Journal articles on the topic 'Stock options Australia'
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1
Seamer, Michael, and Adrian Melia. "Remunerating non-executive directors with stock options: who is ignoring the regulator?" Accounting Research Journal 28, no. 3 (November 2, 2015): 251–67. http://dx.doi.org/10.1108/arj-12-2013-0092.
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Purpose – This paper aims to investigate the incidence of remunerating Australian Securities Exchange (ASX)-listed non-executive directors (NEDs) with options and to determine whether companies that fail to adhere to NED remuneration recommendations share a common corporate governance profile. Despite corporate regulators condemning the practice of remunerating NEDs with stock options, there is a paucity of evidence regarding its prevalence in Australia. Design/methodology/approach – Focusing on ASX400 companies during 2008, a series of hypotheses relating NED stock option remuneration and corporate governance are tested using logistic regression. Findings – The study shows that the prevalence and quantum of NED option payments during 2008 was considerable with 73 of the ASX400 companies, including options in NED remuneration (option payers). Comparison of the corporate governance characteristics of option payers to that of a matched control group (non-option payers) highlighted both the existence and independence of the remuneration committee as critical in ensuring NED remuneration practices comply with regulator recommendations. Research limitations/implications – These results provide regulators and stakeholder groups with additional evidence to continue to call for corporate governance reforms to ensure that corporate remuneration practices are in the best interest of shareholders. Originality/value – This study is the first to highlight the extent to which Australian-listed company NED remuneration practices fail to comply with regulator recommendations and adds to the limited research on remuneration committee effectiveness.
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Boyd, Tristan, Philip Brown, and Alex Szimayer. "What determines early exercise of employee stock options in Australia?" Accounting & Finance 47, no. 2 (June 2007): 165–85. http://dx.doi.org/10.1111/j.1467-629x.2007.00211.x.
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Holmes, Karen W., Andrew Wherrett, Adrian Keating, and Daniel V. Murphy. "Meeting bulk density sampling requirements efficiently to estimate soil carbon stocks." Soil Research 49, no. 8 (2011): 680. http://dx.doi.org/10.1071/sr11161.
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Estimation of soil organic carbon stocks requires bulk density (BD) measurements. Variability in BD contributes to carbon stock uncertainty, in turn affecting how large a change in stock can be observed over time or space. However, BD is difficult and time-consuming to measure, and sample collection is further complicated by extremely dry field conditions, coarse-textured soils, and high coarse-fragment content, which are common in southern Australia and other semi-arid and Mediterranean-type climates. Two alternatives to reduce BD sampling effort are to take fewer BD samples at a site (i.e. volumetric rings or clod), and to use more time-efficient methods (i.e. gamma–neutron density meter, NDM). We evaluate these options in the context of a soil carbon stock survey in agricultural land in the south-west of Australia. The BD values within a monitoring site measured with conventional and NDM methods were statistically different when assessed using large sample sizes; the measurements diverged where the coarse fraction volume was >20%. However, carbon stocks were equivalent, reflecting the much larger relative variability in carbon percentage, which contributed 84–99% of the uncertainty in carbon stocks compared with <5% from BD. Given the maximum variability measured, soil carbon stock changes in southern Australia should be monitored on a decadal scale.
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Hobbes, Garry, Frewen Lam, and Geoffrey F. Loudon. "Regime Shifts in the Stock–Bond Relation in Australia." Review of Pacific Basin Financial Markets and Policies 10, no. 01 (March 2007): 81–99. http://dx.doi.org/10.1142/s0219091507000969.
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Previous evidence suggests that the implied volatility from equity index options, as a measure of stock market uncertainty, can provide "forward-looking information" about the stock–bond return correlation. This paper uses an alternative regime-switching autoregressive model to characterize state-dependent stock–bond return comovement and to evaluate the contribution of implied volatility in understanding transition dynamics. We confirm that implied volatility provides information about transition dynamics which is not inherent in the stock and bond returns, notwithstanding several different features of our data set and methodological approach.
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Wong, James Pow Chew. "Building energy performance assessment for existing commercial buildings with heritage values." MATEC Web of Conferences 277 (2019): 03018. http://dx.doi.org/10.1051/matecconf/201927703018.
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The building sector accounts for 19% of Australia's energy consumption and around 23% of the greenhouse gas emissions. In 2005, commercial buildings in Australia were responsible for 10% or 26 megatonnes (Mt) of the nation's greenhouse gas emissions. They are two effective ways to reduce the building sector's emissions, namely constructing new energy efficient buildings or retrofitting existing buildings. Due to the life expectancy of existing building stock the greatest reduction in emissions before 2030 could be achieved through retrofits. Building performance assessment and evaluation uses predictive modelling method to investigate and evaluate building performance in energy demands, thermal occupant comfort, indoor air quality, building retrofit options and many other related environmental and wellbeing aspects. This paper discussed the use of building performance simulation software to investigate the impacts of various retrofit options have onto energy performance of existing commercial buildings with heritage values in Australia. The research explores the use of thermal and airflow modelling in assisting understanding of building energy performance with various retrofit options applied to existing commercial buildings. The finding highlights the capabilities of building performance simulation software in decision making for building performance investigations.
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Cooney, Rosie, Alex Baumber, Peter Ampt, and George Wilson. "Sharing Skippy: how can landholders be involved in kangaroo production in Australia?" Rangeland Journal 31, no. 3 (2009): 283. http://dx.doi.org/10.1071/rj08025.
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For 2 decades, calls for Australian rangeland landholders to expand their reliance on the abundant species of native kangaroos and decrease their reliance on introduced stock have been made. These calls have received recent impetus from the challenge of climate change. Arguments for landholder involvement in kangaroo production include reduced greenhouse gas emissions, better management of total grazing pressure, reduced land degradation, improved vegetation and biodiversity outcomes, and greater valuation of kangaroos by landholders. However, there is little understanding of how landholders could be involved in kangaroo harvest and production, and there is a widespread misconception that this would include domestication, fencing, mustering and trucking. This paper reviews the options for landholder involvement in managing and harvesting wild kangaroos, and assesses the possible benefits and feasibility of such options. We conclude that collaboration among landholders, as well as between landholders and harvesters, forms the basis of any preferred option, and set out a proposed operating model based on the formation of a kangaroo management, processing and marketing co-operative.
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Ward, T. M., P. J. Rogers, L. J. McLeay, and R. McGarvey. "Evaluating the use of the Daily Egg Production Method for stock assessment of blue mackerel, Scomber australasicus." Marine and Freshwater Research 60, no. 2 (2009): 112. http://dx.doi.org/10.1071/mf08134.
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The present study evaluates the suitability of the Daily Egg Production Method (DEPM) for stock assessment of blue mackerel, Scomber australasicus and assesses methodological options for future applications. In southern Australia, estimates of mean daily egg production were higher for Californian Vertical Egg Tow (CalVET) nets than bongo nets, and in eastern Australia, were higher in October 2003 than July 2004. Estimates of spawning area for southern Australia were three times higher for bongo nets than CalVET nets. Similar estimates of spawning area were obtained using standard (manual) gridding and natural neighbour methods. Large samples and reliable estimates of all adult parameters were obtained for southern Australia. Relatively few spawning adults were collected off eastern Australia. Preliminary best estimates of spawning biomass for southern and eastern Australia were 56 228 t and 29 578 t, respectively, with most estimates within the ranges of 45 000–68 000 t and 20 000–40 000 t respectively. The DEPM is suitable for stock assessment of S. australasicus. Several technical refinements are required to enhance future applications, including: genetic techniques for identifying early stage eggs; a temperature–egg development key; improved methods for sampling adults off eastern Australia; and measurements of the degeneration rates of post-ovulatory follicles at several temperatures.
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Pitcher, C. Roland, Darren M. Dennis, and Timothy D. Skewes. "Fishery-independent surveys and stock assessment of Panulirus ornatus in Torres Strait." Marine and Freshwater Research 48, no. 8 (1997): 1059. http://dx.doi.org/10.1071/mf97199.
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The Torres Strait lobster fishery differs culturally and ecologically from other Australian lobster fisheries. Ornate rock lobsters (Panulirus ornatus) have been fished by the inhabitants of Torres Strait for centuries, and commercial fishing began in the late 1960s. The fishery is a major source of income for Torres Strait Islanders, and the aim of management is to balance the needs of traditional and commercial users under a treaty between Australia and Papua New Guinea. In 1989, the absolute abundance of lobsters in the main fishing grounds was estimated by a visual census and a simple assessment was made. Since then, annual fishery-independent surveys of the relative stock abundance, and catch sampling, have contributed to the development of a simple cohort dynamics model of the fishery; for a range of fishing mortalities, it estimates the potential yield and percentage escapement and has provided annual assessments of the status of the stock and potential yield one year in advance— information valuable for managers considering development options and negotiating catch-sharing agreements and access rights. Future research will develop the model by incorporating information from ongoing surveys, catch recording, and logbook data from the Australian and Papua New Guinean fisheries.
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Thomson, Dianne, and Ameeta Jain. "Corporate Governance Failure And Its Impact On National Australia Banks Performance." Journal of Business Case Studies (JBCS) 2, no. 1 (January 1, 2006): 41–56. http://dx.doi.org/10.19030/jbcs.v2i1.4879.
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The National Australia Bank (NAB) is the largest financial services institution listed on the Australian stock exchange and is within the 30 most profitable financial services organisation in the world. In January 2004, the bank disclosed to the public that it had identified losses relating to unauthorised trading in foreign currency options amounting to AUD360 million. This foreign exchange debacle was classified as operational risk, the risk of loss resulting from inadequate or failed processes, people, or systems and reiterated the importance of corporate governance for banks. Concurrent issues of National Australia Banks AUD4.1 billion loss on US HomeSide loans in 2001, the degree of strength of their risk management practices and lack of auditor independence, were raised by the US Securities and Exchange Commission in 2004, reinforcing the view that corporate governance had not been given the priority it deserved over a number of years. This paper will assess and critically analyse the impact of corporate governance failure by management and Board of Directors on NABs performance over the years 2001-2005.
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Johnson, I. R., D. F. Chapman, V. O. Snow, R. J. Eckard, A. J. Parsons, M. G. Lambert, and B. R. Cullen. "DairyMod and EcoMod: biophysical pasture-simulation models for Australia and New Zealand." Australian Journal of Experimental Agriculture 48, no. 5 (2008): 621. http://dx.doi.org/10.1071/ea07133.
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DairyMod and EcoMod, which are biophysical pasture-simulation models for Australian and New Zealand grazing systems, are described. Each model has a common underlying biophysical structure, with the main differences being in their available management options. The third model in this group is the SGS Pasture Model, which has been previously described, and these models are referred to collectively as ‘the model’. The model includes modules for pasture growth and utilisation by grazing animals, water and nutrient dynamics, animal physiology and production and a range of options for pasture management, irrigation and fertiliser application. Up to 100 independent paddocks can be defined to represent spatial variation within a notional farm. Paddocks can have different soil types, nutrient status, pasture species, fertiliser and irrigation management, but are subject to the same weather. Management options include commonly used rotational grazing management strategies and continuous grazing with fixed or variable stock numbers. A cutting regime simulates calculation of seasonal pasture growth rates. The focus of the present paper is on recent developments to the management routines and nutrient dynamics, including organic matter, inorganic nutrients, leaching and gaseous nitrogen losses, and greenhouse gases. Some model applications are presented and the role of the model in research projects is discussed.
