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Journal articles on the topic 'Solubility'

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Author: Grafiati

Published: 4 June 2021

Last updated: 29 July 2024

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1

Lajoie, Léo, Anne-Sylvie Fabiano-Tixier, and Farid Chemat. "Water as Green Solvent: Methods of Solubilisation and Extraction of Natural Products—Past, Present and Future Solutions." Pharmaceuticals 15, no. 12 (December 3, 2022): 1507. http://dx.doi.org/10.3390/ph15121507.

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Water is considered the greenest solvent. Nonetheless, the water solubility of natural products is still an incredibly challenging issue. Indeed, it is nearly impossible to solubilize or to extract many natural products properly using solely water due to their low solubility in this solvent. To address this issue, researchers have tried for decades to tune water properties to enhance its solvent potential in order to be able to solubilise or extract low-water solubility compounds. A few methods involving the use of solubilisers were described in the early 2000s. Since then, and particularly in recent years, additional methods have been described as useful to ensure the effective green extraction but also solubilisation of natural products using water as a solvent. Notably, combinations of these green methods unlock even higher extraction performances. This review aims to present, compare and analyse all promising methods and their relevant combinations to extract natural products from bioresources with water as solvent enhanced by green solubilisers and/or processes.

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2

Van Dyk, John W., Harry L. Frisch, and Dao T. Wu. "Solubility, solvency, and solubility parameters." Industrial & Engineering Chemistry Product Research and Development 24, no. 3 (September 1985): 473–78. http://dx.doi.org/10.1021/i300019a028.

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3

Aghnatios, C., R. Losno, and F. Dulac. "A fine fraction of soil used as an aerosol analogue during the DUNE experiment: sequential solubility in water, decreasing pH step-by-step." Biogeosciences 11, no. 17 (September 2, 2014): 4627–33. http://dx.doi.org/10.5194/bg-11-4627-2014.

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Abstract. A soil sample collected in a desert aerosol source area near Douz (southern Tunisia) was dry-sieved at 20 μm in order to extract the fraction similar to a wind-generated aerosol, and was used to seed mesocosms during the DUNE experiment (a DUst experiment in a low Nutrient, low chlorophyll Ecosystem). In this work, said "aerosol-like" fine dust was sequentially leached by short contacts with water at initial pHs, decreasing from seven to one, representing various wet environmental conditions. For each step, the solubility of a given element is calculated as the amount of its dissolved fraction, relative to its total amount. The evolution of this fractional solubility from the highest to lowest pHs provides information on the chemical strength needed to solubilise a given element and its lability. The behaviour of the elemental solubility was sorted into two groups: (1) Ca, Sr, Ba, Mn, and P, with a solubility between 23% and 70%, and a maximum sequential solubility at pH 3; (2) Al and Fe, with a solubility of less than 2% and the highest release at pH 1. Similar solubility patterns in group 1 for Ca, P, and Mn suggest a possible association of the elements in the same minerals, most probably carbonates.

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4

O'Brien, Geoffrey G. "Solubility." Iowa Review 30, no. 3 (December 2000): 52–53. http://dx.doi.org/10.17077/0021-065x.5323.

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5

Azimullah, Stanekzai, ,. Vikrant, CK Sudhakar, Pankaj Kumar, Akshay Patil, Md Rageeb Md. Usman, and Mohammed Zuber Shaikh Usman. "Nanosuspensions as a promising approach to enhance bioavailability of poorly soluble drugs : An update." Journal of Drug Delivery and Therapeutics 9, no. 2 (March 20, 2019): 574–82. http://dx.doi.org/10.22270/jddt.v9i2.2436.

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Solubility is a vital factor for devloping drug delivery systems for poorly water soluble drugs. Several conventional approaches for enhancement of solubility have limited applicability, especially when the drugs are poorly water soluble. Nanosuspension technology can be used to enhance the solubilty, stability as well as the bioavailability of poorly water soluble drugs. Nanosuspensions are biphasic systems comperising of pure drug particles dispersed in an aqueous vehicle, stabilized by surfac active agents. Fabrication of nanosuspension is simple and more advantageous than other approaches. Techniques like high-pressure homogenization, wet milling, emulsification, solvent evaporation, bottom up technology and top down technology have been applicable in the fabrication of nanosuspensions. Nanosuspension delivery is possible by several routes, such as oral, pulmonary, parenteral and ocular routes. Nanosuspension not only solves solubility and bioavailability issue, but improve drug safety and efficacy. In this context, we reviewed the current techniques used to develop nanosuspensions and their recents studies application in drug delivery system. Keywords : Solubility, fabrication, Characterization, Applications, Nanosuspension.

