Journal articles: 'Strain longitudinale globale'

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Galderisi, Maurizio, and Bruno Trimarco. "Global longitudinal strain." Journal of Hypertension 34, no. 6 (June 2016): 1050–51. http://dx.doi.org/10.1097/hjh.0000000000000920.

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Haugaa, Kristina H., and Lars A. Dejgaard. "Global Longitudinal Strain." Journal of the American College of Cardiology 71, no. 18 (May 2018): 1958–59. http://dx.doi.org/10.1016/j.jacc.2018.03.015.

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Reiber, Johan H. C. "Global longitudinal strain (GLS)." International Journal of Cardiovascular Imaging 38, no. 2 (February 2022): 269–70. http://dx.doi.org/10.1007/s10554-022-02556-5.

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Kwong, Raymond Y., Christopher M. Kramer, and Y. Chandrashekhar. "CMR Global Longitudinal Strain." JACC: Cardiovascular Imaging 11, no. 10 (October 2018): 1554–55. http://dx.doi.org/10.1016/j.jcmg.2018.09.002.

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D’Elia, Nicholas, Stefano Caselli, Wojciech Kosmala, Patrizio Lancellotti, Daniel Morris, Denisa Muraru, Masaaki Takeuchi, et al. "Normal Global Longitudinal Strain." JACC: Cardiovascular Imaging 13, no. 1 (January 2020): 167–69. http://dx.doi.org/10.1016/j.jcmg.2019.07.020.

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Reddy, Abhinay, Vasvi Singh, Badri Karthikeyan, Leyi Jiang, Silva Kristo, Sharma Kattel, Ram Amuthan, Saraswati Pokharel, and Umesh C. Sharma. "Biventricular Strain Imaging with Cardiac MRI in Genotyped and Histology Validated Amyloid Cardiomyopathy." Cardiogenetics 11, no. 3 (June 30, 2021): 98–110. http://dx.doi.org/10.3390/cardiogenetics11030011.

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Cardiac amyloidosis (CA) is a common and potentially fatal infiltrative cardiomyopathy. Contrast-enhanced cardiac MRI (CMR) is used as a diagnostic tool. However, utility of CMR for the comprehensive analysis of biventricular strains and strain rates is not reported as extensively as echocardiography. In addition, RV strain analysis using CMR has not been described previously. Objectives: We sought to study the global and regional indices of biventricular strain and strain rates in endomyocardial biopsy (EMB)-proven, genotyped cases of CA. Methods: A database of 80 EMBs was curated from 2012 to 2019 based on histology. A total of 19 EMBs positive for CA were subjected to further tissue-characterization with histology, and compared with four normal biopsy specimens. Samples were genotyped for ATTR- or AL-subtypes. Five patients, with both echocardiography and contrast-enhanced CMR performed 72-h apart, were subjected to comprehensive analysis of biventricular strain and strain-rates. Results: Histology confirmed that the selected samples were indeed positive for cardiac amyloid. Echocardiography showed reduced global and regional left-ventricular (LV) longitudinal strain indices. CMR with tissue-characterization of LV showed global reductions in circumferential, radial and longitudinal strains and strain-rates, following a general trend with the echocardiographic findings. The basal right-ventricular (RV) segments had reduced circumferential strains with no changes in longitudinal strain. Conclusions: In addition to providing a clinical diagnosis of CA based on contrast clearance-dynamics, CMR can be a potent tool for accurate functional assessment of global and regional changes in strain and strain-rates involving both LV and RV. Further studies are warranted to validate and curate the strain imaging capacity of CMR in CA.

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Yeong, C., and W. Wang. "Is Manually Measured Global Longitudinal Strain a Reliable Alternative to Speckle Tracking Global Longitudinal Strain?" Heart, Lung and Circulation 31 (2022): S166. http://dx.doi.org/10.1016/j.hlc.2022.06.261.

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Chernykh, Nadezhda, Alla Tarasova, and Olga Groznova. "2D speckle-tracking in assessment of myocardial strain in children with hypertrophic cardiomyopathy." Acta Medico-Biotechnica 14, no. 2 (June 12, 2022): 10–17. http://dx.doi.org/10.18690/actabiomed.219.

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Purpose: To assess the myocardial strain in children with hypertrophic cardiomyopathy (HCM). Methods: A total of 61 patients aged between 7 and 17 years with an asymmetric form of HCM underwent an ultrasound examination of the heart using standard techniques. An assessment of the left ventricular systolic function was performed using the two-dimensional (2D) speckle-tracking mode with analysis parameters that included global and segmental longitudinal, circumferential, and radial myocardial strains. Strain data for the subendocardial and subepicardial layers for each segment of the left ventricle, as well as their total values, were determined. Results: Global longitudinal strain and longitudinal strain rate were dec reased due to the impaired contractility of hypertrophied myocardial segments in 100% of cases of non-obstructive and obstructive HCM forms. A decrease in global, radial, and circumferential strain parameters and their rates has been observed in all children with an obstructive form of HCM and 39 (86.6%) patients with non-obstructive form. At the same time, there was a statistically significant difference between strains and strain rates in children with a non-obstructive form of HCM in comparison to those with an obstructive form of the disease. Conclusion: Changes in myocardial strains observed using the 2D speckle-tracking mode in children with HCM indicate early systolic dysfunction of the left ventricle. Longitudinal strain was the most sensitive compared to radial and circumferential types. It was statistically significantly different in children with an obstructive form of HCM compared to those with non-obstructive form of the disease. These results are important for early therapy initiation and, therefore, may improve prognosis in children with HCM.

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Støylen, Asbjørn, Harald Edvard Mølmen, and Håvard Dalen. "Left ventricular global strains by linear measurements in three dimensions: interrelations and relations to age, gender and body size in the HUNT Study." Open Heart 6, no. 2 (September 2019): e001050. http://dx.doi.org/10.1136/openhrt-2019-001050.

