Relevant bibliographies by topics / Staphylococcus

Academic literature on the topic 'Staphylococcus'

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Published: 4 June 2021
Last updated: 30 July 2024

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Journal articles on the topic "Staphylococcus"

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Skalka, B. "Typing of Staphylococcus aureus, Staphylococcus intermedius and Coagulase-negative Staphylococci by Means of Staphylococcal Bacteriocins." Acta Veterinaria Brno 55, no. 4 (1986): 333–42. http://dx.doi.org/10.2754/avb198655040333.

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Fernández-Fernández, Rosa, Carmen Lozano, Rine Christopher Reuben, Laura Ruiz-Ripa, Myriam Zarazaga, and Carmen Torres. "Comprehensive Approaches for the Search and Characterization of Staphylococcins." Microorganisms 11, no. 5 (May 18, 2023): 1329. http://dx.doi.org/10.3390/microorganisms11051329.

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Novel and sustainable approaches are required to curb the increasing threat of antimicrobial resistance (AMR). Within the last decades, antimicrobial peptides, especially bacteriocins, have received increased attention and are being explored as suitable alternatives to antibiotics. Bacteriocins are ribosomally synthesized antimicrobial peptides produced by bacteria as a self-preservation method against competitors. Bacteriocins produced by Staphylococcus, also referred to as staphylococcins, have steadily shown great antimicrobial potential and are currently being considered promising candidates to mitigate the AMR menace. Moreover, several bacteriocin-producing Staphylococcus isolates of different species, especially coagulase-negative staphylococci (CoNS), have been described and are being targeted as a good alternative. This revision aims to help researchers in the search and characterization of staphylococcins, so we provide an up-to-date list of bacteriocin produced by Staphylococcus. Moreover, a universal nucleotide and amino acid-based phylogeny system of the well-characterized staphylococcins is proposed that could be of interest in the classification and search for these promising antimicrobials. Finally, we discuss the state of art of the staphylococcin applications and an overview of the emerging concerns.
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ARATA, JIRO. "Staphylococcus and staphylococcal infection. 1. Classification and properties of staphylococcus." Nishi Nihon Hifuka 50, no. 1 (1988): 108–11. http://dx.doi.org/10.2336/nishinihonhifu.50.108.

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Wei, Yuannan, Esha Sandhu, Xi Yang, Jie Yang, Yuanyuan Ren, and Xingjie Gao. "Bidirectional Functional Effects of Staphylococcus on Carcinogenesis." Microorganisms 10, no. 12 (November 28, 2022): 2353. http://dx.doi.org/10.3390/microorganisms10122353.

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As a Gram-positive cocci existing in nature, Staphylococcus has a variety of species, such as Staphylococcus aureus and Staphylococcus epidermidis, etc. Growing evidence reveals that Staphylococcus is closely related to the occurrence and development of various cancers. On the one hand, cancer patients are more likely to suffer from bacterial infection and antibiotic-resistant strain infection compared to healthy controls. On the other hand, there exists an association between staphylococcal infection and carcinogenesis. Staphylococcus often plays a pathogenic role and evades the host immune system through surface adhesion molecules, α-hemolysin, PVL (Panton-Valentine leukocidin), SEs (staphylococcal enterotoxins), SpA (staphylococcal protein A), TSST-1 (Toxic shock syndrom toxin-1) and other factors. Staphylococcal nucleases (SNases) are extracellular nucleases that serve as genomic markers for Staphylococcus aureus. Interestingly, a human homologue of SNases, SND1 (staphylococcal nuclease and Tudor domain-containing 1), has been recognized as an oncoprotein. This review is the first to summarize the reported basic and clinical evidence on staphylococci and neoplasms. Investigations on the correlation between Staphylococcus and the occurrence, development, diagnosis and treatment of breast, skin, oral, colon and other cancers, are made from the perspectives of various virulence factors and SND1.
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Slany, Michal, Martina Vanerkova, Eva Nemcova, Barbora Zaloudikova, Filip Ruzicka, and Tomas Freiberger. "Differentiation of Staphylococcus spp. by high-resolution melting analysis." Canadian Journal of Microbiology 56, no. 12 (December 2010): 1040–49. http://dx.doi.org/10.1139/w10-091.

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High-resolution melting analysis (HRMA) is a fast (post-PCR) high-throughput method to scan for sequence variations in a target gene. The aim of this study was to test the potential of HRMA to distinguish particular bacterial species of the Staphylococcus genus even when using a broad-range PCR within the 16S rRNA gene where sequence differences are minimal. Genomic DNA samples isolated from 12 reference staphylococcal strains ( Staphylococcus aureus , Staphylococcus capitis , Staphylococcus caprae , Staphylococcus epidermidis , Staphylococcus haemolyticus , Staphylococcus hominis , Staphylococcus intermedius , Staphylococcus saprophyticus , Staphylococcus sciuri , Staphylococcus simulans , Staphylococcus warneri , and Staphylococcus xylosus ) were subjected to a real-time PCR amplification of the 16S rRNA gene in the presence of fluorescent dye EvaGreen™, followed by HRMA. Melting profiles were used as molecular fingerprints for bacterial species differentiation. HRMA of S. saprophyticus and S. xylosus resulted in undistinguishable profiles because of their identical sequences in the analyzed 16S rRNA region. The remaining reference strains were fully differentiated either directly or via high-resolution plots obtained by heteroduplex formation between coamplified PCR products of the tested staphylococcal strain and phylogenetically unrelated strain.
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Navaratna, Maduwe A. D. B., Hans-Georg Sahl, and John R. Tagg. "Two-Component Anti-Staphylococcus aureusLantibiotic Activity Produced by Staphylococcus aureusC55." Applied and Environmental Microbiology 64, no. 12 (December 1, 1998): 4803–8. http://dx.doi.org/10.1128/aem.64.12.4803-4808.1998.

