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1

S, Girish, Kuber Sankh, and Nataraj H R. "REVIEW ON KATAKA (STRYCHNOS POTATORUM LINN)." International Journal of Research in Ayurveda & Pharmacy 6, no. 1 (February 27, 2015): 86–89. http://dx.doi.org/10.7897/2277-4343.06119.

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2

D., Ravivarma, Ch Bhargavi, M. Manasa, G. Vaishnavi, and K. Chandramohan. "Morphology, Pharmacognosy of Strychnos nux-vomica and S. potatorum and their Medicinal Importance in Traditional Systems: A Review." Environment and Ecology 41, no. 4D (December 2023): 3022–28. http://dx.doi.org/10.60151/envec/mqyn5408.

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The species Strychnos nux-vomica and Strychnos potatorum Linn., which belong to the Loganiaceae family, are used in traditional medicine to treat gonorrhoea, leukorrhea, gastropathy, bronchitis, chronic diarrhoea, dysentery, renal and vesicle calculi, diabetes, conjunctivitis, scleritis, ulcers, and other eye diseases. This medicinal species has been highlighted in an effort through pharmacological and phytochemical research. The morphology, phenology, distribution, phytochemical analysis, and pharmacological screening of Strychnos potatorum and nux-vomica, two significant medicinal plants, are the subjects of the current review. The gathered data may serve as the foundation for its widespread application as a therapeutic agent in both conventional and alternative medicine.
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3

Sanmuga, Priya E., and S. Venkataraman. "Pharmacognostical And Phytochemical Studies Of Strychnos Potatorum Linn Seeds." Pharmacognosy Journal 2, no. 8 (May 2010): 190–97. http://dx.doi.org/10.1016/s0975-3575(10)80091-4.

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4

Savali, AnilSidram, UmeshJayantarao Patil, and ManjunathC Jirankali. "Antianaphylactic and mast cell stabilization activity of Strychnos potatorum Linn. seed." Pharmacognosy Research 3, no. 3 (2011): 208. http://dx.doi.org/10.4103/0974-8490.85011.

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5

Sanmugapriya, Ekambaram, and Subramanian Venkataraman. "Toxicological Investigations on Strychnos potatorum Linn Seeds in Experimental Animal Models." JOURNAL OF HEALTH SCIENCE 52, no. 4 (2006): 339–43. http://dx.doi.org/10.1248/jhs.52.339.

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6

Kumudhaveni, B., Dr R. Radha, and Dr A. Jerad Suresh. "Pharmacognostical and phytochemical standardization of seeds of Strychnos potatorum Linn. (Loganiaceae)." Journal of Pharmacognosy and Phytochemistry 9, no. 2 (March 1, 2020): 2054–59. http://dx.doi.org/10.22271/phyto.2020.v9.i2ah.11157.

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7

Sanmugapri, E., and S. Venkataram. "Antinociceptive and Antipyretic Effects of Strychnos potatorum Linn. Seeds on Experimental Rats." International Journal of Pharmacology 6, no. 5 (August 15, 2010): 681–85. http://dx.doi.org/10.3923/ijp.2010.681.685.

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8

Sanmugapriya, E., and S. Venkataraman. "Antiulcerogenic potential of Strychnos potatorum Linn seeds on Aspirin plus pyloric ligation-induced ulcers in experimental rats." Phytomedicine 14, no. 5 (May 2007): 360–65. http://dx.doi.org/10.1016/j.phymed.2006.12.025.

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9

Kirupa Sankar, M., K. Muthu Kumar, and B. V. Ranganathan. "Adsorption of anionic azo dye from aqueous solution using Strychnos potatorum Linn seeds: isotherm and kinetic studies." International Journal of Environmental Science and Technology 12, no. 9 (August 28, 2014): 2957–64. http://dx.doi.org/10.1007/s13762-014-0668-y.

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10

Sharma, Neeru, Yadevendra Yadav, and KhemChand Sharma. "A systemic review on Ayurvedic and modern pharmacology of Strychnos potatorum Linn. to determine its therapeutic potential." National Journal of Pharmacology and Therapeutics 1, no. 3 (2023): 125. http://dx.doi.org/10.4103/njpt.njpt_32_23.

