Academic literature on the topic 'Solid liver lesions'

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Journal articles on the topic "Solid liver lesions"

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Morana, Giovanni, Luigi Grazioli, Miles A. Kirchin, Maria Pia Bondioni, Niccolò Faccioli, Alessandro Guarise, and Günther Schneider. "Solid Hypervascular Liver Lesions." Investigative Radiology 46, no. 4 (April 2011): 225–39. http://dx.doi.org/10.1097/rli.0b013e3181feee3a.

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Nalaini, Farhad, Fatemeh Shahbazi, Seyedeh Maryam Mousavinezhad, Ali Ansari, and Mohammadgharib Salehi. "Diagnostic accuracy of apparent diffusion coefficient (ADC) value in differentiating malignant from benign solid liver lesions: a systematic review and meta-analysis." British Journal of Radiology 94, no. 1123 (July 1, 2021): 20210059. http://dx.doi.org/10.1259/bjr.20210059.

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Objectives: We undertook a systematic review and meta-analysis of the diagnostic performance of mean apparent diffusion coefficient (ADC) values derived by diffusion-weighted (DW)-MRI in the characterization of solid benign and malignant liver lesions, and to assess their value in discriminating these lesions in daily routine practice. Methods: A systematic review of PubMed, Embase, Scopus, and Web of Science was conducted to retrieve studies that used ADC values for differentiating solid benign/dysplastic nodules and malignant liver lesions. A bivariate random-effects model with pooled sensitivity and specificity values with 95% CI (confidence interval) was used. This meta-analysis was performed on the per-lesion basis. Summary receiver operating characteristic (SROC) plot and area under curve (AUC) were created. Results: A total of 14 original articles were retrieved. The combined (95% CI) sensitivity and specificity of mean ADC values for differentiating solid benign from malignant lesions were 78% (67–86%) and 74% (64–81%), respectively. The pooled (95% CI) positive and negative LRs were respectively 3 (2.3–3.8) and 0.3 (0.21–0.43). The DOR (95% CI) was 10 (7–15). The AUC (95% CI) of the SROC plot was 82% (78–85%). Reporting bias was negligible (p value of regression test = 0.36). Mean size of malignant lesions and breathing pattern of MRI were found to be sources of heterogeneity of pooled sensitivity. Conclusion: ADC measurement independently may not be an optimal diagnostic imaging method for differentiating solid malignant from solid benign hepatic lesions. The meta-analysis showed that ADC measurement had moderate diagnostic accuracy for characterizing solid liver lesions. Further prospective and comparative studies with pre-specified ADC thresholds could be performed to investigate the best MRI protocol and ADC threshold for characterizing solid liver lesions. Advances in knowledge: ADC measurement by DW-MRI does not have a good diagnostic performance to differentiate solid malignant from solid benign lesions. Therefore, we suggest not using ADC values in clinical practice to evaluate solid liver lesions.
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Wu, Size, Dongsheng Zuo, and Yamin Hong. "The Prevalence of Hyperechoic Rim in Solid Focal Liver Lesions and Its Implication." Journal of Diagnostic Medical Sonography 35, no. 1 (September 7, 2018): 3–8. http://dx.doi.org/10.1177/8756479318798365.

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The objective of this study was to investigate the prevalence and clinical implications of the hyperechoic rim of liver focal solid lesions. A retrospective review was conducted of sonograms of focal liver lesions with a hyperechoic rim, as well as relative examinations such as computed tomography, magnetic resonance imaging, biopsy, resection, and histopathology reports. A cohort of 10 232 patients was found to have solid focal liver lesions (2030 malignant, 8202 benign). A hyperechoic rim was determined in 182 hemangiomas, 2 granulomas, 2 hepatocellular carcinomas (HCCs), and 4 other malignancies. There were significant differences between malignant and benign lesions ( P < .001), between HCCs and hemangiomas ( P < .001), between malignancies and hemangiomas ( P < .001), between HCCs and granulomas ( P = .044), and between other malignancies and granulomas ( P = .005). There was no significant difference between liver granulomas and hemangiomas ( P = .656). In this study, a hyperechoic rim in solid focal liver lesions appeared mainly in hemangiomas, granulomas, and rarely in malignant lesions.
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Belghiti, Jacques, François Cauchy, Valérie Paradis, and Valérie Vilgrain. "Diagnosis and management of solid benign liver lesions." Nature Reviews Gastroenterology & Hepatology 11, no. 12 (September 2, 2014): 737–49. http://dx.doi.org/10.1038/nrgastro.2014.151.

