Journal articles on the topic 'SREBP'
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Kober, Daniel L., Shimeng Xu, Shili Li, Bilkish Bajaj, Guosheng Liang, Daniel M. Rosenbaum, and Arun Radhakrishnan. "Identification of a degradation signal at the carboxy terminus of SREBP2: A new role for this domain in cholesterol homeostasis." Proceedings of the National Academy of Sciences 117, no. 45 (October 26, 2020): 28080–91. http://dx.doi.org/10.1073/pnas.2018578117.
Full textZhang, Lijun, Chunyan Li, Fang Wang, Shenghua Zhou, Mingjun Shangguan, Lina Xue, Bianying Zhang, et al. "Treatment with PPARαAgonist Clofibrate Inhibits the Transcription and Activation of SREBPs and Reduces Triglyceride and Cholesterol Levels in Liver of Broiler Chickens." PPAR Research 2015 (2015): 1–10. http://dx.doi.org/10.1155/2015/347245.
Full textAn, Hyun-Jin, Jung-Yeon Kim, Mi-Gyeong Gwon, Hyemin Gu, Hyun-Ju Kim, Jaechan Leem, Sung Won Youn, and Kwan-Kyu Park. "Beneficial Effects of SREBP Decoy Oligodeoxynucleotide in an Animal Model of Hyperlipidemia." International Journal of Molecular Sciences 21, no. 2 (January 15, 2020): 552. http://dx.doi.org/10.3390/ijms21020552.
Full textMahmud, Iqbal, Guimei Tian, Tarun Hutchison, Brandon Kim, and Daiqing Liao. "Abstract LB138: DAXX interacts with sterol regulatory element-binding proteins (SREBPs) to promote oncogenic lipogenesis and tumorigenesis in triple-negative breast cancer." Cancer Research 82, no. 12_Supplement (June 15, 2022): LB138. http://dx.doi.org/10.1158/1538-7445.am2022-lb138.
Full textWang, Hang, Feng Liu, Clarke F. Millette, and Daniel L. Kilpatrick. "Expression of a Novel, Sterol-Insensitive Form of Sterol Regulatory Element Binding Protein 2 (SREBP2) in Male Germ Cells Suggests Important Cell- and Stage-Specific Functions for SREBP Targets during Spermatogenesis." Molecular and Cellular Biology 22, no. 24 (December 15, 2002): 8478–90. http://dx.doi.org/10.1128/mcb.22.24.8478-8490.2002.
Full textBien, Clara M., and Peter J. Espenshade. "Sterol Regulatory Element Binding Proteins in Fungi: Hypoxic Transcription Factors Linked to Pathogenesis." Eukaryotic Cell 9, no. 3 (January 29, 2010): 352–59. http://dx.doi.org/10.1128/ec.00358-09.
Full textRIDGWAY, Neale D., and Thomas A. LAGACE. "Regulation of the CDP-choline pathway by sterol regulatory element binding proteins involves transcriptional and post-transcriptional mechanisms." Biochemical Journal 372, no. 3 (June 15, 2003): 811–19. http://dx.doi.org/10.1042/bj20030252.
Full textZoumi, Aikaterini, Shrimati Datta, Lih-Huei L. Liaw, Cristen J. Wu, Gopi Manthripragada, Timothy F. Osborne, and Vickie J. LaMorte. "Spatial Distribution and Function of Sterol Regulatory Element-Binding Protein 1a and 2 Homo- and Heterodimers by In Vivo Two-Photon Imaging and Spectroscopy Fluorescence Resonance Energy Transfer." Molecular and Cellular Biology 25, no. 8 (April 15, 2005): 2946–56. http://dx.doi.org/10.1128/mcb.25.8.2946-2956.2005.
Full textAmemiya-Kudo, Michiyo, Hitoshi Shimano, Alyssa H. Hasty, Naoya Yahagi, Tomohiro Yoshikawa, Takashi Matsuzaka, Hiroaki Okazaki, et al. "Transcriptional activities of nuclear SREBP-1a, -1c, and -2 to different target promoters of lipogenic and cholesterogenic genes." Journal of Lipid Research 43, no. 8 (August 2002): 1220–35. http://dx.doi.org/10.1194/jlr.m100417-jlr200.
