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Feng, Xiaoqi. "Cell specification and proliferation during stamen development in Arabidopsis Thaliana." Thesis, University of Oxford, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.540240.
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Ethington, Kalene Mears. "Developmental Stages Associated with Organizational Learning: An Instrument Development Study." BYU ScholarsArchive, 2019. https://scholarsarchive.byu.edu/etd/8287.
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Background: Previous research has identified four distinct developmental stages associated with organizational learning in high-performing hospital units: identity and ownership, team and respect, accountability and support, and reliability and sustainability. We designed a research instrument to measure these constructs. The purpose of this thesis was to establish the content and predictive validity of this instrument.Methods: The Organizational Learning Development Instrument (OLDI) consists of a total of 35 items in Likert-scale format. Item-level and instrument-level content validity were assessed using three cycles of cognitive interviewing with 28 nurses, and eight expert ratings. The OLDI was administered to nurses in Magnet® hospitals via a web-based survey. National Database of Nursing Quality Indicators (NDNQI) and Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) reports were used for comparison of hospital performance. Predictive validity was tested using multiple linear regression. Based on a power analysis for multiple linear regression, reaching 80% power, with a medium effect size of 0.15, an alpha of 0.05, and five predictor variables, the target sample size was 92 hospital units.Results: Results from 63 inpatient units in 11 Magnet® hospitals were used. The scale- level content validity for this instrument was 0.95 and item-level content validity index scores ranged from 0.86 to 1.0, suggesting excellent content validity. No significant relationships were found between OLDI results and NDNQI measures. Significant correlations (P<.05) were found between several OLDI constructs and HCAHPS composites.Discussion: Correlations with HCAHPS scores help validate the OLDI, as well as the theory underlying the instrument. The OLDI may not have predicted NDNQI measures due to a lack of instrument sensitivity or because NDNQI results are strongly influenced by other factors. Nurse managers can use the OLDI to predict unit performance related to patient satisfaction and to determine actions that may improve unit performance. Replicating this study with a larger sample size and more diverse hospital performance and more uniform unit type could further validate this instrument.
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Ноздрунов, Володимир Андрійович. "The Stages of Web Application Development." Thesis, Київський національний університет технологій та дизайну, 2017. https://er.knutd.edu.ua/handle/123456789/7378.
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McKechnie, Allan. "The use of developmental stages as a model for addressing and assessing spiritual formation and maturity." Theological Research Exchange Network (TREN), 2008. http://www.tren.com/search.cfm?p046-0069.
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McKechnie, Allan D. "The use of developmental stages as a model for addressing and assessing spiritual formation and maturity." St. Paul, MN : Bethel Seminary, 2008. http://dx.doi.org/10.2986/tren.046-0069.
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Fisher, W. D., and E. J. Pegelow. "Heat Units and Stages of Plant Development." College of Agriculture, University of Arizona (Tucson, AZ), 1986. http://hdl.handle.net/10150/219831.
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Harrison, Andrew J. "The development and application of biomechanical analysis techniques for evaluation of developmental stages in vertical jump." Thesis, University of Salford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.265526.
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Teixeira, Rita. "Developmental studies of cytoplasmic male-sterile Brassica napus lines /." Uppsala : Dept. of Plant Biology and Forest Genetics, Swedish University of Agricultural Sciences, 2005. http://epsilon.slu.se/200508.pdf.
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Civan, Isilay. "Assessment and enhancement of decision-making models used for the pre-development stages of office developments in turkey." Diss., Texas A&M University, 2003. http://hdl.handle.net/1969.1/5809.
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Real estate development involves many complex, dynamic, and uncertain elements. In the pre-development stage, greater uncertainties result from the fact that the space being considered has not yet been created. Considering both the inherent characteristics of the real estate and the inefficiency of the market it operates in, any aid in the investment decision process is believed to add to the quality of the end product. This being the case, most, if not all, of the development companies make office development decisions using some kind of a procedure in the pre-development stage. However low occupancy rates and long payback periods that are being faced, even by the most recently completed Class A office projects in Turkey, show that there are serious deficiencies in these applied procedures and that they lack the necessary and important components of project feasibility analysis, which are basically the market and financial feasibility analysis, that needs to be applied in the pre-development stage of the office development process. That is why this studyâÂÂs purpose is to explore and identify the deficiencies of the decision-making models currently used by Turkish real estate development companies in the pre-development stage of office development projects and to recommend necessary additions and/or deletions for the enhancement of these company models. To do so, this research involved interviews of ten office developers to identify their go/no-go decision processes in evaluating office developments in Istanbul, Turkey. The study has found that developers tend to fall under three different groups, each following different models: Group I includes exclusively construction companies, Group II includes mixed companies and Group III includes exclusively real estate investment companies. Furthermore, the research has found that similarities and differences among these three groups involve the following: While investment companies seek opportunities based on market research, decisions by construction companies are driven by the availability of land swaps. All three groups emphasize land availability and related title and land-use issues. Although unit-sale continues, there is a gradual shift to income property with the aid of improvement in the financial market, which is also reflected in the decision-making models being used.
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Dougherty, Jennifer L. "Impact of Child-Centered Play Therapy on Children of Different Developmental Stages." Thesis, University of North Texas, 2006. https://digital.library.unt.edu/ark:/67531/metadc5287/.
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The purpose of this study was to determine the impact of child-centered play therapy on children of Piaget's preoperational and concrete operations developmental stages. Piaget's assertions about the contributions of play to cognitive, affective, and social development have provided a basis for the theoretical rationale for the use of play as a therapeutic intervention. The impact of child-centered play therapy was measured by a decrease in parent-child relationship stress as measured by scores on the Child Domain, Parent Domain, and Total Stress Score of the Parenting Stress Index. This study utilized a three wave repeated measures ANOVA design to analyze the impact of child-centered play therapy on children between the ages of 3-8 who received 19-23 individual child-centered play therapy sessions. A pretest, approximate midpoint, and posttest administration was collected for use in the analysis. The population study comprised 24 children referred to the Child and Family Resource Clinic on the University of North Texas campus. Participating children were divided into two treatment groups based on their age at the time of treatment. The preoperational development treatment group consisted of 12 children aged of 3-6 years and the concrete operations development treatment group consisted of children aged 7-8 years. Nine hypotheses were tested using three wave repeated measures ANOVA and eta squared. The results of this study tentatively support the impact of child-centered play therapy with children of both the preoperational and concrete operations developmental stages. The data indicates a statistically significant difference in the impact of child-centered play therapy for children of different developmental stages.
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Marais, Susara. "Characterization of the early stages in biofilm development." Thesis, Stellenbosch : Stellenbosch University, 2004. http://hdl.handle.net/10019.1/49880.
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Thesis (MSc)--Stellenbosch University, 2004.ENGLISH ABSTRACT: Complex biofilm communities have extensively been studied in the past. Less work has been done on the early stages of biofilm formation. This study aimed to assess initial colonization patterns of biofilms on different surfaces and under different environmental conditions with application of novel methods describing biofilm surface profiles. Biofilms were cultivated on glass, polyvinylchloride (PVC) and polished stainless steel. Results from microscopy, followed by mathematical analysis and contact angle measurements proved that glass was the most appropriate substrate for this study. More extensive extracellular polymeric substances (EPS) production and apparently less cell attachment were observed on PVC and polished stainless steel surfaces. Two different series of experiments were conducted where biofilms were cultivated on the glass. Biofilm morphology was analysed under various conditions of temperature and nutrient concentration. Different temperature conditions were 8°C, 22°C and 37°C and different nutrient concentrations were 0.1%, 1% and 10% Tryptic Soy Broth (TSB). After obtaining samples after 1, 2, 3 and 4 days respectively, the biofilm surfaces were visualised using atomic force microscopy (AFM) and epifluorescence microscopy. Less cell attachment was displayed at lower temperatures and nutrient limitations. The roughness profile of the early stages of biofilm development was explored by the novel application of various existing statistical methods. Benoit software was applied for the statistical analysis of various data sets obtained from AFM imaging, using power spectrum, variogram and wavelet methods to determine the Hurst exponent. The variogram method proved to be the most suitable to describe biofilm surface profiles with consistent values of ± 0.9, indicating that biofilm growth behaviour will continue in a similar pattern. Fractal dimension values of images obtained from epifluorescence microscopy was determined by the box dimension method. The values described the self-affine patterns displayed by biofilms. Using the results of these investigations, a series of models concerning the initial stages of biofilm formation was compared to describe the development of colony patterns. This study showed that the AFM and epifluorescence microscopy can be used as analytical tools for raw data assembly. It also demonstrated a novel application of existing statistical methods in order to describe the early stages of biofilm formation. Using this approach it was shown that the early stages of biofilm formation display certain colony patterns that can be described and predicted. Such information may be used in efforts to control biofilm formation.
