Academic literature on the topic 'Sulfamerazine'

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Journal articles on the topic "Sulfamerazine"

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Chuang, Li Chin, Chin Hsiang Luo, and Sing Wei Huang. "Degradation Mechanism of Aqueous Sulfamerazine by AOPs of O3 and UV/TiO2." Advanced Materials Research 396-398 (November 2011): 772–75. http://dx.doi.org/10.4028/www.scientific.net/amr.396-398.772.

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Advanced Oxidation Processes (AOPs) is a promising treatment technology for eliminating trace micropollutants, in the treatment of wastewaters containing sulfamerazine (one of pharmaceuticals) using O3 and UV/TiO2 process, respectively. The degradation was studied by monitoring the intermediates employing high performance liquid chromatography (HPLC) separation coupled with an atmospheric pressure ionization mass spectrometry (API-MS) system operated under selected ion monitoring (SIM). The results indicate that the original sulfamerazine almost was degraded within 90 min under the concentration of ozone 3 mg/L at different pH runs. The ozonation of sulfamerazine demonstrated the best degradation efficiency for runs at pH 8 than for runs at pH 6 and pH 11, respectively, under the concentration of ozone 1 or 3 mg/L. The original sulfamerazine was completely degraded within irradiation time of 5 hr at pH 6 runs in the concentration of O2-sparged 30 mg/L during the photocatalytic process. The rate constants are 0.086, 0.08, 0.04, and 0.027 hr-1 at the concentration of sulfamerazine 14.22, 21.33, 35.55, and 42.66 μM, respectively. Two intermediates were observed during the photocatalytic degradation of sulfamerazine.
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Chen, Lei, Yean Kee Lee, Yanawut Manmana, Kheng Soo Tay, Vannajan Sanghiran Lee, and Noorsaadah Abd Rahman. "Synthesis, characterization, and theoretical study of an acrylamide-based magnetic molecularly imprinted polymer for the recognition of sulfonamide drugs." e-Polymers 15, no. 3 (May 1, 2015): 141–50. http://dx.doi.org/10.1515/epoly-2015-0017.

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AbstractIn this work, a magnetic molecularly imprinted polymer (MION-MIP) was prepared for the recognition and extraction of sulfadiazine (SDZ). The acrylamide-based MIP was imprinted directly onto the surface of 3-(trimethoxysilyl)propyl methacrylate-modified magnetic iron oxide nanoparticles. The synthesized MION-MIP with a diameter about 100 nm possesses fast adsorption kinetics and high adsorption capacity. The results also indicated that a higher maximum adsorption capacity (775 μg g-1) was achieved by the synthesized MION-MIP. The Langmuir adsorption isotherm model was found to describe well the equilibrium adsorption data. The results from the competitive binding experiment showed that MION-MIP was not only selective toward SDZ but the adsorption of sulfamerazine was also dramatically high. SDZ and sulfamerazine have an almost similar substructure where these two compounds were only differentiated by one methyl group. To explain this result, a computational study was carried out. From a different level of calculation with semiempirical (PM3), Hartree-Fock (HF), and density functional theory (DFT) calculation, SDZ and sulfamerazine showed similar interaction energy and interaction mechanism with the acrylamide monomer. Therefore, both SDZ and sulfamerazine could have the same binding property with the MION-MIP.
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Malla, Avirup, Koel Mukherjee, Mukulika Mandal, Aishwarya Mukherjee, Runa Sur, and Suvroma Gupta. "An Insight to the Toxic Effect of Sulfamerazine on Porcine Pancreatic Amylase and Lactate Dehydrogenase Activity: An In Vitro Study." Current Chemical Biology 15, no. 2 (August 9, 2021): 171–81. http://dx.doi.org/10.2174/2212796815666210216101221.

