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Mashuri, Mashuri, and Ayudia Hardiayani Kiranaratri. "Study of Modelling Synthetic Unit Hydograph Using ITB-1 Method (Case Study: Upstream Siak Watershed)." JURNAL KAJIAN TEKNIK SIPIL 4, no. 2 (September 20, 2019): 99–108. http://dx.doi.org/10.52447/jkts.v4i2.1685.
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Analysis of unmeasured flow rates in watershed with the Syntetic Hydrograph Unit (SUH) Method is the most practical and simple method. This method requires watershed characteristics as river length and watershed area. Calculation and flow rate data are very useful in the development of water resources science and civil building planning especially in water construction work. Today, the Syntetic Unit Hydrograph (SUH) Method has been widely developed and most recently the ITB-1 Syntetic Unit Hydrograph (SUH) Method. The reliability of SUH ITB-1 in Sungai Tapung Kanan and Sungai Tapung Kiri shows good performance. This is indicated by the accuracy of the volume of the Tapung Kanan River 96.30% and the accuracy of the Tapung Kiri River 99.88%. The volume control ratio / direct run off (DRO) Sungai Tapung Kanan 1,00006 and Sungai Tapung Kiri 1,000088 (close to 1). While the peak discharge produced by Tapung Kanan River is 39,950 m3/ sec and Tapung Kiri River is 38,867 m3/sec.
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Christopher, Cleon, Bobby Minola Ginting, Doddi Yudianto, and Albert Wicaksono. "Comparison of Direct Runoff Values Between Numerical Model and Convolution of Synthetic Unit Hydrograph Method." MEDIA KOMUNIKASI TEKNIK SIPIL 28, no. 1 (July 29, 2022): 19–31. http://dx.doi.org/10.14710/mkts.v28i1.42309.
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This paper compares the results of direct runoff obtained by a numerical model of the shallow water equations (SWE) with the synthetic unit hydrograph (SUH) methods generally used in Indonesia. It is known that such SUH methods are still empirical, thus making it difficult for users to determine a representative method. Meanwhile, the hydrodynamic approach such as the SWE numerical model can achieve more accurate results in predicting the direct runoff compared to the SUH methods, because the model itself is derived mathematically based on the physical processes. The findings indicate that the direct runoff predicted using the SWE numerical model (HEC-RAS 5.0.7) produced more accurate results for the peak discharge with an average error of -0.07%, the peak time with an average error of 19.77%, and the shape of the hydrograph with the smallest Root Mean Square Error (RMSE) from all the cases tested. Therefore, it can be concluded that in the future the use of a hydrodynamic approach is highly recommended for the direct runoff prediction. This paper was also aimed to be used as a reference in the development of new, more accurate SUH method in the future.
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Shaikh, Mohamedmaroof P., Sanjaykumar M. Yadav, and Vivek L. Manekar. "Assessment of the empirical methods for the development of the synthetic unit hydrograph: a case study of a semi-arid river basin." Water Practice and Technology 17, no. 1 (December 1, 2021): 139–56. http://dx.doi.org/10.2166/wpt.2021.117.
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Abstract This study aims to assess various empirical synthetic unit hydrograph (SUH) methods and find the best method. Ideally, each river should have a definite rain gauge station (RGS) to get sufficient rainfall data that is available for carrying out meaningful analysis. The provisions of Indian Standard (IS) 4987:1994 determined the optimum number of RGS. In the absence of RGS, the SUH is recommended. SUHs have been developed using various methods such as Snyder's, Taylor and Schwarz, Soil Conservation Service, Mitchell's and Central Water Commission (CWC). In the present study, the Rel River Basin (RRB) is considered as the study area which has two existing RGS. IS 4987:1994 suggested that four RGS are required for more reliable rainfall data. Various efficiency criteria such as Correlation Coefficient, Pearson Coefficient, Nash Sutcliffe Efficiency, Index of Agreement, Normalized Root Mean Square Error, Mean Absolute Error, Root Mean Square Error and Kling-Gupta Efficiency have been used to compare SUH methods. The ranking of SUH methods was reported based on the compound factor (CF) through efficiency criteria. The 1.125 CF was observed as the minimum for the CWC method and recommended for determining peak discharge and timing for the study area.
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Suh, I. H., J. M. Suh, T. S. Ko, K. Aoki, and H. Yamazaki. "Rationale of a quick adjustment method for crystal orientation in oscillation photography. Erratum." Journal of Applied Crystallography 22, no. 2 (April 1, 1989): 183–84. http://dx.doi.org/10.1107/s0021889889001421.
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In the paper by Suh, Suh, Ko, Aoki & Yamazaki [J. Appl. Cryst. (1988). 21, 521–523], the penultimate sentence of the Concluding remarks section is in error. The correct sentence is Subtract the deviation in the bottom half from the deviation in the top half to give the correction for the vertical arc: if the result is + Δν mm, rotate the vertical arc by Δv ° clockwise, and by Δν ° anticlockwise in the case of −Δν mm.
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Olea, R., J. H. Guy, H. Edge, and S. A. Edwards. "The pigmeat supply chain: pre-assessment for a Life Cycle Inventory." Proceedings of the British Society of Animal Science 2009 (April 2009): 126. http://dx.doi.org/10.1017/s1752756200029653.
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Formulating the inventory of relevant commodities to assess the life cycle of goods or services (LCI) is highly demanding on time and resources (Suh et al., 2004). Collected information is not always satisfactory to take account of all possible sources of environmental burdens (E-burdens) produced in the commodity supply chain. Several pre-assessment methods have been proposed to serve this function, although these have identified limitations; lack of previous experience and use of subjective cut off criteria are the most frequent weaknesses found (Suh, 2006). An objective pre-assessment method was developed as part of a life cycle analysis (LCA) for different pigmeat supply chain (PSC) scenarios.
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Buana, Hadi, Lily Montarcih Limantara, Pitojo Tri Juwono, and Moh Sholichin. "THE CHARACTERISTIC OF WATERSHED MORPHOMETRY DATA FOR SUPPORTING THE MODIFICATION MODELING OF NAKAYASU SYNTHETIC UNIT HYDROGRAPH." Journal of Southwest Jiaotong University 57, no. 4 (August 29, 2022): 543–50. http://dx.doi.org/10.35741/issn.0258-2724.57.4.47.
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This research aimed to investigate the characteristics of watershed morphometry that affect the main parameter that forms the Nakayasu Synthetic Unit Hydrograph (SUH). The result is will support the modification modeling of Nakayasu SUH. The formulation of time like (in the Nakayasu SUH) itself consists of the physical characteristic such as the main river length (L) that is limited regarding the category of main river length such as L > 15 km and L < 15 km. Due to the specific characteristics of the Nakayasu SUH formulation, this research will focus on the development of the Nakayasu SUH formulation by modification by adding the watershed characteristic parameter to the time lag (tg). This research was conducted in the 23 watersheds in Indonesia, which have the Automatic Water Level Recorder (AWLR) and Automatic Rainfall Recorder (ARR). However, this research is conducted on the 7 morphometry and time lag data that are watershed area (A), the length of the main river (L), river slope (I), river density (D), the river length to the eight point of watershed (Lc), the factor of H (H = L.Lc), watershed perimeter (O = O), and time lag. The time lag of each watershed is analyzed using the straight line method; however, the watershed morphometry data is analyzed by using the software of ArcGIS and analyzing the river/drainage density and the factor of river length and river length to the weight point of watershed. The results show five morphometry variables that very influenced the time lag (one of the variables in the Nakayasu SUH model): A, Lc, H, L, and O. The other two variables are not affected by the time lag: D and K.
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Asta, Asta, and Nurjaya Nurjaya. "Estimasi Debit Puncak Menggunakan Hidrograf Satuan Sintetik Pada Daerah Aliran Sungai Kayan Kabupaten Bulungan." Borneo Engineering : Jurnal Teknik Sipil 3, no. 2 (January 5, 2020): 115–28. http://dx.doi.org/10.35334/be.v3i2.1173.
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The Kayan Watershed in Bulungan Regency is the largest river in North Kalimantan which has the potential for flooding in several irrigated points. Kayan River is a flood-prone area and prioritized to be handled immediately because there is already a smooth life for the community. Potentially need to know the great potential of flooding in the Kayan River. To find out the relationship between flood discharge and flood time, the Synthetic Unit Hydrograph calculation method is used. The aim is to determine the shape and results of peak discharge in Synthetic Unit Hydrograph Y (SUH). This study uses a debit calculation in the Kayan watershed using Snyder HSS a nd Nakayasu HSS. From the calculation results obtained Snyder SUH peak discharge of 118.0 m3/ sec at 73.85 hours, and Nakayasu SUH has a peak discharge of 109.35 m3 / sec at 54.09 hours.
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Yildirim, Sema, Hasan Erdinc Kocer, and Ahmet Hakan Ekmekci. "Quantitative Analysis of EEG Slow Wave Activity Based on MinPeakProminence Method." Traitement du Signal 38, no. 3 (June 30, 2021): 757–73. http://dx.doi.org/10.18280/ts.380323.
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Persistent, unchanging, and non-reactive focal or generalized abnormal Slow Wave (SW) activities in an awake adult patient are examined pathologically. Although these waves in Electroencephalogram (EEG) are much less prominent than transient activities in some areas, it is not possible to understand them easily by looking at the EEG. For this reason, reliable computer programs that can sort out Slow Waves (SWs) correctly are needed. In this study, a new method based on MinPeakProminence that can detect abnormal SW activities was developed. To test the performance of the study, the data collected from Selcuk University Hospital (22 subjects - epilepsy and various neurological diseases) and Bonn Hospital (only normal A dataset) were used. Various statistical performance measurement methods were used to search the results. The results of this analysis revealed that the classification success, sensitivity and specificity values obtained with the SUH dataset were 96.5%, 93.3% and 96.1%, respectively. In the results of the experiments made with the Bonn dataset, 100% classification success was achieved. Besides, according to the analyses, it was found that SWs are frequently seen in the posterior regions of the brain, especially in the parietal and occipital regions in the SUH dataset.