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11

Sanmugapriya, E., and S. Venkataraman. "Studies on hepatoprotective and antioxidant actions of Strychnos potatorum Linn. seeds on CCl4-induced acute hepatic injury in experimental rats." Journal of Ethnopharmacology 105, no. 1-2 (April 2006): 154–60. http://dx.doi.org/10.1016/j.jep.2005.10.028.

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12

Sarangi, Manohar S., Hiremath S. K., Danappagoudar Girish, and Basavaraj Mulkipatil. "EVALUATION OF NEPHROPROTECTIVE ACTIVITY OF KATAKABEEJA YOGA AGAINST ASPIRIN-INDUCED NEPHROTOXICITY IN WISTAR RATS." International Ayurvedic Medical Journal p6, no. 1 (November 25, 2021): 3208–18. http://dx.doi.org/10.46607/iamj08p6012021.

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Drug-induced toxicity is the major concern in the present Era, particularly with Hepato and Nephrotoxicity. Drug- induced renal failure (RF) accounted for 20% in India. As there is an increasing number of potent therapeutics drugs like – NSAID's (Aspirin), Antibiotics, chemotherapy agents etc. Katakabeeja Yoga is mainly indicated in Prameha Chikitsa according to Yogaratnakar. Kataka (Strychnos potatorum. Linn) is Vishaghna, Ashmari, Prameha, Visha etc. Kataka - Independently have potent Antioxidant, Osmotic diuretic activity. Hence the pre- sent study was aimed to evaluate the Nephroprotective activity of Katakabeeja Yoga against Aspirin-induced Ne- phrotoxicity in Wistar rats. Katakabeeja Yoga was prepared after authenticating procured raw drugs and analyzed for preliminary physicochemical, organic and inorganic tests. Either sex Wistar rats weighing 150 – 200 g were selected and randomized into three groups (each group 6 no.) like Normal, Aspirin-induced, or Katakabeeja Yoga treated. Toxicity with Aspirin 100mg/kg orally for 15 days. In the treated group Katakabeeja yoga 0.216g (216mg) was received after administration of Aspirin for 15 days and sacrificed on the 16th day. Before and end of the study, the blood sample was collected for estimation of biomarkers like Serum Creatinine, urea and electro- lytes. The kidney was kept in a 10% formalin solution and sent for histopathology studies. Data were analyzed by one way ANOVA and Tukey's multiple post hoc procedures. The Aspirin group showed a significant rise in se- rum Creatinine, and urea followed by a decrease the urine output. Katakabeeja Yoga significantly reduced the serum Creatinine and urea followed by an increase in the urine output may have Katakabeeja potent antioxidant, osmotic diuretic activity. The study established that Katakabeeja Yoga possesses a durable Nephroprotective ef- fect against Aspirin-induced Nephrotoxicity. Keywords: Nephroprotective, Kataka, Nephrotoxicity
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13

Priyanka, Ramesh Chandra Tiwari, and Ved Bhushan Sharma. "Nirmali (Strychnos Potatorum linn.) A Precious Plant- A Review." AYUSHDHARA, January 15, 2023, 69–72. http://dx.doi.org/10.47070/ayushdhara.v9i6.1118.

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Ayurveda is one of the oldest health-care systems. The ancient Vedic literature contains scattered allusions to Ayurvedic remedies and other aspects of medicine and health. The vast majority of Atharvavedic knowledge is related to Ayurveda. One of Ayurveda's eight divisions, Agad Tantra, focuses on the identification of poisons, different poisons from the mineral, plant, and animal kingdoms, as well as artificial poisons made from toxic drugs and their treatment. Nirmali (Strychnos potatorum Linn) is one of a Vishagna (non-toxic) plant mentioned by Acharya Charak in 4th chapter of Sutrasthana in Charak samhita. Nirmali is a widely growing medium sized medicinal plant of Loganiaceae family. Seeds of Nirmali (Katak) have been used for the purification of water. This plant has contributed various pharmacological actions in the scientific field of Indian systems of medicine like Nirmali (Strychnos potatorum) seeds are alexipharmic, lithotriptic and cures strangury, head diseases etc., Roots of Nirmali cure leukoderma whereas fruits are useful in eye diseases, thirst, poisoning, and hallucinations. The fruits are emetic, diaphoretic, alexiteric etc. It contains a variety of phytochemical constituents such as a alkaloids, flavonoids, glycosides, lignins, phenols, saponins, sterols, and tannins. This review article of Nirmali (Katak) plant is going to provide brief information about its modern view.
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14

Sharmila, Chandiran, Rajendiran Selvam, and Sorimuthu Pillai Subramanian. "Evaluation of Bactericidal and Fungicidal Efficacy of Strychno spotatorum Linn. (Nirmali) Seeds." Asian Journal of Research in Biochemistry, January 4, 2021, 1–10. http://dx.doi.org/10.9734/ajrb/2021/v8i130169.

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Aim: Diseases due to pathogenic microbes pose a great burden on human health and they have been correlated with socioeconomic, environmental, and ecological factors. The threat due to infectious diseases is further intensified by the continued emergence of new and multidrug resistant microorganisms. This scenario warrants a continuous search for antimicrobial agents preferably of plant origin due to their availability, accessibility, and affordability. The present study was aimed to evaluate the antibacterial and antifungal properties of Strychnos potatorum Linn (Nirmali) seeds using common pathogenic bacterial and fungal strains. Methodology: Fresh and matured S. potatorum seeds were used for the present study. The powdered seeds were delipidated with petroleum ether (60-80°C) overnight and the extract was filtered. Soxhalation was performed with 95% ethanol to extract the phyto-ingredients from the seeds. Four Gram positive, four Gram negative, and eight fungal strains were used. The antimicrobial activity was evaluated by disc diffusion and well diffusion methods. The Minimum inhibitory concentration (MIC) Minimum bactericidal concentrations (MBC), Minimum fungicidal concentration (MFC) were assayed. Results: The data obtained through the disc diffusion, well diffusion, the minimum bactericidal concentration, and minimum fungicidal concentrations revealed that the ethanolic extract of the seeds possesses significant antibacterial and antifungal activities. The results obtained were compared with standard drugs widely prescribed for antimicrobial therapy. Conclusion: The present study provides the scientific rationale for the use of Strychnos potatorum seeds in traditional medicine and a rich source of phytochemicals having significant antimicrobial activities.
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15

Sharmila, Chandiran, Rajendiran Selvam, and Sorimuthu Pillai Subramanian. "Evaluation of Bactericidal and Fungicidal Efficacy of Strychno spotatorum Linn. (Nirmali) Seeds." Asian Journal of Research in Biochemistry, January 4, 2021, 1–10. http://dx.doi.org/10.9734/ajrb/2021/v8i130169.

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Aim: Diseases due to pathogenic microbes pose a great burden on human health and they have been correlated with socioeconomic, environmental, and ecological factors. The threat due to infectious diseases is further intensified by the continued emergence of new and multidrug resistant microorganisms. This scenario warrants a continuous search for antimicrobial agents preferably of plant origin due to their availability, accessibility, and affordability. The present study was aimed to evaluate the antibacterial and antifungal properties of Strychnos potatorum Linn (Nirmali) seeds using common pathogenic bacterial and fungal strains. Methodology: Fresh and matured S. potatorum seeds were used for the present study. The powdered seeds were delipidated with petroleum ether (60-80°C) overnight and the extract was filtered. Soxhalation was performed with 95% ethanol to extract the phyto-ingredients from the seeds. Four Gram positive, four Gram negative, and eight fungal strains were used. The antimicrobial activity was evaluated by disc diffusion and well diffusion methods. The Minimum inhibitory concentration (MIC) Minimum bactericidal concentrations (MBC), Minimum fungicidal concentration (MFC) were assayed. Results: The data obtained through the disc diffusion, well diffusion, the minimum bactericidal concentration, and minimum fungicidal concentrations revealed that the ethanolic extract of the seeds possesses significant antibacterial and antifungal activities. The results obtained were compared with standard drugs widely prescribed for antimicrobial therapy. Conclusion: The present study provides the scientific rationale for the use of Strychnos potatorum seeds in traditional medicine and a rich source of phytochemicals having significant antimicrobial activities.
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16

Kantipudi, Shrika, and Leya Joykutty. "Finding an eco-friendly and effective flocculation method to remove algal blooms from water." Journal of Student Research 12, no. 2 (May 31, 2023). http://dx.doi.org/10.47611/jsrhs.v12i2.4428.

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Algal blooms are rapid growth of microscopic algae in the water that are harmful to the environment because they block sunlight from reaching plants under the surface, deplete the water of useful nutrients, and release carbon emissions. Flocculation is a method that is used to remove algae and it works by binding and agglomerating suspended particles in water to form large particles to assist in their settling. However, most flocculants are chemical flocculants and may harm water quality. Bio-flocculation based on natural flocculants has been studied in drinking water treatment plants (DWTPs) as an eco-friendly alternative technology to conventional flocculants for both turbidity and HABs removal. The total solids assay, sedimentation kinetics assay, and pH testing will be used to measure the effectiveness of flocculants and water quality. These assays were tested with three types of algae: Chlorella vulgaris, Spirulina, Scenedesmus obliquus, and five types of flocculants: Aluminium Sulfate, Copper Sulfate, Chitosan, Moringa oleifera, and Strychnos potatorum Linn. The data collected so far in the study show that the chemical flocculants and bio-flocculants have a similar effectivity at flocculating algae from the water. The findings suggest that there is no significant difference between the bio-flocculants and the chemical flocculant. and that all of the flocculants will be effective. pH testing results have shown that Chitosan, Moringa oleifera, and Strychnos potatorum Linn affect the water quality the least which makes them the more environmentally friendly flocculants.
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17

Aurlina, R., R. R. Gopi, Thaninayagam Ebenezer, H. Joy Prabu, and I. Johnson. "Antibacterial study of silver nanoparticles synthesized using Strychnos potatorum(linn) – Green synthesis method." Materials Today: Proceedings, July 2022. http://dx.doi.org/10.1016/j.matpr.2022.07.118.

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18

Neelamkavil, Sandhya Vincent, and John E. Thoppil. "Genotoxic assessment of calcium hypochlorite and Strychnos potatorum Linn. seeds—two commonly used water purifying agents." Reviews on Environmental Health, January 20, 2014. http://dx.doi.org/10.1515/reveh-2014-0066.

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19

Ekambaram, Sanmugapriya, Senthamil Selvan Perumal, and Venkataraman Subramanian. "Evaluation of antiarthritic activity of Strychnos potatorum Linn seeds in Freund's adjuvant induced arthritic rat model." BMC Complementary and Alternative Medicine 10, no. 1 (October 13, 2010). http://dx.doi.org/10.1186/1472-6882-10-56.

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20

Wee, Wei Wen, Mei Yuen Siau, Senthil Kumar Arumugasamy, and Kirupa Sankar Muthuvelu. "Modelling of adsorption of anionic azo dye using Strychnos potatorum Linn seeds (SPS) from aqueous solution with artificial neural network (ANN)." Environmental Monitoring and Assessment 193, no. 10 (September 9, 2021). http://dx.doi.org/10.1007/s10661-021-09412-4.

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21

Nimbekar, Tulsidas, Ashish Jain, and Pradeep Kumar Mohanty. "Phytochemical screening and In-Vitro Antidiabetic Activity of Extracts of some Indian Medicinal Plants." Research Journal of Pharmacy and Technology, April 29, 2021, 2026–30. http://dx.doi.org/10.52711/0974-360x.2021.00359.

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The present scientific investigation deals with the extraction of some Indian medicinal plants include, Manilkara hexandra Roxb. stem bark (Sapotaceae), Strychnous potatorum Linn. dried seeds (Loganiaceae), Salacia reticulata Wight. stem bark (Celastraceae) and identification of chemical constituents by using preliminary phytochemical tests. The extracts were screened for their potential in-vitro anti-diabetic studies so as to ensure the biological potency of the plant. The study also includes qualitative screening of the phytonutrients, Free radical scavenging activity by DPPH assay method and assessment of total antioxidant activity by phosphor-molybdate assay method were evaluated. From the study we revealed that the all plants contain various classes of secondary metabolites and also possess a moderate anti-diabetic activity it terms of alpha amylase inhibition.
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