Academic literature on the topic 'St John's Wort'

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Journal articles on the topic "St John's Wort"

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Mullaicharam, AR, and Nirmala Halligudi. "St John's wort (Hypericum perforatum L.): A Review of its Chemistry, Pharmacology and Clinical properties." International Journal of Research In Phytochemical And Pharmacological Sciences 1, no. 1 (June 30, 2018): 5–11. http://dx.doi.org/10.33974/ijrpps.v1i1.7.

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St John's wort (also known as hypericum, millepertuis) is Hypericum perforatum L., Hypericaceae, an herbaceous perennial plant native to Europe and Asia, and which has been introduced into the United States where it has naturalized (38). The chemical composition of St. John's wort has been well-studied. Documented pharmacological activities, including antidepressant, antiviral, and antibacterial effects, provide supporting evidence for several of the traditional uses stated for St John's wort. Many pharmacological activities appear to be attributable to hypericin and to the flavanoid constituents; hypericin is also reported to be responsible for the photosensitive reactions that have been documented for St. John's wort. This systematic review overviews the literature on the use of St. John’s Wort for chemistry, pharmacology and clinical properties.
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Field, Howard L., Daniel A. Monti, Jeffrey M. Greeson, and Elisabeth J. S. Kunkel. "St. John's Wort." International Journal of Psychiatry in Medicine 30, no. 3 (September 2000): 203–19. http://dx.doi.org/10.2190/pbfd-lwb4-u8cg-53c9.

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Salzman, Carl. "St. John's Wort." Harvard Review of Psychiatry 5, no. 6 (January 1998): 333–35. http://dx.doi.org/10.3109/10673229809003582.

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Gupta, R. K., and H. J. M�ller. "St. John's Wort." European Archives of Psychiatry and Clinical Neuroscience 253, no. 3 (June 1, 2003): 140–48. http://dx.doi.org/10.1007/s00406-003-0417-6.

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Frommenwiler, Débora A., Eike Reich, Sidney Sudberg, Maged H. M. Sharaf, Anton Bzhelyansky, and Ben Lucas. "St. John's Wort versus Counterfeit St. John's Wort: An HPTLC Study." Journal of AOAC INTERNATIONAL 99, no. 5 (September 1, 2016): 1204–12. http://dx.doi.org/10.5740/jaoacint.16-0170.

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Abstract Hypericum perforatum L. is the most commonly used herb for treating depression. Due to the popularity of this botanical, there is a potential for economically driven adulteration of St. John's wort (SJW) products. The goal of this study was to investigate SJW ingredients suspected to be adulterated based on simple preliminary HPTLC tests. Commercial samples were analyzed by HPTLC following the United States Pharmacopeia (USP) monograph methodology, with additional visualization under white light. A number of these samples presented odd methanolic solution colors and unconventional HPTLC fingerprints, suggesting the presence of other species and/or extraneous polar additives. To achieve identification and separation of the polar additives, a new reversed-phase HPTLC method was developed. The adulterants were identified as synthetic dyes in the amounts of 0.51 to 1.36% by weight. Identities of the dyes were confirmed by scanning densitometry and HPTLC-MS. A modified USP method with additional detection mode permitted the identification of eight SJW samples adulterated with dyes and six others with flavonoid fingerprints different from those specified by USP from a total of 37 samples of dry extracts, finished products, and bulk raw herb. A decision flowchart is proposed to guide the detection of adulteration of SJW in a systematic fashion.
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Redvers, A., R. Laugharne, G. Kanagaratnam, and G. Srinivasan. "How many patients self-medicate with St John's wort?" Psychiatric Bulletin 25, no. 7 (July 2001): 254–56. http://dx.doi.org/10.1192/pb.25.7.254.

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Aims and MethodSt John's wort is popularly taken as a herbal remedy, but it interacts with prescribed drugs. The aim of this survey was to estimate the prevalence of patients self-medicating with St John's wort. All new referrals to a community mental health team over 5 months were asked about any use of St John's wort.ResultsFifteen patients, of 101, had taken St John's wort at some time and of those seven were currently taking it. Patients who used St John's wort tended to be younger and female. Only nine of the 15 patients took it for depressive symptoms and none had received medical advice. One patient was taking an interacting medication.Clinical ImplicationsA significant number of patients are taking St John's wort. In order to prevent drug interactions, doctors should ask all patients whether they use it, especially young women who may be on the contraceptive pill. Patients need better education about its risks and benefits and it should be taken with medical advice.
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Schneck, Christopher. "St. John's Wort and Hypomania." Journal of Clinical Psychiatry 59, no. 12 (December 15, 1998): 689. http://dx.doi.org/10.4088/jcp.v59n1208d.