AFRIKAANSE OPSOMMING: Komplekse biofilmgemeenskappe is reeds breedvoerig m die verlede bestudeer. Minder werk is op vroeë stadiums van biofilmvorming gedoen. Hierdie studie het gepoog om die aanvanklike koloniseringspatrone van biofilmvorming op verskillende substrate en onder verskillende omgewingstoestande kwantitatief te bepaal met nuwe metodes om die oppervlakprofiele van biofilms te beskryf. Biofilms is gekweek op glas, polivinielchloried (PVC) en gepoleerde vlekvrye staal. Resultate van mikroskopie, gevolg deur wiskundige analise en kontakhoek-metings het getoon dat glas die mees geskikte substraat vir hierdie studie is. Die produksie van meer ektrasellulêre polimeriese substanse (EPS) en oënskynlik minder selaanhegting is waargeneem op PVC en gepoleerde vlekvrye staaloppervlaktes. Twee verskillende reekse eksperimente IS uitgevoer waar biofilms op glas gekweek IS. Biofilm-morfologie is geanaliseer onder verskillende toestande van temperatuur en nutriënt-konsentrasie. Verskillende temperatuur-toestande was goC, 22°C en 37°C en verskillende nutriënt-konsentrasies was 0.1%, 1% en 10% Tryptic Soy Broth (TSB). Nadat monsters onderskeidelik na 1, 2, 3 en 4 dae verkry is, is die biofilm oppervlaktes gevisualiseer deur atoomkrag mikroskopie (AFM) en epi-fluoressensie mikroskopie. Minder selaanhegting is waargeneem by laer temperature en nutriënt-beperkinge. Die grofheidsprofiele van die vroeë stadium van biofilm-ontwikkeling is ondersoek deur die nuwe toepassing van verskeie bestaande statistiese metodes. Benoit-sagteware is gebruik om die statistiese analise van verskeie data-stelle van AFM beelde te ondersoek deur power spectrum, variogram en wave/et -metodes te gebruik om die Hurst-eksponent te bepaal. Die variogram metode het voorgekom as die mees geskikte om biofilm oppervlakprofiele te beskryf met konstante waardes van ± 0.9, wat aandui dat biofilm groei sal aanhou in 'n soortgelyke patroon. Fraktale dimensie-waardes van beelde wat met epi-fluoressensie mikroskopie verkry is bepaal deur toepassing van Benoit-sagteware se box dimension metode. Die waardes beskryf die selfherhalende patrone wat deur biofilms gedemonstreer word. Deur die resultate van hierdie ondersoeke te gebruik, is 'n reeks modelle aangaande die aanvanklike stadiums van biofilmvorming vergelyk om die ontwikkeling van koloniepatrone te beskryf. Hierdie studie het getoon dat die AFM en epi-fluoressensie mikroskopie gebruik kan word as analitiese gereedskap vir rou data-versameling. 'n Nuwe toepassing van bestaande statistiese metodes om die vroeë stadiums van biofilmvorming te beskryf, is ook gedemonstreer. Deur hierdie benadering te gebruik, is getoon dat die vroeë stadiums van biofilmvorming sekere koloniepatrone aandui wat beskryf en voorspel kan word. Sulke inligting kan gebruik word in pogings om biofilmvorming te beheer.
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Pepin, Ronald (Ronald Raymond) 1961. "Application of critical chain to staged software development." Thesis, Massachusetts Institute of Technology, 1999. http://hdl.handle.net/1721.1/9750.
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Thesis (S.M.)--Massachusetts Institute of Technology, System Design and Management Program, 1999.Includes bibliographical references (leaves 58-59).
One in three IT projects are canceled before they are completed. Of the projects that are completed, over 75% are late, over budget or are released with reduced functionality. Average cost overruns are 189%; average schedule overruns are 222% (The Standish Group). The software development process and the project management techniques are critical components in completing a development project on time and on budget. Critical Chain Project Management techniques and a Staged Development process were designed to address issues that contribute to the large number of schedule and cost overruns. Critical Chain is based on Theory of Constraint principles developed by Eliyahu Go ldratt. Critical Chain offers practical methods for planning, scheduling, tracking and mitigating schedule risk in a development program. Staged Development, a form of an incremental product development lifecycle, is considered to be a software development best practice. Staged Development promises faster development schedules, increase progress visibility and higher quality. In this study the author researches, applies and analyzes the Critical Chain and Staged Development methodologies. The combination of the two methodologies created a process that served to increase likelihood of project success.
by Ronald Pepin.
S.M.
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Steinfelt, Victoria. "Ages and Stages: 4 to 8 Year Olds." College of Agriculture and Life Sciences, University of Arizona (Tucson, AZ), 1998. http://hdl.handle.net/10150/156943.
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3 pp.To understand children, their development, needs and uniqueness is vital for parents. This publication uses tables to outline the mental, social and physical development for each group of children from 4 to 8 year old.
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Sanders, Karen Nordberg. "The Role of a Developmental Screening in Kindergarten - First Grade Placement." Thesis, North Texas State University, 1986. https://digital.library.unt.edu/ark:/67531/metadc331090/.
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The purposes of this study were to determine if a kindergartener's developmental stage correlates with subsequent scholastic achievement, to determine whether developmentally younger children who repeat kindergarten attain higher academic achievement than developmental 1y younger children who do not repeat kindergarten, and to investigate the relationship between head circumference, developmental age, and achievement. Ninety-seven kindergartners of various ethnicity and socio-economic status were administered the Gesell School Readiness Screening Test to determine developmental age and were followed academically for three years. Head circumference was noted periodically to measure brain growth. The hypotheses predicted significant positive correlations between developmental age in kindergarten and scores on later achievement tests. Further, it was predicted that children below 5.3 years in developmental age who delayed entrance to first grade would score significantly higher on first grade achievement tests than match-paired promoted students. It was hypothesized that there would be significant correlations between head circumference growth and (a) gains in achievement test scores and (b) developmental age at kindergarten. The first hypothesis, tested by Pearson Product Moment Correlations, established the existence of significant correlations between developmental ages of test subjects and their scores on four academic achievement tests. The results indicated that developmental age was a better predictor of achievement test scores than chronological age. Since only five children in this study were retained in kindergarten, hypothesis 2 was analyzed descriptively. Mean scores on first grade achievement tests were higher for the retainees than for the "at risk" non-retainees. Hypothesis 3 was tested by stepwise multiple regression. At the first step, the linear trend between the independent variable, CTBS score, and the dependent variable, I TBS score, was calculated and found to be significant at the .001 level. The addition of head circumference growth to the equation did not add significantly to the prediction of I TBS scores from CTBS scores. There was a significant negative correlation between developmental age in kindergarten and head growth.
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Cambron, Liz Doralyn. "Factors Affecting Metabolism During Non-Feeding Stages in Insects." Diss., North Dakota State University, 2020. https://hdl.handle.net/10365/31868.
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Although feeding is important for optimal development and growth in insects, there are several points during the insect life cycle that are non-feeding: metamorphosis, pupation, and overwintering. Non-feeding periods also occur in response to internal cues, such as feedback from nutrient thresholds and immune responses being activated. Additionally, as an insect goes through different developmental stages, its nutritional requirements change in response to or in preparation for non-feeding periods. Most physiological responses like feeding are regulated through an interconnection of pathways, but how these networks change in response to different energy demands, such as immune challenges or changes in metabolism, is poorly understood. One significant pathway that is involved in regulating several physiological processes is the insulin signaling pathway. In my dissertation research, I tested hypotheses explaining the regulation of physiological processes during non-feeding periods in two agriculturally relevant insects, Manduca sexta and Megachile rotundata. First, I investigated how internal cues such as dietary lipid content and immune challenges cause non-feeding periods in M. sexta. Then, I investigated how insulin signaling regulates development during a non-feeding period like overwintering changes in M. rotundata. Since the insulin signaling (IIS) pathway is critical for development and growth, I focused on testing if this pathway plays a role in regulating non-feeding periods. My research showed that increased dietary lipid content causes a cessation of feeding, which suggests there is a possible lipid threshold that when reached, causes M. sexta to switch from lipid consumption for storage to lipid excretion. When looking at another cue like immune challenges, my results showed that during a bacterial infection, a Toll-mediated suppression of IIS pathway may be regulating feeding and causing a non-feeding period exhibited as sickness-induced anorexia. Lastly, my results also showed that the IIS pathway is suppressed in overwintering M. rotundata, and that this process can change in response to temperature. Overall, my dissertation research showed that the insulin signaling pathway and nutrient content play a vital role in regulating non-feeding periods. Investigating insulin signaling, lipid metabolism, and innate immunity in these species closes a gap in knowledge of invertebrate development.
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Hansson, Sanna, and Sonja Lundeberg. "Skolgårdens plats i den föränderliga staden." Thesis, Malmö universitet, Institutionen för Urbana Studier (US), 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-45248.
