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Academic literature on the topic 'Stereoselective reaction'

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Published: 6 September 2023

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Journal articles on the topic "Stereoselective reaction"

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Misra, Anup Kumar, Arin Gucchait, and Monalisa Kundu. "Synthesis of Pentasaccharide Repeating Unit Corresponding to the Cell Wall O-Polysaccharide of Salmonella enterica O55 Strain Containing a Rare Sugar 3-Acetamido-3-deoxy-d-fucose." Synthesis 53, no. 19 (June 24, 2021): 3613–20. http://dx.doi.org/10.1055/s-0037-1610777.

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AbstractA pentasaccharide repeating unit corresponding to the cell wall O-antigen of Salmonella enterica O55 containing a rare sugar, 3-acetamido-3-deoxy-d-fucose has been synthesized as its p-methoxyphenyl glycoside using a sequential stereoselective glycosylation strategy. A suitably functionalized 3-azido-3-deoxy-d-fucose thioglycoside derivative was prepared in very good yield and used in the stereoselective glycosylation reaction. Functionalized monosaccharide intermediates were prepared judiciously and stereoselectively assembled to get the desired pentasaccharide derivative in excellent yield.
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Rossi, Sergio, Tiziana Benincori, Laura Maria Raimondi, and Maurizio Benaglia. "3,3′-Bithiophene-Based Chiral Bisphosphine Oxides as Organocatalysts in Silicon-Derived Lewis Acid Mediated Reactions." Synlett 31, no. 06 (January 7, 2020): 535–46. http://dx.doi.org/10.1055/s-0039-1690777.

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This account summarizes the development of new biheteroaromatic chiral bisphosphine oxides. 3,3′-Bithiophene-based phosphine oxides (BITIOPOs) have been successfully used as organocatalysts to promote Lewis base catalyzed, Lewis acid mediated stereoselective transformations. These highly electron-rich compounds, in combination with trichorosilyl derivatives (allyltrichlorosilane and silicon tetrachloride), generate hypervalent silicon species that act as chiral Lewis acids in highly diastereo- and enantioselective organic reactions. Several relevant examples related to these applications are discussed in detail.1 Introduction2 The BITIOPO Family3 Enantioselective Opening of Epoxides4 Enantioselective Allylation of Aldehydes5 Stereoselective Direct (Double) Aldol-Type Reaction with Ketones6 Stereoselective Direct Aldol-Type Reaction with Ester Derivatives7 Conclusions
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Klegraf, Ellen, and Horst Kunz. "Stereoselective Synthesis of 3-Substituted and 3,4-Disubstituted Piperidine und Piperidin-2-one Derivatives." Zeitschrift für Naturforschung B 67, no. 4 (April 1, 2012): 389–405. http://dx.doi.org/10.1515/znb-2012-0413.

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The stereoselective synthesis of 3-substituted and 3,4-disubstituted piperidine and piperidin-2-one derivatives was achieved starting from 2-pyridone. After N-galactosylation and subsequent O-silylation, nucleophilic addition of organometallic reagents proceeded with high regio- and stereoselectivity at 4-position. Substituents at position 3 were stereoselectively introduced by reaction of electrophiles with amide enolates of the N-galactosyl-2-piperidones.
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Woo, Simon, Masood Parvez, and Brian A. Keay. "Regio- and stereoselective ring openings of unsymmetrical oxatricyclo adducts." Canadian Journal of Chemistry 75, no. 6 (June 1, 1997): 665–80. http://dx.doi.org/10.1139/v97-081.

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SN2′ ring-opening reactions of a number of substituted 11-oxatricyclo[6.2.1.01,6]undec-9-en-5-ones prepared via the intramolecular Diels–Alder reaction employing a furan diene (IMDAF) are reported. Primary, secondary, and tertiary organolithium reagents were capable of effecting the ring-opening reaction, while methyllithium required activation before any ring opening was observed. Hydride reagents, organocuprates, and Grignard reagents were generally ineffective. The ring-opening reaction was highly regio- and stereoselective for attack at C9syn to the bridging oxygen atom provided that C8 was not substituted. A highly stereoselective nucleophilic addition to the carbonyl group anti to the bridging oxygen was also observed. The high selectivity appears to be due to a combination of steric and electronic effects. Keywords: SN2′ reactions, oxatricyclo adducts, Diels–Alder reaction, ring opening.
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Penumati, Nageshwar Rao, and Nagaiah Kommu. "Stereoselective Synthesis of (+)-α-Conhydrine from R-(+)-Glyceraldehyde." Organic Chemistry International 2014 (October 20, 2014): 1–7. http://dx.doi.org/10.1155/2014/982716.

