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Academic literature on the topic 'SPIO NP'

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Published: 1 April 2023

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Journal articles on the topic "SPIO NP"

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Javid, Amaneh, Shahin Ahmadian, Ali Akbar Saboury, Seyed Mehdi Kalantar, and Saeed Rezaei-Zarchi. "Novel biodegradable heparin-coated nanocomposite system for targeted drug delivery." RSC Adv. 4, no. 26 (2014): 13719–28. http://dx.doi.org/10.1039/c3ra43967d.

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HP–SPIO NPs (42 nm) were formulated by co-precipitation. Doxorubicin and paclitaxel were loaded into the SPIO NP core. HP–SPIO NPs had sustained release of DOX (87%) and PTX (75%) at pH 6.0. Drug loaded HP–SPIO NPs caused 95 and 84%, and 85 and 77% apoptosis in A2780 and OVCAR-3 cells, respectively. DOX–HP–SPIO NPs and PTX–HP–SPIO NPs caused a sharp decrease in bcl-2 and survivin proteins.
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Aleid, Adham, Khalid Alhussaini, Mohammed Almijalli, and Ali S. Saad. "Estimation of SPIO Nanoparticles Uptakes by Macrophages Using Transmission Electron Microscopy." International Journal of Molecular Sciences 23, no. 22 (November 9, 2022): 13801. http://dx.doi.org/10.3390/ijms232213801.

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Due to their interesting size-dependent magnetic characteristics and relative biocompatibility, magnetic superparamagnetic iron oxide (SPIO) nanoparticles have been widely exploited as probes for cell and subcellular structure identification, as well as medication and gene delivery. A thorough understanding of the mechanics of the interaction between nanoparticles and macrophages is vital in managing dynamic processes in nanomedicine. In this study, the interaction behavior and uptake of SPIO nanoparticles by M1- and M2-type macrophages were investigated. Mice monocytes were differentiated into M1 and M2 macrophages, and the uptake of SPIO nanoparticles was studied using a TEM microscope. A high resolution image of 1 nm resolution, an image processing technique, was developed to extract the SPIO-NPs from tomographic TEM microscopic images. Lysosomes appear to be the zones of high concentrations of SPIO inside macrophages. Lysosomes were first selected in each image, and then segmentation by the Otsu thresholding method was used to extract the SPIO-NPs. The Otsu threshold method is a global thresholding technique used to automatically differentiate SPIOs from the background. The SPIO-NPs appear in red colors, and the other pixels in the image are considered background. Then, an estimation of the SPIO-NP uptakes by lysosomes is produced. Higher uptake of all-sized nanoparticles was observed in M1- and M2-type macrophages. An accurate estimation of the number of SPIO-NPs was obtained. This result will help in controlling targeted drug delivery and assessing the safety impact of the use of SPIO-NPs in nanomedicine for humans.
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Lin, Martin Hsiu-Chu, Chiu-Yen Chung, Kuo-Tai Chen, Jih-Chao Yeh, Tsong-Hai Lee, Ming-Hsueh Lee, I.-Neng Lee, Wei-Chao Huang, and Jen-Tsung Yang. "Comparison between Polybutylcyanoacrylate Nanoparticles with Either Surface-Adsorbed or Encapsulated Brain-Derived Neurotrophic Factor on the Neural Differentiation of iPSCs." International Journal of Molecular Sciences 20, no. 1 (January 6, 2019): 182. http://dx.doi.org/10.3390/ijms20010182.

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The brain-derived neurotrophic factor (BDNF) is vital in the neural differentiation of neural stem/progenitor cells, and together may have therapeutic potential for neural regeneration. In this study, a multiplexed polybutylcyanoacrylate nanoparticle (PBCA NP) delivery platform was constructed, incorporating either surface-adsorbed or encapsulated BDNF for the induction of neural differentiation in induced pleuripotent stem cells (iPSCs), where tween 80 (T80) and superparamagnetic iron oxide (SPIO) were added for central nervous system (CNS) targeting and magnetic resonance (MR) image tracking, respectively. Both methods by which the BDNF was carried resulted in loading efficiencies greater than 95%. The nanoparticle-mediated delivery of BDNF resulted in neural differentiation of iPSCs detected on immunofluorescence staining as early as 7 days, with enhanced differentiation efficiency by 1.3-fold compared to the control on flow cytometry; the delivery system of surface-adsorbed BDNF gave rise to cells that had the best neural development than the encapsulated formulation. T80-coating disrupted the in vitro blood–brain barrier model with a corresponding 1.5- to two-fold increase in permeability. SPIO-loaded PBCA NPs exhibited a concentration-dependent, rapid decay in signal intensity on the phantom MR experiment. This study demonstrates the versatility of the PBCA NP, and the surface-adsorption of BDNF is the preferred method of delivery for the differentiation of iPSCs.
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Dong, Wei, Anqi Huang, Jixiu Huang, Pengying Wu, Shifang Guo, Huasheng Liu, Mengfan Qin, et al. "Plasmid-loadable magnetic/ultrasound-responsive nanodroplets with a SPIO-NP dispersed perfluoropentane core and lipid shell for tumor-targeted intracellular plasmid delivery." Biomaterials Science 8, no. 19 (2020): 5329–45. http://dx.doi.org/10.1039/d0bm00699h.

