Journal articles on the topic 'SUMO Targeted Ubiquitin Ligase'
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Sriramachandran, Annie M., and R. Jürgen Dohmen. "SUMO-targeted ubiquitin ligases." Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1843, no. 1 (January 2014): 75–85. http://dx.doi.org/10.1016/j.bbamcr.2013.08.022.
Full textPoulsen, Sara L., Rebecca K. Hansen, Sebastian A. Wagner, Loes van Cuijk, Gijsbert J. van Belle, Werner Streicher, Mats Wikström, et al. "RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response." Journal of Cell Biology 201, no. 6 (June 10, 2013): 797–807. http://dx.doi.org/10.1083/jcb.201212075.
Full textSeenivasan, Ramkumar, Thomas Hermanns, Tamara Blyszcz, Michael Lammers, Gerrit J. K. Praefcke, and Kay Hofmann. "Mechanism and chain specificity of RNF216/TRIAD3, the ubiquitin ligase mutated in Gordon Holmes syndrome." Human Molecular Genetics 28, no. 17 (April 24, 2019): 2862–73. http://dx.doi.org/10.1093/hmg/ddz098.
Full textGupta, Dipika, Renu Shukla, and Krishnaveni Mishra. "SUMO-targeted Ubiquitin Ligases as crucial mediators of protein homeostasis in Candida glabrata." PLOS Pathogens 20, no. 12 (December 6, 2024): e1012742. https://doi.org/10.1371/journal.ppat.1012742.
Full textAbed, Mona, Eliya Bitman-Lotan, and Amir Orian. "A fly view of a SUMO-targeted ubiquitin ligase." Fly 5, no. 4 (October 1, 2011): 340–44. http://dx.doi.org/10.4161/fly.5.4.17608.
Full textWang, Wei, and Michael J. Matunis. "Paralogue-Specific Roles of SUMO1 and SUMO2/3 in Protein Quality Control and Associated Diseases." Cells 13, no. 1 (December 20, 2023): 8. http://dx.doi.org/10.3390/cells13010008.
Full textSun, Yilun, Lisa M. Miller Jenkins, Yijun P. Su, Karin C. Nitiss, John L. Nitiss, and Yves Pommier. "A conserved SUMO pathway repairs topoisomerase DNA-protein cross-links by engaging ubiquitin-mediated proteasomal degradation." Science Advances 6, no. 46 (November 2020): eaba6290. http://dx.doi.org/10.1126/sciadv.aba6290.
Full textSohn, Sook-Young, and Patrick Hearing. "The adenovirus E4-ORF3 protein functions as a SUMO E3 ligase for TIF-1γ sumoylation and poly-SUMO chain elongation." Proceedings of the National Academy of Sciences 113, no. 24 (May 31, 2016): 6725–30. http://dx.doi.org/10.1073/pnas.1603872113.
Full textBoutell, Chris, Delphine Cuchet-Lourenço, Emilia Vanni, Anne Orr, Mandy Glass, Steven McFarlane, and Roger D. Everett. "A Viral Ubiquitin Ligase Has Substrate Preferential SUMO Targeted Ubiquitin Ligase Activity that Counteracts Intrinsic Antiviral Defence." PLoS Pathogens 7, no. 9 (September 15, 2011): e1002245. http://dx.doi.org/10.1371/journal.ppat.1002245.
Full textWesterbeck, Jason W., Nagesh Pasupala, Mark Guillotte, Eva Szymanski, Brooke C. Matson, Cecilia Esteban, and Oliver Kerscher. "A SUMO-targeted ubiquitin ligase is involved in the degradation of the nuclear pool of the SUMO E3 ligase Siz1." Molecular Biology of the Cell 25, no. 1 (January 2014): 1–16. http://dx.doi.org/10.1091/mbc.e13-05-0291.