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Stereoselective synthesis of (+)-α-Conhydrine was accomplished from protected (R)-(+)-glyceraldehyde, a familiar carbohydrate predecessor. Our synthetic strategy featured the following two key reactions. One is Zn-mediated stereoselective aza-Barbier reaction of imine 6 with allyl bromide to afford chiral homoallylic amine 7, and the other is ring-closing metathesis.
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Schultz, Jeremy F., Bing Yang, and Nan Jiang. "Direct observation of the geometric isomer selectivity of a reaction controlled via adsorbed bromine." Nanoscale 12, no. 4 (2020): 2726–31. http://dx.doi.org/10.1039/c9nr09857g.

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Liu, Yuxiao, Yongming Deng, Peter Y. Zavalij, Renhua Liu, and Michael P. Doyle. "An efficient route to highly enantioenriched tetrahydroazulenes and β-tetralones by desymmetrization reactions of δ,δ-diaryldiazoaceto-acetates." Chemical Communications 51, no. 3 (2015): 565–68. http://dx.doi.org/10.1039/c4cc08255a.

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Ross, Günther, and Ivar Ugi. "Stereoselective syntheses of α-amino acid and peptide derivatives by the U-4CR of 5-desoxy-5-thio-D-xylopyranosylamine." Canadian Journal of Chemistry 79, no. 12 (December 1, 2001): 1934–39. http://dx.doi.org/10.1139/v01-186.

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Since 1961, the synthesis of α-amino acids derivatives by the four-component reaction of isocyanides (U-4CR) as a one-pot reaction has been developed. Only recently it was found that a variety of these α-amino acids compounds can be formed stereoselectively by the U-4CR using 1-amino-5-deoxy-5-thio-2,3,4-tri-O-isobutanoyl-β-D-xylopyranose as the amine component. The stereoselectivity inducing auxiliary 5-desoxy-5-thio-D-xylopyranosyl group of the so-formed products can be replaced selectively by hydrogen.Key words: stereoselective U-4CR, chiral amine component, amino carbohydrate, α-amino acid derivatives.
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Cantin, Michel, Yao-Chang Xu, and Pierre Deslongchamps. "Stereocontrolled construction of A.B.C.[6.6.6] tricycle via transannular Diels–Alder reaction of 14-membered triene macrocycle." Canadian Journal of Chemistry 68, no. 12 (December 1, 1990): 2144–52. http://dx.doi.org/10.1139/v90-329.

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The synthesis of the four acyclic trienes 11a, b and 20a, b is reported. The tandem macrocyclization and stereoselective transannular Diels–Alder reaction of acyclic trienes 11b (trans-trans-cis) and 20b (trans-trans-trans) were observed in the presence of Cs2CO3 at 85 °C to give tricycles 30 (TST) and 32 (CAT) respectively. However, treatment of acyclic trienes 11a (cis-trans-cis) and 20a (cis-trans-trans) under the same conditions yielded the 14-membered macrocycles 21 and 23, which were stereoselectively transformed at 250 °C into tricycles 22 (CST) and 24 (CAT) respectively in excellent yield. Keywords: stereocontrolled synthesis, macrocycle, tricyclic compound, transannular Diels–Alder reaction.
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Sugita, Kazuyuki, Motoi Kuwabara, Ami Matsuo, Shogo Kamo, and Akinobu Matsuzawa. "Stereoselective Convergent Synthesis of Carbon Skeleton of Cotylenin A Aglycone." Synthesis 53, no. 12 (February 1, 2021): 2092–102. http://dx.doi.org/10.1055/s-0040-1706684.

