "Oxidative stress induced C-Jun N-terminal Kinase (JNK) activation in tendon cells upregulates MMP1 mRNA and protein expression." Awarded by:University of New South Wales. St George Clinical school, 2006. http://handle.unsw.edu.au/1959.4/28815.

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To explore the potential mechanisms of tendon degeneration, we investigated the role of c-Jun N-terminal Kinase (JNK) activation and the regulation of matrix metalloproteinase 1 (MMP1) in tendon matrix degradation under oxidative stress. JNK and MMP1 activity in samples from normal and ruptured human supraspinatus tendons were evaluated by immunohistochemistry. Real-time quantitative PCR was utilized to evaluate MMP1 mRNA expression and western blotting for MMP1 and JNK protein detection. JNK activation and increased MMP1 activity were found in the torn human supraspinatus tendon tissue, as well as in human tendon cells under in vitro oxidative stress. Inhibition of JNK prevented MMP1 over-expression in oxidative stressed human tendon cells. Results from the current study indicated that stress activated JNK plays an important role in tendon matrix degradation, possibly through upregulating of MMP1.
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Jonsson, Per. "Eccentric training in the treatment of tendinopathy." Doctoral thesis, Umeå : Sports Medicine, Umeå university, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-25856.

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Seto, Song P. "The development of heparin-based materials for tissue engineering applications to treat rotator cuff tendon injuries." Diss., Georgia Institute of Technology, 2014. http://hdl.handle.net/1853/51898.

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Surgical repair of torn rotator cuff tendons have a high rate of failure and does not address the underlying pathophysiology. Tissue engineering strategies, employing the use of multipotent progenitor cells or growth factors, represent potential therapies to improve the outcome of rotator cuff surgery. The use of glycosaminoglycan-based biomaterials in these therapies may enhance the effectiveness of cell and growth factor delivery techniques. Furthermore, understanding the cellular and molecular mediators in tendon overuse can help elucidate the causes of tendon degeneration. Thus the overall goals of this dissertation were to 1) develop heparin-based biomaterials to enhance cell pre-culture and maintain growth factor bioactivity and 2) characterize the histological and enzymatic changes in a supraspinatus tendon overuse model. To investigate the use of heparin in enhancing dynamic signaling, mesenchymal stem cells (MSCs) were encapsulated in heparin-containing hydrogels and evaluated for differentiation markers when cocultured with a small population of differentiated cells. To probe the effect of sulfation of heparin on the interactions with protein, selectively desulfated heparin species were synthesized and evaluated for their ability to bind and protect proteins. Finally, to develop a tendon overuse model that can become a test bed for testing future targeted therapeutics, an animal model was evaluated for tissue damage and protease activity. Together these studies represent a multi-pronged approach to understanding how tendon tissues become degenerative and for developing technologies to improve the biological fixation of tendon to bone in order to reduce the need for revision surgeries.
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Attia, Mohamed. "Mise en place d'un modèle animal de tendinopathie précoce de la coiffe des rotateurs de l'épaule en vue de développer et valider des outils technologiques préventifs et thérapeutiques." Phd thesis, Université Paris-Est, 2012. http://tel.archives-ouvertes.fr/tel-00903509.

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Les tendinopathies sont la première cause de maladie professionnelle en France. Elles sont devenues une préoccupation majeure de santé publique. Cependant, leurs mécanismes physiopathologiques restent encore mal définis. Au cours de cette thèse, nous nous sommes intéressés aux phases précoces de la tendinopathie engendrées par une sur-utilisation du tendon supra-épineux (tSE) de la coiffe de rotateurs de l'épaule chez le rat. Nous avons tenté de comprendre les mécanismes à l'origine de cette pathologie afin de pouvoir agir et la traiter en amont de l'apparition des symptômes.Nous montrons que le profil d'évolution moléculaire des collagènes, des protéoglycanes et des glycosaminoglycanes (GAGs) associé aux phases précoces de la sur-utilisation, témoigne d'un profond remaniement matriciel et d'une différenciation chondroïde des fibroblastes tendineux. Nous avons identifié les métalloprotéinases (MMPs) majeures et leurs inhibiteurs (TIMPs) susceptibles d'être impliqués dans ce remaniement. Nos résultats suggèrent que le mécanisme lésionnel initial et les changements matriciels observés sont dus à un processus induit par des médiateurs locaux libérés par les ténocytes et non à une réaction inflammatoire. Enfin, nous avons cherché à établir une corrélation entre les changements moléculaires observés et le degré de sévérité d'une tendinopathie diagnostiquée chez l'Homme. Nous avons montré, sur des échantillons de tendon patellaire humain une relation entre la quantité des GAGs et le score (VISA score) reflétant le degré pathologique du tendon.Cette étude nous a donc permis d'améliorer nos connaissances des phases précoces du processus d'altération du tSE. Cependant, d'importants efforts restent néanmoins à accomplir dans la caractérisation de la pathogenèse précoce notamment pour préciser le contexte biomécanique qui la génère.
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Mendes, João Francisco Matos. "Critical Shoulder Angle: correlation with extension and retraction of supraspinatus tendon tears." Dissertação, 2017. https://hdl.handle.net/10216/104240.

