Academic literature on the topic 'SRFΔ5'

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Journal articles on the topic "SRFΔ5"

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Belaguli, Narasimhaswamy S., Wei Zhou, Thuy-Hanh T. Trinh, Mark W. Majesky, and Robert J. Schwartz. "Dominant Negative Murine Serum Response Factor: Alternative Splicing within the Activation Domain Inhibits Transactivation of Serum Response Factor Binding Targets." Molecular and Cellular Biology 19, no. 7 (July 1, 1999): 4582–91. http://dx.doi.org/10.1128/mcb.19.7.4582.

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ABSTRACT Primary transcripts encoding the MADS box superfamily of proteins, such as MEF2 in animals and ZEMa in plants, are alternatively spliced, producing several isoformic species. We show here that murine serum response factor (SRF) primary RNA transcripts are alternatively spliced at the fifth exon, deleting approximately one-third of the C-terminal activation domain. Among the different muscle types examined, visceral smooth muscles have a very low ratio of SRFΔ5 to SRF. Increased levels of SRFΔ5 correlates well with reduced smooth muscle contractile gene activity within the elastic aortic arch, suggesting important biological roles for differential expression of SRFΔ5 variant relative to wild-type SRF. SRFΔ5 forms DNA binding-competent homodimers and heterodimers. SRFΔ5 acts as a naturally occurring dominant negative regulatory mutant that blocks SRF-dependent skeletal α-actin, cardiac α-actin, smooth α-actin, SM22α, and SRF promoter-luciferase reporter activities. Expression of SRFΔ5 interferes with differentiation of myogenic C2C12 cells and the appearance of skeletal α-actin and myogenin mRNAs. SRFΔ5 repressed the serum-induced activity of the c-fos serum response element. SRFΔ5 fused to the yeast Gal4 DNA binding domain displayed low transcriptional activity, which was complemented by overexpression of the coactivator ATF6. These results indicate that the absence of exon 5 might be bypassed through recruitment of transcription factors that interact with extra-exon 5 regions in the transcriptional activating domain. The novel alternatively spliced isoform of SRF, SRFΔ5, may play an important regulatory role in modulating SRF-dependent gene expression.
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Gerosa, Laura, Barbara Grillo, Chiara Forastieri, Alessandra Longaretti, Emanuela Toffolo, Alessandra Mallei, Silvia Bassani, Maurizio Popoli, Elena Battaglioli, and Francesco Rusconi. "SRF and SRFΔ5 Splicing Isoform Recruit Corepressor LSD1/KDM1A Modifying Structural Neuroplasticity and Environmental Stress Response." Molecular Neurobiology 57, no. 1 (July 30, 2019): 393–407. http://dx.doi.org/10.1007/s12035-019-01720-8.

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Riana, Eri. "Penerapan Sensor Ultrasonic SRF05 Berbasis Mikrocontroller ATMega 8535 Untuk Sistem Pengereman Otomatis." Journal of Information System Research (JOSH) 2, no. 4 (July 25, 2021): 268–75. http://dx.doi.org/10.47065/josh.v2i4.761.

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Transportation technology using electric energy is growing. Electric cars are increasingly being used to reduce fuel oil usage. In addition to the increasingly sophisticated performance of electric cars, the vehicle safety system must also be improved. The existence of Artificial Intelligence is one of the developments in technological sophistication in a world that is increasingly unstoppable and unavoidable. One of the most popular luxury cars in Indonesia, one of which is the Tesla, which is a sophisticated car with the support of an artificial intelligence system, making Tesla an electric car with an automatic control vehicle feature that can run without using a human driver and can provide safety protection for the driver by using automatic braking system in case of an unexpected accident. This journal proposes a future concept design for the forerunner of automatic braking for electric cars using the ATMEGA 8535 microcontroller as the main automatic control and ultrasonic distance sensor. The PWM signal from the microcontroller is used to adjust the speed of the DC motor as the main driving force of the vehicle. The display of the distance between the vehicle and the obstacle can be seen on the LCD and the buzzer is used as an indicator of the safe distance of the car. The experiment was carried out using an RC car with the area to be protected> 500cm (5m), if the SRF05 ultrasonic sensor detects an obstacle at that distance, the SRF05 ultrasonic sensor will send a signal to the microcontroller and turn on an alarm in the form of a buzzer so that the SRF05 ultrasonic sensor will stop signal propagation.
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Putri Husain, Nursuci, Herlinah B, Mithahul Khairah, and M. Akbar. "Rancang Bangun Pendeteksi Jarak Aman Mata Dengan Layar Monitor Televisi Berbasis Arduino Uno." Jurnal Teknologi dan Komputer (JTEK) 2, no. 02 (December 31, 2022): 184–89. http://dx.doi.org/10.56923/jtek.v2i02.96.