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6

Benne, Darja, and Harald Behrens. "Water solubility in haplobasaltic melts." European Journal of Mineralogy 15, no. 5 (November 17, 2003): 803–14. http://dx.doi.org/10.1127/0935-1221/2003/0015-0803.

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7

Bajait, Manoj Gajanan. "IMPORTANCE OF SOLUBILITY AND SOLUBILITY ENHANCEMENT TECHNIQUES." Journal of Medical Pharmaceutical And Allied Sciences 8, no. 6 (December 15, 2019): 2403–16. http://dx.doi.org/10.22270/jmpas.v8i6.878.

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8

Carpenter, John H. "Solubility Products and Solubility: Plus Ca Change?" Journal of Chemical Education 66, no. 2 (February 1989): 184. http://dx.doi.org/10.1021/ed066p184.

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9

Redelius, Per. "Bitumen Solubility Model Using Hansen Solubility Parameter." Energy & Fuels 18, no. 4 (July 2004): 1087–92. http://dx.doi.org/10.1021/ef0400058.

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10

Tessiri, Chanikanda, Sunee Channarong, and Paveena Wongtrakul. "Development of Aqueous Formulation Containing the Extracted Mangiferin." Key Engineering Materials 901 (October 8, 2021): 40–47. http://dx.doi.org/10.4028/www.scientific.net/kem.901.40.

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Mangiferin, a polyphenol of C-glycosylxanthone, exhibits various bioactivities with poor aqueous solubility. It is known as a potent antioxidant, which leads to remarkable UV protection and anti-aging properties. Mangiferin can be found in many plant species, among which the mango leaf is one of the primary sources. From our study, the extraction yield of mangifein obtained from the leaves of Mangifera indica L. variety Nam Doc Mai was 3.17% with 95.02% ± 0.064 purity (HPTLC analysis). The solubility of mangiferin in the studied pure solvents arranging in descending order were ethoxydiglycol, dimethyl isosorbide, polyethylene glycol 400, polyethylene glycol 600, propylene glycol, dipropylene glycol, glycerin, isopentyldiol, methanol, ethanol and water, whereas the addition of the solvent in water could increase the aqueous solubility of mangiferin. In several cases, the solubility was apparently higher than that dissolved in its pure solvent state. The log-linear solubility model for the cosolvent system was used to calculate the volume fractions of the selected solvents needed to solubilize mangiferin content at the twenty times of the IC50 against DPPH radicals. In conclusion, the developed aqueous formulation contained 0.5% w/v of mangiferin and 20% w/v of polyethylene glycol 600 or dipropylene glycol as a solubilizer in water.

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11

Thorn, Andrew. "Safer Solubility." Studies in Conservation 37, no. 1 (February 1992): 12. http://dx.doi.org/10.2307/1506433.

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12

Thorn, Andrew. "Safer solubility." Studies in Conservation 37, no. 1 (January 1992): 12–21. http://dx.doi.org/10.1179/sic.1992.37.1.12.

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13

Vaibhav Gulabrao Bhamare, Renuka Ravindra Joshi, Mayur Sakharam Gangurde, and Vijay V Pawar. "Theoretical consideration of solubility by Hildebrand solubility approach." World Journal of Advanced Research and Reviews 12, no. 3 (December 30, 2021): 528–41. http://dx.doi.org/10.30574/wjarr.2021.12.3.0680.

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Pharmaceutical field is widely focusing on solubility parameter models to select solvent or non-solvent that can enhance solvency of drug. Solubility Parameter is very useful concept in understanding the mechanism of solvent and solvency behavior with their applications in pharmaceuticals to open the door of research having focus on theoretical considerations of solubility. Hildebrand and Hansen Solubility Parameter are frequently used to identify solvents.

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14

Ibrahim, Naz, Shahla Smail, Nozad Hussein, and Tara Abdullah. "Solubility enhancement of nimodipine using mixed hydrotropic solid dispersion technique." Zanco Journal of Medical Sciences 24, no. 3 (December 25, 2020): 386–94. http://dx.doi.org/10.15218/zjms.2020.046.