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Book chapters on the topic "Supraspinatus tendon"

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Gupta, Rishu, I. Elamvazuthi, and J. George. "Image Quality Assessment: A Case Study on Ultrasound Images of Supraspinatus Tendon." In Medical Imaging in Clinical Applications, 257–84. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-33793-7_12.

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Waldman, Steven D. "Supraspinatus Tendon Injection." In Atlas of Pain Management Injection Techniques, 65–67. Elsevier, 2013. http://dx.doi.org/10.1016/b978-1-4377-3793-6.00023-1.

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Vossen, Josephina A. "Calcium Hydroxyapatite Deposition Disease." In Musculoskeletal Imaging Volume 1, edited by Josephina A. Vossen, 173–75. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780190938161.003.0037.

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Chapter 37 discusses calcific hydroxyapatite deposition disease (HADD). Hydroxyapatite (HA) crystal deposition disease is a systemic disease of unknown etiology that is caused by periarticular and/or intraarticular deposition of HA crystals. The shoulder is the most commonly involved joint with calcification in the supraspinatus tendon, but not all patients with HADD are symptomatic. Radiography is the main diagnostic tool for HADD, which may show calcifications of varying size and shape in the periarticular tendons, bursae, and joint capsule with joint destruction. Ultrasound can be useful in evaluation and image-guided treatment of calcific tendinitis.
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Snyder, Stephen J., and James L. Bond. "Partial Articular Supraspinatus Tendon Avulsion (PASTA) Lesions of the Rotator Cuff." In The Athlete's Shoulder, 143–53. Elsevier, 2009. http://dx.doi.org/10.1016/b978-044306701-3.50015-3.

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Contreras-González, Aldo-Francisco, David Pont-Esteban, José Luis Samper-Escudero, David Cantalejo-Escobar, Miguel-Ángel Sánchez-Urán, and Manuel Ferre. "Exoesqueleto híbrido para rehabilitación de las extremidades superiores." In XLII JORNADAS DE AUTOMÁTICA : LIBRO DE ACTAS, 599–605. Servizo de Publicacións da UDC, 2021. http://dx.doi.org/10.17979/spudc.9788497498043.599.

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The last decades have witnessed a rapid and vast development of robots for physical rehabilitation that allow efficient planning of the rehabilitation process in terms of cost, duration of sessions and availability of the therapist. This project aims to qualitatively evaluate an exoskeleton for upper body rehabilitation. The device presents an approach to the development of a device with the end-effector anchored to the ground that performs the actuation on an exoskeleton coupled to the body of the subject by cables. Experimentation with patients suffering from the supraspinatus tendon is documented by performing a series of movements dictated by a doctor.
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Gupta, Rishu, Irraivan Elamvazuthi, and John George. "Development of Ultrasound Imaging CAD Tool for Assessment of Pathologies in Supraspinatus Tendon." In Medical Imaging, 614–54. IGI Global, 2017. http://dx.doi.org/10.4018/978-1-5225-0571-6.ch024.