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BackgroundStrain is a relative deformation and has three dimensions, in the left ventricle (LV) usually longitudinal (εL), transmural (εT) and circumferential (εC) strain. All three components can be measured generically by the basic systolic and diastolic dimension measures of LV wall length, wall thickness and diameter. In this observational study we aimed to study the relations of normal generic strains to age, body size and gender, as well as the interrelations between the three strain components.MethodsGeneric strains derived from dimension measures by longitudinal and cross-sectional M-mode in all three dimensions were measured in 1266 individuals without heart disease from the Nord-Trøndelag Health Study.ResultsThe mean εL was −16.3%, εC was −22.7% and εT was 56.5%. Normal values by age and gender are provided. There was a gradient of εC from the endocardial, via the midwall to the external level, lowest at the external. All strains decreased in absolute values by increasing body surface area (BSA) and age, relations were strongest for εL. Gender differences were mainly a function of BSA differences. The three strain components were strongly interrelated through myocardial incompressibility.ConclusionsGlobal systolic strain is the total deformation of the myocardium; the three strain components are the spatial coordinates of this deformation, irrespective of the technology used for measurement. Normal values are method-dependent and not normative across methods. Interrelation of strains indicates a high degree of myocardial incompressibility and that longitudinal strain carries most of the total information.

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Moslehi, Javid J., and Ronald M. Witteles. "Global Longitudinal Strain in Cardio-Oncology." Journal of the American College of Cardiology 77, no. 4 (February 2021): 402–4. http://dx.doi.org/10.1016/j.jacc.2020.12.014.

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Vijayaraghavan, Govindan, and Sivasubramonian Sivasankaran. "Global longitudinal strain: A practical step-by-step approach to longitudinal strain imaging." Journal of The Indian Academy of Echocardiography & Cardiovascular Imaging 4, no. 1 (2020): 22. http://dx.doi.org/10.4103/jiae.jiae_16_19.

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Li, Hao, Yangyang Qu, Patrick Metze, Florian Sommerfeld, Steffen Just, Alireza Abaei, and Volker Rasche. "Quantification of Biventricular Myocardial Strain Using CMR Feature Tracking: Reproducibility in Small Animals." BioMed Research International 2021 (January 22, 2021): 1–14. http://dx.doi.org/10.1155/2021/8492705.

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Myocardial strain is a well-validated parameter for evaluating myocardial contraction. Cardiovascular magnetic resonance myocardial feature tracking (CMR-FT) is a novel method for the quantitative measurements of myocardial strain from routine cine acquisitions. In this study, we investigated the influence of temporal resolution on tracking accuracy of CMR-FT and the intraobserver, interobserver, and interstudy reproducibilities for biventricular strain analysis in mice from self-gated CMR at 11.7 T. 12 constitutive nexilin knockout (Nexn-KO) mice, heterozygous (Het, N = 6 ) and wild-type (WT, N = 6 ), were measured with a well-established self-gating sequence twice within two weeks. CMR-FT measures of biventricular global and segmental strain parameters were derived. Interstudy, intraobserver, and interobserver reproducibilities were investigated. For the assessment of the impact of the temporal resolution for the outcome in CMR-FT, highly oversampled semi-4 chamber and midventricular short-axis data were acquired and reconstructed with 10 to 80 phases per cardiac cycle. A generally reduced biventricular myocardial strain was observed in Nexn-KO Het mice. Excellent intraobserver and interobserver reproducibility was achieved in all global strains (ICC range from 0.76 to 0.99), where global right ventricle circumferential strain (RCSSAX) showed an only good interobserver reproducibility (ICC 0.65, 0.11-0.89). For interstudy reproducibility, left ventricle longitudinal strain (LLSLAX) was the most reproducible measure of strain (ICC 0.90, 0.71-0.97). The left ventricle radial strain (LRSSAX) (ICC 0.50, 0.10-0.83) showed fair reproducibility and RCSSAX (ICC 0.36, 0.14-0.74) showed only poor reproducibility. In general, compared with global strains, the segmental strains showed relatively lower reproducibility. A minimal temporal resolution of 20 phases per cardiac cycle appeared sufficient for CMR-FT strain analysis. The analysis of myocardial strain from high-resolution self-gated cine images by CMR-FT provides a highly reproducible method for assessing myocardial contraction in small rodent animals. Especially, global LV longitudinal and circumferential strain revealed excellent reproducibility of intra- and interobserver and interstudy measurements.

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Gozar, Liliana, Mihaela Iancu, Horea Gozar, Anca Sglimbea, Andreea Cerghit Paler, Dorottya Gabor-Miklosi, Rodica Toganel, Amalia Făgărășan, Diana Ramona Iurian, and Daniela Toma. "Assessment of Biventricular Myocardial Function with 2-Dimensional Strain and Conventional Echocardiographic Parameters: A Comparative Analysis in Healthy Infants and Patients with Severe and Critical Pulmonary Stenosis." Journal of Personalized Medicine 12, no. 1 (January 6, 2022): 57. http://dx.doi.org/10.3390/jpm12010057.

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Our aim was to compare the global longitudinal and regional biventricular strain between infants with severe and critical pulmonary stenosis (PS), and controls; to compare pre- and post-procedural strain values in infants with severe and critical PS; and to assess the correlations between echocardiographic strain and conventional parameters. We conducted a retrospective single-center study. The comparisons of echocardiographic variables were performed using separate linear mixed models. The overall mean right ventricle (RV) regional strains measured before intervention in PS patients was significantly different when compared to the control group (p = 0.0324). We found a significant change in the left ventricle, RV, and inter-ventricular septum strain (IVS) values from basal to apical location (p < 0.05). IVS strain values showed a higher decrease in mean strain values from basal to apical in PS patients. There was no significant difference in means of baseline and post-interventional strain values in PS patients (p > 0.05). Following the strain analysis in patients with PS, we obtained statistically significant changes in the RV global-4-chamber longitudinal strain (RV4C). The RV4C, which quantifies the longitudinal strain to the entire RV, can be used in current clinical practice for the evaluation of RV function in infants with severe and critical PS. The longitudinal and segmental strain capture the pathological changes in the IVS, modifications that cannot be highlighted through a classical echocardiographic evaluation.