Full textInoue, Noriyuki, Hitoshi Shimano, Masanori Nakakuki, Takashi Matsuzaka, Yoshimi Nakagawa, Takashi Yamamoto, Ryuichiro Sato, et al. "Lipid Synthetic Transcription Factor SREBP-1a Activates p21WAF1/CIP1, a Universal Cyclin-Dependent Kinase Inhibitor." Molecular and Cellular Biology 25, no. 20 (October 15, 2005): 8938–47. http://dx.doi.org/10.1128/mcb.25.20.8938-8947.2005.
Full textFIELD, F. Jeffrey, Ella BORN, Shubha MURTHY, and Satya N. MATHUR. "Polyunsaturated fatty acids decrease the expression of sterol regulatory element-binding protein-1 in CaCo-2 cells: effect on fatty acid synthesis and triacylglycerol transport." Biochemical Journal 368, no. 3 (December 15, 2002): 855–64. http://dx.doi.org/10.1042/bj20020731.
Full textLiu, Fang-Hong, Jie-Yun Song, Xiao-Rui Shang, Xiang-Rui Meng, Jun Ma, and Hai-Jun Wang. "The Gene-Gene Interaction of INSIG-SCAP-SREBP Pathway on the Risk of Obesity in Chinese Children." BioMed Research International 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/538564.
Full textCheng, Xiang, Jianying Li, and Deliang Guo. "SCAP/SREBPs are Central Players in Lipid Metabolism and Novel Metabolic Targets in Cancer Therapy." Current Topics in Medicinal Chemistry 18, no. 6 (June 28, 2018): 484–93. http://dx.doi.org/10.2174/1568026618666180523104541.
Full textBitter, Andreas, Andreas K. Nüssler, Wolfgang E. Thasler, Kathrin Klein, Ulrich M. Zanger, Matthias Schwab, and Oliver Burk. "Human Sterol Regulatory Element-Binding Protein 1a Contributes Significantly to Hepatic Lipogenic Gene Expression." Cellular Physiology and Biochemistry 35, no. 2 (2015): 803–15. http://dx.doi.org/10.1159/000369739.
Full textLewis, Caroline A., Beatrice Griffiths, Claudio R. Santos, Mario Pende, and Almut Schulze. "Regulation of the SREBP transcription factors by mTORC1." Biochemical Society Transactions 39, no. 2 (March 22, 2011): 495–99. http://dx.doi.org/10.1042/bst0390495.
Full textToth, Julia I., Shrimati Datta, Jyoti N. Athanikar, Leonard P. Freedman, and Timothy F. Osborne. "Selective Coactivator Interactions in Gene Activation by SREBP-1a and -1c." Molecular and Cellular Biology 24, no. 18 (September 15, 2004): 8288–300. http://dx.doi.org/10.1128/mcb.24.18.8288-8300.2004.
Full textMcPherson, Ruth, and Andre Gauthier. "Molecular regulation of SREBP function: the Insig-SCAP connection and isoform-specific modulation of lipid synthesis." Biochemistry and Cell Biology 82, no. 1 (February 1, 2004): 201–11. http://dx.doi.org/10.1139/o03-090.
Full textRingseis, Robert, Christine Rauer, Susanne Rothe, Denise K. Gessner, Lisa-Marie Schütz, Sebastian Luci, Gaiping Wen, and Klaus Eder. "Sterol Regulatory Element-Binding Proteins Are Regulators of the NIS Gene in Thyroid Cells." Molecular Endocrinology 27, no. 5 (May 1, 2013): 781–800. http://dx.doi.org/10.1210/me.2012-1269.
Full textHuber, Michael D., Paul W. Vesely, Kaustuv Datta, and Larry Gerace. "Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis." Journal of Cell Biology 203, no. 3 (November 11, 2013): 427–36. http://dx.doi.org/10.1083/jcb.201305076.
Full textDif, Nicolas, Vanessa Euthine, Estelle Gonnet, Martine Laville, Hubert Vidal, and Etienne Lefai. "Insulin activates human sterol-regulatory-element-binding protein-1c (SREBP-1c) promoter through SRE motifs." Biochemical Journal 400, no. 1 (October 27, 2006): 179–88. http://dx.doi.org/10.1042/bj20060499.