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Background: Sulfamerazine, a sulfonamide, has been routinely used to treat various bacterial infections, namely Pneumonia, Urinary tract infections, Shigellosis, Bronchitis, Prostatitis, and many more. It interferes with the bacterial folic acid biosynthesis, albeit higher eukaryotes are not susceptible to its action due to the inherent absence of this specific pathway. Objective: In spite of its constant use, Sulfamerazine administration evokes serious issues like the development of antibacterial resistance through environmental contamination, although how it affects the eukaryotic system, specifically its target identification, has not been addressed in detail. Methods: The source of the cell line, including when and from where it was obtained. Whether the cell line has recently been authenticated and by what method. Whether the cell line has recently been tested for mycoplasma contamination. Hela Cells are cultured as per the standard method, amylase and lactate dehydrogenase assay are conducted using a standard procedure with a spectrophotometer. Binding thermodynamics and conformational study have been estimated with isothermal titration calorimetry as well as with docking. Results: Experimental observations reveal that Sulfamerazine inhibits porcine pancreatic amylase in a noncompetitive mode (IC50 of 0.96 mM). The binding of the drug to porcine pancreatic amylase is entropy-driven with conformational changes of the protein as indicated by concomitant redshift. It enhances the inhibitory effects of acarbose and cetapin on their in vitro pancreatic amylase activity. It augments lipid peroxidation and promotes lactic acidosis in a dose-dependent manner. Docking studies ensure effective interactions between Sulfamerazine and proteins like lactic dehydrogenase and porcine pancreatic amylase. Conclusion: Detailed study is to be conducted to confirm whether the molecular scaffold of Sulfamerazine might serve as an effective repurposed drug acting as a lead molecule to design antidiabetic drugs of future use. Alternatively, it should be prescribed with caution under specific medical situations like diabetes, cancer and hepatic disorders manifesting lactic acidosis to avoid the crisis.
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Hossain, G. M. Golzar. "A new polymorph of sulfamerazine." Acta Crystallographica Section E Structure Reports Online 62, no. 6 (May 5, 2006): o2166—o2167. http://dx.doi.org/10.1107/s1600536806014449.

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Yao, Youru, Na Mi, Yongqing Zhu, Li Yin, Yong Zhang, and Shiyin Li. "Efficient removal of sulfamerazine (SMR) by ozonation in acetic acid solution after enrichment SMR from water using granular activated carbon." RSC Advances 9, no. 16 (2019): 9145–52. http://dx.doi.org/10.1039/c8ra10429h.

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Zhang, Geoff G. Z., Chonghui Gu, Mark T. Zell, R. Todd Burkhardt, Eric J. Munson, and David J. W. Grant. "Crystallization and Transitions of Sulfamerazine Polymorphs." Journal of Pharmaceutical Sciences 91, no. 4 (April 2002): 1089–100. http://dx.doi.org/10.1002/jps.10100.

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Smallidge, Robert L., Elzbieta J. Kentzer, Kelly R. Stringham, Eun H. Kim, Connie Lehe, Rodger W. Stringham, and Elizabeth C. Mundell. "Sulfamethazine and Sulfathiazole Determination at Residue Levels in Swine Feeds by Reverse-Phase Liquid Chromatography with Post-Column Derivatization." Journal of AOAC INTERNATIONAL 71, no. 4 (July 1, 1988): 710–17. http://dx.doi.org/10.1093/jaoac/71.4.710.

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Abstract Twenty g sample, to which sulfamerazine has been added as internal standard, is extracted with 0.3N HC1 + 1.5% diethylamine in 25% methanol. The sample extract is chilled (to aid clarification), centrifuged, and filtered. The sulfonamides are separated from each other and from co-extracted materials on a C-18 reverse-phase column and detected at 450 nm following post-column derivatization with dimethylaminobenzaldehyde. Two isocratic mobile phases have been tested: (1) acetonitrile-2% acetic acid (17 + 83), with an analysis time of 13 min; and (2) acetonitrile-methanol-2% acetic acid (4 + 16 + 80), with an analysis time of 20 min but an improved analysis for some samples. As many as 40 samples have been analyzed at one time unattended with the aid of an autosampler. A total of about 1500 field samples have been assayed using the method. Method sensitivity is 0.1 ppm for either analyte in a hog finishing feed. Linearity for each of the analytes is satisfactory over a range of 0.4-25 ppm in spiked feeds. Coefficients of variation range from 13% at 0.5 ppm to 2% at 13 ppm as tested over a period of time in naturally contaminated samples. The absolute recovery of sulfamethazine varies with sample matrix, but, in the presence of sulfamerazine as internal standard, recovery has been 96.7-99.7% over the range of 0.1-10 ppm. Sulfamerazine and sulfamoxole were tested for their suitability as internal standards. Sulfamerazine is a good internal standard for sulfamethazine; neither is ideal for sulfathiazole. A recovery factor is necessary for estimating the level of sulfathiazole in feeds when either internal standard is used; however, either standard is satisfactory for correcting for feed matrix variation
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Vosough, Maryam, Mahdieh Nazari Onilghi, and Amir Salemi. "Optimization of matrix solid-phase dispersion coupled with high performance liquid chromatography for determination of selected antibiotics in municipal sewage sludge." Analytical Methods 8, no. 24 (2016): 4853–60. http://dx.doi.org/10.1039/c6ay00112b.