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Zhang, Hong-wei, Jun Gu, Zheng-hua Xiao, Ya-jiao Li, Peng Yang, Yao Huang, Chen Lu, Er-yong Zhang, and Jia Hu. "Global longitudinal strain in prosthesis-patient mismatch." Journal of Cardiovascular Medicine 20, no. 7 (July 2019): 434–41. http://dx.doi.org/10.2459/jcm.0000000000000819.

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King, A., J. Thambyrajah, E. Leng, and M. J. Stewart. "Global longitudinal strain: a useful everyday measurement?" Echo Research and Practice 3, no. 3 (September 2016): 85–93. http://dx.doi.org/10.1530/erp-16-0022.

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Cosyns, Bernard, and Mani A. Vannan. "Global longitudinal strain in severe aortic stenosis." European Heart Journal - Cardiovascular Imaging 21, no. 11 (October 6, 2020): 1259–61. http://dx.doi.org/10.1093/ehjci/jeaa260.

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Szilveszter, Bálint, Anikó Ilona Nagy, Borbála Vattay, Márton Kolossváry, Andrea Bartykowszki, Attila Tóth, Ferenc Suhai, Astrid Apor, Béla Merkely, and Pál Maurovich-Horvat. "Ct Based Assessment Of Global Longitudinal Strain." Journal of Cardiovascular Computed Tomography 13, no. 1 (January 2019): S49. http://dx.doi.org/10.1016/j.jcct.2018.12.051.

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Zhang, Shiwen, Yufei Zhou, Shuguang Han, Yanfang Ma, Cheng Wang, and Yinglong Hou. "The Diagnostic and Prognostic Value of Cardiac Magnetic Resonance Strain Analysis in Heart Failure with Preserved Ejection Fraction." Contrast Media & Molecular Imaging 2023 (February 6, 2023): 1–8. http://dx.doi.org/10.1155/2023/5996741.

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Background. Strain analysis of cardiac magnetic resonance (CMR) is critical for the diagnosis and prognosis of heart failure (HF) with preserved ejection fraction (HFpEF). Our study aimed to identify the diagnostic and prognostic value of strain analysis revealed by CMR in HFpEF. Methods. Participants in HFpEF and control were recruited according to the guideline. Baseline information, clinical parameters, blood samples were collected, and echocardiography and CMR examination were performed. Various parameters, including global longitudinal strain, global circumferential strain (GCS) and global radial strain in left ventricle (LV), right ventricle (RV), and left atrium, were measured from CMR. Receiver operator curve (ROC) was established to evaluate the diagnostic and prognostic value of strains in HFpEF. Results. Seven strains, with the exception of RVGCS, were employed to generate ROC curves after t-test. All strains had significant diagnostic value for HFpEF. The area under curve (AUC) of LV strains was greater than 0.7 and the AUC of the combined analysis of LV strains was 0.858 (95% confidence interval (CI): 0.798–0.919, sensitivity: 0.713, specificity: 0.875, P < 0.001 ), indicating that they had a higher diagnostic value than individual LV strains. However, individual strains had no predictive value in identifying end-point events in HFpEF, the AUC of coanalysis of LV strains was 0.722 (95% CI: 0.573–0.872, sensitivity: 0.500, specificity: 0.959, P = 0.004 ), indicating its prognostic relevance. Conclusion. Individual strain analysis in CMR may be useful for diagnosing HFpEF, the combination of LV strain analysis had the highest diagnostic value. Moreover, the prognostic value of individual strain analysis in predicting HFpEF outcome was not satisfactory while the combined usage of LV strain analysis was prognostically valuable in HFpEF outcome prediction.

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Sharifian, Maedeh, Nahid Rezaeian, Sanaz Asadian, Ali Mohammadzadeh, Ali Nahardani, Kianosh Kasani, Yaser Toloueitabar, Ali Mohammad Farahmand, and Leila Hosseini. "Efficacy of Novel Noncontrast Cardiac Magnetic Resonance Methods in Indicating Fibrosis in Hypertrophic Cardiomyopathy." Cardiology Research and Practice 2021 (May 24, 2021): 1–7. http://dx.doi.org/10.1155/2021/9931136.

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Objective. In hypertrophic cardiomyopathy (HCM), myocardial fibrosis is routinely shown by late gadolinium enhancement (LGE) in cardiac magnetic resonance (CMR) imaging. We evaluated the efficacy of 2 novel contrast-free CMR methods, namely, diffusion-weighted imaging (DWI) and feature-tracking (FT) method, in detecting myocardial fibrosis. Methods. This cross-sectional study was conducted on 26 patients with HCM. Visual and quantitative comparisons were made between DWI and LGE images. Regional longitudinal, circumferential, and radial strains were compared between LGE-positive and LGE-negative segments. Moreover, global strains were compared between LGE-positive and LGE-negative patients as well as between patients with mild and marked LGE. Results. All 3 strains showed significant differences between LGE-positive and LGE-negative segments ( P < 0.001 ). The regional longitudinal and circumferential strain parameters showed significant associations with LGE ( P < 0.001 ), while regional circumferential strain was the only independent predictor of LGE in logistic regression models (OR: 1.140, 95% CI: 1.073 to 1.207, P < 0.001 ). A comparison of global strains between patients with LGE percentages of below 15% and above 15% demonstrated that global circumferential strain was the only parameter to show impairment in the group with marked myocardial fibrosis, with borderline significance ( P = 0.09 ). A review of 212 segments demonstrated a qualitative visual agreement between DWI and LGE in 193 segments (91%). The mean apparent diffusion coefficient was comparable between LGE-positive and LGE-negative segments ( P = 0.51 ). Conclusions. FT-CMR, especially regional circumferential strain, can reliably show fibrosis-containing segments in HCM. Further, DWI can function as an efficient qualitative method for the estimation of the fibrosis extent in HCM.

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Negishi, Tomoko, and Kazuaki Negishi. "How to standardize measurement of global longitudinal strain." Journal of Medical Ultrasonics 49, no. 1 (November 17, 2021): 45–52. http://dx.doi.org/10.1007/s10396-021-01160-9.

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Szymanski, Catherine, Franck Lévy, and Christophe Tribouilloy. "Should LVEF be replaced by global longitudinal strain?" Heart 100, no. 21 (July 21, 2014): 1655–56. http://dx.doi.org/10.1136/heartjnl-2014-306186.