Full textDi Pardo, Alba, John Monyror, Luis Carlos Morales, Vaibhavi Kadam, Susanne Lingrell, Vittorio Maglione, Richard W. Wozniak, and Simonetta Sipione. "Mutant huntingtin interacts with the sterol regulatory element-binding proteins and impairs their nuclear import." Human Molecular Genetics 29, no. 3 (December 24, 2019): 418–31. http://dx.doi.org/10.1093/hmg/ddz298.
Full textTodd, Bridget L., Emerson V. Stewart, John S. Burg, Adam L. Hughes, and Peter J. Espenshade. "Sterol Regulatory Element Binding Protein Is a Principal Regulator of Anaerobic Gene Expression in Fission Yeast." Molecular and Cellular Biology 26, no. 7 (April 1, 2006): 2817–31. http://dx.doi.org/10.1128/mcb.26.7.2817-2831.2006.
Full textGiandomenico, Valeria, Maria Simonsson, Eva Grönroos, and Johan Ericsson. "Coactivator-Dependent Acetylation Stabilizes Members of the SREBP Family of Transcription Factors." Molecular and Cellular Biology 23, no. 7 (April 1, 2003): 2587–99. http://dx.doi.org/10.1128/mcb.23.7.2587-2599.2003.
Full textHu, Xiaoying, Bo Shi, Min Jin, Xuexi Wang, Ye Yuan, Jiaxiang Luo, and Qicun Zhou. "Molecular cloning, tissue distribution and gene expression in response to nutritional regulation of sterol regulatory element binding protein-1 from the swimming crab Portunus trituberculatus (Miers, 1876) (Decapoda, Portunidae)." Crustaceana 94, no. 2 (February 15, 2021): 235–50. http://dx.doi.org/10.1163/15685403-bja10095.
Full textFajas, Lluis, Kristina Schoonjans, Laurent Gelman, Jae B. Kim, Jamila Najib, Genevieve Martin, Jean-Charles Fruchart, Michael Briggs, Bruce M. Spiegelman, and Johan Auwerx. "Regulation of Peroxisome Proliferator-Activated Receptor γ Expression by Adipocyte Differentiation and Determination Factor 1/Sterol Regulatory Element Binding Protein 1: Implications for Adipocyte Differentiation and Metabolism." Molecular and Cellular Biology 19, no. 8 (August 1, 1999): 5495–503. http://dx.doi.org/10.1128/mcb.19.8.5495.
Full textLecomte, Virginie, Emmanuelle Meugnier, Vanessa Euthine, Christine Durand, Damien Freyssenet, Georges Nemoz, Sophie Rome, Hubert Vidal, and Etienne Lefai. "A New Role for Sterol Regulatory Element Binding Protein 1 Transcription Factors in the Regulation of Muscle Mass and Muscle Cell Differentiation." Molecular and Cellular Biology 30, no. 5 (December 22, 2009): 1182–98. http://dx.doi.org/10.1128/mcb.00690-09.
Full textBensinger, Steven, Yoko Kidani, M. Benjamin Hock, Joseph Argus, Evangelia Komisopoulou, and Thomas Graeber. "An essential role for SREBP signaling in T cell blastogenesis (47.17)." Journal of Immunology 188, no. 1_Supplement (May 1, 2012): 47.17. http://dx.doi.org/10.4049/jimmunol.188.supp.47.17.
Full textZHANG, Chengkang, Dong-Ju SHIN, and Timothy F. OSBORNE. "A simple promoter containing two Sp1 sites controls the expression of sterol-regulatory-element-binding protein 1a (SREBP-1a)." Biochemical Journal 386, no. 1 (February 8, 2005): 161–68. http://dx.doi.org/10.1042/bj20041514.
Full textWilentz, Robb E., Lee A. Witters, and Ellen S. Pizer. "Lipogenic Enzymes Fatty Acid Synthase and Acetyl-Coenzyme A Carboxylase are Coexpressed with Sterol Regulatory Element Binding Protein and Ki-67 in Fetal Tissues." Pediatric and Developmental Pathology 3, no. 6 (November 2000): 525–31. http://dx.doi.org/10.1007/s100240010116.
Full textEid, Walaa, Kristin Dauner, Kevin C. Courtney, AnneMarie Gagnon, Robin J. Parks, Alexander Sorisky, and Xiaohui Zha. "mTORC1 activates SREBP-2 by suppressing cholesterol trafficking to lysosomes in mammalian cells." Proceedings of the National Academy of Sciences 114, no. 30 (July 10, 2017): 7999–8004. http://dx.doi.org/10.1073/pnas.1705304114.
Full textCamargo, Nutabi, August B. Smit, and Mark H. G. Verheijen. "SREBPs: SREBP function in glia-neuron interactions." FEBS Journal 276, no. 3 (December 24, 2008): 628–36. http://dx.doi.org/10.1111/j.1742-4658.2008.06808.x.
Full textNadeau, Kristen J., Lindsay B. Ehlers, Lina E. Aguirre, Russell L. Moore, Korinne N. Jew, Heidi K. Ortmeyer, Barbara C. Hansen, Jane E. B. Reusch, and Boris Draznin. "Exercise training and calorie restriction increase SREBP-1 expression and intramuscular triglyceride in skeletal muscle." American Journal of Physiology-Endocrinology and Metabolism 291, no. 1 (July 2006): E90—E98. http://dx.doi.org/10.1152/ajpendo.00543.2005.
Full textDamiano, Fabrizio, Simone Alemanno, Gabriele V. Gnoni, and Luisa Siculella. "Translational control of the sterol-regulatory transcription factor SREBP-1 mRNA in response to serum starvation or ER stress is mediated by an internal ribosome entry site." Biochemical Journal 429, no. 3 (July 14, 2010): 603–12. http://dx.doi.org/10.1042/bj20091827.
Full textGholkar, Ankur A., Keith Cheung, Kevin J. Williams, Yu-Chen Lo, Shadia A. Hamideh, Chelsea Nnebe, Cindy Khuu, Steven J. Bensinger, and Jorge Z. Torres. "Fatostatin Inhibits Cancer Cell Proliferation by Affecting Mitotic Microtubule Spindle Assembly and Cell Division." Journal of Biological Chemistry 291, no. 33 (July 4, 2016): 17001–8. http://dx.doi.org/10.1074/jbc.c116.737346.
Full textTiong, Tung-Yu, Pei-Wei Weng, Chun-Hua Wang, Syahru Agung Setiawan, Vijesh Kumar Yadav, Narpati Wesa Pikatan, Iat-Hang Fong, Chi-Tai Yeh, Chia-Hung Hsu, and Kuang-Tai Kuo. "Targeting the SREBP-1/Hsa-Mir-497/SCAP/FASN Oncometabolic Axis Inhibits the Cancer Stem-like and Chemoresistant Phenotype of Non-Small Cell Lung Carcinoma Cells." International Journal of Molecular Sciences 23, no. 13 (June 30, 2022): 7283. http://dx.doi.org/10.3390/ijms23137283.
Full textHorton, J. D. "Sterol regulatory element-binding proteins: transcriptional activators of lipid synthesis." Biochemical Society Transactions 30, no. 6 (November 1, 2002): 1091–95. http://dx.doi.org/10.1042/bst0301091.
Full textMustafa, Maria, Tony N. Wang, Xing Chen, Bo Gao, and Joan C. Krepinsky. "SREBP inhibition ameliorates renal injury after unilateral ureteral obstruction." American Journal of Physiology-Renal Physiology 311, no. 3 (September 1, 2016): F614—F625. http://dx.doi.org/10.1152/ajprenal.00140.2016.
Full textIvashchenko, Christine Y., Benjamin T. Bradley, Zhaohui Ao, James Leiper, Patrick Vallance, and Douglas G. Johns. "Regulation of the ADMA-DDAH system in endothelial cells: a novel mechanism for the sterol response element binding proteins, SREBP1c and -2." American Journal of Physiology-Heart and Circulatory Physiology 298, no. 1 (January 2010): H251—H258. http://dx.doi.org/10.1152/ajpheart.00195.2009.