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Deng, Fengxia, Jinyu Xie, Orlando Garcia-Rodriguez, Baojian Jing, Yingshi Zhu, Zhonglin Chen, Jyh-Ping Hsu, Jizhou Jiang, Shunwen Bai, and Shan Qiu. "Correction: A dynamic anode boosting sulfamerazine mineralization via electrochemical oxidation." Journal of Materials Chemistry A 10, no. 4 (2022): 2133. http://dx.doi.org/10.1039/d1ta90273c.

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Liu, Chengxiang, Fengjuan Cao, Samir A. Kulkarni, Geoffrey P. F. Wood, and Erik E. Santiso. "Understanding Polymorph Selection of Sulfamerazine in Solution." Crystal Growth & Design 19, no. 12 (October 9, 2019): 6925–34. http://dx.doi.org/10.1021/acs.cgd.9b00576.

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Dissertations / Theses on the topic "Sulfamerazine"

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Kováčová, Lucia. "Automatizace extrakce sulfamerazinu s využitím LOV techniky." Master's thesis, 2015. http://www.nusl.cz/ntk/nusl-335141.

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Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Analytical chemistry Candidate: Lucia Kováčová Supervisor: Warunya Boonjob, Ph.D. Consultant: Doc. PharmDr. Hana Sklenářová, Ph.D. Title of diploma work: Automation of sulfamerazine extraction using LOV technique This theses deals with development of the method to determine sulfamerazine in spiked serum using the LOV methodology. The analyte was preconcentrated on sorbent Oasis- HLB. Pure methanol was used as eluent. UV spectrophotometry with wavelenght 275 nm was used as detection technique . The optimal conditions of measurement in SIA system were specified - the creation of microcolumn, the volume of analyte, the analyte aspiration and elution flowrates. The linear calibration curve was found with the correlation coeficient of 0.99950 in the concentration range of 50 - 1000 ppb. The limit of detection (LOD = 71.70 µg/L) and the limit of quantification (LOQ = 238.99 µg/L) were defined. The repeatability for concentrations of 500 ppb and 1000 ppb were measured. The relative standard deviations (RSDs) were 5.66% and 6.60%, respectively.
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Book chapters on the topic "Sulfamerazine"

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Beyer, Karl-Heinz. "Sulfamerazin." In Biotransformation der Arzneimittel, 511–12. Berlin, Heidelberg: Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-74386-3_297.

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Gramatté, T., B. Terhaag, E. Fischer, and F. Varga. "The Biliary Elimination of Sulfamerazin in Rat and Man — a Comparison." In Archives of Toxicology, 348–50. Berlin, Heidelberg: Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-69928-3_70.

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Conference papers on the topic "Sulfamerazine"

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Patel, Mahesh K., Sanjay M. Tailor, and Urmila H. Patel. "DFT study and Hirshfeld surface analysis of third polymorph of sulfamerazine." In INTERNATIONAL CONFERENCE ON CONDENSED MATTER AND APPLIED PHYSICS (ICC 2015): Proceeding of International Conference on Condensed Matter and Applied Physics. Author(s), 2016. http://dx.doi.org/10.1063/1.4946308.

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Yao, Qiufang, Bitao Fan, Ye Xiong, Chao Wang, and Qingfeng Sun. "Adsorptive Removal of Sulfamerazine from Water by modified Cellulose Nanofibers Aerogel." In 2016 2nd International Conference on Advances in Energy, Environment and Chemical Engineering (AEECE 2016). Paris, France: Atlantis Press, 2016. http://dx.doi.org/10.2991/aeece-16.2016.43.

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