Full textHeideker, Johanna, John Prudden, J. Jefferson P. Perry, John A. Tainer, and Michael N. Boddy. "SUMO-Targeted Ubiquitin Ligase, Rad60, and Nse2 SUMO Ligase Suppress Spontaneous Top1–Mediated DNA Damage and Genome Instability." PLoS Genetics 7, no. 3 (March 3, 2011): e1001320. http://dx.doi.org/10.1371/journal.pgen.1001320.
Full textAbed, Mona, Kevin C. Barry, Dorit Kenyagin, Bella Koltun, Taryn M. Phippen, Jeffrey J. Delrow, Susan M. Parkhurst, and Amir Orian. "Degringolade, a SUMO-targeted ubiquitin ligase, inhibits Hairy/Groucho-mediated repression." EMBO Journal 30, no. 7 (February 22, 2011): 1289–301. http://dx.doi.org/10.1038/emboj.2011.42.
Full textErker, Y., H. Neyret-Kahn, J. S. Seeler, A. Dejean, A. Atfi, and L. Levy. "Arkadia, a Novel SUMO-Targeted Ubiquitin Ligase Involved in PML Degradation." Molecular and Cellular Biology 33, no. 11 (March 25, 2013): 2163–77. http://dx.doi.org/10.1128/mcb.01019-12.
Full textWang, Zheng, and Gregory Prelich. "Quality Control of a Transcriptional Regulator by SUMO-Targeted Degradation." Molecular and Cellular Biology 29, no. 7 (January 12, 2009): 1694–706. http://dx.doi.org/10.1128/mcb.01470-08.
Full textPrudden, John, Stephanie Pebernard, Grazia Raffa, Daniela A. Slavin, J. Jefferson P. Perry, John A. Tainer, Clare H. McGowan, and Michael N. Boddy. "SUMO-targeted ubiquitin ligases in genome stability." EMBO Journal 26, no. 18 (August 30, 2007): 4089–101. http://dx.doi.org/10.1038/sj.emboj.7601838.
Full textOhkuni, Kentaro, Yoshimitsu Takahashi, Alyona Fulp, Josh Lawrimore, Wei-Chun Au, Nagesh Pasupala, Reuben Levy-Myers, et al. "SUMO-targeted ubiquitin ligase (STUbL) Slx5 regulates proteolysis of centromeric histone H3 variant Cse4 and prevents its mislocalization to euchromatin." Molecular Biology of the Cell 27, no. 9 (May 2016): 1500–1510. http://dx.doi.org/10.1091/mbc.e15-12-0827.
Full textHickey, Christopher M., and Mark Hochstrasser. "STUbL-mediated degradation of the transcription factor MATα2 requires degradation elements that coincide with corepressor binding sites." Molecular Biology of the Cell 26, no. 19 (October 2015): 3401–12. http://dx.doi.org/10.1091/mbc.e15-06-0436.
Full textFryrear, Kimberly A., Xin Guo, Oliver Kerscher, and O. John Semmes. "The Sumo-targeted ubiquitin ligase RNF4 regulates the localization and function of the HTLV-1 oncoprotein Tax." Blood 119, no. 5 (February 2, 2012): 1173–81. http://dx.doi.org/10.1182/blood-2011-06-358564.
Full textMullen, Janet R., Chi-Fu Chen, and Steven J. Brill. "Wss1 Is a SUMO-Dependent Isopeptidase That Interacts Genetically with the Slx5-Slx8 SUMO-Targeted Ubiquitin Ligase." Molecular and Cellular Biology 30, no. 15 (June 1, 2010): 3737–48. http://dx.doi.org/10.1128/mcb.01649-09.
Full textKoltun, Bella, Eliza Shackelford, François Bonnay, Nicolas Matt, Jean Marc Reichhart, and Amir Orian. "The SUMO-targeted ubiquitin ligase, Dgrn, is essential for Drosophila innate immunity." International Journal of Developmental Biology 61, no. 3-4-5 (2017): 319–27. http://dx.doi.org/10.1387/ijdb.160250ao.