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Grapsa, Julia. "Left Ventricular Ejection Fraction and Global Longitudinal Strain." Journal of the American College of Cardiology 72, no. 9 (August 2018): 1065–66. http://dx.doi.org/10.1016/j.jacc.2018.05.070.

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Cavalcante, João L. "Global Longitudinal Strain in Asymptomatic Chronic Aortic Regurgitation." JACC: Cardiovascular Imaging 11, no. 5 (May 2018): 683–85. http://dx.doi.org/10.1016/j.jcmg.2017.04.004.

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Sławiński, Grzegorz, Maja Hawryszko, Aleksandra Liżewska-Springer, Izabela Nabiałek-Trojanowska, and Ewa Lewicka. "Global Longitudinal Strain in Cardio-Oncology: A Review." Cancers 15, no. 3 (February 3, 2023): 986. http://dx.doi.org/10.3390/cancers15030986.

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Several therapies used in cancer treatment are potentially cardiotoxic and may cause left ventricular (LV) dysfunction and heart failure. For decades, echocardiography has been the main modality for cardiac assessment in cancer patients, and the parameter examined in the context of cardiotoxicity was the left ventricular ejection fraction (LVEF). The assessment of the global longitudinal strain (GLS) using speckle tracking echocardiography (STE) is an emerging method for detecting and quantifying subtle disturbances in the global long-axis LV systolic function. In the latest ESC guidelines on cardio-oncology, GLS is an important element in diagnosing the cardiotoxicity of oncological therapy. A relative decrease in GLS of >15% during cancer treatment is the recommended cut-off point for suspecting subclinical cardiac dysfunction. An early diagnosis of asymptomatic cardiotoxicity allows the initiation of a cardioprotective treatment and reduces the risk of interruptions or changes in the oncological treatment in the event of LVEF deterioration, which may affect survival.

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Batta, Akash, Juniali Hatwal, and Yash Paul Sharma. "Global longitudinal strain in mild COVID-19 patients." Indian Heart Journal 74 (November 2022): S83. http://dx.doi.org/10.1016/j.ihj.2022.10.103.

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Khan, Umael, Tom R. Omdal, Knut Matre, and Gottfried Greve. "Speckle tracking derived strain in neonates: planes, layers and drift." International Journal of Cardiovascular Imaging 37, no. 7 (March 12, 2021): 2111–23. http://dx.doi.org/10.1007/s10554-021-02200-8.

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AbstractThe aims of this study was to assess the effect of using a four chamber versus a three plane model on speckle tracking derived global longitudinal strain, the effects of drift compensation, the effect of assessing strain in different layers and finally the interplay between these aspects for the assessment of strain in neonates. Speckle tracking derived longitudinal strain was obtained from 22 healthy neonates. ANOVA, Bland–Altman analyses, coefficients of variation and assessment of intraclass correlation coefficients were conducted to assess the effect of the abovementioned aspects as well as assess both inter-observer and intra-observer variability. Neither the use of the three plane model versus the four chamber model nor the use of drift compensation had a substantial effect on global longitudinal strain (less than 1%, depending on which layer was being assessed). A gradient was seen with increasing strain from the epicardial to endocardial layers, similar to what is seen in older subjects. Finally, drift compensation introduced more discrepancy in segmental strain values compared to global longitudinal strain. Global longitudinal strain in healthy neonates remains reasonably consistent regardless of whether the three plane or four chamber model is used and whether drift compensation is applied. Its value increases when one moves from the endocardial to the epicardial layer. Finally, drift compensation introduces more discrepancy for regional measures of longitudinal strain compared to global longitudinal strain.

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Paysal, Justine, Etienne Merlin, Emmanuelle Rochette, Daniel Terral, and Stéphane Nottin. "Global and Regional Myocardial Work in Female Adolescents with Weight Disorders." Journal of Clinical Medicine 10, no. 20 (October 12, 2021): 4671. http://dx.doi.org/10.3390/jcm10204671.

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Background: Anorexia nervosa (AN) and obesity (OB) lead to changes in SBP (i.e., loading conditions) that may affect left ventricular (LV) myocardial work (MW). The novel concept of LV pressure-strain loops allows non-invasive estimation of MW, this latter being correlated with cardiac energy metabolism. In addition, the study of regional MW can detect subtle alterations in cardiac function by highlighting an abnormal distribution of MW. Objective: The aim of this study was to assess the cardiac function of AN and OB patients by evaluating global and regional LV strains and MW. Methods: Eighty-seven female adolescents, comprising 26 with AN (14.6 ± 1.9 yrs. old), 28 with OB (13.2 ± 1.4 yrs. old), and 33 controls (14.0 ± 2.0 yrs. old) underwent speckle-tracking echography to assess global and regional LV strains and MW. Results: SBP was higher in adolescents with obesity than in AN patients or controls. Global MW was similar between groups. In AN patients and controls, longitudinal strains were higher at the apex than at the base of the LV, whereas they were similar in obesity patients, owing to a decrease in their apical longitudinal strain. Consequently, their MW was higher at the basal level than either of the other two groups (1854 ± 272 vs. 1501 ± 280 vs. 1575 ± 295 mmHg% in OB patients, AN patients, and controls, respectively. Conclusion: Despite altered SBP, the global MW of adolescents with weight disorders was unaffected. However, in adolescents with obesity, the distribution of their regional LV MW was altered, which might reflect specific regional remodeling.

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Guo, Abra, Colin McGuire, Peter Bergquist, Jose Vargas, and Monvadi Srichai-Parsia. "GLOBAL LONGITUDINAL STRAIN AND GLOBAL CIRCUMFERENTIAL STRAIN IN RELATION TO LATE GADOLINIUM ENHANCEMENT IN CMR." Journal of the American College of Cardiology 77, no. 18 (May 2021): 1396. http://dx.doi.org/10.1016/s0735-1097(21)02754-6.