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Bilia, Anna Rita, Sandra Gallori, and Franco F. Vincieri. "St. John's wort and depression." Life Sciences 70, no. 26 (May 2002): 3077–96. http://dx.doi.org/10.1016/s0024-3205(02)01566-7.

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Brown, Thomas M. "Acute St. John's wort toxicity." American Journal of Emergency Medicine 18, no. 2 (March 2000): 231–32. http://dx.doi.org/10.1016/s0735-6757(00)90030-5.

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LEARD-HANSSON, JAN, and Laurence Guttmacher. "St. John's Wort for Depression." Clinical Psychiatry News 36, no. 12 (December 2008): 9. http://dx.doi.org/10.1016/s0270-6644(08)70799-9.

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Dissertations / Theses on the topic "St John's Wort"

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Hicks, Stephen Michael. "St. John's wort for women's health." Thesis, University of Reading, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.271568.

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Chandrasekera, Dhammitha Himali. "Analytical investigations of St. John's wort herbal preparations." Thesis, University of London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.483534.

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Songhurst, Leah. "The medicalisation of happiness : a history of St. John's wort." Thesis, University of Exeter, 2010. http://hdl.handle.net/10036/3060.

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This thesis explores the histories of mild to moderate depression and the use of over the counter (OTC) St. John’s wort (St. John’s wort) during the 1990s. In doing so it not only investigates the diagnosis and definition of mental illnesses, it also raises questions about the interface between conventional and alternative medicine. Using a variety of printed sources, including popular media articles, scientific and medical journal publications, and St. John’s wort self-help books, a number of historical themes are explored. This thesis takes issue with existing medical historical studies of depression. Firstly it is argued that they have presented progressive depression histories. Secondly, it is suggested that they have retrospectively diagnosed depression on the basis of similar symptoms. It is therefore argued that illness is specific to the time in which it exists and should be understood within its own historical timeframe. During the 1990s standardised St. John’s wort was promoted as a natural and safe remedy. Adverts and media reports also highlighted the fact that it had a long medical history. Although this thesis establishes that the plant has been traditionally used to treat physical illnesses, it seems that a growing distrust of conventional antidepressants, combined with an established interest in alternative medicine, encouraged some lay people to use the remedy to treat mild mood disorders. It is further argued that lay people have a history of self-treating minor mental illnesses using preparatory and OTC remedies such as preparatory nerve tonics. Not only did lay people desire autonomous treatments, it also seems that standardised St. John’s wort provided a functional role as an OTC remedy. By the 1990s the concepts of responsible self-care and self-treatment were being actively encouraged by medical authorities. Therefore this thesis reclassifies the passive mild to moderately depressed patient as an active consumer. Following an analysis of the popular media it is suggested that the 1990s coverage of depression and its treatments was confusing. Indeed, depression and its treatment with conventional medicines and St. John’s wort were sometimes presented as part of a wider life style choice. Finally, it is argued that by the 1990s standardised St. John’s wort received the same scientific and medical scrutiny as conventional medicines. It is therefore suggested that the remedy represents a situation in which the boundaries between conventional and alternative medicines have become increasingly indistinguishable.
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Saiyudthong, Somrudee. "Mechanisms underlying the antidepressant properties of St. John's wort (Hypericum perforatum)." Thesis, University of Nottingham, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.275319.

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Gray, Dean E. "Chemical quality in two medicinal plants : St. John's wort and purple coneflower /." free to MU campus, to others for purchase, 2000. http://wwwlib.umi.com/cr/mo/fullcit?p9974634.

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Wild, Tracy Joy. "Pharmaceutical analysis and aspects of the quality control of St. John's Wort products." Thesis, Rhodes University, 2003. http://hdl.handle.net/10962/d1003282.