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Čirjevskis, Andrejs. "Measuring Collaborative Synergies with Advanced Real Options: MNEs’ Sequential Acquisitions of International Ventures." Journal of Risk and Financial Management 16, no. 1 (December 26, 2022): 11. http://dx.doi.org/10.3390/jrfm16010011.
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This paper aims to extend the real options theory valuing strategic collaborative synergies by advanced real options with changing volatility and contributes to the international business literature on MNEs’ sequential acquisitions of international ventures. The proposition is that collaborative synergies can be valued with advanced real options with changing volatility when an MNE is pursuing the sequential acquisition of an international venture and the MNE’s stock volatility is changing at the time of deciding on a full takeover. The paper discusses how recombining and non-recombining lattices with constant and changing volatilities can be employed to value the collaborative synergies of sequential international acquisitions. The theoretical proposition has been justified with the explanatory case study: Natura Cosméticos S.A.’s (Brazil) sequential acquisition of the Aesop brand (Australia). In conclusion, the paper discusses its findings, contributions, limitations, and future work.
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Siddique, K. H. M., and J. Sykes. "Pulse production in Australia past, present and future." Australian Journal of Experimental Agriculture 37, no. 1 (1997): 103. http://dx.doi.org/10.1071/ea96068.
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Summary. Several cool- and warm-season pulse crops (grain legumes) are grown in rotation with cereals and pasture forming sustainable farming systems in Australia. Australian pulse production has increased rapidly over the past 25 years to about 2 x 106 t/year, mainly because of the increase in the area and yield of lupin production for stockfeed purposes. Pulses currently comprise only 10% of the cropping areas of Australia and this could be expanded to 16% as there are large areas of soil types suitable for a range of pulse crops and new better-adapted pulse varieties are becoming available. Cool-season pulses will continue to dominate pulse production in Australia and the majority of the expansion will probably come from chickpea and faba bean industries. There appears to be no major constraint to pulse production in Australia that cannot be addressed by breeders, agronomists and farmers. Of the current major pulse crops, field pea faces the most number of difficulties, in particular the lack of disease management options. A recent strategic plan of the Australian pulse industry predicts the production of 4 x 106 t/year by 2005 but this will largely depend upon export demand and pulse prices. It is predicted that the growth in pulse production will come from increased productivity in the existing areas, from 1.0 to 1.4 t/ha, through improvements in crop management and the development of superior varieties. The area of pulse production will also expand by an additional 1.2 x 106 ha probably yielding 1.0 t/ha. If trends in grazing stock prices continue, the increased area under pulse production will mostly come at the expense of those areas under unimproved pasture and continuous cereal cropping.
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Konopleva, Marina, Nitin Jain, Courtney L. Andersen, Natalia Couto Francisco, Nairouz Elgeioushi, Rosalind Hobson, Martin Scott, et al. "NIMBLE: A Phase I/II Study of AZD0466 Monotherapy or in Combination in Patients with Advanced Hematological Malignancies." Blood 138, Supplement 1 (November 5, 2021): 2353. http://dx.doi.org/10.1182/blood-2021-147482.
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Abstract Introduction: While BCL2 inhibition benefits many patients with acute myeloid leukemia (AML), resistance often occurs due to upregulation of other anti-apoptotic proteins such as MCL and BCLxL. Dual BCL2/xL inhibition with AZD4320 has potential for broader activity than BCL2-specific inhibition with venetoclax (Balachander et al, Clinical Cancer Research 2020). AZD0466 is a drug-dendrimer conjugate in which AZD4320 is covalently conjugated to a pegylated poly-L-lysine dendrimer and where, following IV infusion, AZD4320 is gradually released by hydrolysis. The dendrimer construct allows for efficient delivery of the highly potent but poorly soluble active drug, and this release profile was designed to mitigate potential maximum concentration (Cmax)-dependent BCLxL mediated effects (Patterson et al, Nature Communications Biology 2021). AZD0466 has shown antitumor activity in a range of preclinical models of hematological malignancy, including cell-line derived and patient-derived xenograft models of acute myeloid leukemia (AML), B-cell acute lymphoblastic leukemia (B-ALL), and T-cell acute lymphoblastic leukemia (T-ALL - Kannan et al AACR 2020 Abstract 3075). AZD0466 has previously been administered to 9 patients with advanced solid malignancies at doses declared tolerable through 200 mg in the first-time-in-human study (NCT04214093), and a physiologically based PK model validated across nonclinical species was used to predict human doses and exposures expected to drive tumor regression in hematologic malignancy. These studies provide rationale for testing AZD0466 in refractory AML and ALL patients in this phase I/II dose escalation and monotherapy expansion and drug-drug interaction study (NCT04865419). Study Design and Methods: NIMBLE (drug deNdrIMer targeting BCL2/xL in acute LEukemias) is a modular, non-randomized phase I/II dose escalation and expansion study. Module 1 will evaluate safety, tolerability, pharmacokinetics, and preliminary efficacy of AZD0466 as monotherapy in patients with relapsed/refractory AML or ALL. Patients are eligible if ≥ 18 years of age with any subtypes of relapsed/refractory AML or ALL without active CNS involvement and after at least one prior line of therapy. Treatment with hydroxyurea during screening and cycle 1 is permitted to control white blood cell count. Patients with extramedullary disease are also eligible. Primary endpoints are safety and tolerability of AZD0466 in patients with acute leukemia. In dose escalation, patients will be treated in each dose level according to an mTPI-2 design. Secondary endpoints are to determine pharmacokinetic parameters for total and released AZD4320. Exploratory endpoints include association of pharmacodynamic effects including changes to peripheral blasts and cleaved caspase activation, and initial evaluation of efficacy in relation to baseline leukemia characteristics. Planned dose expansion cohorts are AML patients with a prior history of MPN with ≤ 2 prior lines of therapy, AML patients with TP53 mutation treated with ≤ 3 prior lines of therapy, other AML treated with ≤ 3 prior lines (including venetoclax), and B- or T-ALL treated with ≤ 3 prior lines. Module 2 is a drug-drug interaction (DDI) study that will investigate the safety and establish the sensitivity of AZD0466 to voriconazole, a strong inhibitor of CYP3A4. There are no additional inclusion or exclusion criteria specific to Module 2. Further modules will be added via protocol amendment to investigate AZD0466 in combination with other antileukemia treatments, and may be triggered at the planned interim analyses during expansion. AZD0466 will be administered with a dose ramp-up in cycle 1 from a starting dose on day 1, with subsequent titration to an intermediate dose on day 4, and target dose on day 8, with weekly 1-hour IV administration thereafter at the target dose. The duration of cycle 1 is 35 days, and subsequent cycles are 28 days in which AZD0466 will be administered once weekly. Patients will continue until treatment failure, unacceptable toxicity, or withdrawal of consent. This study is actively enrolling patients at sites in the USA, and will be opening at multiple sites in Australia, Europe and South Korea. An update of preliminary safety and pharmacokinetics will be presented. Figure 1 Figure 1. Disclosures Konopleva: AstraZeneca: Other: grant support, Research Funding; Sanofi: Other: grant support, Research Funding; AbbVie: Consultancy, Honoraria, Other: Grant Support, Research Funding; Genentech: Consultancy, Honoraria, Other: grant support, Research Funding; Eli Lilly: Patents & Royalties: intellectual property rights, Research Funding; Stemline Therapeutics: Research Funding; Forty Seven: Other: grant support, Research Funding; KisoJi: Research Funding; F. Hoffmann-La Roche: Consultancy, Honoraria, Other: grant support; Ascentage: Other: grant support, Research Funding; Ablynx: Other: grant support, Research Funding; Calithera: Other: grant support, Research Funding; Reata Pharmaceuticals: Current holder of stock options in a privately-held company, Patents & Royalties: intellectual property rights; Agios: Other: grant support, Research Funding; Rafael Pharmaceuticals: Other: grant support, Research Funding; Cellectis: Other: grant support; Novartis: Other: research funding pending, Patents & Royalties: intellectual property rights. Jain: Fate Therapeutics: Research Funding; Cellectis: Honoraria, Research Funding; Bristol Myers Squibb: Honoraria, Research Funding; AstraZeneca: Honoraria, Research Funding; Adaptive Biotechnologies: Honoraria, Research Funding; Genentech: Honoraria, Research Funding; Incyte: Research Funding; AbbVie: Honoraria, Research Funding; ADC Therapeutics: Honoraria, Research Funding; Precision Biosciences: Honoraria, Research Funding; Servier: Honoraria, Research Funding; Pfizer: Research Funding; Aprea Therapeutics: Research Funding; Pharmacyclics: Research Funding; Janssen: Honoraria; Beigene: Honoraria; TG Therapeutics: Honoraria. Andersen: AstraZeneca: Current Employment, Current equity holder in publicly-traded company. Couto Francisco: AstraZeneca: Current Employment, Other: may own stock or stock options. Elgeioushi: AstraZeneca: Current Employment, Other: may own stock or stock options. Hobson: AstraZeneca: Current Employment, Other: may own stock or stock options. Scott: AstraZeneca: Current Employment, Other: may own stock or stock options. Stone: AstraZeneca: Current Employment, Other: may own stock or stock options. Sharma: AstraZeneca: Current Employment, Current equity holder in publicly-traded company, Divested equity in a private or publicly-traded company in the past 24 months. Morentin Gutierrez: AstraZeneca: Current Employment, Other: may own stock or stock options. Tibes: AstraZeneca: Current Employment, Other: may own stock or stock options. Davies: AstraZeneca: Current Employment, Other: may own stock or stock options. Winkler: AstraZeneca: Current Employment, Other: may own stock or stock options. Fabbri: AstraZeneca: Current Employment, Other: may own stock or stock options. Zumla Cader: AstraZeneca: Current Employment, Other: may own stock or stock options. McNeer: AstraZeneca: Current Employment, Other: may own stock or stock options.
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Lum, Yew-Choe, and Sardar M. N. Islam. "Time Varying Behavior of Share Returns in Australia: 1988–2004." Review of Pacific Basin Financial Markets and Policies 19, no. 01 (March 2016): 1650004. http://dx.doi.org/10.1142/s0219091516500041.
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The model in this paper is similar to Brailsford and Faff (1997), using a conditional CAPM model with the GARCH-M framework, but with a significant additional dummy term (in the conditional mean of the share return) that will help explain the models better in both economic and statistical sense. The relatively simpler asymmetric model in this paper is compatible to other more complex asymmetric models and hence should be easier to model and explain for practical purposes. The model in this paper is also a more effective model, in both economical and statistical terms, as compared to some other models in the GARCH family as it captures the asymmetric effect in the modeling process in both the conditional first and second moments. The findings in this paper have contributed in re-evaluating the nature and process of time varying behavior of time series of stock returns and will provide researchers and practitioners additional options and incentives to explore for future research. We have also provided statistical and practical reasons to support these findings.