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AbstractIn this paper, the synthesis of the carbon skeleton of cotylenin A aglycone is described. The key reactions, including an intramolecular aldol reaction, an aldol coupling reaction, and a ring-closing meta­thesis, allow for the effective and stereoselective access to the carbon skeleton of cotylenin A aglycone. The stereochemistry was confirmed by single-crystal X-ray crystallographic analyses of related compounds.
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Dissertations / Theses on the topic "Stereoselective reaction"

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Millet, Julien. "Approaches towards a stereoselective Nicholas reaction." Thesis, Kingston University, 2006. http://eprints.kingston.ac.uk/20379/.

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This programme of work has focused on developing ways of inducing stereoselectivity into the Nicholas reaction towards the synthesis of natural products. The first chapter of the thesis reviews the developments ofthe Nicholas reaction since its discovery in 1972 as well as other applications of cobalt clusters. The following chapter describes chirality and various approaches towards asymmetric synthesis. Chapter 3 details our investigations as well as the results that we achieved in the two ' areas we explored. The first part of the project attempted to determine which oxazolidinone derivative would provide optimum levels of selectivity in 1, 4-conjugate addition reactions, and then investigate such derivatives in the Nicholas reaction. It was found that oxazolidinones bearing a phenyl group at the C4 position induced much higher levels • ,rof stereoselectivity than those with benzyl or methyl groups at the C4 position. Although 4-phenyl-2-oxazolidinone provided optimum levels of diastereoselectivity in the asymmetric conjugate addition reaction of pentenyl organometallic reagents, it proved less efficient when applied sequencially in an intermolecular Nicholas reaction. In contrast, 4-methyl-2-oxazolidinone provided poor selectivity in an asymmetric conjugate addition reaction; however it was the auxiliary of choice for the corresponding Nicholas reaction providing optimum levels ofdiastereoselectivity. In the second part of our project, we focused on studying the intramolecular Nicholas reaction carried out upon optically active propargyl alcohols derived from citronella!. These were prepared from two different approaches. In the first approach, racemic propargyl alcohols were prepared via a Grignard reaction, then oxidised to the corresponding ketone before being reduced to the optically pure alcohol via a stereoselective reduction using alpine borane®. In the second approach, optically active propargyl alcohols were prepared via zinc catalysed asymmetric alkynylation reactions. After complexation of these propargyl alcohols to cobalt octacarbonyl, the addition of a Lewis acid led to the intramolecular Nicholas cyclisation reaction providing tri-substituted six membered rings in 55% yield. The results show that the reactions carried out on opposite diastereoisomers or racemic mixture provided the same mixture of diastereoisomers of the cyclised products. The final chapter describ~s all the experimental procedures that were carried out as well as the characterisation of every compound presented in this document.
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Rutherford, Alistair Peter. "Stereoselective synthesis of #Beta#-hydroxycyclohexanones using the anionic oxy-cope rearrangement." Thesis, University of Glasgow, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.299981.

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LOPS, CARMINE. "Development of organocatalytic and stereoselective reactions." Doctoral thesis, Università degli Studi di Trieste, 2018. http://hdl.handle.net/11368/2918472.

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Il focus di questo dottorato è stato lo sviluppo di due reazioni organocatalitiche e stereoselettive: le addizioni di sulfa-Michael e le condensazioni di Darzens poiché rappresentano degli approcci sintetici interessanti per la sintesi di farmaci chirali e, nell’ambito farmaceutico, ci sono pochi principi attivi (API) sintetizzati con reazioni di SMAs e/o di Darzens organocatalitiche e stereoselettive. Nell’ambito delle addizioni di sulfa-Michael (SMAs), la catalisi mediata da molecole bifunzionali donatrici di legami ad idrogeno (HBD) rappresenta un approccio interessante per l'attivazione sia della componente nucleofila che di quella elettrofila di una reazione. Gli esempi di SMA stereoselettive catalizzate da HBD bifunzionali e aventi il trans-chalcone come accettore di Michael sono pochi. Con l’obiettivo di ottimizzare l’attivitá dei catalizzatori HBD, la letteratura suggerisce come l'aumento dell'acidità dei protoni tioureici NH abbia effetti positivi sulle velocità di alcune reazioni. Spinto da queste informazioni, si è deciso di eseguire un'analisi comparativa di alcuni catalizzatori HBD in SMA stereoselettive aventi il trans-calcone come accettore di Michael. All’inizio, abbiamo studiato l'effetto della quantitá di catalizzatore, del solvente e della temperatura nella reazione modello: l'addizione del fenilmetantiolo al trans-calcone. Successivamente, con le condizioni di reazione ottimizzate, abbiamo valutato la capacità di indurre stereoselezione da parte di alcuni catalizzatori HBDs nelle SMAs stereoselettive del benzentiolo, fenilmetantiolo e 2-feniletantiolo al trans-calcone. L'aumento dell'acidità di Brønsted nella porzione donatrice di legami ad idrogeno ha dato, in alcuni casi, reazioni più rapide ma, in generale, ha avuto un impatto negativo sulla stereoselettività. Inoltre, il prodotto ottenuto dall’addizione del benzentiolo al trans-calcone è risultato stereochimicamente instabile, poiché subisce una reazione di retro-Michael quando lasciato in presenza di catalizzatori, come nel caso di un ritardato work-up della reazione. Per quanto riguarda le condensazioni di Darzens, generalmente, sono condotte in presenza di basi forti come idrossidi o alcossidi di metalli alcalini, sodio ammide, LDA, LiHMDS o n-butil-litio. In letteratura, non ci sono esempi di reazioni di Darzens condotte in presenza di basi organiche neutre. Quindi, si è deciso di studiare la reazione di Darzens in presenza di basi organiche neutre aventi una diversa pKBH+. La reazione, in presenza di una quantità stechiometrica di fosfazene P1-t-Bu, genera gli epossidi cis e trans con una buona resa e con un breve tempo di reazione. Tuttavia, sia i problemi di stabilità che le difficoltà di preparazione delle basi fosfazeniche, rendono importante l’obiettivo di identificare nuove superbasi. A tal fine, è stata valutata la ciclopropenimmina, con una pKBH+ simile a quella di P1-t-Bu. Con l’impiego di una quantità stechiometrica di ciclopropenimmina, l'epossido è stato ottenuto con una resa fino al 34% e 1/0.85 d.r. cis/trans. Usando una quantità catalitica di ciclopropenimmina (30 mol%), i composti α,β-epossicarbonilici sono stati ottenuti con una resa fino all'86% e 1/0.6 d.r. cis/trans; dimostrando di essere tollerante sia alle variazioni strutturali che alle proprietà elettroniche delle aldeidi aromatiche e dei composti carbonilici impiegati.
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Thomas, Jermaine D. O. "Highly regio and stereoselective hydroxy-directed Diels-Alder reaction." Thesis, University of Ottawa (Canada), 2002. http://hdl.handle.net/10393/6123.

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The Diels-Alder reaction has proven to be an invaluable tool in the arsenal of the synthetic organic chemist for the relatively facile construction of cyclic cores. However, the utility of this reaction is not without its shortcomings. Lack of regio and stereoselectivity are two problems that are often encountered with asymmetric dienophiles. Although Lewis acids have been successfully employed to control the selectivity of Diels-Alder reactions involving activated dienophiles, there is little precedent in the literature for their use with dienes containing a tertiary alcohol functionality, due to elimination complications. To this end, a new method has been developed, and reported herein, for the control of both the regio and facial selectivity of the Diels-Alder reaction via a Lewis acid tether to the dienophile directed by the tertiary alcohol on the diene.* *Please refer to dissertation for diagrams.
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Dawson, Graham John. "Studies on the stereoselective palladium-catalysed allylic substitution reaction." Thesis, Loughborough University, 1995. https://dspace.lboro.ac.uk/2134/31866.

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This thesis contains the preparation of a new design of ligand for the palladium catalysed allylic substitution reaction. The phosphine oxazoline ligands detailed in the thesis give high levels of enantiocontrol when used in conjunction with symmetrical allyl systems in the palladium catalysed allylic substitution reaction. For unsymmetrical allyl systems the palladium catalysed allylic substitution process proceeds with complete regiocontrol and high levels of stereocontrol are again observed. The products from the palladium catalysed allylic substitution reaction can be readily converted to succinic acids, γ-lactones and aryl propanoic acids.
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Beligny, Samuel Daniel Charles. "Stereoselective synthesis of tetrahydropyridines using the Diels-Alder reaction." Thesis, Imperial College London, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.414751.