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Most complementary medicines contain a multitude of chemical components, some of which are claimed to contribute to the biological activity of such products. Use of complementary medicines for preventative and therapeutic purposes is increasing rapidly worldwide. Unfortunately, although control of these products is essential to ensure quality, safety, and efficacy, the quality control of most herbal preparations is currently poor to non-existent, with little or no safety and efficacy data required to support the marketing and use of these products. The objective of this study was therefore to develop suitable analytical methods to qualitatively and quantitatively analyse the relevant components (rutin, isoquercitrin, hyperoside, quercitrin, quercetin, kaempferol, hypericin, pseudohypericin and hyperforin) in St John's Wort dosage forms for quality control purposes. A gradient HPLC method using a Luna 5·mC₁₈(2) 150 x 2.00mm internal diameter (i.d.) column and UV detection, was developed for the separation of six of the relevant flavonoid compounds in St John's Wort, namely rutin, isoquercitrin, hyperoside, quercitrin, quercetin and kaempferol. The development process involved a systematic investigation of gradient conditions, flow rate, and temperature. This method was subsequently applied to assay selected commercially available St John's Wort products. This system provided the necessary accuracy, precision and reproducibility and was associated with several advantages when compared to using standard bore (4.60 mm i.d.) HPLC columns. The method developed is currently the only known method that separates all six relevant flavonoids in a reasonable run time (less than 20 minutes). It is also one of the few methods that has sufficient separation between rutin, isoquercitrin and hyperoside. A qualitative method for the fingerprinting of flavonoid components was also developed, using capillary electrophoresis (CE). CE is a rapidly growing powerful analytical technique for the separation of charged compounds. Micellar electrokinetic chromatography (MEKC) is a very powerful electrophoretic technique that is capable of selectively resolving both neutral and ionic solutes in a single run. A MEKC method suitable for the separation and determination of various flavonoid constituents used as marker compounds in Hypericum perforatum was developed. Investigations into the effect of pH, ionic strength, applied voltage and capillary dimensions on separation were performed. The optimised method was then applied to qualitatively analyse various St John's Wort products on the market. This method was found to be advantageous in that it was simple, cost-effective, required minimal sample preparation and utilised very small quantities of sample. Due to the vast differences in chemical properties between the various marker and active components in St John's Wort, it was necessary to develop separate analytical methods for the flavonoids and for the other three relevant compounds (hypericin, pseudohypericin and hyperforin). An isocratic HPLC method using a Luna 5·mC₁₈(2) 150 x 2.00mm (i.d.) column and UV detection was developed for the separation of hypericin, pseudohypericin and hyperforin. The development process involved a systematic investigation of buffer molarity, mobile phase composition, pH, flow rate, and temperature. This method was subsequently applied to assay selected commercially available St John's Wort products on the South African market. This system also provided the necessary accuracy, precision and reproducibility, as well as the advantages associated with the use of a narrow bore column as opposed to the use of the more commonly used wider bore columns. This method was validated and used to quantitate these three compounds in various commercial St John's Wort products. By applying this method to liquid chromatography – tandem mass spectrometry (LC-MS-MS), qualitative analyses of the same products was performed to obtain confirmation of the quantitative HPLC results. Mass spectrometry is a powerful detection tool that is more selective and specific than many detection systems used with HPLC. Natural medicines usually constitute a multitude of constituents with much potential interference. In this regard LC-MS-MS is a powerful tool, with its ability to unequivocally identify target analytes regardless of the presence of interferences or complex matrices. ESI-MS-MS was used for the qualitative analysis of the content of the naphthodianthrones and hyperforin in the respective tablet products assayed with HPLC. LC-MS-MS analyses were performed in order to identify the constituents and to verify the specificity of the HPLC method. High inter-product and inter-batch variability was observed for all nine compounds assayed. These quantitative results were confirmed with the respective qualitative analyses. This study confirms the need for strict quality control of herbal medicinal products commercially available to consumers.
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Wu, Chung-Hsuen. "Access factors associated with the use of St. John's wort among adults with depressive symptoms." Online access for everyone, 2006. http://www.dissertations.wsu.edu/Thesis/Spring2006/c%5Fwu%5F042806.pdf.

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Murch, Susan Jean. "Identification and characterization of melatonin in medicinal plants, feverfew, Huang-qin and St. John's Wort." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0017/NQ55632.pdf.

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Bell, Edward C. Ravis William R. "The effects of St. John's Wort on the pharmacokinetics of corticosteroid and non-steroidal drug preparations." Auburn, Ala., 2005. http://repo.lib.auburn.edu/2005%20Summer/doctoral/BELL_EDWARD_47.pdf.