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I stadens förändringsprocess, ständigt präglad av nya ideal, ska många intressen förenas och beaktas vid utformningen av skolgårdar. Med utgångspunkt i naturens betydelse för barns hälsa och utveckling undersöker denna studie två skolgårdar i Malmö utifrån tre perspektiv: skolgårdarnas utformning, högstadieelevers användning av och preferenser på skolgården samt planerarens prioriteringar och tillvägagångssätt vid utformningen av skolgårdsmiljöer. Syftet är, genom förståelse för hur dessa tre perspektiv kan förenas, öka kunskapen kring hur skolgårdarna kan planeras mer socialt och ekologiskt hållbart i den föränderliga staden. Detta undersöks med en mixad metod genom platsobservationer, enkätundersökningar och intervjuer. Empirin påvisar en relativt passiv inställning till skolgården bland eleverna, oberoende av skolgårdens storlek och mängd grönska samt att de överlag prioriterar social interaktion och mobilanvändande på rasterna. Tolkningen av det empiriska materialet utifrån teorin tyder på att det är grönskans kvalitet som påverkar elevernas intresse för att ta del av miljön. Genom intervjuerna framkom det att utformningen av ett grönt ramverk som erbjuder olika rumsligheter kan bidra till en mer jämlik, inkluderande och hållbar skolgårdsmiljö. Den ideala skolgårdsmiljön, som kan anses vara en där naturen företräds, speglar dock inte nödvändigtvis elevernas uppfattning av den ideala skolgården. Elevernas preferenser kan däremot få ta plats inom det hållbara ramverket, genom aktiv gestaltning.Within the city's transformative process, constantly tinged by new ideals, different interests must be united and considered in the planning and design of school grounds. Based on the importance of nature for children's health and development, this study examines two school grounds in Malmö from three perspectives: the school grounds design and shape, the use and preferences of the students on the school grounds, and the planner´s priorities and proceedings in planning school ground environments. The purpose is, through an understanding of how these three perspectives can unite, to increase knowledge on how school grounds can be planned more socially and ecologically sustainable in the transformative city. This is investigated with a mixed method through site observations, surveys and interviews. The empirical evidence shows a relatively passive relation to the school ground among the students, regardless of the school grounds size and amount of greenery, and generally they prioritize social interaction and mobile phone use during breaks. The interpretation of the empirical material, based on the theory, indicates that it is the quality of the greenery that affects the student’s interest in using the environment. Through the interviews, it emerged that the design of a green framework that offers different spatialities can contribute to a more equal, inclusive and sustainable school ground. The ideal environment of the school ground, which can be considered one that is characterized by natural environments, does not necessarily reflect the student's ideal of it. The students' preferences can however be accommodated within the sustainable framework through continuous design.
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Sundström, Peter. "Orter i stadens närhet." Doctoral thesis, Örebro universitet, Institutionen för humaniora, utbildnings- och samhällsvetenskap, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-27677.
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This thesis examines localities in the vicinity of cities, starting with Ekeby- Almby which is situated near Örebro. In the past twenty years, Ekeby- Almby has experienced vast sociodemographic changes. These lines of development give rise to a number of questions. For example, does the socioeconomic change of Ekeby-Almby reflect a general trend for this kind of locality? What are the perspectives and concepts that characterise the planning of these localities, and what is the significance of these suburban areas for the urban development as a whole? The purpose of this thesis is to examine the peri-urban localities, their role in, and their significance to, the development of cities. The thesis is made up of three empirical parts. Some of the main results are that the peri-urban localities can bedescribed as continuously growing, even during periods of shrinking towns and growing countryside (70s and 80s), and re-urbanisation (90s and 00s). Other results from the study are that layers of peri-urban localities with partially separatesocioeconomic profiles become apparent. Together these localities are, in various ways, part of the city’s socioeconomic differentiation. Finally, the result from the study indicates that the development of localities is shaped by a series of structures, and actors operating in relation to these. The development of the peri-urban localities can, theoretically, be seen as an urban counter- urbanisation, but perhaps primarily as a Swedish periurbia, and thus as an extension of the city, often described as an urban sprawl. This study also discusses the role of the peri-urban locality in the city’s social geography, where it among other things can be described as the ”hidden” space of the segregated city. Another aspect of the peri-urban locality is that it can be seen as a place which is important in an intermunicipal competition in population growth.
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Penn, Bennett H. "Promoter-specific restriction of MyoD binding and feed-forward regulation cooperate to produce a multi-staged transcriptional program during skeletal myogenesis /." Thesis, Connect to this title online; UW restricted, 2004. http://hdl.handle.net/1773/4993.
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Kolbaeva, K. (Kunduz). "Students’ motivation in group development stages during collaborative learning." Master's thesis, University of Oulu, 2017. http://urn.fi/URN:NBN:fi:oulu-201706022393.
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When students work in small groups, it is expected that they experience five stages of group development to perform well; forming, storming, norming, performing and adjourning. Yet, the duration of each stage namely, when particular stage starts and when it finishes was not investigated in the previous researches. Furthermore, all the stages have features that characterize them, most of the features describe emotional state of students, whereas motivational level of students is still not clear. So, taking into account of the previous research gaps, the aim of this thesis is to examine duration of group development stages, and how to characterize students’ motivation at the different stages of collaborative learning. The research involved 15 first-year teacher education students. Four small-groups (3–4 members in each) were engaged in collaborative learning tasks on math within six sessions. Except the tasks, they were assigned to discuss macro-level scripts: Orientation questions in the beginning, Checkup questions in the middle, and Reflection questions at the end of the each session. The data was collected by videotaping of students’ small-group work. For the data analysis of this thesis, the scripted phases were transcribed and coded based on the thematic categories.
The results show that almost all of the group developmental stages may last one or two collaborative sessions. There are quite a lot of overlaps between the stages, when they are mixed in one session. Another point is that, not all five stages may be present in the group development. As this study shows, adjourning stage was not included in the analysis since none of the groups did experience it.
According to the analysis, the groups’ motivational state vary from one stage to another. At the beginning of the course students are more motivated and at the end of the course students’ motivation is low. The thesis demonstrates which stage is specifically more beneficial for students’ high motivation. It can be concluded that the knowledge of groups’ development stages are useful for the teachers in designing the collaborative learning sessions. Taking into account the emotions and motivation that students are expected to have at the different stages, the teachers may enhance learning process.
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Meyer, Joseph. "Early Stages of Game Development Company for Physics Education." Case Western Reserve University School of Graduate Studies / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=case1496423532596752.
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Berdeja, Aramayo Mariam. "Effects of water stress and rootstock genotype on grape berry composition." Thesis, Bordeaux 2, 2013. http://www.theses.fr/2013BOR22103/document.
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Au cours des prochaines années, il est prédit que le changement climatique va influencer la production des cultures et impacter négativement le secteur agricole. Parmi les cultures mondiales majeures, la vigne est cultivée pour ses baies, qui sont la base de produits à forte valeur ajoutée (vin, liqueurs, et métabolites secondaires utilisés dans les industries pharmaceutiques et cosmétologiques) et dont le métabolisme est fortement sensible au climat. Cependant, la réponse au niveau de la composition de la baie ainsi que les mécanismes moléculaires sous-jacents mettant en évidence la capacité de l’interaction porte-greffe/greffon à influencer le métabolisme de la baie dans des conditions de stress hydrique est encore très peu étudiée et compris. Dans ce contexte, cette thèse a eu pour objectifs de répondre à ces questionnements en combinant des approches ecophysiologique, biochimique et transcriptomique. Vitis vinifera cv. Pinot noir greffé soit sur le porte greffe 110R (tolérance à la sécheresse, vigueur conférée moyenne à forte) ou 125AA (sensible à la sécheresse, forte vigueur conférée) ont été étudié au cours de 3 années (2009, 2010 et 2011), au vignoble et dans des conditions témoin (pluviométrie normale) ou de stress hydrique provoqué. Différents paramètres physiologiques (statut hydrique et rendement) ainsi que le profil métabolique de la baie (sucres, acides organiques, acides aminés et anthocyanes) ont été caractérisés à quatre stades de développement (E-L 33, E-L 35, E-L 36, E-L 38). D’autre part, une analyse microarray sur génome complet a également été réalisée pour deux années (2009 et 2010) et deux stades de développement critiques et représentatifs (E-L 35 et E-L 36). Dans son ensemble, cette thèse fournit des nouveaux éléments concernant la réponse métabolique de la baie au porte-greffe et à la contrainte hydrique, et met en évidence des possibles mécanismes moléculaires impliqués dans cette réponseClimate change is expected to influence crop production and to impact negatively the agricultural sector in the future. Among the major crops cultivated worldwide, grapevine provides berries that are the basis of high added value products (wines, liquors, and secondary metabolites used in the pharmaceutical and cosmetological industry) and whose metabolism is strongly sensitive to climate (vintage effect). However, the response of berry composition and the molecular mechanisms underlying the ability of rootstock/scion interaction to influence grape berry metabolism under drought stress are still poorly understood. In this context, this work aimed to fill the gaps on the aforementioned questions by combining comprehensive ecophysiological measurements, detailed metabolite analysis, and whole-genome transcriptome analysis. Vitis vinifera cv. Pinot noir grafted on either rootstock 110R (drought tolerant, mid- to high vigor) or 125AA (drought sensitive, high vigor) were studied during three growing seasons (2009, 2010, and 2011) in the field under normal rainfall or water shortage conditions. We characterized different physiological parameters (water status and yield components) and berry metabolomic profiles (sugars, organic acids, free amino acids and anthocyanins) during four developmental stages (E-L 33, E-L 35, E-L 36, E-L 38). Besides we also performed a microarray analysis in two years (2009 and 2010) at two critical and representative developmental stages (E-L 35 and E-L 36). Overall, this work provides novel insights into the response of grape berry metabolites to rootstock and to drought and uncovers some possible molecular mechanisms underlying the berry response to different rootstock/water status combinations
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Delves, C. J. "Developmental processes in filarial worms." Thesis, University of Liverpool, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.377098.
