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Books on the topic 'Stem cells – Research – Animal models'

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Published: 4 June 2021
Last updated: 5 February 2022

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1

Animal models for stem cell therapy. [New York]: Humana Press, 2014.

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2

Media, Springer Science+Business, ed. Stem cells and tissue repair: Methods and protocols. New York: Humana Press, 2014.

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3

Brakebusch, Cord. Mouse as a Model Organism: From Animals to Cells. Dordrecht: Springer Science+Business Media B.V., 2011.

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4

S, Koka Prasad, ed. Leading-edge stem cell research. New York: Nova Science Publishers, 2008.

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5

Kursad, Turksen, ed. Embryonic stem cell protocols. 2nd ed. Totowa, N.J: Humana Press, 2006.

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6

Turksen, Kursad. Embryonic Stem Cell Protocols: Volume II: Differentiation Models (Methods in Molecular Biology). 2nd ed. Humana Press, 2006.

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7

Embryonic stem cell protocols: Volume 1: isolation and characterization. 2nd ed. Totowa, NJ: Humana Press, 2006.

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8

Turksen, Kursad. Embryonic Stem Cell Protocols: Volume I: Isolation and Characterization (Methods in Molecular Biology). 2nd ed. Humana Press, 2006.

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9

Drapeau, Elodie, Hala Harony-Nicolas, and Jacqueline N. Crawley. Animal and Cellular Models of Pediatric Psychiatric Disorders. Edited by Dennis S. Charney, Eric J. Nestler, Pamela Sklar, and Joseph D. Buxbaum. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190681425.003.0061.

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The study of childhood psychiatric disorders is especially challenging, not only because of the difficulties in obtaining relevant human samples but also because of ethical considerations regarding the ability of children to provide informed consent. Models that can be experimentally manipulated are therefore indispensable to study those disorders. Traditionally, biological psychiatry research has extensively employed animal models and characterizations of rodent behavior. More recently, induced pluripotent stem cells (iPSCs), and induced differentiation of iPSCs into different types of brain cells have offered new alternative strategies to elucidate mechanisms underlying cellular processes. Regardless of how they are created, optimal models should demonstrate face validity, construct validity, and predictive validity to be considered most relevant. This chapter highlights the major animal and cellular models currently used in the research of childhood-onset psychiatric disorders.
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10

Schatt, Stephan. An animal model for in utero HSC transplantation and the role of cytokine secretion by T- and NK cells in pregnancy /von Stephan Schatt. Schatt, 2000.

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11

H, Baron Margaret, ed. Developmental hematopoiesis: Methods and protocols. Totowa, N.J: Humana Press, 2005.

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12

Hematopoietic Stem Cells Animal Models And Human Transplantation. Springer, 2012.

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13

C, Müller-Sieburg, ed. Hematopoietic stem cells: Animal models and human transplantation. Berlin: Springer-Verlag, 1992.

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14

Elena, Notarianni, and Evans Martin J. Prof, eds. Embryonic stem cells: A practical approach. Oxford: Oxford University Press, 2006.

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15

V, Greer Erik, ed. Neural stem cell research. New York: Nova Science Publishers, 2006.

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16

MULLER-SIEBURG, CHRISTA ED. Hematopoietic Stem Cells: ANIMAL MODELS AND HUMAN TRANSPLANTATION (Current Topics in Microbiology & Immunology). Springer, 1992.

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17

(Editor), Elena Notarianni, and Martin J. Evans (Editor), eds. Embryonic Stem Cells: A Practical Approach (Practical Approach Series). Oxford University Press, USA, 2006.

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18

(Editor), Elena Notarianni, and Martin J. Evans (Editor), eds. Embryonic Stem Cells: A Practical Approach (The Practical Approach Series). Oxford University Press, USA, 2006.

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19

1952-, Teicher Beverly A., ed. Tumor models in cancer research. Totowa, N.J: Humana Press, 2002.

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20

Yannas, Ioannis V. Regenerative Medicine I: Theories, Models and Methods. Springer, 2010.

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21

Developmental Hematopoiesis (Methods in Molecular Medicine,). Humana Press, 2005.

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22

H, Baron Margaret, ed. Developmental hematopoiesis: Methods and protocols. Totowa, N.J: Humana Press, 2005.

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23

Regenerative Medicine I: Theories, Models and Methods (Advances in Biochemical Engineering / Biotechnology). Springer, 2005.

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24

Bins, Adriaan D. Induction and Analysis of Antigen-specific T cell Responses in Melanoma Patients and Animal Models. Amsterdam University Press, 2007.

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25

Fibrosis research: Methods and protocols. Totowa, N.J: Humana Press, 2005.

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26

Pletnikov, Mikhail V., Guo-Li Ming, and Christopher A. Ross. Animal and Cellular Models of Psychotic Disorders. Edited by Dennis S. Charney, Eric J. Nestler, Pamela Sklar, and Joseph D. Buxbaum. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190681425.003.0015.

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Animal and cell models are experimental systems developed to study particular aspects of a disease, as no model can accurately reflect all features of the disease. In this critical review we mention some of the nongenetic models but focus on genetic mouse models, evaluate their advantages and limitations, and comment on potential new prospects for the field. The ability to reprogram somatic cells from patients and unaffected donors to induced pluripotent stem cells (iPSCs) has the potential to substantially enhance our knowledge of normal cellular development and disease pathogenesis. The use of cell and animal models will help elucidate basic cellular and molecular mechanisms of pathogenesis, which will enable the development of targeted therapeutic approaches.
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27

(Editor), John Varga, David A. Brenner (Editor), and Sem H. Phan (Editor), eds. Fibrosis Research: Methods and Protocols (Methods in Molecular Medicine). Humana Press, 2005.

