Relevant bibliographies by topics / Spleen stiffness

Academic literature on the topic 'Spleen stiffness'

Author: Grafiati
Published: 10 March 2023

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Contents

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Spleen stiffness.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Spleen stiffness"

1

Ran, Hai-Tao, Xiao-Ping Ye, Yuan-Yi Zheng, Da-Zhi Zhang, Zhi-Gang Wang, Johnson Chen, David Madoff, and Jing Gao. "Spleen Stiffness and Splenoportal Venous Flow." Journal of Ultrasound in Medicine 32, no. 2 (February 2013): 221–28. http://dx.doi.org/10.7863/jum.2013.32.2.221.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Morozov, S. V., and V. А. Izranov. "Comparsion of Liver and Spleen Elastometry Features." Journal of radiology and nuclear medicine 102, no. 4 (September 15, 2021): 247–54. http://dx.doi.org/10.20862/0042-4676-2021-102-4-247-254.

Full text
Abstract:
The review presents data on the comparison of the features of liver and spleen stiffness measurements and those on the impact of various conditions on the measurement results (the type of a sensor used, food intake, number of measurements, patient position, breathing phase, etc.). Literature has been sought in the PubMed and eLibrary databases. In particular, the liver and spleen stiffness values vary differently at the height of inspiration and expiration. This is due to organ engorgement with a change in intrathoracic and intraabdominal pressures, as well as to a reduction in splenic arterial flow during exhalation. The review gives published data on liver and spleen stiffness values in healthy volunteers. The spleen is a stiffer organ than the liver. The different liver and spleen stiffness is explained by the features of blood supply (the spleen receives the most blood supply from the intensive-flow artery; the liver does from the portal vein). The reasons for increasing the stiffness of these organs in both health and disease are described. Estimation of liver stiffness can be used to diagnose cirrhosis and portal hypertension. That of spleen stiffness can help in the diagnosis of portal hypertension and in the indirect diagnosis of the presence of esophageal varices and the nature of a splenic lesion.
APA, Harvard, Vancouver, ISO, and other styles
3

Yuldashev, Rustam Z., Makhmud M. Aliev, Shoilkhom I. Shokhaydarov, and Dilnoza B. Tursunova. "Non-invasive diagnostics of extrahepatic portal hypertension in children." Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care 12, no. 1 (April 12, 2022): 41–50. http://dx.doi.org/10.17816/psaic1011.

Full text
Abstract:
BACKGROUND: The primary method for diagnosing gastroesophageal bleeding in varicose veins of the esophagus and stomach in children is fibroesophagogastroduodenoscopy. This study investigates the possibilities of 2D shear wave elastography stiffness of the spleen to determine esophageal varicose veins in children with extrahepatic portal hypertension. MATERIALS AND METHODS: A retrospective analysis of the effectiveness of the method of two-dimensional elastography by shear wave stiffness of the spleen was conducted in children with extrahepatic portal hypertension in 39 children (main group) and 11 healthy children (control group). All patients initially underwent fibroesophagogastroduodenoscopy followed by ultrasound, including 2D shear wave stiffness elastography of the spleen. Spleen stiffness was then compared with clinical symptoms, the degree of esophageal varices, and other sonographic parameters. RESULTS: According to elastography data, the spleen stiffness index in children with extrahepatic portal hypertension was 43.98 3.8 kPa, significantly higher than in the control group children (p = 0.006). Spleen stiffness measurements significantly correlated with the degree of esophageal varices in children with extrahepatic portal hypertension (r = 0.57, p = 0.0002). According to the endoscopy results in seven patients after vascular bypass surgery, esophageal varicose veins were not detected. Nevertheless, spleen stiffness in these children remained significantly higher than in the control group (27 3.9 kPa and 18 1.2 kPa, respectively, p = 0.05). CONCLUSIONS: The study results indicate that 2D stiffness shear wave elastography of the spleen effectively assesses esophageal varices in children with extrahepatic portal hypertension. This method is also convenient to monitor the reduction of varicose veins after surgical treatment and is a possible alternative to endoscopy, especially in young children.
APA, Harvard, Vancouver, ISO, and other styles
4

Hanquinet, Sylviane, Céline Habre, Méryle Laurent, Mehrak Anooshiravani, and Seema Toso. "Acoustic radiation force impulse imaging: normal values of spleen stiffness in healthy children." Pediatric Radiology 51, no. 10 (May 13, 2021): 1873–78. http://dx.doi.org/10.1007/s00247-021-05079-8.