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Lindström, Jonas. "Drömmen om den nya staden : Stadsförnyelse i det postsovjetiska Riga." Doctoral thesis, Stockholms universitet, Sociologiska institutionen, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-75785.
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The aim of this thesis is to shed light on Post-Soviet urban renewal and people’s perceptions of changes that recently occurred in both the city of Riga and Latvian society more generally since the dissolution of the Soviet Union in the early 1990s. More specifically, this study examines how these perceptions are manifest in Riga’s ongoing renewal. Through applying aspects of continuity and discontinuity, I illustrate how the urban renewal of Post-Soviet Riga uncovers imaginary and emotional aspects of the city and how these are interpreted in relation to the past, present and the future. This study introduces the concept “urban postperestroika” and one important difference between this concept and the more common concepts post-socialist, post-communist or post-Soviet is that the former highlights a process while the latter ones largely highlight the state. The starting point is how urban phantasmagorias – contemporary dreams of the future of the city – elucidate urban renewal processes in general and urban postperestroika in particular. In Riga’s ongoing renewal processes I identify three main trajectories in relation to aspects of the past, present and the future: de-Sovietization, globalization and Lettification. Together, these three trajectories constitute an engine that produces urban phantasmagorias. The dissolution of the Soviet Union has given rise to notions that everything is “back to normal” again, and these notions of normalcy have influenced urban renewal processes. The dilemmas, as shown in this thesis, concern the Soviet period and its remaining psychical structure which give the impression of being too conspicuous to eliminate and too contradictory to assimilate. The study illustrates the difficulties of building new urban and societal structures on the remains of pre-existing orders. Such difficulties of course lead to contradictory and ambiguous world views and to new dysfunctional situations that have to be managed in the future.
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Viscarra, Hansson Braulio Johan, and Sosa Fania Verona Perez. "Förortstorgens roll för en hållbar stadsutveckling i den postindustriella staden – Hermodsdalstorget, Malmö." Thesis, Malmö högskola, Fakulteten för teknik och samhälle (TS), 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-22589.
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Denna uppsats fokuserar på förortstorgens potentiella bidrag till en hållbar stadsutveckling i den postindustriella staden. I uppsatsen problematiseras ett särskilt torg, Hermodsdalstorget i stadsdelen Fosie i sydöstra Malmö.I Malmö Stads senaste översiktsplan betonas att den sociala utvecklingen av Malmö, inte varit positiv på senare år och att en viktig utmaning ligger i att integrera de marginaliserade områden med innerstaden.Av dessa anledningar satsas det bland annat på länkande gång- och cykelstråk som binder samman stadsdelar och utgörs av väldefinierade gaturum och attraktiva mötesplatser. Hermodsdalstorget väntas utgöra en sådan mötesplats i ett framtida Fosiestråksom kommer att länka Malmös sydöstra förorter med innerstaden.Torget är idag en bortglömd plats som varken erbjuder egenskaper för att upplevas som attraktivt eller innehar förutsättningar för social interaktion och integration. Tillståndet är så dåligt att torget, i en tidningsartikel från 2002, till och med kommit att kallas för ”Malmös tristaste torg”. På grund av torgets dåliga skick har det funnits mer än tio år gamla omvandlingsplaner för utvecklingen av platsen. Trots detta har en omvandling uteblivit, framförallt på grund av bristen på samverkan och en delad vision mellan privata fastighetsägare kring torget och kommunen.Avslutningsvis, i denna uppsats, presenteras ett praktiskt genomförbart projektförslag, som fokuserar på ett första steg, i ett större omvandlingsprojekt av Hermodsdalstorget, och som har som syfte att göra ett nytt försök till samverkan och dialog mellan de aktörer som i dagsläget har mandat över torget.Förhoppningen är att projektförslaget banar väg för en omvandling av detta torg och att torget i framtiden fungerar som en attraktiv mötesplats längst med Fosiestråket; i ett mindre segregerat Malmö.This thesis focuses on the potential of suburban squares to contribute to sustainable urban development in post-industrial cities. In the thesis a particular square is in focus: Hermodsdal’s square in the Fosie-district in southeastern Malmoe(Malmö).In the last general development plan for Malmoe it is emphasized that the social development of Malmoe has not been positive in recent years, and that an important challenge lies in integrating the marginalized suburban areas with the inner city. One solution, for integrating the city, is the creation of linking pedestrian and bicycle paths that connect neighborhoods; paths that consist of well-defined street-areas and attractive meeting places. Hermodsdal’s Square is expected to form such a meeting place in a future Fosie Path, which will link Malmoe’s southeastern suburbs with the inner city. Hermodsdal’s square is today a forgotten place that does not offer features to be perceived as attractive nor meets the conditions needed for social interaction and integration. The actual condition of the square is so bad that Hermodsdal’s Square has, in a newspaper article from 2002, even been called ”Malmoe’s dullest Square”. Because of the square’s poor condition, there have been more than ten years old conversion plans for the development of the site. Despite this, the conversion has not become reality, mainly because of lack of synergy and a shared vision between private property owners around the square and the municipality. Finally, a central purpose of this thesis is presenting a practical project proposal, which focus on the first step in a major transformation project of Hermodsdal’s Square; a project which aims to make another attempt to collaboration and dialogue between the private actors around the square and the municipality. The expectation is that the project proposal paves the way for a transformation of this square; a square which in the future will act as an attractive meeting lace along the Fosie Path, in a less segregated Malmoe.
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Sabala, Izabela. "Regulation of somatic embryo development in Norway spruce (Picea abies) : a molecular approach to the characterization of specific developmental stages /." Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 1998. http://epsilon.slu.se/avh/1998/91-576-5603-7.gif.
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King, Gabriella Louise. "Palestinian nationalism from 1917 to 1989 : four stages of development." Thesis, University of British Columbia, 1989. http://hdl.handle.net/2429/28250.
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This thesis examines the development of Palestinian nationalism in the twentieth century by dividing it into four periods. In each of these four periods anti-colonial nationalism and Arab nationalism are applied to the Palestinian case. Special attention is paid to the Palestinian vision of Zionism, the role of the Arab states in Palestinian politics, the vision of a future Palestinian state and how it was to be achieved.
In the early twentieth century, Palestinian national feelings were stirred as opposition was organized against Zionist immigration and British rule. Both the Zionists and the British were considered to be motivated by colonial aims in the stirring phase. The second period in the development of Palestinian nationalism, which was clearly a pan-Arab period, took shape soon after the establishment of the state of Israel in 1948 at which time the success of pan-Arabism was believed to be the best way to achieve an independent Palestinian state.
The third phase in the evolution of Palestinian nationalism, which is dealt with in chapter two, is marked by the defeat of the Arab states in the June war of 1967, at which time pan-Arabism lost much of its appeal. This defeat marked the rise of a new Palestine Liberation Organization and although there were a variety of groups and ideologies within the organization, it is possible to make some generalizations about Palestinian nationalism in this period. The PLO attempted to reduce the role of the Arab states in Palestinian affairs, they expressed Marxist ideas and a militant line, and the organization continued to see Israel as a colonial settlement that was to be eliminated.
Finally, this thesis characterises the fourth period in the evolution of Palestinian nationalism as a gradual process of change that occurred throughout the 1970s and 1980s. It involved an eventual acceptance of Israel and a partition of Palestine, thus rejecting the anti-colonial ideas that had been at the centre of the movement since the stirring phase. This thesis concludes by suggesting that these changes are likely to make it difficult for the PLO to maintain its fragile unity.Arts, Faculty of
Political Science, Department of
Graduate
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Spielman, Jade B. "The effects of parental loss throughout adolescent stages of development." Manhattan, Kan. : Kansas State University, 2007. http://hdl.handle.net/2097/467.
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Levy, Zeeva. "Estimating the effort in the early stages of software development." Thesis, London School of Economics and Political Science (University of London), 1990. http://etheses.lse.ac.uk/2088/.
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Estimates of the costs involved in the development of a software product and the likely risk are two of the main components associated with the evaluation of software projects and their approval for development. They are essential before the development starts, since the investment early in software development determines the overall cost of the system. When making these estimates, however, the unknown obscures the known and high uncertainty is embedded in the process. This is the essence of the estimator's dilemma and the concerns of this thesis. This thesis offers an Effort Estimation Model (EEM), a support system to assist the process of project evaluation early in the development, when the project is about to start. The estimates are based on preliminary data and on the judgement of the estimators. They are developed for the early stages of software building in which the requirements are defined and the gross design of the software product is specified. From these estimates only coarse estimates of the total development effort are feasible. These coarse estimates are updated when uncertainty is reduced. The basic element common to all frameworks for software building is the activity. Thus the EEM uses a knowledge-base which includes decomposition of the software development process into the activity level. Components which contribute to the effort associated with the activities implemented early in the development process are identified. They are the size metrics used by the EEM. The data incorporated in the knowledge-base for each activity, and the rules for the assessment of the complexity and risk perceived in the development, allow the estimation process to take place. They form the infrastructure for a 'process model' for effort estimating. The process of estimating the effort and of developing the software are linked. Assumptions taken throughout the process are recorded and assist in understanding deviations between estimates and actual effort and enable the incorporation of a feedback mechanism into the process of software development. These estimates support the decision process associated with the overall management of software development, they facilitate management involvement and are thus considered as critical success factors for the management of software projects.
