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Darmayanti, Vavia, Syahrial Syahrial, and Wisma Yunita. "Analysis of Supplementary Reading Material Based on Students’ Preference." Jadila: Journal of Development and Innovation in Language and Literature Education 1, no. 3 (February 28, 2021): 271–83. http://dx.doi.org/10.52690/jadila.v1i3.50.
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The aims of this study were to find out the types of text of supplementary reading material chosen by students based on their preference and to investigate the students’ reasons in choosing the types of text of supplementary reading material at grade VIII of SMPN 1 Kepahiang. This research was categorized as descriptive quantitative and qualitative research. The subjects were the students of grade VIII who are chosen by using semi random sampling. The data was collected by using text types list and open ended questions. The researcher asked the students to choose types of text which were prefered by them, from total 50 texts the students must choose twenty texts. Then, to know the reason why they chose those texts, the researcher did an open ended questions to 20 students randomly. There were two findings of this research; (1) the type of text for supplementary reading material chosen by mostly students based on their preference at grade VIII of SMPN 1 Kepahiang was narrative text; (2) there were three students’ reasons in choosing the types of text for supplementary reading material at grade VIII of SMPN 1 Kepahiang, they were; the narrative text contains some stories which can entertain them, the narrative text is interesting to read, and the narrative text is easy to understand. Due to the limited sample taken in this research and the situation on Covid-19, it was suggested for further researcher to conduct similar research in more numbers of sample by conducting research in the classroom directly.
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Khoza, Michael, Hala M. Abdel Mageed, Abdelkarim Mallat, Rasha Sayed Attiya Mohammed, Gibson Aguko, Abdellah ZITI, Patrick Kizito Musaazi, and Nesredin Nezir. "AFRIMETS.EM-S1 supplementary comparison of resistance standards." Metrologia 59, no. 1A (January 1, 2022): 01003. http://dx.doi.org/10.1088/0026-1394/59/1a/01003.
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Main text AFRIMETS.EM-S1 supplementary comparison on resistance standards at 1 Ω, 10 Ω, 100 Ω, 1 kΩ and 10 kΩ commenced November 2015 and ended June 2018. The comparison approved by AFRIMETS technical committee for Electricity and Magnetism (TC-EM) and Consultative Committee for Electricity and Magnetism (CCEM). Seven National Metrology Institutes participated including National Metrology Institute of South Africa (NMISA)the pilot laboratory. The primary objective of the comparison is aimed to underpin and strengthen the capabilities of the National Metrology Institutes and establish the degree of equivalence and comparability. The results of the participants are found to be equivalent, comparable and in agreement with the comparison reference values within stated uncertainties of measurements. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database https://www.bipm.org/kcdb/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
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Sutanti, Nita, Hesty Puspita Sari, and Galuh Karina. "DEVELOPING RECOUNT TEXT MATERIALS BASED ON K13 CURRICULUM FOR THE TENTH GRADE STUDENTS OF SENIOR HIGH SCHOOL." Konstruktivisme : Jurnal Pendidikan dan Pembelajaran 11, no. 1 (January 1, 2019): 53–65. http://dx.doi.org/10.35457/konstruk.v11i1.666.
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This research was aim to develop recount text materials to the tenth grader students of senior high school and find out the effectiveness of the recount text materials. This research was done in SMAN 1 Ponggok. The researcher used Research and Development (R & D) adopted from of Sugiyono’s model (2015:298) to conduct the research. The data collected through interview, questionnaire, documentation, and test. The expert validation which used in this research were; 1) media expert 2) material expert. To try out the product, the researcher used one group pre-test and post-test experimental design. The results of the research showed that the develop of Recount Text Material was effective; it proved by 1) The result of material validation 98.18% and media validation 96.25 %. The average of those two validation is 97,22% that categorized as “very good” by interval 80% < x ≤ 100%. So, the supplementary book of Recount text Material which developed was valid to be implemented in the tenth grader of Senior high school students. 2) It also increase the tenth grade students’ writing achievement that proved by the increase of the students’ of pre test mean score (66.67) to post test mean score (83.83). 3) The students also gave positive responses toward Recount Text Material as reflected from the result of the questionnaire given (85.8%). From that result presented before, it can be concluded that Recount Text Material was effective and increased the tenth grade students’ writing achievement. It means Recount Text Material can be used as a supplementary media for learning English writing.
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SUN, JIANSHE. "ANALYTICAL APPROXIMATE SOLUTIONS OF (N + 1)-DIMENSIONAL FRACTAL HARRY DYM EQUATIONS." Fractals 26, no. 06 (December 2018): 1850094. http://dx.doi.org/10.1142/s0218348x18500949.
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The new fractal models of the [Formula: see text]-dimensional and [Formula: see text]-dimensional nonlinear local fractional Harry Dym equation (HDE) on Cantor sets are derived and the analytical approximate solutions of the above two new models are obtained by coupling the fractional complex transform via local fractional derivative (LFD) and local fractional reduced differential transform method (LFRDTM). Fractional complex transform for functions of [Formula: see text]-dimensional variables is generalized and the theorems of [Formula: see text]-dimensional LFRDTM are supplementary extended. The travelling wave solutions of the fractal HDE show that the proposed LFRDTM is effective and simple for obtaining approximate solutions of nonlinear local fractional partial differential equations.
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Kafkas, Şenay, Jee-Hyub Kim, Xingjun Pi, and Johanna R. McEntyre. "Database citation in supplementary data linked to Europe PubMed Central full text biomedical articles." Journal of Biomedical Semantics 6, no. 1 (2015): 1. http://dx.doi.org/10.1186/2041-1480-6-1.
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Wood, Mary A., Austin Nguyen, Adam J. Struck, Kyle Ellrott, Abhinav Nellore, and Reid F. Thompson. "neoepiscope improves neoepitope prediction with multivariant phasing." Bioinformatics 36, no. 3 (August 19, 2019): 713–20. http://dx.doi.org/10.1093/bioinformatics/btz653.
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Abstract Motivation The vast majority of tools for neoepitope prediction from DNA sequencing of complementary tumor and normal patient samples do not consider germline context or the potential for the co-occurrence of two or more somatic variants on the same mRNA transcript. Without consideration of these phenomena, existing approaches are likely to produce both false-positive and false-negative results, resulting in an inaccurate and incomplete picture of the cancer neoepitope landscape. We developed neoepiscope chiefly to address this issue for single nucleotide variants (SNVs) and insertions/deletions (indels). Results Herein, we illustrate how germline and somatic variant phasing affects neoepitope prediction across multiple datasets. We estimate that up to ∼5% of neoepitopes arising from SNVs and indels may require variant phasing for their accurate assessment. neoepiscope is performant, flexible and supports several major histocompatibility complex binding affinity prediction tools. Availability and implementation neoepiscope is available on GitHub at https://github.com/pdxgx/neoepiscope under the MIT license. Scripts for reproducing results described in the text are available at https://github.com/pdxgx/neoepiscope-paper under the MIT license. Additional data from this study, including summaries of variant phasing incidence and benchmarking wallclock times, are available in Supplementary Files 1, 2 and 3. Supplementary File 1 contains Supplementary Table 1, Supplementary Figures 1 and 2, and descriptions of Supplementary Tables 2–8. Supplementary File 2 contains Supplementary Tables 2–6 and 8. Supplementary File 3 contains Supplementary Table 7. Raw sequencing data used for the analyses in this manuscript are available from the Sequence Read Archive under accessions PRJNA278450, PRJNA312948, PRJNA307199, PRJNA343789, PRJNA357321, PRJNA293912, PRJNA369259, PRJNA305077, PRJNA306070, PRJNA82745 and PRJNA324705; from the European Genome-phenome Archive under accessions EGAD00001004352 and EGAD00001002731; and by direct request to the authors. Supplementary information Supplementary data are available at Bioinformatics online.
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Mustangin, Muhammad, and Yuyun Yulia. "Supplementary reading materials for “When English rings the bell”." Journal of English Language and Pedagogy 2, no. 2 (November 18, 2019): 84. http://dx.doi.org/10.36597/jelp.v2i2.4867.
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This study is aimed at developing supplementary reading materials based on “When English Rings the Bell” and describing the effectiveness of the developing supplementary reading. This research belongs to Educational Research and Development (R&D) which are simplified into six steps. They are (1) data collection by document analysis, questionnaire, interview, product testing, as well as experts’ judgment, (2) constructing the course grid (Nation & Macalister, 2010), (3) draft revision by experts, (4) developing product to the preliminary outcome, (5) evaluation and revision of the product, and (6) final product. The findings show that students’ necessity to learn English is to be able to comprehend English (82.35%) and to increase vocabulary (50%) with interesting text. However, in other hand, their lack in vocabulary (52.94%) and the activities are too various (44%). The targeted materials are Getting My Idea for the descriptive text, My Pleasant Experience for the recount text, and Tell Me Your Story for the narrative text. Each unit consists of introduction, learning procedure, reinforcement, and wise word. Accordingly, the effectiveness of the product helps students to achieve the targeted competences. The students were actively participating in answering the task. The supplementary reading could help students to achieve students’ need and to improve their participation in reading skill. Furthermore, the reading materials as the product of this study providing additional learning resources.
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Chun, Sejong, and Noriyuki Furuichi. "Final report of the APMP water flow supplementary comparison (APMP.M.FF-S1)." Metrologia 59, no. 1A (January 1, 2022): 07004. http://dx.doi.org/10.1088/0026-1394/59/1a/07004.