Full textAhner, Annette, Xiaoyan Gong, Bela Z. Schmidt, Kathryn W. Peters, Wael M. Rabeh, Patrick H. Thibodeau, Gergely L. Lukacs, and Raymond A. Frizzell. "Small heat shock proteins target mutant cystic fibrosis transmembrane conductance regulator for degradation via a small ubiquitin-like modifier–dependent pathway." Molecular Biology of the Cell 24, no. 2 (January 15, 2013): 74–84. http://dx.doi.org/10.1091/mbc.e12-09-0678.
Full textHeideker, J., J. J. P. Perry, and M. N. Boddy. "Genome stability roles of SUMO-targeted ubiquitin ligases." DNA Repair 8, no. 4 (April 5, 2009): 517–24. http://dx.doi.org/10.1016/j.dnarep.2009.01.010.
Full textMukhopadhyay, Debaditya, Alexei Arnaoutov, and Mary Dasso. "The SUMO protease SENP6 is essential for inner kinetochore assembly." Journal of Cell Biology 188, no. 5 (March 8, 2010): 681–92. http://dx.doi.org/10.1083/jcb.200909008.
Full textXie, Y., E. M. Rubenstein, T. Matt, and M. Hochstrasser. "SUMO-independent in vivo activity of a SUMO-targeted ubiquitin ligase toward a short-lived transcription factor." Genes & Development 24, no. 9 (April 13, 2010): 893–903. http://dx.doi.org/10.1101/gad.1906510.
Full textLiang, Jason, Namit Singh, Christopher R. Carlson, Claudio P. Albuquerque, Kevin D. Corbett, and Huilin Zhou. "Recruitment of a SUMO isopeptidase to rDNA stabilizes silencing complexes by opposing SUMO targeted ubiquitin ligase activity." Genes & Development 31, no. 8 (April 15, 2017): 802–15. http://dx.doi.org/10.1101/gad.296145.117.
Full textGalanty, Y., R. Belotserkovskaya, J. Coates, and S. P. Jackson. "RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break repair." Genes & Development 26, no. 11 (June 1, 2012): 1179–95. http://dx.doi.org/10.1101/gad.188284.112.
Full textHirota, Kouji, Masataka Tsuda, Junko Murai, Tokiyo Takagi, Islam Shamima Keka, Takeo Narita, Mari Fujita, Hiroyuki Sasanuma, Junya Kobayashi, and Shunichi Takeda. "SUMO-targeted ubiquitin ligase RNF4 plays a critical role in preventing chromosome loss." Genes to Cells 19, no. 10 (September 10, 2014): 743–54. http://dx.doi.org/10.1111/gtc.12173.
Full textBauer, Stefanie L., Jiang Chen, and Stefan U. Åström. "Helicase/SUMO-targeted ubiquitin ligase Uls1 interacts with the Holliday junction resolvase Yen1." PLOS ONE 14, no. 3 (March 21, 2019): e0214102. http://dx.doi.org/10.1371/journal.pone.0214102.
Full textChang, Ya-Chu, Marissa K. Oram, and Anja-Katrin Bielinsky. "SUMO-Targeted Ubiquitin Ligases and Their Functions in Maintaining Genome Stability." International Journal of Molecular Sciences 22, no. 10 (May 20, 2021): 5391. http://dx.doi.org/10.3390/ijms22105391.
Full textAlonso, Annabel, Sonia D'Silva, Maliha Rahman, Pam B. Meluh, Jacob Keeling, Nida Meednu, Harold J. Hoops, and Rita K. Miller. "The yeast homologue of the microtubule-associated protein Lis1 interacts with the sumoylation machinery and a SUMO-targeted ubiquitin ligase." Molecular Biology of the Cell 23, no. 23 (December 2012): 4552–66. http://dx.doi.org/10.1091/mbc.e12-03-0195.
Full textTatham, Michael H., Anna Plechanovová, Ellis G. Jaffray, Helena Salmen, and Ronald T. Hay. "Ube2W conjugates ubiquitin to α-amino groups of protein N-termini." Biochemical Journal 453, no. 1 (June 13, 2013): 137–45. http://dx.doi.org/10.1042/bj20130244.