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Mata adalah indera penglihatan yang berfungsi mempersepsikan bentuk, ukuran, maupun kedudukan suatu objek. Menonton layar televisi dengan jarak 0–119 cm, dapat menyebabkan kerusakan pada mata seperti mata minus, mata juling dan penyempitan pembuluh darah. Paparan dari cahaya televisi akibat menonton terlalu dekat akan berefek pada mata seperti sakit kepala, mata rabun, mata perih, mata kering dan mata berair. Tujuan penelitian merancang bangun pendeteksi jarak aman mata dengan layar monitor televisi berbasis arduino uno guna mencegah menonton layar televisi terlalu dekat yang mengakibatkan kerusakan pada mata. Metode penelitian Research and Development berfungsi menghasilkan, mengembangkan produk tertentu serta menguji keefektifan produk (alat pendeteksi jarak aman mata). Pengujian sistem yang dilakukan adalah pengujian arduino uno, sensor HY-SRF05, LCD, push button, relay, buzzer. Hasil pengujian alat menggunakan arduino uno terdiri dari dua proses yaitu input proses dan output proses, ketika sensor HY-SRF05 mendeteksi jarak objek mata <120 cm maka relay akan memutuskan tegangan terminal selama 10 detik dan televisi OFF, sebaliknya jika jarak objek mata ≥120 cm relay akan meyambungkan tegangan ke terminal dan televisi ON. Kesimpulan sensor pendeteksi objek pada alat pengatur jarak aman mata beroperasi dengan lancar dan akurat.
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Lonteng, Imanuel Yosua, Gunawan Gunawan, and Isa Rosita. "Rancang Bangun Simulasi Alat Pendeteksi Jarak Aman Antar Kendaraan Menggunakan Sensor Ultrasonik Berbasis Arduino." JEECOM: Journal of Electrical Engineering and Computer 2, no. 2 (October 31, 2020): 22–25. http://dx.doi.org/10.33650/jeecom.v2i2.1482.

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Padatnya kendaraan di Indonesia dan semakin banyak nya variasi kendaraan akan cukup menyulitkan pengemudi, terutama pengemudi pemula untuk dapat menjaga jarak secara maksimal oleh karena panjang bumper mobil dari tiap-tiap kendaraan yang cukup bervariasi.Penelitian kali ini diharapkan kedepannya dapat membantu pengemudi untuk dapat menjaga jarak dengan kendaraan didepan, dan mengurangi resiko kecelakaan. Pada penelitian ini penulis mensimulasikan menggunakan mobil simulasi (remote control) dihubungkan dengan sensor ultrasonik HY-SRF05 yang digunakan untuk mendeteksi dan menghitung jarak terhadap objek, lalu hasil jarak tersebut di proses oleh Arduino nano yang selanjutnya apabila kondisi pertama terpenuhi mobil simulasi akan melakukan pengereman, lalu apabila kondisi kedua terpenuhi mobil simulasi akan berhentiMobil simulasi dapat berhenti sesuai dengan jarak yang diharapkan pada simulasi ini. Setelah diamati sensor akan semakin akurat apabila sudut objek penghalang terhadap sensor semakin tegak luru.
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Hanifadinna, Hanifadinna. "Perancangan Water Level Monitoring pada Raw Water Tank dengan Sensor Ultrasonik Berbasis Nodemcu di Sungai Kupang Mill." JURNAL VOKASI TEKNOLOGI INDUSTRI (JVTI) 4, no. 2 (October 31, 2022): 01–08. http://dx.doi.org/10.36870/jvti.v4i2.304.