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Jiang, Xuemin. "Effect of herbal medicines on the pharmacokinetics and pharmacodynamics of Warfarin in healthy subjects." University of Sydney. Pharmacy, 2004. http://hdl.handle.net/2123/651.

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Herbal medicines are widely used in our community. A survey of Australian consumers indicated that 60% had used complementary and/or alternative medicines in the past year with the majority not informing their doctor that they were using herbal medicines. Little is known about the potentially serious consequences of interactions between herbal and conventional medicines. Warfarin has an important role in treating people with heart disease, yet it has a narrow therapeutic range, is highly bound to plasma proteins, and is metabolised by cytochrome P450. This creates the potential for life-threatening interactions with other drugs and foods leading to excessive bleeding. Hence, warfarin is one of the most frequently investigated drugs for interaction studies. Early clinical reports suggest that there exists the potential for an interaction between warfarin and four herbal medicines: St John�s wort, ginseng, ginkgo and ginger. However, these herb-drug combinations have never been conclusively studied. The two clinical studies conducted as part of this research had an identical study design. Twenty-four healthy male subjects were recruited into the two separate studies. This was an open label, three-way crossover randomised study in twelve healthy male subjects, who received a single 25 mg dose of warfarin alone or after 14 days pre-treatment with St John�s wort, or 7 days pre-treatment with ginseng. Dosing with St John�s wort or ginseng was continued for 7 days after administration of the warfarin dose in study I or who received a single 25 mg dose of warfarin alone or after 7 days pre-treatment with recommended doses of ginkgo or ginger from single ingredient products of known quality. Dosing with ginkgo or ginger was continued for 7 days after administration of the warfarin dose in study II. Platelet aggregation, international normalised ratio (INR) of prothrombin time, warfarin enantiomer protein binding, warfarin enantiomer concentrations in plasma and S-7-hydroxywarfarin concentration in urine were measured in both studies. Statistical comparisons were made using ANOVA and 95% confidence interval (CI) for mean value and 90% CI for geometric mean ratio value are reported. n study I, the mean (95% CI) apparent clearance of S-warfarin after warfarin alone or with St John�s wort or ginseng were, respectively, 198 (174 � 223) ml/h, 269 (241 � 297) ml/h and 220 (201 � 238) ml/h. The respective apparent clearances of R-warfarin were 110 (94 � 126) ml/h, 142 (123 � 161) ml/h and 119 (106 � 131) ml/h. The mean ratio of apparent clearance for S-warfarin was 1.29 (1.16-1.46) and for R-warfarin was 1.23 (1.11-1.37) when St John�s wort was co-administered. The mean ratio of AUC0-168 of INR was 0.79 (0.70 - 0.95) when St John�s wort was co-administered. The urinary excretion ratio of S-7-hydroxywarfarin after administration of warfarin alone was 0.04 (0.03 � 0.06) mg/h and there was no significant difference following treatment with either St John�s wort 0.03 (0.02 � 0.04) mg/h or ginseng 0.03 (0.02 � 0.04) mg/h. The ratio of geometric means for S-7-hydroxywarfarin UER was 0.82 (0.61-1.12) for St John�s wort, and 0.68 (0.50-0.91) for ginseng. St John�s wort and ginseng did not affect the apparent volumes of distribution or protein binding of warfarin enantiomers. In study II, the mean (95% CI) apparent clearance of S-warfarin after warfarin alone, with ginkgo or ginger were 189 (167 � 210) ml/h, 200 (173 � 227) ml/h and 201 (171 � 231) ml/h, respectively. The respective apparent clearances of R-warfarin were 127 (106 � 149) ml/h, 126 (111 � 141) ml/h and 131 (106 � 156) ml/h. The mean ratio of apparent clearance for S-warfarin was 1.05 (0.98 -1.12) and for R-warfarin was 1.00 (0.93 -1.08) when co-administered with ginkgo. The mean ratio of AUC0-168 of INR was 0.93 (0.81 -1.05) when co-administered with ginkgo. The mean ratio of apparent clearance for S-warfarin was 1.05 (0.97 -1.13) and for R-warfarin was 1.02 (0.95 -1.10) when co-administered with ginger. The mean ratio of AUC0-168 of INR was 1.01 (0.93 -1.15) when co-administered with ginger. The urinary excretion ratio (UER) of S-7-hydroxywarfarin after administration of warfarin alone was 0.04 (0.03 � 0.05) mg/h and there was no significant difference following treatment with either ginkgo 0.04 (0.03 � 0.04) mg/h or ginger 0.03 (0.02 � 0.04) mg/h. The ratio of geometric means for S-7-hydroxywarfarin UER was 1.07 (0.69-1.67) for ginkgo, and 1.00 (0.64-1.56) for ginger. Ginkgo and ginger did not affect the apparent volumes of distribution or protein binding of either S-warfarin or R-warfarin. In conclusion, St John�s wort significantly induced the apparent clearance of both S-warfarin and R-warfarin, which in turn resulted in a significant reduction in the pharmacological effect of rac-warfarin. Ginseng, ginkgo and ginger at recommended doses affect neither clotting status, nor the pharmacokinetics or pharmacodynamics of either S-warfarin or R-warfarin in healthy subjects.
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Books on the topic "St John's Wort"