Full text
Abstract:
Abstract Background Acoustic radiation force impulse (ARFI) imaging is a noninvasive ultrasound elastography technique for evaluating tissue stiffness. The association of liver and spleen stiffness provides additional information in the assessment of portal hypertension. The technique and normal values of spleen stiffness by point shear wave elastography (p-SWE) in pediatrics have not been well documented. Objective Our aim is to describe the feasibility and normal ARFI elastography values in the spleen for healthy children and to compare measurements in two different probe positions (the axial and sagittal planes). Materials and methods Spleen p-SWE using ARFI values were measured with a 6C1 probe in 102 healthy children (age range: 8 weeks to 17 years) divided into four age groups. An average of nine (standard deviation: two) spleen stiffness measurements were taken during free breathing in each plane (axial and sagittal). The impact of age and measurement plane in the spleen was analyzed using multivariate models. Results There was no significant difference in spleen stiffness values taken at different ages, with an average of the medians of 2.43±0.31 m/s. There was no significant difference based on probe orientation: sagittal plane (median: 2.46±0.29 m/s) and axial plane (median: 2.43±0.32 m/s) with Student’s t-test P=0.18. The mean depth of measurement varied between 2.3 cm and 3.7 cm, according to age. Conclusion Normal spleen stiffness values using ARFI imaging in children do not vary with age and correspond to a median of 2.43 m/s. No significant difference was found when using different probe positions.
APA, Harvard, Vancouver, ISO, and other styles
5

Abraldes, Juan G., Enric Reverter, and Annalisa Berzigotti. "Spleen stiffness: Toward a noninvasive portal sphygmomanometer?" Hepatology 57, no. 3 (February 12, 2013): 1278–80. http://dx.doi.org/10.1002/hep.26239.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Auteri, Giuseppe, Vito Sansone, Daniela Bartoletti, Christian Di Pietro, Emanuele Sutto, Camilla Mazzoni, Nicola Vianelli, Michele Cavo, Fabio Piscaglia, and Francesca Palandri. "Spleen and Liver Fibrosis Is Associated to Treatment Response and Prognosis in Philadelphia-Negative Chronic Myeloproliferative Neoplasms." Blood 138, Supplement 1 (November 5, 2021): 3626. http://dx.doi.org/10.1182/blood-2021-152866.