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Takano, Toshiyuki. "SYNTHESIS OF CELLO-OLIGOSACCHARIDES -INFLUENCE OF SUBSTITUENT GROUPS ON STEREOSELECTIVE GLYCOSYLATION REACTION-." Kyoto University, 1990. http://hdl.handle.net/2433/78226.

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Cresswell, Mark. "The stereoselective Pictet-Spengler reaction and studies towards the total synthesis of ajmaline." Thesis, Keele University, 2013. http://eprints.keele.ac.uk/3816/.

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Due to their extensive and important medicinal properties, the indole alkaloids are an important class of natural products. A key step towards the total synthesis of indole alkaloids is the diastereoselective Pictet-Spengler reaction, which has enabled the total syntheses of a number of these natural products to be reported, one of which is the medicinally-important alkaloid ajmaline. Ajmaline is well studied and the previous attempts towards its synthetic preparation are described. During our investigations towards the asymmetric syntheses of ajmaline and other related indole alkaloids, it was found that the kinetically-controlled Pictet-Spengler cyclisations of L-tryptophan allyl ester gave cis-3,5-disubstituted tetrahydro-β- carbolines with enhanced stereoselectivities of up to 20:1. The Pictet-Spengler reaction of L-tryptophanamide was also studied and the cis/trans tetrahydro-β- carbolines were formed in a ratio of 3:1, typical of that for other ineticallycontrolled Pictet-Spengler cyclisations reported previously. Studies towards our total synthesis of ajmaline are also described. The synthesis features the kinetically-controlled Pictet-Spengler reaction, a highly stereoselective intramolecular Michael cyclisation and a one-pot indole cyclisation/reduction procedure, which was used to introduce three stereocentres simultaneously. It was found that the nitrogen protecting group has a defining role to play in both the indole cyclisation step, and during reduction of the subsequent iminium ion through remote steric induction. Despite installing seven of the nine stereocentres with high levels of stereocontrol, an inability to remove the robust nitrogen amide protecting group prevented completion of a total synthesis. The final ring-closing protocol could be carried out using semi-synthetic material derived from ajmaline. Cyclisation was achieved by the selective oxidation of a primary alcohol to the aldehyde, which spontaneously ring closed under the conditions of the reaction to complete the ajmaline framework.
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Herlé, Bart. "Stereoselective Cyclopropanations via Gold(I)-Catalyzed Retro-Buchner Reactions." Doctoral thesis, Universitat Rovira i Virgili, 2017. http://hdl.handle.net/10803/454770.