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Gourley, C. J. P., and D. M. Weaver. "Nutrient surpluses in Australian grazing systems: management practices, policy approaches, and difficult choices to improve water quality." Crop and Pasture Science 63, no. 9 (2012): 805. http://dx.doi.org/10.1071/cp12154.
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Nutrient surpluses, inefficiencies in nutrient use, and inevitable leakage of nutrients from grazed animal production systems are putting growing pressure on Australian inland and coastal water resources. While there are some examples of regulatory policy approaches in Australia which aim to reduce nutrient emissions and improve water quality around important and impaired coastal and inland waters, most policy options involve voluntary schemes, often including financial incentives to both industry organisations and farmers to offset the costs of implementing improved management practices. In contrast, much stronger land management regulations have been implemented in the European Union, USA, and to a lesser extent New Zealand. In the near future, greater societal expectations for water quality, stricter standards from international markets, and increasing costs for purchased nutrients will mean that improving nutrient-use efficiency and reducing nutrient losses will be a necessary part of Australia livestock production systems. This is likely to require somewhat varied and difficult choices to better balance production and environmental goals. Policy responses may include voluntary adoption of appropriate nutrient management practices, caps on nutrient inputs, mandatory nutrient surplus targets, limits to stock numbers per hectare, and re-positioning of higher input farms to more resilient parts of the national landscape. Alternatively, society may have to accept that there are unavoidable trade-offs between water quality standards and livestock productivity, with increasing treatment of polluted water at the community’s expense.
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Thuesen, P. A., D. J. Russell, F. E. Thomson, M. G. Pearce, T. D. Vallance, and A. E. Hogan. "An evaluation of electrofishing as a control measure for an invasive tilapia (Oreochromis mossambicus) population in northern Australia." Marine and Freshwater Research 62, no. 2 (2011): 110. http://dx.doi.org/10.1071/mf10057.
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Combating the spread of invasive fish is problematic, with eradication rarely possible and control options varying enormously in their effectiveness. In two small impoundments in north-eastern Australia, an electrofishing removal program was conducted to control an invasive tilapia population. We hypothesised that electrofishing would reduce the population density of Oreochromis mossambicus (Mozambique tilapia), to limit the risk of downstream spread into areas of high conservation value. We sampled by electrofishing monthly for 33 months. Over this period, there was an 87% decline in catch per unit effort (CPUE) of mature fish, coupled with a corresponding increase of 366% in the number of juveniles, suggesting a density-dependent response in the stock–recruitment relationship for the population. Temperature was inversely related to CPUE (r = 0.43, lag = 10 days), implying greater electrofishing efficiency in cooler months. The reduction in breeding stock is likely to reduce the risk of spread and render the population vulnerable to other control measures such as netting and/or biological control. Importantly, the current study suggests routine electrofishing may be a useful control tool for invasive fish in small impoundments when the use of more destructive techniques, such as piscicides, is untenable.
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Cottle, D., R. Eckard, S. Bray, and M. Sullivan. "An evaluation of carbon offset supplementation options for beef production systems on coastal speargrass in central Queensland, Australia." Animal Production Science 56, no. 3 (2016): 385. http://dx.doi.org/10.1071/an15446.
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In 2014, the Australian Government implemented the Emissions Reduction Fund to offer incentives for businesses to reduce greenhouse gas (GHG) emissions by following approved methods. Beef cattle businesses in northern Australia can participate by applying the ‘reducing GHG emissions by feeding nitrates to beef cattle’ methodology and the ‘beef cattle herd management’ methods. The nitrate (NO3) method requires that each baseline area must demonstrate a history of urea use. Projects earn Australian carbon credit units (ACCU) for reducing enteric methane emissions by substituting NO3 for urea at the same amount of fed nitrogen. NO3 must be fed in the form of a lick block because most operations do not have labour or equipment to manage daily supplementation. NO3 concentrations, after a 2-week adaptation period, must not exceed 50 g NO3/adult animal equivalent per day or 7 g NO3/kg dry matter intake per day to reduce the risk of NO3 toxicity. There is also a ‘beef cattle herd management’ method, approved in 2015, that covers activities that improve the herd emission intensity (emissions per unit of product sold) through change in the diet or management. The present study was conducted to compare the required ACCU or supplement prices for a 2% return on capital when feeding a low or high supplement concentration to breeding stock of either (1) urea, (2) three different forms of NO3 or (3) cottonseed meal (CSM), at N concentrations equivalent to 25 or 50 g urea/animal equivalent, to fasten steer entry to a feedlot (backgrounding), in a typical breeder herd on the coastal speargrass land types in central Queensland. Monte Carlo simulations were run using the software @risk, with probability functions used for (1) urea, NO3 and CSM prices, (2) GHG mitigation, (3) livestock prices and (4) carbon price. Increasing the weight of steers at a set turnoff month by feeding CSM was found to be the most cost-effective option, with or without including the offset income. The required ACCU prices for a 2% return on capital were an order of magnitude higher than were indicative carbon prices in 2015 for the three forms of NO3. The likely costs of participating in ERF projects would reduce the return on capital for all mitigation options.
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Emery, David Lyall. "Approaches to Integrated Parasite Management (IPM) for Theileria orientalis with an Emphasis on Immunity." Pathogens 10, no. 9 (September 7, 2021): 1153. http://dx.doi.org/10.3390/pathogens10091153.
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Integrated parasite management (IPM) for pests, pathogens and parasites involves reducing or breaking transmission to reduce the impact of infection or infestation. For Theileria orientalis, the critical impact of infection is the first wave of parasitaemia from the virulent genotypes, Ikeda and Chitose, associated with the sequelae from the development of anaemia. Therefore, current control measures for T. orientalis advocate excluding the movement of naïve stock from non-endemic regions into infected areas and controlling the tick Haemaphysalislongicornis, the final host. In Australia, treatment of established infection is limited to supportive therapy. To update and expand these options, this review examines progress towards prevention and therapy for T. orientalis, which are key elements for inclusion in IPM measures to control this parasite.
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Seo, Seongwon, and Greg Foliente. "Carbon Footprint Reduction through Residential Building Stock Retrofit: A Metro Melbourne Suburb Case Study." Energies 14, no. 20 (October 12, 2021): 6550. http://dx.doi.org/10.3390/en14206550.
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Since existing residential buildings are a significant global contributor to energy consumption and greenhouse gas (GHG) emissions, any serious effort to reduce the actual energy and carbon emissions of the building sector should explicitly address the carbon mitigation challenges and opportunities in the building stock. This research investigates environmentally and economically sustainable retrofit methods to reduce the carbon footprint of existing residential buildings in the City of Greater Dandenong as a case study in Metropolitan Melbourne, Australia. By categorizing energy use into various building age brackets and dwelling types that align with changes in energy regulations, we identified various retrofit prototypes to achieve a targeted 6.5-star and 8-star energy efficiency rating (out of a maximum 10-star rating system). The corresponding operational energy savings through different retrofit options are examined while also considering the quantity of materials required for each option, along with their embodied energy and GHG emissions, thus allowing a more comprehensive lifecycle carbon analysis and exploration of their financial and environmental payback times. Results show that when buildings are upgraded with a combination of insulation and double-glazed windows, the environmental benefits rise faster than the financial benefits over a dwelling’s lifecycle. The size or percentage of a particular dwelling type within the building stock and the remaining lifecycle period are found to be the most important factors influencing the payback periods. Retrofitting the older single detached dwellings shows the greatest potential for lifecycle energy and carbon savings in the case suburb. These findings provide households, industry and governments some guidance on how to contribute most effectively to reduce the carbon footprint of the residential building sector.
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Dobes, Leo. "Sir Sidney Kidman: Australia's cattle king as a pioneer of adaptation to climatic uncertainty." Rangeland Journal 34, no. 1 (2012): 1. http://dx.doi.org/10.1071/rj11045.
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There is little direct evidence about the business model used by the legendary cattle king, Sir Sidney Kidman. Kidman’s properties were invariably stocked at less than full capacity, and were generally contiguous, forming chains that straddled stock routes and watercourses in the most arid zone of central Australia. Railheads at the ends of the chains provided access to the main capital city markets, and Kidman’s drovers supplied a wealth of information on competing cattle movements. This combination of features effectively afforded strategic transport flexibility in the form of so-called ‘real options’, especially during severe region-wide droughts. Alternative perspectives, such as the vertical integration of Kidman’s operations, or spatial diversification of land holdings, offer only partial insights. Faced with a highly variable and unpredictable climate, combined with the onset of erosion and the spread of rabbits, Kidman exemplifies human ability to adapt creatively to exogenous environmental shocks such as climate change.
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Kalutara, Pushpitha, Guomin Zhang, Sujeeva Setunge, and Ron Wakefield. "Factors that influence Australian community buildings’ sustainable management." Engineering, Construction and Architectural Management 24, no. 1 (January 16, 2017): 94–117. http://dx.doi.org/10.1108/ecam-10-2015-0158.
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Purpose Australia has a huge stock of community buildings built up over decades. Their replacements consume a large sum of money from country’s economy which has called for a strategy for their sustainable management. For this, a comprehensive decision-making structure is an utmost requirement. The purpose of this paper is to capture their sustainable management from four aspects, i.e. environmental, economic, social and functional. Design/methodology/approach The design process follows an extensive review of environmental and life cycle assessments and company context documents. Extracted factors are tailored to community buildings management following expert consultation. However, the resulted list of factors is extremely large, and “factor analysis” technique is used to group the factors. For this, an industry-wide questionnaire across Australian local councils is employed to solicit opinions of the list of factors. Findings The analysis has pinpointed 18 key parameters (criteria) to represent all four aspects. This paper presents the preliminary findings of the factors and the analysis results based on the questionnaire responses. Practical implications The final decision-making structure incorporates all these aspects and criteria. This can be used to develop a decision-making model which produces a sustainability index for building components. Asset managers can mainly use the sustainability index to prioritise their maintenance activities and eventually, to find out cost-optimisation options for them. Originality/value Most notably, this is the first study to apply all four sustainability aspects (environmental, economic, social and functional) to develop a decision-making structure for Australian community buildings’ sustainable management.
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White, S., G. Milne, and C. Riedy. "End use analysis: issues and lessons." Water Supply 4, no. 3 (June 1, 2004): 57–66. http://dx.doi.org/10.2166/ws.2004.0043.