Full text
Abstract:
Abstract Introduction: Spleen and liver stiffness, investigated by transient elastography (TE), have been associated with marrow fibrosis in patients (pts) with Ph-negative myeloproliferative neoplasms (MPNs) (Iurlo et al, Br J Haematol. 2015; Webb et al, Ultrasound Q. 2015). Morover, spleen stiffness was found to be greater in Myelofibrosis (MF) and Polycythemia Vera (PV) compared to Essential Thrombocythemia (ET) (Benedetti et al, J Clin Med. 2020). Tissue stiffness can be assessed by ultrasound shear wave elastography (SWE), the two most common techniques being point SWE (pSWE) and bidimensional SWE (2D.SWE). Aims: The aims of this study are: 1) to identify TE differences between MPN pts and healthy volunteers (HV); 2) to evaluate specific TE features in pts with MF, PV and ET; 3) to assess whether spleen/liver stiffness may identify clinical-laboratory features associated with prognosis in MPNs Methods: In this monocentric study, MPN pts and HV received elastometric evaluation of spleen and liver stiffness by pSWE and 2D.SWE with an Esaote MyLab™9 ultrasound system. Spleen area, portal (PVD) and splenic vein diameter (SVD) were measured. Results: A total of 220 pts were included in this study: 142 (64.5%) MPN and 78 (35.5%) HV. MPN pts were affected by MF (63, 44.4%: 39 primary MF), PV (33, 23.2%) or ET (46, 32.4%). Compared to HV, MPN pts had greater median spleen maximal cross sectional area (79 vs 38 cm2, p<0.001), greater spleen stiffness (pSWE 31.3 vs 23.7 kPa, p<0.001; 2D.SWE 25.2 vs 18.7 kPa, p<0.001), and greater liver stiffness (pSWE 6.0 vs 4.9 kPa, p<0.001; 2D.SWE 5.4 vs 4.7 kPa, p<0.001). Additionally, PVD and SVD were significantly larger in MPNs than in HV (PVD 10.9 vs 9.2 mm, p<0.001; SVD 8 vs 6.3 mm, p<0.001). Comparing each MPN to HV, only MF retained all the significant differences; conversely, liver stiffness and PVD were comparable between ET/PV and HV. Clinical and laboratory features of MPN pts are shown in Tab 1. Compared to PV and ET pts, MF pts had higher spleen (p<0.001) and liver stiffness (p<0.001), larger PVD (p<0.001) and SVD (p<0.001). Conversely, ET and PV displayed comparable TE values. Notably, higher median spleen area (p<0.001), larger SVD (p=0.03) and PVD (p=0.02), higher liver (pSWE/2D.SWE, p<0.001/p=0.002) and spleen stiffness (pSWE/2D.SWE, p=0.01/p=0.001) were associated with increased marrow fibrosis grade. Grade 0-1 marrow fibrosis was present in 15 MF, 17 PV and 34 ET pts. Considering only these 66 MPN pts, spleen (40.8 vs 31.3/25.6 in PV/ET, p=0.006) and liver (6.5 vs 5.6/4.7 in PV/ET, p=0.01) stiffness was significantly higher in MF pts. Notably, increased spleen fibrosis was significantly associated with thrombotic history (32.2 vs 24.3 kPa in pts without previous thrombosis, p=0.02). Also, MPN pts with splanchnic vein thrombosis had higher spleen (pSWE: p<0.001; 2D.SWE: p<0.001) and liver stiffness (pSWE: p <0.001), and increased PVD (p=0.02) and spleen area (p=0003). In MF pts, TE data did not correlate with DIPSS risk category. However, a higher spleen stiffness (pSWE/2D.SWE, p=0.09/ p=0.03), liver stiffness (pSWE/2D.SWE, p=0.001/p=0.01), PVD (p=0.002), and SVD (p=0.01) were associated with larger spleen length by palpation. Also, a reduced SVD was associated with the presence of ≥1 high molecular risk mutation (HMR) (p=0.04). As expected, MF pts treated with JAK-inhibitors showed larger spleen area (143.8 vs 83.7 cm 2, p=0.01) and higher spleen stiffness (34.3 vs 24 kPa, p=0.01) compared to pts under cytoreductive therapy. However, pts in spleen response at the time of TE had lower median SVD/PVD (p=0.05/p=0.07) and reduced spleen stiffness (sSWE/2D.SWE: 31.5/25.9 vs 39.0/32.8 in non-responders, p=0.01/p=0.04) In ET/PV, TE data were comparable in pts with/without a complete hematological response. However, IFN was associated with enlarged spleen area and stiffness compared to cytoreduction. Conclusions: TE evaluation effectively distinguishes MF pts from HV and ET/PV, while ET/PV show relevant similarities to each other and to HV. TE data were significantly associated with prognostically relevant features including marrow fibrosis and history of thrombosis in all MPNs, and presence of large splenomegaly and HMR in MF. Finally, TE data were significantly associated with spleen response in MF. Overall, spleen/liver stiffness may help in correct MPN diagnosis, and may provide clinical guidance, being associated with known prognostic factors and treatment outcome. Figure 1 Figure 1. Disclosures Cavo: Bristol-Myers Squib: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Adaptive Biotechnologies: Consultancy, Honoraria; Takeda: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Amgen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; GlaxoSmithKline: Consultancy, Honoraria; AbbVie: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees; Janssen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: TRAVEL, ACCOMMODATIONS, EXPENSES, Speakers Bureau; Sanofi: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Novartis: Honoraria; Celgene: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: Travel Accommodations, Speakers Bureau. Piscaglia: ESAOTE: Research Funding. Palandri: CTI: Consultancy; AOP: Membership on an entity's Board of Directors or advisory committees; Celgene: Membership on an entity's Board of Directors or advisory committees; Novartis: Membership on an entity's Board of Directors or advisory committees; Sierra Oncology: Membership on an entity's Board of Directors or advisory committees.
APA, Harvard, Vancouver, ISO, and other styles
7

Cho, Young Seo, Sanghyeok Lim, Yongsoo Kim, Joo Hyun Sohn, and Jae Yoon Jeong. "Spleen Stiffness Measurement Using 2-Dimensional Shear Wave Elastography: The Predictors of Measurability and the Normal Spleen Stiffness Value." Journal of Ultrasound in Medicine 38, no. 2 (July 23, 2018): 423–31. http://dx.doi.org/10.1002/jum.14708.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Fofiu, Renata, Felix Bende, Raluca Lupuşoru, Roxana Şirli, Alina Popescu, and Ioan Sporea. "Spleen Stiffness for Predicting Varices Needing Treatment: Comparison between Two Different Elastography Techniques (Point vs. 2D-SWE)." Canadian Journal of Gastroenterology and Hepatology 2021 (March 26, 2021): 1–9. http://dx.doi.org/10.1155/2021/6622726.