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La formació de carbens bencílics d’or(I) a partir de cicloheptatriens substituïts en la posició 7, a través de la reacció de retro-Buchner, ha aparegut recentment com una alternativa segura i versàtil a la descomposició de diazocompostos. No obstant, la formació de dits carbens requereix altes temperatures, limitant la seva aplicació. El treball d’aquest tesi doctoral s’ha dedicat a superar aquesta desavantatge i millorar la versatilitat de la transformació. Els derivats de 1H-ciclopropa[l]fenantrè, que s’assemblen al tautòmer norcaradiè del cicloheptatriè, es descomponen per donar lloc a carbens lliures mitjançant la irradiació amb llum. Es va investigar la formació de carbens d’or(I) amb derivats de fenantrè mitjançant la reacció de retro-Buchner. No obstant, no es va trobar cap millora significativa amb respecte l’ús de derivats de cicloheptatriè. Per altre banda, la generació de carbens al·lílics d’or(I) a partir de 7-alquenilcicloheptatriens, té lloc a temperatures significativament més baixes. Tenint en compte aquest fet, es va desenvolupar una reacció de ciclopropanació d’olefines per donar vinil-ciclopropans i vinil-aminociclopropans amb bons rendiments i elevada selectivitat per donar l’isòmer cis. Els derivats de 7-alquenil-cicloheptatriè es formen en un sol pas a partir d’aldehids i cetones emprant un nou reactiu del tipus Julia-Kocienski. Addicionalment, utilitzant tècniques experimentals i computacionals, es van estudiar els mecanismes mediats per or(I) de la reacció de retro-Buchner, de la ciclopropanació i de la reacció de epimerització dels vinil-ciclopropans. Això va permetre el desenvolupament d’un model esteroquímic avançat per a les reaccions de ciclopropanació catalitzades per or(I). El coneixement aportat per els estudis mecanístics i la síntesi millorada de derivats de cicloheptatriè van permetre la síntesi de derivats de cicloheptatriè més congestionats estèricament, què donen lloc a carbens d’or(I) a temperatura ambient i són el punt de partida per al desenvolupament d’una ciclopropanació enantioselectiva de gran aplicació.
La formación de carbenos bencílicos de oro(I) a partir de cicloheptatrienos sustituídos en la posición 7, a través de la reacción de retro-Buchner, ha surgido recientemente como una alternativa segura y versátil a la descomposición de diazocompuestos. Sin embargo, la formación de dichos carbenos tiene lugar a altas temperaturas, limitando su aplicación. El trabajo de esta tesis doctoral se dedicó a superar esta desventaja y a mejorar la versatilidad de la transformación. Los derivados de 1H-ciclopropa[l]fenantreno, que se asemejan al tautómero norcaradieno del cicloheptatrieno, se descomponen para dar lugar a carbenos libres mediante irradiación con luz. Se investigó la formación de carbenos de oro(I) con derivados de fenantreno, a través de la reacción de retro-Buchner. No obstante, no se encontró ninguna mejora significativa con respecto al uso de derivados de cicloheptatrieno. Por otro lado, la generación de carbenos alílicos de oro(I) a partir de 7-alquenil-cicloheptatrienos, tiene lugar a temperaturas significativamente más bajas. Dada esta observación, se desarrolló una reacción de ciclopropanación de olefinas para dar vinil-ciclopropanos y vinil-aminociclopropanos en buenos rendimientos y con elevada selectividad para el isómero cis. Los derivados de 7-alquenil-cicloheptatrieno son formados en un sólo paso a partir de aldehídos y cetonas utilizando un nuevo reactivo de tipo Julia-Kocienski. Adicionalmente, utilizando técnicas experimentales y computacionales, se estudiaron los mecanismos mediados por oro(I) de la reacción de retro-Buchner, de la ciclopropanación y de la reacción de epimerización de los vinilciclopropanos. Esto permitió el desarrollo de un modelo estereoquímico avanzado para las reacciones de ciclopropanación catalizadas por oro(I). El conocimiento aportado por los estudios mecanísticos y la síntesis mejorada de derivados de cicloheptatrieno, permitieron la síntesis de derivados de cicloheptatrieno más estéricamente congestionados, que dan lugar a carbenos de oro(I) a temperatura ambiente y son el punto de partida para el desarrollo de una ciclopropanción enantioselectiva de gran aplicación.
The formation of benzylic gold(I) carbenes from 7-substituted cycloheptatrienes via a retro-Buchner reaction has recently emerged as a safe and versatile alternative to decomposition of diazo compounds. However, the carbene formation takes places at high temperatures, which puts a limit on its application. The work in this thesis is dedicated to overcome this drawback and enhance the versatility of this transformation. Free carbenes can be generated from light-induced decomposition of 1H-cyclopropa[l]phenanthrenes, which bear great resemblance to the norcaradiene tautomer of cycloheptatriene. Therefore, the propensity to form gold(I) carbenes via the retro-Buchner reaction of phenanthrene derivatives was investigated, albeit without finding significant improvements over the cycloheptatriene derivatives. The formation of allylic gold(I) carbenes from 7-alkenyl cycloheptatrienes takes place at significantly lower temperatures. Based on this observation, a highly cis-selective olefin cyclopropanation reaction has been developed, affording vinylcyclopropanes and vinyl-aminocyclopropanes in moderate to good yield. The 7-alkenyl cycloheptatriene derivatives can be formed in a single step from aldehydes and ketones by a novel Julia-Kocienski reagent. The mechanisms of the gold(I)-mediated retro-Buchner, cyclopropanation, and epimerization reactions for vinylcyclopropanes have been studied experimentally and computationally, which led to the development of an advanced stereomodel for gold(I)-catalyzed cyclopropanation reactions. Owing to the mechanistic insights, and the improved strategy for the synthesis of cycloheptatriene reagents, a sterically encumbered cycloheptatriene derivative was developed, which allows the formation of gold(I) carbenes at room temperature, paving the way for a broad-scope enantioselective cyclopropanation reaction.
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Peace, Simon. "The stereoselective nitro-Mannich reaction and its application towards the synthesis of vicinal diamines." Thesis, University of Sheffield, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287661.

