Academic literature on the topic 'Sulphasalazine'

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Journal articles on the topic "Sulphasalazine"

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&NA;. "Sulphasalazine." Reactions Weekly &NA;, no. 969 (September 2003): 14. http://dx.doi.org/10.2165/00128415-200309690-00044.

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Freeman, Hugh J., Urs P. Steinbrecher, WC Peter Kwan, and Stephanie Ensworth. "Sulphasalazine-Induced Pseudomembranous Colitis." Canadian Journal of Gastroenterology 5, no. 5 (1991): 167–70. http://dx.doi.org/10.1155/1991/420864.

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An 18-year-old female with ankylosing spondylitis developed fever, abdominal pain and diarrhea on two occasions after starting sulphasalazine therapy. Flexible sigmoidoscopy revealed pseudomembranous colitis; fecal cultures were positive forClostridium difficile; andC difficiletoxin assay was positive. Despite the frequent use of sulphasalazine in the management of inflammatory bowel disease, this complication has been apparently rare. Clinicians should be wary of the onset of diarrhea in patients receiving sulphasalazine, whether for inflammatory bowel disease or other conditions.
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Jennings, P. E., R. L. Blandford, and F. D. Rosenthal. "Acute sulphasalazine hepatotoxicity." Postgraduate Medical Journal 62, no. 726 (April 1, 1986): 305–6. http://dx.doi.org/10.1136/pgmj.62.726.305.

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Rijk, Marno C. M. "Sulphasalazine and Prednisone Compared with Sulphasalazine for Treating Active Crohn Disease." Annals of Internal Medicine 114, no. 6 (March 15, 1991): 445. http://dx.doi.org/10.7326/0003-4819-114-6-445.

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Bax, D. E., R. S. Amos, D. Situnayake, and B. Mcconkey. "SULPHASALAZINE IN RHEUMATOID ARTHRITIS." Lancet 325, no. 8443 (June 1985): 1450. http://dx.doi.org/10.1016/s0140-6736(85)91878-1.

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VYSE, T., and A. K. L. SO. "SULPHASALAZINE INDUCED AUTOIMMUNE SYNDROME." Rheumatology 31, no. 2 (1992): 115–16. http://dx.doi.org/10.1093/rheumatology/31.2.115.

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McCONKEY, B. "SULPHASALAZINE AND ANKYLOSING SPONDYLITIS." Rheumatology 29, no. 1 (1990): 1–3. http://dx.doi.org/10.1093/rheumatology/29.1.1.

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Pullar, T., J. A. Hunter, and H. A. Capell. "SULPHASALAZINE IN RHEUMATOID ARTHRITIS." Lancet 325, no. 8438 (May 1985): 1167. http://dx.doi.org/10.1016/s0140-6736(85)92477-8.

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Feltelius, N., and R. Hallgren. "Sulphasalazine in ankylosing spondylitis." Annals of the Rheumatic Diseases 45, no. 5 (May 1, 1986): 396–99. http://dx.doi.org/10.1136/ard.45.5.396.

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Amos, R. S., D. E. Bax, and M. S. Greaves. "Sulphasalazine therapy in RA." Annals of the Rheumatic Diseases 45, no. 5 (May 1, 1986): 439. http://dx.doi.org/10.1136/ard.45.5.439-a.

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Dissertations / Theses on the topic "Sulphasalazine"

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Hooi, Peh Kheng. "Actions of balsalazide and sulphasalazine on mast cells." Thesis, University College London (University of London), 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.294805.

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Mackay, James Morrison. "Inflammatory bowel disease and sulphasalazine therapy : a cytogenetic study." Thesis, University of Aberdeen, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.375918.