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Wasif, Nabil, Sebastian Sasu, William C. Conway, and Anton Bilchik. "Focal Nodular Hyperplasia: Report of an Unusual Case and Review of the Literature." American Surgeon 74, no. 11 (November 2008): 1100–1103. http://dx.doi.org/10.1177/000313480807401112.

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Focal nodular hyperplasia (FNH) is the second most common benign lesion of the liver and a common differential in the workup of solid liver lesions. With increasing use of modern imaging modalities FNH is becoming clinically more relevant. We present a case of pedunculated FNH presenting as a pericholecystic mass. This was resected laparoscopically due to persistent symptoms and uncertainty in diagnosis. We summarize the current literature with regard to the diagnosis, etiology, and management of FNH lesions.
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Sbeit, Wisam, Anas Kadah, Amir Mari, Mahmud Mahamid, and Tawfik Khoury. "A Comprehensive Narrative Review on the Evolving Role of Endoscopic Ultrasound in Focal Solid Liver Lesions Diagnosis and Management." Diagnostics 10, no. 9 (September 11, 2020): 688. http://dx.doi.org/10.3390/diagnostics10090688.

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The implications of endoscopic ultrasound (EUS) have expanded considerably in recent years to cover more fields in invasive gastroenterology practice, as both an investigative and therapeutic modality. The utility of EUS in the diagnosis and management of focal liver lesions has gained a special attractiveness recently. The EUS probe proximity to the liver and its excellent spatial resolution enables real-time images coupled with several enhancement techniques, such as contrast-enhanced (CE) EUS. Aside from its notable capability to execute targeted biopsies and therapeutic interventions, EUS has developed into a hopeful therapeutic tool for the management of solid liver lesions. Herein, we provide a comprehensive state-of-the-art review on the efficacy and safety of EUS in the diagnosis and management of focal solid liver lesions. Medline/PubMed and Embase database searches were conducted by two separate authors (T.K. and W.S.), all relevant studies were assessed, and relevant data was extracted and fully reported. EUS-guided diagnosis of focal liver lesions by sonographic morphologic appearance and cytological and histopathological finding of biopsies obtained via fine needle aspiration/biopsy have been shown to significantly improve the diagnosis of solid liver lesions compared with traditional imaging tools. Similarly, EUS-guided treatment has been shown to consistently have excellent technical success, high efficacy, and minor adverse events. The evolving valuable evidences of EUS utility might satisfy the unmet need of optimizing management of focal solid liver lesions.
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Bariş, Zeren, Pelin Börcek, Kemal Murat Haberal, and Figen Özçay. "Solid Liver Lesions in an Infant With Neonatal Cholestasis." Journal of Pediatric Hematology/Oncology 39, no. 8 (November 2017): 626–28. http://dx.doi.org/10.1097/mph.0000000000000936.

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Mondragón-Sánchez, Ricardo, Elvira Gómez-Gómez, Ana Lilia Garduño-López, Alejandro Mondragón-Sánchez, M. Nancy Martínez-González, and Juan Manuel Ruiz-Molina. "Surgical management of benign solid and cystic liver lesions." Clinical and Translational Oncology 6, no. 5 (June 2004): 295–301. http://dx.doi.org/10.1007/bf02711837.

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Balekuduru, Avinash Bhat, Amit Kumar Dutta, Sanjeev Kumar Nagaruru, Shamim Sheik, Suneetha Parandhamaiah Kurella, and Satyaprakash Bonthala Subbaraj. "Comparison of Diagnostic Yield of Endoscopic Ultrasound-guided Fine-needle Aspiration Cytology and Cell Block in Solid Lesions." Journal of Digestive Endoscopy 08, no. 04 (October 2017): 176–81. http://dx.doi.org/10.4103/jde.jde_53_17.

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ABSTRACT Background and Aim: Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is a procedure of choice for the diagnostic evaluation of submucosal and periluminal lesions. Tissue sample can be obtained by EUS-FNA cytology (FNAC) or cell block (CB). The aim of the present study is to compare diagnostic yield of EUS-FNA CB and cytology in the absence of onsite pathologist following a protocol-based EUS-FNA approach in solid lesions. Patients and Methods: Participants who underwent EUS-FNA at our center for solid submucosal or periluminal lesions (pancreas, lymph node, and liver) between 2014 and 2016 were included, retrospectively. The indication for the procedure along with the clinical and other investigation details and the final etiological diagnosis were recorded on uniform structured data forms. The diagnostic yield of cytology and CB were compared using McNemar’s test. The P < 0.05 was considered statistically significant. Results: EUS-FNA for solid lesion was performed in 130 lesions in 101 patients during the study period. Their mean age was 52.5 ± 12 years and 42.5% were female. Pancreatic masses were the most common lesions (37.7%) followed by lymph nodes (36.9%). Submucosal lesions (17.7%) and liver lesions (7.7%) accounted for rest of the cases. The overall diagnostic yield for EUS-FNAC (70%) and CB (74.6%) was not significantly different (P = 0.3) and their combined yield was 85.3%. For the 23 patients with submucosal lesion, diagnostic yield of CB (82.6%) was significantly better than cytology (47.8%, P = 0.04). Conclusions: EUS-guided CB has better yield compared to cytology in gastrointestinal submucosal lesions. The combination of CB with cytology improves the overall yield of the procedure; and hence, they should be considered complimentary rather than alternatives.
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Yang, Da-wei, Ke-yang Wang, Xun Yao, Hui-yi Ye, Tao Jiang, Yuan Liu, Jia-yin Gao, Min Chen, Cheng Zhou, and Zheng-han Yang. "Diffusion-Weighted Imaging with Two Differentb-Values in Detection of Solid Focal Liver Lesions." BioMed Research International 2016 (2016): 1–9. http://dx.doi.org/10.1155/2016/8128207.

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One hundred and eighty-two consecutive patients with suspected liver disease were recruited to receive diffusion-weighted imaging (DWI) with two differentb-values, in comparison with T2-weighted imaging (T2WI). The detection rate of three MR sequences in solid focal liver lesions (FLLs) and subgroup analyses were performed. Our prospective study found that DWI600 was equivalent to DWI100 and T2WI for the detection of solid FLLs overall but was significantly more accurate in the detection of malignant solid FLLs and lesions larger than 10 mm.
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Dissertations / Theses on the topic "Solid liver lesions"

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ABU, HILAL Moh'D. "The role of laparoscopic surgery in the management of liver lesions." Doctoral thesis, 2011. http://hdl.handle.net/11562/349105.

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Laparoscopic liver surgery has been late to find popularity when compared to other surgical fields. This is understandable due to the well know technical difficulties when dealing with the liver parenchyma, the significant risk of bleeding and the doubts about its oncological efficiency. However thanks to encouraging results from a handful of enthusiastic surgeons it is now starting to gain notable expansion especially when minor resections are needed. In this these I aim to study the development of laparoscopic liver surgery analysing our experience and by reviewing the literature. For this I discuss separately the different aspects of this new approach starting with the feasibility of minor and major laparoscopic liver resections and discussing the surgical techniques adopted in our centre. I also discuss the risks of this approach demonstrating it safety in terms of intra and post operative outcome. The oncological efficiency has been at the centre of many debates in the last few years , here I discuss our oncological results in terms of resection margins, peritoneal seeding and port site metastasis. Last but not least in this dissertation, I discuss the financial aspect of this mini invasive approach showing that despite an increased intra operative cost in laparoscopic procedures, the overall cost is comparable when compared with open procedures. In conclusion, laparoscopic liver surgery was shown to be feasible , safe, oncologicaly efficient and cost effective when compared to open surgery.
Laparoscopic liver surgery has been late to find popularity when compared to other surgical fields. This is understandable due to the well know technical difficulties when dealing with the liver parenchyma, the significant risk of bleeding and the doubts about its oncological efficiency. However thanks to encouraging results from a handful of enthusiastic surgeons it is now starting to gain notable expansion especially when minor resections are needed. In this these I aim to study the development of laparoscopic liver surgery analysing our experience and by reviewing the literature. For this I discuss separately the different aspects of this new approach starting with the feasibility of minor and major laparoscopic liver resections and discussing the surgical techniques adopted in our centre. I also discuss the risks of this approach demonstrating it safety in terms of intra and post operative outcome. The oncological efficiency has been at the centre of many debates in the last few years , here I discuss our oncological results in terms of resection margins, peritoneal seeding and port site metastasis. Last but not least in this dissertation, I discuss the financial aspect of this mini invasive approach showing that despite an increased intra operative cost in laparoscopic procedures, the overall cost is comparable when compared with open procedures. In conclusion, laparoscopic liver surgery was shown to be feasible , safe, oncologicaly efficient and cost effective when compared to open surgery.
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Book chapters on the topic "Solid liver lesions"

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Altun, Ersan, Mohamed El-Azzazi, Richard C. Semelka, and Mamdoh AlObaidy. "Benign solid liver lesions." In Liver imaging: MRI with CT correlation, 101–36. Hoboken, NJ, USA: John Wiley & Sons, Inc, 2015. http://dx.doi.org/10.1002/9781118484852.ch5.

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Cheng, Zhigang, and Ping Liang. "Percutaneous Microwave Ablation for Benign Focal Liver Lesions." In Microwave Ablation Treatment of Solid Tumors, 53–63. Dordrecht: Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-017-9315-5_5.

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Fogelman, David, and Robert A. Wolff. "Management of solid and cystic lesions of the pancreas." In Laparoscopic Liver, Pancreas, and Biliary Surgery, 298–321. Chichester, UK: John Wiley & Sons, Ltd, 2016. http://dx.doi.org/10.1002/9781118781166.ch22.

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Chow, Jeanne S. "Solid and Cystic Masses and Mass-Like Lesions of the Liver, Bile Ducts, and Pancreas." In Diseases of the Abdomen and Pelvis 2014–2017, 271–78. Milano: Springer Milan, 2014. http://dx.doi.org/10.1007/978-88-470-5659-6_36.

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"Benign Solid Liver Lesions." In Diagnostic Imaging: Nuclear Medicine, 86–89. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-323-37753-9.50029-3.

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"Benign Solid Focal Lesions and Incidentalomas of the Liver." In Principles of Hepatic Surgery, edited by Silvio Balzan, Vinicius Gava, and Gustavo Luersen, 295–323. BENTHAM SCIENCE PUBLISHERS, 2016. http://dx.doi.org/10.2174/9781681082851116010022.

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Lee, Christine U., and James F. Glockner. "Case 11.15." In Mayo Clinic Body MRI Case Review, edited by Christine U. Lee and James F. Glockner, 554–55. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199915705.003.0293.

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70-year-old woman with a history of ovarian carcinoma Coronal SSFSE images (Figure 11.15.1) demonstrate a large, predominantly solid right adnexal mass, with a simple-appearing cystic lesion in the left ovary. Note the abdominal pelvic ascites and small solid nodules between the diaphragm and liver, as well as confluent omental masses below the transverse colon on the most anterior image. Axial diffusion-weighted images (b=600 s/mm...
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Conference papers on the topic "Solid liver lesions"

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Jethwani, Umesh, and Divya Jethwani. "Sertoli cell tumor of ovary: A rare case report." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685324.

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Introduction: Sertoli-Leydig cell tumor (SLCT) is a rare ovarian tumor, Constitute less than 0.5% of ovarian tumors. Most tumors are unilateral, confined to the ovaries. They are seen during the second and third decades of life. They are characterized by the presence of testicular structures that produce androgens. Patients have symptoms of virilization (depending on the quantity of androgen). Case Report: A 42-year-old woman presented Amenorrhea for 14 months. Change in her voice for 1 year and Excessive hair growth on her face, chest, and limbs for the last 2 months. She complained of vague abdominal discomfort. No history of anorexia, weight loss, increased libido. Her medical and family history was unremarkable. On examination - Hirsutism and clitoromegaly. Lump of size 10x8 cm palpable in left iliac fossa. Vaginal examination revealed a firm and mobile cystic mass in the right adnexa. An ultrasound examination of the pelvis showed a 17x 13x 9-cm heterogeneous solid cystic mass replacing the left ovary. The right ovary and the uterus were normal. CECT Scan Abdomen-Large heterogenous encapsulated solid soft tissue mass lesions containing areas of calcification arising from left ovary of size 17x13x10.6cm causing displacement of urinary bladder and surrounding bowel loops. Serum testosterone level -2 ng/mL (normal, 0.2–1.2 ng/mL); (DHEAS), CA 125, and alpha fetoprotein (AFP) -normal. On Laparotmy-Large mass of size 17 X 13 cm arising from left adnexa. Uterus and right ovary grossly normal. Total Abdominal hysterectomy, B/L Salpingo-opherectomy and infracolic omentectomy was done. Peritoneal washing were sent for cytologic examination for malignant cells. No liver metastasis. The post operative period was uneventful. Histopathology revealed- confirmed it be Sertoli Leydig cell tumor. 3month follow up – resolution of her virilization symptoms. No increase of her hirsutism. Repeat testosterone levels - within normal range. Conclusion: Only few cases of SLCT have been reported till date Prognosis depends on extent of disease, stage of disease, tumour differentiation, grade. The treatment should be individualized according to the location, state of spread and the patient’s condition.
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