Academic literature on the topic 'Subject headings Use studies'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Subject headings Use studies.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Journal articles on the topic "Subject headings Use studies"
1
Clements, Lucy, and Chern Li Liew. "Talking about tags." Electronic Library 34, no. 2 (April 4, 2016): 289–301. http://dx.doi.org/10.1108/el-12-2014-0216.
Full textAbstract:
Purpose – While examining subject headings and tags is a popular research topic, most studies focus on comparing user-assigned tags and professional subject heading. Studies that compare Library of Congress Subject Headings to user-assigned tags, for instance, dominate the literature. However, little research has involved an examination on how and to what extent these features are actually used by library staff. This study adds to the body of knowledge. This study aims to focus on how librarians perceive and use tags. By focusing on people’s perceptions rather than simply comparing social tags and formal subject headings, new insights can be collected. Design/methodology/approach – This research collects data through semi-structured interviews conducted with 12 library staff from various roles and locations throughout Auckland Libraries. Findings – The research findings show that while social tags have been adopted and used in their work by the majority of library staff interviewed, there remains resistance to using them. Some library staff preferred the traditional hierarchical subject headings found in the traditional catalogue. A general lack of awareness about tag functions and features is also evident among the staff interviewed. Originality/value – The research focus is unique because it examines this phenomenon in a public library setting rather than in academic libraries, an area that is rarely examined in the literature.
2
Isbister, Christian. "Indians in the Database." Pathfinder: A Canadian Journal for Information Science Students and Early Career Professionals 2, no. 2 (May 4, 2021): 2–17. http://dx.doi.org/10.29173/pathfinder38.
Full textAbstract:
The goal of this exploratory research study is to better understand how students in the Faculty of Native Studies at the University of Alberta relate to terminology for Indigenous peoples in Canada, namely Indian, in controlled vocabulary subject headings. The language used in controlled vocabularies to describe resources about Indigenous peoples does not always reflect terms Indigenous peoples use to describe themselves, leading to a disconnect between users and subject headings. Although this issue is beginning to enter academic discourse alongside reconciliation efforts, to date no research study has examined how students react to this issue. In this study interviews were conducted with five students from the Faculty of Native Studies to better understand how they relate to terminology. Students reported feeling uncomfortable at being forced to use language they saw as racist or insensitive. Future research should be conducted to better understand student relationships with subject headings, particularly at different institutions
3
Still, Julie, and Zara Wilkinson. "The use of librarians as occupational study populations in social science research." Library Review 63, no. 1/2 (May 2, 2014): 2–14. http://dx.doi.org/10.1108/lr-07-2013-0092.
Full textAbstract:
Purpose – The purpose of this paper is to address the use of librarians as a study population in social science research outside of the field of library and information science. Additionally, it aims to make general claims about how frequently librarians have been studied compared to other occupations, as well as to identify and describe existing research that has used librarians as a study population. Design/methodology/approach – The described study had two parts. Two social science databases were searched using the subject headings “librarians” and eight additional occupations, and the results for all nine occupations were analyzed. The peer-reviewed results for “librarians” were then coded by content. The articles that used librarians as a study population were identified, reviewed and described. Findings – Although librarians, as an occupational group, possess many characteristics that should make them an ideal choice for social science research, they seem to be studied less frequently than other occupations. Research limitations/implications – Other occupational groups, such as mathematicians, were also studied infrequently. Further research might consider, more broadly, why some occupations are studied more frequently than others. Future studies might also compare librarianship to other female-dominated professions, such as nursing and education. Additionally, the subject heading “librarians” was applied to articles that studied non-professional library employees, making it difficult to isolate only articles with a focus on degreed librarians. Originality/value – Few other studies have examined social science research in which librarians are used as the study population. By focusing on how librarians are studied and written about in other fields, this paper will add to the body of literature on the professional image of librarians.
4
SAMANTA, KALYAN SUNDAR. "User Generated Social Tags Versus Librarian Generated Subject Headings, A Comparative Study in the Domain of History." DESIDOC Journal of Library & Information Technology 40, no. 03 (May 26, 2020): 176–84. http://dx.doi.org/10.14429/djlit.40.03.15413.
Full textAbstract:
Social tagging allows users to assign any free-form keywords as tags to any digital resources through a decentralised way. Many information scientists find that there are similarities through their studies between usergenerated social tags and the librarian-generated subject headings for the libraries. The present study was conducted to identify the similarity and dissimilarity between user-generated social tags and librarian-generated subject terms of 1000 books in the domain of History. The study also conducted to identify whether social tags can replace controlled vocabularies. The study finds that only a small portion of terms overlaps with each other (3.54 % of social tags & 56.07 % of SLSH terms) and Spearman’s rank correlation proves that there is a good association between overlapping terms. Jaccard similarity coefficient highlights that users and the librarian use different terminologies (as J = 0.13, 0.12 & 0.11). Individual title wise comparison also defines that 90 per cent (88.4 %) of all book titles where users and the librarian use at least one common term. Users use the least subject & non-subject terms but use some personal tags for personal benefit whereas the librarian use only subject & non-subject terms. Matching with each book title clarifies that for describing resources users mostly use title based keywords (696) whereas the librarian use very little title based keywords (113). The study clearly defines that social tags can enhance the experience of library users. If it can be exploited properly it can complement to controlled vocabularies but can not replace the controlled vocabularies used for libraries a long time. Overall the study explicitly identifies the viability regarding the adoption of social tags into the library databases where the resources in the field of history will be accessed.
5
Camargo, Edina, Rogerio Fermino, and Rodrigo Reis. "Barriers and facilitators to bicycle use in adults: a systematic review." Revista Brasileira de Atividade Física & Saúde 20, no. 2 (September 4, 2015): 103. http://dx.doi.org/10.12820/rbafs.v.20n2p103.
Full textAbstract:
<p>The aim of this systematic review was to summarize the evidence on the barriers and facilitators to the use of bicycles in adults. Search terms were defined using Health Sciences Descriptors (DeCS) and Medical Subject Headings (MeSH) and evidence was searched in the following databases: Lilacs, SciELO, PubMed, Web of Science and Science Direct. A total of seven studies met the inclusion criteria and showed that the main barriers and facilitators to the use of bicycles are related to the physical, social and natural environment characteristics and individual characteristics (cognitive, psychological and emotional aspects). Interventions in the area of public health should consider these features to increase the use of bicycles in adults.</p>
6
Amani, Armaghan, Caitlin M. Fellers, Antoinette Eyebe, Alyssa Hall, and Meredith L. Howard. "Safety and Efficacy of Apixaban Use in Peritoneal Dialysis: A Review of the Literature." Journal of Pharmacy Technology 37, no. 3 (January 20, 2021): 147–51. http://dx.doi.org/10.1177/8755122520988728.
Full textAbstract:
Objective: To review the safety and efficacy of apixaban for the treatment of nonvalvular atrial fibrillation or venous thromboembolism in patients receiving peritoneal dialysis (PD). Data Sources: A PubMed and MEDLINE search was conducted through December 2020 using the following keywords and Medical Subject Headings (MeSH) terms alone or in various combinations: apixaban, peritoneal dialysis, continuous ambulatory peritoneal dialysis, end-stage renal disease, and hemodialysis. Study Selection and Data Extraction: English-language studies evaluating clinical outcomes pertaining to the use of apixaban in end stage renal disease (ESRD), which included patients receiving peritoneal dialysis were eligible for inclusion. Data Synthesis: Four studies were identified that met inclusion for this review, all retrospective in nature. These studies compared the safety and efficacy of apixaban with standard therapy in ESRD included patients on dialysis, with a very limited number of subjects receiving PD. In these studies, apixaban was shown to be potentially safer and more effective than warfarin. Outcomes did not differentiate between patients receiving PD or not. Conclusions: Use of apixaban in patients receiving PD may be safe and effective based on data from limited patients. Pharmacokinetics and pharmacodynamics of apixaban in the PD setting is an important question that clinicians should consider with use of this medication in the ESRD population. More studies focusing on the PD population are needed to better assess the use of apixaban in this understudied population.
7
Libraries, North Carolina. "Library and Information Science Research 1999-2001: A bibliography of Master's Papers from the University of North Carolina School of Information and Library Science." North Carolina Libraries 60, no. 1 (January 21, 2009): 26. http://dx.doi.org/10.3776/ncl.v60i1.239.
Full textAbstract:
Agnew, Laura. “Characteristics and Benefits of Online Support Groups.” 135 pages. July 2001. Headings: Information services – Special subjects – Disease; Virtual communities – Medical; Information needs – Medicine; Information eds – Self-help; Surveys – Information needs; Use studies – Internet.
8
Dovbnya, Elena V. "Problems of Subject Retrieval in the Electronic Catalogue of Scientific Library: Review of Studies." Bibliotekovedenie [Russian Journal of Library Science] 69, no. 4 (November 6, 2020): 367–74. http://dx.doi.org/10.25281/0869-608x-2020-69-4-367-374.
Full textAbstract:
Scientific libraries use different approaches and tools for subject retrieval. Issues related to electronic subject retrieval are widely discussed in the library community. The purpose of this review is to analyse publications of recent years on the aspects and problems related to subject retrieval in electronic catalogue (EC). For its preparation, the author used publications (and references to them) taken from the national bibliographic database — the Russian Science Citation Index (RSCI); the time coverage is 2003—2019. Particular attention in the studies is focused on the need to combine different information retrieval languages (IRL), thesauruses, subject headings and keywords to ensure effective and multi-aspect search. Since the domestic libraries have accumulated a lot of experience in indexing and retrieval through hierarchical classifications (UDC and LBC), it is necessary to use this at the full extent in the electronic subject retrieval. The authors of the recent studies on subject retrieval consider being the most effective the functioning of classification systems as part of the complex of linguistic tools of electronic catalogue. In the electronic environment, it becomes possible to use classification indexes as a set of characters that maximally reflect the content of the document, what involves the use of all fragments of the index as independent retrieval elements. However, the lexical composition of the classification information retrieval languages needs to be modified for effective use in the electronic catalogue. The main directions here can be as follows: unification of the structure and vocabulary of classification schedules, optimization of the structure of classification systems (using facetization principles), as well as formalization of the use of grammar tools, (it is necessary to ensure the unambiguity of their interpretation in the electronic catalogue). The review presents and analyses the areas where the subject retrieval has been developed in the electronic environment for over the past 16 years. For example, there has been developed and is being implemented the superstructure over Universal Decimal Classification (Library for Natural Sciences of the Russian Academy of Sciences), which allows users of the library to remotely conduct full-fledged subject retrieval. The paper also presents the new developments by the Russian State Library on subject retrieval, in particular, the project “Presentation of classification metadata of electronic libraries using linked data technology”. The author concludes that it is necessary to form a common space of related open data of various libraries.
9
Vijayan, Vishnu, Anirban Mallick, and Jahnavi Dande. "Headgear in prevention of sports related concussion- A literature review across various sports." IP Indian Journal of Neurosciences 7, no. 3 (September 15, 2021): 186–91. http://dx.doi.org/10.18231/j.ijn.2021.033.
Full textAbstract:
Sports related concussion (SRC) remains a challenge for sports physicians to identify because of varied presentation and lack of diagnostic tool. Keeping in mind its long term effect various sports bodies introduced different preventive strategies to reduce incidence of SRC. Commercial headgear is currently being used by players of all ages and skill levels in certain sports to protect themselves from heading and direct impact, even though the protective effect on concussion has not been conclusively demonstrated and limited research has been done. Electronic databases and grey literatures were used to search the evidence using Medical Subject Headings sports headgear, concussion, helmet, cricket, soccer, American Football, boxing for the available research studies from 1990 up to April 2020. The wide variety of prospective surveillance as well as lab studies made the case even more confusing as the simulation model may not actually replicate the on field scenario. Moreover the type and component of the headgear need to be subjected based on sports specific demand. Hence this literature review is aimed at available evidences in different sports to find any consensus between use of headgear and prevention of SRC.
10
Diamond, James A. "The Use of Midrash in Maimonides' Guide of the Perplexed: Decoding the Duality of the Text." AJS Review 21, no. 1 (April 1996): 39–60. http://dx.doi.org/10.1017/s0364009400007613.
Full textAbstract:
In the introduction to his philosophical magnum opus, the Guide of the Perplexed, Maimonides provides us with a rationale for the composition of this work as well as instructions for the targeted reader on how to decipher its elusive and enigmatic style. Such devices as contradiction, diffuse and seemingly discordant treatment of subject matter, and deliberate ruses are employed to accommodate both halakhic legal constraints on the overt teaching of physics and metaphysics and the wide intellectual disparity of his potential readers. The sensitive nature of the topics to be explored demands an unorthodox pedagogy that both illuminates and conceals, allowing entrance to the qualified few while excluding those who cannot cope with the intellectual rigors involved. Rabbinic stricture prohibits revealing anything more of the Account of the Chariot (metaphysics) than chapter headings, and therefore Maimonides cautions, “my purpose is that the truths be glimpsed and then again be concealed so as not to oppose that divine purpose which has concealed from the vulgar among the people those truths requisite for His apprehension.”
Dissertations / Theses on the topic "Subject headings Use studies"
1
Carman, Nicholas. "LibraryThing tags and Library of Congress Subject Headings a comparison of science fiction and fantasy works : submitted to the School of Information Management, Victoria University of Wellington in partial fulfilment of the requirements for the degree of Master of Library and Information Studies /." ResearchArchive@Victoria e-Thesis, 2009. http://hdl.handle.net/10063/1272.
Full text
2
Gibbs, Richard Stephen. "The use of headings and text organization as aids to recall of expository prose in grade 5 through 10 with an emphasis on grades 9 and 10." Thesis, University of British Columbia, 1985. http://hdl.handle.net/2429/25410.
Full textAbstract:
This study investigated the effects of headings and text organization on grade 5 through 10 students' written recall of expository prose passages written in a classification/description mode. Emphasis was placed on the results from students in grades 9 and 10. This study was a component of a three part study. The other two parallel studies emphasized grades 5 and 6 (Stables, 1985) and 7 and 8 (King, 1985). Each subject read and recalled two passages: one written at his or her grade level and one written at a low readability level. Performance on the written recalls from passages with headings and without headings was examined on the basis of the number of superordinate and subordinate ideas recalled, the superordinate and subordinate organization, and the format. Developmental trends were investigated by including the data from the two parallel studies (Stables, 1985; King, 1985).
There was some evidence that headings had a significant effect on the number of superordinate ideas recalled from a passage of low readability. Some significant differences indicated negative effects by headings. The majority of differences, however, were not significant. Developmental trends in grades 5 through 10 were noted in the number of ideas recalled on a low readability passage and the format used on the written recalls. Implications for instruction and suggestions for further research are discussed.Education, Faculty of
Language and Literacy Education (LLED), Department of
Graduate
3
Avraam, Elsa. "Knowledge Organisation and Contemporary Art : Cataloguing Practices in two Libraries in Sweden, Umeå universitetsbibliotek and Konstbiblioteket." Thesis, Uppsala universitet, Institutionen för ABM, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-334088.
Full textAbstract:
This master thesis examines the cataloguing practices of two art libraries in Sweden in relation to contemporary art. The aim of this study is to show how classification systems and other forms of controlled vocabulary correspond to contemporary art and reveal the factors that influence the everyday practice of cataloguing. The qualitative methods of semi-structured interviews and an analysis of bibliographic records have been used for the purposes of this study. The study is based on domain analysis as conceived by Hjørland and Albrechtsen and some concepts and principles of Knowledge Organisation in the field of Library and Information Science. A total of three interviews of cataloguers has proved that perceptions concerning classification and subject indexing differ among cataloguers and cataloguing practices depend on local policies concerning acquisition, shelving and user perspectives, but also each library’s resources and the institutional context (academic vs museum). Through the analysis of eleven bibliographic records, no consistent pattern has been detected, in relation to indexing and classification. The libraries do not use special systems for subject analysis. The classifications provided by universal systems have been considered insufficient to express all the concepts found in documents. The use of subject headings is, therefore, important and complements the process of subject analysis. The classification systems and subject headings lists analysed include the Dewey Decimal Classification (DDC), the Swedish Sveriges Allmänna Biblioteksförenings Klassifikationssystem (SAB) and the Svenska ämnesord (SAO). This is a two-year master’s thesis in Archive, Library and Museum studies.Denna masteruppsats handlar om katalogiseringspraktiker på två konstbibliotek, nämligen Umeå universitetsbibliotek och Konstbiblioteket, i relation till samtida konst. Syftet med denna studie är att visa hur samtida konst återspeglas i klassifikationssystem och andra former av kontrollerad vokabulär och ta reda på vilka faktorer påverkar katalogiseringsarbete. Metoden som har använts i studien består av halvstrukturerade intervjuer med katalogisatörer och en analys av bibliografiska poster. Studien baseras på domänanalys som har utarbetats av Hjørland och Albrechtsen samt vissa begrepp och principer från Kunskapsorganisation inom ramen för Biblioteks- och Informationsvetenskap. Analysen av tre intervjuer visade på att uppfattningar om klassifikation och ämnesordsindexering skiljer sig åt bland katalogisatörer och att katalogiseringspraktiker beror på varje biblioteks riktlinjer med avseende på förvärv, hylluppställning, användarperspektiv, bibliotekets resurser samt institutionell kontext (akademisk vs museal). Elva bibliografiska poster har analyserats och genom analysen har inga mönster i relation till ämnesordsindexering och klassificering identifierats. De undersökta bibliotek använder inte något specialsystem för klassifikation eller ämnesordsindexering. Klassifikationskoder från universella system ansågs otillräckliga för att uttrycka alla begrepp i dokumenten. Ämnesordsindexering är därför viktig och anses vara mer effektiv för ämnesanalys. Klassifikationsssystem och ämnesordlistor som har analyserats är Dewey Decimal Klassifikation (DDK), Sveriges Allmänna Biblioteksförenings Klassifikationssystem (SAB) och Svenska ämnesord (SAO). Detta är en tvåårig masteruppsats i Arkiv-, Bibliotek- och Museumstudier.
4
Hed, Anna. "Kategorier i kontrollerade ämnesordlistor : En kritik ur ett pragmatiskt perspektiv." Thesis, Uppsala universitet, Institutionen för ABM, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-413712.
Full textAbstract:
Subject description is a linguistic practice, and therefore all controlled vocabularies are built upon theories of language. However, the underlying theories are rarely discussed in greater length. The purpose of this thesis is to investigate what epistemological foundations controlled vocabularies are built upon and what consequences that has for their internal structure. The main object of interest is the category. From a rationalistic point of view categories are universal and well defined. In a pragmatic point of view categories are contextual with fluid boundaries. A pragmatic point of view has been shown by Wittgenstein and Rosch to more accurately describe how language works, therefore the standpoint of this thesis is that a controlled vocabulary that takes a pragmatic approach will be a better tool for indexing and searching. The study is done in three parts. First the theoretical literature on knowledge organisation is investigated. The findings are that there is a divide among writers who take a rationalistic and pragmatic approach. Then, guidelines and principles from IFLA, LCSH, Svenska ämnesord and MeSH are examined. In all cases the rationalist view is favored but the quirks of language are handled in different ways. In IFLA's FRSAD, the writers claim to take no theoretical stance but in reality they take a rationalistic perspective. LCSH blame the inconsistencies in the system on the many people that have worked on it over a long period of time. SAO is built with LCSH as a role model and therefore have the same problems, although they have gone towards a more pragmatic approach. MeSH, however, acknowledges that language is more complicated, and the controlled vocabulary is built on a more pragmatic foundation. Lastly, examples from the controlled vocabularies are discussed. The finding is that, in practice, controlled vocabularies work in accordance with a pragmatic perspective. This is a two years master’s thesis in Library and Information Science.
5
Olsson, Carl. "The Poet as Hero : A Study of the Clash Between the Hero and the First World War in British Trench Poetry, and Its Use in the Swedish School System Within the Subject of English." Thesis, Linnéuniversitetet, Institutionen för språk (SPR), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-76592.
Full textAbstract:
This thesis studies the clash between the hero and the First World War in the works of Rupert Brooke, Siegfried Sassoon and Wilfred Owen. It explores the impact on their poetry and attitude towards the concept of the hero as it applied to them as people and poets. The study shows that over prolonged contact with the horrors of the First World War, it is evident in both literary sources and their poetry that both Sassoon and Owen changed their attitudes negatively towards both the idea of heroes and heroism, as well as the War as a just and glorious cause. However, the myth of the hero was still a core belief of their society, and in order to not be branded cowards and discarded along with their warnings, they had to become heroes in the eyes of their society, to openly attack the concept and the war it fueled. This thesis then studies how and why First World War poetry and literature should be utilized within the subject of English in the Swedish School System, as a means to provide a multicultural and critical education.
6
Dib, Ricardo Anuar. "Avaliação de sintomas e lesões esôfago-gastroduodenais secundários ao uso de antiinflamatórios." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/5/5168/tde-08112013-110643/.
Full textAbstract:
Introdução: Os antiinflamatórios não esteróides (AINEs), incluindo a aspirina, são drogas largamente utilizadas para tratamento das doenças inflamatórias e da dor, e que podem causar efeitos colaterais sérios, causando considerável morbidade e mortalidade, relacionadas á doença ulcerosa, duodenal e gástrica, particularmente ao sangramento gastrointestinal. O risco relativo global de complicações gastroduodenais é de três a dez vezes, maior nos usuários de AINEs, quando comparado com indivíduos sadios. Cerca de 25% dos usuários crônicos dos antiinflamatórios não esteroides (AINEs) deverão desenvolver doença ulcerosa, e de 2 a 4% deverão apresentar sangramento ou perfuração. Mais de 17.000.000 de norte americanos utilizam vários tipos de drogas antiinflamatórios não esteróides (AINEs) diariamente e que provocam mais de 100.000 hospitalizações e cerca de 7000 a 10.000 mortes por ano nos Estados Unidos da América do Norte, fazendo desta família de drogas uma das mais comumente usadas em todo planeta. Cerca de 50% das lesões observadas em endoscopias de controle, ocorrem sem que o paciente tenha qualquer tipo de sintoma. Acredita-se que houve recrudescimento da prevalência de lesões digestivas pela substituição dos antiinflamatórios COX-2 pelos antiinflamatórios tradicionais, principalmente pela ausência de cuidados na prevenção deste tipo de ocorrência, em populações consideradas de risco. Objetivos: a) avaliar a prevalência de lesões e complicações digestivas secundárias ao uso de AINEs; b) qual é o perfil clínico deste paciente atendido em razão de queixas digestivas e a relação destas com os achados endoscópicos. Materiais e métodos: estudo aberto, prospectivo, multicêntrico avaliando consecutivamente 1.231 pacientes submetidos a exame de endoscopia digestiva alta em virtude de queixas digestivas, única ou associadas, como: 1) pirose; 2) dor epigástrica; 3) dor abdominal; 4) náusea; 5) vômito. Antes da realização do exame de endoscopia digestiva alta, os pacientes respondiam a questionário cujo objetivo era avaliar o início e o tipo de queixa clínica, o uso de medicamentos e possíveis complicações associadas como sangramento digestivo. Os critérios de inclusão foram: pacientes de ambos os sexos com idade mínima de 18 anos e que tivessem sintomas prévios iniciados, no máximo, há 14 dias antes da realização do exame de endoscopia digestiva alta. Os critérios de exclusão foram os de pacientes que se recusaram a participar do estudo e/ou de assinar o Termo de Consentimento Livre e Esclarecido, os incapazes de responder ao questionário, os com idade inferior aos 18 anos, os pacientes que já haviam realizado cirurgia gástrica e pacientes portadores de insuficiência renal ou hepática. Resultados: Foram avaliados 1.213 pacientes de 18 a 82 anos sendo que 65% destes eram do sexo feminino, 13,1% eram fumantes e 15,6% referiam ingestão de bebidas alcoólicas. A utilização de AINEs foi mais frequente no sexo feminino, porém número de complicações foi maior nos pacientes do sexo masculino (sangramentos foi duas vezes maior; p=0,045 e a ocorrência de úlcera quase 1,5 vezes maior; p=0,041). Os principais sinais e sintomas relatados foram epigastralgia e pirose (67% e 62%, respectivamente). Os 1.213 pacientes foram alocados em dois grupos: Grupo I - AINE composto por 228 (18,8%) e o Grupo II - Não AINEs (NAINEs) por 985 (81,2%) pacientes.. O exame de endoscopia digestiva alta foi normal em 3,9% dos pacientes do grupo I e em 10,7% dos do grupo II (p< 0,001). A probabilidade de um paciente que não utiliza AINE ter endoscopia digestiva alta normal é 2,5 vezes maior quando comparado aos que utilizaram AINEs (p=0,001). As presenças de lesões erosivas ou ulceradas no estômago e duodeno também foram mais frequentes nos pacientes do Grupo I quando comparado aos do Grupo II. Observa-se que é maior a incidência de lesões, tanto erosivas quanto ulceradas no estômago quando comparadas ao duodeno (erosões: 49,12% vs 13,60 respectivamente, p=0,001; úlceras: 14,04% vs 11,84% respectivamente, p= 0,05). O risco de hemorragia digestiva, 12 vezes maior (6,14% vs 0,51%) nos pacientes que fizeram uso de AINEs sendo o estômago o sítio de maior prevalência de sangramento. Não se observou diferença estatística quando analisada a presença de esofagite erosiva nos dois grupos. Conclusões: Evidenciamos frequência maior de úlcera gástrica, úlcera duodenal e sangramento digestivo nos pacientes que utilizaram AINEs. Não foram encontradas relações entre os achados endoscópicos e os sintomas dispépticos. Não observamos influência dos AINEs no aparecimento de esofagite erosivaIntroduction: The non steroidal anti-inflammatory drugs (NSAID), including aspirin, are drugs widely used in the treatment of inflammatory diseases and pain. This use may cause serious side-effects, leading to considerable morbidity and mortality related to ulcer, duodenal and gastric disease, especially gastrointestinal bleeding. The overall relative risk of gastroduodenal complications is three to ten times higher in users of NSAID, compared to healthy individuals. Around 25% of the chronic users of non steroidal anti-inflammatory drugs (NSAID) will develop ulcer disease, and 2 to 4% will present bleeding or perforation. More than 17,000,000 North Americans use several kinds of non steroidal anti-inflammatory drugs (NSAID) on a daily basis. This causes more than 100,000 hospitalizations and from 7,000 to 10,000 deaths every year in the USA, which makes this drug one of the most commonly used on the planet. About 50% of the lesions observed in endoscopies occur without any kind of symptom. It is believed that there was an increase in the prevalence of digestive lesions due to the replacement of COX-2 anti-inflammatory drugs with traditional anti-inflammatory drugs, especially because of the lack of preventive care of this kind of occurrence in at-risk populations. Goals: a) Evaluate the prevalence of lesions and digestive complications, secondary to the use of NSAID; b) Evaluate the clinical profile of the patient seen for digestive complaints and the relation of these complaints with the endoscopic findings. Materials and Methods: Prospective, multi-centric, open study, evaluating consecutively 1,231 patients who underwent upper gastrointestinal endoscopy exam due to digestive complaints in isolation or associated, such as: 1) pyrosis; 2) epigastric pain; 3) abdominal pain; 4) nausea; 5) vomiting. Before performing the exam of upper gastrointestinal endoscopy, patients answered a questionnaire whose goal was to evaluate the onset and kind of clinical complaint, the use of medication and possible complications associated to digestive bleeding. The inclusion criteria were: Patients of both sexes with the minimum age of 18 and whose symptoms had begun up to 14 days before undergoing the upper gastrointestinal endoscopy. Exclusion criteria: patients who refused to participate in the study and/ or who refused to sign the Informed Consent Term, the ones who were unable to respond to the questionnaire, the ones who were under 18 years old, patients who had undergone a previous gastric surgery and patients with kidney or hepatic failure. Results: 1,213 patients with ages ranging from 18-82 were evaluated, 65% of which were female and 13,1% were smokers, 15,6% mentioned they ingested alcoholic beverages. The use of NSAID was more frequent among females. However, the number of complications was higher among males (bleeding occurred twice as much; p=0,045 and the occurrence of ulcer was almost 1,5 times higher; p=0,041). The main signs and symptoms reported were epigastralgia and pyrosis (67% and 62%). The 1,213 patients were divided into two groups: Group I- NSAID, made up by 228 (18,8%) and Group II- Non NSAID, made up by 985 patients (81,2%). The upper gastrointestinal endoscopy was normal in 3,9% of the patients in Group I and in 10,7% of the patients in Group II (p<0,001). A patient who does not use NSAID will be 2,5 times more likely to have normal upper gastrointestinal endoscopy than the one who used NSAID (p=0,001). The presence of erosive or ulcer lesions in the stomach and duodenum was more frequent in Group I patients when compared to those of Group II. It is observed that the incidence of lesions in the stomach, both erosive and ulcer is higher when compared to the duodenum (erosions: 49,12% vs. 13,60, p=0,001; ulcers: 14,04% vs. 11,84, p= 0,05). The risk of digestive bleeding is 12 times higher (6,14% vs. 0,51%) in patients who used NSAID, and the stomach is the site with higher prevalence of bleeding. No statistic difference was observed when the presence of erosive esophagitis in both groups was analyzed. Conclusions: We observed that the frequency of gastric ulcer, duodenal ulcer and digestive bleeding was higher in patients who used NSAID. Relations between the endoscopic findings and the dyspeptic symptoms were not found. The influence of NSAIDs on the appearance of erosive esophagitis was not observed
7
Wood, Susan Elaine. "The subject representation of core works in women's studies a critical analysis of the Library of Congress Subject Headings /." 2010. http://trace.tennessee.edu/utk_gradthes/675.
Full text
8
Wood, Susan E. "The Subject Representation of Core Works in Women's Studies: A Critical Analysis of the Library of Congress Subject Headings." 2010. http://trace.tennessee.edu/utk_gradthes/675.
Full textAbstract:
The system of Library of Congress Subject Headings (LCSH) has been the subject of feminist, critical examinations since the 1970s. Subject headings pertaining both to feminist literature and to women in general have been analyzed to determine how LCSH represents these topics. In this study, I contribute to this body of scholarship by analyzing and reporting on the nature of the LCSH subject representation of 52 core works published from 1986-1998 in the areas of feminist theory and women’s movements. These monographs were selected from the 3rd edition of Women’s Studies: A Recommended Bibliography (Krikos & Ingold, 2004). The analysis of works of/on feminist theory and on women’s movements is preceded by a pilot study of 24 core works on the topics of Communications, Film, Television, Media, and Journalism. I utilize the abstracts of these works in Krikos & Ingold (2004), as well as the works themselves, to establish the nature of each monograph’s perspective and scope. To this information I compare the LC subject headings employed in the bibliographic records representing these works in the Library of Congress Online Catalog in order to assess the headings’ usefulness as surrogate representations of these monographs in terms of accuracy, relevance, specificity, and currency. I present my findings as sets of problems and solutions illustrated with specific examples. Overall, LCSH is not able to represent adequately the 24 works in the pilot study sample or the 52 core works in the main study based on its current application. I conclude with a proposed set of subject headings as suggested by the abstracts of these works.
9
Oliphant, Woody. "How Worldly is the World Digital Library? : Postcolonial Critical Discourse Analysis of the Library of Congress Subject Headings." Thesis, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-23181.
Full textAbstract:
Based on previous researchers’ criticism of Euro-American bias inherent to universal analogue and digital knowledge organisation systems, this combined qualitative and quantitative postcolonial critical discourse analysis investigates the constructed meanings behind the Library of Congress Subject Headings (LCSH) controlled vocabulary hosted by the Word Digital Library’s (WDL) metadata scheme. This is done with a sample of metadata pertaining to their African cultural heritage collection. The study aims to see if the restricted controlled vocabulary exclude and marginalise situated African knowledge thereby conflicting with their ideological imperative of promoting international understanding. The use of postcolonial theory and discourse analysis theory as both the analytical theoretical framework and methodological approach, reveal that Westerncentric terms from colonial discourse dominate but do not constitute the entirety of the discourses represented by the subject headings. Relying on the assumption that the cataloguers select subject headings based on the rule of literary warrant, the reason for this preference imply an unbalanced collection rather than a biased knowledge organisation system. Therefore, the study suggests the creation of positive rhetorical spaces (Olson, 2002) by adding preferred terms that stem from marginalised situated knowledge systems that too are represented by the existing resources. This will allow for several discourses to co-exist achieving thereby a better fit with the culturally inclusionary aims of the WDL not dependent on the limits of their collection. Also acknowledged is metadata’s pragmatic rationale in support of standardisation for enhanced search and discoverability, but questioned is the sustainability of this principle if the goal is to promote equitable understanding and representation to a wide and international user group. Ultimately, recognising the bias within knowledge organisation systems will serve inclusivity more, rather than traditional claims of universality which conceal exclusion.
10
Sawyers, Reggie Eric. "Comparison of transverse and sagittal otolith sectioning for aging wild rainbow trout from East Tennessee streams." 2006. http://etd.utk.edu/2006/SawyersReggieEric.pdf.
Full textBooks on the topic "Subject headings Use studies"
1
Lester, Marilyn A. Coincidence of user vocabulary and Library of Congress subject headings: Experiments to improve subject access in academic library online catalogs. Ann Arbor, Mich: UMI Dissertation Services, 2002.
Find full text
2
Otchere, Freda E. African studies thesaurus: Subject headings for library users. Westport, Conn: Greenwood Press, 1992.
Find full text
3
Lancaster, F. Wilfrid. Thesaurus construction and use: A condensed course. Paris: United Nations Educational, Scientific, and Cultural Organization, 1985.
Find full text
4
Lancaster, F. Wilfrid. Thesaurus construction and use: A condensed course. Paris: General Information Programme and Unisist, Unesco, 1985.
Find full text
5
Galron, Yosef. Library of Congress subject headings in Jewish studies. 5th ed. Bexley, Ohio: Association of Jewish Libraries, 1996.
Find full text
6
Galron, Yosef. Library of Congress subject headings in Jewish studies. 3rd ed. Bexley, Ohio: Association of Jewish Libraries, 1992.
Find full text
7
Galron, Yosef. Library of Congress subject headings in Jewish studies. 7th ed. New York: Association of Jewish Libraries, 2000.
Find full text
8
National Information Standards Organization (U.S.). Proposed American national standard guidelines for thesaurus construction, structure and use. Gaithersburg, MD: National Institute of Standards and Technology, 1990.
Find full text
9
David, Bawden, Gilchrist Alan 1932-, and Aslib, eds. Thesaurus construction and use: A practical manual. 4th ed. London: Aslib IMI, 2000.
Find full text
10
Jean, Aitchison. Thesaurus construction and use: A practical manual. 4th ed. London: Aslib, 2000.
Find full textBook chapters on the topic "Subject headings Use studies"
1
Kaltenböck, Gunther. "Chapter 1. On the use of there -clefts with zero subject relativizer." In Studies in Language Companion Series, 17–43. Amsterdam: John Benjamins Publishing Company, 2023. http://dx.doi.org/10.1075/slcs.230.01kal.
Full text
2
Mukhina, Mariia V., Olga V. Katkova, Sergey E. Revunov, Zhanna V. Smirnova, and Tatyana N. Tsapina. "The Use of Digital Technologies in the Implementation of the Meta-Subject Approach as a Trend in the Development of the International Educational Environment." In Studies in Big Data, 29–37. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-04903-3_4.
Full text
3
Németh T., Enikő. "Chapter 5. Hungarian verbs of natural phenomena with explicit and implicit subject arguments: Their use and occurrence in the light of data." In Studies in Language Companion Series, 103–32. Amsterdam: John Benjamins Publishing Company, 2014. http://dx.doi.org/10.1075/slcs.153.05nem.
Full text
4
Uhl, André, and Edgar Göll. "The Use of Internal Crowdsourcing for Qualification and Competence Development in Organizations." In Contributions to Management Science, 169–99. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-52881-2_10.
Full textAbstract:
AbstractThis article deals with the question of how internal crowdsourcing can be used as a tool to support employee qualification measures and help develop their competencies in organizations. The first chapter examines the current state of the competence research. A paradigm shift from ‘qualification and professional development’ towards ‘competencies’ and the implications for the concept are described. Chapter “An Introduction to Internal Crowdsourcing” deals with the analyses and work on the subject of competence acquisition and development, including considering the results of two interview series and two workshops. In chapter “Managing the Crowd: A Literature Review of Empirical Studies on Internal Crowdsourcing”, the authors present a combined and practical approach to support competence development through internal crowdsourcing in organizations. Finally, the last chapter sums up main results and perspectives for competence development through a combination of virtual and face-to-face working processes.
5
Han, Jinghe. "Pragmatic Transfer: Reflecting on the Use of EMI Lecturers’ Pragmatic Markers." In SpringerBriefs in Education, 83–97. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-19904-2_6.
Full textAbstract:
AbstractAcknowledging the critical nature of EMI lecturers as bi- or multilinguals, this Chapter continues the investigation into cross-linguistic influence now turning attention to its pragmatic features. It focuses on the Chinese lecturers’ metalinguistic skills, particularly the L1 (Chinese) to L2 (English) transfer in their use of pragmatic markers (PMs). The investigation is informed by current studies arguing that highly proficient L2 language users do not necessarily make the most effective teachers, and the capacity to employ pragmatic strategies is essential to engage students’ learning; and that from amongst all the competencies in which lecturers should be proficient, one of the most essential is pragmatic competence. This Chapter provides an analysis of the participating EMI lecturers’ verbal characteristics of the PMs they implemented in their teaching. Whilst acknowledging individual differences, the trend of PM use and the degree of pragmatic transfer revealed in this group’s EMI teaching can be explained in terms of their pedagogical ideologies and subsequent practice, culturally influenced teacher-student relationships, the EMI discipline and its relevant subject matter and the lecturers’ language cognition as L2 users.
6
Lean, Jonathan, Jonathan Moizer, Cathrine Derham, Lesley Strachan, and Zakirul Bhuiyan. "Real World Learning: Simulation and Gaming." In Applied Pedagogies for Higher Education, 187–214. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-46951-1_9.
Full textAbstract:
Abstract Simulations and games are being used across a variety of subject areas as a means to provide insight into real world situations within a classroom setting; they offer many of the benefits of real world learning but without some of the associated risks and costs. Lean, Moizer, Derham, Strachan and Bhuiyan aim to evaluate the role of simulations and games in real world learning. The nature of simulations and games is discussed with reference to a variety of examples in Higher Education. Their role in real world learning is evaluated with reference to the benefits and challenges of their use for teaching and learning in Higher Education. Three case studies from diverse subject contexts are reported to illustrate the use of simulations and games and some of the associated issues.
7
Marcus, Pamela M. "Observational Research Designs." In Assessment of Cancer Screening, 79–100. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-94577-0_7.
Full textAbstract:
AbstractObservational studies do not dictate the cancer screening regimens that their study subjects utilize. Instead, these studies collect data on individuals’ cancer screening practices, cancer outcomes, and other factors if needed. Because no regimens are dictated, an observational study can capture information about and evaluate a variety of cancer screening practices, including use of different tests or cancer screening regimens. Observational studies can be retrospective or prospective in nature, with the distinction dependent on how and when individuals are chosen for study inclusion. Observational studies provide weaker evidence than experimental studies because observational studies are subject to confounding. Confounding occurs when a third factor is associated with both the cancer screening practice and cause-specific mortality, meaning that the third factor is not equally present among groups of individuals with different cancer screening practices and is not equally present among groups of individuals with different cancer outcomes.
8
Scheible, Raphael, Philip Strecker, Suhail Yazijy, Fabian Thomczyk, Ruslan Talpa, Andrea Puhl, and Martin Boeker. "A Multilingual Browser Platform for Medical Subject Headings." In Studies in Health Technology and Informatics. IOS Press, 2022. http://dx.doi.org/10.3233/shti210939.
Full textAbstract:
The National Library of Medicine (NLM) controls and publishes the thesaurus Medical Subject Headings which is used for indexing PubMed. Besides an XML export, the NLM offers a web based MeSH browser. The platform contains English terms. The German Institute for Medical Documentation and Information (DIMDI) partially translated and published these terms. Recently, the German National Library of Medicine (ZB-MED) overtook the translation of MeSH. However, there is no dedicated platform which focuses on MeSH and covers multiple languages. Here, we address this gap, by offering a modern multilingual searchable MeSH browser. A modular platform using open source technology is presented. The frontend enables the user to search and browse terms and switch between different languages. The current version of the presented MeSH browser contains English and German MeSH terms and can be accessed at https://mesh-browser.de.
9
Ulrich, Hannes, Hristina Uzunova, Heinz Handels, and Josef Ingenerf. "Proposal of Semantic Annotation for German Metadata Using Bidirectional Recurrent Neural Networks." In Studies in Health Technology and Informatics. IOS Press, 2022. http://dx.doi.org/10.3233/shti220474.
Full textAbstract:
The distributed nature of our digital healthcare and the rapid emergence of new data sources prevents a compelling overview and the joint use of new data. Data integration, e.g., with metadata and semantic annotations, is expected to overcome this challenge. In this paper, we present an approach to predict UMLS codes to given German metadata using recurrent neural networks. The augmentation of the training dataset using the Medical Subject Headings (MeSH), particularly the German translations, also improved the model accuracy. The model demonstrates robust performance with 75% accuracy and aims to show that increasingly sophisticated machine learning tools can already play a significant role in data integration.
10
Moen, Hans, Henry Suhonen, Sanna Salanterä, Tapio Salakoski, and Laura-Maria Peltonen. "Clustering Nursing Sentences – Comparing Three Sentence Embedding Methods." In Studies in Health Technology and Informatics. IOS Press, 2022. http://dx.doi.org/10.3233/shti220606.
Full textAbstract:
In health sciences, high-quality text embeddings may augment qualitative data analysis of large amounts of text by enabling, e.g., searching and clustering of health information. This study aimed to evaluate three different sentence-level embedding methods in clustering sentences in nursing narratives from individual patients’ hospital care episodes. Two of these embeddings are generated from language models based on the BERT framework, and the third on the Sent2Vec method. These embedding methods were used to cluster sentences from 20 patient care episodes and the results were manually evaluated. Findings suggest that the best clusters were produced by the embeddings from a BERT model fine-tuned for the proxy task of predicting subject headings for nursing text.
Conference papers on the topic "Subject headings Use studies"
1
Monteiro, Lucas Nascimento, and Marcella Braz. "Postoperative migration of motor activity in low-grade glioma resection: a systematic review." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.473.
Full textAbstract:
Introduction: Compensatory mechanisms resulting from the phenomenon of neuroplasticity are present in patients with neuroepithelial tumors, such as lowgrade gliomas (LGG). In the case of tumors located in the primary motor cortex, neural reorganization of motor activity to other areas of the brain may favor the maintenance of motor activity and avoid neurological deficits. Thus, this study sought to assess the movement of motor activity in patients with LGG. Materials and Methods: The search strategy used medical subject headings and text words related to neuroplasticity, LGG, and primary motor cortex. The PubMed and Biblioteca Virtual em Saúde databases were used. The search of articles was conducted from November 2020 to January 2021, and there was no time limit regarding article eligibility. Results: Four studies were included following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The contralateral motor and supplementary areas were the most active areas reported in the postoperative period. Given that this was a retrospective study, it did not demonstrate migration of motor activity, making surgical resection unfeasible. Conclusion: Knowing where motor function migration frequently occurs in patients with LGG is useful to optimize the resection of these tumors without inducing neurological deficits, thereby increasing the quality of resection in critical areas, such as the primary motor cortex.
2
David, Prof Maya, and Dr Francisco Perlas Dumanig. "Border Crossings: Use of Linguistic Studies across Subject Disciplines." In Annual International Conference on Language, Literature and Linguistics. Global Science & Technology Forum (GSTF), 2015. http://dx.doi.org/10.5176/2251-3566_l315.70.
Full text
3
Vincent Andersen, Ingrid Marie, and Gaute Storhaug. "Dynamic Selection of Ship Responses for Estimation of On-Site Directional Wave Spectra." In ASME 2012 31st International Conference on Ocean, Offshore and Arctic Engineering. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/omae2012-83206.
Full textAbstract:
Knowledge of the wave environment in which a ship is operating is crucial for most on-board decision support systems. Previous research has shown that the directional wave spectrum can be estimated by the use of measured global ship responses and a set of transfer functions determined for the specific ship. The approach can either be based on parametric or Bayesian (non-parametric) modelling, and in both cases a set of three ship responses usually provides the best estimation. The optimal response combination of three responses at any time depends on the environmental conditions and the operation of the ship. Since measurements of more than three responses are usually available, a quick, dynamic selection procedure of the three signals best suited for the wave spectrum estimation procedure is essential. In the present paper the concept of a selection method based on a simple pre-estimate of the wave spectrum is suggested. The selection method needs to be robust for what reason a parameterised uni-directional, two-parameter wave spectrum is treated. The parameters included are the zero up-crossing period, the significant wave height and the main wave direction relative to the ship’s heading. The procedure basically seeks to minimise the difference between a set of spectral moments derived from a measured response spectrum and the corresponding response spectrum calculated from the parameterised wave spectrum and the transfer function for any given response. Subsequently, the three responses with the best overall agreement are selected for the actual estimation of the directional wave spectrum. The transfer functions for the ship responses can be determined using different computational methods such as striptheory, 3D panel codes, closed form expressions or model tests. The uncertainty associated with transfer functions depends on the computational method used, relative heading, frequency and type of response. This uncertainty is conceptually taken into account in the selection procedure using the First Order Reliability Method (FORM). However, specific assessment of the uncertainties has not been carried out, but is subject to later studies.
4
Kozitsyn, Aleksandr Sergeevich, Sergey Alexandrovich Afonin, and Dmitry Alexeevich Shachnev. "Algorithm for Searching Experts in Scientometric Systems." In 23rd Scientific Conference “Scientific Services & Internet – 2021”. Keldysh Institute of Applied Mathematics, 2021. http://dx.doi.org/10.20948/abrau-2021-6-ceur.
Full textAbstract:
The use of modern methods of thematic analysis for the analytical processing of large amounts of information is currently used in almost all spheres of human activity. Scientometrics is one such area. Research carried out in this area shows that the statistical characteristics of citation rates are highly dependent on the thematic area of papers at hand. In this regard, systems for calculating citation indicators and constructing assessments of the quality of scientific works, ranks of authors or organizations should take into account the thematic area of researchers in order to normalize scientometric indicators. Many scientometric systems and citation systems use subject headings for information retrieval and processing. The world famous citation systems, including WoS, Scopus, Google Shcolar, and others have such headings. Important practical tasks that can be solved using the methods of thematic classification are: assessment of the dynamics of the development of thematic areas in an organization, in a particular country and in world science as a whole; search for articles on a given topic; search and assessment of the authority of experts; search for journals for publication and other urgent tasks. The authors have created software implementations of algorithms for solving some of the listed problems, and research is being conducted to create new effective mathematical models and algorithms in this area.
5
Черепова, Ю. В. "THE METHODICAL APPROACH TO EXPLICIT KNOWLEDGE MANAGEMENT IN UNIVERSITY." In XVII Российская конференция “Распределенные информационно-вычислительные ресурсы: Цифровые двойники и большие данные”. Crossref, 2019. http://dx.doi.org/10.25743/ict.2019.12.61.035.
Full textAbstract:
В исследовании на здоровых лицах и пациентах показана дискретная динамика статистических параметров механизмов регуляции сердечно-сосудистой системы при нагрузочных пробах. Предложено в качестве индикатора надёжности организма использовать сохранность механизма поддержания неравновесной устойчивости на уровнях, соответствующих возмущениям, воздействующим на организм. Currently, the knowledge description problem in scientific organizations is relevant. One of the consequences of a successful knowledge description is an reasoned choice of employees to work execution. The article presents a methodological approach to explicit knowlege management of university employees, which allowsвуеукьш you to make the effective management decisions. The methodological approach is based on the use of two methods. The first method allows us to determine the desired competencies and scientific results of employees necessary for the successful project implementation. The second method allows us to describe the fact competencies and scientific results of university employees and the specific tasks of projects in terms of a unified language of subject headings.
6
Гаврилова, Е. А., Л. К. Бобров, and И. Т. Утепбергенов. "INFORMATION SUPPORT SYSTEM FOR INNOVATIONS IN KAZAKHSTAN: METADATA INPUT SUBSYSTEM." In XVII Российская конференция “Распределенные информационно-вычислительные ресурсы: Цифровые двойники и большие данные”. Crossref, 2019. http://dx.doi.org/10.25743/ict.2019.48.26.010.
Full textAbstract:
Дается краткая характеристика проекта создания системы информационного обеспечения инновационной экономики Казахстана. Приводится состав подсистем и их краткое описание. Формулируются требования к подсистеме ввода информации. Раскрываются особенности структуры базы метаданных, описывающих мировые информационные ресурсы, релевантные задачам развития инновационной деятельности в Республике Казахстан. Описываются используемые справочники и тематические рубрикаторы. Приводятся диаграммы прецедентов, иллюстрирующие функции для различных типов пользователей. Дается пример интерфейса подсистемы ввода метаданных. Brief description of the project to create Information Support System for Innovative Economy in the Republic of Kazakhstan is given. Composition of subsystems and their brief description are given. Requirements for the information input subsystem are formulated. Features of the structure of the metadata base are revealed that describe world information resources that are relevant to the tasks of the development of innovative activity in the Republic of Kazakhstan. Description of directories and subject headings are described. Use case diagrams illustrating functions for different types of users are provided. Example metadata input subsystem interface is presented.
7
Schiller, Rafael Vergara, Csaba Pâkozdi, Carl Trygve Stansberg, Douglas Gustavo Takashi Yuba, and Daniel Fonseca de Carvalho e Silva. "Green Water on FPSO Predicted by a Practical Engineering Method and Validated Against Model Test Data for Irregular Waves." In ASME 2014 33rd International Conference on Ocean, Offshore and Arctic Engineering. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/omae2014-24084.
Full textAbstract:
This paper presents a series of numerical analyses performed with the potential theory-based Green Water engineer tool KINEMA3. KINEMA3 was designed to predict wave-induced impact loads on FPSOs in steep irregular waves, and for use in design load analysis. The purpose of the study presented herein is to validate KINEMA3 green water (deck overtopping) predictions in nonlinear irregular waves with results from model tests performed at the TPN (Tanque de Provas Numérico) laboratory at the University of São Paulo, Brazil. Comparisons are made for a selection of irregular wave cases, for two choices of anchoring conditions (free floating vessel and fixed vessel) and for three wave headings (180°, 225° and 270°: head, quartering and beam seas, respectively). KINEMA3 statistical green water predictions present a general good agreement with observations from the TPN model tests for all wave cases, headings and mooring conditions. Overall, observed trends for occurrence of green water and standard deviation/maximum of relative wave height are successfully reproduced by KINEMA3. In agreement with model test results, it is predicted that green water occurs more frequently for a free floating vessel and for beam seas. Additional comparisons between KINEMA3 predictions using different FPSO panel models (low-order and high-order models) present negligible differences with respect to green water estimates. The results presented herein demonstrate the robustness of the tool towards the prediction of green water for variable wave headings and sea states, and highlight the capability of KINEMA3 to be employed as an engineering-like tool for fast and multiple estimates of green water in early design studies. This work is a part of the research project “Green Water and Wave Impact on FPSO” carried out for and in cooperation with PETROBRAS.
8
Harraway, John, Bryan Manly, Hilary Sutherland, and Allan McRae. "Meeting the statistical needs of researchers in the biological and health sciences." In Training Researchers in the Use if Statistics. International Association for Statistical Education, 2000. http://dx.doi.org/10.52041/srap.00301.
Full textAbstract:
The results of a survey on the use of statistics in research in five subject areas representative of the biological and health sciences are reported. The main component of the survey is a review of statistical methods in 2927 research papers published during 1999 in 16 high impact journals from botany, ecology, food science, marine science and nutrition. A factor analysis establishes that research papers in the different subject areas use different methods. The opinions of research staff and postgraduate students working in these areas are also reported. To support these opinions we provide details of five postgraduate studies involving advanced statistical analyses, which have either resulted in publication or should result in publication in the near future. Discussion develops recommendations about topics important in a statistics curriculum for research students, where statistics courses should be taught, what is needed in terms of level of theory, the use of short courses and workshops, and the value of project work.
9
Drușan, Denis-Andrei, Ana-Maria Ciobanu, Mădălina Ignat, Roxana Constantinescu, Ciprian Chelaru, Vlad Bărbulescu, and Angela Chelu. "Studies Regarding Structural Properties of Chemical Industry Equipment." In The 9th International Conference on Advanced Materials and Systems. INCDTP - Leather and Footwear Research Institute (ICPI), Bucharest, Romania, 2022. http://dx.doi.org/10.24264/icams-2022.iii.9.
Full textAbstract:
An adequate and optimized equipment plays a very important role in the chemical industry. Due to the way an equipment is designed, it can be subject to certain types of structural deformations. This aim of this study is to show the importance of fortifies openings that are made to connect the pipes with pressure vessels. The development of chemical and petrochemical installations led to the need for continuous research of the vessel’s coatings for a better understanding of design of these structures to be operate in maximum safety. The openings contribute to destabilization of structure for a pressure vessel and make it dangerous to use.
10
Farhi, Nadir, Julien Christian Marck, Aniket Sanyal, Mohamed Ahmed Abdel Samie, Moataz Mahmoud Eldemerdash, Ali Hussein Safar, Mohamed Jassem Al-Khaja, et al. "Remote Drilling Solution Delivers Consistency with the Use of an Automated Drilling Director: Case Studies from Kuwait." In Abu Dhabi International Petroleum Exhibition & Conference. SPE, 2021. http://dx.doi.org/10.2118/207866-ms.
Full textAbstract:
Abstract The Automated Drilling Director, a software application for drilling automation, integrates a physics-based model of the drilling system with machine learning and optimization algorithms to project the well path, monitor collision risk, manage vibrations, and control steering in real time automatically. With "intelligent" rotary steerable systems (RSSs), these steering decisions can be downlinked directly to the tool, thus, fully closing the loop around steering decision-making. Implementation of the Automated Drilling Director within a remote drilling center (RDC) enables the drilling operations to be conducted remotely and effectively with less rig site personnel. The resulting decisions are consistent and reliable, while a team of subject matter experts (SMEs) monitor the operations to optimize well assets, ensuring that the pre-job design of service (DoS) is executed properly. The validation of this innovative technology and approach in Kuwait, amongst others, opens the door to a new way of doing business, where resources, experience, and data are combined in the most efficient manner to improve consistency, as well as to maximize the value of the operators’ assets.
Reports on the topic "Subject headings Use studies"
1
Qu, Pengda, Jing Huang, Shiqi Wang, Size Li, Qian Hu, Wei Wang, and Xiaohu Tang. Efficacy and safety of modified Ermiao decoction in the treatment of gouty arthritis: A protocol for systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, July 2022. http://dx.doi.org/10.37766/inplasy2022.7.0063.
Full textAbstract:
Review question / Objective: The purpose of this study is to comprehensively evaluate the efficacy and safety of modified Ermiao decoction in the treatment of gouty arthritis. Information sources: We will conduct searches of Web of Science, PubMed, Cochrane Library, Embase, China National Knowledge Infrastructure (CNKI), Wanfang Data Knowledge Service Platform (Wanfang), Weipu Chinese Science and Technology Journal Full-text Database (VIP), and Chinese Biomedical Literature Database (CBM) from their inception to July 2022. In addition, trial registration platforms will also be searched for ongoing or unpublished trials, including International Clinical Trials Registry Platform and Chinese Clinical Trial Registry Centre. The languages of included studies will be restricted in English and Chinese. Medical Subject Headings and free words terms will be used during the retrieval process. The main search terms include “gouty arthritis”, “modified Ermiao”, and “randomized controlled trial.” A draft of the PubMed search strategy is included in Table 1. Similar retrieval strategies will be applied to the other databases mentioned above. We will also search for relevant systematic reviews of using MED for GA and reference lists of eligible studies to improve recall ratio.
2
Bone, Christine. Changes to Library of Congress Subject Headings Related to Indigenous Peoples: for use in the AMA MAIN Database. AMA MAIN-LCSH Working Group, 2015. http://dx.doi.org/10.5203/ss_ama.main_bon.chr.2015.1.
Full text
3
Downes, Jane, ed. Chalcolithic and Bronze Age Scotland: ScARF Panel Report. Society for Antiquaries of Scotland, September 2012. http://dx.doi.org/10.9750/scarf.09.2012.184.
Full textAbstract:
The main recommendations of the panel report can be summarised under five key headings: Building the Scottish Bronze Age: Narratives should be developed to account for the regional and chronological trends and diversity within Scotland at this time. A chronology Bronze Age Scotland: ScARF Panel Report iv based upon Scottish as well as external evidence, combining absolute dating (and the statistical modelling thereof) with re-examined typologies based on a variety of sources – material cultural, funerary, settlement, and environmental evidence – is required to construct a robust and up to date framework for advancing research. Bronze Age people: How society was structured and demographic questions need to be imaginatively addressed including the degree of mobility (both short and long-distance communication), hierarchy, and the nature of the ‘family’ and the ‘individual’. A range of data and methodologies need to be employed in answering these questions, including harnessing experimental archaeology systematically to inform archaeologists of the practicalities of daily life, work and craft practices. Environmental evidence and climate impact: The opportunity to study the effects of climatic and environmental change on past society is an important feature of this period, as both palaeoenvironmental and archaeological data can be of suitable chronological and spatial resolution to be compared. Palaeoenvironmental work should be more effectively integrated within Bronze Age research, and inter-disciplinary approaches promoted at all stages of research and project design. This should be a two-way process, with environmental science contributing to interpretation of prehistoric societies, and in turn, the value of archaeological data to broader palaeoenvironmental debates emphasised. Through effective collaboration questions such as the nature of settlement and land-use and how people coped with environmental and climate change can be addressed. Artefacts in Context: The Scottish Chalcolithic and Bronze Age provide good evidence for resource exploitation and the use, manufacture and development of technology, with particularly rich evidence for manufacture. Research into these topics requires the application of innovative approaches in combination. This could include biographical approaches to artefacts or places, ethnographic perspectives, and scientific analysis of artefact composition. In order to achieve this there is a need for data collation, robust and sustainable databases and a review of the categories of data. Wider Worlds: Research into the Scottish Bronze Age has a considerable amount to offer other European pasts, with a rich archaeological data set that includes intact settlement deposits, burials and metalwork of every stage of development that has been the subject of a long history of study. Research should operate over different scales of analysis, tracing connections and developments from the local and regional, to the international context. In this way, Scottish Bronze Age studies can contribute to broader questions relating both to the Bronze Age and to human society in general.
4
Dong, Wei, Wei Zhang, Jianxu Er, Jiapeng Liu, and Jiange Han. Lesser complications of laryngeal mask airway than endotracheal tubes in pediatric airway management: A review of literature and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, May 2022. http://dx.doi.org/10.37766/inplasy2022.5.0066.
Full textAbstract:
Review question / Objective: The relevant expert consensus has not pointed out which ventilation device is better during general anesthesia in the pediatric airway management for elective surgery. Condition being studied: We carried out a keyword search using the terms “layngeal mask, LMA, endotracheal tube, tracheal tube, children, pediatric, anesthesia, RCT, randomized controlled trials, randomized, elective surgery.” In general, searches are developed in MEDLINE in Ovid; Embase.com; the Cochrane Central Register of Controlled Trials (CENTRAL) via the Wiley Interface; Web of Science Core Collection; PubMed restricting to records in the subset “as supplied by publisher” to find references that not yet indexed in MEDLINE; and Google Scholar. When available, these databases were searched using a combination of subject headings (such as MeSH) and filters (such as RCT). We reviewed references of included studies to identify relevant studies. We imposed no language or time restriction. The exact date of the database search is September 1, 2021.We carried out a keyword search using terms “layngeal mask, LMA, endotracheal tube, tracheal tube, children, pediatric, anesthesia, RCT, randomized controlled trials, randomized, elective surgery.”
5
Goncharenko, Tatiana, Nataliia Yermakova-Cherchenko, and Yelyzaveta Anedchenko. Experience in the Use of Mobile Technologies as a Physics Learning Method. [б. в.], November 2020. http://dx.doi.org/10.31812/123456789/4468.
Full textAbstract:
Swift changes in society, related to sciences technicians’ development, technologies, by the increase of general volume of information, pull out new requirements for maintenance, structure, and quality of education. It requires teachers to diversify a tool in the direction of the increase in possibilities of the use of mobile technologies and computer systems. Lately in the world, more attention spared to the use of mobile learning, which in obedience to «Recommendations of UNESCO on the questions of a policy in the area of mobile learning» foresees the use of mobile technology, both separate and together with other by informational computer technologies. [1]. Mobile learning allows using the open informational systems, global educational networks, unique digital resources which belong to different educational establishments and co-operate with each other. The use of existent educational resources and creation of own, based on the academic resources from informative space, allows to promote the interest of students to the study of physics, to take into account the individual features, and also features of region and framework of society of the country. During the last years in Ukraine competency-based approach to the organization of studies certainly one of basic. The new Education Act addresses the key competencies that every modern person needs for a successful life, including mathematical competence; competence in natural sciences, engineering, and technology; innovation; information and communication competence [2]. This further emphasizes the importance of providing students with quality physical education and the problems associated with it. Using mobile technology in professional teaching work, the teacher has the opportunity to implement the basic principles of the competence approach in teaching physics. An analysis of the data provided in the official reports of the Ukrainian Center for Educational Quality Assessment showed that the number of students making an external independent assessment in physics and choosing a future profession related to physics has decreased significantly. This is due to the loss of students' interest in physics and the complexity of the content of the subject, as well as the increase in the amount of information that students need to absorb. In this article, we explore the possibilities of mobile technology as a means of teaching physics students and give our own experience of using mobile technology in the process of teaching physics (for example, the optics section in primary school).
6
Chornodon, Myroslava. FEAUTURES OF GENDER IN MODERN MASS MEDIA. Ivan Franko National University of Lviv, February 2021. http://dx.doi.org/10.30970/vjo.2021.49.11064.
Full textAbstract:
The article clarifies of gender identity stereotypes in modern media. The main gender stereotypes covered in modern mass media are analyzed and refuted. The model of gender relations in the media is reflected mainly in the stereotypical images of men and woman. The features of the use of gender concepts in modern periodicals for women and men were determined. The most frequently used derivatives of these macroconcepts were identified and analyzed in detail. It has been found that publications for women and men are full of various gender concepts that are used in different contexts. Ingeneral, theanalysisofthe concept-maximums and concept-minimum gender and their characteristics is carried out in the context of gender stereotypes that have been forme dand function in the society, system atizing the a ctual presentations. The study of the gender concept is relevant because it reveals new trends and features of modern gender images. Taking into account the special features of gender-labeled periodicals in general and the practical absence of comprehensive scientific studies of the gender concept in particular, there is a need to supplement Ukrainian science with this topic. Gender psychology, which is served by methods of various sciences, primarily sociological, pedagogical, linguistic, psychological, socio-psychological. Let us pay attention to linguistic and psycholinguistic methods in gender studies. Linguistic methods complement intelligence research tasks, associated with speech, word and text. Psycholinguistic methods used in gender psychology (semantic differential, semantic integral, semantic analysis of words and texts), aimed at studying speech messages, specific mechanisms of origin and perception, functions of speech activity in society, studying the relationship between speech messages and gender properties participants in the communication, to analyze the linguistic development in connection with the general development of the individual. Nowhere in gender practice there is the whole arsenal of psychological methods that allow you to explore psychological peculiarities of a person like observation, experiments, questionnaires, interviews, testing, modeling, etc. The methods of psychological self-diagnostics include: the gender aspect of the own socio-psychological portrait, a gender biography as a variant of the biographical method, aimed at the reconstruction of individual social experience. In the process of writing a gender autobiography, a person can understand the characteristics of his gender identity, as well as ways and means of their formation. Socio-psychological methods of studying gender include the study of socially constructed women’s and men’s roles, relationships and identities, sexual characteristics, psychological characteristics, etc. The use of gender indicators and gender approaches as a means of socio-psychological and sociological analysis broadens the subject boundaries of these disciplines and makes them the subject of study within these disciplines. And also, in the article a combination of concrete-historical, structural-typological, system-functional methods is implemented. Descriptive and comparative methods, method of typology, modeling are used. Also used is a method of content analysis for the study of gender content of modern gender-stamped journals. It was he who allowed quantitatively to identify and explore the features of the gender concept in the pages of periodicals for women and men. A combination of historical, structural-typological, system-functional methods is also implemented in the article. Descriptive and comparative methods, method of typology, modeling are used. A method of content analysis for the study of gender content of modern gender-labeled journals is also used. It allowed to identify and explore the features of the gender concept quantitatively in the periodicals for women and men. The conceptual perception and interpretation of the gender concept «woman», which is highlighted in the modern gender-labeled press in Ukraine, requires the elaboration of the polyfunctionality of gender interpretations, the comprehension of the metaphorical perception of this image and its role and purpose in society. A gendered approach to researching the gender content of contemporary periodicals for women and men. Conceptual analysis of contemporary gender-stamped publications within the gender conceptual sphere allows to identify and correlate the meta-gender and gender concepts that appear in society.
7
Tanny, Josef, Gabriel Katul, Shabtai Cohen, and Meir Teitel. Application of Turbulent Transport Techniques for Quantifying Whole Canopy Evapotranspiration in Large Agricultural Structures: Measurement and Theory. United States Department of Agriculture, January 2011. http://dx.doi.org/10.32747/2011.7592121.bard.
Full textAbstract:
Original objectives and revisions The original objectives of this research, as stated in the approved proposal were: 1. To establish guidelines for the use of turbulent transport techniques as accurate and reliable tool for continuous measurements of whole canopy ET and other scalar fluxes (e.g. heat and CO2) in large agricultural structures. 2. To conduct a detailed experimental study of flow patterns and turbulence characteristics in agricultural structures. 3. To derive theoretical models of air flow and scalar fluxes in agricultural structures that can guide the interpretation of TT measurements for a wide range of conditions. All the objectives have been successfully addressed within the project. The only modification was that the study focused on screenhouses only, while it was originally planned to study large greenhouses as well. This was decided due to the large amount of field and theoretical work required to meet the objectives within screenhouses. Background In agricultural structures such as screenhouses and greenhouses, evapotranspiration (ET) is currently measured using lysimeters or sap flow gauges. These measurements provide ET estimates at the single-plant scale that must then be extrapolated, often statistically or empirically, to the whole canopy for irrigation scheduling purposes. On the other hand, turbulent transport techniques, like the eddy covariance, have become the standard for measuring whole canopy evapotranspiration in the open, but their applicability to agricultural structures has not yet been established. The subject of this project is the application of turbulent transport techniques to estimate ET for irrigation scheduling within large agricultural structures. Major conclusions and achievements The major conclusions of this project are: (i) the eddy covariance technique is suitable for reliable measurements of scalar fluxes (e.g., evapotranspiration, sensible heat, CO2) in most types of large screenhouses under all climatic conditions tested. All studies resulted with fair energy balance closures; (ii) comparison between measurements and theory show that the model is capable in reliably predicting the turbulent flow characteristics and surface fluxes within screenhouses; (iii) flow characteristics within the screenhouse, like flux-variance similarity and turbulence intensity were valid for the application of the eddy covariance technique in screenhouses of relatively dilute screens used for moderate shading and wind breaking. In more dense screens, usually used for insect exclusions, development of turbulent conditions was marginal; (iv) installation of the sensors requires that the system’s footprint will be within the limits of the screenhouse under study, as is the case in the open. A footprint model available in the literature was found to be reliable in assessing the footprint under screenhouse conditions. Implications, both scientific and agricultural The study established for the first time, both experimentally and theoretically, the use of the eddy covariance technique for flux measurements within agricultural screenhouses. Such measurements, along with reliable theoretical models, will enable more accurate assessments of crop water use which may lead to improved crop water management and increased water use efficiency of screenhouse crops.
8
Hunter, Fraser, and Martin Carruthers. Iron Age Scotland. Society for Antiquaries of Scotland, September 2012. http://dx.doi.org/10.9750/scarf.09.2012.193.
Full textAbstract:
The main recommendations of the panel report can be summarised under five key headings: Building blocks: The ultimate aim should be to build rich, detailed and testable narratives situated within a European context, and addressing phenomena from the longue durée to the short-term over international to local scales. Chronological control is essential to this and effective dating strategies are required to enable generation-level analysis. The ‘serendipity factor’ of archaeological work must be enhanced by recognising and getting the most out of information-rich sites as they appear. o There is a pressing need to revisit the archives of excavated sites to extract more information from existing resources, notably through dating programmes targeted at regional sequences – the Western Isles Atlantic roundhouse sequence is an obvious target. o Many areas still lack anything beyond the baldest of settlement sequences, with little understanding of the relations between key site types. There is a need to get at least basic sequences from many more areas, either from sustained regional programmes or targeted sampling exercises. o Much of the methodologically innovative work and new insights have come from long-running research excavations. Such large-scale research projects are an important element in developing new approaches to the Iron Age. Daily life and practice: There remains great potential to improve the understanding of people’s lives in the Iron Age through fresh approaches to, and integration of, existing and newly-excavated data. o House use. Rigorous analysis and innovative approaches, including experimental archaeology, should be employed to get the most out of the understanding of daily life through the strengths of the Scottish record, such as deposits within buildings, organic preservation and waterlogging. o Material culture. Artefact studies have the potential to be far more integral to understandings of Iron Age societies, both from the rich assemblages of the Atlantic area and less-rich lowland finds. Key areas of concern are basic studies of material groups (including the function of everyday items such as stone and bone tools, and the nature of craft processes – iron, copper alloy, bone/antler and shale offer particularly good evidence). Other key topics are: the role of ‘art’ and other forms of decoration and comparative approaches to assemblages to obtain synthetic views of the uses of material culture. o Field to feast. Subsistence practices are a core area of research essential to understanding past society, but different strands of evidence need to be more fully integrated, with a ‘field to feast’ approach, from production to consumption. The working of agricultural systems is poorly understood, from agricultural processes to cooking practices and cuisine: integrated work between different specialisms would assist greatly. There is a need for conceptual as well as practical perspectives – e.g. how were wild resources conceived? o Ritual practice. There has been valuable work in identifying depositional practices, such as deposition of animals or querns, which are thought to relate to house-based ritual practices, but there is great potential for further pattern-spotting, synthesis and interpretation. Iron Age Scotland: ScARF Panel Report v Landscapes and regions: Concepts of ‘region’ or ‘province’, and how they changed over time, need to be critically explored, because they are contentious, poorly defined and highly variable. What did Iron Age people see as their geographical horizons, and how did this change? Attempts to understand the Iron Age landscape require improved, integrated survey methodologies, as existing approaches are inevitably partial. Aspects of the landscape’s physical form and cover should be investigated more fully, in terms of vegetation (known only in outline over most of the country) and sea level change in key areas such as the firths of Moray and Forth. Landscapes beyond settlement merit further work, e.g. the use of the landscape for deposition of objects or people, and what this tells us of contemporary perceptions and beliefs. Concepts of inherited landscapes (how Iron Age communities saw and used this longlived land) and socal resilience to issues such as climate change should be explored more fully. Reconstructing Iron Age societies. The changing structure of society over space and time in this period remains poorly understood. Researchers should interrogate the data for better and more explicitly-expressed understandings of social structures and relations between people. The wider context: Researchers need to engage with the big questions of change on a European level (and beyond). Relationships with neighbouring areas (e.g. England, Ireland) and analogies from other areas (e.g. Scandinavia and the Low Countries) can help inform Scottish studies. Key big topics are: o The nature and effect of the introduction of iron. o The social processes lying behind evidence for movement and contact. o Parallels and differences in social processes and developments. o The changing nature of houses and households over this period, including the role of ‘substantial houses’, from crannogs to brochs, the development and role of complex architecture, and the shift away from roundhouses. o The chronology, nature and meaning of hillforts and other enclosed settlements. o Relationships with the Roman world
9
Gidengil, Courtney, Matthew Bidwell Goetz, Margaret Maglione, Sydne J. Newberry, Peggy Chen, Kelsey O’Hollaren, Nabeel Qureshi, et al. Safety of Vaccines Used for Routine Immunization in the United States: An Update. Agency for Healthcare Research and Quality (AHRQ), May 2021. http://dx.doi.org/10.23970/ahrqepccer244.
Full textAbstract:
Objective. To conduct a systematic review of the literature on the safety of vaccines recommended for routine immunization in the United States, updating the 2014 Agency for Healthcare Research and Quality (AHRQ) report on the topic. Data sources. We searched MEDLINE®, Embase®, CINAHL®, Cochrane CENTRAL, Web of Science, and Scopus through November 9, 2020, building on the prior 2014 report; reviewed existing reviews, trial registries, and supplemental material submitted to AHRQ; and consulted with experts. Review methods. This report addressed three Key Questions (KQs) on the safety of vaccines currently in use in the United States and included in the Centers for Disease Control and Prevention’s (CDC) recommended immunization schedules for adults (KQ1), children and adolescents (KQ2), and pregnant women (KQ3). The systematic review was supported by a Technical Expert Panel that identified key adverse events of particular concern. Two reviewers independently screened publications; data were extracted by an experienced subject matter expert. Studies of vaccines that used a comparator and reported the presence or absence of adverse events were eligible. We documented observed rates and assessed the relative risks for key adverse events. We assessed the strength of evidence (SoE) across the existing findings from the prior 2014 report and the new evidence from this update. The systematic review is registered in PROSPERO (CRD42020180089). Results. A large body of evidence is available to evaluate adverse events following vaccination. Of 56,608 reviewed citations, 189 studies met inclusion criteria for this update, adding to data in the prior 2014 report, for a total of 338 included studies reported in 518 publications. Regarding vaccines recommended for adults (KQ1), we found either no new evidence of increased risk for key adverse events with varied SoE or insufficient evidence in this update, including for newer vaccines such as recombinant influenza vaccine, adjuvanted inactivated influenza vaccine, and recombinant adjuvanted zoster vaccine. The prior 2014 report noted a signal for anaphylaxis for hepatitis B vaccines in adults with yeast allergy and for tetanus, diphtheria, and acellular pertussis vaccines. Regarding vaccines recommended for children and adolescents (KQ2), we found either no new evidence of increased risk for key adverse events with varied SoE or insufficient evidence, including for newer vaccines such as 9-valent human papillomavirus vaccine and meningococcal B vaccine. The prior 2014 report noted signals for rare adverse events—such as anaphylaxis, idiopathic thrombocytopenic purpura, and febrile seizures—with some childhood vaccines. Regarding vaccines recommended for pregnant women (KQ3), we found no evidence of increased risk for key adverse events with varied SoE among either pregnant women or their infants following administration of tetanus, diphtheria, and acellular pertussis vaccines during pregnancy. Conclusion. Across this large body of research, we found no new evidence of increased risk since the prior 2014 report for key adverse events following administration of vaccines that are routinely recommended. Signals from the prior report remain unchanged for rare adverse events, which include anaphylaxis in adults and children, and febrile seizures and idiopathic thrombocytopenic purpura in children. There is no evidence of increased risk of adverse events for vaccines currently recommended in pregnant women. There remains insufficient evidence to draw conclusions about some rare potential adverse events.
10
Steffens, John C., and Eithan Harel. Polyphenol Oxidases- Expression, Assembly and Function. United States Department of Agriculture, January 1995. http://dx.doi.org/10.32747/1995.7571358.bard.
Full textAbstract:
Polyphenol oxidases (PPOs) participate in the preparation of many plant products on the one hand and cause considerable losses during processing of plant products on the other hand. However, the physiological functions of plant PPO were still a subject of controversy at the onset of the project. Preliminary observations that suggested involvement of PPOs in resistance to herbivores and pathogens held great promise for application in agriculture but required elucidation of PPO's function if modulation of PPO expression is to be considered for improving plant protection or storage and processing of plant products. Suggestions on a possible role of PPO in various aspects of chloroplast metabolism were also relevant in this context. The characterization of plant PPO genes opened a way for achieving these goals. We reasoned that "understanding PPO targeting and routing, designing ways to manipulate its expression and assessing the effects of such modifications will enable determination of the true properties of the enzyme and open the way for controlling its activity". The objective of the project was to "obtain an insight into the function and biological significance of PPOs" by examining possible function(s) of PPO in photosynthesis and plant-pest interactions using transgenic tomato plants; extending our understanding of PPO routing and assembly and the mechanism of its thylakoid translocation; preparing recombinant PPOs for use in import studies, determination of the genuine properties of PPOs and understanding its assembly and determining the effect of PPO's absence on chloroplast performance. Results obtained during work on the project made it necessary to abandon some minor objectives and devote the effort to more promising topics. Such changes are mentioned in the 'Body of the report' which is arranged according to the objectives of the original proposal. The complex expression pattern of tomato PPO gene family was determined. Individual members of the family are differentially expressed in various parts of the plant and subjected to developmentally regulated turnover. Some members are differentially regulated also by pathogens, wounding and chemical wound signals. Wounding systemically induces PPO activity and level in potato. Only tissues that are developmentally competent to express PPO are capable of responding to the systemic wounding signal by increased accumulation of PPO mRNA. Down regulation of PPO genes causes hyper susceptibility to leaf pathogens in tomato while over expression regulation of PPO expression in tomato plants is their apparent increased tolerance to drought. Both the enhanced disease resistance conferred by PPO over expression and the increased stress tolerance due to down regulation can be used in the engineering of improved crop plants. Photosynthesis rate and variable fluorescence measurements in wild type, and PPO-null and over expressing transgenic tomato lines suggest that PPO does not enable plants to cope better with stressful high light intensities or reactive oxygen species. Rather high levels of the enzyme aggravate the damage caused under such conditions. Our work suggests that PPO's primary role is in defending plants against pathogens and herbivores. Jasmonate and ethylene, and apparently also salicylate, signals involved in responses to wounding and defense against herbivores and pathogens, enhance markedly and specifically the competence of chloroplasts to import and process pPPO. The interaction of the precursor with thylakoid membranes is primarily affected. The routing of PPO shows other unusual properties: stromal processing occurs in two sites, resulting in intermediates that are translocated across thylakoids by two different mechanisms - a DpH- and a Sec-dependent one. It is suggested that the dual pattern of processing and routing constitutes a'fail safe' mechanism, reflecting the need for a rapid and flexible response to defense challenges. Many of the observations described above should be taken into consideration when manipulation of PPO expression is contemplated for use in crop improvement.