Full text
Abstract:
The study aimed to establish the benefits of using spleen stiffness values measured by two elastography techniques as noninvasive markers for predicting varices needing treatment and comparing their performances. A prospective study was performed, including 107 subjects with compensated liver cirrhosis, who underwent upper digestive endoscopy, as well as spleen stiffness measurements by means of two elastography techniques: pSWE (point shear wave elastography using Virtual Touch Quantification-Siemens Acuson S2000) and 2D-SWE (2D-shear wave elastography-LOGIQ E9, General Electric). Reliable spleen stiffness measurements were obtained in 96.2% (103/107) patients by means of 2D-SWE and in 94.4% (101/107) subjects with pSWE; therefore, 98 subjects were included in the final analysis, of which 40.8% (40/98) had varices needing treatment. The optimal spleen stiffness cut-off value by 2D-SWE for predicting varices needing treatment was 13.2 kPa (AUROC 0.84), while for pSWE, it was 2.91 m/s (AUROC 0.90). Based on AUROC comparison, no difference between the performance of the two techniques for predicting varices needing treatment was found ( p = 0.1606 ). In conclusion, spleen stiffness measured by either 2D-SWE or pSWE is a reliable surrogate marker, with good feasibility, applicability, and predictive accuracy for varices needing treatment, with no significant difference between techniques.
APA, Harvard, Vancouver, ISO, and other styles
9

Sagar Tiwari, Pratap, and Sudhamshu KC. "Spleen Stiffness Measurement as Non-Invasive Surrogate for Esophageal Varices in Chronic Liver Disease." Journal of Nobel Medical College 11, no. 1 (June 29, 2022): 27–33. http://dx.doi.org/10.3126/jonmc.v11i1.45733.

Full text
Abstract:
Background: In patients with chronic liver diseases, liver and spleen stiffness measurement by elastography is the most recent available noninvasive tool. However, the accuracy for prediction of esophageal varices has been inconsistent across various studies. So, this study was done to evaluate the diagnostic performance of spleen stiffness measurement for detecting esophageal varices. Materials and Methods: This descriptive cross-sectional study was done from 19 March to 30 June 2019. Participants who met inclusion and exclusion criteria were consecutively enrolled for the study and underwent upper gastrointestinal endoscopic examination along with measurement of liver and spleen stiffness by fibroscan. Results: A total of 78 patients were enrolled. Mean age (±SD) was 49.79 (±10.92) years. Of 78 patients, 58 (74.4 %) had esophageal varices. Among patients with varices, Small esophageal varices were present in 44.8 % (26) and large esophageal varices were present in 55.2 % (32).Liver stiffness higher than 21.7 kPa was found to detect patients with large esophageal varices and the area under the receiver operating curve being 0.79 (95% confidence interval: 0.69 – 0.89); p<0.001. It had sensitivity of 100.0% and specificity of 63% in predicting the presence of large esophageal varices. While, spleen stiffness having a cutoff value of 40 kPa with the area under the receiver operating curve being 0.98 (95% confidence interval: 0.96 – 1.00); p<0.001, had sensitivity of 100.0 % and specificity of 87.0 % in predicting the presence of large esophageal varices. Conclusion: Spleen stiffness measurements by Transient Elastography predict large esophageal varices better than liver stiffness measurements.
APA, Harvard, Vancouver, ISO, and other styles
10

Pawluś, Aleksander, Marcin S. Inglot, Kinga Szymańska, Krzysztof Kaczorowski, Bartosz D. Markiewicz, Agnieszka Kaczorowska, Jacek Gąsiorowski, et al. "Shear wave elastography of the spleen: evaluation of spleen stiffness in healthy volunteers." Abdominal Radiology 41, no. 11 (July 7, 2016): 2169–74. http://dx.doi.org/10.1007/s00261-016-0834-4.

Full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "Spleen stiffness"

1

Borghi, Alberto <1981&gt. "Portal hypertension: a comparison between portal-venous pressure measurement and ARFI measurement of liver and spleen stiffness." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2012. http://amsdottorato.unibo.it/4721/1/Tesi_Alberto_Borghi.pdf.