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Main text A supplementary comparison, entitled as APMP.M.FF-S1, has been undertaken between KRISS and NMIJ, AIST under the supervision by the Technical Committee for Fluid Flow (TCFF) in the Asia Pacific Metrology Programme (APMP). The purpose of this supplementary comparison was to prove the measurement equivalence between NMIJ, AIST and KRISS for water flow measurement standards from 300 m3/h to 1 200 m3/h. This supplementary comparison was meaningful because there has not been an international comparison for water flows greater than 300 m3/h. Previous key comparisons have been performed only from 30 m3/h to 200 m3/h [1]. Therefore, this supplementary comparison became the first inter-laboratory comparison to cover the flow range for large-capacity water flow measurement standards. In fact, the inter-laboratory comparison between NMIJ, AIST and PTB (Berlin) has been already done for such flowrate range [2], however, this inter-laboratory comparison has not been supervised by APMP or EURAMET, such that the result of inter-laboratory comparison is published in a research journal, not in the BIPM KCDB for inter-laboratory comparisons. A turbine flow meter with the pipe diameter of 250 mm was chosen as a transfer standard in this supplementary comparison. A flow conditioner was used to define inflow conditions upstream of the turbine flow meter. The flow conditioner was a perforated plate with a well-known design. The turbine flow meter was calibrated in two ways: with or without the flow conditioner. The calibration of turbine flow meter with the flow conditioner was according to the revised test protocol for this supplementary comparison. The other calibration without the flow conditioner was performed to investigate the flow characteristics of the turbine flow meter. K-factor was the measurand to evaluate the measurement equivalence between NMIJ, AIST and KRISS. The K-factor was corrected by considering the temperature change between the water temperature and the reference temperature of 20 oC [3]. The measurement uncertainty of the K-factor included uncertainty factors such as repeatability, day-to-day reproducibility, re-installation effect, long-term stability, and the influence by temperature change. Inconclusiveness test was also performed to see whether the K-factor was suitable for evaluating the number of equivalence between NMIJ, AIST and KRISS. The number of equivalence was found to be less than 1. The number of equivalence became better in the case without the flow conditioner than the case with the flow conditioner. The number of equivalence was found to be conclusive because the inconclusiveness index was less than 2. Therefore, the measurement equivalence between NMIJ, AIST and KRISS has been proven by this supplementary comparison. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database https://www.bipm.org/kcdb/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
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Azizah, Dinar Martia, and Sugirin Sugirin. "The Environment-Based Supplementary Reading Materials for Junior High School Students." Journal of Interdisciplinary Studies in Education 8, no. 1 (June 30, 2019): 154–74. http://dx.doi.org/10.32674/jise.v0i0.1034.
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One such effort toward this is the development of environment-based supplementary reading materials for students. In accordance with this, the objectives of this research are: 1) to investigate the need of junior high school students for environment-based supplementary reading materials; and 2) to develop environment-based supplementary reading materials suitable for these students. The subjects of this research and development were eighth grade students of a junior high school. The procedure utilized is a modified version of the research and development steps proposed by Borg & Gall and included four development procedures. The stages of this modified procedure were: 1) the exploration stage, including need analysis; 2) the prototype development stage, including planning and developing the format/draft; 3) the revision stage, using expert evaluation; and 4) the finalization stage. The resulting supplementary reading material has been developed into 3 units, with the texts being recount, descriptive, and narrative. Each unit consists of a list of new vocabulary, a comic, a main text, and exercises. The exercises at the end of each unit have the purpose of confirmation.The texts aim to convey an ideal relationship between humans and environment.
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Langer, Philip, Verne Keenan, and M. E. Schreiner. "Assisting Text Processing: What Do We Need to Consider." Psychological Reports 76, no. 3 (June 1995): 835–45. http://dx.doi.org/10.2466/pr0.1995.76.3.835.
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42 undergraduates were presented one of two 25-sentence versions of a fictitious town. One version (route) described the town as a driver might encounter it, while the other (survey) received a geographic description. Sentences were printed one to a card and read aloud. Feedback included (1) limited access to a map, (2) limited opportunity to review previously read sentences, or (3) presentation of entire text after processing. Memorial representation was assessed by either propositional recall or inferential reasoning. In this study subjects also reviewed the text prior to either the prepositional recall or inferential memory task. Recall for the survey version was enhanced, but there was no reliable effect on inferential reasoning. Although not statistically significant, the text by feedback interactions suggested both complementary and supplementary effects of assistance should be studied further.
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Saryati, Titik, and Yuyun Yulia. "Contextual teaching and learning approach to supplementary reading materials based on 2013 Curriculum." Journal of English Language and Pedagogy 2, no. 1 (April 7, 2019): 1. http://dx.doi.org/10.36597/jelp.v2i1.3703.
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The objectives of this study are to (1) develop supplementary reading materials using Contextual Teaching and Learning Approach for students of SMP N 1 Moyudan and (2) describe the efficacy of the supplementary reading materials. This research belongs to Educational Research and Development (R&D) using a simplified six steps of (Gall, Gall, & Borg, 2003) model. The finding shows that the students learn English to achieve the 2013 curriculum learning objectives. The necessities of the teaching and learning English is to improve students' English skills so that they gain good score for the national examinations though students have less motivation to learn reading and they cannot learn independently. They cannot differentiate or understand WH-questions that is important in learning reading. The efficacy of this product helps students to improve their reading skill especially to understand the topic, the generic structure, the main idea, the grammar and the vocabulary used in the text. The supplementary reading materials as the product of this study provide additional learning resources for students.
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Pratama, Ikke Dewi, Woro Retnaningsih, and Muhammad Romdhoni Prakoso. "Interlingual Subtitles to Increase High School Students’ Ability in Understanding Explanation Texts." Metathesis: Journal of English Language, Literature, and Teaching 5, no. 1 (April 8, 2021): 19. http://dx.doi.org/10.31002/metathesis.v5i1.2701.
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<p>This paper explores the use of interlingual subtitle as a media in teaching reading skill in one of private high schools in Surakarta. This research was initially conducted as the teachers found problems in teaching genres of texts, especially explanation text. Interlingual subtitle which is placed in videos is offered by the researchers as a solution and expected to help students in understanding the content of explanation text. This research uses classroom action research method with two cycles. The objectives of this research are to find out: 1) the implementation of interlingual subtitle in teaching explanation text, and 2) the impacts of interlingual subtitle on students’s achivements. The subjects of this research are 33 students of social science class and 33 students of natural science class. It is found out that interlingual subtitle can be used as a supplementary material in teaching explanation text. Interlingual subtitle has also contributed positively to the increasing scores of the students during the pre-test to the post-test.</p><p> </p>
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Meinhold, Guido. "Franz Kossmat – Subdivision of the Variscan Mountains – a translation of the German text with supplementary notes." History of Geo- and Space Sciences 8, no. 1 (April 24, 2017): 29–51. http://dx.doi.org/10.5194/hgss-8-29-2017.
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Abstract. This work is in honour of Franz Kossmat (1871–1938) and his esteemed paper the Gliederung des varistischen Gebirgsbaues published 1927 in Abhandlungen des Sächsischen Geologischen Landesamts, Volume 1, pages 1 to 39. It constitutes the foundation of the general subdivision of the Central European Variscides into several geotectonic zones and the idea of large-scale nappe transport of individual units. In the English translation presented here an attempt is made to provide a readable text, which should still reflect Kossmat's style but would also be readable for a non-German speaking community either working in the Variscan Mountains or having specific interests in historical aspects of geosciences. Supplementary notes provide information about Kossmat's life and the content of the text. Kossmat's work is a superb example of how important geological fieldwork and mapping are for progress in geoscientific research.
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Amino, Yoshihiko. "MEDIEVAL JAPANESE CONSTRUCTIONS OF PEACE AND LIBERTY: MUEN, KUGAI AND RAKU, SUPPLEMENTARY NOTES." International Journal of Asian Studies 4, no. 2 (June 26, 2007): 161–72. http://dx.doi.org/10.1017/s1479591407000708.
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AbstractThe main text upon which these notes are based (Muen, kugai, raku) was first published as a chapter in a book of essentially the same name in 1978. When the revised edition of the work was published in 1996, voluminous notes were added as an appendix, as a way for Amino to reply to his critics. The present article consists of three notes, one on raku, one on kugai and one comparing the three raku, kugai and muen with the idea of “liberty” (Amino's preferred translation for the Japanese term jiyū). To recapitulate the main text (whose translation appeared in IJAS 4:1), all three terms, originally Buddhist, were used as secular concepts in medieval times to denote people and places outside the control of the political authority. All were characterized by certain “freedoms” or “liberties”, but such connotations disappeared in the course of the seventeenth century with the unification of the country.
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Deng, Zhangyan, Jinyang Guo, Dong Wang, and Zuosong Chen. "A Supplementary Approach for Effective Anti-Doping Education: A Pilot Study Applying Refutation Texts to Modify Misperception of the Whereabouts System." International Journal of Environmental Research and Public Health 19, no. 4 (February 13, 2022): 2097. http://dx.doi.org/10.3390/ijerph19042097.
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Background: Over the past twenty years, a multifaceted anti-doping system was established to detect, deter, and prevent doping among athletes. However, perception of the whereabouts system has been a controversial issue. This pilot study aimed to evaluate the effects of refutation text intervention on the perception of the whereabouts system. Methods: In two studies, we tested whether (1) detailed refutation texts are perceived as more effective than simply refuting with a true or false claim among 132 athletes (47.73% female, mean age = 20.99 ± 2.11), and if (2) refutation text intervention can alter the perception of the whereabouts system among 177 athletes (53.11% female, mean age = 21.17 ± 2.27). Descriptive statistics were calculated, followed by a one-sample T-test, independent T-test, chi-square test, and a repeated-measures analysis of variance. Results: The results demonstrate that five true/false statements were developed as refutation texts, and the mean accuracy of the true/false test is less than the probability of guess (p < 0.05, d = −0.18). In addition, detailed refutation texts evoked significantly greater perceived effectiveness than the simple refutation texts (p < 0.01, d = 0.66). Furthermore, the refutation text intervention enhanced the positive perception of the whereabouts system (p < 0.01, η2 = 0.15). Conclusions: Our findings support the efficacy of refutation texts to improve the misperception of anti-doping regimes among athletes and have implications for future education prevention initiatives.