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Books on the topic "Stereoselective reaction"

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Mahrwald, Rainer, ed. Modern Methods in Stereoselective Aldol Reactions. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527656714.

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Ozawa, Yu. Copper(I)-Catalyzed Stereoselective Borylation Reactions. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-1098-4.

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Science of synthesis: Stereoselective synthesis : Stereoselective reactions of carbonal and imino groups. Stuttgart: Georg Thieme, 2011.

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Science of synthesis: Stereoselective synthesis : Stereoselective reactions of carbon--carbon double bonds. Stuttgart: Georg Thieme, 2011.

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Modern biocatalysis: Stereoselective and environmentally friendly reactions. Weinheim: Wiley-VCH, 2009.

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Rodriguez, Jean, and Damien Bonne. Stereoselective multiple bond-forming transformations in organic synthesis. Hoboken, New Jersey: John Wiley & Sons, Inc., 2015.

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Wiktelius, Daniel. Asymmetric synthesis of dipeptidomimetics and phosphine-boranes: Routes involving stereoselective olefination, expoxidation, and lipase-catalysed reactions. Göteborg: Göteborg University, 2007.

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Dr, Werner Helmut Prof, and Sundermeyer Jörg, eds. Stereoselective reactions of metal-activated molecules: Proceedings of the second symposium held in Würzburg, September 21-23, 1994. Braunschweig: Vieweg, 1995.

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Dawson, Graham John. Studies on the stereoselective palladium catalysed allylic substitution reaction. 1995.

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de Vries, J. G., K. Muñiz, G. Franciò, W. Leitner, P. L. Alsters, K. D. Schleicher, T. F. Jamison, et al. Stereoselective Synthesis 1 Stereoselective Reactions of Carbon—Carbon Double Bonds. Georg Thieme Verlag KG, 2011. http://dx.doi.org/10.1055/sos-sd-201-00000.

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Book chapters on the topic "Stereoselective reaction"

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Gryko, Dorota, and Dominika Walaszek. "C-C Bond Formation by Aldol Reaction." In Stereoselective Organocatalysis, 81–127. Hoboken, New Jersey: John Wiley & Sons, Inc., 2013. http://dx.doi.org/10.1002/9781118604755.ch03.

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Zhang, Yong, and Wei Wang. "CC Bond Formation by Michael Reaction." In Stereoselective Organocatalysis, 147–203. Hoboken, New Jersey: John Wiley & Sons, Inc., 2013. http://dx.doi.org/10.1002/9781118604755.ch05.

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Khiar, Noureddine, Inmaculada Fernández, Ana Alcudia, Maria Victoria García, and Rocío Recio. "Reaction of Enolates." In Carbohydrates - Tools for Stereoselective Synthesis, 47–63. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527654543.ch3.

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Quinkert, G., and M. Grosso. "Progress in the Diels/Alder Reaction Means Progress in Steroid Synthesis." In Stereoselective Synthesis, 109–34. Berlin, Heidelberg: Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-78496-5_6.

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Gallego, Mar Gómez, and Miguel A. Sierra. "Level 2 — Case 29 Stereoselective Debromination of Vicinal Dibromides." In Organic Reaction Mechanisms, 189–96. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-642-18788-9_29.

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Gallego, Mar Gómez, and Miguel A. Sierra. "Level 2 — Case 31 Stereoselective Synthesis of 2-Acylaziridines." In Organic Reaction Mechanisms, 203–9. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-642-18788-9_31.

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Cordes, Martin, and Markus Kalesse. "The Vinylogous Mukaiyama Aldol Reaction in Natural Product Synthesis." In Modern Methods in Stereoselective Aldol Reactions, 83–154. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527656714.ch2.