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ABSTRACT Staphylococcus aureus C55 was shown to produce bacteriocin activity comprising three distinct peptide components, termed staphylococcins C55α, C55β, and C55γ. The three peptides were purified to homogeneity by a simple four-step purification procedure that consisted of ammonium sulfate precipitation followed by XAD-2 and reversed-phase (C8 and C18) chromatography. The yield following C8 chromatography was about 86%, with a more-than-300-fold increase in specific activity. When combined in approximately equimolar amounts, staphylococcins C55α and C55β acted synergistically to kill S. aureus or Micrococcus luteus but not S. epidermidis strains. The N-terminal amino acid sequences of all three peptides were obtained and staphylococcins C55α and C55β were shown to be lanthionine-containing (lantibiotic) molecules with molecular weights of 3,339 and 2,993, respectively. The C55γ peptide did not appear to be a lantibiotic, nor did it augment the inhibitory activities of staphylococcin C55α and/or C55β. Plasmids of 2.5 and 32.0 kb are present in strain C55, and following growth of this strain at elevated temperature (42°C), a large proportion of the progeny failed to produce strong bacteriocin activity and also lost the 32.0-kb plasmid. Protoplast transformation of these bacteria with purified 32-kb plasmid DNA regenerates the ability to produce the strong bacteriocin activity.
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Iversen, Søren, Thor Bech Johannesen, Anna Cäcilia Ingham, Sofie Marie Edslev, Staffan Tevell, Emeli Månsson, Åsa Nilsdotter-Augustinsson, Bo Söderquist, Marc Stegger, and Paal Skytt Andersen. "Alteration of Bacterial Communities in Anterior Nares and Skin Sites of Patients Undergoing Arthroplasty Surgery: Analysis by 16S rRNA and Staphylococcal-Specific tuf Gene Sequencing." Microorganisms 8, no. 12 (December 12, 2020): 1977. http://dx.doi.org/10.3390/microorganisms8121977.

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The aim was to study alterations of bacterial communities in patients undergoing hip or knee arthroplasty to assess the impact of chlorhexidine gluconate soap decolonisation and systemic antibiotic prophylaxis. A Swedish multicentre, prospective collection of samples obtained from elective arthroplasty patients (n = 83) by swabbing anterior nares, skin sites in the groin and the site of planned surgery, before and after arthroplasty surgery, was analysed by 16S rRNA (V3-V4) gene sequencing and a complementary targeted tuf gene sequencing approach to comprehensively characterise alterations in staphylococcal communities. Significant reductions in alpha diversity was detected for both bacterial (p = 0.04) and staphylococcal (p = 0.03) groin communities after arthroplasty surgery with significant reductions in relative Corynebacterium (p = 0.001) abundance and Staphylococcus hominis (p = 0.01) relative staphylococcal abundance. In nares, significant reductions occurred for Staphylococcus hominis (p = 0.02), Staphylococcus haemolyticus (p = 0.02), and Staphylococcus pasteuri (p = 0.003) relative to other staphylococci. Staphylococcus aureus colonised 35% of anterior nares before and 26% after arthroplasty surgery. Staphylococcus epidermidis was the most abundant staphylococcal species at all sampling sites. No bacterial genus or staphylococcal species increased significantly after arthroplasty surgery. Application of a targeted tuf gene sequencing approach provided auxiliary staphylococcal community profiles and allowed species-level characterisation directly from low biomass clinical samples.
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ARATA, JIRO. "Staphylococcus and staphylococcal infections. 5. Toxins of Staphylococcus aureus and toxin related diseases." Nishi Nihon Hifuka 50, no. 5 (1988): 902–9. http://dx.doi.org/10.2336/nishinihonhifu.50.902.

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Skalka, B. "Antagonistic Effect of Staphylococcus hyicus and Staphylococcus chromogenes Exhibited on Staphylococcal Delta Hemolysin." Acta Veterinaria Brno 60, no. 1 (1991): 61–69. http://dx.doi.org/10.2754/avb199160010061.

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Edslev, Sofie Marie, Caroline Meyer Olesen, Line Brok Nørreslet, Anna Cäcilia Ingham, Søren Iversen, Berit Lilje, Maja-Lisa Clausen, et al. "Staphylococcal Communities on Skin Are Associated with Atopic Dermatitis and Disease Severity." Microorganisms 9, no. 2 (February 19, 2021): 432. http://dx.doi.org/10.3390/microorganisms9020432.

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The skin microbiota of atopic dermatitis (AD) patients is characterized by increased Staphylococcus aureus colonization, which exacerbates disease symptoms and has been linked to reduced bacterial diversity. Skin bacterial communities in AD patients have mostly been described at family and genus levels, while species-level characterization has been limited. In this study, we investigated the role of the bacteria belonging to the Staphylococcus genus using targeted sequencing of the tuf gene with genus-specific primers. We compared staphylococcal communities on lesional and non-lesional skin of AD patients, as well as AD patients with healthy controls, and determined the absolute abundance of bacteria present at each site. We observed that the staphylococcal community, bacterial alpha diversity, and bacterial densities were similar on lesional and non-lesional skin, whereas AD severity was associated with significant changes in staphylococcal composition. Increased S. aureus, Staphylococcus capitis, and Staphylococcus lugdunensis abundances were correlated with increased severity. Conversely, Staphylococcus hominis abundance was negatively correlated with severity. Furthermore, S. hominis relative abundance was reduced on AD skin compared to healthy skin. In conclusion, various staphylococcal species appear to be important for skin health.
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Dissertations / Theses on the topic "Staphylococcus"

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Raupelytė, Eglė. "Koaguliazei teigiamų stafilokokų išskyrimas iš gyvūnų augintinių." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2014~D_20140305_133815-68093.