Full textLi, Yin-Xia, Xingzi Guo, Thippeswamy Gulappa, Bindu Menon, and K. M. J. Menon. "SREBP Plays a Regulatory Role in LH/hCG Receptor mRNA Expression in Human Granulosa-Lutein Cells." Journal of Clinical Endocrinology & Metabolism 104, no. 10 (May 31, 2019): 4783–92. http://dx.doi.org/10.1210/jc.2019-00913.
Full textKidani, Yoko, Heidi Elsaesser, M. Hock, Laurent Vergnes, Kevin Williams, Joseph Argus, Beth Marbois, et al. "Towards understanding the influence of lipid metabolism on CD8 T cell biology (P1136)." Journal of Immunology 190, no. 1_Supplement (May 1, 2013): 64.15. http://dx.doi.org/10.4049/jimmunol.190.supp.64.15.
Full textYang, Shui-Bo, Tao Zhao, Li-Xiang Wu, Yi-Chuang Xu, and Xiao-Ying Tan. "Effects of dietary carbohydrate sources on lipid metabolism and SUMOylation modification in the liver tissues of yellow catfish." British Journal of Nutrition 124, no. 12 (June 30, 2020): 1241–50. http://dx.doi.org/10.1017/s0007114520002408.
Full textLee, Jae-Ho, Peter Phelan, Minsang Shin, Byung-Chul Oh, Xianlin Han, Seung-Soon Im, and Timothy F. Osborne. "SREBP-1a–stimulated lipid synthesis is required for macrophage phagocytosis downstream of TLR4-directed mTORC1." Proceedings of the National Academy of Sciences 115, no. 52 (December 10, 2018): E12228—E12234. http://dx.doi.org/10.1073/pnas.1813458115.
Full textShimano, Hitoshi. "SREBPs: physiology and pathophysiology of the SREBP family." FEBS Journal 276, no. 3 (December 24, 2008): 616–21. http://dx.doi.org/10.1111/j.1742-4658.2008.06806.x.
Full textJianhua, Li, Miao Xueqin, and Hu Jifen. "Expression and clinical significance of LXRα and SREBP-1c in placentas of preeclampsia." Open Medicine 11, no. 1 (January 1, 2016): 292–96. http://dx.doi.org/10.1515/med-2016-0057.
Full textRawson, Robert B. "Control of lipid metabolism by regulated intramembrane proteolysis of sterol regulatory element binding proteins (SREBPs)." Biochemical Society Symposia 70 (September 1, 2003): 221–31. http://dx.doi.org/10.1042/bss0700221.
Full textAthanikar, J. N., H. B. Sanchez, and T. F. Osborne. "Promoter selective transcriptional synergy mediated by sterol regulatory element binding protein and Sp1: a critical role for the Btd domain of Sp1." Molecular and Cellular Biology 17, no. 9 (September 1997): 5193–200. http://dx.doi.org/10.1128/mcb.17.9.5193.
Full textLogette, E., C. Le Jossic-Corcos, D. Masson, S. Solier, A. Sequeira-Legrand, I. Dugail, S. Lemaire-Ewing, L. Desoche, E. Solary, and L. Corcos. "Caspase-2, a Novel Lipid Sensor under the Control of Sterol Regulatory Element Binding Protein 2." Molecular and Cellular Biology 25, no. 21 (November 1, 2005): 9621–31. http://dx.doi.org/10.1128/mcb.25.21.9621-9631.2005.
Full textAi, Wandong, Ying Liu, and Timothy C. Wang. "Yin yang 1 (YY1) represseshistidine decarboxylasegene expression with SREBP-1a in part through an upstream Sp1 site." American Journal of Physiology-Gastrointestinal and Liver Physiology 290, no. 6 (June 2006): G1096—G1104. http://dx.doi.org/10.1152/ajpgi.00199.2005.
Full textSAKAI, Juro. "The SREBP pathway." Journal of Japan Atherosclerosis Society 28, no. 4-5 (2001): 97–102. http://dx.doi.org/10.5551/jat1973.28.4-5_97.
Full textYang, Jing, and M. Sharon Stack. "Lipid Regulatory Proteins as Potential Therapeutic Targets for Ovarian Cancer in Obese Women." Cancers 12, no. 11 (November 21, 2020): 3469. http://dx.doi.org/10.3390/cancers12113469.
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