Academic literature on the topic 'Stratum corneum swelling'

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Journal articles on the topic "Stratum corneum swelling"

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Malnati, Claudio, Daniel Fehr, Fabrizio Spano, and Mathias Bonmarin. "Modeling Stratum Corneum Swelling for the Optimization of Electrode-Based Skin Hydration Sensors." Sensors 21, no. 12 (June 9, 2021): 3986. http://dx.doi.org/10.3390/s21123986.

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We present a novel computational model of the human skin designed to investigate dielectric spectroscopy electrodes for stratum corneum hydration monitoring. The multilayer skin model allows for the swelling of the stratum corneum, as well as the variations of the dielectric properties under several hydration levels. According to the results, the stratum corneum thickness variations should not be neglected. For high hydration levels, swelling reduces the skin capacitance in comparison to a fixed stratum corneum thickness model. In addition, different fringing-field electrodes are evaluated in terms of sensitivity to the stratum corneum hydration level. As expected, both conductance and capacitance types of electrodes are influenced by the electrode geometry and dimension. However, the sensitivity of the conductance electrodes is more affected by dimension changes than the capacitance electrode leading to potential design optimization.
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Norlén, L., Axel Emilson, and Bo Forslind. "Stratum corneum swelling. Biophysical and computer assisted quantitative assessments." Archives of Dermatological Research 289, no. 9 (September 12, 1997): 506–13. http://dx.doi.org/10.1007/s004030050231.

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Li, Xin, Robert Johnson, Ben Weinstein, Elizabeth Wilder, Ed Smith, and Gerald B. Kasting. "Dynamics of water transport and swelling in human stratum corneum." Chemical Engineering Science 138 (December 2015): 164–72. http://dx.doi.org/10.1016/j.ces.2015.08.009.

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Olmsted, Peter, Chinmay Das, and Massimo Noro. "Cholesterol Flip-Flop and Lack of Swelling in Stratum Corneum Lipid Bilayers." Biophysical Journal 108, no. 2 (January 2015): 413a. http://dx.doi.org/10.1016/j.bpj.2014.11.2264.

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Ohta, N., I. Hatta, S. Ban, H. Tanaka, and S. Nakata. "Swelling of lipid lamellae with short repeat distance in hairless mouse stratum corneum." Seibutsu Butsuri 41, supplement (2001): S133. http://dx.doi.org/10.2142/biophys.41.s133_1.

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박승환 and 하병조. "Study on Swelling and Rheological Properties of the Stratum Corneum under Various Moisturizers and pH Conditions." Journal of Investigative Cosmetology 6, no. 4 (December 2010): 401–6. http://dx.doi.org/10.15810/jic.2010.6.4.011.

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Pashkovski, Eugene, Efrem Braun, Daeyeon Lee, and David Weitz. "Permeability of Model Stratum Corneum Lipid Membrane Measured using Quartz Crystal Microbalance: Non-Fickian Diffusion and Transient Membrane Swelling." Biophysical Journal 98, no. 3 (January 2010): 481a. http://dx.doi.org/10.1016/j.bpj.2009.12.2618.

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Terzopoulou, Zoi, Anna Michopoulou, Artemis Palamidi, Elena Koliakou, and Dimitrios Bikiaris. "Preparation and Evaluation of Collagen-Based Patches as Curcumin Carriers." Polymers 12, no. 10 (October 17, 2020): 2393. http://dx.doi.org/10.3390/polym12102393.