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Du Toit, Riëtte, Phillip G. Herbst, Annari van Rensburg, Hendrik W. Snyman, Helmuth Reuter, and Anton F. Doubell. "Speckle tracking echocardiography in acute lupus myocarditis: comparison to conventional echocardiography." Echo Research and Practice 4, no. 2 (June 2017): 9–19. http://dx.doi.org/10.1530/erp-17-0005.

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Aims Lupus myocarditis occurs in 5–10% of patients with systemic lupus erythematosus (SLE). No single feature is diagnostic of lupus myocarditis. Speckle tracking echocardiography (STE) can detect subclinical left ventricular dysfunction in SLE patients, with limited research on its utility in clinical lupus myocarditis. We report on STE in comparison to conventional echocardiography in patients with clinical lupus myocarditis. Methods and results A retrospective study was done at a tertiary referral hospital in South Africa. SLE patients with lupus myocarditis were included and compared to healthy controls. Echocardiographic images were reanalyzed, including global longitudinal strain through STE. A poor echocardiographic outcome was defined as final left ventricular ejection fraction (LVEF) <40%. 28 SLE patients fulfilled the criteria. Global longitudinal strain correlated with global (LVEF: r = −0.808; P = 0.001) and regional (wall motion score: r = 0.715; P < 0.001) function. In patients presenting with a LVEF ≥50%, global longitudinal strain (P = 0.023), wall motion score (P = 0.005) and diastolic function (P = 0.004) were significantly impaired vs controls. Following treatment, LVEF (35–47% (P = 0.023)) and wall motion score (1.88–1.5 (P = 0.017)) improved but not global longitudinal strain. Initial LVEF (34%; P = 0.046) and global longitudinal strain (−9.5%; P = 0.095) were lower in patients with a final LVEF <40%. Conclusions This is the first known report on STE in a series of patients with clinical lupus myocarditis. Global longitudinal strain correlated with regional and global left ventricular function. Global longitudinal strain, wall motion score and diastolic parameters may be more sensitive markers of lupus myocarditis in patients presenting with a preserved LVEF ≥50%. A poor initial LVEF and global longitudinal strain were associated with a persistent LVEF <40%. Echocardiography is a non-invasive tool with diagnostic and prognostic value in lupus myocarditis.

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Espe, Emil K. S., Jan M. Aronsen, Einar S. Nordén, Lili Zhang, and Ivar Sjaastad. "Regional right ventricular function in rats: a novel magnetic resonance imaging method for measurement of right ventricular strain." American Journal of Physiology-Heart and Circulatory Physiology 318, no. 1 (January 1, 2020): H143—H153. http://dx.doi.org/10.1152/ajpheart.00357.2019.

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The function of the right ventricle (RV) is linked to clinical outcome in many cardiovascular diseases, but its role in experimental heart failure remains largely unexplored due to difficulties in measuring RV function in vivo. We aimed to advance RV imaging by establishing phase-contrast MRI (PC-MRI) as a robust method for measuring RV function in rodents. A total of 46 Wistar-Hannover rats with left ventricular (LV) myocardial infarction and 10 control rats (sham) were examined 6 wk after surgery. Using a 9.4-T preclinical MRI system, we utilized PC-MRI to measure strain/strain rate in the RV free wall under isoflurane anesthesia. Cine MRI was used to measure RV volumes. LV end-diastolic pressure (LVEDP) was measured and used to identify pulmonary congestion. The infarct rats were divided into two groups: those with signs of pulmonary congestion (PC), with LVEDP ≥ 15 mmHg ( n = 26) and those without signs of pulmonary congestion (NPC), with LVEDP < 15 mmHg ( n = 20). The NPC rats exhibited preserved RV strains/strain rates, whereas the PC rats exhibited reduced strains/strain rates (26–48% lower than sham). Of the strain parameters, longitudinal strain and strain rate exhibited the highest correlations to LVEDP and lung weight (rho = 0.65–0.72, P < 0.001). Basal longitudinal strain was most closely associated with signs of pulmonary congestion and indexes of RV remodeling. Longitudinal RV strain had higher area under the curve than ejection fraction for detecting subtle RV dysfunction (area under the curve = 0.85 vs. 0.67). In conclusion, we show for the first time that global and regional RV myocardial strain can be measured robustly in rodents. Reduced RV strain was closely associated with indexes of pulmonary congestion and molecular markers of RV remodeling. NEW & NOTEWORTHY Global and regional right ventricular myocardial strain can be measured with high reproducibility and low interobserver variability in rodents using tissue phase mapping MRI. Reduced right ventricular strain was associated with indexes of pulmonary congestion and molecular markers of right ventricular remodeling. Regional strain in the basal myocardium was considerably higher than in the apical myocardium.

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Choudhry, Muhammad W., Shujaur Rehman, Harvey Feigenbaum, and Stephen Sawada. "PROGNOSTIC UTILITY OF AFTERLOAD ADJUSTED GLOBAL LONGITUDINAL STRAIN AND BASAL SYSTOLIC STRAIN." Journal of the American College of Cardiology 65, no. 10 (March 2015): A1233. http://dx.doi.org/10.1016/s0735-1097(15)61233-5.

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Fernández Fernández, Laura, and Iñaki Lahuerta Martínez. "Los trucos para obtener un buen strain global longitudinal." Revista de Ecocardiografía Práctica y Otras Técnicas de Imagen Cardíaca, no. 1 (April 30, 2016): 65–67. http://dx.doi.org/10.37615/retic.n1a16.

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El estudio de los parámetros de deformación miocárdica (strain, strain rate…) permite establecer de forma cuantitativa la función sistólica del miocardio. Su uso aporta información muy valiosa en distintos escenarios clínicos y los equipos actuales disponen de la tecnología que permite su cálculo. Este artículo intenta describir los principios fundamentales del análisis de strain y algunos recursos necesarios a nivel de operador para optimizar esta técnica.

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Bewarder, Yvonne, Lucas Lauder, Saarraaken Kulenthiran, Ortwin Schäfer, Christian Ukena, Robert Percy Marshall, Pierre Hepp, et al. "Global longitudinal strain differentiates physiological hypertrophy from maladaptive remodeling." IJC Heart & Vasculature 40 (June 2022): 101044. http://dx.doi.org/10.1016/j.ijcha.2022.101044.