Full text
Abstract:
PURPOSE. Portal pressure is measured invasively as Hepatic Venous Pressure Gradient (HVPG) in the angiography room. Liver stiffness measured by Fibroscan was shown to correlate with HVPG values below 12 mmHg. This is not surprising, since in cirrhosis the increase of portal pressure is not directly linked with liver fibrosis and consequently to liver stiffness. We hypothesized that, given the spleen’s privileged location upstream to the whole portal system, splenic stiffness could provide relevant information about portal pressure. Aim of the study was to assess the relationship between liver and spleen stiffness measured by Virtual Touch™ (ARFI) and HVPG in cirrhotic patients. METHODS. 40 consecutive patients (30 males, mean age 62y, mean BMI=26, mean Child-Pugh A6, mean platelet count=92.000/mmc, 19 HCV+, 7 with ascites) underwent to ARFI stiffness measurement (10 valid measurements in right liver lobe both surface and centre, left lobe and 20 in the spleen) and HPVG, blindly to each other. Median ARFI values of 10 samplings on every liver area and of 20 samplings on spleen were calculated. RESULTS. Stiffness could be easily measured in all patients with ARFI, resulting a mean of 2,61±0,76, 2,5±0,62 and 2,55±0,66 m/sec in the liver areas and 3.3±0,5 m/s in the spleen. Median HPVG was 14 mmHg (range 5-27); 28 patients showed values ≥10 mmHg. A positive significant correlation was found between spleen stiffness and HPVG values (r=0.744, p<0.001). No significant correlation was found between all liver stiffness and HVPG (p>0,05). AUROC was calculated to test spleen stiffness ability in discriminating patients with HVPG ≥10. AUROC = 0.911 was obtained, with sensitivity of 69% and specificity of 91% at a cut-off of 3.26 m/s. CONCLUSION. Spleen stiffness measurement with ARFI correlates with HVPG in patients with cirrhosis, with a potential of identifying patients with clinically significant portal hypertension.
APA, Harvard, Vancouver, ISO, and other styles
2

Borghi, Alberto <1981&gt. "Portal hypertension: a comparison between portal-venous pressure measurement and ARFI measurement of liver and spleen stiffness." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2012. http://amsdottorato.unibo.it/4721/.

Full text
Abstract:
PURPOSE. Portal pressure is measured invasively as Hepatic Venous Pressure Gradient (HVPG) in the angiography room. Liver stiffness measured by Fibroscan was shown to correlate with HVPG values below 12 mmHg. This is not surprising, since in cirrhosis the increase of portal pressure is not directly linked with liver fibrosis and consequently to liver stiffness. We hypothesized that, given the spleen’s privileged location upstream to the whole portal system, splenic stiffness could provide relevant information about portal pressure. Aim of the study was to assess the relationship between liver and spleen stiffness measured by Virtual Touch™ (ARFI) and HVPG in cirrhotic patients. METHODS. 40 consecutive patients (30 males, mean age 62y, mean BMI=26, mean Child-Pugh A6, mean platelet count=92.000/mmc, 19 HCV+, 7 with ascites) underwent to ARFI stiffness measurement (10 valid measurements in right liver lobe both surface and centre, left lobe and 20 in the spleen) and HPVG, blindly to each other. Median ARFI values of 10 samplings on every liver area and of 20 samplings on spleen were calculated. RESULTS. Stiffness could be easily measured in all patients with ARFI, resulting a mean of 2,61±0,76, 2,5±0,62 and 2,55±0,66 m/sec in the liver areas and 3.3±0,5 m/s in the spleen. Median HPVG was 14 mmHg (range 5-27); 28 patients showed values ≥10 mmHg. A positive significant correlation was found between spleen stiffness and HPVG values (r=0.744, p<0.001). No significant correlation was found between all liver stiffness and HVPG (p>0,05). AUROC was calculated to test spleen stiffness ability in discriminating patients with HVPG ≥10. AUROC = 0.911 was obtained, with sensitivity of 69% and specificity of 91% at a cut-off of 3.26 m/s. CONCLUSION. Spleen stiffness measurement with ARFI correlates with HVPG in patients with cirrhosis, with a potential of identifying patients with clinically significant portal hypertension.
APA, Harvard, Vancouver, ISO, and other styles
3

Adriaenssens, Sigrid Maria Louis. "Stressed spline structures." Thesis, University of Bath, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.341171.