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McNaughton, M. W., K. Johnston, D. R. Swenson, D. Tupa, R. L. York, D. A. Ambrose, P. Coffey, et al. "np-elastic analyzing powerAN0and spin transferKNN." Physical Review C 48, no. 1 (July 1, 1993): 256–65. http://dx.doi.org/10.1103/physrevc.48.256.

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Haffter, P., C. Brogli-Gysin, J. Campbell, D. Fritschi, J. Götz, M. Hammans, R. Henneck, et al. "Spin-dependent np total cross section." Nuclear Physics A 548, no. 1 (October 1992): 29–38. http://dx.doi.org/10.1016/0375-9474(92)90074-t.

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SHARMA, S. K., and U. KHANAL. "PERTURBATION OF FRW SPACETIME IN NP FORMALISM." International Journal of Modern Physics D 23, no. 02 (January 29, 2014): 1450017. http://dx.doi.org/10.1142/s0218271814500175.

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Jacobi polynomials appear to play a very important role in describing all the spin field (s = 0, 1/2, 1, 2) perturbation of the Friedmann–Robertson–Walker (FRW) spacetime. The formulation becomes very transparent when done in Newman–Penrose (NP) formalism. All the variables are separable, and the spatial eigenfunctions turn out to be Jacobian polynomials in different forms. In particular, the angular ones are expressible as spin weighted spherical harmonics which are just the spherical harmonics formed with Jacobi polynomials. The radial eigenfunctions are also Jacobi polynomials but with unconventional parameters. Various properties of these polynomials are used to describe the scalar, vector and tensor modes of the perturbation. The Green's function of the scalar perturbations and also its Lienard–Wiechert type potentials are derived, and are shown to reduce to the familiar ones in the limit to flat FRW case. Some of the components of the perturbed metric tensor hμν have also been calculated.
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Huang, Y. W., C. K. Lo, and Y. D. Yao. "Spin-valve transistor with a NP junction." Journal of Magnetism and Magnetic Materials 304, no. 1 (September 2006): e279-e281. http://dx.doi.org/10.1016/j.jmmm.2006.02.018.

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Orus, R. "Two slightly-entangled NP-complete problems." Quantum Information and Computation 5, no. 6 (September 2005): 449–55. http://dx.doi.org/10.26421/qic5.6-3.

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We perform a mathematical analysis of the classical computational complexity of two genuine quantum-mechanical problems, which are inspired in the calculation of the expected magnetizations and the entanglement between subsystems for a quantum spin system. These problems, which we respectively call SES and SESSP, are specified in terms of pure slightly-entangled quantum states of $n$ qubits, and rigorous mathematical proofs that they belong to the NP-Complete complexity class are presented. Both SES and SESSP are, therefore, computationally equivalent to the relevant $3$-SAT problem, for which an efficient algorithm is yet to be discovered.
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AFANASJEV, A. V. "HIGH-SPIN STRUCTURES AS THE PROBES OF PROTON-NEUTRON PAIRING." International Journal of Modern Physics E 16, no. 02 (February 2007): 275–88. http://dx.doi.org/10.1142/s0218301307005715.

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Rotating N = Z nuclei in the mass A = 58-80 region have been studied within the framework of isovector mean field theory. Available data is well and systematically described in the calculations. The present study supports the presence of strong isovector np pair field at low spin, which is, however, destroyed at high spin. No clear evidence for the existence of the isoscalar t = 0 np pairing has been found.
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Dissertations / Theses on the topic "SPIO NP"

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Montalva, Medel Marco. "Problèmes type "Feedback Set" et comportement dynamique des réseaux de régulation." Phd thesis, Université de Grenoble, 2011. http://tel.archives-ouvertes.fr/tel-00629549.