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Kuzema, P. O., M. Ya Dovzhyk, and O. S. Kuzema. "Main Stages of Development and Recent Advances of Mass Spectrometry." Thesis, Sumy State University, 2015. http://essuir.sumdu.edu.ua/handle/123456789/42625.
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It has been presented the review and analysis of the main evolution stages of one of the most efficient methods for investigation of composition and properties of substances – mass spectrometry. The advantages and application area of the method were described, as well as physical and technical peculiarities of the devices for its realization were considered.
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Yogasara, Thedy. "Anticipated user experience in the early stages of product development." Thesis, Queensland University of Technology, 2014. https://eprints.qut.edu.au/66240/2/Thedy_Yogasara_Thesis.pdf.
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This research investigates users' anticipation of their future experiences with interactive products to support design for experience in the early stages of product development. This research generates new knowledge of anticipated user experience (AUX), which reveals users' tendency to perceive the pragmatic quality of products as the main determinant of their positive future experiences. The AUX Framework has been an important outcome of this study. The exploration of the components of this framework allows a better prediction and understanding of users' underlying needs and potential usage contexts valuable for the early design phases.
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Chance, Charles Allen. "Dependence of craniofacial growth on stages of cervical vertebral maturation and stages of mandibular canine mineralization." View the abstract Download the full-text PDF version, 2006. http://etd.utmem.edu/ABSTRACTS/2006-005-chance-index.htm.
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Thesis (M.S.)--University of Tennessee Health Science Center, 2006.Title from title page screen (viewed on October 8, 2007 ). Research advisor: Edward Harris, Ph.D. Document formatted into pages (xiii, 156 p. : ill.) Vita. Abstract. Includes bibliographical references (p. 137-147).
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Gordon, Joel Christopher. "Development of the Full Height Truss Frame." Thesis, Georgia Institute of Technology, 2005. http://hdl.handle.net/1853/7136.
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The full height truss frame (FHTF) is an exciting new residential framing system in response to the need for low floor-to-floor steel construction. The FHTF has the potential to provide low floor-to-floor heights, a column free first floor area, an integrated frame that uses the entire height to resist loads, and the capacity to resist both gravity and lateral loads.
Because of its configuration, the full structural height can be used to resist loads. A FHTF is made up of stacked floor trusses that result in one full height truss spanning the entire width of the building. The FHTF is constructed in a conventional manner one floor at a time. The strength, inertia, and truss height will increase as each floor is added. Therefore, the construction sequence will affect the final stresses in the members.
The purpose of this thesis was to analyze and design two prototype FHTFs, to compare the economy of the prototypes with similar staggered truss frames, and to develop an approximate method to calculate staged member stresses. Each prototype was analyzed using a computer program and designed according to the 2001 American Institute of Steel Construction Load and Resistance Factor Design. The prototypes were used to assess the strength and serviceability of the structures, and the results of the staged analysis were used to validate the numerical method developed to approximate a staged loading sequence based on the non-staged dead load results.
The results of the analysis and design of the prototypes was the initial step in confirming the viability of the FHTF for use in the residential multistory market. FHTFs can be designed with preexisting procedure, and are capable of offering low floor-to-floor heights. The prototypes exhibited excellent lateral stiffness against wind loads. The numerical method for estimating the staged dead load accurately approximated the results of the analysis preformed by ETABS. The numerical method can be used to simulate a variety of sequences in order to optimize the stages. Lastly, the FHTF was shown to be competitive with the staggered truss systems in terms of material usage, fabrication, and construction.
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Mahajan, Gautam. "MECHANOBIOLOGY OF BRAIN-DERIVED CELLS DURING DEVELOPMENTAL STAGES." Cleveland State University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=csu1578332547849308.
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Parent, Justin. "Multidimenional Assessment Of Parenting Across Three Developmental Stages." ScholarWorks @ UVM, 2017. http://scholarworks.uvm.edu/graddis/613.
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BACKGROUND: The primary aim of the current study was to create a new measure of parenting practices, constituted by items from already established measures in order to advance the measurement of parenting practices in clinical and research settings. The current study utilized five stages designed to select only the best parenting items, establish a factor structure consisting of positive and negative dimensions of parenting, meaningfully consider child developmental stage, ensure strong psychometric properties, and provide initial evidence for the validity of the final measure.
METHODS: A total of 1,790 parents (44% fathers) were recruited online through Amazon's Mechanical Turk for three cohorts: Stages 1 (N = 611), 2 (N = 615), and 3 (N = 564). Each sample was equally divided by child developmental stage: Young childhood (3 to 7 years old), middle childhood (8 to 12 years old), and adolescence (13 to 17 years old). Parenting items were selected and adapted from several well-established parenting scales. Measure development followed five rigorous stages using separate samples for each set of factor analyses as advocated by methodologists. Advanced statistical methods were employed for determining final factor structure (e.g., exploratory structural equation modeling - ESEM) and reliability (omega coefficient; longitudinal ESEM), as well as providing initial support for validity (e.g., latent curve modeling - LCM).
RESULTS: Through a five-stage empirical approach, the Multidimensional Assessment of Parenting Scale (MAPS) was developed, successfully achieving all aims. The MAPS factor structure included both positive and negative dimensions of warmth/hostility and behavioral control that were appropriate for parents of children across the developmental span. Seven out of eight MAPS subscales demonstrated excellent reliability (above .80). LCM analyses provided initial support for the validity of all MAPS subscales.
DISCUSSION: Although the stages of the current study embody an empirical approach to scale development, it also has important theoretical aspects. The factor structure of the MAPS updates prior the theoretical conceptualization of parenting practices (Schaefer, 1959) in order to inform new research and applications. Future directions are discussed.
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Turner, Kara Jane. "Telomere length and distribution in three developmental stages." Thesis, University of Kent, 2015. https://kar.kent.ac.uk/47463/.
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Telomeres are specialised nucleoprotein structures present at the ends of each chromatid that function to maintain genome stability. It is well established that a gradual decline in telomere length is associated with the process of cellular ageing, and thereby to the pathobiology of age-related diseases. In addition, the localisation of the telomere at the nuclear periphery plays an important role in the spatio-temporal organisation of the genome and in ensuring faithful segregation of chromosomes during meiosis. The aims of this thesis were to investigate telomere localisation in the nucleus, and telomere length in three hitherto early stages of development, gametogenesis, preimplantation embryogenesis and the neonatal period. Specifically: 1. To test the hypothesis that telomeres localised at the nuclear periphery in sperm cells and that this organisation was altered in sub-fertile men 2. To optimise a means of assessing average telomere length using DNA from small sample sizes and using whole genome amplified DNA from single cells 3. To investigate the role of telomere length in reproductive ageing and aneuploidy generation in women by testing the hypothesis that telomere length is significantly shorter in the first polar bodies and cleavage stage embryos of older women 4. To test the hypothesis that “preterm at term” babies (i.e. premature babies assessed at the time of their due date) displayed genetic signs of premature ageing (as manifested by significantly shorter telomeres than their term born counterparts) alongside the already established clinical signs (characterised by hypertension, diabetes and altered body fat distribution) Results confirmed the peripheral distribution of telomeres in the sperm heads of normally fertile males (using both 2D and 3D imaging) plus the novel finding that telomere distribution patterns are altered in the sperm heads of infertile males. Secondly, a reliable means of measuring telomere length was optimised in order to assess average telomere length using DNA from small sample volumes (down to single cells). Using this technology, average telomere length analysis in polar bodies and embryos found no evidence to support the hypothesis that telomere length is associated with either advanced maternal age or aneuploidy generation. Similarly, results suggest that telomere length is not significantly shorter in “preterm at term” infants compared to term born controls, thus providing no evidence that telomere attrition is involved in the pathobiology of the ‘aged phenotype’ observed in preterm infants. Taken together, results from this thesis provide some novel insights into the function of these highly important features of the genome, but also highlight that a great deal remains to be uncovered in the complex molecular mechanisms that contribute to the regulation of telomere length and nuclear distribution.
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Hyde, Marissa Cathryn. "Personage and Post-Adolescence in F. Scott Fitzgerald's This Side of Paradise." Cleveland State University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=csu1611535243379139.
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Damberg, Johanna, and Josefin Lund. "Grönstrukturens plats i staden : En studie om Karlstads centrum ekologiska infrastruktur." Thesis, Karlstads universitet, Institutionen för geografi, medier och kommunikation (from 2013), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kau:diva-74202.