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St. John's wort. Shaftesbury, Dorset: Element, 1999.

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Secrets of St. John's Wort. New York: St. Martin's Paperbacks, 1998.

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St. John's wort: Nature's blues buster. Garden City Park, N.Y: Avery Pub. Group, 1998.

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Beat depression with St. John's wort. Rocklin, CA: Prima Pub., 1997.

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St. John's wort: Your natural prozac. London: Thorsons/HarperCollins, 1998.

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Pedersen, Stephanie. St. John's wort: Improving moods & immunity. New York, NY: DK Pub., 2000.

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St. John's wort: The mood enhancing herb. Loveland, Colo: Interweave Press, 1997.

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St. John's wort: The herbal way to feeling good. New York, NY: HarperCollins, 1998.

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Brown, Kathleen. An herbalist's guide to growing & using St. John's wort. Pownal, Vt: Storey Books, 1999.

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Bratman, Steven. Everything you need to know about St. John's wort and depression. Rocklin, CA: Prima Health, 1999.

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Book chapters on the topic "St John's Wort"

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Krasowski, Matthew D., and John L. Blau. "Drug Interactions with St. John's Wort." In Herbal Supplements, 273–90. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2010. http://dx.doi.org/10.1002/9780470910108.ch12.

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Dostalek, Miroslav, and Anna-Katarina Stark. "St John's Wort (Hypericum Perforatum L.)." In Metabolism of Drugs and Other Xenobiotics, 583–610. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527630905.ch21.

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Reuter, Hans D. "Chemistry and Biology ofHypericum perforatum(St. John's Wort)." In ACS Symposium Series, 287–98. Washington, DC: American Chemical Society, 1998. http://dx.doi.org/10.1021/bk-1998-0691.ch020.

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Mannila, Mari, Qingyong Lang, Chien M. Wai, Yanyan Cui, and Catharina Y. W. Ang. "Supercritical Fluid Extraction of Bioactive Components from St. John's Wort (Hypericum perforatumL.) andGinkgo biloba." In ACS Symposium Series, 130–44. Washington, DC: American Chemical Society, 2003. http://dx.doi.org/10.1021/bk-2003-0860.ch009.

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Murch, S. J., S. D. S. Chiwocha, and P. K. Saxena. "Development of Micropropagation Technologies for St. John's wort (Hypericum perforaturm L.): Relevance on Application." In ACS Symposium Series, 161–70. Washington, DC: American Chemical Society, 2002. http://dx.doi.org/10.1021/bk-2002-0829.ch013.

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Krist, Sabine. "St. John’s Wort Oil." In Vegetable Fats and Oils, 719–23. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-30314-3_111.

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Čellárová, E., and K. Bruňaková. "Somaclonal Variation in Hypericum perforatum (St. John’s Wort)." In Biotechnology in Agriculture and Forestry, 267–79. Berlin, Heidelberg: Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-642-61081-3_18.

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Kirakosyan, Ara, Donna M. Gibson, and Peter B. Kaufman. "The Production of Dianthrones and Phloroglucinol Derivatives in St. John’s Wort." In Bioactive Molecules and Medicinal Plants, 149–64. Berlin, Heidelberg: Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-74603-4_7.

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Nöldner, Michael. "Comparative preclinical antidepressant activity of isolated constituents." In St. John’s Wort and its Active Principles in Depression and Anxiety, 73–84. Basel: Birkhäuser Basel, 2005. http://dx.doi.org/10.1007/3-7643-7338-5_7.