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Kegiatan monitoring atau pengecekan pada raw water tank di pabrik kelapa sawit Sungai Kupang dilakukan dengan mengandalkan bandul ukur level dan sirine indikator. Kedua alat ini sering mengalami masalah sehingga menjadi kendala dalam kegiatan monitoring. Berdasarkan masalah tersebut maka dibuatlah alat tambahan untuk kegiatan monitoring level air dengan mengandalkan internet sebagai media penghubungnya atau disebut Internet of Things. Bertujuan untuk memudahkan kegiatan monitoring dengan akses secara jarak jauh dan dapat mengirimkan pemberitahuan level rendah pada smartphone penggunanya. Alat ini memanfaatkan konsep pengukuran yaitu suatu kegiatan membandingkan antara besaran dengan besaran acuan dimana tersusun dari beberapa komponen yaitu sensor ultrasonik HY-SRF05 sebagai pendeteksi ketinggian permukaan air, NodeMCU Esp8266 sebagai pemroses data, aplikasi Blynk dan LCD Keypad sebagai penampil data, module datalogger sebagai penyimpan data, serta komponen power supply. Data diperoleh dengan menggunakan metode kuantitatif dan kualitatif untuk mengetahui data yang berupa nominal atau berupa deskripsi. Hasil pengujian alat didapatkan error minimal 0,03% dan maksimal 3,89% dengan interval selisih 0,14 – 8,63 cm. Alat ini dapat memudahkan operator dalam melakukan monitoring level air pada raw water tank dengan akses jarak jauh dan dapat mengirimkan pemberitahuan level rendah serta dapat digunakan sebagai alternatif kegiatan monitoring selain mengandalkan alat yang telah terpasang sebelumnya.
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Mahendra, Andre, and Nini Firmawati. "Rancang Bangun Alat Mosquito Killer Menggunakan Buzzer dan Perangkap Lampu Violet." Jurnal Fisika Unand 12, no. 1 (December 25, 2022): 70–76. http://dx.doi.org/10.25077/jfu.12.1.70-76.2023.

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Telah dihasilkan alat mosquito killer menggunakan buzzer dan perangkap lampu violet. Alat mosquito killer bertujuan untuk membasmi nyamuk dengan gelombang ultrasonik. Penelitian ini membuat alat mosquito killer berbentuk tabung berdimensi (7 x 41) cm, bagian atas tabung berisikan LED violet untuk memikat nyamuk mendekati tabung, kemudian kipas 12 volt pada bagian tengah tabung untuk menghisap nyamuk ke dalam tabung. Bagian bawah tabung terdapat jaring halus sebagai keluarnya aliran udara dan tempat nyamuk terperangkap. Sensor ultrasonik SRF05 mendeteksi objek yang masuk ke dalam tabung, secara otomatis buzzer sebagai aktuator menghasilkan suara berupa gelombang ultrasonik selama 20 detik pada setiap variasi frekuensi. Objek penelitian ini adalah nyamuk, ketika nyamuk masuk ke dalam mosquito killer berjumlah 25 ekor didapatkan hasil percobaan sebagai berikut: pada frekuensi (30 – 40) kHz nyamuk yang mati adalah 0%, pada frekuensi 45 kHz nyamuk yang mati adalah 20%, pada frekuensi 50 kHz nyamuk yang mati adalah 100%, pada frekuensi 55 kHz nyamuk yang mati adalah 100% dan pada frekuensi 60 kHz nyamuk yang mati adalah 100%. Kesimpulan penelitian ini adalah frekuensi gelombang ultrasonik minimal dalam membunuh nyamuk adalah 50 kHz dengan lama waktu 20 detik.
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Suryantoro, Hery. "Prototype Sistem Monitoring Level Air Berbasis Labview dan Arduino Sebagai Sarana Pendukung Praktikum Instrumentasi Sistem Kendali." Indonesian Journal of Laboratory 1, no. 3 (August 13, 2019): 20. http://dx.doi.org/10.22146/ijl.v1i3.48718.

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Air adalah kebutuhan yang sangat penting, ketersediaan air tetap harus selalu ada baik di rumah tangga, perkantoran, tempat-tempat umum ataupun industri. Hal ini menyebabkan peran tangki penampung air fundamental untuk menjamin ketersediaan air. Pengukuran ketinggian air secara otomatis adalah salah satu parameter yang perlu diukur untuk mendeteksi keadaan tangki penampung yang meluap atau kosong. Salah satunya dengan membuat sensor pengukur level air yang diumpanbalikkan menggunakan pompa air. Pada penelitian ini dibuat prototipe dengan menggunakan Arduino Uno R3 dan software LabVIEW sebagai pusat pengolah data yang terintegrasi dengan sensor ultrasonic SRF05 sebagai pembaca ketinggian air. Prototipe ini dilengkapi dengan indikator kondisi air, indikator pompa air yang diatur dari Arduino. Metode yang digunakan pada penelitian ini yaitu perencanaan, pengumpulan bahan, perancangan hardware, pembuatan program Arduino dan LabView, pengujian. Pengambilan data dilakukan dengan mengubah level air dengan membuka kran secara bertahap. Berdasarkan hasil pengamatan didapatkan hasil perbandingan antara level air yang tertera pada tangki penampung air dengan level air yang tertampil pada monitoring Arduino dan LabVIEW yaitu level air penampung 22 cm hasil sistem monitoring 22,12 cm, level air 15,5 cm hasil sistem monitoring 14,47cm, level air 2,5 cm hasil sistem monitoring 2,52 cm. Rata-rata kesalahan pembacaan pengukuran level air sebesar 0,089 cm.
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Ngôn, Nguyễn Chí, Trần Thanh Tân, Văn Công Phụng, and Nguyễn Minh Cảnh. "CẢI THIỆN THIẾT BỊ HỖ TRỢ NGƯỜI KHIẾM THỊ ĐIỀU HƯỚNG DI CHUYỂN DÙNG SÓNG SIÊU ÂM." TNU Journal of Science and Technology 226, no. 11 (August 27, 2021): 292–99. http://dx.doi.org/10.34238/tnu-jst.4812.