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Det är allmänt känt att det sker en kontinuerlig ökning av världens befolkning och följden av detta är att städer växer kraftigt. Det medför en förtätning i stadskärnan och som en konsekvens sker en konflikt mellan grönstrukturen och nybyggnationer. Varje kommun strävar efter tillväxt och balansen för hållbar tillväxt är subtil och det är här intresset för uppsatsen grundar sig. Uppsatsens syfte är att undersöka hur stor plats grönstrukturen får i planeringen av Karlstads stadskärna. För att besvara syftet studeras förtätningens olika utmaningar, samt hur ekocentrism och antropocentrismens etiska synsätt uttrycks i planeringen. Synsätten skapar en förståelse för hur och för vem stadsrummet planeras för. Det finns en skildring i planeringen där antropocentrismen under en längre tid kritiseras av ekocentrismen. Det har genomförts en kvalitativ metod för att besvara syftet och frågeställningarna. En dokumentanalys har utförts, samt en gruppintervju med representanter från Karlstads kommun. Resultatet om grönstrukturen i centrum visar sig ha många likheter mellan de olika metoderna, vilket ökar uppsatsens trovärdighet. I samband med att staden förtätas minskar gaturummet och det leder till att det skapas en konflikt mellan olika aktörers intressen för platsens användning. Aktörer har ett stort intresse av en hög ekonomisk tillväxt och det innebär att grönskan värderas lägre i planeringen mot en hållbar stadsutveckling till skillnad från bostäder, verksamheter och parkeringsplatser. Grönstrukturen saknar riktlinjer i planeringen, vilket gör att grönskan är svår att motivera när samhällsplaneringen styrs av en antropocentrisk syn. Sammanfattningsvis skapar det svårigheter när grönstrukturens plats ska motiveras i Karlstads växande stad.It´s commonly known that there is a continuous increase of the world´s population and the consequence of this is that cities are growing rapidly. This means a densification in the center of the city and a consequence of this is a conflict between the green structure and the new construction. Each city seeks for growth and the balance for sustainable development is subtle and this is where the essay found its interest. The purpose of the essay is to look over how big influence the green structure gets in the planning of Karlstads city. In order to answer the purpose, the various challenges of the densification are studied, as well as how ecocentrism and anthropocentrism ethical approach is expressed in the planning. The approach creates an understanding of how and for whom the urban space is planned. There is a depiction in the planning where anthropocentrism has long been criticized by ecocentrism. A qualitative method has been implemented to answer the purpose and the questions. A document analysis has been performed, as well as a group interview with representatives from Karlstads kommun. The result of the green structure in the city proves to have many similarities between the different methods, which increases the credibility of the essay. In connection with the city being densified, the street space decreases and this leads to a conflict being created between the various developers interests for the use of the space in the city. Developers have an interest in high economic growth and this means that the greenery is valued lower in the planning for sustainable urban development, unlike housing, businesses and parking spaces. The green structure lacks guidelines in the planning, which means that the greenery is difficult to justify when the planning of society is governed by an anthropocentric view. In summary, it creates difficulties when the location of the green structure must be motivated in Karlstad's growing city.
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Savoie, Robert. "A Model for Regional Technology-Based Economic Development." ScholarWorks@UNO, 2009. http://scholarworks.uno.edu/td/907.
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Technology-based economic development has been a highly sought-after objective for regions in developed and developing countries alike. The wealth created by regional knowledgebased economies like Silicon Valley is an attractive outcome. Without understanding clusterbased economic strategy, the different types of technology-based economic development approaches, the factors that dictate success or failure, and how those factors interrelate within a particular region, then the probability of success is minimal at best. Economic Development is a process and hence lends itself to a Systems Engineering approach, which was chosen as the methodology for analyzing and designing a better model for studying regions around the world to identify Factors that were both common and key to successful regional development. Each region was viewed as a system with inputs and outputs. The challenge in developing a useful system model is the development of the required Factors and Processes to be used. In the development of the model most of the Factors are internal to the system, but many may be affected by external events. The weighting (importance) of these Factors is the topic of much debate. To develop a baseline of Factors the Delphi method was used. Fortunately, a number of world-wide experts agreed to participate in one on one interviews to analyze these Factors, which in itself added a great deal to the body of knowledge of economic development beyond just the Factors. One obvious result was the essentially unanimous opinion of the group that leadership was the most important factor. A less obvious outcome, but one of equal importance was that there are two classes of regional economic development: one for mass job creation and another for the creation of a knowledge-based regional economy. Often regions undertake economic development without understanding this significant difference. While the model developed can be used for either goal it is extremely important that developers know in advance which goal is being pursued, which is also one of the critical outcomes of strong leadership. While all indications are that this model is a major improvement over current approaches, because this is a new approach until this research is followed by additional interviews, and by applying the model to actual regional technology-based economic development environments it's validity remains unproven.
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Peña, López Ismael. "Measuring digital development for policy-making: Models, stages, characteristics and causes." Doctoral thesis, Universitat Oberta de Catalunya, 2009. http://hdl.handle.net/10803/9126.
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With this work, our aim is to analyze how and why the different approaches to model and measure the Information Society have determined what is meant by the concept of access to Information and Communication Technologies and digital development. And, based on this first analysis, work on and propose a 360º digital framework that can serve policy-making while, at the same time, be able to state whether and why governments should seek to foster the development of the Information Society.Thus, the goal of this research is to identify the relevant factors that promote digital development, to define and describe - on that basis - its different stages and to explain the causes why a particular country might therefore be classified as a digital leader or a laggard and, lastly, answer whether and why governments should foster the Information Society.
To address this goal we have split our research into three main areas:
Analyzing the available tools for measuring the digital economy; and
Defining the stages of digital development, their characteristics and their causes; in particular, isolating the role of the public sector.
In the first area of research we cover the impact of ICTs, the concepts of access and the digital divide and the need to foster digital development. Our research questions in this area are:
What is "access"? What are its components?
What are the main approaches to defining access and why?
Is there any evidence that access to ICTs has had a positive or negative impact on the general socio-economic development of a country?
Why may there be a lack of access in a particular country or region, or to use a more familiar term, a "digital divide"?
Is it worthwhile for governments to attempt to foster digital development to accelerate the positive impacts of access to ICTs?
The second research theme explores, broadly and in depth, the ways in which access, digital development and the digital divide have been measured over the years, in particular through the use of composite indices. The related research questions are as follows:
What are the main models that depict digital development?
What are the approaches that these models follow to describe digital development?
What are the consequences of the different approaches followed in defining digital development models?
The third and final research theme focuses on the different stages, or phases, of digital development, their main characteristics and the reasons why digital development at the country level might be unevenly distributed.
Can we group countries according to their different levels of digital development and thus define a comprehensive model for measuring it?
What are the characteristics that enable us to cluster together countries according to their specific level of digital development?
What are the characteristics that distinguish between different levels of digital development?
Why some countries are more digitally developed than others?
The findings and reflections arising from these research questions should enable us to test the general hypothesis that guides our research. We believe that narrow institutional interests and a lack of appropriate data have led to a biased or fragmented measurement of digital development that is often focused on specific purposes. But if digital development is conceived as a continuum and described by means of a comprehensive model, then, at the country level, it can be observed that digital development happens in stages. These stages can be characterized by common features and distinguished by the scores achieved on certain key indicators. The improvement of its general economic indicators - such as income and wealth - characterizes the progression of a country along this continuum depends mainly on. Besides these basic economic aspects, if there is an appropriate Economic Incentive Regime, strong Government prioritization of ICT and a high importance afforded to ICTs in the Government's vision of the future, then digital development is much more likely to happen. In some cases, these policies may allow leapfrogging so that a country can progress faster in its digital development than would be predicted by its general level of economic development.
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Majcher, Jo-Ann Marie. "Assessing the stages of group development using children's serial group drawings." Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/28743.
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The research problem that was examined in this study was two-fold. First, was the idea that the stages of group development could be depicted in serial group drawings completed by children who had participated in structured learning groups. Second, was that by using a rating scale that was designed for this purpose, trained objective raters could classify the stages of group development from the serial drawings completed by the children.
Fifteen sets of drawings were gathered from fifteen children who had participated in different structured learning groups. These drawings were then analyzed and classified by raters who had been trained to use the rating scale. The rating scale was devised to identify the stages of group development within children's serial drawings.
Qualitative data analysis showed that the stages of group development were depicted in some of the sets of serial group drawings. Quantitative data analysis showed that raters were able to use, with limited success, the rating scale designed to classify the drawings into the stages of group development.
Many extraneous variables effected the results. These include: the unique characteristics of each child, the leadership style of each counsellor, the varying group topics, the adequacy of the rater training procedure, the objectivity of the raters, and the accuracy of the rating scale.
Due to the many extraneous variables, it is clear that methodologically this study leaves many questions unanswered. Further research is necessary to more fully investigate the idea that the stages of group development can be identified within serial group drawings completed by children who have participated in structured learning groups., If further research proves that the stages of group development can be depicted and measured using a rating scale, it will provide group counsellors with a useful tool when evaluating group development.Education, Faculty of
Educational and Counselling Psychology, and Special Education (ECPS), Department of
Graduate
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Janhager, Jenny. "User Consideration in Early Stages of Product Development : Theories and Methods." Doctoral thesis, Stockholm : Department of Machine Design, Royal Institute of Technology [Institutionen för maskinkonstruktion, Kungl. Tekniska högskolan], 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-174.
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Backlund, Daniel. "Product cost analysis in early stages of a product development process." Thesis, Mälardalens högskola, Akademin för innovation, design och teknik, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-18984.