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Non-invasive diagnostic imaging methods for diagnosis of pathological conditions is increasingly gaining popularity resulting from speedy and effective recovery during follow up in several clinical trials. The accuracy of the diagnosis depends on the experience and knowledge of physicians conducting the trial. In such scenario, the need for quantitative measures for details such as shape and size of tissue can assist physicians for better intuitive understanding of tissue and its pathologies. Computer aided diagnosis (CAD) tool incorporating methods for segmentation, texture analysis and area computation can increase the accuracy of diagnosis by providing quantitative analysis of the image. This chapter briefly describes issues and challenges for building the CAD tool followed by brief description about the methods involved. The methods are validation are also discussed briefly. To summarize the work, brief discussion about a new software or CAD tool for diagnosis of pathologies supraspinatus tendon with the help of ultrasound images is provided. The new software has an intuitive user interface which is easy, quick and suitable for medical work.
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Waldman, Steven D. "The external rotation lag sign for rupture of the supraspinatus or infraspinatus tendon." In Physical Diagnosis of Pain, 104–104. Elsevier, 2021. http://dx.doi.org/10.1016/b978-0-323-71260-6.00071-x.

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Clunie, Gavin, Nick Wilkinson, Elena Nikiphorou, and Deepak R. Jadon. "Common upper limb musculoskeletal lesions." In Oxford Handbook of Rheumatology, edited by Gavin Clunie, Nick Wilkinson, Elena Nikiphorou, and Deepak R. Jadon, 595–604. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198728252.003.0020.

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This chapter introduces readers to some common upper limb musculoskeletal lesions, including subacromial (shoulder) impingement syndrome, adhesive capsulitis, and lateral epicondylitis (tennis elbow). The epidemiology, aetiopathogenesis, clinical presentation, and management of these conditions are presented. Algorithms for their management are provided. Other disorders presenting with a subacromial impingement pattern of pain are detailed and optimal diagnostic imaging methods proposed. These include supraspinatus/cuff tendonitis, subacromial bursitis, rotator cuff tear, long head of biceps tendonitis, osteophyte impingement on the rotator cuff tendon, glenohumeral instability due to labral trauma (e.g. SLAP lesion), arthritis of the glenohumeral joint, enthesitis related to spondyloarthritis, and lesions at the suprascapular notch.
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Conference papers on the topic "Supraspinatus tendon"

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Thornton, Gail M., Xinxin Shao, May Chung, Paul Sciore, Richard S. Boorman, David A. Hart, and Ian K. Y. Lo. "Mechanical Loading Uniquely Up-Regulates MMP-13 in Rat Supraspinatus Tendon But Not Achilles Tendon." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-173778.

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Tendon injuries and chronic pain, known as tendinopathy, are extremely common in supraspinatus and Achilles tendons. Despite their prevalence, the pathogenesis of these conditions is poorly understood. One of most common cited factors for injuries to the rotator cuff tendons is “impingement”, namely, mechanical compression of the supraspinatus tendon by the overlying coracoacromial arch [1]. To date, few studies have investigated the molecular processes underlying this condition.
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Reuther, Katherine E., Stephen J. Thomas, Jennica J. Tucker, Joseph J. Sarver, Chancellor F. Gray, Elisabeth B. Evans, Sarah Ilkhani-Pour, David L. Glaser, and Louis J. Soslowsky. "Returning to Overuse Activity Following a Combined Supraspinatus and Infraspinatus Tear Leads to Shoulder Joint Damage." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14464.

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Rotator cuff tendon tears are common conditions which can lead to significant pain and dysfunction. Tears may progress over time from isolated supraspinatus tears to complete ruptures of both the supraspinatus and infraspinatus tendons, disrupting the anterior-posterior force balance provided by the subscapularis anteriorly and infraspinatus posteriorly (commonly referred to as a “force couple”) [1]. This disruption may lead to increased joint instability and result in altered glenohumeral translations which may cause damage to joint structures, such as articular cartilage and adjacent (intact) tendons. This is a particular concern for active individuals who are likely to continue high levels of overuse activity (e.g., laborers, athletes), despite the presence of rotator cuff tears. Previous studies have shown that returning to overuse activity following an isolated supraspinatus tear alters biceps and glenoid articular cartilage properties, but does not alter shoulder function or the adjacent intact subscapularis tendon [2]. However, the consequences associated with disrupting the anterior-posterior force balance (supraspinatus and infraspinatus tears) are not understood. Therefore, the objectives of this study were 1) to investigate the effect of returning to overuse activity following tears of both the supraspinatus and infraspinatus tendons on shoulder function and the remaining intact tendon and glenoid cartilage mechanical properties and 2) to begin to define the biologic mechanisms responsible for these changes. We hypothesized that overuse activity following two-tendon rotator cuff tears would H1) alter shoulder function and H2) lead to damage (indicated by inferior mechanical properties and increased production of degenerative factors, extracellular matrix, and cartilage markers) in the remaining intact tendons (including the biceps and upper and lower subscapularis tendons) and in the anterior-superior region of the glenoid articular cartilage as a result of the excessive joint loading due to overuse following the supraspinatus-infraspinatus tear.
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Miller, R. Matthew, Daisuke Araki, Yoshimasa Fujimaki, Volker Musahl, and Richard E. Debski. "Correlation Between Age and Tendon Strength in Supraspinatus Tendon With Full-Thickness Tears." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14037.