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Methodologies for end use analysis have been developed by different researchers in the energy and water fields and in different areas in the world over the last 20 years. While there are core features associated with the methodologies and models used, the differences can provide insight into the ways that they might be improved, as well as the differences that may be required in different regions and when models are used for different purposes. In addition to reviewing the field of end use analysis and appliance stock models, this paper will focus on two case studies. The first is the Sydney Water End Use Model, developed as part of the Sydney Water Least Cost Planning Study. This model has been developed and used to project the demand for water in Sydney over the next 20 years under business as usual scenario, as well as allow the projection of a number of scenarios which include major investment in water efficiency and effluent reuse programs as well as regulatory options to improve the efficiency of water using appliances in stalled in new buildings. Key features of the Sydney Water End Use Model include the fact that it takes into account the fact that the efficiency of toilets in Australia has a much larger range than (say) the US, in that the dual flush toilet was introduced in (to date) three stages. The model also accounts for projections of demographic and land use change which has been particularly dramatic in Sydney, particularly the movement to smaller occupancy rates in dwellings, and towards multi-family residential dwellings. The second case study will demonstrate the linkages between end use modeling of energy using and water using appliances. A model of residential energy use in Australia has been developed as part of a research project to develop greenhouse abatement scenarios for Australia, and many of the appliances modeled overlap with the water end use model, including clothes washing machines, dishwashers, showerheads and taps. This more recent modeling exercise has revealed the importance of key assumptions in standard stock modeling techniques, and highlighted the need for earlier starting dates for stock modeling. The process and results of these two case studies will be presented, and conclusions drawn about further improvements in end use analysis for both water and energy use. The linkage between the use of backcasting as a planning tool, and the use of end use analysis as a pre-requisite for the development of a demand management program is highlighted.
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Harrison, Simon, Michele Cavo, Javier De La Rubia, Rakesh Popat, Cristina Gasparetto, Vania T. M. Hungria, Hans Salwender, et al. "T(11;14) and High BCL2 Expression Are Predictive Biomarkers of Response to Venetoclax in Combination with Bortezomib and Dexamethasone in Patients with Relapsed/Refractory Multiple Myeloma: Biomarker Analyses from the Phase 3 Bellini Study." Blood 134, Supplement_1 (November 13, 2019): 142. http://dx.doi.org/10.1182/blood-2019-126094.
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Background: Overexpression of the anti-apoptotic BCL-2 protein promotes multiple myeloma (MM) cell survival. Venetoclax (Ven) is a highly selective, potent, oral BCL-2 inhibitor that induces apoptosis and has shown synergistic activity with bortezomib (B) and dexamethasone (d). Phase 1 studies in relapsed/refractory (RR) MM demonstrated encouraging clinical efficacy of Ven + d in t(11;14) MM and in a broader patient (pt) population in combination with Bd. Recent results from the Phase 3 BELLINI study of Ven vs placebo (Pbo) + Bd in pts with RRMM demonstrated that pts treated with Ven + Bd had improved clinical response rates and progression-free survival (PFS) vs Pbo, although the overall survival (OS) result was in favor of Pbo. Subgroup analyses showed different efficacy and survival outcomes based on tumor cytogenetics and BCL-2 expression. Results of pre-specified subgroup analyses and additional retrospective correlative biomarker analyses in the Phase 3 BELLINI study are described herein. Methods: BELLINI (NCT02755597) was a randomized, double-blind, multicenter Phase 3 study of Ven or Pbo + Bd in pts with RRMM who received 1-3 prior therapies and were either sensitive or naïve to PIs. Pts were randomized 2:1 to receive Ven 800 mg/day or Pbo + Bd. The following biomarker analyses were performed by central laboratory assessments of pre-treatment tumor samples: BCL-2 protein expression by immunohistochemistry (IHC) analysis of bone marrow (BM) core biopsies; BCL2 gene expression by quantitative PCR (qPCR) and cytogenetic abnormalities by interphase fluorescence in situ hybridization (FISH) analysis of CD138-enriched BM mononuclear cells. Correlation between BCL-2 (protein and gene) expression, cytogenetics, and outcomes were examined by Kruskal-Wallis tests and by hazard ratio (HR) using the Cox proportional hazard model. Results: As of the data cut-off of 18 Mar 2019, 291 pts were randomized, 194 to the Ven arm and 97 to the Pbo arm. Out of the 291 pts randomized, 177 pts (61%) were evaluable by IHC, 257 pts (88%) by qPCR, and 262 pts (90%) by FISH. A broad range of BCL2 gene expression was observed (median 2-DCt: 0.212 [range: 0-5.21]), which strongly correlated with protein expression (median 2-DCt 0.115 in BCL-2 IHC Low vs 0.277 in BCL-2 IHC High, p=0.0021). t(11;14) MM had the highest levels of BCL-2 expression (23/23 BCL-2 High by IHC; median 2-DCt 0.406 vs 0.212 in t(11;14) negative, p=0.0132), however high BCL-2 expression was not limited to the t(11;14) subgroup. Univariate analyses showed higher BCL2 expression in pt tumor samples with del(13q) (median 2-DCt 0.333 vs 0.159 in pts without del(13q), p=0.0008) and gain(1q) (median 2-DCt 0. 295 vs 0.180 in pts without gain(1q), p=0.0059). Bootstrapping and aggregating thresholds from trees (BATTing) was used retrospectively to identify an estimated threshold value for BCL2 expression (2-DCt ≥0.323) that could provide optimum selection of pts with maximum improvement in PFS when treated with Ven+Bd. Biomarker subgroups with the greatest PFS improvement were t(11;14) (HR=0.10; 95% CI: 0.02-0.46, p=0.003) and High BCL2 by qPCR (HR=0.26; 95% CI: 0.13-0.51, p<0.001; Table 1). Since the t(11;14) and High BCL2 patient populations do not completely overlap (20% of High BCL2 pts were t(11;14) and 54% of t(11;14) were High BCL2), a combined subgroup analysis was performed. For pts with t(11;14) or High BCL2, the median PFS was not reached in the Ven arm vs 9.9 mo in Pbo (HR=0.26, 95% CI: 0.14-0.48, p<0.001; Table 1). Higher overall response (ORR, 88% vs 70%), very good partial response or better (≥VGPR, 73% vs 33%), and complete response or better (≥CR, 42% vs 3%) rates were observed in the Ven vs Pbo arm (Table 2). Minimal residual disease negativity (MRD-, 10-5) rate was also higher for t(11;14) or High BCL2 pts in the Ven vs Pbo arm (19% vs 0%). Median overall survival (OS) was not reached in either arm but was similar between treatment arms for the combined group with t(11;14) or High BCL2 pts (HR=0.92, 95% CI=0.39-2.16, p=0.85). In contrast, in the t(11;14) negative and Low BCL2 pts, OS favored Pbo (HR=3.13, 95% CI=1.2-8.13, p=0.019; Table 1). Conclusions: Adding Ven to Bd demonstrates significant efficacy in pts with RRMM harboring either t(11;14) or tumor cells expressing high levels of BCL2. The benefit-risk profile appears to be favorable in these subsets of pts and additional studies to gain further safety and efficacy information are warranted. Disclosures Harrison: GSK: Consultancy, Research Funding; Novartis: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; AbbVie: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: investigator on studies, Research Funding; Celgene: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Amgen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Janssen Cilag: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Takeda: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding. Cavo:celgene: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: travel accommodations, Speakers Bureau; sanofi: Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; novartis: Honoraria; takeda: Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; amgen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; AbbVie: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees; janssen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: travel accommodations, Speakers Bureau; bms: Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau. De La Rubia:AMGEN: Consultancy; Takeda: Consultancy; AbbVie: Consultancy; Janssen: Consultancy; Celgene Corporation: Consultancy. Popat:Celgene Corporation: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: travel, accommodations, expenses; Janssen: Honoraria, Other: travel support to meetings; GSK: Consultancy, Honoraria; AbbVie: Consultancy, Membership on an entity's Board of Directors or advisory committees; Takeda: Honoraria, Other: travel, accommodations, expenses. Gasparetto:Janssen: Consultancy, Honoraria, Other: Travel, accommodations, or other expenses paid or reimbursed ; BMS: Consultancy, Honoraria, Other: Travel, accommodations, or other expenses paid or reimbursed ; Celgene: Consultancy, Honoraria, Other: Travel, accommodations, or other expenses paid or reimbursed . Hungria:Celgene: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Abbvie: Consultancy, Membership on an entity's Board of Directors or advisory committees; Janssen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Takeda: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; BMS: Consultancy, Honoraria, Speakers Bureau; Amgen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Abbvie: Consultancy, Membership on an entity's Board of Directors or advisory committees; Celgene: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Janssen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; BMS: Consultancy, Honoraria, Speakers Bureau; Takeda: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Amgen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau. Salwender:Amgen: Honoraria, Other: Travel or accommodations; Bristol-Myers Squibb: Honoraria, Other: Travel or accommodations; Janssen Cilag: Honoraria, Other: Travel or accommodations; Sanofi: Honoraria, Other: Travel or accommodations; Celgene: Honoraria, Other: Travel or accommodations; AbbVie: Honoraria; Takeda: Honoraria, Other: Travel or accommodations. Suzuki:Ono: Research Funding; BMS: Honoraria, Research Funding; Takeda: Honoraria; Janssen: Honoraria; Celgene: Honoraria. Moreau:Celgene: Consultancy, Honoraria; Janssen: Consultancy, Honoraria; Amgen: Consultancy, Honoraria; Takeda: Consultancy, Honoraria; AbbVie: Consultancy, Honoraria. Spencer:AbbVie: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Celgene: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau; Secura Bio: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees; Specialised Therapeutics Australia: Consultancy, Honoraria; Takeda: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau; Servier: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees; Sanofi: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees; Haemalogix: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees; Janssen Oncology: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau; Amgen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding. O'Dwyer:Janssen: Membership on an entity's Board of Directors or advisory committees, Research Funding; AbbVie: Consultancy; GlycoMimetics Inc: Research Funding; BMS: Research Funding; Onkimmune: Equity Ownership, Membership on an entity's Board of Directors or advisory committees, Research Funding. Garg:Janssen: Honoraria; Novartis, Janssen: Research Funding; Janssen, Takeda, Novartis: Other: Travel expenses. Punnoose:Roche: Other: Stock/stock options; Genentech, Inc.: Employment. Jalaluddin:AbbVie: Employment, Other: Stock/stock options. Jia:AbbVie: Employment, Other: Stock/stock options. Yang:AbbVie: Employment, Other: Stock/stock options. Sun:AbbVie: Employment, Other: Stock/stock options. Ward:AbbVie: Employment, Other: Stock/stock options. Maciag:AbbVie: Employment, Other: Stock/stock options. Ross:AbbVie: Employment, Other: Stock/stock options. Kumar:Takeda: Research Funding; Celgene: Consultancy, Research Funding; Janssen: Consultancy, Research Funding. OffLabel Disclosure: Venetoclax is a BCL-2 inhibitor that is FDA-approved in some indications. This presentation will focus on venetoclax for treatment of multiple myeloma, which is not an approved indication.
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Goodwin, Jenny, and Pamela Kent. "The incentives of Australian companies to utilize executive stock option plans." Corporate Ownership and Control 1, no. 2 (2003): 137–49. http://dx.doi.org/10.22495/cocv1i2p11.
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This study investigates the firm specific characteristics which provide ex ante incentives to Australian companies to utilize an executive stock option (ESO) plan. We hypothesize that the remuneration of the Chief Executive Officer, the firm’s investment opportunity set, the level of leverage and the degree of international diversification of the firm are related to the firm’s utilization of an ESO plan. Using a sample of 378 firms drawn from the largest 500 firms in Australia, we find that the results support our hypotheses, with the exception of the level of firm leverage.