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Ulcerative colitis and Crohn's colitis are chronic inflammatory bowel diseases that occur with a high frequency in the North-East of Scotland. They are diseases of adolescents and young adults, although they may have their onset at any age. The aetiology is largely unknown. Oral sulphasalazine is used as the treatment of choice for the prevention of relapses. At present there is no satisfactory alternative and so, on present practice, patients may take the drug indefinitely after diagnosis of the disease. Inflammatory bowel disease itself does not increase the levels of sister chromatid exchange and micronuclei observed in the lymphocytes of the patients. Patients receiving sulphasalazine therapy, however, have significantly elevated levels of sister chromatid exchange and micronuclei in their lymphocytes compared to control individuals. In addition, patients show a significant elevation in sister chromatid exchange and micronuclei frequencies after commencing sulphasalazine therapy. The length of time on sulphasalazine is influential in determining the sister chromatid exchange frequency as is the acetylator phenotype of the patient. Sister chromatid exchange frequencies appear to remain elevated for many months after cessation of therapy, suggesting that the lesions produced by the sulphasalzine therapy are long-lived. In vitro studies have shown that sulphasalazine induces both sister chromatid exchange and micronuclei in human lymphocytes, whereas sulphapyridine and its acetylated metabolites induce only sister chromatid exchanges. 5-aminosalicylic acid, the active moiety of sulphasalazine, and its acetylated metabolite do not induce sister chromatid exchange or micronuclei at the concentrations tested. The present and future use of sulphasalazine therapy should be evaluated in light of these results, and the use of new drugs, based on the 5-aminosalicylic moiety should be encouraged to reduce the potential genetic risk to the patients.
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Gunnarsson, Iva. "SLE : pathogenetic mechanisms in nephritis and sulphasalazine-induced lupus reactions /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3654-4/.

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Ireland, Alan C. "Metabolism and mode of action of 5-aminosalicylic acid and its derivatives." Thesis, University of Oxford, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.236211.

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Garg, Ganesh Prasad. "The gastric antiulcer action of sulphasalazine in cold-restrained rats : implications of leukotriene involvement in stress ulcer aetiology /." [Hong Kong : University of Hong Kong], 1991. http://sunzi.lib.hku.hk/hkuto/record.jsp?B12993128.

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Garg, Ganesh Prasad. "The gastric antiulcer action of sulphasalazine in cold-restrainedrats: implications of leukotriene involvementin stress ulcer aetiology." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1991. http://hub.hku.hk/bib/B31232206.

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Books on the topic "Sulphasalazine"

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Gibson, Stephen Anthony. A survey of adverse reactions to sulphasalazine. Bradford, 1987.

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Turney, Ben, and John Reynard. Kidney stones. Edited by John Reynard. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199659579.003.0013.

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The composition of kidney stones is variable and the predisposing factors multifactorial. Consequently, a detailed evaluation of the patient’s lifestyle, diet, fluid intake, medical history, drug history, urinary tract anatomy, blood, and urine biochemistry and stone composition is required determine predisposing factors for stone formation in an individual patient. Combinatorial subtle variants in biochemistry may act synergistically to increase risk of stone formation/recurrence. Many medications may alter blood and/or urine biochemistry and predispose to stone formation. Corticosteroids increase absorption of calcium from the gut and cause hypercalciuria. Topirimate (for seizures or migraines), sulphasalazine (for rheumatoid arthritis), diuretics containing triamterene, acetazolamide (for myotonia), antacids containing trisilicate, calcium supplements, vitamin D supplements, vitamin C in high doses, indinavir (for HIV), and some herbal medicines (containing ephedrine) all increase stone risk.
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Radical intervention in early rheumatoid arthritis: The case for enteric-coated sulphasalazine, methotrexate and combination regimes : a workshop held in Camogli, Italy, September 1994. Oxford: Oxford University Press, 1995.

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Book chapters on the topic "Sulphasalazine"

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Varbanova, Boriana B., and E. D. Dyankov. "Sulphasalazine." In Rheumaderm, 331–36. Boston, MA: Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4857-7_50.

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Waldvogel, Herman Hans. "Sulfasalazin rINN, USAN, Sulphasalazine BAN." In Analgetika Antinozizeptiva Adjuvanzien, 674–79. Berlin, Heidelberg: Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-642-56710-0_99.

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O’morain, C., P. Smethurst, and A. J. Levi. "Reversible male infertility induced by sulphasalazine." In Male Fertility and Its Regulation, 49–54. Dordrecht: Springer Netherlands, 1985. http://dx.doi.org/10.1007/978-94-009-4894-5_5.

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Hadziselimovic, F., B. Keller, U. Hennes, and U. Schaub. "Toxic effect of sulphasalazine on prepubertal testes." In Inflammatory Bowel Disease and Coeliac Disease in Children, 99–115. Dordrecht: Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-009-1850-4_8.

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Farr, M., D. G. I. Scott, and P. A. Bacon. "Side-effect profile of sulphasalazine in inflammatory arthritis." In Side-Effects of Anti-Inflammatory Drugs, 279–80. Dordrecht: Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-010-9775-8_30.

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Taggart, A. J. "The Clinical Efficacy of Sulphasalazine in Rheumatic Disease." In Basis for Variability of Response to Anti-Rheumatic Drugs, 189–96. Basel: Birkhäuser Basel, 1988. http://dx.doi.org/10.1007/978-3-0348-9160-8_18.

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Situnayake, R. D., and B. McConkey. "Clinical aspects and side-effects of sulphasalazine in the treatment of rheumatoid arthritis." In Side-Effects of Anti-Inflammatory Drugs, 209–21. Dordrecht: Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-010-9775-8_23.

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Hoult, J. R. S. "Sulphasalazine: mode of action and side-effects in rheumatoid arthritis and ulcerative colitis." In Side-Effects of Anti-Inflammatory Drugs, 223–34. Dordrecht: Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-010-9775-8_24.

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"Sulphasalazine." In Dictionary of Rheumatology, 202. Vienna: Springer Vienna, 2009. http://dx.doi.org/10.1007/978-3-211-79280-3_1065.

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"Sulphasalazine in rheumatoid arthritis – a double-blind comparison of sulphasalazine with placebo and sodium aurothiomalate." In Classic Papers in Rheumatology, 432–33. CRC Press, 2001. http://dx.doi.org/10.3109/9780203214237-212.

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Conference papers on the topic "Sulphasalazine"

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Sökücü, Sinem Nedime, Cengiz Özdemir, Özlem Kahya, and Seda Tural Önür. "Eosinophilic Pneumonia Due to Sulphasalazine Use." In ERS International Congress 2018 abstracts. European Respiratory Society, 2018. http://dx.doi.org/10.1183/13993003.congress-2018.pa3026.

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Gnjidic, Z., and M. Gnjidic. "AB0134 Sulphasalazine (salazopyrine en) in treatment of reactive arthritis (efficacy, safety and tolerability)." In Annual European Congress of Rheumatology, Annals of the rheumatic diseases ARD July 2001. BMJ Publishing Group Ltd and European League Against Rheumatism, 2001. http://dx.doi.org/10.1136/annrheumdis-2001.343.

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Morovic-Vergles, J., K. Berdnik-Gortan, and D. Soldo-Juresa. "AB0055 Sulphasalazine in the treatment of rheumatoid arthritis: a 2 year prospective study." In Annual European Congress of Rheumatology, Annals of the rheumatic diseases ARD July 2001. BMJ Publishing Group Ltd and European League Against Rheumatism, 2001. http://dx.doi.org/10.1136/annrheumdis-2001.1116.

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Tchepeleva, SN, GV Loukina, and YA Sigidin. "AB0126 Assessment of sulphasalazine (ss) and methotrexate (mt) efficacy in treatment of ankylosing spondylitis (as).(preliminary data)." In Annual European Congress of Rheumatology, Annals of the rheumatic diseases ARD July 2001. BMJ Publishing Group Ltd and European League Against Rheumatism, 2001. http://dx.doi.org/10.1136/annrheumdis-2001.335.

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