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Philipp, R., B. Lalere, F. Gantois, C. Sánchez, A. Sáez, J. Bebić, K. Banjanac, et al. "Supplementary comparison study - measurement capabilities for the quantification of ethanol in water." Metrologia 59, no. 1A (January 1, 2022): 08015. http://dx.doi.org/10.1088/0026-1394/59/1a/08015.
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Main text The accurate quantification of ethanol in water is essential for forensic applications such as blood and breath alcohol testing and for commercial applications such as the assessment of alcoholic beverages. The intercomparison EURAMET.QM-S14 is part of a capacity building project named ALCOREF "Certified forensic alcohol reference materials" [1] that is running within the European Metrology Programme for Innovation and Research (EMPIR) [2]. The intercomparison should allow project partners and other interested National Metrology Institutes (NMIs) and Designated Institutes (DIs) to benchmark their analytical methods for the quantification of ethanol in water. The study plan was agreed by the European Association of National Metrology Institutes (EURAMET) Subcommittee Bio- and Organic Analysis (SCBOA) and the Organic Analysis Working Group (OAWG) of the Comité Consultatif pour la Quantité de Matière (CCQM) in February and April 2019, respectively. The intercomparison was coordinated by BAM. Two concentration levels relevant for the calibration and verification of evidential breath alcohol analysers were distributed to study participants. Fifteen institutes from 15 countries registered for the intercomparison and returned results. Participants mostly applied gas chromatography with flame ionisation detection (GC-FID) or mass spectroscopy (GC-MS), one participant used titrimetry and one participant employed a test bench for breath analyser calibration ("bubble train"). Participants did either in-house purity assessment of their commercial ethanol calibrants by Karl-Fischer titration, chromatographic methods, quantitative nuclear magnetic resonance spectroscopy (qNMR) and/or density measurements; or they used ethanol/water Certified Reference Materials (CRMs) from NMIs/DIs for calibration. CCQM OAWG agreed to use a consensus value from participants' results that utilizes the reported uncertainties as Key Comparison Reference Value (KCRV). The Gaussian Random effects model with Hierarchical Bayesian solution (HB-REM) is a reasonable approach in this case. The KCRVs and Degrees of Equivalence (DoEs) were calculated with the NIST consensus builder version 1.2 Hierarchical Bayes procedure [3]. Successful participation in the interlaboratory comparison has demonstrated the capabilities in determining the mass fraction of ethanol in aqueous matrices in the range 0.1 mg/g to 8 mg/g. Fourteen out of 15 participants have successfully quantified both samples, one participant successfully quantified only the lower-level (0.6 mg/g) sample. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database https://www.bipm.org/kcdb/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
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Berlin, Astri Winandari, Rahayu Apriliaswati, and Yanti Sri Rezeki. "Developing E-Module of Islamic Reading Text Materials." Journal of Foreign Language Teaching and Learning 7, no. 1 (January 12, 2022): 24–40. http://dx.doi.org/10.18196/ftl.v7i1.13210.
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Providing English learning material with an Islamic basis for Madrasah Aliyah students is important as the students are Islamic learners. This research aims to develop an e-module of Islamic reading text materials for the second semester of tenth-grade students of MAN 1 Pontianak. The researchers adapted the Analyze, Design, and Develop phases of the ADDIE concept to develop this research product. The analysis phase was conducted by interviewing the English teacher to determine the suitable e-module to be designed. The design phase was done by designing the contents of the e-module based on the analysis results. The e-module consists of recount and narrative texts materials with Islamic-based stories and integrates the values of aqidah (strong belief), tawakkul (reliance upon Allah), tolerance, hard work, and husnuzon (positive thinking). In the development phase, the researchers developed the e-module then checked it with a self-designed standard evaluation checklist. The result showed that the e-module already fulfilled the criteria of appropriateness. The e-module could be supplementary reading materials to make the students’ autonomous learning easier. It was written in easy-to-understand language and provided self-instructional material with independent self-evaluation. Specifically, it is expected to improve their understanding of recount and narrative text materials and strengthen their Islamic character values.
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Rudian, Rudian, and Imam Ghozali. "Developing supplementary English reading module for tenth-grader of senior high school SahabatQu Yogyakarta." Journal of English Language and Pedagogy 4, no. 1 (June 10, 2021): 48–59. http://dx.doi.org/10.36597/jelp.v4i1.11021.
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The objectives of this study are to (1) develop supplementary reading materials using Contextual Teaching and Learning Approach for students of SMA SahabatQu and (2) describe the efficacy of the supplementary reading materials. This research belongs to Educational Research and Development (R&D) using a simplified six steps of (Gall, Gall, & Borg, 2003) model. In general, the result of the research shows that the developed English reading module is beneficial, useful and appropriate to be used in improving reading skills of X graders of Senior High School Sahabatqu. After the module was tested, the efficacy of the developed product helped the students to achieve students’ need, optimize learning independently, learning by team, broaden knowledge and improve reading skills. Furthermore, the contextual English reading module provides additional learning resources for students. The necessities of the teaching and learning English is to improve students' English skills so that they gain good in reading and understanding text and they can learn independently. They can understand WH-questions that is important in learning reading. The efficacy of this product helps students to improve their reading skill especially to understand the topic, the generic structure, the main idea, the grammar and the vocabulary used in the text.
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Rudian, Rudian, and Imam Ghozali. "Developing supplementary English reading module for tenth-grader of senior high school SahabatQu Yogyakarta." Journal of English Language and Pedagogy 4, no. 1 (June 10, 2021): 48–59. http://dx.doi.org/10.36597/jelp.v4i1.11021.
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The objectives of this study are to (1) develop supplementary reading materials using Contextual Teaching and Learning Approach for students of SMA SahabatQu and (2) describe the efficacy of the supplementary reading materials. This research belongs to Educational Research and Development (R&D) using a simplified six steps of (Gall, Gall, & Borg, 2003) model. In general, the result of the research shows that the developed English reading module is beneficial, useful and appropriate to be used in improving reading skills of X graders of Senior High School Sahabatqu. After the module was tested, the efficacy of the developed product helped the students to achieve students’ need, optimize learning independently, learning by team, broaden knowledge and improve reading skills. Furthermore, the contextual English reading module provides additional learning resources for students. The necessities of the teaching and learning English is to improve students' English skills so that they gain good in reading and understanding text and they can learn independently. They can understand WH-questions that is important in learning reading. The efficacy of this product helps students to improve their reading skill especially to understand the topic, the generic structure, the main idea, the grammar and the vocabulary used in the text.
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Simón, P., J. Hällström, and A. Bergman. "Supplementary comparison for the traceability in high voltage capacitance and dissipation factor measurements (EURAMET.EM-S34)." Metrologia 59, no. 1A (January 1, 2022): 01009. http://dx.doi.org/10.1088/0026-1394/59/1a/01009.
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Main text The intercomparison consisted of calibrating the capacitance and loss factor (tan δ) of a set of reference capacitors at different voltage levels, including high voltage up to 200 kV, for frequencies between 50 Hz and 1kHz in low voltage measurements and 50 Hz in high voltage measurements. The travelling standards consisted of a set of four reference capacitors (TRC) with fixed input and grounding leads and the corresponding connection cables of the following rated characteristics: * System 1: 100 pF and rated voltage of 200 kV. * System 2: 100 pF and rated voltage of 700 V. * System 3: 500 nF and rated voltage of 10 V. * System 4: 5000 nF and rated voltage of 10 V. The coordinating laboratory was LCOE (Spain) and the participating institutes were LNE (France), VTT MIKES (Finland), RISE (Sweden), TÜBITAK UME (Türkiye), PTB (Germany) and LCOE (Spain). Participants used their best measurement procedures and setups in order to achieve their best calibration capabilities. Some of the institutes did not perform all the measurements, therefore comparison reference values are based sometimes in the results of only 4 institutes. Not all the laboratories measured at the same ambient temperature; to prevent this inconvenience and to be able to compare results, all capacitance values were corrected at 23 °C. The long drift of the high voltage capacitor of system 1, probably due to some small SF6 leakage, was also considered to calculate the CRV of each institute. Very good agreement between institutes is obtained for high voltage capacitance measurements (high voltage capacitance coefficient determination) and for low or high voltage dissipation factor measurements. Only a few low voltage measurements of capacitance are considered not compatible. Undertaking the work collaboratively through EURAMET proved to be an excellent tool to compare calibration and measurement capabilities of NMI and DI, as well as an opportunity for several institutes to improve their CMCs. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database https://www.bipm.org/kcdb/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
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Bangi, Josephat Obwoge, Mark Seidel, David Kimetto, Rolf Kumme, Henry Rotich, and Dirk Röske. "Report on the AFRIMETS.M. F-S1 supplementary force comparison for 10 kN and 100 kN." Metrologia 59, no. 1A (December 13, 2021): 07002. http://dx.doi.org/10.1088/0026-1394/59/1a/07002.
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Main text This bilateral comparison of Force Standard Machines (FSM) named AFRIMETS.M. F-S1 was carried out in the force range from 1 kN to 100 kN between Physikalisch-Technische Bundesanstalt (PTB) of Germany as the pilot laboratory and Kenya Bureau of Standards (KEBS) of Kenya as the participant laboratory. KEBS had already participated in the APMP.M. F-K2 key comparison where measurements were made only at 50 kN and 100 kN force steps. Therefore, this bilateral comparison was planned to thoroughly compare the KEBS FSM and the PTB Deadweight Machines in wider force steps than those of the APMP.M. F-K2 key comparison and thus it had no corresponding key-comparisons values to be linked to at that time. PTB provided two force transducers for the supplementary comparison with 10 kN and 100 kN nominal capacities. The comparison method called "DKD" procedure was used. This procedure has already been used in several comparisons in Germany and other countries. The purpose to this comparison is to give support to the uncertainty claims for KEBS and will be used to determine the Calibration and Measurement Capability (CMC). In addition, this comparison will provide metrological proof of the application for a CMC entry in the BIPM Key Comparison Database (KCDB). This report describes the scheme and results of the comparison. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database https://www.bipm.org/kcdb/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
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Wilkinson, D. H. "Exact geometrical realization of the Cabibbo–Kobayashi–Maskawa matrix: The catamorphy of quark–lepton families." Canadian Journal of Physics 69, no. 12 (December 1, 1991): 1459–70. http://dx.doi.org/10.1139/p91-217.