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Bray, S. G., D. E. Allen, B. P. Harms, D. J. Reid, G. W. Fraser, R. C. Dalal, D. Walsh, D. G. Phelps, and R. Gunther. "Is land condition a useful indicator of soil organic carbon stock in Australia’s northern grazing land?" Rangeland Journal 38, no. 3 (2016): 229. http://dx.doi.org/10.1071/rj15097.
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The grazing lands of northern Australia contain a substantial soil organic carbon (SOC) stock due to the large land area. Manipulating SOC stocks through grazing management has been presented as an option to offset national greenhouse gas emissions from agriculture and other industries. However, research into the response of SOC stocks to a range of management activities has variously shown positive, negative or negligible change. This uncertainty in predicting change in SOC stocks represents high project risk for government and industry in relation to SOC sequestration programs. In this paper, we seek to address the uncertainty in SOC stock prediction by assessing relationships between SOC stocks and grazing land condition indicators. We reviewed the literature to identify land condition indicators for analysis and tested relationships between identified land condition indicators and SOC stock using data from a paired-site sampling experiment (10 sites). We subsequently collated SOC stock datasets at two scales (quadrat and paddock) from across northern Australia (329 sites) to compare with the findings of the paired-site sampling experiment with the aim of identifying the land condition indicators that had the strongest relationship with SOC stock. The land condition indicators most closely correlated with SOC stocks across datasets and analysis scales were tree basal area, tree canopy cover, ground cover, pasture biomass and the density of perennial grass tussocks. In combination with soil type, these indicators accounted for up to 42% of the variation in the residuals after climate effects were removed. However, we found that responses often interacted with soil type, adding complexity and increasing the uncertainty associated with predicting SOC stock change at any particular location. We recommend that caution be exercised when considering SOC offset projects in northern Australian grazing lands due to the risk of incorrectly predicting changes in SOC stocks with change in land condition indicators and management activities for a particular paddock or property. Despite the uncertainty for generating SOC sequestration income, undertaking management activities to improve land condition is likely to have desirable complementary benefits such as improving productivity and profitability as well as reducing adverse environmental impact.
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Brinkø, Rikke, Susanne Balslev Nielsen, and Juriaan van Meel. "Access over ownership – a typology of shared space." Facilities 33, no. 11/12 (August 3, 2015): 736–51. http://dx.doi.org/10.1108/f-11-2014-0094.
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Purpose – This paper aims to explore shared use of space and facilities as a concept, and present and illustrate the use of a typology to help classify and describe the different options for sharing space and facilities within buildings for optimised use of a building portfolio. Design/methodology/approach – The content presented is based on a cross-sectional study with an inductive approach. The results are based partly on secondary data in the form of a literature review and a mapping of 20 examples from Europe, USA and Australia, and partly on primary data from observations and interviews with key actors from two cases in Denmark and an illustration case from Ireland. Findings – The typology classifies and describes four archetypes of sharing between different people, building owners and organisations, to be used when discussing, planning, establishing and evaluating new and existing shared spaces. Research limitations/implications – The typology is the result of a first exploration of shared use of facilities and does not claim to be fully comprehensive or final. Practical implications – The typology is intended for both researchers and practitioners, and aims at increasing the understanding of sharing as a way to minimise the need for building new by better utilisation of the existing building stock. Originality/value – Shared space and facilities is a relatively new topic with not much research undertaken. This typology provides a language for discussing shared spaces and a base for further developing the research field.
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Williams, Ashley J., L. Richard Little, and Gavin A. Begg. "Balancing indigenous and non-indigenous commercial objectives in a coral reef finfish fishery." ICES Journal of Marine Science 68, no. 5 (May 1, 2011): 834–47. http://dx.doi.org/10.1093/icesjms/fsr034.
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Abstract Williams, A. J., Little, L. R., and Begg, G. A. 2011. Balancing indigenous and non-indigenous commercial objectives in a coral reef finfish fishery. – ICES Journal of Marine Science, 68: 834–847. Indigenous participation in commercial fisheries is poorly established in Australia, except in Torres Strait where indigenous and non-indigenous commercial fishers participate in the Torres Strait Finfish Fishery (TSFF). TSFF stakeholders helped identify specific objectives and alternative management strategies for the fishery at a time when new management strategies were under consideration. A metapopulation and fishing simulation model was used to evaluate alternative management strategies related to harvest and conservation of coral trout (Plectropomus spp.), the main target species. Stakeholders identified objectives relating to conservation of unfished populations, maintenance of harvestable stock, and economic performance. In terms of management options, spatial closures decreased the prospects of meeting nearly all stakeholder objectives. A seasonal closure and larger minimum capture size increased the probability of meeting conservation and harvest objectives, but decreased the probability of meeting most economic objectives for both sectors. Increasing fishing effort increased harvest but decreased the catch rates for both sectors, so had varied effects on the probability of achieving harvest objectives. The research provides a case study of productive engagement with indigenous and non-indigenous stakeholders to address fisheries management needs and provides a framework for impartial evaluation of performance of alternative management strategies against stakeholder objectives.
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Ren, Siewan, Anna Wright, and Anne Wyatt. "Stock option use by Australian IPOs." Journal of Contemporary Accounting & Economics 8, no. 1 (June 2012): 1–22. http://dx.doi.org/10.1016/j.jcae.2012.03.003.
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Harris, John. "Is LNG the panacea for Australia's natural gas?" APPEA Journal 50, no. 2 (2010): 713. http://dx.doi.org/10.1071/aj09077.
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Australia already has abundant natural gas reserves. To what extent will LNG exports grow? What is the potential for future conventional gas discoveries? Is there a potential round of additional CBM-sourced LNG projects? Could shale gas contribute to supply? There are already a significant number of proposed LNG projects in Australia. How many more projects might emerge to add to the current tally? In the longer term, Australia has the potential to surpass Qatar as the world’s leading LNG exporter but which markets can help Australia realise that potential? With growing Asian demand for LNG, and buyers historically accustomed to oil-linked long term contracts, the prospects for LNG appear good. But are they? To what extent can growth in Asian gas demand absorb Australian LNG, which itself has to compete with other LNG projects? If Asian demand is satiated, what are the alternative markets? North America provides another potential outlet for Australian LNG exports, but how do the project economics stack up relative to Asia? Does South America offer market opportunities and if so can countries there absorb a meaningful volume of Australian LNG? A detailed consideration of project costs and the outlook for gas prices in Asia and the Americas can help shed light on this question. It can also set Australia’s LNG projects in context relative to its competitors. If LNG is not the panacea for Australia’s natural gas, will alternative monetisation options emerge, and what might they be?
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Bodhanwala, Shernaz, and Ruzbeh Bodhanwala. "Relationship between sustainable and responsible investing and returns: a global evidence." Social Responsibility Journal 16, no. 4 (June 15, 2019): 579–94. http://dx.doi.org/10.1108/srj-12-2018-0332.
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Purpose The purpose of this study is to examine whether sustainable and responsible investing (SRI) outperforms the benchmark index investing across different time frames globally. Design/methodology/approach Based on the systematic weighted environmental, social and governance (ESG) ratings compiled by Thomson Reuters Asset4, the authors assess the stock market performance and risk of highly compliant firms portfolio in seven different countries; grouped as developed and developing nations over different time frames by adopting the Jensen’s alpha model (CAPM) and the Fama and French three-factor model. Findings The study finds that SRI portfolios significantly underperform their benchmark index, in case of, the developing nations, however, enjoy a significantly lower risk. This is contrary to the findings in case of developed nations, where the US SRI portfolio has significantly outperformed the benchmark index and the UK and Australia SRI portfolios have performed in line with the benchmark index. Finally, the study discusses results and implications for regulators, practitioners and investors’ who believe in the SRI investing. Research limitations/implications This study provides empirical support for the practitioners, policymakers and investors emphasizing that in the case of developed nations SRI investments generate a significant excess return or at the best perform in line with the broader market index. However, in the case of developing nations, very few firms are consistently rated on ESG parameters. This provides lesser options for investors in developing nations to apply the “impact first” philosophy of investment. The investor’s community and regulators need to make a serious effort in promoting firms to take up sustainability effort seriously. Originality/value The unique contribution of this study is that it considers a wider definition of the term “sustainability” and examines the performance of SRI investment in developed vs developing countries. This is one of the few studies at the global level, which highlights whether sustainable investing generates abnormal risk-adjusted returns for the investors.
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Niblock, Scott J., and Elisabeth Sinnewe. "Are covered calls the right option for Australian investors?" Studies in Economics and Finance 35, no. 2 (June 4, 2018): 222–43. http://dx.doi.org/10.1108/sef-07-2016-0164.
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Purpose The purpose of this paper is to examine whether superior risk-adjusted returns can be generated using monthly covered call option strategies in large capitalized Australian equity portfolios and across varying market volatility conditions. Design/methodology/approach The authors construct monthly in-the-money (ITM) and out-of-the-money (OTM) S&P/ASX 20 covered call portfolios from 2010 to 2015 and use standard and alternative performance measures. An assessment of variable levels of market volatility on risk-adjusted return performance is also carried out using the spread between implied and realized volatility indexes. Findings The results of this paper show that covered call writing produces similar nominal returns at lower risk when compared against the standalone buy-and-hold portfolio. Both standard and alternative performance measures (with the exception of the upside potential ratio) demonstrate that covered call portfolios produce superior risk-adjusted returns, particularly when written deeper OTM. The 36-month rolling regressions also reveal that deeper OTM portfolios deliver greater risk-adjusted returns in the majority of the sub-periods investigated. This paper also establishes that volatility spread variation may be a driver of performance for covered call writing in Australia. Originality/value The authors suggest that deeper OTM covered call strategies based on large capitalized portfolios create value for investors/fund managers in the Australian stock market and can be executed in volatile market conditions. Such strategies are particularly useful for those seeking market neutral asset allocation and less risk exposure in volatile market environments.
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Konstandatos, Otto. "Fair-value analytical valuation of reset executive stock options consistent with IFRS9 requirements." Annals of Actuarial Science 14, no. 1 (January 23, 2020): 188–218. http://dx.doi.org/10.1017/s1748499519000125.
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AbstractExecutive stock options (ESOs) are widely used to reward employees and represent major items of corporate liability. The International Accounting Standards Board IFRS9 financial reporting standard which came into full effect on 1-Jan 2018, along with its Australian implementation AASB9, requires public corporations to report their fair-value cost in financial statements. Reset ESOs are typically issued to re-incentivise employees by allowing the option to be cancelled and re-issued with a lower exercise price or later maturity. We produce a novel analytical Reset ESO valuation consistent with the IFRS9 financial reporting standard incorporating the simultaneous resetting of vesting period, exercise window, reset level and maturity. We allow for voluntary and involuntary exercise. Our analytical result is expressed solely in terms of standardised European binary power option instruments. Using the multi-state mortality model of Hariyanto (2014, Mortality and disability modelling with an application to pricing a reverse mortgage contract, PhD thesis, University of Melbourne), we estimate longitudinal disability and death transition probabilities from cross-sectional data. We determine survival functions for pre-vesting forfeiture or post-vesting involuntary exercise for use with weighted portfolios of our formulae to illustrate the effect of survival on the fair value. We examine the IFRS9 method of valuation using expected time to option exercise and demonstrate a consistent overestimation of fair value of up to 27% for senior executives.