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Degenerative tears of the rotator cuff tendons are a significant clinical problem, with an incidence of more than 30% in asymptomatic persons over the age of 60 [1]. As the population continues to age, the incidence of partial and full-thickness rotator cuff tears continues to increase [2], with previous studies finding that greater age also correlates with worse surgical outcomes and increased fatty degeneration in the tissue [3]. Although the relationship between age, rotator cuff injury, and poor treatment outcomes has been previously established, insufficient information exists on the biological and mechanical changes in the tissue due to aging.
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Szczesny, Spencer E., John Peloquin, Sarah Ilkhani-Pour, Daniel H. Cortes, Jennifer A. Kadlowec, Louis J. Soslowsky, and Dawn M. Elliott. "Continuity and Affine Fiber Kinematics in Biaxial Tension of the Supraspinatus Tendon." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53588.

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The human supraspinatus tendon (SST) exhibits strong heterogeneity in fiber alignment and material properties [1,2]. The relationship between fiber angle distribution and material properties has been previously described by a structurally based continuum model [3], which provided new quantitative structure-function relationships to explain the observed SST heterogeneity; however, in some locations and testing directions, the model predictions were not consistent with a continuum assumption [3]. More recent analysis of the change in fiber angle during loading showed that samples with less aligned fibers have less affine kinematics in uniaxial tensile loading [4]. That is, in uniaxial tensile testing, where the transverse edges freely contract, the fiber strain did not match the tissue strain. Because the SST is somewhat transversely constrained by surrounding rotator cuff structures in vivo and has distributed fibers to support multidirectional loading, the freely contracting edges of uniaxial tension may not appropriately constrain the tendon. Therefore, the objective of this study was to evaluate SST stress-strain behavior and affine deformation under biaxial tension. Specifically, if behaving as a continuum, we expected that applying a fixed boundary condition in the transverse direction would produce a higher apparent modulus, a smaller toe-region, and more affine fiber realignment than a free boundary condition.
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Killian, Megan L., and Stavros Thomopoulos. "The Role of Scleraxis in Supraspinatus Enthesis Development." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80354.

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High localized stresses can develop at the interface between dissimilar materials; their attachment is therefore a major engineering challenge. During the development of the tendon-to-bone attachment (the “enthesis”), tendon transitions into fibrocartilage and then into mineralized fibrocartilage as it inserts into bone [1,2]. While natural development leads to a strong and tough enthesis, surgical reattachment and healing of tendon to bone often fails [3]. Thus, a better understanding of the developmental cues necessary for enthesis formation may help to navigate future repair and tissue engineering approaches for tendon-to-bone repair.
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Kadlowec, Jennifer A., Spencer P. Lake, Kristin S. Miller, Louis J. Soslowsky, and Dawn M. Elliott. "A Hyperelastic Model With Distributed Fibers to Describe Human Supraspinatus Tendon Tensile Mechanics." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206509.