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Darbo tikslas: nustatyti koaguliazei teigiamų stafilokokų paplitimą tarp gyvūnų augintinių. Darbo uždaviniai: 1. išskirti koaguliazei teigiamus stafilokokus iš gyvūnų augintinių nosies ertmės; 2. išskirti koaguliazei teigiamus stafilokokus iš gyvūnų augintinių tiesiosios žarnos; 3. identifikuoti išskirtas stafilokokų padermes; 4. įvertinti įvairių veiksnių įtaką stafilokokų paplitimui; 5. nustatyti išskirtų stafilokokų atsparumą antimikrobinėms medžiagoms. Darbo apimtis – 50 puslapių. Šiame darbe yra 6 lentelės bei 14 paveikslų. Magistro darbą sudaro 4 dalys. Pirmojoje dalyje apžvelgiami literatūros šaltiniai susiję su analizuojama tema, išskiriant koaguliazei teigiamų stafilokokų virulentiškumo veiksnius, atsparumą antimikrobinėms medžiagoms, sukeliamas ligas ir šių ligų gydymą. Aptariamas Staphylococcus aureus bei Staphylococcus pseudintermedius paplitimas ir paplitimą įtakojantys veiksniai. Antrojoje dalyje nurodyti tyrimo metodai, kuriais remiantis gauti duomenys tyrimų analizei. Trečiojoje dalyje analizuojami gauti tyrimo rezultatai pagal iškeltus uždavinius. Rezultatai pateikiami atsižvelgiant į statistinių duomenų patikimumą. Ketvirtoji dalis skirta literatūros apžvalgos ir tyrimo rezultatų skirtumų ir panašumų palyginimui. Tyrimo metu iš gyvūnų augintinių nosies ertmės ir tiesiosios žarnos išskirti Staphylococcus aureus bei Staphylococcus pseudintermedius. Nustatyta, kad koaguliazei teigiamų stafilokokų paplitimas gyvūnų augintinių tarpe priklauso nuo gyvūnų... [toliau žr. visą tekstą]
The The goal of the study: to determine prevalence of coagulase positive staphylococci in companion animals. The aim of the study: 1. to isolate coagulase positive staphylococci in nasal cavity of companion animals; 2. to isolate coagulase positive staphylococci in rectum of companion animals; 3. to identificate the isolated strains of staphylococci; 4. to evaluate risk factors for prevalence of staphylococci; 5. to determine antibiotic resistance in isolated staphylococci. The master study consists of 50 pages. It includes 6 tables and 14 pictures. The master study consist of 4 major chapters. The first chapter is dedicated to review of literature that is related with analized topic. This part includes coagulase positive staphylococci virulence factors, antibiotic resistance, diseases caused by staphylococci and treatment use. Furthermore chapter contains review of the prevalence and risk factors influenced the prevalence of Staphylococcus aureus and Staphylococcus pseudintermedius. The second chapter introduce with materials and methods, that were used in the research at this master study. In the third chapter the results of the research are presented. The results are presented according to the statistical reliability. The fourth chapter is the resemblance and similarity comparision of the literature review and master study research. In this master study Staphylococcus aureus and Staphylococcus pseudintermedius were isolated from nasal cavity and rectum of companion... [to full text]
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Bjertsjö, Rennermalm Anna. "Staphylococcal cell wall associated proteins : characteristics and host interactions /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-542-9/.

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Bes, Michèle. "Caractérisation de bactériophages de Staphylococcus epidermidis et Staphylococcus saprophyticus." Lyon 1, 1991. http://www.theses.fr/1991LYO10011.

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Les staphylocoques coagulase-negatifs (scn), bacteries commensales de la peau et des muqueuses sont frequemment isoles au cours d'infections graves principalement chez des patients immunodeprimes ou porteurs de materiel etranger. L'absence de systeme de lysotypie des scn permettant de caracteriser ces souches pathogenes et de les differencier des couches isolees comme contaminants, nous a conduit a isoler nos propres bacteriophages. Deux lots de phages ont ete isoles de s. Epidermidis et s. Saprophyticus et evalues dans un premier temps comme marqueurs epidemiologiques en terme d'activite lytique, de reproductibilite et de pouvoir discriminant. Le nombre de souches typables reste faible: 23% avec les phages de s. Epidermidis et 8% avec les phages de s. Saprophyticus. Cependant nos sytemes presentent une bonne specificite et reproductibilite. L'etude au microscope electronique a montre que ces phages appartenaient au groupe morphologique b1 (queue longue et non contractile, tete isometrique) defini par ackermann et eisenstark et a la famille des siphoviridae. Trois sous-groupes ont pu etre constitues en fonction des dimensions: -phages de s. Epidermidis, -phages de s. Saprophyticus, morphotype i phages de s. Saprophyticus morphotype ii. Une correlation etroite entre la morphologie, la structure antigenique et les caracteres des acides nucleiques est observee pour les phages de s. Saprophyticus. Les phages de s. Epidermidis presentent quant a eux une heterogeneite au niveau des adn (27 a 79% d'homologie). A l'issue de ce travail, deux nouvelles especes de phages de staphylococcus saprophyticus sont proposees: une premiere representee par les phages 1139, 1314, 1259 (type morphologique ii), la deuxieme representee par les phages 1154a et 1405 (type i) est originale par la petite taille des virions
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Nilsdotter, Åsa. "Coagulase-negative staphylococci in prosthetic hip infections /." Linköping : Univ, 2005. http://www.bibl.liu.se/liupubl/disp/disp2005/med902s.pdf.

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Lamers, Ryan Paul. "Evolutionary relationships among staphylococci and the prevention of Staphylococcus aureus nasal colonization." Doctoral diss., University of Central Florida, 2011. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/4782.