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På en global marknad med allt tightare vinstmarginaler har fokus på produktkostnad ökat. I produktutvecklingsprocessen har ett allt större behov av förbättrade arbetssätt kring produktkostnadskalkylering uppstått för att företag skall vara konkurrenskraftiga. Produktkostnad är en väsentlig del av ett företags kostnadsmassa. Under en produktutvecklingsprocess tidiga skeden saknas ofta etablerade metoder och processer för beräkning av produktens kostnad. Speciellt svårt är det att uppskatta produktkostnad i tidiga faser av produktutvecklingsprocessen då osäkerheten kring konstruktionen är stor. Detta kan få till följd att till exempel avsaknad av vetskap kring materialkostnad eller investeringsbehov uppstår. Målet med denna uppsats är att hjälpa, utvärdera och supportera kring förbättringar av arbetssätt inom produktutvecklingsprojekten när det kommer till produktkostnadskalkylering. Syftet med detta examensarbete är att skapa en passande finansiell modell som kan användas vid val av koncept i tidiga stadier av produktutvecklingsprocessen för att säkerställa högsta möjliga lönsamhet för Volvo Construction Equipment. För att lösa detta problem så har insamling av teori i form av böcker, artiklar samt rapporter genomförts med fokus på produktutveckling och produktkostnad. Teoristudien påvisade mycket material kring produktutvecklingsprocessen men mindre kring detaljerad produktkostnadskalkylering. Den empiriska delen har genomförts i samarbete med Volvo Construction Equipment med syfte att få ökad förståelse för problemställningar i dess verkliga miljö. Från intervjuer, dokumentation samt övrig insamling så påvisades att förbättringspotential fanns kring produktkostnadskalkylering i tidiga faser av produktutvecklingsprojekt. För ytterligare ökad förståelse genomfördes en strukturerad jämförelse samt en diskussion kring respektive område av teori och empiri. Resultatet av jämförelsen visar att Volvo Construction Equipments hantering av problem korrelerar med den teori som existerar i uppsatsen. I de situationer där Volvo avviker från teorin så finns orsaker till att företaget inte väljer att följa denna. För att förbättra processen kring produktutveckling och produktkostnadskalkylering på Volvo Construction Equipment skapades en kalkylmodell. Modellen applicerades konkret i ett pågående produktutvecklingsprojekt i företaget och gav möjlighet till uppföljning av utvecklingen av produktkostnaden under de olika faserna av projektet.On a global market with tighter gross margins the focus on product cost have increased. A demand for improved methods within product cost calculations in the product development process is important to sustain competitive. Product cost is a vital part of a company’s cost base. During a product development process early stage there is often a lack of established methods and processes for calculation of the product cost. Especially difficult is it to estimate product cost in early stages of the product development process when the uncertainty around the construction of the product is big. That might lead to lack of knowledge around material cost and need of investments occur. The goal with this thesis is to help, evaluate and support around improvements within the product development projects when it comes to product cost calculation. The purpose of this thesis is to create a suitable financial model that is applicable when choosing concept in early stages of the product development process to sustain highest possible profitability for Volvo Construction Equipment. To solve this problem a collection of theory in form of books, articles and reports has been made with focus on product development and product cost. The theory part showed a lot of material around the product development process but less data around detailed product cost calculation. The empirical part has been created in cooperation with Volvo Construction Equipment with purpose to increase knowledge for problems in its natural environment. From interviews, documentations and other collection has shown that improvement potential was found for product cost calculations in early stages of product development project. For further increased understanding a structured comparison and a discussion around each area of theory and empirical data was created. The result of the comparison shows that Volvo Construction Equipment’s handling of problems correlates with the theory that exists in the thesis. To improve the process with product development and product cost calculation at Volvo Construction Equipment a calculation model was created. The model was applied in a real product development project in the company and gave opportunity for estimations of the development of the product cost during the different stages of the project.
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Tsai, Sujune. "Development of cryopreservation techniques for early stages zebrafish (Danio rerio) oocytes." Thesis, University of Bedfordshire, 2009. http://hdl.handle.net/10547/134960.
Full textAbstract:
Cryopreservation of germplasm of aquatic species offers many benefits to the fields of aquaculture, conservation and biomedicine. Although successful fish sperm cryopreservation has been achieved with many species, there has been no report of successful cryopreservation of fish embryos and late stage oocytes which are large, chilling sensitive and have low membrane permeability. In the present study, the sensitivity to chilling and toxicity of cryoprotectants of early stage zebrafish ovarian follicles were studied before designing protocols for their cryopreservation using controlled slow cooling. The effect of cryoprotectant, freezing medium, cooling rate, method for cryoprotectant removal, post-thaw incubation time and ovarian follicle developmental stage were investigated. In vitro culture method for early stage zebrafish ovarian follicles were also developed. The studies showed that stage I and II ovarian follicles are less sensitive to chilling than stage III follicles and methanol was the least toxic cryoprotectant. 4M methanol in potassium chloride (KCl) buffer was found to be the optimal cryoprotective solution and the optimum cooling rate was 4 °C/min for stage I and II follicles. Although the highest survivals after 2 h post-thawed incubation were 50.7 ± 4.0% for stage II ovarian follicles obtained with FDA+PI staining, ADP/ATP ratios of the cryopreserved follicles were significantly increased indicating increased cell death. Furthermore, in vitro culture experiments showed that there was no growth for stage I and II ovarian follicles after cryopreservation, indicating that successful cryopreservation of early stage zebrafish ovarian follicles at liquid nitrogen still remains elusive. From in vitro culture study, 90% L-15 medium at pH 9.0 containing 10 IU/ml hCG was effective for in vitro culture of stage I and II ovarian follicles. Systematic study on cryopreservation of early stage fish ovarian follicles at liquid nitrogen temperature is reported ii here for the first time. The results will provide useful information on the future development of protocol design for successful cryopreservation of early stage fish ovarian follicles.
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Costa, Nuno Mouta Faria da. "Short term toxicity of nanomaterials in different development stages of amphibians." Master's thesis, Universidade de Aveiro, 2014. http://hdl.handle.net/10773/14129.
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Mestrado em Toxicologia e EcotoxicologiaThe production of engineered nanomaterials is rising and constantly growing. The fast advances in this industry are causing the introduction of nanomaterials (NMs) into the environment, namely into aquatic ecosystems. The specific properties that these new compounds exhibit may promote higher toxicity to biota, comparatively to their bulk counterparts. Size, charge, surface area, aggregation index, among others, may dictate the availability and the degree of toxicity of NMs in aquatic environments, especially when assembled with environmental changing conditions such as pH and temperature. Amphibians are excellent bioindicators to study the risk associated with the release of NM into the aquatic environment, since they inhabit a wide variety of freshwater habitats associated with industrial contamination. The present work intended to study the toxicity of NMs to different life stages of amphibians, concerning the increase of global temperature that is currently taking place. In order to achieve this, two specific goals were determined: i) evaluate the influence of temperature in the toxicity of NMs of hidrophobically modified polyacrylic acid (HM-PAA) to tadpoles of Epidalea calamita and Pelophylax perezi. For this, tadpoles of E. calamita and P. perezi were exposed to a range of six concentrations of HM-PAA plus a control, at 20ºC and 25ºC. Results showed lethal and sublethal toxicity of HM-PAA, but a clear pattern of temperature influence in the toxicity of HM-PAA could not be unveiled; ii) assess the influence of Si-NM size and temperature in the toxicity of this NM to embryos of Pelophylax perezi. To attain this goal, embryos of P. perezi were exposed to a range of six concentrations of three differently sized Si-NMs (SM30-7nm, HS30-12nm, and TM40-22nm) plus a control, at 20ºC and 26ºC. Results obtained show lethal and sublethal toxicity caused by all the Si-NM and an increased toxicity at higher temperatures. Furthermore, it was observed that the NM presenting the lowest primary size exhibited the highest toxicity.
A produção de nanomateriais artificiais está em constante crescimento. Os rápidos avanços nesta indústria promovem a introdução de nanomateriais (NMs) no meio ambiente, nomeadamente nos ecossistemas aquáticos. As propriedades específicas que estes compostos apresentam podem promover uma maior toxicidade comparativamente aos seus correspondentes de tamanho não nano. Tamanho, carga, área superficial, índice de agregação, entre outras propriedades, podem ditar o grau de toxicidade dos NMs em ambientes aquáticos, especialmente quando combinados com as constantes mudanças de vários parâmetros ambientais, por exemplo pH e temperatura. Os anfíbios são excelentes bioindicadores para estudar o risco associado à introdução de NMs no meio aquático, uma vez que habitam uma grande variedade de habitats de água doce potencialmente contaminados com descargas industriais. O presente trabalho teve como objetivo estudar a toxicidade de NMs em diferentes estágios de vida de anfíbios, tendo em perspetiva a influência do aumento da temperatura global que atualmente afeta o planeta Terra. A fim de alcançar este objetivo, foram realizados dois estudos que pretenderam: i) avaliar a influência da temperatura na toxicidade de NMs de ácido poliacrílico hidrofobicamente modificado (HM-PAA) para girinos de Epidalea calamita e Pelophylax perezi. Para tal, girinos de E. calamita e P. perezi foram expostos a uma gama de seis concentrações de HM-PAA e a um controlo, a temperaturas de 20ºC e 25ºC. Os resultados mostram toxicidade letal e sub-letal provocada pelo HM-PAA, no entanto, não foi visível um padrão claro de influência da temperatura na toxicidade deste NM; ii) determinar a influência do tamanho de Si-NMs e da temperatura na sua toxicidade para embriões de Pelophylax perezi. Ovos de P. perezi foram expostos a uma gama de seis concentrações de três Si- NPs com diferentes tamanhos (SM30-7nm, HS30-12nm, e TM40- 22nm) e a um controlo, a temperaturas de 20ºC e 26ºC. Os resultados obtidos mostram toxicidade letal e sub-letal causadas pelos 3 NMs e um aumento da toxicidade com temperaturas mais elevadas. Mais ainda o NM com menor tamanho apresentou maior toxicidade.