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Tendon tissue is composed of collagen fibers in a hydrated proteoglycan matrix. Although many tendons have fibers that are highly aligned (e.g. flexor tendon), the supraspinatus tendon (SST) of the shoulder has significant distribution of fiber alignment [1]. The alignment and distribution of the fibers likely contributes to the nonlinear and anisotropic mechanical behavior, however this has not been demonstrated. Understanding the role of fiber structure on tendon mechanical behavior, that is, characterizing the structure-function relationships, is critical to evaluate the function of injured, degenerated, or healing tendons and would be invaluable in the design and assessment of tissue engineered tendon replacements. While a structurally based hyperelastic model has been developed for tendon [2], this model contained only a single fiber orientation, which is not adequate for the more distributed fiber structure in the SST. We have recently applied a hyperelastic model formulation that has distributed collagen fiber orientation developed by Gasser and colleagues for the arterial wall [3] to model a tendon analog made from nanofibrous scaffolds [4]. The objective of this study was to build on previous work to apply a hyperelastic fiber-reinforced constitutive model that includes a specific term for fiber distribution to the tensile mechanics of human SST and to evaluate the site-specific model material properties.
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Szczesny, S. E., J. M. Peloquin, D. H. Cortes, J. Kadlowec, L. J. Soslowsky, and D. M. Elliott. "Biaxial tensile testing and constitutive modeling of human supraspinatus tendon." In 2012 38th Annual Northeast Bioengineering Conference (NEBEC). IEEE, 2012. http://dx.doi.org/10.1109/nebc.2012.6206986.

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Miller, Kristin S., Lena Edelstein, and Louis J. Soslowsky. "Effect of Preconditioning on Collagen Fiber Recruitment: Inhomogeneous Properties of Rat Supraspinatus Tendon." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19089.

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Cyclic preconditioning is a commonly accepted initial component of any tendon testing protocol. Preconditioning provides tendons with a consistent “history” and stress-strain results become repeatable allowing for rigorous evaluation and comparison. While it is widely accepted that preconditioning is important, changes that occur during preconditioning are not well understood. Micro-structural alterations, such as re-arrangement of collagen fibers, is one proposed mechanism of preconditioning [1,4]. However, this mechanism has not been examined. Therefore, the objective of this study is to locally measure: 1) fiber re-alignment during preconditioning, stress relaxation and tensile testing and 2) corresponding mechanical properties, to address mechanisms of preconditioning as well as tissue nonlinearity and inhomogeneity in the rat supraspinatus tendon. We hypothesize that 1) fiber re-alignment will be greatest in the toe region, but will also occur during preconditioning and 2) mechanical properties and initial collagen fiber alignment will be greater in the midsubstance location of the tendon compared to the tendon-to-bone insertion site.
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Tuite, M., A. U. Patel, T. Scerpella, B. Chan, G. Baer, and J. Orwin. "Supraspinatus and Infraspinatus Tendon Tears: New Insights from Recent Anatomical Studies." In 26th Annual Scientific Meeting of the European Society of Musculoskeletal Radiology (ESSR). Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1692583.

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Reuther, Katherine E., Stephen J. Thomas, Joseph J. Sarver, Jennica J. Tucker, Chang-Soo Lee, Chancellor F. Gray, David L. Glaser, and Louis J. Soslowsky. "Massive Cuff Tears Alter Joint Function and Decrease Cartilage Mechanics Following Return to Overuse Activity in a Rat Model." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80072.

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Rotator cuff tendon tears are common conditions which can alter shoulder joint function and over time, cause secondary damage to the surrounding tissues, including the cartilage and other remaining tendons. Glenohumeral joint stability is dependent on a dynamic balance between rotator cuff forces, in particular the subscapularis anteriorly and the infraspinatus posteriorly. An intact rotator cuff stabilizes the joint, allowing for concentric rotation of the humeral head on the glenoid. However, a massive rotator cuff tear involving the supraspinatus and infraspinatus may disrupt the normal balance of forces at the joint, resulting in abnormal joint loading. This is of particular concern in populations who perform activities requiring repeated overhead activity (e.g., laborers, athletes). Our lab has previously demonstrated that restoration of the subscapularis-infraspinatus anterior-posterior force balance improves shoulder function by providing a stable fulcrum for concentric rotation of the humeral head on the glenoid [1]. However, the long term consequences caused by disruption of the anterior-posterior force balance (supraspinatus and infraspinatus tear) on the glenoid cartilage and adjacent (intact) tendons, particularly in the case of an overuse population, remains unknown. Therefore, the objective of this study was to investigate the effect of disrupting the anterior-posterior force balance on joint function and joint damage using a clinically relevant overuse model system. We hypothesized that a disrupted anterior-posterior force balance (supraspinatus and infraspinatus tear) would result in H1) decreased joint function and H2) inferior adjacent tissue (glenoid cartilage, biceps and subscapularis tendon) properties compared to an intact anterior-posterior force balance (supraspinatus only tear).
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