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28

Pihlajaniemi, Taina, and Cord Brakebusch. Mouse as a Model Organism: From Animals to Cells. Springer, 2014.

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29

Brennand, Kristen. Application of Stem Cells to Understanding Psychiatric Disorders. Edited by Dennis S. Charney, Eric J. Nestler, Pamela Sklar, and Joseph D. Buxbaum. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190681425.003.0005.

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While much has been learned through clinical post-mortem and neuroimaging studies of patients and animal models of autism spectrum disorder (ASD), bipolar disorder (BD) and schizophrenia (SZ), these classical approaches have yet to fully elucidate the interaction of complex genetic risk factors on disease predisposition. The derivation of human induced pluripotent stem cells (hiPSCs) from patients with psychiatric disorders permits the study of the full complement of risk variants (known and unknown) that underlie disease predisposition, precisely in the cell types relevant to disease. The following chapter covers work to date regarding the advancements in the use of hiPSCs to model psychiatric disorders.
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30

Dietz, Volker, and Nick S. Ward, eds. Oxford Textbook of Neurorehabilitation. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198824954.001.0001.

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In the new edition of the Oxford Textbook of Neurorehabilitation all chapters have been updated to reflect advances in knowledge in the field of neurorehabilitation. It will be supplemented by additional chapters that reflect novel developments in the field of neurorehabilitation. During recent years there has been a strong evolution in the field of vocational rehabilitation with the aim of helping people after an injury of the nervous system to overcome the barriers and return to employment. A new chapter on self-management strategies deals with building confidence in individuals to manage the medical and emotional aspects of their condition. Furthermore, today the scientific basis for music supported therapy is a much broader to introduce it in this edition. New guidelines and consensus statements became established concerning preclinical research, biomarkers, and outcome measures, in both animal models and human beings. There are new data on attempts (e.g. using stem cells or Nogo antibodies) to restore function after spinal cord injury and stroke. Not all of these therapies and clinical trials have had positive outcomes. One particular area of rapid expansion reflects the use of technology in neurorehabilitation and several chapters remain devoted to this topic in various forms. Still a better understanding of the interactions of technology led therapies and conventional approaches in patients with neurodisability is required. There is still work to be done in defining key components of all neurorehabilitation interventions in order to understand how they might best be delivered for maximum benefit.
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31

Juliana, González, Universidad Nacional Autónoma de México. Facultad de Filosofía y Letras., Mexico. Comisión Nacional de Derechos Humanos., and Fondo de Cultura Económica (Mexico), eds. Dilemas de bioética. México, D.F: UNAM-Facultad de Filosofía y Letras, 2007.

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32

Denman, Robert B. Modeling Fragile X Syndrome. Springer, 2011.

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33

Denman, Robert B. Modeling Fragile X Syndrome. Springer, 2013.

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34

Modeling Fragile X Syndrome. Springer, 2011.

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35

Charney, Dennis S., Eric J. Nestler, Pamela Sklar, and Joseph D. Buxbaum, eds. Charney & Nestler's Neurobiology of Mental Illness. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190681425.001.0001.

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In the years following publication of the DSM-5, the field of psychiatry has seen vigorous debate between the DSM’s more traditional, diagnosis-oriented approach and the NIMH’s more biological, dimension-based RDoC approach. Charney & Nestler’s Neurobiology of Mental Illness is an authoritative foundation for translating information from the laboratory to clinical treatment, and this edition extends beyond its reference function to acknowledge and examine the controversies and thoughts on the future of psychiatric diagnosis. In this wider context, this book provides information from numerous levels of analysis including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, epidemiology, and behavior. Section I, which reviews the methods used to examine the biological basis of mental illness in animal and cell models and in humans, has been expanded to reflect important technical advances in complex genetics, epigenetics, stem cell biology, optogenetics, neural circuit functioning, cognitive neuroscience, and brain imaging. These established and emerging methodologies offer groundbreaking advances in our ability to study the brain and breakthroughs in our therapeutic toolkit. Sections II through VII cover the neurobiology and genetics of major psychiatric disorders: psychoses, mood disorders, anxiety disorders, substance use disorders, dementias, and disorders of childhood onset. Also covered within these sections is a summary of current therapeutic approaches for these illnesses as well as the ways in which research advances are now guiding the search for new treatments. The last section, Section VIII, focuses on diagnostic schemes for mental illness. This includes an overview of the unique challenges that remain in diagnosing these disorders given our still limited knowledge of disease etiology and pathophysiology. The section then provides reviews of DSM-5 and RDoC. Also included are chapters on future efforts toward precision and computational psychiatry, which promise to someday align diagnosis with underlying biological abnormalities.
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36

M, Pubols Lillian, Sessle Barry J. 1941-, and International Union of Physiological Sciences. Congress, eds. Effects of injury on trigeminal and spinal somatosensory systems: Proceedings of a satellite symposium of the XXX Congress of the International Union of Physiological Sciences held at Timberline Lodge, Oregon, July 20-23, 1986. New York: Liss, 1987.

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