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Background and objective: Low aqueous solubility of active pharmaceutical ingredients has an effect on both formulation development and bioavailability. Nimodipine is an antihypertensive agent with low oral bioavailability, which might be attributed to the extremely poor water solubility. This study aimed to increase the solubility of nimodipine in water using hydrotropes and solid dispersion technology to increase dissolution rate compared to the marketed drug product. Methods: Solubility of nimodipine was determined separately in sodium acetate, sodium citrate, sodium benzoate, and niacinamide solutions at a concentration of 10, 20, 30, and 40% w/v using distilled water as a solvent. The highest solubility was obtained in 40% sodium benzoate solution. Mixed concentrations of hydrotropic agents were used in ratio 1:3 (niacinamide: sodium benzoate). Fourier-transform infrared spectroscopy was used to exclude any drug-hydrotropes interaction. The dissolution rate of nimodipine from solid dispersion and physical mixture were studied using USP type II dissolution test apparatus in acetate buffer (pH 4.5) as a dissolution media. Results: Hydrotropic solid dispersion of nimodipine with a blend (30% sodium benzoate and 10% niacinamide) increased the dissolution rate of the drug by 1.5 folds compared to the marketed conventional nimodipine tablet. Fourier-transform infrared analysis did not show any physicochemical interaction between drug and carriers in solid dispersion formulation. Conclusion: The hydrotrop is a novel and safe compound. It is a successful way to enhance the solubility of poorly aqueous soluble drugs. Immediate dissolution of practically insoluble drug nimodipine in dissolution media indicates that it has a great potential to solubilize the drug in biological fluids. Thus, a considerable improvement in bioavailability and onset of action of the drug can be predictable. Adding of a hydrotropic agent with nimodipine in solid dispersion increased the dissolution rate of the drug compared to the marketed conventional nimodipine tablet Keywords: Hydrotropes; Nimodipine; Solubility enhancement; Solid dispersion.

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15

Arianie, Lucy. "Potention of Lignin, Lignin Sulfonate and Lignin Acetate from Palm Empty Bunch as an Additive Substance in Urea Fertilizer as an Effort to Reduce the Solubility of Urea Nitrogen." Advanced Materials Research 93-94 (January 2010): 409–12. http://dx.doi.org/10.4028/www.scientific.net/amr.93-94.409.

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Hydrophobic lignin’s character is used as the base of lignin usage as the binder in the urea fertilizer tablet. Lignin was isolated from black liquor of pulp and paper with palm empty bunch materials. Sulfonation of lignin isolate produced lignin sulfonate. Acetylation of lignin isolate produced lignin acetate. Lignin, lignin sulfonate and lignin acetate analyzed its solubility showed that lignin has no solubility in water. Therefore, urea fertilizer need to be modified by lignin. Nitrogen concentration of tablet lignin – urea with variation of lignin percentage 1,2,3,4 and 5 % examined with Kjehdahl method, produced nitrogen concentration in average 43%. Binding lignin isolate with percentage of 1 – 5 % to commercial urea fertilizer formed lignin – urea tablet. Its solubility test showed that lignin – urea formation will dissolve in 96 ; 137 ; 435 ; 759 ; 625 seconds, respectively. As control was commercial urea fertilizer with solubility’s time is 142 seconds.

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16

Nainwal, Nidhi, Ranjit Singh, Sunil Jawla, and Vikas Anand Saharan. "The Solubility-Permeability Interplay for Solubility-Enabling Oral Formulations." Current Drug Targets 20, no. 14 (October 14, 2019): 1434–46. http://dx.doi.org/10.2174/1389450120666190717114521.

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The Biopharmaceutical classification system (BCS) classifies the drugs based on their intrinsic solubility and intestinal permeability. The drugs with good solubility and intestinal permeability have good bioavailability. The drugs with poor solubility and poor permeability have solubility dependent and permeability dependent bioavailability, respectively. In the current pharmaceutical field, most of the drugs have poor solubility. To solve the problem of poor solubility, various solubility enhancement approaches have been successfully used. The effects of these solubility enhancing approaches on the intestinal permeability of the drugs are a matter of concern, and must not be overlooked. The current review article focuses on the effect of various solubility enhancing approaches viz. cyclodextrin, surfactant, cosolvent, hydrotropes, and amorphous solid dispersion, on the intestinal permeability of drugs. This article will help in the designing of the optimized formulations having balanced solubility enhancement without affecting the permeability of drugs.

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17

Hewitt, M., M. T. D. Cronin, S. J. Enoch, J. C. Madden, D. W. Roberts, and J. C. Dearden. "In Silico Prediction of Aqueous Solubility: The Solubility Challenge." Journal of Chemical Information and Modeling 49, no. 11 (November 2, 2009): 2572–87. http://dx.doi.org/10.1021/ci900286s.

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18

Lou, Yuecun, Pingjiao Hao, and Glenn Lipscomb. "NELF predictions of a solubility–solubility selectivity upper bound." Journal of Membrane Science 455 (April 2014): 247–53. http://dx.doi.org/10.1016/j.memsci.2013.12.071.

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19

Saal, Christoph, and Anna Christine Petereit. "Optimizing solubility: Kinetic versus thermodynamic solubility temptations and risks." European Journal of Pharmaceutical Sciences 47, no. 3 (October 2012): 589–95. http://dx.doi.org/10.1016/j.ejps.2012.07.019.

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20

Buchowski, H., and A. Khiat. "Solubility of solids in liquids: one-parameter solubility equation." Fluid Phase Equilibria 25, no. 3 (January 1986): 273–78. http://dx.doi.org/10.1016/0378-3812(86)80003-6.

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21

Pinal, Rodolfo, and Samuel H. Yalkowsky. "Solubility and Partitioning VII: Solubility of Barbiturates in Water." Journal of Pharmaceutical Sciences 76, no. 1 (January 1987): 75–85. http://dx.doi.org/10.1002/jps.2600760120.

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22

Pinal, Rodolfo, and Samuel H. Yalkowsky. "Solubility and Partitioning IX: Solubility of Hydantoins in Water." Journal of Pharmaceutical Sciences 77, no. 6 (June 1988): 518–22. http://dx.doi.org/10.1002/jps.2600770611.

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23

Mattigod, Shas V., Dhanpat Rai, Andrew R. Felmy, and Linfeng Rao. "Solubility and solubility product of crystalline Ni(OH)2." Journal of Solution Chemistry 26, no. 4 (April 1997): 391–403. http://dx.doi.org/10.1007/bf02767678.

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24

Pigeon, Pascal, Feten Najlaoui, Michael James McGlinchey, Juan Sanz García, Gérard Jaouen, and Stéphane Gibaud. "Unravelling the Role of Uncommon Hydrogen Bonds in Cyclodextrin Ferrociphenol Supramolecular Complexes: A Computational Modelling and Experimental Study." International Journal of Molecular Sciences 24, no. 15 (July 31, 2023): 12288. http://dx.doi.org/10.3390/ijms241512288.

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We sought to determine the cyclodextrins (CDs) best suited to solubilize a patented succinimido-ferrocidiphenol (SuccFerr), a compound from the ferrociphenol family having powerful anticancer activity but low water solubility. Phase solubility experiments and computational modelling were carried out on various CDs. For the latter, several CD-SuccFerr complexes were built starting from combinations of one or two CD(s) where the methylation of CD oxygen atoms was systematically changed to end up with a database of ca. 13 k models. Modelling and phase solubility experiments seem to indicate the predominance of supramolecular assemblies of SuccFerr with two CDs and the superiority of randomly methylated β-cyclodextrins (RAMEβCDs). In addition, modelling shows that there are several competing combinations of inserted moieties of SuccFerr. Furthermore, the models show that ferrocene can contribute to high stabilization by making atypical hydrogen bonds between Fe and the hydroxyl groups of CDs (single bond with one OH or clamp with two OH of the same glucose unit).

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25

Hasanova, Z. T. "SOLUBILITY OF GERMANIUM DISELENIDE IN THE Cu3AsSe4." Azerbaijan Chemical Journal, no. 4 (December 8, 2021): 67–70. http://dx.doi.org/10.32737/0005-2531-2021-4-67-70.

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Differential thermal analysis and powder X-ray diffraction methods were used for phase equilibria studying in the Cu3AsSe4-GeSe2 system. It was established that wide (up to 30 mol.%) solid solutions based on Cu3AsSe4 are formed. GeSe2-rich alloys consist of various heterogeneous mixtures, including phases outside the T–x plane of this section

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26

Dutchak, Vasyl, Olena Astakhova, and Leonid Kvitkovsky. "Reciprocal Solubility of Gasoline Fractions and Ethanol." Chemistry & Chemical Technology 5, no. 2 (June 15, 2011): 215–20. http://dx.doi.org/10.23939/chcht05.02.215.

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27

Ahirrao, Sapana P., Kishor S. Rathi, Diksha B. Koli, Sanjay J. Kshirsagar, and Sarita Pawar. "SOLUBILITY ENHANCEMENT OF NITAZOXANIDE USING SOLID DISPERSION." Indian Research Journal of Pharmacy and Science 5, no. 4 (December 2018): 1674–87. http://dx.doi.org/10.21276/irjps.2018.5.4.6.

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28

Kaur, Gurleen, Alfisha Saifi, Kapil Kumar, and Deepak Teotia. "Development and Evaluation of Micro Emulsion Formulations of Nebivolol for Solubility Enhancement." Journal of Drug Delivery and Therapeutics 11, no. 5 (September 15, 2021): 84–89. http://dx.doi.org/10.22270/jddt.v11i5.5005.

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Nebivolol HCl is a newer drug of β1-adrenergic blocker category, basically used as anti-hypertensive. It is a 3rd generation, antagonist, having NO (nitric oxide) enhancing vasodilator properties. It has 12% oral bioavailability, because of its pre systemic metabolism by the means of cytochrome P450 2D6 enzymes. Its log P value is 4.03 and 5mg is its daily dose. It is highly lipophilic drug and belongs to class BCS II, with slow dissolution. Bioavailability of any drug can be improved by avoiding its first pass metabolism and promoting solubility. Several researchers have worked on the development of ME formulations on different poor water-soluble drugs, to increase their solubility. The purpose of this study is an attempt to enhance the solubility to improve the bioavailability of nebivolol drug by developing a novel delivery system that is microemulsion (ME) .ME formulations were developed using different oil, surfactant and co-surfactants in different ratio and studied on various parameters. Different preformulation tests done on received sample of Nebivolol. FTIR study was performed in order to find out any interactions between the ingredients. Based on the solubility Capmul Pg-12 was finalized oil, Tween 80 as surfactant, propylene glycol as the cosurfactant based on solubility and emulsification efficiency. Five Nebivolol ME formulations were successfully developed by use of oil, water, SA and Co-SA different ratio. Prepared formulations were studied for different properties- transmittance (%), pH, refractive index, viscosity, drug content, and solubility. It was seen that after 4 hours of diffusion, the drug released from the formulation ME5 is faster and more than that of the other i.e., 90.2±0.06%. It was found that ME5 was more stable and Soluble than other prepared formulations. With the better solubilty the bioavailability of Nebivolol will increased and helps in faster absorption and High diffusion in systemic circulation with lower or no risk of degradation. It somehow also reduced frequent intake of drug. Keywords: Nebivolol, micro emulsion, Ternary phase diagram, surfactant, co-surfactant.

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29

Asim Mushtaq, Asim Mushtaq, and Hilmi Mukhtar and Azmi Mohd Shariff Hilmi Mukhtar and Azmi Mohd Shariff. "Solubility Parameter Study of Polysulfone, Polyvinyl Acetate in Dimethylacetamide Solvent." Journal of the chemical society of pakistan 41, no. 1 (2019): 203. http://dx.doi.org/10.52568/000726/jcsp/41.01.2019.

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The solubility parameter is calculated to express the magnitude and nature of the interactive forces between the polymers and solvents. It measures the affinity between the components of a mixture. To improve the prediction of the solubility parameter, the group contribution method is used to calculate the overall solubility parameter as suggested by Hildebrand. Hildebrand’s method is used to predict the interaction between the polymers and solvent. In this study, calculate the solubility parameters of polysulfone (PSU), polyvinyl acetate (PVAc) polymers and dimethylacetamide (DMAc) solvent by Hildebrand method. The PSU and PVAc solubility were found to be 1.52H and 1.7H, respectively. These solubility values show that both polymers were dissolved readily in the DMAc solvent, resulting in a true solution.

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30

Singh, Narinder, Amar Pal Singh, and Ajeet Pal Singh. "Solubility: An overview." International Journal of Pharmaceutical Chemistry and Analysis 7, no. 4 (January 15, 2021): 166–71. http://dx.doi.org/10.18231/j.ijpca.2020.027.

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31

Mamardashvili, Galina, Nugdzar Mamardashvili, and Boris Berezin. "Solubility of Alkylporphyrins." Molecules 5, no. 12 (June 7, 2000): 762–66. http://dx.doi.org/10.3390/50600762.

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32

Marcus, Yizhak, Allan L. Smith, M. V. Korobov, A. L. Mirakyan, N. V. Avramenko, and E. B. Stukalin. "Solubility of C60Fullerene." Journal of Physical Chemistry B 105, no. 13 (April 2001): 2499–506. http://dx.doi.org/10.1021/jp0023720.

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33

Eger, EI. "ANESTHETIC PLASTIC SOLUBILITY." Anesthesiology 69, no. 3A (September 1, 1988): A297. http://dx.doi.org/10.1097/00000542-198809010-00296.

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34

Kachalina, О. V., and A. A. Korenkova. "Cervical endometriosis – solubility." Medical Council, no. 21 (January 20, 2019): 174–77. http://dx.doi.org/10.21518/2079-701x-2018-21-174-177.

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Cervical endometriosis is a common disease in young women, which is characterized by the appearance of tissue on the vaginal part of the cervix, similar in structure to the endometrium and undergoing cyclic changes in accordance with the menstrual cycle, and is a form of external genital endometriosis. The article presents the pathogenetic mechanisms of this disease development in terms of possibility of exposure to them during pathogenetic therapy.

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35

Sinclair, Meeghan. "Monitoring protein solubility." Nature Biotechnology 19, no. 2 (February 2001): 101. http://dx.doi.org/10.1038/84325.

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36

Marshall, Andrew. "Photoreversible enzyme solubility." Nature Biotechnology 17, no. 1 (January 1999): 10. http://dx.doi.org/10.1038/5356.

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37

Clever, H. Lawrence. "Solubility of mercury." Journal of Chemical Education 62, no. 8 (August 1985): 720. http://dx.doi.org/10.1021/ed062p720.2.

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38

Gildea, Brian D., Shelagh Casey, Joan MacNeill, Heather Perry-O'Keefe, Ditte Sørensen, and James M. Coull. "PNA solubility enhancers." Tetrahedron Letters 39, no. 40 (October 1998): 7255–58. http://dx.doi.org/10.1016/s0040-4039(98)01581-0.

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39

Wolf, B. A. "Solubility of polymers." Pure and Applied Chemistry 57, no. 2 (January 1, 1985): 323–36. http://dx.doi.org/10.1351/pac198557020323.

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40

Ewing, F., E. Forsythe, and M. Pusey. "Orthorhombic lysozyme solubility." Acta Crystallographica Section D Biological Crystallography 50, no. 4 (July 1, 1994): 424–28. http://dx.doi.org/10.1107/s0907444993014428.

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41

Darrow, Frank W. "Solubility (Hallgren, Richard)." Journal of Chemical Education 66, no. 1 (January 1989): A43. http://dx.doi.org/10.1021/ed066pa43.

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42

Corkern, Walter H., and Linda L. Munchausen. "Solubility of alcohols." Journal of Chemical Education 69, no. 11 (November 1992): 928. http://dx.doi.org/10.1021/ed069p928.1.

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43

Avdeef, Alex, and Cynthia M. Berger. "pH-metric solubility." European Journal of Pharmaceutical Sciences 14, no. 4 (December 2001): 281–91. http://dx.doi.org/10.1016/s0928-0987(01)00190-7.

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44

Rizzi, L. G., and S. Auer. "Amyloid Fibril Solubility." Journal of Physical Chemistry B 119, no. 46 (November 5, 2015): 14631–36. http://dx.doi.org/10.1021/acs.jpcb.5b09210.

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45

Butina, Darko, and Joelle M. R. Gola. "Modeling Aqueous Solubility." Journal of Chemical Information and Computer Sciences 43, no. 3 (May 2003): 837–41. http://dx.doi.org/10.1021/ci020279y.

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46

Asherie, Neer, Charles Ginsberg, Samuel Blass, Arieh Greenbaum, and Sarah Knafo. "Solubility of Thaumatin." Crystal Growth & Design 8, no. 6 (June 2008): 1815–17. http://dx.doi.org/10.1021/cg800276r.

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47

Beck, Mihály T., and Géza Mándi. "Solubility of C60." Fullerene Science and Technology 5, no. 2 (March 1997): 291–310. http://dx.doi.org/10.1080/15363839708011993.

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48

van Oss, C. J., R. J. Good, and M. K. Chaudhury. "Solubility of proteins." Journal of Protein Chemistry 5, no. 6 (December 1986): 385–405. http://dx.doi.org/10.1007/bf01025572.

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49

Schein, Catherine H. "Solubility and secretability." Current Opinion in Biotechnology 4, no. 4 (August 1993): 456–61. http://dx.doi.org/10.1016/0958-1669(93)90012-l.

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50

Michałowska-Kaczmarczyk, Anna Maria, and Tadeusz Michałowski. "Solubility product challenge." Analytical and Bioanalytical Chemistry 407, no. 7 (February 21, 2015): 1789–91. http://dx.doi.org/10.1007/s00216-014-8407-2.

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