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It is suggested that the number of quark–lepton families is three as the result of a catamorphy; this is illustrated by a geometrical representation that limits the number of families to three, that most naturally generates 15 quark–lepton fields per family, and that exactly realizes the Cabibbo–Kobayashi–Maskawa matrix. The geometrical representation uniquely requires a 1:λ:λ2:λ3 hierarchy for the weak quark–quark linkages and, together with a supplementary Ansatz that derives from the geometrical representation, entrains CP violation in the [Formula: see text]-system and yields mt = 123 ± 65 GeV/c2 from an analysis of Cabibbo–Kobayashi–Maskawa phenomenology.
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Zhang, Henry B., Minji Kim, Jeffrey H. Chuang, and Yijun Ruan. "pyBedGraph: a python package for fast operations on 1D genomic signal tracks." Bioinformatics 36, no. 10 (February 11, 2020): 3234–35. http://dx.doi.org/10.1093/bioinformatics/btaa061.
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Abstract Motivation Modern genomic research is driven by next-generation sequencing experiments such as ChIP-seq and ChIA-PET that generate coverage files for transcription factor binding, as well as DHS and ATAC-seq that yield coverage files for chromatin accessibility. Such files are in a bedGraph text format or a bigWig binary format. Obtaining summary statistics in a given region is a fundamental task in analyzing protein binding intensity or chromatin accessibility. However, the existing Python package for operating on coverage files is not optimized for speed. Results We developed pyBedGraph, a Python package to quickly obtain summary statistics for a given interval in a bedGraph or a bigWig file. When tested on 12 ChIP-seq, ATAC-seq, RNA-seq and ChIA-PET datasets, pyBedGraph is on average 260 times faster than the existing program pyBigWig. On average, pyBedGraph can look up the exact mean signal of 1 million regions in ∼0.26 s and can compute their approximate means in <0.12 s on a conventional laptop. Availability and implementation pyBedGraph is publicly available at https://github.com/TheJacksonLaboratory/pyBedGraph under the MIT license. Supplementary information Supplementary data are available at Bioinformatics online.
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Aulia, Garin Akbar, Syahnan Daulay, and Malan Lubis. "THE DEVELOPMENT OF INTERACTIVE MULTIMEDIA WRITING EXPOSITIONAL TEXT BY IMPLEMENTING PROJECT BASED LEARNING IN STUDENT OF MTSN 1 MEDAN." Sensei International Journal of Education and Linguistic 1, no. 1 (April 5, 2021): 107–29. http://dx.doi.org/10.53768/sijel.v1i1.11.
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This study aims to determine the result of the development of interactive multimedia writing expositional text in Students MTsN 1 Medan. The media being developed is in the form of interactive multimedia. This type of research is development research based on the 4-D development model. The trial subjects consisting of design experts, material experts, Indonesian language teachers, and class VIII students of MTsN 1 Medan. The results showed that (1) the validation of the material experts included the eligibility of the content of 88.0% in the good category, the feasibility of the presentation of the learning module in 93.7% of the very good category, 95.8% of the interactive multimedia aspects of the very good category, 92 aspects of language assessment, 5% very good category, and project based learning aspects 83.3% good category (2) design expert validation includes initial design 89.2% with good category, content design 83.9% good category, media typography 83.3 good category, and illustration 87.5% good category. (3) the limited trial obtained a score of 82.79% with good criteria (4) The extended trial obtained a score of 80.04% in good category. Results of learning to produce a text exposition s Before the use of interactive multimedia to the model of project-based learning at 62 , 9 while the learning outcomes produced expositional texts using interactive multimedia with project based learning models gained 80.8. The difference obtained was 18 from before and after using digital media with the application of project based learning . This study have the implication that media is being developed will practically contribute especially in the implementation of the learning process for teachers as supplementary teaching materials to ease the burden on the material being taught to be independent and classical. Furthermore, students can improve the quality of learning, especially in expositional writing text activities with the content of learning interactive multimedia in it with project based learning model . Related to activities of working together and motivating each other to complete an expositional text.
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IORIO, L. "CONSTRAINING THE PREFERRED-FRAME α1, α2 PARAMETERS FROM SOLAR SYSTEM PLANETARY PRECESSIONS." International Journal of Modern Physics D 23, no. 01 (January 2014): 1450006. http://dx.doi.org/10.1142/s0218271814500060.
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Analytical expressions for the orbital precessions affecting the relative motion of the components of a local binary system induced by Lorentz-violating Preferred Frame Effects (PFE) are explicitly computed in terms of the Parametrized Post-Newtonian (PPN) parameters α1, α2. Preliminary constraints on α1, α2 are inferred from the latest determinations of the observationally admitted ranges [Formula: see text] for any anomalous Solar System planetary perihelion precessions. Other bounds existing in the literature are critically reviewed, with particular emphasis on the constraint [Formula: see text] based on an interpretation of the current close alignment of the Sun's equator with the invariable plane of the Solar System in terms of the action of a α2-induced torque throughout the entire Solar System's existence. Taken individually, the supplementary precessions [Formula: see text] of Earth and Mercury, recently determined with the INPOP10a ephemerides without modeling PFE, yield α1 = (0.8±4) × 10-6 and α2 = (4±6) × 10-6, respectively. A linear combination of the supplementary perihelion precessions of all the inner planets of the Solar System, able to remove the a priori bias of unmodeled/mismodeled standard effects such as the general relativistic Lense–Thirring precessions and the classical rates due to the Sun's oblateness J2, allows to infer α1 = (-1 ± 6) × 10-6, α2 = (-0.9 ± 3.5) × 10-5. Such figures are obtained by assuming that the ranges of values for the anomalous perihelion precessions are entirely due to the unmodeled effects of α1 and α2. Our bounds should be improved in the near-mid future with the MESSENGER and, especially, BepiColombo spacecrafts. Nonetheless, it is worthwhile noticing that our constraints are close to those predicted for BepiColombo in two independent studies. In further dedicated planetary analyses, PFE may be explicitly modeled to estimate α1, α2 simultaneously with the other PPN parameters as well.
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Cho, Ji-Youn. "Roles and Functions of the Korean Bible Society’s Journal of Biblical Text Research in Bible Translation Projects." Bible Translator 72, no. 1 (April 2021): 19–30. http://dx.doi.org/10.1177/2051677020983523.
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This article reviews various works in progress relating to the Journal of Biblical Text Research ( JBTR), which is published biannually by the Institute for Biblical Text Research (IBTR) of the Korean Bible Society (KBS), and proposes possible future roles and functions of JBTR in Bible translation projects. Since 1997, fifty volumes including three supplementary volumes have been published by JBTR, comprising a total of 611 articles. In reviewing these publications, this article specifically focuses on: (1) the initial roles and functions of JBTR; (2) the Korean Translation Workshops (KTW) 2003–2009 and the publications of JBTR; (3) JBTR for Korean Bible translation projects; (4) the influence of The Bible Translator ( TBT) on JBTR; and (5) the future roles and functions of JBTR in Bible translation projects. The article demonstrates how journals have contributed and can continue to contribute to Bible translation projects in Bible societies in cooperation with the United Bible Societies fellowship. In addition, further possible projects that the journal can meaningfully undertake in order to broaden its ministry and contribution will be discussed.
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Hayduk, Leslie. "Review essay on Rex B. Kline’s Principles and Practice of Structural Equation Modeling: Encouraging a fifth edition." Canadian Studies in Population 45, no. 3-4 (August 30, 2018): 154. http://dx.doi.org/10.25336/csp29397.
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Principles and Practice of Structural Equation Modeling, 4th editionRex B. KlineNew York: The Guilford Press 2016ISBN 978-1-4625-2334-4Softcover, US$65, 534 pp.Kline’s fourth edition is reasonably strong but improvable. The text aims to introduce newcomers to fundamental structural equation modeling (SEM) principles, but tends to confuse “Principles” with “Rules.” Rules having insufficient grounding in principles leave readers ill-prepared for understanding and responding to changes in previously traditional “rules”—such as those concerning model testing, and latents having single indicators. SEM’s foundations would be clearer if Kline began by presenting structural equation models as striving to represent causal effects—a commitment that differentiates structural equation models from regression and encourages model testing. I begin this review by summarizing the covariance/correlation implications of three simple causal structures, which pinpoints multiple text improvements and underpins the discussions of measurement and model testing that follow. Causal structuring also grounds my later comments regarding modelling means/intercepts and interactions. A file of Supplementary Sections expands on several points and lists multiple editorial corrections you might pencil into your copy of Kline’s text.
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Wilmsen, Edwin N. "Supplementary Notes on Charles John Andersson's Journey to the Okavango River." History in Africa 33 (2006): 513–21. http://dx.doi.org/10.1353/hia.2006.0024.
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Recently in this journal (Wilmsen 2003:360-375), I delineated Charles John Andersson's route to the Okavango River based on entries in his diaries and an overlooked map of the route published by Thomas Baines in 1866. noted there that, while the place, Okambombo, where Andersson first stood on the banks of the Okavango was correctly plotted on Baines' map, its geographical coordinates were given only approximately. I also noted that Andersson did not bring along his astronomical instruments on his first excursion to the river, and assumed therefore that no coordinates for the place were obtained. However, in the course of my preparation of Andersson's papers for publication, I have since worked through the 116 unnumbered pages of geographical calculations recorded in volume 10 of the papers and found latitude observations for several points along the route, including Ombongo and Okambombo; his calculations for these latter two places are shown in Figure 1.Andersson left the river on 29 March 1859 and returned to it on 29 April (CJAP-3.3:169); on 4 May the correct latitude, 17°46′08″S, was determined by astronomical observation. About this, Andersson (CJAP-3.3:172) wrote, “[o]btained a latitude. Between Ombongo & this place (Okambombo) I am only out a mile in latitude.” The latitude for Ombongo was obtained just before this, on 16 April on his way back to the river (CJAP-3.3:165). On Baines' map this latitude is given as 17°37′53″S, but as can be seen, this is just one of Andersson's interim reckonings before the “True Latd 17°39′38″” is calculated (figure 1). Baines (1866:217) gave approximate coordinates for Okambombo in his text, writing “17°30′S. lat. and longitude about 19°E,” but the correct coordinates (17°46′08″S about 18°55′E) are plotted on the map. Both discrepancies are due to the fact that the published map was redrawn by Royal Geographical Society cartographers, who copied one that Andersson made in Cape Town at Galton's urging (GP-UCL 1866) based on “upwards of three thousand prismatic compass triangulations and astronomical observations of latitudes” (found in volume 10), while Baines copied from the letter Andersson wrote from Okambombo to Dr. Norton Shaw, secretary of the Society.