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Reed, Phillip R. "An Investigation of the Relationships between Developmental Forgiveness Stages and Forgiveness Communication Strategies." Kent State University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=kent1310662318.
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Widoe, Rebecca K. "Applying stages of change theory to an acute pain situation development of the Childbirth Stages of Change Questionnaire (CSOCQ) /." Morgantown, W. Va. : [West Virginia University Libraries], 2006. https://eidr.wvu.edu/etd/documentdata.eTD?documentid=4910.
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Thesis (M.S.)--West Virginia University, 2006.Title from document title page. Document formatted into pages; contains v, 157 p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. 76-88).
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Orozco, Alina. "A spatial analysis of Norwegian spruce cone developmental stages." Thesis, Uppsala universitet, Institutionen för biologisk grundutbildning, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-425746.
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The Norway spruce Picea abies is an economically important export to the Swedish economy. There are a number of environmental and endogenous factors that impact the generation time of this species meaning that it can take 20-25 years for a tree to mature. The long generation time creates a challenge for plant breeding programs in terms of how genetic mechanisms are able to be studied as well as how quickly trees can be produced for lumber. The characterization of gene expression patterns in the context of special tissue domains is essential to understanding the underlying functions behind complex biological systems and in the case of P. abies may prove more crucial to determining the activation of genes at specific reproductive growth points. There are several techniques available for the analysis of spatial expression profiles, however, the unique high throughput nature coupled to the morphological information provided by Spatial Transcriptomics creates new opportunities for exploratory analysis. Spatial Transcriptomics offers a distinct approach to answering fundamental questions about the genetic mechanisms that regulate reproductive phase change and cone-setting in conifers. This study focuses on spatial gene expression analysis and the integration of de novo transcriptome assembly contigs to confirm the spatial context of putatively discovered genes such as DAL1, DAL2, DAL3, and DAL10 from previous studies and to potentially localize transcripts that could not previously be identified due to the inability to obtain complete transcripts. The aim is to create a workflow to identify genes that contribute to the growth patterns in the naturally occurring acrocona mutant that could prove useful to improving tree breeding programs.
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Tunström, Moa. "På spaning efter den goda staden : om konstruktioner av ideal och problem i svensk stadsbyggnadsdiskussion." Doctoral thesis, Örebro universitet, Akademin för humaniora, utbildning och samhällsvetenskap, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-116201.
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In this dissertation constructions of contemporary urban ideals are in focus, starting from the understanding that they are constructed in relation to both an idea of an urban renaissance and one ofa dissolving, or sprawling, city. The aim of the dissertation is to investigate and analyse how the city and the urban are discursively constructed in contemporary Swedish urban planning discussion. This is done by analysing articles from the Swedish Journal of Planning (Plan) and publications from the National Board of Housing, Building and Planning (Boverket) and the Urban Environment Council (Stadsmiljörådet). The main research topics are: How is the city and its history constructed? What norms are constructed about the city and the urban? How is planning and the role of the planner constructed, and what kind of knowledge and practices are emphasised? Methodologically, the dissertation is inspired by social constructivist methods, and mainly discourse theory. Applying this to the urban context means understanding urbanity and cities as constantly constructed and reconstructed discursively, even if both appear to be defined, absolute and recognisable. The analysis investigates these appearances and the meanings they are given – in this case in an urban planning context. The analysis shows that history plays an important part in both the construction of ideals and problems. Both contemporary planning and the urban ideals are conceptualised in the light of a modernist planning era, which is emphasised as the period when the “real” city was dissolved or even destroyed. An “original”, pre-modern city is constructed and guarded as the norm, and the categorisation of places appear as important. Concepts both open and defined appear as central, such as diversity, variation, identity and urbanity. The planning practice that supposedly creates the good city is ideally a sensitive and emotional practice and practitioner, in line with communicative planning theory. Binary conceptual couples structure the discourse to a high degree, resulting in polarisations such as compact/sparse, city/countryside or inner city/suburb. The problematic or contradictory, such as the suburb, is marked off from the “real” city, and an inside and outside of the good city is created. The importance of a holistic and comprehensive planning perspective is emphasized, but at the same time the urban ideal that comes out appear as a strongly normative outlook from the traditional inner city. An inner city “we” is constructed, and the suburb, the suburban and its inhabitants are seen as an Other. The dissertation also discusses some openings and contrary voices in the discourse and in other urban research indicative of an attempt to move beyond the polarisations. By questioning hierarchies and polarisations, and opening up for influence from outside of the discourse, concepts such as diversity and urbanity could be given alternative meanings instead of being used to mourn the loss of a “real”, original city or urban public space.QC 20130204
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Bown-Wilson, Dianne. "Career plateauing in older managers: A systematic literature review." Thesis, Cranfield University, 2008. http://dspace.lib.cranfield.ac.uk/handle/1826/4629.
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Economic changes have resulted in a new contextual spectrum for career development with relatively secure, hierarchical, organizational structures at one end and flatter, de-layered, insecure environments at the other. This narrative review explores the literature relating to the psychological determinants of career plateauing in older managers against such a background.
The body of literature informing this issue was analysed using the systematic review method. This is designed to produce a transparent and replicable account of how pertinent studies are located and the basis on which they are either included or rejected through use of explicit relevance, generalisability, and quality criteria. The overall outcome is a synthesis and summary of what is known about the topic, the limitations of the review, and identification of gaps in knowledge - the latter forming recommendations for future research.
The findings of this review indicate that a range of subjective determinants may play a part in career plateauing in older managers including fairly stable attributes such as personality, and individual and social identity, and more fluid factors such as attitudes, and motivation. Motivation may be driven by one or more goals including future success, present job satisfaction or ongoing personal development.
Numerous other determinants may play a role but little evidence is available as to how the range of potential influences operates at an individual level. Further qualitative research is needed into individual older managers’ experiences and how they may differ according to gender.
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Van, Staden André. "The balanced scorecard as performance measurement and personal development tool in a steel organisation / André van Staden." Thesis, North-West University, 2009. http://hdl.handle.net/10394/4801.
Full textAbstract:
The Balanced Scorecard (BSC) is a strategic management tool that provides the manager with a clear and concise picture of the business's health and progress in reaching the goals of the business (Norton & Kaplan, 1992: 71-79). The BSC is a set of financial and non-financial measures relating to a company's critical success factors. Of late the BSC was also used as a personal development tool – measuring the individual's performance towards set personal growth targets. The BSC process has been part of ArcelorMittal, Vanderbijlpark Works for many years. This process can add great value to a company if managed effectively- the question is thus: is the BSC effectively implemented in ArcelorMittal, Vanderbijlpark Works? It was decided to conduct a study to determine the status of the BSC with one main objective and two secondary objectives, namely to –
• establish whether ArcelorMittal, Vanderbijlpark Works is effectively using the
BSC tool as a performance measurement and a personal development tool (main objective);
• determine if there is a difference between the effective implementation of the
BSC as a performance management and personal development tool within the different business units within ArcelorMittal, Vanderbijlpark Works. These units are
Iron Making, Steel Making, Rolling, Engineering and Staff (Secondary objective 1): and
• determine if there is a difference between the effective implementation of the
BSC as a performance management and personal development tool between different role gradings (these roles are defined as E, F and G roles) in ArcelorMittal, Vanderbijlpark Works (Secondary objective 2). An empirical study was conducted in ArcelorMittal, Vanderbijlpark Works. A questionnaire was used as the measuring instrument and was issued via the HR Department to a target group of 724 employees. The questionnaires consisted of 25 questions divided into 2 sections to test both the effectiveness of the BSC as a performance management tool and a personal development tool. To analyse the data, descriptive statistics and frequency distributions were used and calculated in Microsoft PHStat. From these results the following conclusions were drawn.
• The BSC process is well entrenched in ArcelorMittal, Vanderbijlpark Works, but lacks overall effectiveness;
• The BSC does encourage people to self-develop, but development plans are lacking, not enough time for training is given and managers must show a real intent to develop their people. From the study and the conclusions drawn, the following recommendations were made.
• Address the issue of mistrust between the employees and their supervisory management.
• Managers should make allowance for individuals to make mistakes.
• Encourage innovation in the organisation.
• More effort should be applied to translate the company strategic objectives into workable (and measurable) KPI 's at the lower levels of the organisation.
• ArcelorMittal should make a concerned effort to allow more time for training and self-development during normal working hours.
• Revisit all KPI's for weight allocation. All the departments and all the levels in the
organisation see this as a drawback of the BSC system.
• Test the applicability of the KPis. Ensure that the KPis on the BSC are clear and that these reflect the effort the company requires form the individual.
• Allow more participation of the individual during the compilation of the BSC (this will improve buy-in).
• The E-role level communicates very well downwards to the lower levels in the organisation. Take key learning aspects from this group, and skill the F-role and
G-role levels to the same extent.Thesis (M.B.A.)--North-West University, Vaal Triangle Campus, 2010.