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Staphylococcus is a significant cause of human infection and mortality, worldwide. Currently, there are greater than 60 taxa within Staphylococcus, and nearly all are pathogenic. The collective potential for virulence among species of Staphylococcus heightens the overall clinical significance of this genus and argues for a thorough understanding of the evolutionary relationships among species. Within Staphylococcus, aureus is the most common cause of human infection, where nasal carriage of this bacterium is a known risk factor for autoinfection. The predisposition to infection by nasal carriers of S. aureus, and the ease with which strains are transferred between individuals, suggests that nasal carriage is a major vector for the transmission of virulent strains throughout the community. This hypothesis, however, has not been assessed in any great detail to identify the genetic relationships between clinical isolates of S. aureus and those strains being carried asymptomatically throughout the community. Also lacking within this field is a unified and robust estimate of phylogeny among species of Staphylococcus. Here, we report on a highly unified species phylogeny for Staphylococcus that has been derived using multilocus nucleotide data under multiple Bayesian and maximum likelihood approaches. Our findings are in general agreement with previous reports of the staphylococcal phylogeny, although we identify multiple previously unreported relationships. Regardless of methodology, strong nodal support and high topological agreement was observed with only minor variations in results between methods. Based on our phylogenetic estimates, we propose that Staphylococcus species can be evolutionarily clustered into 15 groups, and six species groups. In addition, our more defined phylogenetic analyses of S. aureus revealed strong genetic associations between both nasal carriage strains and clinical isolates. Genetic analyses of hypervariable regions from virulence genes revealed that not only do clinically relevant strains belong to identical genetic lineages as the nasal carriage isolates, but they also exhibited 100% sequence similarity within these regions. Our findings indicate that strains of S. aureus being carried asymptomatically throughout the community via nasal colonization are genetically related to those responsible for high levels of infection and mortality. Due to nasal carriage of S. aureus being a risk factor for autoinfection, standardized preoperative decolonization has become a major consideration for the prevention of nosocomial infection. Toward this end, we have identified the macrocyclic ?-defensin analogue RC-101 as a promising anti-S. aureus agent for nasal decolonization. RC-101 exhibited bactericidal effects against S. aureus in both epithelium-free systems, and ex vivo models containing human airway epithelia. Importantly, RC-101 exhibited potent anti-S. aureus activities against all strains tested, including USA300. Moreover, RC-101 significantly reduced the adherence, survival, and proliferation of S. aureus on human airway epithelia without any noted cellular toxicity or the induction of a proinflammatory response. Collectively, our findings identify RC-101 as a potential preventative of S. aureus nasal colonization.
ID: 030646199; System requirements: World Wide Web browser and PDF reader.; Mode of access: World Wide Web.; Thesis (Ph.D.)--University of Central Florida, 2011.; Includes bibliographical references (p. 140-159).
Ph.D.
Doctorate
Molecular Biology and Microbiology
Medicine
Biomedical Sciences
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Planchon, Stella. "Aptitude de Staphylococcus carnosus et Staphylococcus xylosus à former des biofilms." Phd thesis, Clermont-Ferrand 2, 2006. http://tel.archives-ouvertes.fr/docs/00/69/39/34/PDF/2006CLF21661.pdf.

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Staphylococcus xylosus et Staphylococcus carnosus sont utilisés comme ferments de salaisons. S. Xylosus est fréquemment isolé dans l'environnement des ateliers de transformation alimentaire alors que S. Carnosus l'est rarement. Ainsi, nous avons étudié la capacité de ces deux espèces à former des biofilms sur divers supports abiotiques. Les souches de S. Carnosus sont hydrophiles, adhèrent à des supports hydrophiles mais ne forment pas de biofilms. Certaines souches de S. Xylosus sont hydrophiles, d'autres moyennement hydrophobes et elles forment des biofilms quelque soit le support. S. Xylosus C2a, choisie comme souche d'étude, forme des biofilms denses avec des agrégats intercelluaires séparés par des canaux et englués dans une matrice constituée de polysaccharides dont la synthèse ne semble pas liée au gène icaA. Nous avons mis en evidence les gènes atl et bap codant des protèines de surface impliquées dans la formation de biofilm chez S. Aureus. Pour étudier l'ensemble des protéines de surface impliquées, nous avons développé une méthode d'analyse des protéines pariétales et membranaires. Un total de 101 protéines a été identifié dont 51 sont prédites comme protéines de surface et seulement 9 sont cmmunes aux deux fractions. La comparaison des profils protéiques des fractions pariétales, membranaires et intracellulaires a révélé une expression différentielle de 115 protéines dont 74 sont surexprimées en mode sessile et 41 en planctonique. Cette étude a révélé la modification de nombreuses voies métabolliques. Leur analyse permettra de mieux appréhender les mécanismes mis en jeu par S. Xylosus lors de sa croissance en biofilm
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Ho, Moon-lung, and 何滿龍. "Universal screening for methicillin-resistant staphylococccus [i.e. staphylococcus] aureus control by hospitals: a systematic review." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B46936245.

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Cho, Seung-Hak. "Epidemiologische und molekulare Untersuchungen zur Biofilmbildung in Staphylococcus epidermidis und Staphylococcus aureus." Doctoral thesis, [S.l.] : [s.n.], 2001. http://deposit.ddb.de/cgi-bin/dokserv?idn=96419127X.

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Juodžentytė, Renalda. "Staphylococcus aureus ir Staphylococcus pseudintermedius išskyrimas iš gyvūnų augintinių ir jų savininkų." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2014~D_20140305_133603-55635.