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Sun, Ho-Yan, and Dennis G. Hall. "At the Forefront of the Suzuki–Miyaura Reaction: Advances in Stereoselective Cross-Couplings." In Synthesis and Application of Organoboron Compounds, 221–42. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-13054-5_7.

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Li, Jie Jack. "Keck stereoselective allylation." In Name Reactions, 213–14. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-662-05336-2_157.

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Li, Jie Jack. "Keck stereoselective allylation." In Name Reactions, 188–89. Berlin, Heidelberg: Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-662-04835-1_147.

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Conference papers on the topic "Stereoselective reaction"

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Gonçalves, Vanessa P., Rodrigo M. S. Justo, and Giovanni W. Amarante. "Chiral Brønsted Acid Catalyzed Highly Stereoselective Mannich-type reaction of Azlactone with Aldimines." In 15th Brazilian Meeting on Organic Synthesis. São Paulo: Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_20139216537.

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Netscher, Thomas, and Ann-Christine Loesche. "On the Mechanism of the Acid-Catalyzed Stereoselective Chroman Cyclization Reaction." In The 20th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2016. http://dx.doi.org/10.3390/ecsoc-20-b005.

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Marini, Francesca, Valentina Frullini, Silvia Sternativo, Luana Bagnoli, and Claudio Santi. "Stereoselective synthesis of cyclopropanes from vinyl selenones via a Michael-initiated ring closure reaction." In The 17th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2013. http://dx.doi.org/10.3390/ecsoc-17-a011.

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Fernandes, Alessandra A. de G., Bruna L. Papa, and Alessandro Rodrigues. "Virtual Screening of New Potential Organocatalysts for Stereoselective Nitroaldol Reactions." In 15th Brazilian Meeting on Organic Synthesis. São Paulo: Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_201391516283.

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Fulas, Marcia, Jéssica de S. Figueiredo, and Alessandro Rodrigues. "Organocatalysts: Design, Synthesis and Application in Stereoselective Domino-Michael/Henry Reactions." In 15th Brazilian Meeting on Organic Synthesis. São Paulo: Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_2013915201517.

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Oliveira, Caio C., Emerson Andrade Ferreira dos Santos, and Carlos Roque Duarte Correia. "Substrate Directable Heck-Matsuda Reactions: A Short and Stereoselective Total Synthesis of S1P1 Agonist." In 14th Brazilian Meeting on Organic Synthesis. São Paulo: Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0163-1.

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Bhushan, Indu. "Efficient media for high production of microbial lipase from Bacillus subtilis (BSK-L) using response surface methodology for enantiopure synthesis of drug molecules." In 2nd International Scientific Conference "Plants and Microbes: the Future of Biotechnology". PLAMIC2020 Organizing committee, 2020. http://dx.doi.org/10.28983/plamic2020.044.

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Abstract:
Lipases are a multipurpose enzyme that holds a significant position in industrial applications due to its ability to catalyse a large number of reactions such as hydrolysis, esterification, interesterification, transesterification which makes it a potential candidate. It is also used for the separation of chiral drugs from the racemic mixture and this property of lipase is considered very important in pharmaceutical industries for the synthesis of enantiopure bioactive molecules. Assuming the tremendous importance of lipases, as stereoselective biocatalysts, in pharmaceuticals and various other commercial applications, industrial enzymologists have been forced to search for those microorganisms which are able to produce novel biocatalysts at reasonably high yield. In the present study microbial lipase was isolated from the water sample of pond at Katra, Jammu and Kashmir (India). This enzyme has shown wide specificity and higher enantioselectivity, which make it pharmaceutical important enzyme. To make it economical for industrial application, it was produced on cheap nutrient media using Response Surface Methodology and got maximum production. It was used for resolution of chiral drugs and the significant results obtained during the course of work shall have potential towards pharmaceutical industries.
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Reports on the topic "Stereoselective reaction"

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Brown, Herbert C., and Ashok M. Salunkhe. Stereoselective Synthesis of cis-and trans-Beta,Gamma-Unsaturated Carboxylic Esters via Reaction of Alkenyldichloroboranes with Ethyl Diazoacetate. Fort Belvoir, VA: Defense Technical Information Center, July 1991. http://dx.doi.org/10.21236/ada239049.

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