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Yazaki, K., and T. Okuda. "Hypericum erectum Thunb. (St. John’s Wort): In Vitro Culture and the Production of Procyanidins." In Medicinal and Aromatic Plants VI, 167–78. Berlin, Heidelberg: Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-57970-7_11.

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Conference papers on the topic "St John's Wort"

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Lekbangpong, Narongsak, Theera Srisawat, Apirat Wanichsombat, and Jirapond Muangprathub. "The Control Model for Environmental Factor Effecting on Growth of St. John's Wort." In 2019 16th International Joint Conference on Computer Science and Software Engineering (JCSSE). IEEE, 2019. http://dx.doi.org/10.1109/jcsse.2019.8864201.

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Goey, Andrew K. L., Irma Meijerman, Hilde Rosing, Marianne Keessen, Jos H. Beijnen, and Jan H. M. Schellens. "Abstract 761: Phase I interaction study of docetaxel with supplementation of St. John's wort." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-761.

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Melissa L Brechner and Louis D Albright. "Optimizing Secondary Metabolites of Hypericum perforatum or St. John's wort Through Ultra-violet Light Application." In 2008 Providence, Rhode Island, June 29 - July 2, 2008. St. Joseph, MI: American Society of Agricultural and Biological Engineers, 2008. http://dx.doi.org/10.13031/2013.24638.

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Keksel, N., H. Bußmann, M. Unger, J. Drewe, S. Franken, and H. Häberlein. "Influence of the St. John's Wort extract Ze117 on membrane fluidity, signal transduction, and mobility of the β1-adrenergic receptor." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608588.

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Zahner, C., E. Kruttschnitt, J. Uricher, M. Lissy, M. Hirsch, S. Nicolussi, S. Krähenbühl, and J. Drewe. "No clinically relevant interactions of St. John’s wort extract Ze 117 low in hyperforin with cytochrome P450 enzymes and P-glycoprotein." In 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP. © Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-3400128.

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Möller, J., E. Raskopf, O. Greinert, G. Zadoyan, S. Schleicher, K. Shah-Hosseini, C. Kolb, et al. "St. John´s wort in a large epidemiological study on the use of herbal medicinal products." In 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP. © Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-3400130.

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Galochkina, Tatiana. "Word formative structure of words with the root lěp- in Old Russian written records." In 6th International e-Conference on Studies in Humanities and Social Sciences. Center for Open Access in Science, Belgrade, 2020. http://dx.doi.org/10.32591/coas.e-conf.06.10121g.

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System of derivational morphology of the Old Russian language has its own characteristics based on the origin of the book vocabulary, which consisted mainly of Proto-Slavic words and calques from Greek words. The main morphological way of word formation was the heritage of the Proto-Slavic language, which developed together with the formation of morphemes as a language unit. Active derivation took place during the formation of the Old Russian book vocabulary. During this period an uninterrupted process began the creation of book translations from the Greek into Church Slavonic. The ancient scribes made extensive use of Greek words calquing, which especially intensified the creation of compound words. Compound words were formed according to the models of Greek composites, but using Russian morphemes. As a result of this process, the lexical fund of the literary language was created, which included words with the root *lěp-. Such words are contained in ancient Russian written records (“Life of St. Sava the Sanctified”, composed by St. Cyril Skifopolsky, “The Life of St. Andrew the Fool”, “The Chronicle” by John Malalas, “The Chronicle” by George Amartol, “History of the Jewish War” by Josephus Flavius, Christianopolis (Acts and Epistles of the Apostles), Uspensky Сollection of XII–XIII centuries etc.). In the article will be considered the word formative structure of words with the root lěp-.
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8

Galochkina, Tatiana. "Word formative structure of words with the root lěp- in Old Russian written records." In 6th International e-Conference on Studies in Humanities and Social Sciences. Center for Open Access in Science, Belgrade, 2020. http://dx.doi.org/10.32591/coas.e-conf.06.10121g.