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Šio darbo tikslas - Staphylococcus aureus ir Staphylococcus pseudintermedius išskyrimas iš gyvūnų augintinių, jų savininkų ir antimikrobinių medžiagų atsparumo nustatymas. Darbo uždaviniai: 1. Išskirti stafilokokus iš gyvūnų augintinių. 2. Išskirti stafilokokus iš gyvūnų augintinių savininkų. 3. Identifikuoti koaguliazei teigiamus stafilokokus. 4. Įvertinti įvairių veiksnių įtaka šunų nosies ertmės ir tiesiosios žarnos mikroflorai. 5. Įvertinti įvairių veiksnių įtaka gyvūnų augintinių savininkų nosies ertmės mikroflorai. 6. Nustatyti atsparumą antimikrobinėms medžiagoms. Iš viso paimti 123 mėginiai, iš jų 82 mėginiai paimti iš šunų laikomų namuose ir lauke, ir 41 mėginys iš jų savininkų. Mėginiai mikrobiologiniam tyrimui buvo imami į transportines terpes TRANSWAB® (naudojama pernešimo terpė aerobams ir anaerobams išskirti (Amies, Liofilchem, Italija)). Mikroorganizmų išskirta iš 37 (30,1 proc.) mėginių. Po vieną mikroorganizmų rūšį nustatyta 33 (89,1 proc.) mėginiuose. Po dvi mikroorganizmų rūšis (mišri infekcija), nustatyta 4 (10,9 proc.) mėginiuose. Iš šunų nosies ertmės ir tiesiosios žarnos paimto 41 mėginio mikroorganizmai buvo išskirti iš 27 (59,3 proc.). Staphylococcus pseudintermedius sudarė 32,4 proc. išskirtų mikroorganizmų, Staphylococcus aureus – 12,2 proc., Bacillus spp. – 14,7 proc. Iš šunų savinikų nosies ertmės paimto 41 mėginio mikroorganizmai buvo išskirti iš 16 (55,9 proc.) mėginių. Staphylococcus aureus sudarė 36,5 proc. išskirtų mikroorganizmų... [toliau žr. visą tekstą]
The objective of the research: Staphylococcus aureus and Staphylococcus pseudintermedius isolation from a pet and their owners, and determine the resistance of isolates to antimicrobial agent. Tasks of the research: 1. To isolate staphylococci from pet. 2. To isolate staphylococci from pet owners. 3. To identify coagulase-positive staphylococci. 4. Evaluate the influence of canine nasal and rectal flora. 5. Evaluate the influence of the pet owners nasal cavity flora. 6. To determine the resistance of isolates to antimicrobial agent. 41 samples of dogs and 41 from humans were investigated. Total take 123 samples, including 82 samples were taken from dogs kept in the home and outdoors, and 41 samples of their owners. Samples for microbiological analysis were collected in transport medium TRANSWAB ® (used to transport medium for aerobes and anaerobes release (Amies, Liofilchem, Italy)). Microorganisms were identified in 37 (30.1 percent.) samples. Single type of microorganisms were identified in 33 (89.1 percent) samples. Two types of microorganisms (mixed infection) were identified in 4 (10.9 percent) samples. In dogs, nasal and rectal were taken 41 samples. Microorganisms were identified in 27 (59.3 percent) samples. Staphylococcus pseudintermedius accounted 32.4 percent of identified microorganisms, Staphylococcus aureus – 12.2 percent, Bacillus spp. – 14.7 percent. Dogs owners nasal were taken 41 samples. Microorganisms were identified in 16 (55.9 percent) samples... [to full text]
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BARRIERE, CHARLOTTE. "Caracterisation des superoxyde dismutases et catalases de staphylococcus xylosus et staphylococcus carnosus." Clermont-Ferrand 2, 2001. http://www.theses.fr/2001CLF22282.

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Staphylococcus xylosus et staphylococcus carnosus sont deux especes a gram-positif, anaerobies facultatives, utilisees comme ferments dans les saucissons. Ils modulent la nature et le niveau des composes volatils issus de l'oxydation des acides gras. Leurs superoxyde dismutases (sods) et leurs catalases ont ete caracterisees afin de determiner leur pouvoir antioxydant. S. Xylosus c2a possede une seule sod proche des mnsods. Le gene codant (sod) a ete clone et sequence et deux promoteurs fonctionnels ont ete identifies en amont. L'expression du gene sod, etudiee a l'aide de fusions transcriptionnelles sod-lach, n'est pas modifiee par le paraquat ou le manganese, mais, elle est induite en phase stationnaire dans un milieu complexe. L'analyse du mutant sod, revele un role protecteur de la sod face a un stress oxydant. La sequence nucleotidique du gene kata de s. Xylosus c2a, codant une catalase proche des catalases monofonctionnelles, a ete determinee. L'expression du gene kata, etudiee a l'aide d'une fusion transcriptionnelle kata-lach, est induite, en phase stationnaire, par l'oxygene et le peroxyde d'hydrogene (h 2o 2). Elle est reprimee par le fer et surtout par le manganese. La presence d'une boite perr putative en amont du gene suggere une possible regulation par perr. Le mutant kata garde une activite catalase elevee revelant que kata n'est pas la principale catalase chez s. Xylosus c2a. En revanche, kata est essentiel pour une resistance optimale a l'h 2o 2 s. Xylosus c2a inhibe l'oxydation de l'acide linoleique. Sa sod et sa catalase kata contribuent a limiter cette oxydation. S. Carnosus 833 semble posseder une seule sod et une seule catalase dont les conditions de synthese semblent proches de celles de s. Xylosus c2a. La sod de s. Carnosus 833 presente de fortes similitudes de sequence avec celle de s. Xylosus c2a.
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Books on the topic "Staphylococcus"

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Fey, Paul D. Staphylococcus epidermidis: Methods and protocols. New York: Humana Press, 2014.

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V, Smirnov V., Vershigora A. E, and Instytut mikrobiolohiï im. virusolohiï D.K. Zabolotnoho., eds. Stafilokokk: Biologicheski aktivnye substant͡s︡ii, immunnyĭ otvet na antigeny. Kiev: Nauk. dumka, 1988.

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Rice, Kelly C., ed. Staphylococcus aureus. New York, NY: Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1550-8.

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Fey, Paul D., ed. Staphylococcus Epidermidis. Totowa, NJ: Humana Press, 2014. http://dx.doi.org/10.1007/978-1-62703-736-5.

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Bagnoli, Fabio, Rino Rappuoli, and Guido Grandi, eds. Staphylococcus aureus. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-72063-0.

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Nakane, Akio, and Krisana Asano, eds. Staphylococcus aureus. Singapore: Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-9428-1.

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B, Crossley Kent, ed. Staphylococci in human disease. 2nd ed. Chichester, West Sussex: Wiley-Blackwell, 2010.

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A, Ala'Aldeen Dlawer A., and Hiramatsu Keiichi 1949-, eds. Staphylococcus aureus: Molecular and clinical aspects. Chichester, U.K: Horwood Pub., 2004.

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D, Freeman-Cook Kevin, ed. Staphylococcus aureus infections. Philadelphia: Chelsea House Publishers, 2005.

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Freeman-Cook, Lisa. Staphylococcus aureus infections. Edited by Freeman-Cook Kevin D, Alcamo I. Edward, and Heymann David L. Philadelphia: Chelsea House Publishers, 2006.

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Book chapters on the topic "Staphylococcus"

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Hermans, K., L. A. Devriese, and F. Haesebrouck. "Staphylococcus." In Pathogenesis of Bacterial Infections in Animals, 75–89. Oxford, UK: Wiley-Blackwell, 2010. http://dx.doi.org/10.1002/9780470958209.ch5.

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Zhang, Mingjuan Lisa. "Staphylococcus." In Encyclopedia of Ophthalmology, 1. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-35951-4_709-1.

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Zhang, Mingjuan Lisa. "Staphylococcus." In Encyclopedia of Ophthalmology, 1672. Berlin, Heidelberg: Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-540-69000-9_709.