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Dans la nature existent de nomreux exemples de systèmes dynamiques complexes: systèmes neuronaux, communautés, écosystèmes, réseaux de régulation génétiques, etc. Ces derniers, en particulier, sont de notre intérêt et sont souvent modélisés par des réseaux booléens. Un réseau booléenne peut être considérée comme un digraphe, où les sommets correspondent à des gènes ou de produits de gènes, tandis que les arcs indiquent les interactions entre eux. Une niveau d'expression des gènes est modélisé par des valeurs binaires, 0 ou 1, indiquant deux états de la transcription, soit activité, soit inactivité, respectivement, et ce niveau change dans le temps selon certains fonction locaux d'activation qui dépend des états d'un ensemble de nœuds (les gènes). L'effet conjoint des fonctions d'activation locale définit une fonction de transition globale: ainsi, le autre élément nécessaire dans la description du modèle est fonction de mise à jour, qui détermine quand chaque nœud doit être mis à jour, et donc, comme les fonctions local se combinent dans une fonction globale (en d'autres termes, il doit décrire les temps relative de les activités régulatoires). Comme un réseau booléen avec n sommets a 2 ^ n états globaux, à partir d'un état ​​de départ, et dans un nombre fini de mises à jour, le réseau atteindra un fixe point ou un cycle limite, appelée attracteurs qui sont souvent associées à des phénotypes distincts (états-cellulaire) définis par les patrons d'activité des gènes. Un réseau de régulation Booléenne (REBN) est un réseau Booléen où chaque interaction entre les éléments de la réseau correspond soit à une interaction positif ou d'une interaction négative. Ainsi, le digraphe interaction associée à une REBN est un digraphe signé où un circuit est appelé positif (négatif) si le nombre de ses arcs négative est pair (impair). Dans ce contexte, il y a diverses études sur l'importance du les circuits positif et négatifs dans le comportement dynamique de différents systèmes en Biologie. En effet le point de départ de cette thèse est basée sur un résultat en disant que le nombre maximal de points fixes d'une REBN dépend d'un ensemble de cardinalité minimale qu'intersecte tous les cycles positifs (également dénommés positive feedback vertex set) du digraphe signé associé. D'autre part, un autre aspect important de circuits est leur rôle dans la robustesse des réseaux booléens par rapport différents types de mise à jour déterministe. Dans ce contexte, un élément clé mathématique est le update digraphe qui est un digraphe étiqueté associé à la réseau dont les étiquettes sur les arcs sont définies comme suit: un arc (u,v) est dit être positif si l'état de sommet u est mis à jour en même temps ou après que celle de v, et négative sinon. Ainsi, un cycle dans le digraphe étiqueté est dite positive (négative) si tous ses arcs sont positifs (négatifs). Cela laisse en évidence que parler de "positif" et "négatif" a des significations différentes selon le contex: digraphes signé ou digraphes étiquetés. Ainsi, nous allons voir dans cette thèse, les relations entre les feedback sets et la dynamique des réseaux Booléens à travers l'étude analytique de ces deux fondamentaux objets mathématiques: le digraphe (de connexion) signé et l'update digraphe.
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Book chapters on the topic "SPIO NP"

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Terrien, Y., G. Bruge, P. Couvert, B. Fabbro, J. C. Faivre, C. Kerboul, M. Rouger, F. Wellers, R. Beurtey, and J. Saudinos. "Study of the np→ppπ- Reaction with the Vertex Detector Arcole." In Spin and Isospin in Nuclear Interactions, 161–66. Boston, MA: Springer US, 1991. http://dx.doi.org/10.1007/978-1-4615-3834-9_14.

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Grest, Gary S., C. M. Soukoulis, K. Levin, and R. E. Randelman. "Monte Carlo and mean field slow cooling simulations for spin glasses: relation to NP-completeness." In Heidelberg Colloquium on Glassy Dynamics, 307–24. Berlin, Heidelberg: Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/bfb0057525.

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Yi, Rongjie, Haijun Yu, Qi Zhang, Liu Yang, and Chengwu Yi. "Mechanism and Pathway of Nonylphenol Degradation in Aqueous Solution by Dielectric Barrier Discharge." In Advances in Transdisciplinary Engineering. IOS Press, 2021. http://dx.doi.org/10.3233/atde210274.

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Nonylphenol (NP) is a typical environmental endocrine disruptor with low concentration and high toxicity, μg/L level of NP is enough to interfere with the sex differentiation of many aquatic organisms and affect the population dynamic balance. The mechanism and pathway of NP degradation in aqueous solution by strong ionization dielectric barrier discharge were studied. The results showed that the degradation rate of NP can reach 95.2% in 60 min when the flow rate of O3 is 5 L/min and the input voltage is 3.8 kV. Based on the electron spin resonance (ESR) results and the detection of O3, a large amount of hydroxyl radical (·OH) and O3 were verified. In addition, the ability of DBD method to degrade NP was also tested. The intermediate products were analyzed by liquid chromatography-mass spectrometry (LC-MS), and the degradation pathway was speculated.
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Kobe, Sigismund, and Jarek Krawczyk. "Ground States, Energy Landscape, and Low-Temperature Dynamics of ± J Spin Glasses." In Computational Complexity and Statistical Physics. Oxford University Press, 2005. http://dx.doi.org/10.1093/oso/9780195177374.003.0013.

