Academic literature on the topic 'Spatial structure stereology'

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Journal articles on the topic "Spatial structure stereology"

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Noorafshan, Ali, Saied Karbalay-Doust, Hajar Khazraei, Ali Rafati, and Hossein Mirkhani. "Spatial arrangement of the heart structure: Application of second-order stereology in diabetic rats." Annals of Anatomy - Anatomischer Anzeiger 196, no. 1 (January 2014): 20–25. http://dx.doi.org/10.1016/j.aanat.2013.04.012.

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IGARASHI, Shin-ichi, Yoshihiro YONEYAMA, and Akio WATANABE. "QUANTITATIVE EVALUATION OF SPATIAL STRUCTURE OF CONSTITUENT PHASES IN CEMENT PASTES BY SECOND-ORDER STEREOLOGY." Doboku Gakkai Ronbunshuu E 63, no. 3 (2007): 444–58. http://dx.doi.org/10.2208/jsceje.63.444.

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Kubínová, Lucie, Xiao Wen Mao, and Jiří Janáček. "Blood Capillary Length Estimation from Three-Dimensional Microscopic Data by Image Analysis and Stereology." Microscopy and Microanalysis 19, no. 4 (May 14, 2013): 898–906. http://dx.doi.org/10.1017/s1431927613001487.

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AbstractStudies of the capillary bed characterized by its length or length density are relevant in many biomedical studies. A reliable assessment of capillary length from two-dimensional (2D), thin histological sections is a rather difficult task as it requires physical cutting of such sections in randomized directions. This is often technically demanding, inefficient, or outright impossible. However, if 3D image data of the microscopic structure under investigation are available, methods of length estimation that do not require randomized physical cutting of sections may be applied. Two different rat brain regions were optically sliced by confocal microscopy and resulting 3D images processed by three types of capillary length estimation methods: (1) stereological methods based on a computer generation of isotropic uniform random virtual test probes in 3D, either in the form of spatial grids of virtual “slicer” planes or spherical probes; (2) automatic method employing a digital version of the Crofton relations using the Euler characteristic of planar sections of the binary image; and (3) interactive “tracer” method for length measurement based on a manual delineation in 3D of the axes of capillary segments. The presented methods were compared in terms of their practical applicability, efficiency, and precision.
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Dockery, P., J. Bermingham, and D. Jenkins. "Structure—function relations in the human placenta." Biochemical Society Transactions 28, no. 2 (February 1, 2000): 202–8. http://dx.doi.org/10.1042/bst0280202.

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The human haemochorial placenta is a complex and dynamic interface between embryonic and maternal tissues. A myriad array of compounds has been identified at this interface, some of which exert local effects which might be important in maintaining the integrity of the organ. These compounds are diverse in nature and function; they include enzymes, hormones and bioactive peptides. Successful nidation requires the synchronization of endometrial maturation and embryonic development. The complex nature of this interface requires the application of sound sampling strategies. The new stereological methods have thrown fresh light on the growth and development of the human placenta. These methods permit the objective, quantitative description of morphology by efficient design-based methods. This approach has permitted a better definition of the functional morphology of the placenta. Applications of these methodologies are providing a spatial and temporal framework on which to lay the new physiological and molecular information. Here we review the essential features of the stereological approach, identify useful structural quantities and provide some examples of their application. The problems associated with the quantification of immunocytochemistry are illustrated with the use of immunoreactivity to insulin-like growth factor I receptor in normal placentae and in pre-eclampsia. Although stereology can provide useful quantitative information about the structure of this dynamic tissue, other anatomical methods that could be applied to better define the relationships between structure and function will be discussed. These include confocal microscopy, to examine the dynamic physiological interactions of the different tissue compartments, and low-temperature electron microscopy techniques such as cryosubstitution, to allow better access to the biochemical information resident in the tissue. The complex and dynamic nature of the tissue requires a multidisciplinary approach; central to these investigations is a comprehensive understanding of its fine structure.
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Vasilescu, Dragoş M., Christine Klinge, Lars Knudsen, Leilei Yin, Ge Wang, Ewald R. Weibel, Matthias Ochs, and Eric A. Hoffman. "Stereological assessment of mouse lung parenchyma via nondestructive, multiscale micro-CT imaging validated by light microscopic histology." Journal of Applied Physiology 114, no. 6 (March 15, 2013): 716–24. http://dx.doi.org/10.1152/japplphysiol.00855.2012.

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Quantitative assessment of the lung microstructure using standard stereological methods such as volume fractions of tissue, alveolar surface area, or number of alveoli, are essential for understanding the state of normal and diseased lung. These measures are traditionally obtained from histological sections of the lung tissue, a process that ultimately destroys the three-dimensional (3-D) anatomy of the tissue. In comparison, a novel X-ray-based imaging method that allows nondestructive sectioning and imaging of fixed lungs at multiple resolutions can overcome this limitation. Scanning of the whole lung at high resolution and subsequent regional sampling at ultrahigh resolution without physically dissecting the organ allows the application of design-based stereology for assessment of the whole lung structure. Here we validate multiple stereological estimates performed on micro–computed tomography (μCT) images by comparing them with those obtained via conventional histology on the same mouse lungs. We explore and discuss the potentials and limitations of the two approaches. Histological examination offers higher resolution and the qualitative differentiation of tissues by staining, but ultimately loses 3-D tissue relationships, whereas μCT allows for the integration of morphometric data with the spatial complexity of lung structure. However, μCT has limited resolution satisfactory for the sterological estimates presented in this study but not for differentiation of tissues. We conclude that introducing stereological methods in μCT studies adds value by providing quantitative information on internal structures while not curtailing more complex approaches to the study of lung architecture in the context of physiological or pathological studies.
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Horálek, Vratislav, Viktor Beneš, and Vladimír Suchánek. "Stereology of Structures with Various Types of Spacing of Dispersed Spherical Particles Part 2: Estimation of Spatial Structure Parameters / Stereologische Untersuchung von Gefügen mit verschiedenen Typen der räumlichen Verteilung von dispergierten sphärischen Teilchen Teil 2: Berechnung der räumlichen Gefügeparameter." Practical Metallography 26, no. 1 (January 1, 1989): 25–34. http://dx.doi.org/10.1515/pm-1989-260105.

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Ohser, J., and F. Mücklich. "Stereology for some classes of polyhedrons." Advances in Applied Probability 27, no. 02 (June 1995): 384–96. http://dx.doi.org/10.1017/s0001867800026926.

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A general method for solving stereological problems for particle systems is applied to polyhedron structures. We suggested computing the kernel function of the respective stereological integral equation by means of computer simulation. Two models of random polyhedrons are investigated. First, regular prisms are considered which are described by their size and shape. The size-shape distribution of a stationary and isotropic spatial ensemble of regular prisms can be estimated from the size-shape distribution of the polygons observed in a section plane. Secondly, random polyhedrons are constructed as the convex hull of points which are uniformly distributed on surfaces of spheres. It is assumed that the size of the polyhedrons and the number of points (i.e. the number of vertices) are random variables. Then the distribution of a spatially distributed ensemble of polyhedrons is determined by its size-number distribution. The corresponding numerical density of this bivariate size-number distribution can be stereologically determined from the estimated numerical density of the bivariate size-number distribution of the intersection profiles.
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Ohser, J., and F. Mücklich. "Stereology for some classes of polyhedrons." Advances in Applied Probability 27, no. 2 (June 1995): 384–96. http://dx.doi.org/10.2307/1427832.

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A general method for solving stereological problems for particle systems is applied to polyhedron structures. We suggested computing the kernel function of the respective stereological integral equation by means of computer simulation. Two models of random polyhedrons are investigated. First, regular prisms are considered which are described by their size and shape. The size-shape distribution of a stationary and isotropic spatial ensemble of regular prisms can be estimated from the size-shape distribution of the polygons observed in a section plane. Secondly, random polyhedrons are constructed as the convex hull of points which are uniformly distributed on surfaces of spheres. It is assumed that the size of the polyhedrons and the number of points (i.e. the number of vertices) are random variables. Then the distribution of a spatially distributed ensemble of polyhedrons is determined by its size-number distribution. The corresponding numerical density of this bivariate size-number distribution can be stereologically determined from the estimated numerical density of the bivariate size-number distribution of the intersection profiles.
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Horálek, Vratislav, Viktor Beneš, and Vladimír Suchánek. "Stereology of Structures with Various Types ofSpacing of Dispersed Spherical Particles Part 3: Reducing the Influence of Resolution in Estimating Spatial Structure Parameters / Stereologische Untersuchung von Gefügen mit verschiedenen Typen derräumlichen Verteilung von dispergierten sphärischen Teilchen Teil 3: Verminderung des Einflusses der Auflösung auf die Ermittlung derräumlichen Gefügeparameter." Practical Metallography 26, no. 2 (February 1, 1989): 83–90. http://dx.doi.org/10.1515/pm-1989-260205.

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Jensen, E. B., and R. Sundberg. "Statistical Models for Stereological Inference about Spatial Structures: On the Applicability of Best Linear Unbiased Estimators in Stereology." Biometrics 42, no. 4 (December 1986): 735. http://dx.doi.org/10.2307/2530690.

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Dissertations / Theses on the topic "Spatial structure stereology"

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Moran, R. C. C. P. "Estimation of properties of spatial structures from sections." Thesis, University of Oxford, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.382656.

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