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Thapaliya, Dipendra. "Staphylococcus." In Handbook of Foodborne Diseases, 215–22. Boca Raton : Taylor & Francis, [2019] | Series: Food microbiology series | “A CRC title, part of the Taylor & Francis imprint, a member of the Taylor & Francis Group, the academic division of T&F Informa plc.”: CRC Press, 2018. http://dx.doi.org/10.1201/b22030-20.

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Novick, Richard. "Staphylococcus." In Bacillus subtilis and Other Gram-Positive Bacteria, 17–33. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555818388.ch2.

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Rodríguez, Mar, Alicia Rodríguez, María Jesús Andrade, Elena Bermúdez, and Juan José Córdoba. "Staphylococcus." In Laboratory Models for Foodborne Infections, 209–21. Boca Raton : CRC Press/Taylor & Francis, 2017. | Series: Food microbiology series: CRC Press, 2017. http://dx.doi.org/10.1201/9781315120089-13.

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Parija, Subhash Chandra. "Staphylococcus." In Textbook of Microbiology and Immunology, 339–54. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-3315-8_25.

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Nakane, Akio, and Phawinee Subsomwong. "Immune Response to Staphylococcus aureus." In Staphylococcus aureus, 151–86. Singapore: Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-9428-1_5.

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Becker, Karsten. "Colonization and Persistence Strategies of Staphylococcus aureus." In Staphylococcus aureus, 1–40. Singapore: Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-9428-1_1.

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Hu, Dong-Liang, Hisaya K. Ono, Shaowen Li, and Rendong Fang. "Exotoxins of Staphylococcus aureus." In Staphylococcus aureus, 81–117. Singapore: Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-9428-1_3.

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Conference papers on the topic "Staphylococcus"

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Kiranasari, Ariyani, Angela Bonita, Elizabeth Melina, Kevin Winston, Naivedh Baht, Nathania Sutandi, Beti Ernawati Dewi, Ika Ningsih, and Fithriyah Sjatha. "Antibacterial Activity of Several Indonesian Endemic Plants against Staphylococcus epidermidis, Staphylococcus aureus and Methicillin-resistant Staphylococcus aureus." In Bromo Conference, Symposium on Natural Products and Biodiversity. SCITEPRESS - Science and Technology Publications, 2018. http://dx.doi.org/10.5220/0008359501780182.

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Cristina, Gisele Pereira Rodrigues e. Lilia, LILIA CRISTINA A. G. DE PAULA, and GISELE PREIRA RODRIGUES. "STAPHYLOCOCCUS AUREUS NO AMBIENTE HOSPITALAR." In IV Congresso Brasileiro de Ciências Biológicas On-line. Revista Multidisciplinar de Educação e Meio Ambiente, 2023. http://dx.doi.org/10.51189/conbracib2023/16933.

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Saptana, Yosefin Ida, Riski Sulistiarini, and Rolan Rusli. "AKTIVITAS ANTIBAKTERI GEL EKSTRAK KECOMBRANG (ETLINGERA ELATIOR) TERHADAP BAKTERI STAPHYLOCOCCUS AUREUS DAN STAPHYLOCOCCUS EPIDERMIDIS." In Mulawarman Pharmaceuticals Conferences. Fakultas Farmasi, Universitas Mulawarman, Samarinda, 2015. http://dx.doi.org/10.25026/mpc.v2i1.51.

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Himelbloom, B. H. "Staphylococcus aureus concerns in smoked fish." In International Smoked Seafood Conference. Alaska Sea Grant, University of Alaska Fairbanks, 2008. http://dx.doi.org/10.4027/isscp.2008.03.

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Adams, Kelly M., Valsamma Abraham, Daniel Spielman, Noam Cohen, Jay K. Kolls, and James L. Kreindler. "Pendrin Expression In Staphylococcus Aureus Pneumonia." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a3532.

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Blajan, Marius, Ahmad Guji Yahaya, Jaroslav Kristof, Tomohiro Okuyama, and Kazuo Shimizu. "Inactivation of Staphylococcus Aureus by Microplasma." In 2021 IEEE Industry Applications Society Annual Meeting (IAS). IEEE, 2021. http://dx.doi.org/10.1109/ias48185.2021.9677085.

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Jamil, Alia Hussein, Ali Abdulhussien, and Mohammad Alsharifi. "The anti-biofilm activity of lemon oil against methicillin resistance of Staphylococcus aureus and Staphylococcus haemolyticus." In 3RD INTERNATIONAL SCIENTIFIC CONFERENCE OF ALKAFEEL UNIVERSITY (ISCKU 2021). AIP Publishing, 2022. http://dx.doi.org/10.1063/5.0067569.

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Caraman, Mariana, Larisa Cremeneac, Roman Moscalic, Oleg Cojusneanu, and Cristina Mihaela Rimbu. "Diagnosticul, tratamentul și profilaxia infecțiilor stafilococe la iepuri." In Scientific and practical conference with international participation: "Management of the genetic fund of animals – problems, solutions, outlooks". Scientific Practical Institute of Biotechnologies in Animal Husbandry and Veterinary Medicine, 2023. http://dx.doi.org/10.61562/mgfa2023.50.

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The aim of the work was to establish the diagnosis, effective measures for treatment and prophylaxis of staphylococcal infections at rabbits. As research objects served 25 cadavers of young rabbits and 96 breeding females. The diagnosis focused on the clinical examination of the herd, the morphopathological appearance of the corpses, bacteriological studies of the biomaterial taken and the isolation of the pathogenic agent. As a result of bacteriological investigations, Staphylococcus aureus was isolated from the pathological material. The treatment was established as a result of determining the sensitivity of the pathogen to antibiotics. For the prophylaxis of staphylococcal infections, it was recommended to observe the rules of hygiene, feeding (quality fodder and balanced ration), the plan of periodic disinfection and deratization. Also, performing daily clinical examinations of the herd, identifying sick animals with skin lesions, mamitis, rhinitis, auricular scabies; removal of spiky plants from feed and litter.
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Omar Mohammed, Mohammed Shaymaa, Nicoleta Radu, Verginica Schroder, Rodica Roxana Constantinescu, and Narcisa Babeanu. "Antimicrobial Properties of the Bioproducts Formulated with Chitosan and Collagen." In The 9th International Conference on Advanced Materials and Systems. INCDTP - Leather and Footwear Research Institute (ICPI), Bucharest, Romania, 2022. http://dx.doi.org/10.24264/icams-2022.ii.17.