Full text
Abstract:
This thesis concerns stressed spline structures. A spline is defined as `an initially straight member with identical second moment of area about any axis perpendicular to its centroidal axis, bent into a spatial curve'. An analytical proof is presented to show that the spline's torsional stiffness is of no importance in its analysis (provided construction details do not introduce any torsional moment). This paramount proof allows the formulation of a spline analysis that relies solely on three translational degrees of freedom (3DOF) per node. Applying this 3DOF analysis to unstrained curves and battened or hoop supported membranes is approximate since the bending stiffness would correspond to one direction only. A series of four test cases validates the proposed 3DOF analysis. The analysis is first applied to a laterally loaded spline ring, where solution convergence and the effect of unequal length segment modelling are investigated. Most significantly, this test case demonstrates that the spline ring has a greater out-of-plane stiffness than a pre-bent ring. This feature lies at the basis of spline stressed membranes - the spline has superior out-of-plane stiffness under the action of forces applied by the membrane. The second and third test cases -- buckling of elastica and of a shallow sinusoidal arch -- clearly demonstrate that the 3DOF analysis is much faster, more accurate, and produces results closer to the analytical values compared with a 6DOF analysis. The fourth test case proves the efficiency of the 3DOF analysis through investigating buckling behaviour and loads of four circular arches under radial loading. As the torsional stiffness does not enter the 3DOF analysis, the stiffness of a spline constructed of spliced segments is identical to that of a continuous spline. In order to demonstrate their feasibility, five medium span (161n-32m) Glass Fibre Reinforced Plastic (GFRP) and one large span (57nt) steel tensegrity stressed spline membranes are designed, form-found and analysed under realistic loading conditions. These design studies show firstly that the spline and membrane stresses occurring under loading are within acceptable material limits and secondly that buckling occurs at values much higher than those encountered in reality. This thesis has demonstrated that engineered stressed spline structures, for which the development of a 3DOF was essential, have great design potential.
APA, Harvard, Vancouver, ISO, and other styles
4

Cheng, Yi-Wen, and 鄭翊彣. "Feasibility of Measuring Spleen Stiffness with MR Elastography and Spleen Volume to Predict the Hepatic Fibrosis Stage." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/993b83.

Full text
Abstract:
碩士
國立陽明大學
生物醫學影像暨放射科學系
104
The liver diseases deeply affect people’s health and lifespan. Generally considered that the evolutionary processes of liver diseases are as below: liver hepatitis, liver fibrosis, liver cirrhosis and finally is hepatic carcinoma. Liver cirrhosis is progressively evolved from liver fibrosis. In this process, there will be many complications, such as portal hypertension, esophageal varices, splenomegaly and ascites. Massive reports showed that spleen stiffness will increase with the portal hypertension degree and the severity of esophageal varices, and that spleen volume has positive correlation with liver fibrosis. For assessing liver fibrosis stages, liver biopsy is the gold standard. However, it is invasive, and it contains unavoidable risks and limits. As a result, we expect to find a noninvasive method to assess liver fibrosis stages. Magnetic resonance elastography (MRE) is a noninvasive imaging technique that can quantitatively measure the soft tissue’s stiffness value. This study retrospectively enrolled 109 subjects, who underwent routine abdominal MRI and MRE. All of them underwent pathological examinations 90 days before or after MRI study. We measured the spleen stiffness and the liver stiffness from MRE images, and the spleen volume from MRI images. The relationships between the spleen volume, the spleen stiffness and the liver fibrosis stages were analyzed. We also investigated the impact on the position of passive driver to the spleen stiffness values. Compared the diagnostic accuracy for advanced fibrosis (F3~F4) between the spleen stiffness, the spleen volume and the liver stiffness. In our study, the spleen volume and the spleen stiffness are both positive linear correlated with liver fibrosis stage. The spleen volume and the spleen stiffness both can be used for staging liver fibrosis, but the spleen stiffness has better performance. In conclusion, the spleen stiffness measured by MRE is a better predictor for staging liver fibrosis. If we want to measure the spleen stiffness, it is more suitable to put the passive driver on patient’s left chest wall. For discriminating advanced liver fibrosis, the accuracy of the spleen stiffness is better than the spleen volume, even as good as the liver stiffness. If we combine the liver stiffness and the spleen stiffness to discriminate the advanced liver fibrosis, the performance is the best.
APA, Harvard, Vancouver, ISO, and other styles
5

ROSSELLI, MATTEO. "Prospective evaluation of liver and spleen stiffness by transient and point shear wave elastography: surrogate markers of fibrosis and clinically significant portal hypertension in cirrhosis." Doctoral thesis, 2017. http://hdl.handle.net/2158/1078164.