Full textYu, Bing, Stephen Swatkoski, Alesia Holly, Liam C. Lee, Valentin Giroux, Chih-Shia Lee, Dennis Hsu, et al. "Oncogenesis driven by the Ras/Raf pathway requires the SUMO E2 ligase Ubc9." Proceedings of the National Academy of Sciences 112, no. 14 (March 24, 2015): E1724—E1733. http://dx.doi.org/10.1073/pnas.1415569112.
Full textHan, Jinhua, Li Wan, Guixing Jiang, Liping Cao, Feiyu Xia, Tian Tian, Xiaomei Zhu, et al. "ATM controls the extent of DNA end resection by eliciting sequential posttranslational modifications of CtIP." Proceedings of the National Academy of Sciences 118, no. 12 (March 15, 2021): e2022600118. http://dx.doi.org/10.1073/pnas.2022600118.
Full textKrastev, Dragomir B., and Chris Lord. "Abstract 804: Trapped PARP1 cytotoxicity is modulated by the ubiquitin-dependentsegregase p97." Cancer Research 82, no. 12_Supplement (June 15, 2022): 804. http://dx.doi.org/10.1158/1538-7445.am2022-804.
Full textNatalie Winteringham, Louise, Raelene Endersby, Jennifer Beaumont, Jean-Philippe Lalonde, Merlin Crossley, and Svend Peter Klinken. "Hls5, a Novel Ubiquitin E3 Ligase, Modulates Levels of Sumoylated GATA-1." Blood 114, no. 22 (November 20, 2009): 253. http://dx.doi.org/10.1182/blood.v114.22.253.253.
Full textDelegkou, Georgia N., Maria Birkou, Nefeli Fragkaki, Tamara Toro, Konstantinos D. Marousis, Vasso Episkopou, and Georgios A. Spyroulias. "E2 Partner Tunes the Ubiquitylation Specificity of Arkadia E3 Ubiquitin Ligase." Cancers 15, no. 4 (February 7, 2023): 1040. http://dx.doi.org/10.3390/cancers15041040.
Full textNie, Minghua, Aaron Aslanian, John Prudden, Johanna Heideker, Ajay A. Vashisht, James A. Wohlschlegel, John R. Yates, and Michael N. Boddy. "Dual Recruitment of Cdc48 (p97)-Ufd1-Npl4 Ubiquitin-selective Segregase by Small Ubiquitin-like Modifier Protein (SUMO) and Ubiquitin in SUMO-targeted Ubiquitin Ligase-mediated Genome Stability Functions." Journal of Biological Chemistry 287, no. 35 (June 22, 2012): 29610–19. http://dx.doi.org/10.1074/jbc.m112.379768.
Full textLiebelt, Frauke, and Alfred C. O. Vertegaal. "Ubiquitin-dependent and independent roles of SUMO in proteostasis." American Journal of Physiology-Cell Physiology 311, no. 2 (August 1, 2016): C284—C296. http://dx.doi.org/10.1152/ajpcell.00091.2016.
Full textTan, Wei, Zheng Wang, and Gregory Prelich. "Physical and Genetic Interactions Between Uls1 and the Slx5–Slx8 SUMO-Targeted Ubiquitin Ligase." G3: Genes|Genomes|Genetics 3, no. 4 (March 11, 2013): 771–80. http://dx.doi.org/10.1534/g3.113.005827.
Full textScherer, Myriam, Nina Reuter, Nadine Wagenknecht, Victoria Otto, Heinrich Sticht, and Thomas Stamminger. "Small ubiquitin-related modifier (SUMO) pathway-mediated enhancement of human cytomegalovirus replication correlates with a recruitment of SUMO-1/3 proteins to viral replication compartments." Journal of General Virology 94, no. 6 (June 1, 2013): 1373–84. http://dx.doi.org/10.1099/vir.0.051078-0.