Full text
Abstract:
System of derivational morphology of the Old Russian language has its own characteristics based on the origin of the book vocabulary, which consisted mainly of Proto-Slavic words and calques from Greek words. The main morphological way of word formation was the heritage of the Proto-Slavic language, which developed together with the formation of morphemes as a language unit. Active derivation took place during the formation of the Old Russian book vocabulary. During this period an uninterrupted process began the creation of book translations from the Greek into Church Slavonic. The ancient scribes made extensive use of Greek words calquing, which especially intensified the creation of compound words. Compound words were formed according to the models of Greek composites, but using Russian morphemes. As a result of this process, the lexical fund of the literary language was created, which included words with the root *lěp-. Such words are contained in ancient Russian written records (“Life of St. Sava the Sanctified”, composed by St. Cyril Skifopolsky, “The Life of St. Andrew the Fool”, “The Chronicle” by John Malalas, “The Chronicle” by George Amartol, “History of the Jewish War” by Josephus Flavius, Christianopolis (Acts and Epistles of the Apostles), Uspensky Сollection of XII–XIII centuries etc.). In the article will be considered the word formative structure of words with the root lěp-.
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9

Brickner, Robert H. "Behind the Scenes: Historic Agreement to Develop U.S. Virgin Islands’ First Alternative Energy Facilities." In 18th Annual North American Waste-to-Energy Conference. ASMEDC, 2010. http://dx.doi.org/10.1115/nawtec18-3516.

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In the summer of 2009, Governor John P. DeJongh, Jr. announced that the Virgin Islands Water and Power Authority (WAPA) had just signed two 20-year Power Purchase Agreements, and the Virgin Islands Waste Management Authority (VIWMA) had signed two 20-year Solid Waste Management Services Agreements with affiliates of Denver-based Alpine Energy Group, LLC (AEG) to build, own, and operate two alternative energy facilities that will serve the residents of St. Croix, St. John, and St. Thomas. The alternative energy facilities, to be built on St. Croix and St. Thomas, have a projected cost of $440 million and will convert an estimated 146,000 tons per year of municipal solid waste into refuse-derived fuel (RDF) using WastAway Services® technology, which will be combined with petroleum coke as fuel in fluidized bed combustion facilities to generate steam and electric power. These sustainable projects will provide 33 MW of electric power to St. Thomas and St. John and 16 MW of electric power to St. Croix, and will help to provide long-term cost stability for electric power and solid waste management in the Territory. Construction is expected to start in spring 2010 with an anticipated completion date during the fourth quarter of 2012. This procurement is a significant achievement for the U.S. Virgin Islands. When the projects are fully implemented, they will allow the Territory to reduce its dependence on oil, recover the energy value and certain recyclable materials from its municipal solid waste, and divert this waste from landfill. Since VIWMA has the responsibility to collect and/or dispose of solid waste year-round, having a system incorporating multiple solid waste processing lines and an adequate supply of spare parts on hand at all times is crucial to meeting the daily demands of waste receiving and processing, and RDF production. Also, with the location of the US Virgin Islands in a hurricane zone, and with only one or two combustion units available in each Project, the ability to both stockpile waste pre-RDF processing and store the produced RDF is very important. Gershman, Brickner & Bratton, Inc. (GBB)’s work has included a due diligence review of the Projects and providing professional support in VIWMA’s negotiations with AEG. GBB’s initial primary assignment centered on reviewing the design and operations of the RDF processing systems that will be built and operated under the respective Service Contracts. VIWMA needed to undertake a detailed technical review of the proposed RDF processing system, since this was the integration point of the waste collection system and waste processing/disposal services. GBB, in association with Maguire, was requested to provide this review and present the findings and opinions to VIWMA. In the completion of this effort, which included both a technical review and participation in negotiations to advance the Service Contracts for the Projects, GBB made direct contact with the key equipment suppliers for the Projects proposed by AEG. This included Bouldin Corporation, the primary RDF processing system supplier, with its patented WastAway technology, and Energy Products of Idaho, the main thermal processing equipment supplier, with its fluidized bed combustion technology and air pollution control equipment. Additionally, since the combustion systems for both Projects will generate an ash product that will require marketing for use and/or disposal over the term of the Service Contracts, GBB made contact with LA Ash, one of the potential subcontractors identified by AEG for these ash management services. Due to the nature of the contract guarantees of VIWMA to provide 73,000 tons per year of Acceptable Waste to each Project for processing, VIWMA authorized GBB to perform a current waste stream characterization study. Part of this effort included waste sorts for one week each in February 2009 on St. Croix and March 2009 on St. Thomas, with the results shared with VIWMA and AEG, as compiled. The 2009 GBB waste stream characterization study incorporated historical monthly waste weigh data from both the Bovoni and Anguilla Landfills that were received from VIWMA staff. The study has formed a basis for continuing to augment the waste quantity information from the two landfills with the additional current monthly results compiled by VIWMA staff going forward following the waste sorts. The final GBB report was published in December 2009 and includes actual USVI landfill receipt data through August 31, 2009. The information contained in this document provides the underpinnings to allow for better tracking and analysis of daily, weekly and monthly waste quantities received for recycling, processing and disposal, which are important to the overall waste processing system operations, guarantees and cost projections. GBB’s annual projections are that the total waste on St. Croix is currently over 104,000 tons per year and over 76,000 tons per year on St. Thomas. The thermal processing technology selected for both Projects is a fluidized bed process, employing a heated bed of sand material “fluidized” in a column of air to burn the fuel — RDF and/or Pet Coke. As such, the solid waste to be used in these combustion units must be size-reduced from the myriad of sizes of waste set out at the curb or discharged into the large roll-off boxes or bins at the many drop-off sites in the US Virgin Islands. While traditional RDF would typically have several days of storage life, the characteristics of the pelletized RDF should allow several weeks of storage. This will be important to having a sound and realistic operating plan, given the unique circumstances associated with the climate, waste moisture content, island location, lack of back-up disposal options and downtime associated with the Power Generation Facility. During the negotiations between AEG and VIWMA, in which GBB staff participated, in addition to RDF and pelletized RDF as the waste fuel sources, other potential fuels have been discussed for use in the Projects and are included as “Opportunity Fuels” in the Service Contracts. These Opportunity Fuels include ground woody waste, dried sludges, and shredded tires, for example. Therefore, the flexibility of the EPI fluidized bed combustion boilers to handle multi-fuels is viewed as an asset over the long term, especially for an island location where disposal options are limited and shipping materials onto and off of each island is expensive. This presentation will provide a unique behind-the-scenes review of the process that led to this historic agreement, from the due diligence of the proposed technologies, to implementation planning, to the negotiations with the contractor. Also discussed will be the waste characterization and quantity analysis performed in 2009 and the fast-track procurement planning and procurement of construction and operating services for a new transfer station to be sited on St. Croix.
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10