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Miranda, Juwita, SB Soeryamassoeka, and Danang Gunarto. "ANALYSIS OF FLOOD HYDROGRAPH IN THE LANDAK SUB WATERSHED." Jurnal Teknik Sipil 23, no. 3 (August 28, 2023): 406. http://dx.doi.org/10.26418/jts.v23i3.67407.
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This research is motivated by the natural flooding disaster in the Landak sub-watershed area, which can be caused by river overflow due to high rain intensity. Flood discharge can be calculated using the Synthetic Unit Hydrograph method if the available data is limited, such as only obtaining rainfall data and watershed characteristics.Several Synthetic Unit Hydrograph (SUH) methodologies, including SUH Snyder, Nakayasu, Soil Conservation Services (SCS), Gama I, ITB, and Limantara, were utilized in this study. The analyzed data included precipitation data and measured discharge data. Rainfall data are analyzed using the homogeneity test, statistical descriptors, and chi-squared to determine the planned flood discharge. Then, continue with the study of rainfall frequency and analysis of rainfall intensity so that the maximal discharge can be analyzed using three SUH methods: HSS Snyder, Nakayasu, and SCS. The analysis of measured release is conducted by statistically analyzing estimated discharge data.The analysis results are then compared to obtain the percentage error between the discharge plan and the minimum measured discharge. The results showed that the HSS Snyder method was selected for analyzing flood discharge in the Landak sub-watershed basin because it has the minimum percentage error from comparing planned release and measured discharge values. Therefore, for the calculation of flood discharge analysis of the Landak sub-watershed basin, the HSS Snyder method is used with the acquisition of flood discharge plans for the return period of 2, 5, 10, 20, 50, and 100 years of 648,880 m3/sec, 896,335 m3/sec, 1025,954 m3/sec, 1132,006 m3/sec, 1252,788 m3/sec, 1335,273 m3/sec.
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Buana, Hadi, Lily Montarcih Limantara, Pitojo Tri Juwono, and Moh Sholichin. "Time Lag Modeling in Modification of Nakayasu Synthetic Unit Hydrograph." Journal of Hunan University Natural Sciences 49, no. 7 (July 30, 2022): 9–17. http://dx.doi.org/10.55463/issn.1674-2974.49.7.2.
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In the development of the synthetic unit hydrograph method, the empirical formula expresses the relation between the watershed morphometry characteristic and the constituent elements of hydrographs that are peak discharge (Qp), time to peak (tp), time lag (TL), and time base (Tb). This research intends to build a model of time lag in order to modify the Nakayasu SUH modeling. The Nakayasu synthetic unit hydrograph (SUH) model, seen as very popular and widely used by practitioners, needs to be adjusted for the main parameters that form the hydrograph to be able to be directly used based on the watershed morphometry characteristic. Based on the specific characteristic of the Nakayasu SUH formulation, this research will focus on developing the Nakayasu SUH model by the modification with adding the watershed characteristic parameter to the time lag parameter (tL). This research was conducted in 23 watersheds in Indonesia. The previous research in the same watersheds indicates five morphometry parameters with a positive effect on the time lag with the ranking due to the strongest effect as follows: watershed area (A), the river length from outlet to the weight point of the watershed (Lc), H = L.Lc, and the main river length (L). However, the two other parameters negatively affect the time lag with the ranking due to the strongest effect as follows: river network density (D) and river slope (K). Then, the modeling of time lag is carried out based on the research result, and the result of the time lag model is as follows: tL=Lc0.1809H-0.00159A0.003459
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Kumari, Priyanka, and Sushil Kumar. "Estimation of Design Flood for Rivers of Saurashtra Region Contributing into the Gulf of Khambhat." Current World Environment 11, no. 3 (December 25, 2016): 869–82. http://dx.doi.org/10.12944/cwe.11.3.23.
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Design flood has been estimated for rivers of Saurashtra region contributing into the Gulf of Khambhat using deterministic as well as statistical approach for planning, design and management of hydraulic structures. By comparing the results obtained by these approaches, one can easily estimate the flow rate or peak discharge to a given design return period and can establish the suitability of approach for this study area. Nine river basins with 20 dams of Saurashtra region were analyzed in this study. Though Saurashtra is one of the most water scarce regions of India yet it suffers from the flooding problem, as the numbers of rainy days are very less and the rainfall intensity is very high. Due to being a regulated basin, dam wise study was preferred. Deterministic approach was carried out using synthetic unit hydrograph (SUH) and regional flood formulae (RFF) methods for subzone-3a provided in Central Water Commission (CWC) report, 2001. Statistical approach was carried out using Rainfall frequency analysis employingGumbel’s EV1distribution. As there is no spill by these hydraulic structures and the annual flood data for the nine river sites are heavily affected by the storage dams in the upstream. Hence these data violate the basic principle of virgin flow. Hence the analysis of these data was not attempted further. The main objective of study was to carry out the rainfall frequency analysis for these river basins to get 24 hour rainfall for a return period of 25, 50 and 100 years for an individual basin instead of using the value obtained by iso-pluvial map to estimate the design flood. The overall results reveals that due to construction of number of dams in 9 river basins, design flood estimation on each dam by using deterministic approach is more feasible.Revised design floods using SUH and RFF method on the basis of estimated rainfall indicates over-estimated and under-estimated design floods. Since the percentage difference is very less between revised SUH and revised RFF method. So, for safety purpose one with higher value should be used.
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SHEN, QIONG, WEN-TZONG LEE, KEVIN RUSSELL, and RAJ S. SODHI. "ON MOTION GENERATION OF WATT I MECHANISMS FOR MECHANICAL FINGER DESIGN." Transactions of the Canadian Society for Mechanical Engineering 32, no. 3-4 (September 2008): 411–22. http://dx.doi.org/10.1139/tcsme-2008-0027.
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This work formulates and demonstrates a motion generation method for the synthesis of a particular type of planar six-bar mechanism-the Watt I mechanism. The Watt I mechanism is essentially a “stacked” four-bar mechanism (having two closed loops and a single degree of freedom). Extending the planar motion generation method of Suh and Radcliffe [11] to incorporate relative motion between moving pivots, Watt I mechanisms are synthesized to simultaneously approximate two groups of prescribed rigid-body poses for simultaneous dual motion generation capability. The example included demonstrates the synthesis of a finger mechanism to achieve a prescribed grasping pose sequence.
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Cho, Hong-Yeon, Weon Mu Jeong, Ju Whan Kang, and Gi-Seop Lee. "Design Wave Period Estimation Using the Wave Height Information." Journal of Korean Society of Coastal and Ocean Engineers 35, no. 4 (August 31, 2023): 84–94. http://dx.doi.org/10.9765/kscoe.2023.35.4.84.
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The wave height and period regression curve is widely used to estimate the design wave period. In this study, the parameters of the curves are estimated, compared, and evaluated using the linear, robust linear, and nonlinear regression methods, respectively. The data used in the design wave height estimation are the annual maxima (AM) wave height and period data sets divided by typhoon and non-typhoon conditions, provided by the Ministry of Oceans and Fisheries (2019). The estimation parameters show significant differences in the local coastal waters and the estimation methods. The estimation parameters based on the Suh et al. (2008, 2010) method show the apparent bias, under-estimation in the intercept (scale) parameter, and over-estimation in the slope (exponent) parameter, respectively.
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Pramudya, Adlan Rafli, and Agung Sumarno. "Experimental Study of Utilization Coconut Fiber as Additional Material and Slag as a Cement Substitution Against Compressive Strength and Split Tensile Strength of Concrete." Neutron 22, no. 01 (July 31, 2022): 31–40. http://dx.doi.org/10.29138/neutron.v22i01.174.
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Development developments have an impact on the building materials industry sector. To reduce CO2 emissions due to soaring productivity of cement, the industry can use Ground Granulated Blast Furnace Slag (GGBFS) as a substitute for cement. This study aims to determine the effect of using GGBFS as a substitute for cement and coconut fiber as an additive on the workability, density, water absorption, compressive strength and split tensile strength of concrete at 3, 7, and 28 days. In this study using the experimental method with a total of 84 samples of cylindrical specimens with a size of 10cm x 20cm. This research was conducted with variations of GGBFS substitution of cement (0%, 35.5%, 43.5%) and coconut fiber as an additive (0.23%, 0.63%).The results of this study indicate that the optimum compressive strength test value at the age of 28 days is at GGBFS (35.5%) and coconut fiber (0.63%) reaches an average compressive strength of 32.32 Mpa. The SU1 variation (24.63 Mpa), SU2 variation (30.20 Mpa), SU3 variation (30.77 Mpa), SU5 variation (28.16 Mpa), SU6 variation (28.31 Mpa). Optimal splitting strength at the age of 28 days, namely the SU4 variation with GGBFS 35.5% and coconut fibers (0.63%) reached an average split tensile strength of 2.23 Mpa.
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Mustamin, Muhammad Rifaldi, Farouk Maricar, and Riswal Karamma. "Hydrological Analysis In Selecting Flood Discharge Method In Watershed Of Kelara River." INTEK: Jurnal Penelitian 8, no. 2 (December 20, 2021): 141. http://dx.doi.org/10.31963/intek.v8i2.2874.
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For Engineers involved in planning and construction of water resources building, hydrology becomes very important data. In terms of planning stage in water resources especially waterworks, it is known that design flood discharge closed to field realistic conditions is often needed in order that a planned construction is able to control flood discharge. Several previous researches in choosing flood discharge selection method have diverse depending on observed watershed. One method in determining selected flood discharge by verification using Creager diagram, by comparing discharge calculation results of several Synthetic Unit Hydrograph (SUH) with infrastructure flood discharge (AWLR result) in observation point. This research aims to obtain the most suitable synthetic unit hydrograph and close to analysis result of measured discharge frequency, and Creager diagram in Kelara watershed (DAS). Based on the calculation of design flood discharge according to rainfall data using synthetic unit hydrograph of Nakayasu, ITB I, ITB II, and SCS (HEC-HMS) as well as the calculation of design flood discharge according to collected data, it is concluded that the synthetic unit hydrograph method closest to design flood discharge with measured discharge rate and Q1000 rate of Creager diagram is SCS. Flood discharge rate obtained according to HSS SCS method using HEC-HMS 4.8 application in period of 2 years is 658,40 m3/s, 25 years is 682,70 m3/s, 50 years is 787,00 m3/s, 100 years is 885,70 m3/det, and 1000 years is 1202,60 m3/s
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Yi, Bin, Lu Chen, Hansong Zhang, Vijay P. Singh, Ping Jiang, Yizhuo Liu, Hexiang Guo, and Hongya Qiu. "A time-varying distributed unit hydrograph method considering soil moisture." Hydrology and Earth System Sciences 26, no. 20 (October 20, 2022): 5269–89. http://dx.doi.org/10.5194/hess-26-5269-2022.
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Abstract. The distributed unit hydrograph (DUH) method has been widely used for flow routing in a watershed because it adequately characterizes the underlying surface characteristics and varying rainfall intensity. Fundamental to the calculation of DUH is flow velocity. However, the currently used velocity formula assumes a global equilibrium of the watershed and ignores the impact of time-varying soil moisture content on flow velocity, which thus leads to a larger flow velocity. The objective of this study was to identify a soil moisture content factor, which, based on the tension water storage capacity curve, was derived to investigate the response of DUH to soil moisture content in unsaturated areas. Thus, an improved distributed unit hydrograph, based on time-varying soil moisture content, was obtained. The proposed DUH considered the impact of both time-varying rainfall intensity and soil moisture content on flow velocity, assuming the watershed to be not in equilibrium but varying with soil moisture. The Qin River basin and Longhu River basin were selected as two case studies, and the synthetic unit hydrograph (SUH), the time-varying distributed unit hydrograph (TDUH) and the current DUH methods were compared with the proposed method. Then, the influence of time-varying soil moisture content on flow velocity and flow routing was evaluated, and results showed that the proposed method performed the best among the four methods. The shape and duration of the unit hydrograph (UH) were mainly related to the soil moisture content at the initial stage of a rainstorm, and when the watershed was approximately saturated, the grid flow velocity was mainly dominated by excess rainfall. The proposed method can be used for the watersheds with sparse gauging stations and limited observed rainfall and runoff data.
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Bernard, Florent, Viktor Fischer, Crina Costea, and Robert Fouquet. "Implementation of Ring-Oscillators-Based Physical Unclonable Functions with Independent Bits in the Response." International Journal of Reconfigurable Computing 2012 (2012): 1–13. http://dx.doi.org/10.1155/2012/168961.
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The paper analyzes and proposes some enhancements of Ring-Oscillators-based Physical Unclonable Functions (PUFs). PUFs are used to extract a unique signature of an integrated circuit in order to authenticate a device and/or to generate a key. We show that designers of RO PUFs implemented in FPGAs need a precise control of placement and routing and an appropriate selection of ROs pairs to get independent bits in the PUF response. We provide a method to identify which comparisons are suitable when selecting pairs of ROs. Dealing with power consumption, we propose a simple improvement that reduces the consumption of the PUF published by Suh et al. in 2007 by up to 96.6%. Last but not least, we point out that ring oscillators significantly influence one another and can even be locked. This questions the reliability of the PUF and should be taken into account during the design.
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Petrovic, Ana, Sanja Manojlovic, and Stanimir Kostadinov. "How Extreme Were The Torrential Floods In Smaller Watersheds In Serbia In September 2014." Academic Perspective Procedia 4, no. 2 (November 6, 2021): 116–24. http://dx.doi.org/10.33793/acperpro.04.02.41.
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The September torrential floods in 2014 in the Eastern Serbia were a real disaster for local residents in municipalities of Kladovo, Negotin and Majdanpek. Meteorological extreme event caused the hydrological extreme event which led to declaration of the emergency situation in all three municipalities. The combined method of Soil Conservation Service and synthetic unit triangular hydrograph (SCS-SUH) is employed to compute the maximal discharges in small watersheds of Dupljanska reka and Manastiricki potok, in order to assess the extremeness of September 2014 torrential flood events. Since the surface runoff is accompanied by intensive soil erosion on watershed slopes and the maximal discharges by sediment transport in river beds, estimation of mean annual sediment transport is also presented in this work. The September 2014 floods will remain historic given that they took 5 human lives and caused enormous material damage for local municipalities, so presented hydrological analysis should be taken as very important part of flood event documentation along with reports of municipalities’ emergency headquarters.
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OH, YONG-GEUN, and RUI WANG. "ANALYSIS OF CONTACT CAUCHY–RIEMANN MAPS II: CANONICAL NEIGHBORHOODS AND EXPONENTIAL CONVERGENCE FOR THE MORSE–BOTT CASE." Nagoya Mathematical Journal 231 (May 15, 2017): 128–223. http://dx.doi.org/10.1017/nmj.2017.17.
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This is a sequel to the papers Oh and Wang (Real and Complex Submanifolds, Springer Proceedings in Mathematics and Statistics 106 (2014), 43–63, eds. by Y.-J. Suh and et al. for ICM-2014 satellite conference, Daejeon, Korea, August 2014; arXiv:1212.4817; Analysis of contact Cauchy–Riemann maps I: a priori$C^{k}$estimates and asymptotic convergence, submitted, preprint, 2012, arXiv:1212.5186v3). In Oh and Wang (Real and Complex Submanifolds, Springer Proceedings in Mathematics and Statistics 106 (2014), 43–63, eds. by Y.-J. Suh and et al. for ICM-2014 satellite conference, Daejeon, Korea, August 2014; arXiv:1212.4817), the authors introduced a canonical affine connection on $M$ associated to the contact triad $(M,\unicode[STIX]{x1D706},J)$. In Oh and Wang (Analysis of contact Cauchy–Riemann maps I: a priori$C^{k}$estimates and asymptotic convergence, submitted, preprint, 2012, arXiv:1212.5186v3), they used the connection to establish a priori$W^{k,p}$-coercive estimates for maps $w:\dot{\unicode[STIX]{x1D6F4}}\rightarrow M$ satisfying $\overline{\unicode[STIX]{x2202}}^{\unicode[STIX]{x1D70B}}w=0$, $d(w^{\ast }\unicode[STIX]{x1D706}\circ j)=0$without involving symplectization. We call such a pair $(w,j)$ a contact instanton. In this paper, we first prove a canonical neighborhood theorem of the locus $Q$ foliated by closed Reeb orbits of a Morse–Bott contact form. Then using a general framework of the three-interval method, we establish exponential decay estimates for contact instantons $(w,j)$ of the triad $(M,\unicode[STIX]{x1D706},J)$, with $\unicode[STIX]{x1D706}$ a Morse–Bott contact form and $J$ a CR-almost complex structure adapted to $Q$, under the condition that the asymptotic charge of $(w,j)$ at the associated puncture vanishes.We also apply the three-interval method to the symplectization case and provide an alternative approach via tensorial calculations to exponential decay estimates in the Morse–Bott case for the pseudoholomorphic curves on the symplectization of contact manifolds. This was previously established by Bourgeois (A Morse–Bott approach to contact homology, Ph.D. dissertation, Stanford University, 2002) (resp. by Bao (On J-holomorphic curves in almost complex manifolds with asymptotically cylindrical ends, Pacific J. Math. 278(2) (2015), 291–324)), by using special coordinates, for the cylindrical (resp. for the asymptotically cylindrical) ends. The exponential decay result for the Morse–Bott case is an essential ingredient in the setup of the moduli space of pseudoholomorphic curves which plays a central role in contact homology and symplectic field theory (SFT).
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Sharma, Jaswinder, and Jianlin Li. "A Low Cost and Scalable Approach for Coating Cathode Materials." ECS Meeting Abstracts MA2022-02, no. 6 (October 9, 2022): 615. http://dx.doi.org/10.1149/ma2022-026615mtgabs.
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High voltage (e.g., LNMO) and high capacity (e.g., NMC) cathode materials are highly desirable for achieving high energy density batteries. However, most of these cathode materials participate in parasitic reactions with electrolyte components. These reactions decrease the cyclic stability and capacity of these cathode materials, and thus lower their attractiveness. These parasitic reactions can be minimized by applying a thin coating of oxide materials such as silica or zirconia. Silica coating on cathode materials is highly desirable because of its low cost and high electrochemical stability. Several methods including ball milling of silica particles with cathode powder, sol-gel deposition of silica using protic solvents (e.g., ethanol and ammonium hydroxide) has been explored. However these methods have their own limitations, for example, ball milling based method provides incomplete coating formation, and the use of protic solvents such as ethanol and ammonium hydroxide in sol-gel silica deposition results in leaching of Li+ ions out of the cathode materials. Leaching of Li+ out of cathode particles results in lowered capacity of coated cathode materials. Therefore obtained coated cathode materials generally have a lower capacity than the uncoated cathode materials. Therefore, there is a need of a low cost method that provides a uniform coating but without leaching out the Li+ ions or compromising with the mechanical integrity of the cathode particles. In the present work, we demonstrate a low cost and scalable method that provides very thin coatings of oxide materials but without compromising with the capacity and mechanical properties of the cathode material. Coating presence was confirmed by using transmission electron microscope (TEM), energy dispersive X-rays (EDX), and X-ray photoelectron spectroscopy (XPS). Preliminary, results showed that the cells having coated cathodes have better cyclic stability when compared to the cells made of uncoated cathode materials. This research is funded by DOE’s Vehicle Technologies Office by Program Manager Dr. Changwon Suh.
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SHAH, AJIT. "The importance of the socioeconomic status of countries for mental disorders in old age: development of an epidemiological transition model." International Psychogeriatrics 19, no. 4 (May 16, 2007): 785–87. http://dx.doi.org/10.1017/s1041610207005479.
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The prevalence of a disorder is a function of the incidence of the disorder and the duration of the illness (which may remit spontaneously, by treatment or death). The socioeconomic status of societies may influence the incidence and duration of mental illnesses in old age by influencing life expectancy and availability of appropriate healthcare services and treatments (Suh and Shah, 2001). The relationship between a proxy measure of the socioeconomic status (per capita gross national domestic product (GDP)) and (i) the life expectancy, (ii) child mortality rates and (iii) proxy measures of the quality and quantity of available healthcare services (the proportion of GDP spent on health, per capita expenditure on health and child mortality rates) was examined. The WHO website (www.who.int/countries/en/) provided data on these variables for 191 of the 192 countries for the year 2002. The inter-correlations between all the measured variables were examined using Pearson's correlation coefficient. Because of highly significant inter-correlations between all these variables, multiple linear regression analysis, with the Enter method, was undertaken with per capita GDP as the dependent variable, and all the variables that were significantly correlated with per capita GDP on univariate analysis as the independent variables.
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Tymchuk, D. S., G. S. Potapenko, N. F. Tymchuk, and I. K. Kuznetsova. "Combining ability of corn inbreds – carriers of mutations Su1 and Su2 on the content of oleic acid glycerides." Faktori eksperimental'noi evolucii organizmiv 29 (August 31, 2021): 47–51. http://dx.doi.org/10.7124/feeo.v29.1405.
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Aim. Evaluation of donors’ properties of corn inbreds - carriers of endospermic mutations su1 and su2 on the oleates content. Methods. A series of hybrids obtained in top- crosses of 10 inbreds of the common type with four testers – low-oleic and high-oleic inbreds of the common type and inbreds – carriers of the su1 and su2 mutations were analyzed. Oleates’s content was determined by the gas chromatographic method. Results. The highest effects of the general combining ability were shown by the inbreds obtained from high-oil synthetics and the inbreds - carriers the su1 and su2 mutations. Hybrids of low-oleic inbreds with the sources of su1 and su2 mutations had an increased content of oleates in comparison with maternal forms, and hybrids of high-oleic inbreds with the sources of these mutations inherited the oleates content in an intermediate type. In F2 hybrids from crosses of inbreds of the common type with the inbreds - carriers of the su1 and su2 mutations, transgressions were observed. Conclusions. The increased content of oleates in corn inbreds inbreds and hybrids is most likely controlled by oleate - coding loci of chromosome 4 and 6 linked to mutant genes su1 and su2. The carriers of these genes can be used as sources of increased oleate content in the corn breeding for oil quality.
Key words: Zea mays L., endospermic mutants, oleates content, top-crosses
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Iis Rahayu, Erwin Syahputra, and Anita Sumelvia Dewi. "Pengaruh Lingkungan Kerja Fisik Dan Komunikasi Terhadap Kinerja Pegawai Di UPTD Puskesmas Pesantren I Kediri." Akuntansi 1, no. 3 (September 1, 2022): 15–30. http://dx.doi.org/10.55606/jurnalrisetilmuakuntansi.v1i3.37.
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This study aim to explain the significant influence between physical work environment and communication on employee performance at UPTD Puskesmas Pesantren I Kediri. The sampel in this study was 36 respondents with a sampling method using purposive sampling technique in which the determination of the number of samples with ertain considerations, namely the criteria of civil servants. The data analysis technique used in this research is instrument validity test, instrument reliabiity test, multiple linear regression test, classical assumption test and partial hypothesis testing which is tested by t test while the simultaneous hypothesis is tested by F test. The result of the study show that the physical work environment partially has a significant influence on the performance of employees at the UPTD Puskesmas Pesantren I Kediri. Communication partially has a significant effect on the performance of employees at the UPTD Puskesmas Pesantren I Kediri. The physical work environment and communication simultaneously have a significant influence on employee performance at the UPTD Puskesmas Pesantren I Kediri. In addition, the coefficient of determination (R2) is 0.397 or 39.7%. This indicates that the performance of the employees of UPTD Puskesmas Pesantren I Kediri is influenced by the physical work environment and communication variables by 39.7%. While the remaining 60.3% came from other variables obtained from previous studies suh as motivation and discipline which were not included in this study.
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Suh, Jung-Soo, and Tae-Jin Kim. "Abstract 5617: A novel DNA double-strand breaks biosensor based on fluorescence resonance energy transfer." Cancer Research 83, no. 7_Supplement (April 4, 2023): 5617. http://dx.doi.org/10.1158/1538-7445.am2023-5617.
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Abstract Revealing the spatiotemporal behavior of DNA double-strand breaks (DSBs) is crucial for understanding the processes of DNA damage and repair. Traditionally, γH2AX and DNA damage response (DDR) factors have been used to detect DSBs using classical biochemical assays, such as antibody-based immunostaining. However, a reliable method to visualize and assess DSB activity real-time in living cells is yet to be established. Herein, we developed a novel DNA double-strand breaks biosensor (DSBS) based on fluorescence resonance energy transfer (FRET) by employing the H2AX and BRCT1 domains. By applying FRET imaging with DSBS, we show that DSBS specifically reacts to drug- or ionizing radiation (IR)-induced γH2AX activity, allowing for the quantification of DSB events at high spatiotemporal resolutions. Taken together, we provide a new experimental tool to evaluate the spatiotemporal dynamics of DNA double-strand breaks in response to cancer therapies. Ultimately, our biosensor can be useful for elucidating the molecular mechanisms underlying DNA damage and repair processes and applying for cancer therapies. Citation Format: Jung-Soo Suh, Tae-Jin Kim. A novel DNA double-strand breaks biosensor based on fluorescence resonance energy transfer. [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 5617.
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Ramadhani, Faza. "Dependable Flow and Flood Control Performance of Logung Dam, Central Java Province, Indonesia." Journal of the Civil Engineering Forum 3, no. 2 (September 12, 2017): 343. http://dx.doi.org/10.22146/jcef.26636.
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The change of land use in Mt. Muria area Central Java has been resulting in the significant sheet erosion of upstream watershed around Mt. Muria, followed by considerably high sedimentation on rivers downstream that lead to the reduction of cross sections of the rivers including Logung River. Such situation has been contributing the condition that downstream of Logung River is very potential to experience over flow and inundation to its surrounding area. An idea of constructing the Logung Dam was introduced in 1986 that aimed at reducing the aforementioned inundation. Besides, the development of Logung Dam was also aimed at fulfilling both irrigation and non-irrigation water demand. This paper presents the results of the analysis of the water availability and flood control performance of the Logung Dam. The dependable flow was analyzed by applying the National Rural Electric Cooperative Association (NRECA) method in order to determine the low flow characteristics, whereas the identification of the high flow characteristics was carried out by using the Synthetic Unit Hydrograph (SUH) methods, i.e., the GAMA I and Nakayasu modeling approach. At a certain reservoir characteristic and a defined geometry of spillway, several reservoir routing simulations were carried out on both dependable flows and high flows. Results of the reservoir routing showed the promising water availability of the Logung Dam to fulfill water demand for both irrigation and non-irrigation, whereas the reservoir routing could reduce the probable maximum flood from QPMF from 1,031 m3/s to approximately 950 m3/s or damping efficiency at 7.86%. Further analysis suggests necessary operation and maintenance of Logung Dam to sustain its function and to mitigate possible problems related to reservoir sedimentation.
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Mendes, Elsa Palma, Hajra Okhai, Rilda Epifânia Cristóvão, Maria Cecília Almeida, Nzuzi Katondi, Ricardo Thompson, Sylvain Mupoyi, et al. "Mapping of schistosomiasis and soil-transmitted helminthiases across 15 provinces of Angola." PLOS Neglected Tropical Diseases 16, no. 6 (June 30, 2022): e0010458. http://dx.doi.org/10.1371/journal.pntd.0010458.
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Introduction Schistosomiasis (SCH) and soil transmitted helminthiases (STH) have been historically recognized as a major public health problem in Angola. However, lack of reliable, country wide prevalence data on these diseases has been a major hurdle to plan and implement programme actions to target these diseases. This study aimed to characterize SCH and STH prevalence and distribution in Angola. Methods A country wide mapping was conducted in October 2018 (1 province) and from July to December 2019 (14 provinces) in school aged (SAC) children in 15 (of 18) provinces in Angola, using WHO protocols and procedures. A total of 640 schools and an average of 50 students per school (N = 31,938 children) were sampled. Stool and urine samples were collected and processed using the Kato-Katz method and Urine Filtration. Prevalence estimates for SCH and STH infections were calculated for each province and district with 95% confidence intervals. Factors associated with SCH and STH infection, respectively, were explored using multivariable logistic regression accounting for clustering by school. Results Of the 131 districts surveyed, 112 (85.5%) are endemic for STH, 30 (22.9%) have a prevalence above 50%, 24 (18.3%) are at moderate risk (prevalence 20%-50%), and 58 (44.3%) are at low risk (<20% prevalence); similarly, 118 (90,1%) of surveyed districts are endemic for any SCH, 2 (1.5%) are at high risk (>50% prevalence), 59 (45.0%) are at moderate risk (10%-50% prevalence), and 57 (43.5%) are at low risk (<10% prevalence). There were higher STH infection rates in the northern provinces of Malanje and Lunda Norte, and higher SCH infection rates in the southern provinces of Benguela and Huila. Conclusions This mapping exercise provides essential information to Ministry of Health in Angola to accurately plan and implement SCH and STH control activities in the upcoming years. Data also provides a useful baseline contribution for Angola to track its progress towards the 2030 NTD roadmap targets set by WHO.
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Gustama, Gustama, Fadillah Sabri, and Donny Fransiskus Manalu. "KESESUAIAN HIDROGRAF SATUAN SINTETIK TERHADAP HIDROGRAF SATUAN TERUKUR(STUDI KASUS SUB SUB DAERAH ALIRAN SUNGAI PEDINDANG BAGIAN TENGAH)." FROPIL (Forum Profesional Teknik Sipil) 6, no. 1 (June 7, 2018): 29–44. http://dx.doi.org/10.33019/fropil.v6i1.1263.
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A widely used method for analyzing river flow for flood forecasts is hydrograph unit. The hydrograph unit is a direct runoff hydrograph that can be created when there are AWLR record data, debit measurements and rainfall data. Synthetic Unit Hydrograph (SUH) is a unit hydrograph derived based on river data in the same watershed or nearby watershed but has the same characteristics, ie HSS Gama I, HSS Nakayasu, Limasan HSS, HSS Snyder and HSS SCS. Of the two hydrographs, there will be suitability of the hydrograph form that is going to be made. Sub territory of Pedindang River Basin has four flood incidents, namely, date 23-24 February 2016; March 2-3, 2016; March 3-4, 2016; and date 5-6 March 2016. In the analysis of each flood event, the peak discharge of synthetic unit hydrograph is very different from the peak discharge of the measured unit hydrograph. The average peak discharge of synthetic unit hydrograph occurs in the range of 2 or 3 hours, while the measured unit hydrograph of Pedindang River occurs in the range of 7 or 8 hours. In four flood events it is stated that, HSS Gama I approaches RMSE value (validation <10%) to HST form of Pedindang River with value: RMSE incidence I (23,601%); RMSE incidence II (16.315%); RMSE incidence III (50,400%); RMSE incidence IV (22.322%). With this result, it is stated that there is no synthetic unit hydrograph model that has compatibility with the measured unit hydrograph of Pedindang River.
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Schuss, Patrick, Jürgen Konczalla, Johannes Platz, Hartmut Vatter, Volker Seifert, and Erdem Güresir. "Aneurysm-related subarachnoid hemorrhage and acute subdural hematoma: single-center series and systematic review." Journal of Neurosurgery 118, no. 5 (May 2013): 984–90. http://dx.doi.org/10.3171/2012.11.jns121435.
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Object Subarachnoid hemorrhage (SAH) with simultaneous acute subdural hematoma (SDH) is a severe disease. The authors' objective was to analyze the incidence, prognosis, and clinical outcome of patients suffering from aneurysm-related SAH and space-occupying acute SDH. Methods Between June 1999 and June 2011, data from 989 patients with aneurysm-related SAH were prospectively entered into a database. Eighteen patients (1.8%) presented with aneurysm-related SAH and space-occupying acute SDH. The treatment decision (clip or coil) was based on an interdisciplinary approach. Outcome was assessed according to the modified Rankin Scale (mRS) at 6 months and was dichotomized into favorable outcome (mRS Score 0–2) versus unfavorable outcome (mRS Score 3–6). PubMed was searched for published studies of aneurysm-related SAH and acute SDH to gain a larger population. A multivariate regression analysis was performed on the pooled data. Results Literature data, including the current series, revealed a total of 111 patients. Overall, 38 (34%) of 111 patients with aneurysm-related SAH and acute SDH achieved favorable outcome. Favorable outcome was achieved in 68% of patients with good-grade clinical presentation on admission (Hunt and Hess Grades I–III) versus 23% of the patients with poor-grade presentation (Hunt and Hess Grades IV and V, p < 0.0001). In the multivariate analysis, poor clinical condition at admission was the only predictor for unfavorable outcome (p = 0.02). Conclusions The present data confirm that patients with aneurysm-related SAH and acute SDH, even when presenting in poor clinical condition, might achieve favorable outcome. Therefore, treatment of patients with SAH and acute SDH should not be discontinued, but careful individual decision making is necessary for each patient.
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Waizel, Maria, Margarita G. Todorova, Sara Kazerounian, Annekatrin Rickmann, Björn R. Blanke, and Peter Szurman. "Efficacy of Vitrectomy Combined with Subretinal Recombinant Tissue Plasminogen Activator for Subretinal versus Subpigment Epithelial versus Combined Hemorrhages." Ophthalmologica 236, no. 3 (2016): 123–32. http://dx.doi.org/10.1159/000449172.
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Background: The aim of this study was to compare the outcomes after subretinal recombinant tissue plasminogen activator (rtPA) treatment for subretinal hemorrhages (SRH), subpigment epithelial hemorrhages (SPH), and combined subretinal and subpigment epithelial hemorrhages (CH). Methods: An observational analysis of patients treated with subretinal rtPA was performed. The primary endpoint was the assessment of visual improvement (best-corrected visual acuity, BCVA) after surgery. Secondary endpoints were evaluation of the maximal hemorrhage diameter (MHD) and central macular thickness (CMT) measured by spectral domain optical coherence tomography. Results: From a total of 83 eyes included in the study, 19 eyes showed SRH, 11 eyes SPH, and 53 eyes CH. For SRH and CH, the mean BCVA, MHD, and CMT improved significantly (p < 0.05). For patients with SPH, both the mean MHD and CMT decreased significantly (p < 0.05), whereas the mean BCVA improved only slightly after surgery (p = 0.28). Conclusion: Vitrectomy combined with subretinal rtPA injection and gas or air tamponade has a strong functional and anatomical effect on both SRH and CH and also seems to slightly improve the anatomical outcome in SPH.
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Chen, Ying-Chu, Yen-Feng Wang, Jie-Yuan Li, Shih-Pin Chen, Jiing-Feng Lirng, Shu-Shya Hseu, Hsin Tung, Po-Lin Chen, Shuu-Jiun Wang, and Jong-Ling Fuh. "Treatment and prognosis of subdural hematoma in patients with spontaneous intracranial hypotension." Cephalalgia 36, no. 3 (May 5, 2015): 225–31. http://dx.doi.org/10.1177/0333102415585095.
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Objective The objective of this article is to elucidate the outcome, prognostic predictors and timing of surgical intervention for subdural hematoma (SDH) in patients with spontaneous intracranial hypotension (SIH). Methods Patients with SDH were identified retrospectively from 227 consecutive SIH patients. Data were collected on demographics, clinical courses, neuroimaging findings, and treatment of SDH, which was later divided into conservative treatment, epidural blood patches (EBP), and surgical intervention. Poor outcome was defined as severe neurological sequelae or death. Results Forty-five patients (20%) with SDH (mean maximal thickness 11.9 ± 6.2 mm) were recruited. All 15 patients with SDH <10 mm achieved good outcomes by either conservative treatment or EBP. Of 30 patients with SDH ≥10 mm, patients with uncal herniation ( n = 3) had poor outcomes, even after emergent surgical evacuation ( n = 2), compared to those without ( n = 27) (100% vs. 0%, p < 0.001). Fourteen patients underwent surgical evacuation, resulting in good outcomes in all 12 who received early intervention and poor outcomes in the remaining two who received delayed intervention after Glasgow Coma Scale (GCS) score ≤8 (100% vs. 0%, p = 0.01). Conclusions Uncal herniation results in poor outcomes in patients with SIH complicated with SDH. In individuals with SDH ≥10 mm and decreased GCS scores, early surgical evacuation might prevent uncal herniation.
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TEMİZ, Hakan. "Automatic and Accurate Classification of Hotel Bathrooms from Images with Deep Learning." Uluslararası Muhendislik Arastirma ve Gelistirme Dergisi 14, no. 3 (December 31, 2022): 211–18. http://dx.doi.org/10.29137/umagd.1217004.
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Hotel bathrooms are one of the most important places in terms of customer satisfaction, and where the most complaints are reported. To share their experiences, guests rate hotels, comment, and share images of their positive or negative ratings. An important part of the room images shared by guests is related to bathrooms. Guests tend to prove their satisfaction or dissatisfaction with the bathrooms with images in their comments. These Positive or negative comments and visuals potentially affect the prospective guests. In this study, two different versions of a deep learning algorithm were designed to classify hotel bathrooms as satisfactory (good) or unsatisfactory (bad, when any defects such as dirtiness, deficiencies, malfunctions were present) by analyzing images. The best-performer between the two models was determined as a result of a series of extensive experimental studies. The models were trained for each of 144 combinations of 5 hyper-parameter sets with a data set containing more than 11 thousand bathroom images, specially created for this study. The “HotelBath” data set was shared also with the community with this study. Four different image sizes were taken into consideration: 128, 256, 512 and 1024 pixels in both directions. The classification performances of the models were measured with several metrics. Both algorithms showed very attractive performances even with many combinations of hyper-parameters. They can classify bathroom images with very high accuracy. Suh that the top algorithm achieved an accuracy of 92.4% and an AUC (area under the curve) score of 0.967. In addition, other metrics also proved the success of the algorithm. The proposed method can allow the rapid, accurate and automatic detection of such undesired circumstances in hotel bathrooms from images. Such a detection system can allow hotel management to take necessary actions quickly to remedy such unsatisfactory cases.
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Martini, Ross P., Jonathan Ward, Dominic A. Siler, Jamie M. Eastman, Jonathan W. Nelson, Rohan N. Borkar, Nabil J. Alkayed, Aclan Dogan, and Justin S. Cetas. "Genetic variation in soluble epoxide hydrolase: association with outcome after aneurysmal subarachnoid hemorrhage." Journal of Neurosurgery 121, no. 6 (December 2014): 1359–66. http://dx.doi.org/10.3171/2014.7.jns131990.
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Object Patients with aneurysmal subarachnoid hemorrhage (SAH) are at high risk for delayed cerebral ischemia (DCI) and stroke. Epoxyeicosatrienoic acids (EETs) play an important role in cerebral blood flow regulation and neuroprotection after brain injury. Polymorphisms in the gene for the enzyme soluble epoxide hydrolase (sEH), which inactivates EETs, are associated with ischemic stroke risk and neuronal survival after ischemia. This prospective observational study of patients with SAH compares vital and neurologic outcomes based on functional polymorphisms of sEH. Methods Allelic discrimination based on quantitative real-time polymerase chain reaction was used to differentiate wild-type sEH from K55R heterozygotes (predictive of increased sEH activity and reduced EETs) and R287Q heterozygotes (predictive of decreased sEH activity and increased EETs). The primary outcome was new stroke after SAH. Secondary outcomes were death, Glasgow Outcome Scale score, and neurological deterioration attributable to DCI. Results Multivariable logistic regression models adjusted for age at admission and Glasgow Coma Scale scores revealed an increase in the odds of new stroke (OR 5.48 [95% CI 1.51–19.91]) and death (OR 7.52 [95% CI 1.27–44.46]) in the K55R group, but no change in the odds of new stroke (OR 0.56 [95% CI 0.16–1.96]) or death (OR 3.09 [95% CI 0.51–18.52]) in patients with R287Q genotype, compared with wild-type sEH. The R287Q genotype was associated with reduced odds of having a Glasgow Outcome Scale score of ≤ 3 (OR 0.23 [95% CI 0.06–0.82]). There were no significant differences in the odds of neurological deterioration due to DCI. Conclusions Genetic polymorphisms of sEH are associated with neurological and vital outcomes after aneurysmal SAH.
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Saway, Brian Fabian, Tristan Fielder, Mohammed Abdul Alshareef, Habib Emil Rafka, Mithun Sattur, and Jonathan Lena. "Infratentorial retroclival and tentorial subdural hematoma from posterior communicating artery aneurysm rupture: A case report and systematic review of literature." Surgical Neurology International 13 (October 28, 2022): 499. http://dx.doi.org/10.25259/sni_758_2022.
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Background: The objective of this systematic review is to evaluate the pathogenesis, clinical course, and prognosis of patients who suffer from aneurysm rupture, leading to subdural hematoma (SDH) of the infratentorial space without associated subarachnoid hemorrhage (SAH). Methods: Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, a literature review was conducted in PubMed and Scopus electronic databases for relevant published cases of aneurysmal SDH (AnSDH) of the infratentorial compartment without associated SAH. The presentation, treatment, clinical course, and outcome of identified cases are compiled. In addition, a patient suffering from an infratentorial SDH following aneurysm rupture is presented with an illustrative case. Results: Three articles were identified and met inclusion criteria. All cases occurred from ruptured posterior communicating artery aneurysms. All patients arrived with a Hunt and Hess classification of 2 or less. Only one case was managed with operative aneurysm clipping and hematoma evacuation while the other three cases were managed endovascularly. There were no reported postoperative complications, vasospasm, or seizures reported. All patients had a final Modified Rankin score of 3 or less at last reported follow-up. Conclusion: Infratentorial AnSDH without associated SAH is an etiology rarely reported in the literature. Here, we present a case report and systematic review demonstrating a relatively benign clinical course and outcome compared to report aneurysm rupture associated with SAH or mixed SAH and SDH. Moreover, there appear to be lower rates of vasospasm and improved outcomes in patients with isolated AnSDH compared to the literature aneurysmal SAH rates.
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Narvid, Jared, Matthew R. Amans, Daniel L. Cooke, Steven W. Hetts, William P. Dillon, Randall T. Higashida, Christopher F. Dowd, and Van V. Halbach. "Spontaneous retroclival hematoma: a case series." Journal of Neurosurgery 124, no. 3 (March 2016): 716–19. http://dx.doi.org/10.3171/2015.2.jns142221.
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OBJECT Retroclival hematomas are rare, appearing mostly as posttraumatic phenomena in children. Spontaneous retroclival hematoma (SRH) in the absence of trauma also has few descriptions in the literature. None of the reported clinical cases features the combination of an SRH and intraventricular hemorrhage (IVH). Nevertheless, despite extensive cases of idiopathic or angiographically negative subarachnoid hemorrhage (SAH) of the posterior fossa, only a single case report of a patient with a unique spontaneous retroclival hematoma has been identified. In this study, the authors reviewed the presentation, management, and clinical outcome of this rare entity. METHODS The authors performed a retrospective analysis of all patients with diagnosed SRH at their institution over a 3-year period. Collected data included clinical history, laboratory results, treatment, and review of all imaging studies performed. RESULTS Four patients had SRH. All were appropriately evaluated for coagulopathic and/or traumatic etiologies of hemorrhage, though no etiology could be found. Moreover, all of the patients demonstrated SRH that both clearly crossed the basioccipital synchondrosis and was contained within a nondependent configuration along the retroclival dura mater. CONCLUSIONS Spontaneous retroclival hematoma, often associated with IVH, is a rare subtype of intracranial hemorrhage frequently recognized only when MRI demonstrates compartmentalization of the posterior fossa hemorrhage. When angiography fails to reveal an underlying lesion, SRH patients, like patients with traditional angiographically negative SAH, enjoy a remarkably good prognosis.
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Sakai, Yuzuru. "CM-JP-1 Structural Analysis using SPH Method." Proceedings of Mechanical Engineering Congress, Japan 2012 (2012): _CM—JP—1–1—_CM—JP—1–1. http://dx.doi.org/10.1299/jsmemecj.2012._cm-jp-1-1.
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Neumann, Ignacio, Ariel Izcovich, Ricardo Aguilar, Guillermo León Basantes, Patricia Casais, Cecilia C. Colorio, María Cecilia Guillermo Esposito, et al. "ASH, ABHH, ACHO, Grupo CAHT, Grupo CLAHT, SAH, SBHH, SHU, SOCHIHEM, SOMETH, Sociedad Panameña de Hematología, SPH, and SVH 2021 guidelines for management of venous thromboembolism in Latin America." Blood Advances 5, no. 15 (August 10, 2021): 3032–46. http://dx.doi.org/10.1182/bloodadvances.2021004267.
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Background: Venous thromboembolism (VTE) is a common disease in Latin American settings. Implementing international guidelines in Latin American settings requires additional considerations. Objective: The purpose of our study was to provide evidence-based guidelines about managing VTE for Latin American patients, clinicians, and decision makers. Methods: We used the Grading of Recommendations, Assessment, Development and Evaluation (GRADE)-ADOLOPMENT method to adapt recommendations from 2 American Society of Hematology (ASH) VTE guidelines (Treatment of VTE and Anticoagulation Therapy). ASH and local hematology societies formed a guideline panel comprised of medical professionals from 10 countries in Latin America. Panelists prioritized 18 questions relevant for the Latin American context. A knowledge synthesis team updated evidence reviews of health effects conducted for the original ASH guidelines and summarized information about factors specific to the Latin American context (ie, values and preferences, resources, accessibility, feasibility, and impact on health equity). Results: The panel agreed on 17 recommendations. Compared with the original guideline, 4 recommendations changed direction and 1 changed strength. Conclusions: This guideline adolopment project highlighted the importance of contextualization of recommendations suggested by the changes to the original recommendations. The panel also identified 2 implementation priorities for the region: expanding the availability of home treatment and increasing the availability of direct oral anticoagulants (DOACs). The guideline panel made a conditional recommendation in favor of home treatment for individuals with deep venous thrombosis and a conditional recommendation for either home or hospital treatment for individuals with pulmonary embolism. In addition, a conditional recommendation was made in favor of DOACs over vitamin K antagonists for several populations.
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Năstăsescu, Vasile. "FEM or SPH ?" Journal of Engineering Sciences and Innovation 1, no. 1 (August 30, 2016): 34–48. http://dx.doi.org/10.56958/jesi.2016.1.1.34.
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This paper brings, in front of the reader, some aspects regarding the using of those numerical methods, perhaps most used, for analysis of the fluids and structures. Next to the FEM (Finite Element Method), new numerical methods appeared, among these, the methods named meshfree methods are nowadays most used. The SPH (Smoothed Particle Hydrodynamics) method belongs to this category of meshfree method, being the most used in different fields like astrophysical phenomena, fluid dynamics, structure dynamics and others. The paper put face to face some results obtained by FEM and SPH, so the reader can alone to appreciate which method is better in a given problem or other. For to facilitate analysis and to understand the results, the fundamentals of SPH method are presented. In contrast to FEM, the SPH method is less known and less used in Romania. This finding underlies the emergence of this article. The answer to the title question depends on every one and it is influenced by many factors. Finally, the author suggests an answer by a correction of the title question: FEM and SPH or FEM with SPH.
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Polkovnikov, O. Yu, V. I. Pertsov, М. V. Yeleynyk, and N. V. Izbytska. "Disturbances of cerebrospinal fluid dynamics as a complication of aneurysmal subarachnoid hemorrhage: predictors of development and influence of aneurysm occlusion method on the development of shunt-dependent hydrocephalus." Ukrainian Interventional Neuroradiology and Surgery 37, no. 3 (February 3, 2022): 62–68. http://dx.doi.org/10.26683/2786-4855-2021-3(37)-62-68.
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Objective ‒ to study the effect of ruptured aneurysm localization, severity of hemorrhage and aneurysm occlusion method on the probability of developing shunt-dependent hydrocephalus (SDH) and to assess the prognostic sensitivity of clinical and radiological scales.Materials and methods. The results of treatment of 597 patients with aneurysmal subarachnoid hemorrhage (SAH) of varying severity were analyzed. In 282 cases endovascular occlusion of the aneurysm was performed, in 315 ‒ microsurgical clipping. A group of 63 patients who required implantation of the ventriculoperitoneal shunt system within 3 to 15 weeks after aneurysm rupture was selected.Results. Of the patients who underwent coiling of the ruptured aneurysm, 22 (7.8 %) required implantation of the cerebrospinal fluid shunt system, and 41 (13.0 %) of the patients who underwent microsurgery. The mean age of patients in the endovascular occlusion group was 64.28 years, in the microsurgical clipping group ‒ 50.64 years. The localization was dominated by aneurysms of the anterior communicating artery (ACA) complex ‒ 37 (58.7 %) observations, internal carotid artery ‒ 15 (23.8 %), vertebrobasilar basin (VBB) ‒ 9 (14.3 %) and the middle cerebral artery ‒ 2 (3.2 %). The predominance of aneurysms of the ACA complex among those operated by microsurgical method (29 (70.7 %)) and VBB aneurysms among those operated on endovascularly (9 (40.9 %)) was revealed. Rupture of the aneurysm was complicated by massive SAH in 20 (31.7 %) cases, subarachnoid-parenchymal hemorrhage ‒ in 7 (11.1 %), subarachnoid-ventricular ‒ in 4 (6.4 %), subarachnoid-parenchymal-ventricular ‒ in 32 (50.8 %). The distribution by severity of hemorrhage on the Hunt‒Hess scale was as follows: grade II ‒ 10 (15.9 %) cases, grade III ‒ 26 (34.9 %), grade IV ‒ 27 (49.2 %). According to the Fisher radiological scale, grade III hemorrhage was noted in 20 (31.7 %) cases, IV ‒ in 43 (68.3 %) cases. Analysis using the Graeb scale showed the absence of blood in the ventricular system in 27 (42.9 %) cases, 1‒3 points ‒ in 9 (14.3 %), 4‒6 points ‒ in 12 (19.0 %), 7–12 points ‒ in 15 (28.8 %).Conclusions. Rupture of aneurysms of the ACA complex, accompanied by severe complicated SAH in patients operated on by microsurgery, and aneurysms of the VBB in persons operated on endovascularly, increases the risk of SDH. Endovascular occlusion of ruptured aneurysms does not increase the risk of SDH. The severity of hemorrhages of III–IV degree on the Hunt‒Hess scale and III–IV degree on the Fisher scale are predictors of SDH development.
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Fergie, Jaime, Tara Gonzales, Mina Suh, Xiaohui Jiang, Jon Fryzek, Ashley Howard, and Adam Bloomfield. "1513. Medically Attended Respiratory Syncytial Virus Hospitalizations (RSVH) and All-Cause Bronchiolitis Hospitalizations (BH) Among Children Aged ≤ 24 Months at RSV Season Start With Higher-Risk Congenital Heart Disease (CHD) Before and After the 2014 American Academy of Pediatrics (AAP) Policy." Open Forum Infectious Diseases 7, Supplement_1 (October 1, 2020): S760. http://dx.doi.org/10.1093/ofid/ofaa439.1694.
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Abstract Background In 2014, the AAP stopped recommending palivizumab for use in children with hemodynamically significant CHD (hs-CHD) aged 12 to 24 months at the RSV season start. This analysis investigates the impact of the 2014 AAP policy on the contemporary burden of RSVH and BH in children with CHD for whom palivizumab immunoprophylaxis is no longer recommended. Methods All children with CHD aged ≤ 24 months at the start of the RSV season and hospitalized for RSV or BH during the 2010-2017 RSV seasons (November-March) were studied. RSVH and BH were defined by International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) and ICD-10-CM codes. As there are no ICD codes for hs-CHD, we evaluated the effect of the guidance on higher-risk CHD as defined by ICD codes.1 Frequency and characteristics of RSVH and BH and disease severity (including intensive care unit [ICU] admission and mechincal ventilation) for these children before and after the 2014 AAP guidance using the Children’s Hospital Association’s Pediatric Health Information System® (PHIS) data set were described. SAS version 9.4 was used for statistical analysis of this data, with z-tests method used to determine statistical significance. Results RSVH significantly increased after 2014 for all higher-risk CHD children aged ≤ 24 months (3.4% [1992 RSVH CHD/59,217 RSVH] before the 2014 guidance and 4.0% [1798 RSVH CHD/45,470 RSVH] after; P< 0.0001) and for the subgroup of children aged 12 to 24 months at the start of the RSV season (0.5% before the guidance and 0.8% after; P< 0.0001). Disease severity as measured by ICU admissions in the 12 to 24 months subgroup also significantly increased after the 2014 guidance (0.2% before the guidance and 0.3% after; P< 0.0001). Mechanical ventilation usage was not statistically significantly increased after the 2014 guidance (P=0.188). A similar pattern of results was found for BH. Conclusion RSVH, BH, and associated disease severity significantly increased among higher-risk CHD children aged 12 to 24 months, within the PHIS health system, after the 3 RSV seasons following the 2014 AAP RSV immunoprophylaxis recommendations. Disclosures Jaime Fergie, MD, AstraZeneca (Speaker’s Bureau)Sobi, Inc. (Speaker’s Bureau) Tara Gonzales, MD, Sobi, Inc. (Employee) Mina Suh, MPH, International Health, EpidStrategies (Employee) Xiaohui Jiang, MS, EpidStrategies (Employee) Jon Fryzek, PhD, MPH, EpidStrategies (Employee) Adam Bloomfield, MD, FAAP, Sobi, Inc. (Employee)
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Kepha, Stella, Duncan Ochol, Florence Wakesho, Wyckliff Omondi, Sammy M. Njenga, Kariuki Njaanake, Jimmy Kihara, et al. "Precision mapping of schistosomiasis and soil-transmitted helminthiasis among school age children at the coastal region, Kenya." PLOS Neglected Tropical Diseases 17, no. 1 (January 5, 2023): e0011043. http://dx.doi.org/10.1371/journal.pntd.0011043.
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Background Accurate mapping of schistosomiasis (SCH) and soil transmitted helminths (STH) is a prerequisite for effective implementation of the control and elimination interventions. A precision mapping protocol was developed and implemented in the coastal region of Kenya by applying the current World Health Organization (WHO) mapping guide at a much lower administrative level (ward). Methods A two-stage cluster survey design was undertaken, with 5 villages in each ward selected. From within each village 50 households were randomly selected, and a single child between the ages of 8 and 14 sampled following appropriate assent. The prevalence and intensity of infection of Schistosoma mansoni and STH were determined using the Kato-Katz method (single stool, duplicate slides) and urine filtration for S. haematobium. Results Of the 27,850 school age children sampled, 6.9% were infected with at least one Schistosoma species, with S. haematobium being the most common 6.1% (95% CI: 3.1–11.9), and Tana River County having highest prevalence 19.6% (95% CI: 11.6–31.3). Prevalence of any STH infection was 5.8% (95% CI: 3.7–8.9), with Lamu County having the highest prevalence at 11.9% (95% CI: 10.0–14.1). The most prevalent STH species in the region was Trichuris trichiura at 3.1% (95% CI: 2.0–4.8). According to the WHO threshold for MDA implementation, 31 wards (in 15 sub-Counties) had a prevalence of ≥10% for SCH and thus qualify for annual MDA of all age groups from 2 years old. On the other hand, using the stricter Kenya BTS MDA threshold of ≥2%, 72 wards (in 17 sub-Counties) qualified for MDA and were targeted for treatment in 2021. Conclusions The precision mapping at the ward level demonstrated the variations of schistosomiasis prevalence and endemicity by ward even within the same sub-counties. The data collected will be utilized by the Kenyan Ministry of Health to improve targeting
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Cummins, Sharen J., and Murray Rudman. "An SPH Projection Method." Journal of Computational Physics 152, no. 2 (July 1999): 584–607. http://dx.doi.org/10.1006/jcph.1999.6246.
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Sbeity, Fatima, Sébastien Ménigot, Jamal Charara, and Jean-Marc Girault. "Contrast Improvement in Sub- and Ultraharmonic Ultrasound Contrast Imaging by Combining Several Hammerstein Models." International Journal of Biomedical Imaging 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/270523.
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Sub- and ultraharmonic (SUH) ultrasound contrast imaging is an alternative modality to the second harmonic imaging, since, in specific conditions it could produce high quality echographic images. This modality enables the contrast enhancement of echographic images by using SUH present in the contrast agent response but absent from the nonperfused tissue. For a better access to the components generated by the ultrasound contrast agents, nonlinear techniques based on Hammerstein model are preferred. As the major limitation of Hammerstein model is its capacity of modeling harmonic components only, in this work we propose two methods allowing to model SUH. These new methods use several Hammerstein models to identify contrast agent signals having SUH components and to separate these components from harmonic components. The application of the proposed methods for modeling simulated contrast agent signals shows their efficiency in modeling these signals and in separating SUH components. The achieved gain with respect to the standard Hammerstein model was 26.8 dB and 22.8 dB for the two proposed methods, respectively.
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Khoo, Teresa, Amy Spallone, Audun Lier, Yasin Abul, Anna-Marie Wellins, Fredric Weinbaum, Benjamin Luft, and Luis A. Marcos. "Lyme Disease in Hispanics in Long Island, New York: A New Health Disparity in the U.S." Open Forum Infectious Diseases 4, suppl_1 (2017): S308. http://dx.doi.org/10.1093/ofid/ofx163.715.
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Abstract Background Lyme disease (LD) is the most commonly reported vector-borne illness in the U.S. A risk factor for acquiring LD is the exposure to outdoors. In Long Island, Hispanics compromise a large share of the outdoor occupational workforce. Methods A retrospective chart review was performed in all patients with ICD-9 or ICD-10 diagnostic codes for LD between 2011–2016 in SHH and 2010–2015 in SBUH. Inclusion criteria was defined as a clinical scenario compatible with LD (erythema migrans -EM, arthritis, central nervous system (CNS) involvement, carditis, meningitis) and serological confirmation by western blot according to CDC (SBUH) or Imugen® (SHH) criteria. Results Out of 1,026 cases (766 SBUH;260 SHH) that carried a diagnosis of LD, 284 cases (22% Hispanics) met inclusion criteria and were added to final analysis (241 SBUH: 43 SHH). The mean age was 48.8 (SD:17.8) and 48.3 (SD:17.5) years-old in H and NH, respectively (p > 0.05). Most were male (H:62.2%; NH: 54.3%; P = 0.2). In the univariate analysis, headaches were more frequently present in H (42.6%) than in NH (26.6%) (P = 0.015). In the logistic regression analysis, the following symptoms were significantly different between H and NH: headaches (OR 1.17, 96% CI 1.60–6.59, 
P = 0.001) and peripheral neuropathy (OR 0.38, 95% CI: 0.15-0.96, P = 0.04). Among seasons, H were more frequently diagnosed with Lyme during spring months than NH (H: 26.3% vs. NH: 12.6%, P = 0.03) Conclusion Hispanics have a greater risk for presenting with headaches and less peripheral neuropathy than NH. Initiation of outdoor work among H may be the reason of this disproportionate presentation of LD symptoms during spring months. These findings may suggest the propensity for Hispanics to go underdiagnosed with LD, despite their high likelihood of exposure through their occupations in this region. Disclosures All authors: No reported disclosures.
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Njenga, Sammy M., Henry M. Kanyi, Cassian M. Mwatele, Dunstan A. Mukoko, Moses J. Bockarie, and Louise A. Kelly-Hope. "Integrated survey of helminthic neglected tropical diseases and comparison of two mosquito sampling methods for lymphatic filariasis molecular xenomonitoring in the River Galana area, Kilifi County, coastal Kenya." PLOS ONE 17, no. 12 (December 9, 2022): e0278655. http://dx.doi.org/10.1371/journal.pone.0278655.
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A lymphatic filariasis (LF) endemic focus along the River Galana/ Sabaki in Kilifi County, coastal Kenya, provided a platform to conduct an integrated survey for three helminthic neglected tropical diseases (NTDs), namely soil-transmitted helminthiasis (STH), schistosomiasis (SCH) and LF. Additionally, the study compared the performance of two mosquito trapping methods for LF molecular xenomonitoring (MX). Cross-sectional surveys measuring STH, SCH and LF prevalence were conducted in four villages. Mosquitoes were trapped using the CDC light trap (CDC-LT) and the Ifakara A tent trap (Ifakara-TT) methods and stored in pools which were tested for Wuchereria bancrofti DNA using the real-time polymerase chain reaction assay. A total of 907 people (436 adults; 471 children) participated in the parasitological testing. Among the STH infections, Trichuris trichiura and hookworms were most prevalent among the children and adult populations, respectively. The schistosome worm eggs detected belonged to the species Schistosoma haematobium and the prevalence of the infection was generally higher among the children compared with the adult population. The prevalence of LF infection among the adult population ranged from 1.8% to 7.6% across all 4 villages (P < 0.05). A total of 3,652 mosquitoes, including Anopheles, Culex, Mansonia, and Aedes species were collected. One mosquito pool consisting of Anopheles mosquitoes tested positive for filarial DNA out of 1,055 pools that were tested. The CDC-LT caught significantly more mosquitoes compared with the Ifakara-TT (P < 0.001). This study demonstrated that integrated epidemiological surveys using standard parasitological and entomological methods can provide useful information on co-endemic parasitic diseases which could help direct interventions and surveillance activities.
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Kikuchi, Masanori, and Masamitsu Suzuki. "Crack Analysis by SPH Method." Proceedings of The Computational Mechanics Conference 2002.15 (2002): 373–74. http://dx.doi.org/10.1299/jsmecmd.2002.15.373.
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SAKAI, Yuzuru, Tetuya Okamoto, and Akihiko Yamashita. "Structural Analysis by SPH Method." Proceedings of The Computational Mechanics Conference 2003.16 (2003): 955–56. http://dx.doi.org/10.1299/jsmecmd.2003.16.955.
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Tymchuk, Dmytro S., Iurii Sadovnichenko, Nataliya Tymchuk, Halyna Potapenko, and Inna Torianyk. "Oleic Acid Glycerides Content in the Oils of Maize Endospermic Mutants and Its Dependence on Temperature During Ripening." Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences. 75, no. 5 (October 1, 2021): 403–10. http://dx.doi.org/10.2478/prolas-2021-0059.
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Abstract Identification of sources of increased content of oleic acid glycerides (oleates) and determination of the nature of its variability are prerequisites for improving oil quality. The purpose of this study was to establish the variability of the content of oleic acid glycerides (oleates) in maize oil depending on the genotype and ripening temperature. The experiments were carried out on a series of common maize inbreds and inbred-carriers of the su1, ae, and su2 mutations, which were grown for three years. The fatty acid composition of the oil was analysed by the Peisker gas chromatographic method. Genotype–environment interactions were assessed using the Eberhard– Russell algorithm. It was found that the carriers of the su1 and su2 mutations had the highest oleate content. The oleate content of maize oil generally increased with increasing ripening temperature. Unrelated inbreds based on one mutation significantly differed in the genetically determined level of oleate and showed non-identical responses to the ripening temperature. In inbreds of the first type, the content of oleates changed significantly with temperature fluctuation, while inbreds of the second type provided a fairly stable level of the trait under these conditions.
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Vyas, Dhairya R., Sharen J. Cummins, Murray Rudman, Paul W. Cleary, Gary W. Delaney, and Devang V. Khakhar. "Collisional SPH: A method to model frictional collisions with SPH." Applied Mathematical Modelling 94 (June 2021): 13–35. http://dx.doi.org/10.1016/j.apm.2021.01.005.
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Susa, Hajime. "SPH Radiative Hydrodynamics Methods." Proceedings of the International Astronomical Union 6, S270 (May 2010): 195–202. http://dx.doi.org/10.1017/s1743921311000366.
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AbstractIn this paper, we review the radiative hydrodynamics methods based upon Smoothed Particle Hydrodynamics(SPH). There are already various implementations so far, which can be categorized into three types: moment equation solvers, Monte Carlo methods, and ray-tracing schemes. These codes have been applied to various astrophysical problems including dynamics of dense proto-stellar cores, photoionization feedback of massive stars on molecular clouds, radiative feedback in the early universe, etc. Among these different methods, we focus on the ray-tracing schemes. We also describe one particular ray-tracing code RSPH in some details.
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Vayalthrikkovil, S., R. A. Bashir, L. Espinoza, L. Irvine, and K. Mohammad. "Prevalence and Characteristics of Intracranial and Extracranial Hemorrhages in Neonates with Hypoxic Ischemic Encephalopathy (HIE)." Paediatrics & Child Health 21, Supplement_5 (June 1, 2016): e82-e82. http://dx.doi.org/10.1093/pch/21.supp5.e82.
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Abstract BACKGROUND: Intracranial hemorrhages (ICH) and extracranial hemorrhages(ECH) are not uncommon in neonates with HIE. The risk factors of hemorrhages and their association with HIE severity and other therapeutic interventions are unclear. OBJECTIVES: To examine the prevalence and risk factors associated with ICH and ECH in neonates with HIE. DESIGN/METHODS: A retrospective cohort study of neonates admitted with HIE from September 2011 to October 2015 in a level III NICU. ICH[mainly subdural(SDH), intraventricular (IVH), intraparenchymal (IPH)] and ECH [mainly subgaleal(SGH) and cephalhematoma] were diagnosed by MRI.Perinatal and neonatal characteristics were examined, including mode of delivery, outborn status, HIE staging(using modified Sarnat scoring), therapeutic hypothermia(TH), clinical/EEG seizures, hypo/hypercarbia, inotrope use, thrombocytopenia-mild, moderate, severe(platelet count 100-150, 50-100, 1.8, activated partial thromboplas-tin time(aPTT)>45 sec, fibrinogen RESULTS: Number of HIE patients,n=157; median gestation 40 weeks(IQR 38-40); outborn=104(66%);TH used=103(66%);MRI brain done=138. . Prevalence of SDH,IPH,IVH and SGH were 47,22,9,9 (34%,16%,6.5%,6.5%) respectively. There was no significant increase in hemorrhage with mode of delivery except instrumentation, seizures, hypo/ hypercarbia, severe thrombocytopenia or deranged coagulation. Instrumental delivery significantly increased the prevalence of IPH and SGH. All hemorrhages except cephalhematoma increased with severity of HIE staging, but not with MRI severity. In the logistic regression analysis, use of dopamine was associated with increased risk of IPH(OR 2.94; 95% CI 1.42, 12.08) and trended towards increased risk of IVH (OR 4.49; 95% CI 0.98, 20.6). CONCLUSION: SDH followed by IPH are the common ICH. Despite being frequent, thrombocytopenia and deranged coagulation did not increase the risk of ICH or ECH in HIE; dopamine use associated with significant increase in the risk of IPH.