Full text
Abstract:
Non-invasive assessment of liver disease has become a sub-speciality able to predict with high accuracy the presence and the severity of liver disease. The objective of this work was to evaluate the accuracy of point shear wave elastography in detecting fibrosis and portal hypertension as well as being able to distinguish cirrhotic from non-cirrhotic portal hypertension.
APA, Harvard, Vancouver, ISO, and other styles
6

BASSANELLI, CHIARA. "Valutazione della stiffness epato-splenica mediante Acoustic Radiation Force Impulse (ARFI) nella stadiazione delle epatopatie croniche." Doctoral thesis, 2014. http://hdl.handle.net/11573/918336.

Full text
Abstract:
La valutazione non invasiva della fibrosi epatica costituisce un tema di ampio dibattito e di grande interesse nel campo dell'epatologia clinica. L'Acoustic radiation Force Impulse (ARFI) è una metodica elastometrica che può essere effettuata utilizzato alcuni ecografi di ultima generazione. Lo scopo del lavoro è quello di valutarne la capacità di stadiazione e il valore prognostico in una popolazione di pazienti affetti da malattia epatica cronica a diversa eziologia e gravità. Sono inoltre presentati dati inerenti allo studio e al monitoraggio dell'ipertensione portale attraverso l'utilizzo dell'elastometria splenica.
APA, Harvard, Vancouver, ISO, and other styles

Book chapters on the topic "Spleen stiffness"

1

Colecchia, Antonio, Élise Vuille-Lessard, and Annalisa Berzigotti. "Spleen Stiffness." In Portal Hypertension VII, 121–33. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-08552-9_12.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Furuichi, Yoshihiro, and Fuminori Moriyasu. "Liver and Spleen Stiffness Measurement." In Clinical Investigation of Portal Hypertension, 127–35. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-10-7425-7_11.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Colecchia, Antonio, Federico Ravaioli, Giovanni Marasco, and Davide Festi. "Spleen Stiffness by Ultrasound Elastography." In Diagnostic Methods for Cirrhosis and Portal Hypertension, 113–37. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-72628-1_8.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Elshaarawy, Omar, Johannes Mueller, and Sebastian Mueller. "Spleen Stiffness to Liver Stiffness Ratio and Disease Etiology." In Liver Elastography, 369–74. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-40542-7_33.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

da Silva Tavares Veiga, Zulane, Cristiane Alves Vilella Nogueira, and Flavia Ferreira Fernandes. "Liver and Spleen Stiffness in Schistosomiasis." In Liver Elastography, 153–59. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-40542-7_12.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Giunta, Mariangela, and Mirella Fraquelli. "Liver and Spleen Stiffness in Hematological Diseases." In Elastography of the Liver and Beyond, 257–68. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-74132-7_17.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Segato, Simone. "Case 2: Liver and Spleen Stiffness After TIPS." In Elastography of the Liver and Beyond, 275–79. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-74132-7_19.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Ravaioli, Federico, Elton Dajti, Luigina V. Alemanni, and Antonio Colecchia. "Liver and Spleen Stiffness in Vascular Liver Disease." In Elastography of the Liver and Beyond, 235–55. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-74132-7_16.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Sharma, Praveen. "Liver and Spleen Stiffness in Patients with Portal Vein Thrombosis." In Liver Elastography, 177–80. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-40542-7_15.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Mendoza, Yuly P., Giuseppe Murgia, Susana G. Rodrigues, Maria G. Delgado, and Annalisa Berzigotti. "Liver and Spleen Stiffness to Predict Portal Hypertension and Its Complications." In Liver Elastography, 325–59. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-40542-7_31.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Spleen stiffness"