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Thiết bị hỗ trợ người khiếm thị đi đường dùng sóng siêu âm và cảnh báo chướng ngại vật bằng tiếng Việt đã được nhóm nghiên cứu triển khai từ năm 2012. Tuy nhiên, thực tế sử dụng cho thấy thiết bị vẫn còn tình trạng cảnh báo sai, do giải thuật kiểm soát cảm biến siêu âm còn hạn chế. Nghiên cứu này tập trung cải thiện giải thuật để khắc phục tình trạng cảnh báo giả. Phần cứng của thiết bị được kế thừa lại, với vi điều khiển 89C2051, các mô-đun cảm biến siêu âm SRF05 và mô-đun cảnh báo tiếng Việt dùng chip ISD1420. Phần mềm hệ thống trên vi điều khiển được tích hợp thêm hàm bù sai số cảm biến dùng giải thuật bình phương tối thiểu Levenberg-Marquardt. Thử nghiệm cho thấy, giải thuật cải tiến có thể đo khoảng cách chướng ngại vật với tỷ lệ chính xác đạt hơn 96%, trong dãy khoảng hữu dụng từ 30 đến 90 cm. Đồng thời thực nghiệm thiết bị tại Hội người mù Thành phố Cần Thơ và Hội người mù huyện Đức Hòa, tỉnh Long An cho thấy, thiết bị đáp ứng được sự mong đợi của cộng đồng người khiếm thị, cũng như mang lại nhiều hi vọng cho họ về một sản phẩm hữu ích giá rẻ.
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Yoeseph, N. M., F. A. Purnomo, R. Hartono, and Nuryani. "Lora-based IoT sensor node for Real-time Flood Early Warning System." IOP Conference Series: Earth and Environmental Science 986, no. 1 (February 1, 2022): 012060. http://dx.doi.org/10.1088/1755-1315/986/1/012060.

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Abstract Internet of Things (IoT) using LoRa technology has been widely used in many fields. One of them is in disaster mitigation and management. This paper presents sensor nodes as part of a Flood Early Warning System using LoRa technology. The node consists of a water level sensor and a water flow meter. Water level measurements were carried out by ultrasonic sensors HY-SRF05, and the speed of water flow is measured by water flow meter YF-S201. Communication between the nodes and the gateway is done by the BsFrance Lora32u4 II v1.4 Wireless Transceiver module. Data regarding the height of the water level and speed of water flow will be measured by the sensor and sent by the LoRa device to the gateway. The gateway then forwards that data to an open-source IoT platform for analysis and visualization. Testing ultrasonic sensor readings get an accuracy of 97.06%. Waterflow sensor testing obtained 91.96% accuracy. In addition to testing the measurement accuracy, data transmission consistency is also tested against the distance between the gateway and the node. The test results show that the data can still be sent at a space between the node and the gateway below 400 m. Above 400m, the data cannot be received by the gateway anymore. Testing delay time between reading data and receiving data on the IoT platform shows the average delivery delay of 0 ms.
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Dissertations / Theses on the topic "SRFΔ5"

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GRILLO, BARBARA. "PARTNERS, TARGETS AND MODULATORS OF LSD1 IN STRESS-RESPONSE REGULATION." Doctoral thesis, Università degli Studi di Milano, 2019. http://hdl.handle.net/2434/612975.

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In mammals, different forms of stress, including psychosocial stress, can affect various aspects of human health, promoting mood and anxiety disorders. However, very little is known about the mechanisms underlying the brain physiology of stress response, hindering the development of new therapeutic strategies. We uncover a role for the transcriptional corepressor Lysine Specific Demethylase-1 (LSD1) and its dominant negative splicing isoform neuroLSD1, in the modulation of emotional behavior. In the mouse hippocampus, LSD1 and neuroLSD1 interacting with the transcription factor Serum Response Factor (SRF) and SRFΔ5 participate as molecular transducers of stress stimuli. Likewise LSD1, also SRF is modulated by an alternative splicing isoform without transactivation domain, SRFΔ5. Psychosocial stress acutely reduces the expression of neuroLSD1 through a splicing-based modulation that results in an increase in the amount of LSD1, while the relative ratio between SRF and SRFΔ5 is sensitive both to ASDS and CSDS. Furthermore, SRFΔ5 shows SUS-restricted downregulation that might contribute to shaping psychosocial stress vulnerability, through interfering with homeostatic mechanisms underlying stress resiliency. All these data suggest the involvement of the dual LSD1/neuroLSD1 and SRF/SRFΔ5 in the adaptive response to stress. Alternative splicing is a strategic biological mechanism that allows to create a set of functionally different gene products from a single gene, diversifying gene functions without an increase in the number of genes. neuroLSD1, an activity-dependent splicing isoform that differs from LSD1 for the inclusion of exon 8a, was related to important homeostatic neuronal functions impacting emotional processing. It has recently been published that MALAT1(metastasis associated lung adenocarcinoma transcript 1), a long non-coding RNA, has a crucial role in the alternative splicing mechanism of some genes through the regulation of the splicing factor SRSF1, belonging to the SR protein family. In particular MALAT1 is mainly localized at the level of the nuclear speckles, where it seems to regulate the alternative splicing through the retention of SRSF1 in these nuclear domains and the modulation of their phosphorylation state through an unknown mechanism. We already published that alternative splicing involving LSD1 is positively regulated in trans by two splicing factors NOVA1 and nSR100. In particular, nSR100 is a splicing factor belonging to the SR protein family, as SRSF1, and regulates tissue-specific alternative splicing in a manner dependent on its concentration and its phosphorylation status. We propose MALAT1 as a negative modulator of the neurospecific splicing of LSD1, in particular following ASDS the increased levels of MALAT1 lead to the sequestration of nSR100 at the level of nuclear speckles, making clear the mechanism behind the decrease of the dominant negative neuroLSD1 expression levels following stress We found that following a chronic psychosocial stress the expression levels of MALAT1 seem to be positively regulated only in resilient individuals who manage to maintain physiological expression levels of IEG in the hippocampus. Our hypothesis is that only resilient subjects are still able to modulate maladaptive stress-related transcription, thanks to the increased levels of MALAT1, bringing the system back to basal physiological conditions through the negative regulation of neuroLSD1 formation. All this suggests that MALAT1 could be considered a possible hallmark of resilience.
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Majerčík, Pavel. "Nízkonákladový snímač vzdálenosti pro mobilní robot založený na snímači SRF05." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2017. http://www.nusl.cz/ntk/nusl-317202.

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This master's thesis deals with determination of properties of the ultrasonic sensor SRF05. It is about finding factors that distort or have other negative effects in any way on the proper functionality of these sensors. First of all, it was necessary to program a chip mounted on signal processing board for correct functionality and operation of sensors. Then a few sets of measurements were done to determine the behaviour of sensors for different distances. In addition, we had to carry out many more measurements to find out the influence of temperature, light conditions, material of the sensed surface or cross-noise caused by the use of multiple sensors. In the next step, the approximate shape of the transmitted ultrasound was investigated to determine the zone of detection. The last task of this thesis was to compare the SRF05 sensors with other ultrasonic sensors from different manufacturers.
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Conference papers on the topic "SRFΔ5"

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Wickramasooriya, A., G. Hamilan, L. S. I. L. Jayawardena, W. M. D. L. W. Wijemanne, and S. R. Munasinghe. "Characteristics of Sonar Range Sensor SRF05." In 2008 4th International Conference on Information and Automation for Sustainability (ICIAFS). IEEE, 2008. http://dx.doi.org/10.1109/iciafs.2008.4783933.

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Nuryanto, Andi Widiyanto, and Auliya Burhanuddin. "Redirection concept of autonomous mobile robot HY-SRF05 sensor to reduce the number of sensors." In 2017 4th International Conference on Electrical Engineering, Computer Science and Informatics (EECSI). IEEE, 2017. http://dx.doi.org/10.1109/eecsi.2017.8239169.

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Lukaj, Valeria, Francesco Martella, Antonino Quattrocchi, Maria Fazio, Roberto Montanini, Massimo Villari, and Antonio Celesti. "Towards IoT Rejuvenation: a Study on HY-SRF05 Ultrasonic Sensor Ageing for Intelligent Street Pole Lamp Control in a Smart City." In 2022 IEEE Symposium on Computers and Communications (ISCC). IEEE, 2022. http://dx.doi.org/10.1109/iscc55528.2022.9912765.

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