Nicoll, Ryan S., Charles F. Wood, and André R. Roy. "Comparison of Physical Model Tests With a Time Domain Simulation Model of a Wave Energy Converter." In ASME 2012 31st International Conference on Ocean, Offshore and Arctic Engineering. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/omae2012-83699.

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Development of wave energy conversion systems may yield many key benefits for society such as the production of electrical power or fresh water for remote communities. However, complex ocean dynamics make it difficult for technology developers to not only address the stability and survivability of their systems, but also to establish energy conversion rates that are fundamental to proving economic viability. Building physical prototypes presents many challenges in terms of cost, accessible facilities, and time requirements. The use of accurate numerical modelling and computer simulation can help guide design and significantly reduce the number of physical prototype tests required and as a result play a primary role in the development of wave energy conversion systems that have to operate in challenging marine environments. SurfPower is an ocean wave energy converter (WEC) that converts wave motion into useful energy through surge and heave motion of a point absorber. The system pumps seawater into a high pressure hydraulic network that generates electricity via a turbine or freshwater via desalination at a facility onshore. The system is nonlinear due to the significant change in draft and mooring reaction load through the energy capture cycle of the device. This makes the use of nonlinear time domain simulation ideal for analysis and design of the system. Furthermore, utilizing a simplified nonlinear hydrodynamic model available in the time domain results in a practical early-stage design tool for system refinement. The focus of this work is to compare the results of scale model testing completed at the Institute for Ocean Technology in St. John’s, Newfoundland, with results produced from an equivalent system simulated in the time domain simulation software ProteusDS. The results give an assessment of the range of error that can be used to assess other experiments of the SurfPower WEC at full scale.
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Reports on the topic "St John's Wort"

1

Branda, Richard F. Effects of St. John's Wort and Vitamin E on Breast Cancer Chemotherapeutic Agents. Fort Belvoir, VA: Defense Technical Information Center, May 2003. http://dx.doi.org/10.21236/ada416778.

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2

Branda, Richard F. Effects of St. John's Wort and Vitamin E on Breast Cancer Chemotherapeutic Agents. Fort Belvoir, VA: Defense Technical Information Center, May 2002. http://dx.doi.org/10.21236/ada406841.

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3

Branda, Richard F. Effects of St. John's Wort and Vitamin E on Breast Cancer Chemotherapeutic Agents. Fort Belvoir, VA: Defense Technical Information Center, May 2004. http://dx.doi.org/10.21236/ada430570.

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