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Hernando, Diego, Ruiyang Zhao, Qing Yuan, Mounes Aliyari Ghasabeh, Stefan Ruschke, Xinran Miao, Dimitrios C. Karampinos, et al. "Multi-Center, Multi-Vendor Reproducibility and Calibration of MRI-Based R2* for Liver Iron Quantification." Blood 138, Supplement 1 (November 5, 2021): 2010. http://dx.doi.org/10.1182/blood-2021-148803.
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Abstract Introduction: Excessive accumulation of iron is caused by a variety of conditions, including hereditary hemochromatosis and transfusional hemosiderosis. If untreated, iron overload can lead to damage in those organs where iron accumulates. Therefore, accurate and reproducible evaluation of body iron stores is needed to guide diagnosis, grading, and treatment monitoring of iron overload. While serum ferritin is the simplest means to assess body iron, it is also an acute phase reactant and therefore is not a reliable biomarker of body iron. Liver iron concentration (LIC) is directly and linearly related to total body iron stores. As such, LIC is widely recognized as a useful surrogate biomarker for the evaluation of iron overload. Liver biopsy is limited by its invasive nature and is contraindicated in many patients (eg. thrombocytopenia) due to bleeding risk. Magnetic resonance imaging (MRI) is a standard of care tool to measure LIC. Arguably the most practical method is R2* MRI due to its speed and ease of use, but the cross-vendor reproducibility of R2*-based LIC estimation remains unknown. Therefore, we evaluated the reproducibility and calibration of R2*-based LIC measurement via a single-breath-hold, confounder-corrected R2*-MRI at both 1.5T and 3T, through a multi-center, multi-vendor study. Methods: Four centers (University of Wisconsin-Madison, University of Texas-Southwestern, Johns Hopkins University, and Stanford University) using MRI scanners of different vendors (GE, Philips, and Siemens) participated in this HIPAA-compliant IRB-approved prospective cross-sectional study. This study recruited subjects with known or suspected iron overload from a variety of etiologies, including hereditary hemochromatosis, transfusional hemosiderosis (due to non-malignant or malignant conditions), and chronic liver disease. Subjects with were recruited for same day multiecho gradient-echo MRI for R2* mapping at both 1.5T and 3T (UW, UTSW, Stanford: 3.0T; JHU: 2.89T). R2* maps were reconstructed from the raw multiecho images and analyzed at a single center. Spin-echo MRI were also performed at 1.5T according to a standardized protocol (FerriScan, Resonance Health, Australia) and processed by a commercial algorithm to obtain FDA-approved reference standard LIC estimates. R2*-vs.-LIC calibrations were generated across centers and field strengths using linear regression and compared using F-tests. A predicted 2.89T calibration was interpolated from the 1.5T and 3.0T calibrations, and compared to the measured (JHU) calibration. Receiver operating characteristic (ROC) curve analysis was performed to determine the diagnostic accuracy of R2* MRI for detection of clinically relevant LIC thresholds. Results: A total of 200 subjects were recruited and successfully scanned for this study. We confirmed a linear relationship between R2* and LIC. All calibrations within the same field strength (see Figure 1) were highly reproducible showing no statistically significant center-specific differences (F > 3.0461). Pooled calibrations for 1.5T, 2.89T, and 3.0T were generated. At either field strength and for each of the LIC thresholds under consideration (1.8, 3.2, 7.0, 15.0 mg/g), estimated areas under the ROC curve (AUCs) of 0.98 or higher were observed. Discussion and Conclusions: In conclusion, confounder-corrected R2* MRI enables accurate and reproducible quantification of liver iron overload, over clinically relevant ranges of LIC. The data generated in this study provide the necessary calibrations for broad dissemination of R2*-based LIC quantification. Figure 1 Figure 1. Disclosures Hernando: Calimetrix: Current holder of individual stocks in a privately-held company. Pedrosa: Merck: Honoraria; Bayer Healthcare: Honoraria; Health Tech International: Current holder of stock options in a privately-held company. Vasanawala: HeartVista: Current holder of individual stocks in a privately-held company; InkSpace: Current holder of individual stocks in a privately-held company; Arterys: Current holder of individual stocks in a privately-held company. Reeder: Bayer: Research Funding; Pfizer: Research Funding; Calimetrix, LLC: Current holder of individual stocks in a privately-held company; Reveal Pharmaceuticals: Current holder of individual stocks in a privately-held company; Elucent Medical: Current holder of individual stocks in a privately-held company; Cellectar Biosciences: Current holder of individual stocks in a privately-held company; HeartVista: Current holder of individual stocks in a privately-held company.
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McGrath, S. R., R. Behrendt, M. A. Friend, and A. D. Moore. "Utilising dual-purpose crops effectively to increase profit and manage risk in meat production systems." Animal Production Science 61, no. 11 (2021): 1049. http://dx.doi.org/10.1071/an20495.
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Dual-purpose cropping (sowing crops with the intention of both grazing them during vegetative growth and harvesting grain thereafter) has become a widespread farming practice in southern Australia. This synopsis paper integrates research from a multi-institutional research project conducted at three nodes located near Hamilton (south-western Victoria), Wagga Wagga (southern NSW) and Canberra (ACT), and sets out 11 principles for the effective utilisation of dual-purpose crops in meat production systems to increase profit and manage risk. Dual-purpose crops can be used to overcome feed quality gaps in late summer–autumn or feed quantity gaps in late autumn/winter. They provide large quantities of high-quality forages for grazing in summer, autumn and winter and can provide a substantial contribution to the annual number of grazing days on a farm. Utilisation of the high-quality dry matter provided by dual-purpose crops is most effective when directed at young growing stock for sale or future reproduction rather than reproducing adult ewes. For example, sale weight of yearlings per ewe was increased by 16% in systems at the Canberra node when dual-purpose crops were prioritised for grazing by weaners. Wool production was also increased in systems that included grazing of dual-purpose crops. Grazing crops in winter does not necessarily reduce supplementary feeding costs for winter or spring lambing. Modelling suggests that inclusion of dual-purpose crops does not substantially change the optimum time of lambing for sheep meat systems. Financial analysis of the experimental data from the Canberra node showed that although cash expenses per hectare were increased in the crop-grazing systems, the overall profitability of those systems over the life of the experiment was greater by AU$207/ha.year than that of the pasture-only system. Factors driving improved profitability included income from grain, higher income from meat and wool, and lower supplementary feeding costs. However, increasing the area sown to crop from 10% to 30% of the farm area in this Southern Tablelands system appeared to increase risk. In south-western Victoria, spring-sown canola carried risk similar to or less than other options assessed to achieve ewe-lamb mating weight. It is likely that at least part of the reduction in risk occurs through the diversification in income from the canola produced as part of the system. It was concluded that the grazing of cereal and canola crops for livestock production can be profitable and assist in managing risk.
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Qu, Xin, Majella Percy, Jenny Stewart, and Fang Hu. "Executive stock option vesting conditions, corporate governance and CEO attributes: evidence from Australia." Accounting & Finance 58, no. 2 (July 29, 2016): 503–33. http://dx.doi.org/10.1111/acfi.12223.
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Canil, Jean M., and Bruce A. Rosser. "Executive stock options: Preliminary Australian evidence of shareholder wealth effects of pre-effort contracting." Corporate Ownership and Control 2, no. 3 (2005): 94–105. http://dx.doi.org/10.22495/cocv2i3p10.
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We document a structure of pre-effort conditions associated with ESOPs. Since we can observe shareholder returns at award we infer incentive effects in a setting where premium and discounted executive stock options are regularly awarded. Discounted (premium) awards are associated with the highest (lowest) exercise rates, implying a successful incentive (disincentive) effect. Exercise restrictions (comprising hurdles and vesting restrictions) necessarily lower exercise rates, but may be preferred in combination with a discounted or premium award. Typically, a discount choice is associated with hurdles but not vesting restrictions. Empirically, shareholders benefit most from regular awards which are discounted and do not have hurdle price restrictions. Shareholders also benefit from hurdle provisions in irregular awards which may expose shareholders to CEO opportunism.
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Duppati, Geeta, and Mengying Zhu. "Oil prices changes and volatility in sector stock returns: Evidence from Australia, New Zealand, China, Germany and Norway." Corporate Ownership and Control 13, no. 2 (2016): 351–70. http://dx.doi.org/10.22495/cocv13i2clp4.
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The paper examines the exposure of sectoral stock returns to oil price changes in Australia, China, Germany, New Zealand and Norway over the period 2000-2015 using weekly data drawn from DataStream. The issue of volatility has important implications for the theory of finance and as is well-known accurate volatility forecasts are important in a variety of settings including option and other derivatives pricing, portfolio and risk management (e.g. in the calculation of hedge ratios and Value-at-Risk measures), and trading strategies (David and Ruiz, 2009). This study adopts GARCH and EGARCH to understand the relationship between the returns and volatility. The findings using GARCH (EGARCH) models suggests that in the case of Germany eight (nine) out of ten sectors returns can be explained by the volatility of past oil price in Germany, while in the case of Australia, six (seven) out of ten sector returns are sensitive to the oil price changes with the exception of Industrials, Consumer Goods, Health care and Utilities. While in China and New Zealand five sectors are found sensitive to oil price changes and three sectors in Norway, namely Oil & Gas, Consumer Services and Financials. Secondly, this paper also investigated the exposure of the stock returns to oil price changes using market index data as a proxy using GARCH or EGARCH model. The results indicated that the stock returns are sensitive to the oil price changes and have leverage effects for all the five countries. Further, the findings also suggests that sector with more constituents is likely to have leverage effects and vice versa. The results have implications to market participants to make informed decisions about a better portfolio diversification for minimizing risk and adding value to the stocks.
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Widiyanti, Novi Wulandari. "KARATERISTIK DAN MEKANISME PERDAGANGAN CONTRACT FOR DIFFERENCE (CFD) SEBAGAI ALTERNATIF INVESTASI KEUANGAN (Studi Kasus Pada Pasar Derivatif di Australia)." JURNAL AKUNTANSI UNIVERSITAS JEMBER 8, no. 1 (March 31, 2015): 25. http://dx.doi.org/10.19184/jauj.v8i1.1220.
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The paper exploresthe nature of CFDs as a derivative and CFDs as hedging instrumentin derivatif markets in Australia. It argues that CFDis leveraged instrument, which means they offer the potential to make a higher return from a smaller initial investment relative to the total position value. Using CFD, we can obtain full exposure to a share or commodity for a fraction of the price of buying the underlying asset. The higher percentage return from the CFD demonstrates how leverage can work.
The writer presents two parts in describing CFD’s nature and trading mechanism which are:the nature of the CFDs, which include CFDs’ characteristics and how they are traded. This part will focus on equity CFDs which underlying instrument is stocks. The second part will be an application of delta neutral hedging of long stock position by using and option compare to CFDs.