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The previous three chapters have focused on the analysis of computational problems using methods from statistical physics. This chapter largely takes the reverse approach. We turn to a problem from the physics literature, the spin glass, and use the branch-and-bound method from combinatorial optimization to analyze its energy landscape. The spin glass model is a prototype that combines questions of computational complexity from the mathematical point of view and of glassy behavior from the physical one. In general, the problem of finding the ground state, or minimal energy configuration, of such model systems belongs to the class of NP-hard tasks. The spin glass is defined using the language of the Ising model, the fundamental description of magnetism at the level of statistical mechanics. The Ising model contains a set of n spins, or binary variables si, each of which can take on the value up (si = 1) or down (si= 1).
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Conference papers on the topic "SPIO NP"

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Beddo, Michael E. "Status of NP spin-dependent total cross sections and spin-spin correlation parameters." In Intersections between particle and nuclear physics. AIP, 1992. http://dx.doi.org/10.1063/1.41543.

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Habs, D., P. G. Thirolf, C. Lang, M. Jentschel, U. Köster, F. Negoita, and V. Zamfir. "Medical applications studies at ELI-NP." In SPIE Optics + Optoelectronics, edited by Kenneth W. D. Ledingham, Wim P. Leemans, Eric Esarey, Simon M. Hooker, Klaus Spohr, and Paul McKenna. SPIE, 2011. http://dx.doi.org/10.1117/12.888986.

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Davis, C. A. "Measurements of np observables at TRIUMF." In HIGH−ENERGY SPIN PHYSICS/EIGHTH INTERNATIONAL SYMPOSIUM. AIP, 1989. http://dx.doi.org/10.1063/1.38206.

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Li, Qiao. "NP-completeness result for positive line-by-fill SADP process." In SPIE Photomask Technology, edited by M. Warren Montgomery and Wilhelm Maurer. SPIE, 2010. http://dx.doi.org/10.1117/12.864302.

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Zamfir, N. V. "Extreme Light Infrastructure-Nuclear Physics (ELI-NP): status and perspectives." In SPIE Optics + Optoelectronics, edited by Georg Korn and Luis O. Silva. SPIE, 2015. http://dx.doi.org/10.1117/12.2185185.

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Koulov, Michael A., Natalia O. Vasetskaya, and Vadim K. Ivanov. "Auto-ionizing 3s to np resonances in neutral potassium and calcium." In SPIE Proceedings, edited by Alexander I. Melker. SPIE, 2004. http://dx.doi.org/10.1117/12.555382.

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Ursescu, Daniel, Ovidiu Tesileanu, Dimiter Balabanski, Gheorghe Cata-Danil, Constantin Ivan, Ioan Ursu, Sydney Gales, and Nicolae V. Zamfir. "Extreme light infrastructure nuclear physics (ELI-NP): present status and perspectives." In SPIE Optics + Optoelectronics, edited by Joachim Hein, Georg Korn, and Luis O. Silva. SPIE, 2013. http://dx.doi.org/10.1117/12.2021776.

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Blesener, Thea, Argha Mondal, Jyothi U. Menon, Kytai T. Nguyen, and Samarendra Mohanty. "Optical tweezers based measurement of PLGA-NP interaction with prostate cancer cells." In SPIE BiOS, edited by Alexander N. Cartwright and Dan V. Nicolau. SPIE, 2013. http://dx.doi.org/10.1117/12.2008237.

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Dey, Priyanka, William Olds, Idriss Blakey, Kristofer J. Thurecht, Emad L. Izake, and Peter M. Fredericks. "SERS-barcoded colloidal gold NP assemblies as imaging agents for use in biodiagnostics." In SPIE BiOS, edited by Anita Mahadevan-Jansen and Wolfgang Petrich. SPIE, 2014. http://dx.doi.org/10.1117/12.2037159.

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Gu, Ling, Argha Mondal, Homa Homayoni, Kytai Nguyen, and Samarendra Mohanty. "Measurement of PLGA-NP interaction with single smooth muscle cells using optical tweezers." In SPIE NanoScience + Engineering, edited by Hooman Mohseni, Massoud H. Agahi, and Manijeh Razeghi. SPIE, 2012. http://dx.doi.org/10.1117/12.930588.

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Reports on the topic "SPIO NP"

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Garnett, R. W. Measurement of np elastic scattering spin-spin correlation parameters at 484, 634, and 788 MeV. Office of Scientific and Technical Information (OSTI), March 1989. http://dx.doi.org/10.2172/6207583.

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Beddo, M. E. A measurement of. Delta. sigma. sub L (np), the difference between neutron-proton total cross sections in pure longitudinal spin states. Office of Scientific and Technical Information (OSTI), October 1990. http://dx.doi.org/10.2172/6784251.

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