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Three types of formulations (stable suspensions) based on collagen, chitosan, limonene and an imidazole derivative were studied through in vitro tests, from the point of view of antimicrobial activity. The results obtained on 4 standardized microorganisms, namely Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, Staphylococcus aureus MRSA, Candida albicans, demonstrated that most of the obtained bioproducts have a local effect (inhibition diameters below 15 mm are obtained) and moderate effect (inhibition diameters located under 20 mm), except bioproducts containing collagen, chitosan, limonene and an imidazole derivative (antibiotic reagent) in mass ratio Col:Chit:Lim:CT=1:1:1:0.1, Col:Chit:Lim:CT=1:1:0:0.1 which exhibit a significant antimicrobial effect on Staphylococcus aureus and Staphylococcus aureus MRSA. These two formulations also exhibit significant antimicrobial effects for Candida albicans, for which the average inhibition diameters obtained are greater than 34 mm.
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Apolinário, Joelma Maria dos Santos da Silva. "CARACTERÍSTICAS CLASSIFICAÇÃO E PATOGENICIDADE DO STAPHYLOCOCCUS AUREUS." In I Congresso Nacional de Microbiologia Clínica On-Line. Revista Multidisciplinar em Saúde, 2021. http://dx.doi.org/10.51161/rems/1211.

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Introdução: O S. aureus trata-se de uma bactéria Gram-positiva onde suas células têm forma de cocos, apresentam-se frequentemente agrupados em cacho e são imóveis. Em condições favoráveis, produz toxinas – enterotoxinas – que são o agente responsável pela intoxicação alimentar. Os fatores de patogenicidade associados a bactéria são; adesinas e formação de biofilme. Outros fatores como invasinas (proteases, lipases) e toxinas, também tem sido bastante estudados. Considerando a habilidade das bactérias produzirem o filme extracelular in vitro, propõe-se uma marca de patogenicidade associando ser um organismo virulento. Objetivo: Avaliar seus fatores características e patogenicidade bem como pesquisar a sua capacidade produtora de enterotoxina. Metodologia: O presente trabalho configurou-se com um estudo de caso através da revisão sistemática da literatura, que possibilitou a construção de referencial teórico sobre assuntos que estão relacionados ao tema em questão, utilizando dados de artigos científicos das plataformas digitais PubMed (National Library of Medicine) e SciELO (Scientific Electronic Library Online). Resultados: As espécies de Staphylococcus podem ser classificadas em dois grupos de acordo com a presença ou ausência da enzima coagulase. Assim, as espécies que possuem a enzima são denominadas coagulase positiva, sendo o Staphylococcus aureus a única espécie desse grupo, e as espécies que não possuem são chamadas de estafilococos coagulase negativa. Conclusão: As enterotoxinas produzidas por S. aureus podem estar relacionadas com o agravamento das doenças causadas pelo micro-organismo, além da sua habilidade de causar intoxicação alimentar, dessa forma constata-se que a bactéria é um dos principais patógenos de maior patogenicidade alta ocorrência e morbidade das infecções por este ocasionado.
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Reports on the topic "Staphylococcus"

1

Leitner, Gabriel, and Naomi Balaban. Novel Immunotherapeutic Agent for the Treatment and Prevention of Staphylococcal Mastitis in Dairy Cows. United States Department of Agriculture, January 2009. http://dx.doi.org/10.32747/2009.7709880.bard.

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Staphylococci are the most common and costly mammary disease of dairy cattle worldwide. TRAP, a membrane associated 167AA protein, is highly conserved among staphylococci. The aims of this study were to test the safety and efficacy of recombinant TRAP (rTRAP) vaccine in dairy animals. The vaccine was safe as 2-3 subcutaneous injections of rTRAP (54–100μg) with adjuvant ISA 206 to cows and goats did not lead to any abnormal symptoms of sensitivity to the vaccine. The rTRAP vaccine was immunogenic and caused the induction of a humoral immune response that remained high for at least 160 days post second immunization. rTRAP vaccine also elicited a cell-mediated immune response (memory CD4+ and CD8+ T cells), as determined by lymphocyte proliferation assays. The rTRAP vaccine was efficacious as at parturition, only 13.5% heifers in the immunized group were infected with Staphylococcus chromogenes as compared to 42.9% in the non immunized group. Additionally, when cows were immunized in mid-lactation, the difference between somatic cell count (SCC) in immunized and control animals was profound (45±7 vs. 470±194, respectively). At the same time, the difference in milk yield was also evident (48.3±1.4 vs. 44.3±0.9 l/day, respectively). Put together, these studies indicate the value of the rTRAP vaccine in preventing new udder infections by staphylococci, which significantly lead to lowered SCC and some increase in milk yield. TRAP is conserved among all strains and species and is constitutively expressed in any strain of S. aureus or CNS tested so far, including those isolated from cows. TRAP may thus serve as a universal anti-staphylococcus vaccine.
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Leitner, Gabriel, and Naomi Balaban. Novel Immunotherapeutic Agent for the Treatment and Prevention of Staphylococcal Mastitis in Dairy Cows. United States Department of Agriculture, January 2009. http://dx.doi.org/10.32747/2009.7695866.bard.