Keywords: derivatif instrument, CFD, underlying asset, hedging, long position, short position
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Bray, Steven, Dionne Walsh, David Phelps, Joe Rolfe, Kiri Broad, Giselle Whish, and Michael Quirk. "Climate Clever Beef: options to improve business performance and reduce greenhouse gas emissions in northern Australia." Rangeland Journal 38, no. 3 (2016): 207. http://dx.doi.org/10.1071/rj15124.
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The Rangeland Journal – Climate Clever Beef special issue examines options for the beef industry in northern Australia to contribute to the reduction in global greenhouse gas (GHG) emissions and to engage in the carbon economy. Relative to its gross value (A$5 billion), the northern beef industry is responsible for a sizable proportion of national reportable GHG emissions (8–10%) through enteric methane, savanna burning, vegetation clearing and land degradation. The industry occupies large areas of land and has the potential to impact the carbon cycle by sequestering carbon or reducing carbon loss. Furthermore, much of the industry is currently not achieving its productivity potential, which suggests that there are opportunities to improve the emissions intensity of beef production. Improving the industry’s GHG emissions performance is important for its environmental reputation and may benefit individual businesses through improved production efficiency and revenue from the carbon economy. The Climate Clever Beef initiative collaborated with beef businesses in six regions across northern Australia to better understand the links between GHG emissions and carbon stocks, land condition, herd productivity and profitability. The current performance of businesses was measured and alternate management options were identified and evaluated. Opportunities to participate in the carbon economy through the Australian Government’s Emissions Reduction Fund (ERF) were also assessed. The initiative achieved significant producer engagement and collaboration resulting in practice change by 78 people from 35 businesses, managing more than 1 272 000 ha and 132 000 cattle. Carbon farming opportunities were identified that could improve both business performance and emissions intensity. However, these opportunities were not without significant risks, trade-offs and limitations particularly in relation to business scale, and uncertainty in carbon price and the response of soil and vegetation carbon sequestration to management. This paper discusses opportunities for reducing emissions, improving emission intensity and carbon sequestration, and outlines the approach taken to achieve beef business engagement and practice change. The paper concludes with some considerations for policy makers.
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Niblock, Scott James. "Flight of the Condors: Evidence on the Performance of Condor Option Spreads in Australia." Applied Finance Letters 6, no. 01 (December 6, 2017): 38–53. http://dx.doi.org/10.24135/afl.v6i01.69.
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This paper examines whether superior nominal and risk-adjusted returns can be generated using condor option spread strategies on a large capitalized Australian stock. Monthly Commonwealth Bank of Australia Ltd (CBA) condor option spreads are constructed from 2012 to 2015 and their returns established. Standard and alternative measures are used to determine the nominal and risk-adjusted performance of the spreads. The results show that the short put condor spread produces superior nominal and risk-adjusted returns, but seemingly underperformed when the upside potential ratio was taken into consideration. The long iron condor spread also offers reasonable returns across both performance metrics. On the other hand, the short call condor, long call condor, short iron condor and long put condor spreads did not perform as well on a nominal and risk-adjusted return basis. The results suggest that constructing spreads on the foundation of volatility preferences could be a driver of performance for condor option spreads strategies. For instance, short volatility condor spreads with negatively skewed return distribution shapes appear to add value, while long volatility condor spreads with positively skewed return distribution shapes seem to be less attractive over the sample period. Overall, condor option spreads demonstrate high risk-return profiles, offer versatility in their construction and intended pay-off outcomes, create value in some instances and can be executed across varying market conditions. It is suggested that risk averse investors best avoid condor option spreads, while those with above average risk tolerances may be well suited to the strategies, particularly short volatility-driven condor spreads.
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Doran-Browne, Natalie A., John Ive, Phillip Graham, and Richard J. Eckard. "Carbon-neutral wool farming in south-eastern Australia." Animal Production Science 56, no. 3 (2016): 417. http://dx.doi.org/10.1071/an15541.
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Ruminant livestock production generates higher levels of greenhouse gas emissions (GHGE) compared with other types of farming. Therefore, it is desirable to reduce or offset those emissions where possible. Although mitigation options exist that reduce ruminant GHGE through the use of feed management, flock structure or breeding management, these options only reduce the existing emissions by up to 30% whereas planting trees and subsequent carbon sequestration in trees and soil has the potential for livestock emissions to be offset in their entirety. Trees can introduce additional co-benefits that may increase production such as reduced salinity and therefore increased pasture production, shelter for animals or reduced erosion. Trees will also use more water and compete with pastures for water and light. Therefore, careful planning is required to locate trees where the co-benefits can be maximised instead of any negative trade-offs. This study analysed the carbon balance of a wool case study farm, Talaheni, in south-eastern Australia to determine if the farm was carbon neutral. The Australian National Greenhouse Gas Inventory was used to calculate GHGE and carbon stocks, with national emissions factors used where available, and otherwise figures from the IPCC methodology being used. Sources of GHGE were from livestock, energy and fuel, and carbon stocks were present in the trees and soil. The results showed that from when the farm was purchased in 1980–2012 the farm had sequestered 11 times more carbon dioxide equivalents (CO2e) in trees and soil than was produced by livestock and energy. Between 1980 and 2012 a total of 31 100 t CO2e were sequestered with 19 300 and 11 800 t CO2e in trees and soil, respectively, whereas farm emissions totalled 2800 t CO2e. There was a sufficient increase in soil carbon stocks alone to offset all GHGE at the study site. This study demonstrated that there are substantial gains to be made in soil carbon stocks where initial soils are eroded and degraded and there is the opportunity to increase soil carbon either through planting trees or introducing perennial pastures to store more carbon under pastures. Further research would be beneficial on the carbon-neutral potential of farms in more fertile, high-rainfall areas. These areas typically have higher stocking rates than the present study and would require higher levels of carbon stocks for the farm to be carbon neutral.
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Samelson-Jones, Ben J., Spencer K. Sullivan, John E. J. Rasko, Adam Giermasz, Lindsey A. George, Jonathan M. Ducore, Jerome M. Teitel, et al. "Follow-up of More Than 5 Years in a Cohort of Patients with Hemophilia B Treated with Fidanacogene Elaparvovec Adeno-Associated Virus Gene Therapy." Blood 138, Supplement 1 (November 5, 2021): 3975. http://dx.doi.org/10.1182/blood-2021-150541.
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Abstract Fifteen patients with moderately severe to severe hemophilia B (factor IX [FIX] activity ≤2%) were treated with fidanacogene elaparvovec at a dose of 5e11 vg/kg as part of a phase 1/2a study. The study was 52 weeks in duration, after which patients were eligible to enroll in the long-term follow-up (LTFU) study of up to 5 years. All 15 patients completed the phase 1/2a study, and 14 patients were subsequently enrolled in the LTFU study. At the time of the data cut (December 2020), 13 patients were enrolled in the LTFU study, with follow-up ranging from >2.5 years to >5 years following vector administration. Over this period of time, fidanacogene elaparvovec remained generally well tolerated. As reported previously, 3 patients were treated with corticosteroids within the first 6 months of the phase 1/2a study. No patients have required treatment or re-treatment with corticosteroids in the LTFU study. There were no serious adverse events (SAEs) in the phase 1/2a study, and 3 patients reported SAEs in the LTFU study, none of which were considered treatment related. No patient developed an inhibitor or had a thrombotic event. No patients have developed hepatic masses or significant elevations in alpha-fetoprotein (AFP). Annual liver ultrasounds revealed only hepatic steatosis in one patient. Mean FIX activity levels by year remain in the mild hemophilia severity range: 22.8%, year 1 (n=15); 25.4%, year 2 (n=14); 22.9%, year 3 (n=14); 24.9%, year 4 (n=9); and 19.8%, year 5 (n=7) when evaluated centrally using the ACTIN/FSL one-stage assay. These levels have been associated with mean annualized bleeding rates ranging from 0-0.9 over the course of follow-up, and no patients have resumed FIX prophylaxis. Four patients have undergone 6 surgical procedures during the LTFU study, 4 elective and 2 emergent. There were no bleeding complications with these procedures, and the 2 emergent procedures (appendectomy and lumbar discectomy) were performed without the need of additional FIX. Overall, this represents the largest cohort of hemophilia B patients with a duration of follow-up up to 5 years following treatment with an adeno-associated virus gene therapy expressing a highly active variant of FIX. Fidanacogene elaparvovec remains generally well tolerated over a period up to 5 years postinfusion. While encouraging, more long-term data in a larger cohort of patients are needed to further characterize the safety and durability of fidanacogene elaparvovec, which is under way in an ongoing phase 3 study. Disclosures Samelson-Jones: Pfizer: Consultancy, Research Funding; Spark: Research Funding. Sullivan: Genentech: Membership on an entity's Board of Directors or advisory committees; Bayer: Membership on an entity's Board of Directors or advisory committees; Pfizer Inc.: Membership on an entity's Board of Directors or advisory committees; Biomarin: Membership on an entity's Board of Directors or advisory committees; Octapharma: Membership on an entity's Board of Directors or advisory committees. Rasko: Imago: Consultancy; Cynata: Honoraria, Speakers Bureau; Gene Technology Technical Advisory Board: Membership on an entity's Board of Directors or advisory committees; NHMRC Mitochondrial Donation Expert Working Committee: Membership on an entity's Board of Directors or advisory committees; Australian Cancer Research: Membership on an entity's Board of Directors or advisory committees; Cure the Future Foundation: Membership on an entity's Board of Directors or advisory committees; FSHD Global Research Foundation: Membership on an entity's Board of Directors or advisory committees; Australian Government: Membership on an entity's Board of Directors or advisory committees; Gilead: Honoraria, Speakers Bureau; Novartis: Honoraria, Speakers Bureau; Pfizer Inc: Honoraria, Speakers Bureau; Glaxo-Smith-Kline: Honoraria, Speakers Bureau; Spark: Honoraria, Speakers Bureau; Takeda: Honoraria, Speakers Bureau; bluebird bio: Honoraria, Speakers Bureau; Genea: Current equity holder in publicly-traded company; Celgene: Honoraria, Speakers Bureau. Giermasz: BioMarin: Consultancy, Research Funding; Genentech/Roche: Consultancy, Research Funding, Speakers Bureau; Pfizer: Consultancy; Bayer: Consultancy; ATHN: Consultancy; NovoNordisk: Consultancy; UniQure: Consultancy, Research Funding; Sanofi Genzyme: Consultancy; Bioverativ/Sanofi: Consultancy, Research Funding, Speakers Bureau; Sangamo Therapeutics,: Research Funding. George: CSL Behring: Consultancy; Bayer: Consultancy; Avrobio: Other: Data Safety Monitoring Committee . Ducore: Octapharma: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees; Shire: Consultancy, Honoraria; Bayer: Consultancy, Honoraria, Speakers Bureau; HEMA Biologics: Consultancy, Honoraria. Teitel: Pfizer: Consultancy, Research Funding; Spark: Research Funding; Bayer: Consultancy, Research Funding; Takeda: Consultancy, Research Funding; Novo Nordisk: Consultancy; Octapharma: Consultancy; CSL Behring: Consultancy. McGuinn: Biogen: Research Funding; Roche/Genentech: Research Funding; Shire/Baxalta: Consultancy, Research Funding; Spark: Research Funding. O'Brien: Pfizer Inc.: Current Employment, Current holder of individual stocks in a privately-held company, Current holder of stock options in a privately-held company. Winburn: Pfizer Inc.: Current Employment, Current holder of individual stocks in a privately-held company, Current holder of stock options in a privately-held company. Smith: Pfizer Inc.: Current Employment, Current holder of individual stocks in a privately-held company, Current holder of stock options in a privately-held company. Chhabra: Pfizer Inc.: Current Employment, Current holder of individual stocks in a privately-held company, Current holder of stock options in a privately-held company. Rupon: Pfizer Inc.: Current Employment, Current holder of individual stocks in a privately-held company, Current holder of stock options in a privately-held company.
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Li, Steven, and Qianqian Yang. "The relationship between implied and realized volatility: evidence from the Australian stock index option market." Review of Quantitative Finance and Accounting 32, no. 4 (September 27, 2008): 405–19. http://dx.doi.org/10.1007/s11156-008-0099-2.
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Godrich, Stephanie Louise, Flavio Macau, Katherine Kent, Johnny Lo, and Amanda Devine. "Food Supply Impacts and Solutions Associated with the COVID-19 Pandemic: A Regional Australian Case Study." International Journal of Environmental Research and Public Health 19, no. 7 (March 30, 2022): 4116. http://dx.doi.org/10.3390/ijerph19074116.
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This study aimed to explore how food supply chains were impacted by COVID-19 and identify how the region could be better prepared for future crises. An online survey was completed by 107 consumers. In-depth interviews were conducted with 27 food supply stakeholders working in food production, distribution, retail, hospitality, institutions (i.e., childcare), logistics/freight and local government. Pre-COVID-19, farmer-direct distribution options and hospitality businesses comprised a substantial proportion of local food producer businesses. During the COVID-19 pandemic, consumers favoured local food supply options, farmers collaborated, and produce usually destined for export was redirected into local markets. Critical food supply actions included keeping borders open to food freight, enhancing social capital through real-time business communication, and business flexibility. Solutions included business adaptation, for example, farmers selling produce boxes and hospitality businesses selling excess stock, COVID-safe delivery, and collaboration through digital networks. To better prepare the region for future crises, actions to support communities could include a community approach to agriculture, increasing food supply diversity, facilitating transport to aid food distribution and purchasing, and more effective messaging to discourage panic buying. Actions to support retailers could include increasing access to wholesalers through online platforms. Actions to support producers could include improving infrastructure, such as more regional distribution facilities.
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Doran-Browne, Natalie, Mark Wootton, Chris Taylor, and Richard Eckard. "Offsets required to reduce the carbon balance of sheep and beef farms through carbon sequestration in trees and soils." Animal Production Science 58, no. 9 (2018): 1648. http://dx.doi.org/10.1071/an16438.
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The sustainability of farming is important to ensure that natural resources remain available into the future. Ruminant livestock production generates more greenhouse gas emissions than other types of agricultural production and most livestock mitigation options to date have a modest greenhouse gas reduction potential (<20%). Trees and soils, by comparison, can sequester large amounts of carbon depending on the availability of land. Previous studies on carbon neutral livestock production have shown that farms with a stocking rate of 8 dry sheep equivalents (DSE)/ha can be carbon neutral or carbon positive by sequestering more carbon than is emitted from the farm. However, the carbon offsets required by farms with higher stocking rates (>20 DSE/ha) has yet to be studied in Australia. The challenge is to sequester enough carbon to offset the higher level of emissions that these higher stocked farms produce. This study calculated the carbon balance of wool, prime lamb and beef enterprises using a range of stocking rates (6–22 DSE/ha) and levels of tree cover in two agroecological zones. Emissions from livestock, energy and transport were offset by the carbon sequestered in trees and soils. Additionally, the carbon balance was calculated of a case study, Jigsaw Farms, an intensive sheep and beef farm in south-eastern Australia. The methods used to calculate emissions and carbon stocks were from the Australian National Greenhouse Gas Inventory. The majority of stocking rates were carbon positive over a 25-year period when 20% of the sheep or beef enterprises were covered with trees. This study demonstrated that substantial reductions can be made in greenhouse gas emissions through the use of carbon sequestration, particularly in trees. The results showed that from 2000 to 2014 Jigsaw Farms reduced its emissions by 48% by sequestering carbon in trees and soil. The analysis of different stocking rates and tree cover provides an important reference point for farmers, researchers and policy analysts to estimate the carbon balance of wool, prime lamb and beef enterprises based on stocking rate and the area of tree cover.
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Salahuddin, Sultan, Salman Sarwat, Umair Baig, and Mudassir Hussain. "Time-varying Stock Market Integration and Diversification Opportunities within Developed Markets Using Aggregated Data Approach." Market Forces 17, no. 1 (June 28, 2022): 59–80. http://dx.doi.org/10.51153/mf.v17i1.535.
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This study examines the time-varying feature of Developed stock markets to identify diversification opportunities. For this purpose, we sample 21 developed countries ranging from 2000-2018 from the Pacific Region, Northern Europe, Western Europe, Southern Europe, and G7, with each region consisting of a panel with one home country and other as remaining countries portfolio. We applied Panel co-integration and VECM to test the stock market integration and diversification opportunities in short and long run. Our results indicate few short and long-run diversification opportunities for international investors in the post-crisis period that are more relevant. Canada, Japan, and Italy have long-run opportunities for diversification in the G7, and only Japan has short-run opportunities for diversification. Hong Kong and Japan have short-and long-run opportunities for diversification in the Pacific region. In the Northern Europe region, we have only the short-run diversification option of the UK and Norway. In the Western European Region, Australia and Switzerland have long-term diversification. There are no long and short-run diversification opportunities in the Southern European Region in the post-crisis period.
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Ferguson, C. M., N. J. Ashbolt, and D. A. Deere. "Prioritisation of catchment management in the Sydney catchment - construction of a pathogen budget." Water Supply 4, no. 2 (April 1, 2004): 35–38. http://dx.doi.org/10.2166/ws.2004.0025.
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A methodology has been developed to apply the materials budget concept, used in sediment and nutrient studies, to construct a pathogen budget for drinking water catchments, taking into consideration pathogen origin, deposition, inactivation and movement within a catchment. These processes can be described in terms of stocks (pathogens) and flows (movement of stocks). In south-eastern Australia, the majority of pathogen loading to major tributaries was predicted to occur during and after high intensity rainfall events where in-stream resuspension was not of great relative importance. In contrast, during dry weather the transit time within the studied catchment was sufficiently long that in-stream processes became relatively important. Total pathogen unit (TPU) budgets were constructed for the parasitic protozoa Cryptosporidium and Giardia. This approach enables water utility managers to identify those catchment segments and processes that are contributing or removing the greatest load of pathogens, and thus where management options will be most effective. With improved knowledge of pathogen ecology this approach can be further refined to provide budgets of infectious pathogen units (IPU), more directed to public health risk endpoints.
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Moglia, Magnus, Grace Tjandraatmadja, and Ashok K. Sharma. "Exploring the need for rainwater tank maintenance: survey, review and simulations." Water Supply 13, no. 2 (March 1, 2013): 191–201. http://dx.doi.org/10.2166/ws.2013.021.
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Rainwater tanks are a common feature of the urban landscape in Australia and globally. In Brisbane, Australia, provision of alternative water in new homes is mandatory and to meet this requirement rainwater tanks are considered an important option. The water savings of rainwater tanks can help defer investments in supply infrastructures. An emerging concern is that there is currently no mechanism in place for making sure that the household rainwater collection systems are maintained and in a good condition. In fact, in many locations, there is growing concern about whether the condition of this asset stock is adequate. The paper presents: a synthesis of required basic water tanks maintenance tasks; a short overview of published literature on householder motivations for maintenance; a synthesis of existing information about the condition of tanks, based on literature; simulation model results identifying the relationship between frequency of inspections and the (stationary) proportion of tanks with different types of problems; and the results of a survey to identify judgements about water tank maintenance in the region by professionals and plumbers. The paper concludes that there is a need for collecting more data and that mechanisms need to be in place to ensure the ongoing condition of tanks.
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Cote, Doug W., and Tara K. McGee. "An exploration of residents’ intended wildfire evacuation responses in Mt. Lorne, Yukon, Canada." Forestry Chronicle 90, no. 04 (August 2014): 498–502. http://dx.doi.org/10.5558/tfc2014-100.
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Wildfire evacuations disrupt people’s lives, create an additional hazard for emergency responders and residents, and are expensive to execute. Alternatives to evacuation are used in Australia and a few jurisdictions in the United States. Numerous studies have examined the “stay and defend” option during a wildfire in Australia, and evacuation alternatives have also been examined in the US. However, evacuation alternatives have not yet received scholarly attention in Canada. This study focused on the community of Mt. Lorne, Yukon, and explored residents’ perceptions of alternatives to evacuation due to wildfires, their evacuation intentions, and factors that influenced their intentions. Focus group participants planned to stay on their property despite a wildfire evacuation order because of the perceived safety of their property, and concerns about evacuating including leaving their property unprotected, losing harvested meat or other food stocks due to spoiling, and not knowing what to do with sled dog teams or livestock. However, some of these residents lacked the knowledge about how to stay on their property safely.
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Levot, G. W. "Effective remediation of diazinon from spent sheep dip wash by disposal on land." Australian Journal of Experimental Agriculture 47, no. 1 (2007): 13. http://dx.doi.org/10.1071/ea05361.
Full textAbstract:
Spent sheep dip wash (about 3500 L) containing 59 mg diazinon/L was evenly distributed onto a 450-m2 grassed, soil-bunded, sloping site near Cumnock in central New South Wales, Australia. The entire volume was contained within the bunded area but surface run-off created ponding in the lowest corner of the site. The mean concentration within the top 7 cm of soil was 2.32 mg/kg a day after application. By day 14, this had dropped to 0.4 mg/kg and by day 56, was below the limit of quantification (0.1 mg/kg). The half-life of diazinon in soil was estimated to be 7 days. Residues in the next 7 cm of soil depth were much lower and were below the limit of quantification in all samples collected at day 28 or later. This suggests that vertical leaching of diazinon within the soil profile did not occur despite more than 95 mm of rain during the trial interval. Throughout the 56-day trial interval, diazinon concentrations in the top 7 cm of soil 3 m downhill of the lowest corner of the dip disposal site were unchanged from background pre-treatment levels. No diazinon was detected in samples at 7–14 cm depth in the soil profile in this area. With neither vertical nor lateral movement of diazinon away from the initial treatment zone, we consider the disposal of spent diazinon sheep dips as described here, to be an acceptable and convenient option for Australian wool producers and dipping contractors. Suitable dip disposal sites should be situated away from sensitive locations in areas that have good grass cover over deep soil and that are contained by an effective bund. Stock and other animals should be excluded from these sensitive locations.