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Schuster, Andreas, Sören J. Backhaus, Thomas Stiermaier, and Ingo Eitel. "Prognostic utility of global longitudinal strain in myocardial infarction." World Journal of Cardiology 10, no. 5 (May 26, 2018): 35–37. http://dx.doi.org/10.4330/wjc.v10.i5.35.

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Sonny, Abraham, Andrej Alfirevic, Shiva Sale, Nicole M. Zimmerman, Jing You, A. Marc Gillinov, Daniel I. Sessler, and Andra E. Duncan. "Reduced Left Ventricular Global Longitudinal Strain Predicts Prolonged Hospitalization." Anesthesia & Analgesia 126, no. 5 (May 2018): 1484–93. http://dx.doi.org/10.1213/ane.0000000000002684.

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Oh, K., M. H. Mustehsan, S. R. Patel, D. B. Sims, S. Vukelic, S. Murthy, J. J. Shin, U. P. Jorde, and O. Saeed. "Intensified Statin Preserves Global Longitudinal Strain in Transplanted Heart." Journal of Heart and Lung Transplantation 39, no. 4 (April 2020): S253. http://dx.doi.org/10.1016/j.healun.2020.01.548.

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Coppin, A., A. Duva Pentiah, A. Coisne, H. Ridon, S. Mouton, P. De Groote, and D. Montaigne. "Multilayer vs. global 2D-longitudinal strain in hypertrophic cardiomyopathy." Archives of Cardiovascular Diseases Supplements 10, no. 2 (April 2018): 253–54. http://dx.doi.org/10.1016/j.acvdsp.2018.02.168.

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Coppin, A., A. Duva Pentiah, A. Coisne, H. Ridon, Stephanie Mouton, Pascal De Groote, and David Montaigne. "Multilayer vs. global 2D-longitudinal strain in hypertrophic cardiomyopathy." Archives of Cardiovascular Diseases Supplements 11, no. 1 (January 2019): 54–55. http://dx.doi.org/10.1016/j.acvdsp.2018.10.118.

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Blumenkrants, Dmitry, Mark Berlacher, Reginald E. Dunn, Richard Kovacs, Harvey Feigenbaum, Andrew Tucker, Andrew Lincoln, and Michael Emery. "GLOBAL & BASAL LONGITUDINAL STRAIN IN NFL COMBINE PARTICIPANTS." Journal of the American College of Cardiology 69, no. 11 (March 2017): 1417. http://dx.doi.org/10.1016/s0735-1097(17)34806-4.

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Vallabhajosyula, Saraschandra, and Jacob C. Jentzer. "Global Longitudinal Strain Using Speckle-Tracking Echocardiography in Sepsis." Journal of Intensive Care Medicine 34, no. 4 (September 11, 2018): 352. http://dx.doi.org/10.1177/0885066618799636.

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Negishi, Kazuaki, Tomoko Negishi, Koji Kurosawa, Krasimira Hristova, Bogdan A. Popescu, Dragos Vinereanu, Satoshi Yuda, and Thomas H. Marwick. "Practical Guidance in Echocardiographic Assessment of Global Longitudinal Strain." JACC: Cardiovascular Imaging 8, no. 4 (April 2015): 489–92. http://dx.doi.org/10.1016/j.jcmg.2014.06.013.

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Tower-Rader, Albree, Divyanshu Mohananey, Andrew To, Harry M. Lever, Zoran B. Popovic, and Milind Y. Desai. "Prognostic Value of Global Longitudinal Strain in Hypertrophic Cardiomyopathy." JACC: Cardiovascular Imaging 12, no. 10 (October 2019): 1930–42. http://dx.doi.org/10.1016/j.jcmg.2018.07.016.

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Zhang, Kun, Alexander Braun, Francisca von Koeckritz, Rosa B. Schmuck, Eva M. Teegen, Cesare Cuspidi, Frank Heinzel, Burkert Pieske, and Marijana Tadic. "Right Heart Remodeling in Patients with End-Stage Alcoholic Liver Cirrhosis: Speckle Tracking Point of View." Journal of Clinical Medicine 8, no. 9 (August 22, 2019): 1285. http://dx.doi.org/10.3390/jcm8091285.

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Background: Data regarding cardiac remodeling in patients with alcoholic liver cirrhosis are scarce. We sought to investigate right atrial (RA) and right ventricular (RV) structure, function, and mechanics in patients with alcoholic liver cirrhosis. Methods: This retrospective cross-sectional investigation included 67 end-stage cirrhotic patients, who were referred for evaluation for liver transplantation and 36 healthy controls. All participants underwent echocardiographic examination including strain analysis, which was performed offline. Results: RV basal diameter and RV thickness were significantly higher in patients with cirrhosis. Conventional parameters of the RV systolic function were similar between the observed groups. Global, endocardial, and epicardial RV longitudinal strains were significantly lower in patients with cirrhosis. Active RA function was significantly higher in cirrhotic patients than in controls. The RA reservoir and conduit strains were significantly lower in cirrhotic patients, while there was no difference in the RA contractile strain. Early diastolic and systolic RA strain rates were significantly lower in cirrhotic patients than in controls, whereas there was no difference in the RA late diastolic strain rate between the two groups. Transaminases and bilirubin correlated negatively with RV global longitudinal strain and RV-free wall strain in patients with end-stage liver cirrhosis. The Model for End-stage Liver Disease (MELD) score, predictor of 3-month mortality, correlated with parameters of RV structure and systolic function, and RA active function in patients with end-stage liver cirrhosis. Conclusions: RA and RV remodeling is present in patients with end-stage liver cirrhosis even though RV systolic function is preserved. Liver enzymes, bilirubin, and the MELD score correlated with RV and RA remodeling.

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Palmer, Gwen, Timothy J. Hibberd, Tiina Roose, Simon J. H. Brookes, and Mark Taylor. "Measurement of strains experienced by viscerofugal nerve cell bodies during mechanosensitive firing using digital image correlation." American Journal of Physiology-Gastrointestinal and Liver Physiology 311, no. 5 (November 1, 2016): G869—G879. http://dx.doi.org/10.1152/ajpgi.00397.2015.

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Mechanosensory neurons detect physical events in the local environments of the tissues that they innervate. Studies of mechanosensitivity of neurons or nerve endings in the gut have related their firing to strain, wall tension, or pressure. Digital image correlation (DIC) is a technique from materials engineering that can be adapted to measure the local physical environments of afferent neurons at high resolution. Flat-sheet preparations of guinea pig distal colon were set up with arrays of tissue markers in vitro. Firing of single viscerofugal neurons was identified in extracellular colonic nerve recordings. The locations of viscerofugal nerve cell bodies were inferred by mapping firing responses to focal application of the nicotinic receptor agonist 1,1-dimethyl-4-phenylpiperazinium iodide. Mechanosensory firing was recorded during load-evoked uniaxial or biaxial distensions. Distension caused movement of surface markers which was captured by video imaging. DIC tracked the markers, interpolating the mechanical state of the gut at the location of the viscerofugal nerve cell body. This technique revealed heterogeneous load-evoked strain within preparations. Local strains at viscerofugal nerve cell bodies were usually smaller than global strain measurements and correlated more closely with mechanosensitive firing. Both circumferential and longitudinal strain activated viscerofugal neurons. Simultaneous loading in circumferential and longitudinal axes caused the highest levels of viscerofugal neuron firing. Multiaxial strains, reflecting tissue shearing and changing area, linearly correlated with mechanosensory firing of viscerofugal neurons. Viscerofugal neurons were mechanically sensitive to both local circumferential and local longitudinal gut strain, and appear to lack directionality in their stretch sensitivity.

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Akam-Venkata, Jyothsna, Gilda Kadiu, James Galas, Steven E. Lipshultz, and Sanjeev Aggarwal. "Left ventricle segmental function in childhood cancer survivors using speckle-tracking echocardiography." Cardiology in the Young 29, no. 12 (November 27, 2019): 1494–500. http://dx.doi.org/10.1017/s1047951119002622.

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AbstractAim:Anthracycline-associated cardiotoxicity in childhood cancer survivors may relate to global or segmental left ventricular abnormalities from associated thromboembolic events and myocardial microinfarcts. We characterized left ventricular segmental changes by two-dimensional speckle-tracking echocardiography in anthracycline-treated asymptomatic childhood cancer survivors.Methods and Results:Childhood cancer survivors’ echocardiograms with normal left ventricular fractional shortening >1 year after anthracycline chemotherapy were studied. Cancer-free control children had normal echocardiograms. Apical two-, three-, and four-chamber peak systolic left ventricular longitudinal and global longitudinal strain, and peak systolic left ventricular radial and circumferential strain at papillary muscle levels were analyzed. The mean (standard deviation) age was 12.7 (3.8) years in 41 childhood cancer survivors. The median (interquartile range) follow-up after anthracycline chemotherapy was 4.73 (2.15–8) years. The median (range) cumulative anthracycline dose was 160.2 (60–396.9) mg/m2. In childhood cancer survivors, the mean (standard deviation) left ventricular longitudinal strain was lower in two- (−18.6 [3.2] versus −21.3 [2.5], p < 0.001), three- (−16.3 [6.0] versus −21.7 [3.0], p < 0.001), and four- (−17.6 [2.7] versus −20.8 [2.0], p < 0.001) chamber views compared to controls. The left ventricular global longitudinal strain (−17.6 [2.7] versus −21.3 [2.0]) and circumferential strain (−20.8 [4.3] versus −23.5 [2.6], p < 0.001) were lower in childhood cancer survivors. Among childhood cancer survivors, 12 out of 16 left ventricular segments had significantly lower longitudinal strain than controls.Conclusions:Asymptomatic anthracycline-treated childhood cancer survivors with normal left ventricular fractional shortening had lower global longitudinal and circumferential strain. The left ventricular longitudinal strain was lower in majority of the segments, suggesting that anthracycline cardiotoxicity is more global than regional.

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Velagapudi, Venu Madhav, Rahul Pidikiti, and Dennis A. Tighe. "Is Left Ventricular Global Longitudinal Strain by Two-Dimensional Speckle Tracking Echocardiography in Sepsis Cardiomyopathy Ready for Prime Time Use in the ICU?" Healthcare 7, no. 1 (January 3, 2019): 5. http://dx.doi.org/10.3390/healthcare7010005.

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Myocardial deformation imaging (strain imaging) is a technique to directly quantify the extent of myocardial contractility and overcomes several of the limitations of ejection fraction. The application of the most commonly used strain imaging method; speckle-tracking echocardiography to patients with sepsis cardiomyopathy heralds an exciting development to the field. However; the body of evidence and knowledge on the utility, feasibility and prognostic value of left ventricular global longitudinal strain in sepsis cardiomyopathy is still evolving. We conducted a review of literature on utility of left ventricular global longitudinal strain in sepsis cardiomyopathy. We discuss the role of left ventricular global longitudinal strain in mortality prediction, utility and limitations of the technique in the context of sepsis cardiomyopathy.

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Castel, Anne-Laure, Aymeric Menet, Pierre-Vladimir Ennezat, François Delelis, Caroline Le Goffic, Camille Binda, Raphaëlle-Ashley Guerbaai, et al. "Global longitudinal strain software upgrade: Implications for intervendor consistency and longitudinal imaging studies." Archives of Cardiovascular Diseases 109, no. 1 (January 2016): 22–30. http://dx.doi.org/10.1016/j.acvd.2015.08.006.

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48

Lu, Dai-Yin, Wei-Ming Huang, Wei-Ting Wang, Sheng-Che Hung, Shih-Hsien Sung, Chen-Huan Chen, Yu-Jou Yang, Dau-Ming Niu, and Wen-Chung Yu. "Reduced global longitudinal strain as a marker for early detection of Fabry cardiomyopathy." European Heart Journal - Cardiovascular Imaging 23, no. 4 (October 23, 2021): 487–95. http://dx.doi.org/10.1093/ehjci/jeab214.

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Abstract Aims Fabry cardiomyopathy (FC) is characterized by progressive left ventricular hypertrophy (LVH). Conventional echocardiography is not sensitive in detecting preclinical FC before the development of LVH. We aim to investigate whether myocardial deformation analysis is useful to detect preclinical FC before LVH. Methods and results One hundred and sixty patients carrying mutated gene were prospectively enrolled, including 86 patients without LVH and 74 patients with LVH. Another 33 healthy individuals were also included for comparison. Standard transthoracic two-dimensional, Doppler, tissue Doppler echocardiography and deformation analysis were performed. The mean age of the overall 193 subjects was 48 ± 15 years, with 51% men. Fabry patients with LVH were older, more often to be men. They also had the worst diastolic function as evidenced by the largest left atrium, lowest E/A, and highest E/e′ ratio. The global longitudinal strain (GLS) deteriorated with the development of LVH (control vs. LVH− patients vs. LVH+ patients = −21.2 ± 2.7 vs. −19.0 ± 2.9 vs. −16.5 ± 4.2%, P < 0.001). Despite similar LV systolic, diastolic function, and LV mass, LVH− Fabry patients still had a reduced GLS as well as regional longitudinal strains at mid-to-apical, anterior, and inferolateral wall when compared to healthy subjects. The basal longitudinal strain was consistently worse in male patients than in female patients, irrespective of LVH. Conclusion Reduced GLS could be a marker of early FC before the development of LVH.

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Toma, Daniela, Rodica Toganel, Amalia Fagarasan, Manuela Cucerea, Dorottya Gabor-Miklosi, Andreea Cerghit-Paler, Diana-Ramona Iurian, et al. "Interobserver Agreement and Reference Intervals for Biventricular Myocardial Deformation in Full-Term, Healthy Newborns: A 2D Speckle-Tracking Echocardiography-Based Strain Analysis." International Journal of Environmental Research and Public Health 19, no. 14 (July 15, 2022): 8620. http://dx.doi.org/10.3390/ijerph19148620.

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Data regarding reference intervals for strain parameters derived from 2D speckle-tracking echocardiography in full-term newborns are limited and still under development. Our objectives were to establish the level of reproducibility and reference intervals in assessing myocardial function using 2D speckle-tracking echocardiography for longitudinal and regional strain measurements. A total of 127 full-term newborns were examined to be included in the study, of which 103 were analyzed. We used two-dimensional acquisitions from apical four-chamber view of both ventricles and analyzed the autostrain function offline. We obtained interobserver agreement between the two observers ranging from good to excellent for all speckle-tracking parameters except for the strain of the medial portion of the left ventricle (LV) lateral wall and the strain measured on the basal portion of the inter-ventricular septum, which reflected a fair interobserver reproducibility (ICC = 0.52, 95% IC: 0.22–0.72 and ICC = 0.43, 95% IC: 0.12–0.67, respectively). The reference values obtained for the LV peak longitudinal strain were between −24.65 and −14.62, those for the right ventricle (RV) free wall were from −28.69 to −10.68, and those for the RV global four-chamber were from −22.30 to −11.37. In conclusion, two-dimensional peak longitudinal LV and RV strains are reproducible with good to excellent agreement and may represent a possible alternative for the cardiac assessment of healthy newborns in the clinical practice.

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Samuel Avila, Monica, Marco Stephan Lofrano Alves, Silvia Moreira Ayub-Ferreira, Mauro Rogerio de Barros Wanderley Junior, Fatima das Dores Cruz, Sara Michelly Gonçalves Brandão, Ludhmila Abrahão Hajjar, et al. "Global Longitudinal Strain as Predictor of Chemotherapy-Induced Cardiotoxicity." ABC Imagem Cardiovascular 35, no. 4 (December 21, 2022). http://dx.doi.org/10.47593/2675-312x/20223504eabc340p.

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Fundamento: A cardiotoxicidade induzida por quimioterapia (CiC) é uma complicação importante entre os pacientes que recebem antraciclinas. Biomarcadores e parâmetros de imagem têm sido estudados por sua capacidade de identificar pacientes com risco de desenvolver essa complicação. O strain longitudinal global do ventrículo esquerdo (SLG-VE) tem sido descrito como um parâmetro sensível para detectar disfunção sistólica, mesmo na presença de fração de ejeção do ventrículo esquerdo (FEVE) preservada. Objetivo: avaliar o papel do SLG-VE como preditor de CiC. Métodos: O presente estudo consiste em uma análise post-hoc do estudo CECCY (Carvedilol for Prevention of ChemotherapyRelated Cardiotoxicity [Carvedilol para Prevenção da Cardiotoxicidade Relacionada à Quimioterapia]), que avaliou a prevenção primária de cardiotoxicidade com carvedilol durante quimioterapia com doxorrubicina em uma população com câncer de mama. Definiu-se cardiotoxicidade como uma redução >10% na FEVE. O SLG-VE foi obtido antes da quimioterapia em pacientes sem doença cardiovascular prévia ou anormalidades no ecocardiograma. Resultados: Trinta e um pacientes submetidos a estudo ecocardiográfico completo incluindo avaliação de SLG-VE antes da quimioterapia foram incluídos nesta análise. Um SLG-VE absoluto <16,9% antes da quimioterapia mostrou 100% de sensibilidade e 73% de especificidade para predizer cardiotoxicidade (AUC=0,85; IC 95% 0,680–0,959, p<0,001). Nesta população, os valores de FEVE antes da quimioterapia não foram preditores de CiC (IC 95% 0,478 a -0,842, p=0,17). A associação de baixos níveis séricos de SLG-VE (<17%) e BNP (>17 pg/mL) dois meses após a quimioterapia aumentou a precisão para detectar CiC de início precoce (100% de sensibilidade, 88% de especificidade, AUC=0,94; IC 95% 0,7810,995, p<0,0001). Conclusões: Nossos dados sugerem que o SLG-VE é um possível preditor de cardiotoxicidade induzida por quimioterapia. São necessários estudos maiores para confirmar a relevância clínica desse parâmetro ecocardiográfico nesse cenário clínico.

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Journal articles on the topic 'Strain longitudinale globale'

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