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Patients with psoriasis are dissatisfied with the standard pharmacological treatments, whether systemic or topical, with many of them showing interest in complementary and alternative medicine. Curcumin (Cur), a natural polyphenol derived from turmeric, has recently gained attention for skin-related diseases because of its proven anti-inflammatory action. However, topical treatment with Cur would be inadequate because of its hydrophobicity, instability, and low bioavailability. In addition, hyperkeratosis and lack of moisture in psoriatic skin result in low penetration that would prevent actives from permeating the stratum corneum. In this work, a polymer-based formulation of Cur for the topical treatment of psoriasis is reported. To improve the physicochemical stability of Cur, it was first encapsulated in chitosan nanoparticles. The Cur-loaded nanoparticles were incorporated in a hydrophilic, biocompatible collagen-based patch. The nanoparticle-containing porous collagen patches were then chemically cross-linked. Morphology, chemical interactions, swelling ratio, enzymatic hydrolysis, and Cur release from the patches were evaluated. All patches showed excellent swelling ratio, up to ~1500%, and after cross-linking, the pore size decreased, and their hydrolysis rates decelerated. The in vitro release of Cur was sustained with an initial burst release, reaching 55% after 24 h. Cur within the scaffolds imparted a proliferation inhibitory effect on psoriatic human keratinocytes in vitro.
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Ohta, Noboru, Sadanori Ban, Hiroshi Tanaka, Satoru Nakata, and Ichiro Hatta. "Swelling of intercellular lipid lamellar structure with short repeat distance in hairless mouse stratum corneum as studied by X-ray diffraction." Chemistry and Physics of Lipids 123, no. 1 (March 2003): 1–8. http://dx.doi.org/10.1016/s0009-3084(02)00126-3.

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Eckert, Ralph W., Sabrina Wiemann, and Cornelia M. Keck. "Improved Dermal and Transdermal Delivery of Curcumin with SmartFilms and Nanocrystals." Molecules 26, no. 6 (March 15, 2021): 1633. http://dx.doi.org/10.3390/molecules26061633.

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Poor aqueous solubility of active compounds is a major issue in today’s drug delivery. In this study the smartFilm-technology was exploited to improve the dermal penetration efficacy of a poorly soluble active compound (curcumin). Results were compared to the dermal penetration efficacy of curcumin from curcumin bulk suspensions and nanocrystals, respectively. The smartFilms enabled an effective dermal and transdermal penetration of curcumin, whereas curcumin bulk- and nanosuspensions were less efficient when the curcumin content was similar to the curcumin content in the smartFilms. Interestingly, it was found that increasing numbers of curcumin particles within the suspensions increased the passive dermal penetration of curcumin. The effect is caused by an aqueous meniscus that is created between particle and skin if the dispersion medium evaporates. The connecting liquid meniscus causes a local swelling of the stratum corneum and maintains a high local concentration gradient between drug particles and skin. Thus, leading to a high local passive dermal penetration of curcumin. The findings suggest a new dermal penetration mechanism for active compounds from nano-particulate drug delivery systems, which can be the base for the development of topical drug products with improved penetration efficacy in the future.
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Dissertations / Theses on the topic "Stratum corneum swelling"

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Evans, Myfanwy Ella. "Three-dimensional entanglement: knots, knits and nets." Phd thesis, 2011. http://hdl.handle.net/1885/9502.

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Three-dimensional entanglement, including knots, periodic arrays of woven filaments (weavings) and periodic arrays of interpenetrating networks (nets), forms an integral part of the analysis of structure within the natural sciences. This thesis constructs a catalogue of 3-periodic entanglements via a scaffold of Triply-Periodic Minimal Surfaces (TPMS). The two-dimensional Hyperbolic plane can be wrapped over a TPMS in much the same way as the two-dimensional Euclidean plane can be wrapped over a cylinder. Thus vertices and edges of free tilings of the Hyperbolic plane, which are tilings by tiles of infinite size, can be wrapped over a TPMS to represent vertices and edges of an array in three-dimensional Euclidean space. In doing this, we harness the simplicity of a two-dimensional surface as compared with 3D space to build our catalogue. We numerically tighten these entangled flexible knits and nets to an ideal conformation that minimises the ratio of edge (or filament) length to diameter. To enable the tightening of periodic entanglements which may contain vertices, we extend the Shrink-On-No-Overlaps algorithm, a simple and fast algorithm for tightening finite knots and links. The ideal geometry of 3-periodic weavings found through the tightening process exposes an interesting physical property: Dilatancy. The cooperative straightening of the filaments with a fixed diameter induces an expansion of the material accompanied with an increase in the free volume of the material. Further, we predict a dilatant rod packing as the structure of the keratin matrix in the corneocytes of mammalian skin, where the dilatant property of the matrix allows the skin to maintain structural integrity while experiencing a large expansion during the uptake of water.
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