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McEwen, M. R., P. H. G. Sharpe, I. M. Pazos, A. Miller, E. Pawlak, S. Ninlaphruk, Zhang Y, and C. Kessler. "Supplementary comparison CCRI(I)-S3 of standards for absorbed dose to water in 60Co gamma radiation at radiation processing dose levels." Metrologia 59, no. 1A (January 1, 2022): 06012. http://dx.doi.org/10.1088/0026-1394/59/1a/06012.
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Main text A supplementary comparison of standards for absorbed dose to water in 60Co fields used for calibrations at radiation processing dose levels has been completed. Alanine dosimeters from the NIST and the NPL were used as transfer dosimeters and all participant irradiations were carried out in self-shielded irradiators. Irradiations were also carried out at the BIPM to allow direct comparison of dose ratios with the Key Comparison BIPM.RI(I)-K4. No significant difference was seen between the dose ratios obtained using the NPL and NIST alanine systems, no significant impact of mailing on dosimeter response was noted, and the adopted protocol limited any dose rate effects to the level of Type A uncertainties. The national standards of the participants are in agreement within the standard uncertainties, which are in the range from 1 to 2 parts in 102. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database https://www.bipm.org/kcdb/. The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
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West, John B. "The 1988 Stevenson Memorial Lecture. Physiological responses to severe hypoxia in man." Canadian Journal of Physiology and Pharmacology 67, no. 3 (March 1, 1989): 173–78. http://dx.doi.org/10.1139/y89-030.
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Recent measurements at extreme altitude and in low pressure chamber simulations have clarified the human responses to extreme hypoxia. Man can only tolerate the severe oxygen deprivation of great altitudes by an enormous increase in ventilation which has the advantage of defending the alveolar [Formula: see text] against the reduced inspired [Formula: see text]. Nevertheless the arterial [Formula: see text] on the Everest summit is less than 30 Torr (1 Torr = 133.3 Pa). An interesting consequence of the hyperventilation is that the respiratory alkalosis greatly increases the oxygen affinity of the hemoglobin and assists in oxygen loading by the pulmonary capillary. The severe hypoxemia impairs the function of many organ systems including the central nervous system, and there is evidence of residual impairment of memory and manipulative skill in climbers returning from great altitudes. At the altitude of Mt. Everest, maximal oxygen uptake is reduced to 20–25% of its sea level value, and it is exquisitely sensitive to barometric pressure. It is likely that the seasonal variation of barometric pressure affects the ability of man to reach the summit without supplementary oxygen.Key words: high altitude, hyperventilation, respiratory alkalosis, CNS impairment, barometric pressure.
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Sixto-Costoya, Andrea, Rafael Aleixandre-Benavent, Rut Lucas-Domínguez, and Antonio Vidal-Infer. "The Emergency Medicine Facing the Challenge of Open Science." Data 5, no. 2 (March 25, 2020): 28. http://dx.doi.org/10.3390/data5020028.
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(1) Background: The availability of research datasets can strengthen and facilitate research processes. This is specifically relevant in the emergency medicine field due to the importance of providing immediate care in critical situations as the very current Coronavirus (COVID-19) Pandemic is showing to the scientific community. This work aims to show which Emergency Medicine journals indexed in Journal Citation Reports (JCR) currently meet data sharing criteria. (2) Methods: This study analyzes the editorial policies regarding the data deposit of the journals in the emergency medicine category of the JCR and evaluates the Supplementary material of the articles published in these journals that have been deposited in the PubMed Central repository. (3) Results: It has been observed that 19 out of the 24 journals contained in the emergency medicine category of Journal Citation Reports are also located in PubMed Central (PMC), yielding a total of 5983 articles. Out of these, only 9.4% of the articles contain supplemental material. Although second quartile journals of JCR emergency medicine category have quantitatively more articles in PMC, the main journals involved in the deposit of supplemental material belong to the first quartile, of which the most used format in the articles is pdf, followed by text documents. (4) Conclusion: This study reveals that data sharing remains an incipient practice in the emergency medicine field, as there are still barriers between researchers to participate in data sharing. Therefore, it is necessary to promote dynamics to improve this practice both qualitatively (the quality and format of datasets) and quantitatively (the quantity of datasets in absolute terms) in research.
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Tyson, Alan. "Some Problems in the Text of Le nozze di Figaro: Did Mozart Have a Hand in Them?" Journal of the Royal Musical Association 112, no. 1 (1987): 99–131. http://dx.doi.org/10.1093/jrma/112.1.99.
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A few puzzling features in the text of Figaro have been discussed for a very long time within the vast literature on this opera. Nevertheless there is little in the libretto that Lorenzo Da Ponte based on Beaumarchais's revolutionary play La Folle Journée, ou Le Mariage de Figaro, and in the music that Mozart then provided for it, which is really problematical. After all, almost the entirety of Mozart's long autograph score has come down to us, even though today Acts 1 and 2 are divided geographically from Acts 3 and 4 - the first two acts being in the Deutsche Staatsbibliothek, Berlin (DDR), and the last two (which left the Berlin library in World War II) being at present in the Biblioteka Jagiellońska at Kraków in Poland. (The whole autograph is fortunately accessible today.) It would seem that the only portions that have not come down to us in Mozart's handwriting are a couple of passages for recitative, and some of the supplementary wind parts for the last act's finale; we have these merely in the handwriting of copyists, included inter alia in scores made for early performances, or for sale in Vienna and other cities. Several of these copyists' scores will shortly be discussed here.
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Noto, Geyereni Maretika, Sofendi Sofendi, Rita Indera Wati, Hartono Hartono, and Ratu Ilma Indra Putri. "Climate Change Exposition Reading Materials for Senior High School Textbook: Students’ Needs Analysis." AL-ISHLAH: Jurnal Pendidikan 14, no. 2 (June 16, 2022): 2429–36. http://dx.doi.org/10.35445/alishlah.v14i2.1030.
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This research intends to dig out the Senior High School students' needs in English reading materials development based on climate change material revised by students', and teachers' views. The data were obtained by applying a questionnaire and semi-structured interviews. The data are described both quantitatively and qualitatively. The outcomes of the need analysis represent that: 1) English is important to students' future careers, (2) students’ English proficiency is at the beginner level, 3) students still get some hardship in writing skills, 4) the type of text needed is an exposition text, 5) it has connected between English reading materials and the content subject materials, 6) students still run short of awareness about climate change material, 7) There is still the limitation of climate change as the English reading materials, 8) two major causes for connecting climate change material into educational materials are to increase the awareness of students. As a consequence of the needs, it is important to develop supplementary exposition reading materials by connecting climate change which fit the students’ English proficiency and can help out their study program.
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Deng, Xue-Mei, and Yi Xie. "New upper limits of a braneworld model with recent Solar System tests." Modern Physics Letters A 31, no. 05 (February 5, 2016): 1650021. http://dx.doi.org/10.1142/s0217732316500218.
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As an extension of previous works on classical tests of a braneworld model which is called as the Dadhich, Maartens, Papadopoulos and Rezania (DMPR) solution, and as an attempt to find more stringent constraints on this model, we investigate its effects on physical experiments and astronomical observations conducted in the Solar System by modeling new observable effects and adopting new datasets. First, we investigate gravitational time delay at inferior conjunction (IC) caused by the braneworld model, which was not considered in previous works, because these measurements are not affected by the solar corona noise. Second, the Cassini superior conjunction (SC) experiment is, for the first time, used to test the DMPR model. Third, compared to previous works, we refine the model, which confronts the perihelion shift induced by the braneworld model with modern Solar System ephemerides INPOP10a (IMCCE, France) and EPM2011 (IAA RAS, Russia). The correction of DMPR solution to Einstein’s general relativity (GR) in the four-dimensional spacetime can be characterized by a constant bulk “tidal charge” parameter [Formula: see text], which is confined in the present work. We find that time delay experiment at IC is independent of [Formula: see text] and not suitable for testing the braneworld model. However, the Cassini SC experiment and modern Solar System ephemerides can give better upper bounds on [Formula: see text]: (1) [Formula: see text] by Cassini, and (2) [Formula: see text] based on the supplementary advances of the perihelia provided by INPOP10a and [Formula: see text] based on the ones of EPM2011. The latter upper bounds are improved to be tighter than the ones of previous works by at least two orders of magnitude. Besides, the stronger constraints on the brane tension are given by the modern ephemerides, which are [Formula: see text] for INPOP10a and [Formula: see text] for EPM2011. These improved upper bounds mean that the Solar System tests can serve as a good testbed for high dimensional theories.
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Joppich, Markus, Christian Weber, and Ralf Zimmer. "Using Context-Sensitive Text Mining to Identify miRNAs in Different Stages of Atherosclerosis." Thrombosis and Haemostasis 119, no. 08 (August 2019): 1247–64. http://dx.doi.org/10.1055/s-0039-1693165.
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790 human and mouse micro-RNAs (miRNAs) are involved in diseases. More than 26,428 miRNA–gene interactions are annotated in humans and mice. Most of these interactions are posttranscriptional regulations: miRNAs bind to the messenger RNAs (mRNAs) of genes and induce their degradation, thereby reducing the gene expression of target genes. For atherosclerosis, 667 miRNA–gene interactions for 124 miRNAs and 343 genes have been identified and described in numerous publications. Some interactions were observed through high-throughput experiments, others were predicted using bioinformatic methods, and some were determined by targeted experiments. Several reviews collect knowledge on miRNA–gene interactions in (specific aspects of) atherosclerosis.Here, we use our bioinformatics resource (atheMir) to give an overview of miRNA–gene interactions in the context of atherosclerosis. The interactions are based on public databases and context-based text mining of 28 million PubMed abstracts. The miRNA–gene interactions are obtained from more than 10,000 publications, of which more than 1,000 are in a cardiovascular disease context (266 in atherosclerosis). We discuss interesting miRNA–gene interactions in atherosclerosis, grouped by specific processes in different cell types and six phases of atherosclerotic progression. All evidence is referenced and easily accessible: Relevant interactions are provided by atheMir as supplementary tables for further evaluation and, for example, for the subsequent data analysis of high-throughput measurements as well as for the generation and validation of hypotheses. The atheMir approach has several advantages: (1) the evidence is easily accessible, (2) regulatory interactions are uniformly available for subsequent high-throughput data analysis, and (3) the resource can incrementally be updated with new findings.
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Simón, P., J. Hällström, and A. Bergman. "Supplementary comparison for the traceability of AC high voltage reference measuring systems up to 200 kV (EURAMET.EM-S33)." Metrologia 59, no. 1A (January 1, 2022): 01008. http://dx.doi.org/10.1088/0026-1394/59/1a/01008.
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Main text The intercomparison consisted of calibrating a High Voltage Travelling Reference Measuring System, TRMS, using peak and rms voltage values, at the frequency of 50 Hz and with voltages of 750 V, 1 kV, 40 kV, 80 kV, 120 kV, 160 kV and 200 kV. The TRMS consisted of a capacitive divider with fixed input and grounding leads, a coaxial cable, a HP 3458A digital multimeter and a computer with a printer. The TRMS had two ranges, 20 kV and 200 kV, depending on the low voltage arm connected to the high voltage capacitor. The TRMS included the low voltage digital multimeter, in such a way that the measuring error of high voltage TRMS should be measured to determine the scale factor of the high voltage divider. Intercomparison results are expressed as the scale factor of the travelling high voltage capacitive divider, the scale factor is dimensionless. Complementary low voltage measurements were also performed to check how the peak voltage is evaluated when harmonics or distortion are superimposed to sinusoidal waveforms. To evaluate this performance an arbitrary waveform generator was included among the travelling devices in such a way that it was possible to compare the peak voltage measured by the TRMS using the provided digital multimeter and the specific intercomparison software and the peak voltage measured by each participant. The coordinating laboratory was LCOE (Spain) and the participating institutes were LNE (France), VTT MIKES (Finland), RISE (Sweden), TÜBITAK UME (Türkiye), PTB (Germany), BIM (Bulgaria), INRiM (Italy), VSL (Netherlands), VNIMS (Russia) and LCOE (Spain). Results of the comparison proved the calibration and measurement capabilities, CMCs, of the participants in the field of high voltage AC measurement, especially when performing peak hv measurements up to 200 kV with expanded uncertainties in the range of 40 mV/V to 80 mV/V. The discrepancy between the results of the two labs claiming the lowest uncertainties, PTB and VTT, was on some measurements significantly larger than the respective uncertainties. One of these labs redesigned its measuring system and a subsequent bilateral comparison arranged between PTB and VTT solved the discrepancy. Undertaking the work collaboratively through EURAMET proved to be an excellent tool to compare calibration and measurement capabilities of NMI and DI, as well as an opportunity for several institutes to improve their CMCs. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database https://www.bipm.org/kcdb/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
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Che, Xiaoyin, Haojin Yang, and Christoph Meinel. "The Automated Generation and Further Application of Tree-Structure Outline for Lecture Videos with Synchronized Slides." International Journal of Technology and Educational Marketing 4, no. 1 (January 2014): 34–50. http://dx.doi.org/10.4018/ijtem.2014010103.
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In this paper, the authors illustrate their motivation and method in the automated generation of tree-structure outline for lecture videos with supplementary synchronized slides, and then propose a further application, lecture video segmentation by slide-group-change event, based on the outline previously generated. Starting with OCR (Optical Character Recognition) result, with an approximate accuracy of 90%, the authors attempt to reconstruct the text system of each slide into an up-to-3-level content tree, and then explore logical relations between slides in order to set them hierarchical. A final up-to-6-level outline will be achieved after removing all the redundancy. And the hierarchy of the slides, which is saved in the outline, will largely simplify the additional segmentation process. Evaluation result shows that, the final outline generated based on the test dataset retains about only 1/4 of the original texts from all slides and is organized well, with a high accuracy of 85% at slide title level. And the majority of the segments the authors' get are logically reasonable, while the average length of them is about 5~15 minutes.
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Thumbeck, Sarah-Maria, Philipp Schmid, Sophie Chesneau, and Frank Domahs. "Efficacy of a strategy-based intervention on text-level reading comprehension in persons with aphasia: a study protocol for a repeated measures study." BMJ Open 11, no. 7 (July 2021): e048126. http://dx.doi.org/10.1136/bmjopen-2020-048126.
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IntroductionAt least 68% of persons with aphasia (PWA) experience reading difficulties. Even though strategy-based interventions are a promising treatment approach for text level reading comprehension deficits in PWA, empirical evidence for their efficacy remains rare. The primary objective of this study is the analysis of the efficacy of a strategy-based intervention on text-level reading comprehension and on reading activities in PWA.Methods and analysisIn a repeated measures trial, 24 PWA will first participate in a waiting period and then in a strategy-based intervention (14 face-to-face-sessions, 60 min each). We will apply two combinations of strategies to treat either the microstructure or the macrostructure, respectively. Participants will be randomly allocated to two parallel groups that will receive these combinations in interchanged sequences. Assessments will be implemented before and after each period as well as 3 and 6 months after the intervention. The primary outcome measure is text-level reading comprehension measured with a German version of the Test de Compréhension de Textes (TCT-D) and represented by the score TCT-D Total . A non-blinded and a blinded rater will evaluate the primary outcome measure. Secondary outcome measures will address specific reading functions, reading activities and cognitive functions. The sample size was determined with an a priori power analysis. For statistical analysis, we will use contrast analyses within repeated measures analysis of variance models. We expect significant improvements in primary and secondary outcome measures during the intervention as compared with changes during the waiting period.Ethics and disseminationThis study was approved by the ethics committee of Deutscher Bundesverband für akademische Sprachtherapie und Logopädie (20–10074-KA-MunmErw+Ko). Results and relevant data will be disseminated in peer-reviewed journals, at conferences and on the Open Science Framework.Trial registration numberDRKS00021411 (see Supplementary Table 1).
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Sato, Koji, Reo Kimura, and Shoji Ohtomo. "Typology of Learning Contents in “Supplementary Textbook for Disaster Prevention Education” – What Are Teachers in the Areas Affected by the Great Hanshin-Awaji Earthquake in 1995, and the Great East Japan Earthquake in 2011, Striving to Teach Students in Junior High School? –." Journal of Disaster Research 16, no. 4 (June 1, 2021): 794–812. http://dx.doi.org/10.20965/jdr.2021.p0794.
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A supplementary textbook for disaster prevention education was analyzed for understanding the content educators wish to include in disaster prevention curriculums. The text was a condensed textbook – edited by schoolteachers and boards of education in the local governments – from wide areas with a population of one million who were severely affected by the damage and deaths caused by the Great Hanshin-Awaji and the Great East Japan Earthquakes. The targets for analysis were supplementary textbooks for students in junior high schools, published by the five boards of education in Miyagi, Sendai, Iwate, Hyogo, and Kobe. 147 subjects of five supplementary textbooks for disaster prevention education were evaluated as to their applicability to 46 evaluation items. The average of the evaluation items was 11.59 (SD = 2.92). Numerous “Records” (111 subjects, 75.5%) and “Images” (109 subjects, 74.1%), resulted from each evaluation. A remarkable majority of disaster types included “Earthquake disasters” (108 subjects, 73.5%) and “Tsunami disasters” (85 subjects, 57.8%). “Related Fields,” “Social studies” (30 subjects, 20.4%), and “Science” (29 subjects, 19.7%) were the most common subjects. In “Related Fields,” “Special activities” included the highest subjects (59 subjects, 40.1%), after “Ethics,” which included 56 subjects (38.1%). “Writer and persons involved” and “Student who writes compositions and is involved as a learner” included 72 subjects (49.0%). Subsequently, there were “Local residents,” (52 subjects, 35.4%), “Researchers and experts” (36 subjects, 24.5%), and “Unaffected persons” (35 subjects, 23.8%), which included volunteers. Regarding “Type of disaster prevention education,” learning activities for “Prepare for disasters” included the most subjects at 92 (62.6%). Subsequently, learning activities to “Enrich the mind (love for family and community, compassion, the importance of life,)” by raising students’ included 60 subjects (40.8%). Regarding “Qualities and abilities expected to be acquired,” “Knowledge” showed the highest 91 subjects (61.9%). Next was “Self-awareness” (64 subjects, 43.5%), “Social participation/community contribution” (48 subjects, 32.7%), and “Kindness to disaster-affected people” (47 subjects, 32.0%). Moreover, cluster analysis (ward method) was performed using a data set of the subject evaluation of the supplementary textbooks. The analysis with subjects presented six types: “Life-saving measures,” “Fortifying town,” “Measures required for disaster survival,” “Awareness of joining local community,” “Disaster comradery,” and “Living with family and community.” All the five supplementary textbooks featured those six types. More than half of the subjects were featured content regarding student emotions. The first three types were combined and understood as “Countermeasures” with “Knowledge.” In addition, the latter three types were combined and understood as subjects to teach the “Will to live together,” with a relation such as that of ethics and emotional learning. When the same data set was subjected to cluster analysis (ward method) using the evaluation items, four types were obtained: “Knowledge to prepare for earthquake and tsunami disasters,” “Solidarity with family and residents,” “Emergency Response Judgement,” and “Knowledge and skills useful at disaster time.” The types correspond to the classification of the conceptual model of disaster prevention education conducted by Sato et al. [1]. Additionally, all types have corresponding qualities and abilities. The results led teachers to believe that disaster prevention education should be implemented, not simply as life-saving education, but also as instructions that promote the emotional growth of children while cultivating humanity.
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Feng, Yongzhi, Feng Tao, Libin Jiang, Dan Ni, Jun Zhang, Linxin Wu, Lin Shi, and Genhua Yu. "Secondary myelodysplastic syndrome identified via next-generation sequencing in non-small cell lung cancer patients." Journal of Clinical Oncology 38, no. 15_suppl (May 20, 2020): e19531-e19531. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e19531.
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e19531 Background: Chemotherapy and radiotherapy used in cancer treatment are associated with increased risk of secondary myelodysplastic syndrome (MDS). MDS is characterized with specific chromosomal abnormalities and genomic alterations in JAK2, KRAS, CBL, DNMT3A, TET2, IDH1/2, EVI1, RUNX1, GATA2, EZH2, ASXL1, SF3B1, U2AF1, SRSF2 and ZRSR2. Since next generation sequencing (NGS) techniques have been widely used for the detection of actionable genomic variation in solid tumor patients, analysis of NGS data for chromosomal abnormalities and gene mutations may be supplementary for diagnosis of secondary MDS. Methods: We retrospectively analyzed targeted NGS data of paired tumor and blood samples from patients with non-small cell lung cancer (NSCLC) for chromosomal abnormalities and gene mutations. Sequence panel covered whole exons of 381 genes associated with cancers. Sequence data were processed using a customized analysis pipeline designed to accurately detect multiple classes of genomic alterations in routine clinical specimens. All testing was done in a CLIA-certified, CAP-accredited laboratory. Clinical information of cases with chromosomal abnormalities was reviewed, including treatment for previous cancer, blood and bone marrow tests. Results: We found 4 cases carrying MDS associated chromosome abnormalities among 3523 NSCLC patients with the prevalence of0.1%. They were old (from 66 to 71 years old), and were more likely to be male (3 males and 1 females). All of 4 cases included common abnormalities associated with MDS like 5q-, 7q-, -7, +21. 3 cases had complex (≥3) abnormalities and 1 case had double abnormalities. Point mutations were identified in blood samples of 3 cases. Mutations in TP53 occurred in 3 cases, mutations in ASXL1, DNMT3A, FLT3 and CBL occurred in one case respectively. Among the 4 cases, 2 cases were confirmed as MDS by blood and bone marrow tests. Conclusions: We identified 4 MDS associated chromosomal abnormalities from 3523 NSCLC patients through analyzing NGS data. NGS techniques could serve as supplementary for diagnosis of secondary MDS. [Table: see text]
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Terashima, Masanori, Junki Mizusawa, Hiroshi Katayama, Yoshiaki Iwasaki, Yoshiyuki Kawashima, Takahiro Kinoshita, Souya Nunobe, et al. "Surrogate indicators of survival in patients who received neoadjuvant chemotherapy for type 4 and large type 3 gastric cancer in JCOG0501." Journal of Clinical Oncology 38, no. 4_suppl (February 1, 2020): 381. http://dx.doi.org/10.1200/jco.2020.38.4_suppl.381.
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381 Background: Pathological response rate (pRR) is a common endpoint for assessing the efficacy of neo-adjuvant chemotherapy (NAC) in patients with advanced gastric cancer (GC). We performed supplementary analysis to investigate if pRR can be a surrogate endpoint using data from JCOG0501. Methods: Patients with type 4 and large type 3 resectable GC were randomized either surgery plus adjuvant S-1 (arm A) or NAC (S-1 plus cisplatin) plus surgery plus S-1 (arm B) in JCOG0501. Histological type (sig vs non-sig) was evaluated using preoperative biopsy specimen. Cox proportional hazards model was utilized to assess the effects of covariates for overall survival (OS). Pathological response was defined as Grade1b-3 according to the Japanese Gastric Cancer Association grading. Results: Among 286 (147 in arm A and 139 in arm B) patients who underwent surgery, 132 patients with complete pathological data in arm B were evaluated. Macroscopic tumor response (PR) was observed in 47 patients (36%) and pathological response (Grade 0/1a/1b/2/3) was 15/40/30/44/3, respectively. As shown in the table, pathological response was significantly better OS after adjusting other factors (HR, 0.51 [95% CI 0.30-0.87], p = 0.014). Conclusions: pRR may be used as a surrogate endpoint for future clinical trials in type 4 and large type 3 GC. Clinical trial information: C000000279. [Table: see text]
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Boyko, Lyudmila B., Kristina S. Chugueva, and Alexandra K. Gulina. "Peritext of the Russian translation of William Hogarth’s Analysis of Beauty: a case study." Slovo.ru: Baltic accent 12, no. 1 (February 2021): 34–49. http://dx.doi.org/10.5922/10.5922/2225-5346-2021-1-2.
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Translation of philosophical texts is a special challenge because of specific philosophical idiom and conceptual complexity of the narrative. It is not surprising that such translations are often accompanied by commentaries where the translator steps out of the shadows to justify the translational decisions. This kind of supplementary text called the “translational peritext” is under study in this paper aiming to reveal the cognitive effort the translation process involves, and to explore the author-translator-reader relationship. The purpose of the article is to analyze paratextual elements in the translation of an essay on philosophical aesthetics in search of answers to three main questions: What does the translator choose to comment on, and why? What is specific about the role and function of translational peritext in philosophical artistic discourse? How do the commented translational decisions affect, if at all, the reader’s understanding of the author’s stance? The problem of revealing the translator’s agency, his/her motivations and decision-making is investigated on the basis of the essay Analysis of Beauty by the celebrated 18th century English artist William Hogarth — an influential philosophical treatise whose ideas have never lost their relevance. The paper starts with the brief account of the concept of paratext, its types and functions; it will then proceed to specificities of philosophical translation. In the main part of the article, the background information on the material under study precedes the analysis of the identified commented translational issues.
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Kusumawardani, Rheza, Riyadi Santosa, and Dewi Roschsantiningsih. "Explore the Use of Authentic Materials to Teach Reading for Junior High School." International Journal of Multicultural and Multireligious Understanding 5, no. 4 (May 6, 2018): 298. http://dx.doi.org/10.18415/ijmmu.v5i4.323.
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Authentic materials provide many advantages and promote something new, challenging, and interesting in teaching-learning process, which can build students’ motivation in English learning. This study aims to explore about the types of authentic material which are used in teaching reading and what kinds of reading activity can be implement by using authentic material. In this research, a case study was applied as the research method and the data were qualitative data. To collect the data, some techniques of data collection were used such as observing the classroom activity, conducting the interview to the subjects of the research, and analyzing the documents. Through the data analyziz, the researcher sumerized two points from this study: 1) The authentic materials used by the eighth grade teacher of Junior High School are texts obtained from the internet, printed story book, videos, and pictures; 2) The reading activities conducted by the eighth grade teacher of Junior High School through the use of authentic materials as supplementary materials are reading aloud, walking gallery, filling in blanks, rearranging jumbled paragraphs, doing cloze tasks, having short answer tasks, conducting information transfer, having text analysis, and doing some vocabulary ordering.
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Tseng, Jennifer, Darren S. Bryan, Elizabeth Poli, Manish Sharma, Blase N. Polite, and Kiran Turaga. "Representation of peritoneal metastases in published clinical trials of metastatic colorectal cancer." Journal of Clinical Oncology 35, no. 4_suppl (February 1, 2017): 725. http://dx.doi.org/10.1200/jco.2017.35.4_suppl.725.
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725 Background: Peritoneal metastases occur in 6-15% of patients with metastatic colorectal cancer. Non-invasive detection of peritoneal metastases is difficult given limitations in discrimination of cross sectional imaging. We hypothesized that patients with peritoneal metastases are underrepresented in clinical trials. Methods: Randomized controlled trials of systemic chemotherapy for metastatic colorectal cancer between 2003-16 were included after a PubMed search. Articles were restricted to those published in leading oncology journals and with ≥100 patients (total). Protocol designs were hand searched to identify whether clinical trials explicitly included or reported on patients with peritoneal metastases. Results: Of 72 clinical trials identified, 7 (10%) studies specifically reported inclusion of peritoneal disease (Table 1). Of 45,783 patients enrolled in all trials, 670 patients (1.5%) specifically had peritoneal metastases. Response for peritoneal disease was measured using Response Evaluation Criteria in Solid Tumors (RECIST) criteria in 6 (of 7, 86%) and modified World Health Organization (WHO) criteria in 1 but not reported in the final manuscript or supplementary material. Peritoneal specific outcomes were not reported in any study. No studies included metastatic colorectal cancer patients with peritoneal metastases alone. Conclusions: Patients with peritoneal metastases are underrepresented in published clinical trials. Specific efforts to include patients, measure burden of disease and response to therapy and report peritoneal specific outcomes are essential to draw generalizable inferences. [Table: see text]
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Mokoginta, Novita Sari, Hasanuddin Sartin T Miolo, and MOON H. OTOLUWA. "DEVELOPING SUPPLEMENTARY ENGLISH READING MATERIAL BASED ON CONTEXTUAL TEACHING AND LEARNING FOR NURSING STUDY PROGRAM (A study conducted at XI Grade Nursing Study Program in Public Vocational School 1 Bonepantai Indonesia)." International Journal of Education and Social Science Research 05, no. 03 (2022): 261–72. http://dx.doi.org/10.37500/ijessr.2022.5317.
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The objectives of this research are to discover the students need in reading skill and to develop English reading material based on contextual teaching and learning for nursing study program at SMK Negeri 1 Bonepantai. This research used Research and Development (R&D) by Borg and Fall (1983This study was conducted at students of XI grade nursing study program at SMK Negeri 1 Bonepantai Indonesia. Data were collected by using questionnaires, interview, and document. The needs assessment questionnaire was analyzed by using simple descriptive statistics. The book developed was validated by expert of content and expert of technology and design. Field testing for validation has been done to 14 students of Xi grade nursing study program. The findings indicated that (1) the students need to get an English learning in order to be able to get information through English reading text. (2) the learning need of the students is the learning material for reading of which topics are related to health based on their life context. (3) The English book was developed as the product of this research is appropriate based on the result of expert judgment, readability, and field testing validation. (4) the English book that was developed offered an influence on students’ skill in reading. Finally, it can be concluded that the English reading material based on contextual teaching and learning was appropriate and suitable the learning for XI grade nursing study program in vocational high school.
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Tyrpa, Anna. "Krystyna Pisarkowa – ta, która inspiruje." LingVaria 16, no. 2(32) (November 18, 2021): 203–13. http://dx.doi.org/10.12797/lv.16.2021.32.16.
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Krystyna Pisarkowa – The One Who Inspires
The article consists of three parts. In the first one: Krystyna Pisarkowa as a Supervisor, the author shares her memories from the times when she wrote the doctoral thesis supervised by Pisarkowa. In the second part: Krystyna Pisarkowa – the Author of an Article, the author discusses how the text by Pisarkowa entitled Semantic Connotation of Nationalities provided inspiration to fourteen authors of twenty-three monographs and one lexicon. Most of those scholars are experts in Polish language and linguists, but the thoughts included in Pisarkowa’s article also influenced two experts in Russian studies: one sociologist and one anthropologist of culture. Those books were published within 40 years (1980–2020). Five of them were published after the death of Krystyna Pisarkowa. This proves the power of her article’s influence. The third part of the article is entitled Supplement. It describes the history of the book by Ogden and Richards: The Meaning of Meaning. A Study of The Influence of Language upon Thought and of The Science of Symbolism with Supplementary Essays by B. Malinowski and F. G. Crookshank, which followed a strange route from London and reached Pisarkowa who used it while writing: Linguistics by Bronisław Malinowski, vol. 1: Bonds of Shared Language (2000).
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Ciezki, Jay P., Chandana A. Reddy, Michael A. Weller, Rahul D. Tendulkar, Kevin L. Stephans, James Ulchaker, Kenneth Angermeier, Steven C. Campbell, Andrew J. Stephenson, and Eric A. Klein. "The effect of androgen deprivation therapy on prostate cancer-specific mortality in high-risk prostate cancer: Patients treated with low dose-rate brachytherapy without supplementary external beam radiotherapy." Journal of Clinical Oncology 35, no. 6_suppl (February 20, 2017): e550-e550. http://dx.doi.org/10.1200/jco.2017.35.6_suppl.e550.
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e550 Background: Androgen deprivation therapy (ADT) is a mainstay accompaniment of external beam radiotherapy (EBRT) for treating high-risk prostate cancer (HPCaP). Both low dose-rate brachytherapy (LDR) as the sole method of radiotherapy and the need for ADT in conjunction with it are relatively unexplored with HRCaP. We present an inception cohort study of HRCaP patients treated with LDR alone with or without ADT. Methods: The study includes 515 patients with HRCaP according to NCCN guidelines. They were treated with I-125 LDR alone to a dose of 144 Gy with lateral, superior, and inferior margins of at least 5 mm (medin D90 = 149.39 Gy). The association of prostate cancer-specific mortality (PCSM) with pre-treatment variables was assessed with Fine and Gray regression with non-PCSM mortality treated as a competing event. PCSM rates were calculated using the cumulative incidence method. Results: The median age is 70 years. The median f/u is 48.9 months. Fifty-four percent were Gleason 7, 28% were Gleason 8, and 11% were Gleason 9. Fifty-three percent received ADT for a median duration of 6 months (range = 1-32 months). At 5 years, the PCSM rate was 1.2 % for LDR and 4.2% for LDR + ADT, and at 10 years, the PCSM rate for LDR was 3.3% and 4.2% for LDR + ADT (p = 0.34). Table 1 shows the association of pre-treatment factors with PCSM. Conclusions: ADT does not affect PCSM for HRCaP patients. Further studies should be done to explore if ADT is necessary with LDR for HRCaP. [Table: see text]
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Jiang, Di Maria, Bryan Wong, Joaquim Bellmunt, Thomas Powles, Alicia K. Morgans, David J. Vaughn, and Srikala S. Sridhar. "Improving quality of health-related quality of life (HRQOL) reporting in phase III randomized controlled trials (RCTs) of metastatic urothelial carcinoma (mUC)." Journal of Clinical Oncology 38, no. 6_suppl (February 20, 2020): 467. http://dx.doi.org/10.1200/jco.2020.38.6_suppl.467.
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467 Background: HRQOL data are increasingly used to guide patient care and health policy. However, their utility can be compromised by inadequate quality of HRQOL reporting (QHR). We aimed to systematically evaluate QHR in phase III RCTs of mUC. Methods: A comprehensive systematic review following PRISMA guidelines identified published manuscripts of phase III RCTs of mUC in English between 1985 - 2019. Supplementary material, references and companion publications were reviewed. QHR was quantified using: 1) 2013 CONSORT-PRO extension (CPE), and 2) 2003 Minimum Standard Checklist for Evaluating HRQOL Outcomes in Cancer Clinical Trials (MSC). Both scores range from 0-11, with higher scores indicating higher QHR. QHR is “probably robust” if MSC score is ≥8 and all 3 mandatory items (baseline compliance, missing data, and psychometric properties) are reported; “limited” if MSC score is 5-7; and “very limited” if MSC score is ≤4. Results: HRQOL data was collected in 7/21 (33%) mUC phase III RCTs. All reported HRQOL data as secondary/exploratory endpoints. Generic instruments included EORTC QLQ-C30 alone (n=3) or combined with EQ-5D (n=2)/McGill pain questionnaire (n=1). Disease-specific FACT-Bl was used in 1 RCT. Both checklists showed strong correlation (Spearman coefficient 0.94, p=0.001). QHR was often limited, however has improved in recent years (Table). No RCT stated HRQOL-specific hypotheses. Only 1 reported instrument validity and mode of administration. Few provided domain specific results (n=2) and statistical methods for handling missing data (n=3). Implications for clinical practice were only discussed in 3 RCTs. Conclusions: QHR has improved over time however many critical methodological deficiencies remain in mUC phase III RCTs. The use of standard checklists are encouraged to further enhance QHR and promote high quality HRQOL research. [Table: see text]
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Zelenin, Egor, Dmitry Bachmanov, Sofya Garipova, Vladimir Trifonov, and Andrey Kozhurin. "The Active Faults of Eurasia Database (AFEAD): the ontology and design behind the continental-scale dataset." Earth System Science Data 14, no. 10 (October 7, 2022): 4489–503. http://dx.doi.org/10.5194/essd-14-4489-2022.
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Abstract. Active faults are those faults on which movement is possible in the future. This draws particular attention to active faults in geodynamic studies and seismic hazard assessment. Here, we present a high-detail continental-scale geodatabase: The Active Faults of Eurasia Database (AFEAD). It comprises 48 205 objects stored in shapefile format with spatial detail sufficient for a 1 : 1 000 000 map scale. The fault sense, a rank of confidence in activity, a rank of slip rate, and a reference to source publications are provided for each database entry. Where possible, this information is supplemented by a fault name, fault zone name, abbreviated fault parameters (e.g., slip rate, age of the last motion, and total offset), and text information from the sources. The database was collected from 612 published sources, including regional maps, databases, and research papers. AFEAD facilitates a spatial search for local studies. It provides sufficient detail for planning a study of a particular fault system and guides deeper bibliographical investigations. This scenario is particularly significant for vast central and northern Asian areas, where most studies are available only in Russian and hard copy. Moreover, the database model provides the basis for regional- and continental-scale integrative studies based on geographic information systems (GISs). The database is available at https://doi.org/10.13140/RG.2.2.25509.58084 (Bachmanov et al., 2022) and via web map at http://neotec.ginras.ru/index/mapbox/database_map.html (last access: 5 May 2022). Database representations and supplementary data are hosted at http://neotec.ginras.ru/index/english/database_eng.html (last access: 5 May 2022).
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Nelson, David, Ian McGonagle, Christine Jackson, and Ros Kane. "What is known about the role of rural-urban residency in relation to self-management in people affected by cancer who have completed primary treatment? A scoping review." Supportive Care in Cancer 29, no. 1 (August 3, 2020): 67–78. http://dx.doi.org/10.1007/s00520-020-05645-0.
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Abstract Purpose Despite wide acknowledgement of differences in levels of support and health outcomes between urban and rural areas, there is a lack of research that explicitly examines these differences in relation to self-management in people affected by cancer following treatment. This scoping review aimed to map the existing literature that examines self-management in people affected by cancer who were post-treatment from rural and urban areas. Methods Arksey and O’Malley’s framework for conducting a scoping review was utilised. Keyword searches were performed in the following: Academic Search Complete, CINAHL, MEDLINE, PsycINFO, Scopus and Web of Science. Supplementary searching activities were also conducted. Results A total of 438 articles were initially retrieved and 249 duplicates removed leaving 192 articles that were screened by title, abstract and full text. Nine met the eligibility criteria and were included in the review. They were published from 2011 to 2018 and conducted in the USA (n = 6), Australia (n = 2) and Canada (n = 1). None of the studies offered insight into self-managing cancer within a rural-urban context in the UK. Studies used qualitative (n = 4), mixed methods (n = 4) and quantitative designs (n = 1). Conclusion If rural and urban populations define their health in different ways as some of the extant literature suggests, then efforts to support self-management in both populations will need to be better informed by robust evidence given the increasing focus on patient-centred care. It is important to consider if residency can be a predictor of as well as a barrier or facilitator to self-management.