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Staphylococci are the most common and costly mammary disease of dairy cattle worldwide. TRAP, a membrane associated 167AA protein, is highly conserved among staphylococci. The aims of this study were to test the safety and efficacy of recombinant TRAP (rTRAP) vaccine in dairy animals. The vaccine was safe as 2-3 subcutaneous injections of rTRAP (54–100μg) with adjuvant ISA 206 to cows and goats did not lead to any abnormal symptoms of sensitivity to the vaccine. The rTRAP vaccine was immunogenic and caused the induction of a humoral immune response that remained high for at least 160 days post second immunization. rTRAP vaccine also elicited a cell-mediated immune response (memory CD4+ and CD8+ T cells), as determined by lymphocyte proliferation assays. The rTRAP vaccine was efficacious as at parturition, only 13.5% heifers in the immunized group were infected with Staphylococcus chromogenes as compared to 42.9% in the non immunized group. Additionally, when cows were immunized in mid-lactation, the difference between somatic cell count (SCC) in immunized and control animals was profound (45±7 vs. 470±194, respectively). At the same time, the difference in milk yield was also evident (48.3±1.4 vs. 44.3±0.9 l/day, respectively). Put together, these studies indicate the value of the rTRAP vaccine in preventing new udder infections by staphylococci, which significantly lead to lowered SCC and some increase in milk yield. TRAP is conserved among all strains and species and is constitutively expressed in any strain of S. aureus or CNS tested so far, including those isolated from cows. TRAP may thus serve as a universal anti-staphylococcus vaccine.
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Sordillo, Lorraine, Don Wojchowski, Gary Perdew, Arthur Saran, and Gabriel Leitner. Identification of Staphylococcus aureaus Virulence Factors Associated with Bovine Mastitis. United States Department of Agriculture, February 2001. http://dx.doi.org/10.32747/2001.7574340.bard.

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Staphylococcus aureus is a major cause of mastitis in dairy cattle. The organism is able to adhere to and penetrate mammary epithelium, forming deep seated abscesses that result in chronic infections. This study was based on the observation that certain genotypes of S. aureus are isolated more frequently from field cases of bovine mastitis than others and the most prevalent genotypes of S. aureus have an increased ability to resist neutrophil phagocytosis and killing compared to the rare variants. It was hypothesized that these predominating genotypes differentially express virulence factors that allow them to overcome or suppress essential host defense mechanisms and successfully colonize mammary parenchyma. The overall objective of this study was to determine the mechanisms by which predominating S. aureus genotypes were able to resist mammary gland defense mechanisms. The following specific aims were accomplished to address the overall objectives of this project: 1. Analyze and compare cell surface and secreted protein profiles of common and rare S. aureus genotypes isolated from field cases of bovine mastitis. 2. Purify and sequence selectively synthesized proteins unique to the most prevalent genotypes of S. aureus . 3. Determine the in vitro effects of isolated proteins on essential host defense mechanisms. Results from each specific aim showed that these redominating genotypes differentially express factors that may allow them to overcome or suppress essential host defense mechanisms and successfully colonize mammary parenchyma. Using complementary approaches, both the US and Israeli teams identified differentially expressed S. aureus factors that were positively correlated with virulence as determined by the ability to modify host immune cell responses and increase disease pathogenesis. Several candidate virulence factors have ben identified at both the molecular (US team) and protein (Israeli team) levels. Components of the phosphotransferase system were shown to be differentially expressed in prevalent strains of S. aureus and to modify the growth potential of these strains in a milk microenvironment. Evidence provided by both the Israeli and US teams also demonstrated a potential role of Staphylococcal enterotoxins in the pathogenesis of mastitis. Certain enterotoxins were shown to directly affect neutrophil bactericidal activities which can profoundly affect the establishment of new intramammary infections. Other evidence suggests that S. aureus superantigens can suppress mammary defenses by enhancing lymphoid suppressor cell activity. Collectively, these data suggest that unique factors are associated with predominating S. aureus genotypes that can affect in vitro and in vivo virulence as related to the pathogenesis of bovine mastitis. The potential development of a subunit mastitis vaccine which incorporates only relevant antigenic determinants has not been investigated in depth. Experiments outlined in this proposal has identified putative virulence factors which contribute to the pathogenesis of S. aureus mastitis and which may be used to formulate an efficacious subunit mastitis vaccine. Results from these studies may lead to the development of new methods to prevent this costly disease, providing a viable alternative to less effective mastitis control procedures based on chemotherapy.
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Cheng, Xin, Juntong Zhou, Fan Yuan, Jingxin Ma, Shuilong Guo, and Jianrong Su. Diagnostic Value of BHI-V4 for Heterogeneous and Vancomycin-Intermediate Staphylococcus aureus Isolates. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, December 2023. http://dx.doi.org/10.37766/inplasy2023.12.0069.

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Spencer, Jessica, and Uzo Chukwuma. Methicillin-Resistant Staphylococcus aureus (MRSA) Infections in the Department of Defense (DOD): Annual Summary 2013. Fort Belvoir, VA: Defense Technical Information Center, January 2015. http://dx.doi.org/10.21236/ada612614.

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Timms, Leo L., and Phil Sears. Field Trial Evaluation of Extended Pirlimycin Therapy With or Without Vaccination for Staphylococcus Aureus Mastitis. Ames (Iowa): Iowa State University, January 2004. http://dx.doi.org/10.31274/ans_air-180814-981.

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Ju, Mohan, Yueying Huang, Xiaofeng Xu, Yiyi Qian, Yingmin Bi, Shuang Liu, Xiangyu Li, Shuaiyue Dong, Jinyi Yuan, and Dongfang Lin. Predictors of mortality in patients with Methicillin-resistant Staphylococcus aureus bloodstream infection: A meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, February 2021. http://dx.doi.org/10.37766/inplasy2021.2.0082.

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Miari, Zeina. Screening of Methicillin-Resistant Staphylococcus pseudintermedius Isolates for the Presence of Resistance to the Topical Antimicrobial Mupirocin. Ames (Iowa): Iowa State University, December 2023. http://dx.doi.org/10.31274/cc-20240624-1263.

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Leas, Brian F., David A. Pegues, and Nikhil K. Mull. Active Surveillance Culturing of Clostridioides difficile and Multi-Drug Resistant Organisms: Methicillin-Resistant Staphylococcus aureus, Carbapenem-Resistant Enterobacterales, and Candida auris. Agency for Healthcare Research and Quality (AHRQ), May 2024. http://dx.doi.org/10.23970/ahrqepc_mhs4culturing.

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Scheier, Thomas, Xiaomei Yao, John Eikelboom, Silvio Brugger, Dominik Mertz, and Peter Schreiber. Efficacy of Staphylococcus aureus eradication at hospital admission on reduction of any infections within 90 days – a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, May 2024. http://dx.doi.org/10.37766/inplasy2024.5.0015.

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