Full textGong, Xiaoyan, Annette Ahner, Ariel Roldan, Gergely L. Lukacs, Patrick H. Thibodeau, and Raymond A. Frizzell. "Non-native Conformers of Cystic Fibrosis Transmembrane Conductance Regulator NBD1 Are Recognized by Hsp27 and Conjugated to SUMO-2 for Degradation." Journal of Biological Chemistry 291, no. 4 (December 1, 2015): 2004–17. http://dx.doi.org/10.1074/jbc.m115.685628.
Full textHembram, Dambarudhar Shiba Sankar, Hitendra Negi, Poulomi Biswas, Vasvi Tripathi, Lokesh Bhushan, Divya Shet, Vikas Kumar, and Ranabir Das. "The Viral SUMO–Targeted Ubiquitin Ligase ICP0 is Phosphorylated and Activated by Host Kinase Chk2." Journal of Molecular Biology 432, no. 7 (March 2020): 1952–77. http://dx.doi.org/10.1016/j.jmb.2020.01.021.
Full textGuérillon, Claire, Stine Smedegaard, Ivo A. Hendriks, Michael L. Nielsen, and Niels Mailand. "Multisite SUMOylation restrains DNA polymerase η interactions with DNA damage sites." Journal of Biological Chemistry 295, no. 25 (April 29, 2020): 8350–62. http://dx.doi.org/10.1074/jbc.ra120.013780.
Full textChang, Hui-Ming, and Edward T. H. Yeh. "SUMO: From Bench to Bedside." Physiological Reviews 100, no. 4 (October 1, 2020): 1599–619. http://dx.doi.org/10.1152/physrev.00025.2019.
Full textConn, Kristen L., Peter Wasson, Steven McFarlane, Lily Tong, James R. Brown, Kyle G. Grant, Patricia Domingues, and Chris Boutell. "Novel Role for Protein Inhibitor of Activated STAT 4 (PIAS4) in the Restriction of Herpes Simplex Virus 1 by the Cellular Intrinsic Antiviral Immune Response." Journal of Virology 90, no. 9 (March 2, 2016): 4807–26. http://dx.doi.org/10.1128/jvi.03055-15.
Full textBrown, James R., Kristen L. Conn, Peter Wasson, Matthew Charman, Lily Tong, Kyle Grant, Steven McFarlane, and Chris Boutell. "SUMO Ligase Protein Inhibitor of Activated STAT1 (PIAS1) Is a Constituent Promyelocytic Leukemia Nuclear Body Protein That Contributes to the Intrinsic Antiviral Immune Response to Herpes Simplex Virus 1." Journal of Virology 90, no. 13 (April 20, 2016): 5939–52. http://dx.doi.org/10.1128/jvi.00426-16.
Full textSobko, Alex. "A hypothetical MEK1-MIP1-SMEK multiprotein signaling complex may function in Dictyostelium and mammalian cells." International Journal of Developmental Biology 64, no. 10-11-12 (2020): 495–98. http://dx.doi.org/10.1387/ijdb.200140as.
Full textCook, Caitlin E., Mark Hochstrasser, and Oliver Kerscher. "The SUMO-targeted ubiquitin ligase subunit Slx5 resides in nuclear foci and at sites of DNA breaks." Cell Cycle 8, no. 7 (April 2009): 1080–89. http://dx.doi.org/10.4161/cc.8.7.8123.
Full textYin, Y., A. Seifert, J. S. Chua, J. F. Maure, F. Golebiowski, and R. T. Hay. "SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage." Genes & Development 26, no. 11 (June 1, 2012): 1196–208. http://dx.doi.org/10.1101/gad.189274.112.
Full textGuo, Xin, Andrea Baillo, Sucharita M. Dutta, Oliver Kerscher, and O. Semmes. "HTLV-1 Tax binds to and stabilizes the SUMO-targeted ubiquitin ligase RNF4 during DNA damage response." Retrovirology 11, Suppl 1 (2014): P98. http://dx.doi.org/10.1186/1742-4690-11-s1-p98.
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