1

Büchter, M., A. Kahraman, A. Dechêne, P. Manka, J. Theysohn, M. Reinboldt, A. Canbay, and G. Gerken. "Spleen stiffness is positively correlated with HVPG and decreases significantly after TIPS implantation." In Viszeralmedizin 2017. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1605108.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Elshaarawy, O., S. Alquzi, V. Rausch, J. Mueller, I. Silva, T. Peccerella, HK Seitz, and S. Mueller. "Response of spleen stiffness to portal pressure lowering drugs in a rat model of cirrhosis." In 35. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0038-1677069.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Elshaarawy, O., J. Mueller, IN Guha, J. Chalmers, R. Harris, M. Thiele, BS Madsen, et al. "Spleen to liver stiffness ratio significantly differs between ALD and HCV and predicts disease-specific complications." In 35. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0038-1677122.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Roccarina, Davide, Francesca Saffioti, Matteo Rosselli, Anna Mantovani, Roberta Stupia, Aileen Marshall, Massimo Pinzani, and Douglas Thorburn. "OTU-12 Spleen stiffness has a good performance in predicting clinically significant portal hypertension in PSC." In British Society of Gastroenterology Annual Meeting, 17–20 June 2019, Abstracts. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2019. http://dx.doi.org/10.1136/gutjnl-2019-bsgabstracts.203.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Atzori, Sebastiana, Lucy Garvey, Tim Hoogenboom, James Maurice, Graham Cooke, and Simon Taylor-Robinson. "PWE-073 Spleen stiffness via acoustic radiation force impulse in HIV patients with non cirrhotic portal hypertension." In British Society of Gastroenterology, Annual General Meeting, 4–7 June 2018, Abstracts. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2018. http://dx.doi.org/10.1136/gutjnl-2018-bsgabstracts.215.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Saffioti, Francesca, Davide Roccarina, Matteo Rosselli, Roberta Stupia, Aileen Marshall, Massimo Pinzani, and Douglas Thorburn. "PTU-034 Spleen stiffness by elastPQ point shear wave elastography predicts clinically significant portal hypertension in PBC." In British Society of Gastroenterology Annual Meeting, 17–20 June 2019, Abstracts. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2019. http://dx.doi.org/10.1136/gutjnl-2019-bsgabstracts.243.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Marasco, Giovanni, Elton Dajti, Federico Ravaioli, Antonio Colecchia, Maria Letizia Bacchi Reggiani, Agostino Colli, Luigina Vanessa Alemanni, et al. "IDDF2019-ABS-0108 Hepatic decompensation risk is reduced, but not eliminated after direct-acting antivirals: the role of spleen stiffness measurement." In International Digestive Disease Forum (IDDF) 2019, Hong Kong, 8–9 June 2019. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2019. http://dx.doi.org/10.1136/gutjnl-2019-iddfabstracts.13.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Retoriano, Katherine, Shirley Christine Margarett Velasco, Odessa Bayani, and Emaluz Parian-De Los Angeles. "IDDF2022-ABS-0037 Spleen stiffness measurement by elastography in the diagnosis of portal hypertension in children: a systematic review and meta-analysis." In Abstracts of the International Digestive Disease Forum (IDDF), Hong Kong, 2–4 September 2022. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2022. http://dx.doi.org/10.1136/gutjnl-2022-iddf.90.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Hong, J., D. Talbot, and A. Kahraman. "A Stiffness Formulation for Spline Joints." In ASME 2015 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/detc2015-47336.

Full text
Abstract:
Due to the lack of knowledge in terms of their flexibility and deformation, spline joints are typically assumed to be rigid in dynamic models of gearboxes, transmissions and drive trains. As various dynamic phenomena are associated with the stiffness of a spline joint, any high-fidelity dynamic model of drivetrains must properly capture the stiffness of spline joints. In this study, a general analytical stiffness formulation for spline joints is proposed based on a semi-analytical spline load distribution model. This formulation defines a fully-populated stiffness matrix of a spline joint including radial, tilting and torsional stiffness values as well as off-diagonal coupling terms. A blockwise inversion method is proposed and implemented with this analytical formulation to reduce computational time required. At the end, a detailed parametric study is presented to demonstrate the sensitivity of the spline stiffness matrix to torque level, tooth modifications, misalignments, and tooth indexing errors.
APA, Harvard, Vancouver, ISO, and other styles
10

Wu, Fayong, Zhichao Liang, Yanhong Ma, and Dayi Zhang. "Bending Stiffness and Dynamic Characteristics of a Rotor With Spline Joints." In ASME 2013 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/imece2013-62657.

Full text
Abstract:
Spline is a kind of typical joint structures widely used in the aero-engine rotor system. The stiffness distribution of the spool is affected by the spline joint’s stiffness directly. Therefore, it is significant to investigate the spline joint’s stiffness characteristics and its influences on the dynamic characteristics of the rotor system. To figure out the factors that affect the bending stiffness of the spline joint, a mechanical model which takes contact state into account was built based on the structure analysis and force state analysis. In addition, an actual rotor with a spline joint was established to measure the stiffness under different loads, and the results were compared with the analysis by three modeling methods. Furthermore, the natural frequencies of the rotor were tested. Obtained results indicate that the structural discontinuity, the surface stiffness and the clearance fit cause the loss of local angular stiffness and linear stiffness. Meanwhile, the stiffness of the rotor with the spline joint is weaker along with the increase of the load/deformation, and become stable when undergoing the huge load/deformation. Besides, the local blending stiffness is presented as nonlinear and uncertainty subjected to an interval, which further affected the dynamic characteristics of rotor system.
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic 'Spleen stiffness' for particular source types:
Journal articles
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography