Academic literature on the topic 'Sm like'

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Journal articles on the topic "Sm like"

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Arluison, Véronique, Cameron Mura, Maria Romero Guzmán, Jean Liquier, Olivier Pellegrini, Mari Gingery, Philippe Régnier, and Sergio Marco. "Three-dimensional Structures of Fibrillar Sm Proteins: Hfq and Other Sm-like Proteins." Journal of Molecular Biology 356, no. 1 (February 2006): 86–96. http://dx.doi.org/10.1016/j.jmb.2005.11.010.

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Blum, Werner F., Michael B. Ranke, and Jürgen R. Bierich. "Isolation and partial characterization of six somatomedin-like peptides from human plasma Cohn fraction IV." Acta Endocrinologica 111, no. 2 (February 1986): 271–84. http://dx.doi.org/10.1530/acta.0.1110271.

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Abstract. Six somatomedin-like peptides were purified from human plasma Cohn fraction IV by a six-step procedure which included ethanol precipitation, reversed-phase extraction, gel filtration, chromatofocusing and reversed-phase high pressure liquid chromatography (HPLC). Purification was monitored with a competitive protein binding assay using a crude preparations of somatomedin carrier protein. The peptides isolated were homogeneous by reversed-phase HPLC and sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE). Their apparent isoelectric points determined by chromatofocusing were 9.2 (Sm I), (Sm II), 8.2 (Sm III), 6.7 (Sm IV), 6.3 (Sm V), and 6.15 (Sm VI). SDS-PAGE under reducing conditions revealed that they are composed of a single peptide chain with apparent molecular weights of 6800 for Sm I, II and IV and 6400 for Sm III, V, and VI. They were equally potent in the porcine costal cartilage in vitro bioassay. The basic peptides (Sm I–III) were significantly more active in radioimmunoassays for somatomedin C (SmC) and insulin-like growth factor I C-peptide (IGF-I (30–41)), while only the slightly acidic peptides were active in a radioimmunoassay for insulin-like growth factor II C-peptide (IGF-II (33–40)). When receptor binding was tested with human placental cell membranes and Sm III as tracer, the basic peptides were significantly more potent than Sm IV–VI. With rat liver cell membranes and Sm V as tracer the slightly acidic peptides were more potent. These findings suggest 1) that human plasma may contain other somatomedin-like peptides besides the major components IGF-I/SmC and IGF-II, and 2) that the basic peptides are structurally related to IGF-I/SmC and the slightly acidic peptides are related to IGF-II.
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Cenci, Luca, Luca Pulvirenti, Giorgio Boni, and Nazzareno Pierdicca. "Defining a Trade-off Between Spatial and Temporal Resolution of a Geosynchronous SAR Mission for Soil Moisture Monitoring." Remote Sensing 10, no. 12 (December 4, 2018): 1950. http://dx.doi.org/10.3390/rs10121950.

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The next generation of synthetic aperture radar (SAR) systems could foresee satellite missions based on a geosynchronous orbit (GEO SAR). These systems are able to provide radar images with an unprecedented combination of spatial (≤1 km) and temporal (≤12 h) resolutions. This paper investigates the GEO SAR potentialities for soil moisture (SM) mapping finalized to hydrological applications, and defines the best compromise, in terms of image spatio-temporal resolution, for SM monitoring. A synthetic soil moisture–data assimilation (SM-DA) experiment was thus set up to evaluate the impact of the hydrological assimilation of different GEO SAR-like SM products, characterized by diverse spatio-temporal resolutions. The experiment was also designed to understand if GEO SAR-like SM maps could provide an added value with respect to SM products retrieved from SAR images acquired from satellites flying on a quasi-polar orbit, like Sentinel-1 (POLAR SAR). Findings showed that GEO SAR systems provide a valuable contribution for hydrological applications, especially if the possibility to generate many sub-daily observations is sacrificed in favor of higher spatial resolution. In the experiment, it was found that the assimilation of two GEO SAR-like observations a day, with a spatial resolution of 100 m, maximized the performances of the hydrological predictions, for both streamflow and SM state forecasts. Such improvements of the model performances were found to be 45% higher than the ones obtained by assimilating POLAR SAR-like SM maps.
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Urban, S., H. Kresse, and R. Dąbrowski. "Low Frequency Dielectric Relaxation Process in Liquid Crystals with Nematic and Liquid-Like Smectic Phases." Zeitschrift für Naturforschung A 52, no. 5 (May 1, 1997): 403–8. http://dx.doi.org/10.1515/zna-1997-0505.

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Abstract Results of dielectric studies of the low frequency relaxation process in several substances exhibiting nematic -smectic C polymorphism are presented. They are compared with the data obtained re-cently for substances with nematic-smectic A and nematic-smectic B phase sequences. It was found that the rate of molecular reorientation around the short axes does not change at the transition between the nematic and a liquid-like smectic phase (Sm A, Sm C), whereas it is considerably retarded at that of the nematic-solid-like smectic (Sm B) phase. However, the activation barrier for this motion is markedly lower in the orthogonal smectics (Sm A, Sm B) than in the nematic and Sm C phases. The analysis of numerous experimental data on the activation enthalpy in the nematic phase shows that the Arrhenius equation conforms better with results than the Diogo-Martins approach, if the nematic range exceeds 10 K.
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Smith, E. P., T. W. Sadler, and A. J. D'Ercole. "Somatomedins/insulin-like growth factors, their receptors and binding proteins are present during mouse embryogenesis." Development 101, no. 1 (September 1, 1987): 73–82. http://dx.doi.org/10.1242/dev.101.1.73.

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Somatomedins/insulin-like growth factors (Sm/IGFs) are considered to have important roles in regulating fetal growth; however, because of limited quantities of tissue, few studies have been performed on their effects on embryonic growth. To assess a potential role for these factors, we evaluated mouse embryonic tissues for the presence of Sm/IGF and insulin receptors and Sm/IGF-binding proteins by chemical affinity labelling. In addition, we measured extractable Sm-C/IGF-I radioimmunoactivity in mouse embryonic tissues. Finally, we compared these data with those from the embryonal carcinoma cell line, PC13. All embryos from day 9 (3–4 somites) to day 12 (45 somites) possessed both Sm-C/IGF-I and IGF-II receptors in apparent greater abundance than insulin receptors. The visceral yolk sac appeared to have proportionally more insulin receptors than the corresponding embryonic tissue. Extracts from the embryos contained immunoreactive Sm-C/IGF-I and binding proteins of 30–45 X 10(3) Mr. PC13 cells possessed all three receptors and the apparent abundance of the insulin and IGF-II receptors was reduced after differentiation was induced with retinoic acid. PC13 cells released both immunoreactive Sm-C/IGF-I- and Sm-C/IGF-I-binding proteins into their medium. When differentiated, the binding proteins resembled the native ones extracted from the intact embryos. The presence of Sm/IGF activity, receptors and binding proteins in early embryogenesis suggests a role for these factors in embryonic growth. The PC13 cell line appears to only partially reflect normal development.
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Singhal, Jai Kumar, Sardar Singh, and Ashok K. Nagawat. "Distinguishing a SM-like MSSM Higgs boson from SM Higgs boson at muon collider." Pramana 68, no. 6 (June 2007): 931–41. http://dx.doi.org/10.1007/s12043-007-0093-6.

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Salgado-Garrido, J. "Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin." EMBO Journal 18, no. 12 (June 15, 1999): 3451–62. http://dx.doi.org/10.1093/emboj/18.12.3451.

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Blum, Werner F., Michael B. Ranke, Brigitte Lechner, and Jürgen R. Bierich. "The polymorphic pattern of somatomedins during human development." Acta Endocrinologica 116, no. 4 (December 1987): 445–51. http://dx.doi.org/10.1530/acta.0.1160445.

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Abstract. Human somatomedins (Sm) are heterogeneous on separation by chromatofocussing. Besides the 'classic' insulin-like growth factor I and II (IGF-I/Sm-C and IGF-II), a number of minor peaks emerge which can be classified as IGF-I/Sm-C-like or as IGF-II-like. The aim of the current study was to investigate whether or not polymorphism of somatomedins is present in individuals and whether or not the polymorphic pattern changes during development. Serum extracts from normal healthy children and adults were fractionated by chromatofocussing and the various somatomedin-like peptides were quantitated by specific radioimmunoassays for IGF-I/Sm-C or IGF-II. The results demonstrate 1) that heterogeneity of somatomedins is a common phenomenon existing in all individuals studied, and 2) that the polymorphic patterns of the IGF-I/Sm-C-family and of the IGF-II-family remain rather stable during development, although minor changes are evident.
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Guchait, Monoranjan, and Jacky Kumar. "Light Higgs bosons in NMSSM at the LHC." International Journal of Modern Physics A 31, no. 12 (April 28, 2016): 1650069. http://dx.doi.org/10.1142/s0217751x1650069x.

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The next-to-minimal supersymmetric Standard Model (NMSSM) with an extended Higgs sector offers at least one Higgs boson as the Standard Model (SM)-like Higgs with a mass around 125 GeV. In this work, we revisit the mass spectrum and couplings of non-SM-like Higgs bosons taking into consideration most relevant constraints and identify the relevant parameter space. The discovery potential of these non-SM-like Higgs bosons, apart from their masses, is guided by their couplings with gauge bosons and fermions which are very much parameter space sensitive. We evaluate the rates of productions of these non-SM-like Higgs bosons at the LHC for a variety of decay channels in the allowed region of the parameter space. Although [Formula: see text], [Formula: see text] modes appear to be the most promising decay channels, but for a substantial region of parameter space the two-photon decay mode has a remarkably large rate. In this study we emphasize that this diphoton mode can be exploited to find the non-SM-like Higgs bosons of the NMSSM and can also be a potential avenue to distinguish the NMSSM from the MSSM. In addition, we discuss briefly the various detectable signals of these non-SM Higgs bosons at the LHC.
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Cao, Bao Wei, and Yun Hua Xu. "Simulated Sun-Light-Driven Degradation of Rhodamine B by Porous Peanut-like Sm-Doped BiVO4 Sub-Microstructures." Applied Mechanics and Materials 423-426 (September 2013): 20–23. http://dx.doi.org/10.4028/www.scientific.net/amm.423-426.20.

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Porous peanut-like Sm-doped BiVO4 sub-microstructures were synthesized via a hydrothermal process with bismuth nitrate, ammonium metavanadate and Sm (NO3)3 as raw materials. The crystal structures, morphologies, and optical properties of the as-prepared samples were characterized by X-ray powder diffraction, transmission electron microscope, scanning electron microscopy, and UV-visible absorption spectra. Simulated solar light induced photocatalytic degradation of Rhodamine B by porous peanut-like Sm-doped BiVO4 sub-microstructures have been investigated, and results show the 2% Sm-doped BiVO4 porous sub-microstructures with higher photocatalytic activity than other samples.
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Dissertations / Theses on the topic "Sm like"

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He, Weihai. "SM-like proteins function in mRNA degradation of Saccharomyces cerevisiae." Diss., The University of Arizona, 2001. http://hdl.handle.net/10150/279964.

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The degradation of mRNA is a critical step in determining the regulation and levels of gene expression. A family of Sm-Like (Lsm) proteins containing the "Sm" sequence motif has been identified, which forms a complex with U6 snRNA and functions in pre-mRNA splicing. Moreover, Lsm proteins interact with mRNA decay factors in yeast two-hybrid analysis. One of the Lsm proteins, Lsm1p, is required for the efficient decapping of mRNA during degradation. Lsm proteins might exist as a complex since they coimmunoprecipitate with each other. Based on these observations we hypothesized that the family of Lsm proteins might be involved in mRNA degradation. We showed that mutations in seven Lsm proteins (Lsm1-Lsm7) caused inhibition of decapping. These Lsm proteins co-immunoprecipitated with Dcp1p (the decapping enzyme), Pat1p (a decapping activator) and with mRNA, indicating that the Lsm proteins (Lsm1--Lsm7) play a direct role in promoting the decapping step of mRNA degradation. In addition, the Lsm proteins seem to form distinct complexes that affect different aspects of mRNA metabolism. A nuclear Lsm complex consisting of Lsm2p through Lsm8p, interacts with U6 snRNA and promotes pre-mRNA splicing. A cytoplasmic Lsm complex consisting of Lsm1p through Lsm7p binds mRNA and functions in mRNA degradation. The cytoplasmic Lsm complex plays a second role in protecting the 3 ' UTR of mRNA from trimming. Mutations in the cytoplasmic Lsm complex caused trimming of mRNAs. The ski mutations, which cause defects in 3' to 5' mRNA degradation suppressed the temperature-sensitive growth of lsm mutants by preventing the further degradation of trimmed mRNAs. These results argue that Lsm complex might bind to the 3' UTR of mRNAs and protect it from trimming. In addition, the 3' to 5 ' degradation of the trimmed mRNAs might at least in part account for the temperature-sensitive growth of the lsm and the pat1 mutants.
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Mayes, Andrew Easson. "Identification and characterisation of proteins interacting with Uss1p : a Saccharomyces cerevisiae Sm-like protein." Thesis, University of Edinburgh, 1998. http://hdl.handle.net/1842/15298.

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The seven canonical Sm proteins of Saccharomyces cerevisiae associate with the U1, U2, U4 and U5 spliceosomal snRNAs, and have roles in the biogenesis and localisation of these snRNP particles. The proteins interact extensively with one another in an ordered pathway. In contrast, the Uss1 protein is a non-canonical member of the Sm-like protein family in that it associates with the U6 snRNA. A combination of molecular genetic and biochemical analysis has been used to investigate the molecular associations of the Uss1 protein. Exhaustive two-hybrid screens revealed interactions with other Sm-like proteins, with proteins of the U2 snRNP (and proteins interacting with U2 snRNP proteins) and with proteins not previously reported to be involved in pre-mRNA splicing. A network of potential interactions was produced from these data. Deletion of six open reading frames (ORFs) encoding Sm-like proteins revealed three as essential for cell viability (YBL026w, YER146w and USS2) and three as non-essential (SPB8, YDR378c and YNL147w) suggesting functional redundancies within these non-canonical Sm-like proteins. Since significant levels of U6 snRNA can be precipitated with all 6 proteins, and the Yjr022p (an Sm-like protein identified in two-hybrid screens) the genes encoding these proteins were added to the USS (U-Six SnRNP) gene class. A subset of these proteins is essential for the stability of U6 snRNA in vivo, with over-production of U6 capable of (partially) rescuing the growth of the conditional strains. All 7 Sm-like proteins which associate with U6 snRNA also co-immunoprecipitate with Uss1p. This combined with the range of interactions revealed by two-hybrid analyses suggests the existence of an Sm-like protein complex (or complexes).
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Setzer, Katharine Adrienne. "Playing on-line : sexual subjectivity, gender play and the construction of the dyke SM fantasy." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ54267.pdf.

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Avand-faghih, Arman. "Identification et Application Agronomique de Synergistes Végétaux de la Phéromone du Charançon Rhynchophorus ferrugineus (Olivier) 1790." Phd thesis, INAPG (AgroParisTech), 2004. http://pastel.archives-ouvertes.fr/pastel-00000692.

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RