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1

Harmandayan, Rita. Transformation of Streptococcus mutans by electroporation. [Toronto: Faculty of Dentistry, University of Toronto], 1990.

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2

Shigeyuki, Hamada, ed. Molecular microbiology and immunobiology of Streptococcus Mutans ; proceedings of an International Conference on "Cellular, Molecular, and Clinical Aspects of Streptococcus Mutans" held in Birmingham, Alabama, USA, on September 18-20, 1985. Amsterdam: Elsevier Science Publishers, 1986.

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3

Hanna, Michael N. Molecular mechanisms involved in the acid tolerance response of Streptococcus mutans. Ottawa: National Library of Canada, 2001.

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4

Twetman, Svante. Antibacterial effects of human salivary lysozyme with special reference to Streptococcus mutans. Stockholm: Departments of Pedodontics and Oral Microbiology, Karolinska Institutet, 1985.

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5

Branting, Christina. Studies on S øt ør øe øp øt øo øc øo øc øc øu øs ø m øu øt øa øn øs ø glucans with special reference to cell adhesion. Stockholm: Kongl. Carolinska Medico Chirurgiska Institutet, 1988.

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6

Zarrabian, Shirin. Development of improved slow-release dental varnish formulations effective against streptococcus mutans in vitro. [Toronto: Faculty of Dentistry, University of Toronto], 1992.

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7

Zarrabian, Shirin. Development of improved slow-release dental varnish formulations effective against Streptococcus mutans in vitro. Ottawa: National Library of Canada, 1994.

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8

Wang, Dongsheng. Molecular cloning and nucleotide sequence of a Streptococcus mutans gene encoding biotin carboxyl carrier protein. Ottawa: National Library of Canada = Bibliothèque nationale du Canada, 1993.

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9

Wang, Dongsheng. Molecular cloning and nucleotide sequence of a streptococcus mutans gene encoding biotin carboxyl carrier protein. [Toronto: Faculty of Dentistry, University of Toronto], 1992.

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10

Newsholme, Heather Dawn Bickell. Influence of a substituted guar gum on the adshesion of streptococcus mutans to glass and hydroxylapatite. Salford: University of Salford, 1985.

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11

Senadheera, M. Dilani. The VicR/K signal transduction system in Streptococcus mutans. 2007, 2007.

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12

Lee, Janet. Identification of competence genes in streptococcus mutans by functional genomic analysis. 2001.

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13

Lackovic, Kresimir P. Involvement of an amino acid transporter in the acid tolerance of streptococcus mutans. 2003, 2003.

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14

Balanyk, Thomas Elie. Development of sustained-release antimicrobial dental varnishes effective against "Streptococcus mutans in vitro". 1986.

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15

Padilla, Luis, Kamyre Neyra, Vladimir Huacasi, and Sonia Macedo. Efecto antibacterial in vitro del extracto etanolico de Hibiscus sabdariffa L. sobre cepas de Streptococcus mutans. Instituto Universitario de Innovación Ciencia y Tecnología Inudi Perú, 2022. http://dx.doi.org/10.35622/inudi.b.012.

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Abstract:
La caries dental es una de las enfermedades más frecuentes a nivel mundial y debido a su prevalecía se comenzó a utilizar la fitoterapia como tratamiento alternativo, la Hibiscus sabdariffa L. posee gran variedad de propiedades terapéuticas de las cuales en este estudio destaca su actividad antibacterial. Objetivo: El objetivo de esta investigación fue determinar el efecto antibacterial in vitro del extracto etanólico de Hibiscus sabdariffa L. sobre cepas de Streptococcus mutans a las 24 y 48 horas. Materiales y métodos: La investigación fue aplicativa de diseño experimental y medición prospectiva. La muestra fue obtenida de pacientes que firmaron el consentimiento informado para así poder obtener las cepas de Streptococcus mutans. Se cultivaron en 16 placas Petri y en cada placa se distribuyeron 7 discos de papel filtro N°4, la técnica fue de difusión por disco de Kirby Bauer con pozos, con un total de 112 discos y pozos; las placas Petri se dividieron en 4 grupos de acuerdo a las concentraciones del extracto etanólico de Hibiscus sabdariffa L. que se obtuvo por maceración con alcohol al 96% para obtener una muestra al 100% extracto etanólico de Hibiscus sabdariffa L. y para obtener las concentraciones de 25%, 50% y 75% se utilizó alcohol para realizar las diluciones. Se consideró la clorhexidina al 0.12% como control positivo y al agua destilada como control negativo. Resultados: Sé demostró que la Hibiscus sabdariffa L. tiene efecto inhibitorio. El mejor efecto se registró a las 48 horas al 100% de concentración. Obteniendo un halo de inhibición de 14.23mm. Conclusión: El extracto etanólico de la Hibiscus sabdariffa L. sí tiene efecto antibacterial in vitro sobre las cepas de Streptococcus mutans.
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16

Munro, Cindy Louise. SUCROSE-DERIVED EXOPOLYSACCHARIDES OF STREPTOCOCCUS MUTANS ARE VIRULENCE FACTORS IN DENTAL CARIES AND ENDOCARDITIS. 1992.

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17

Huang, Yi-Chen Cathy. Peptide analogues of the Streptococcus mutans competence stimulating peptide (CSP) as inhibitors of quorum sensing. 2005.

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18

Huang, Yi-Chen Cathy. Peptide analogues of the streptococcus mutans competence stimulating peptide (CSP) as inhibitors of quorum sensing. 2005, 2005.

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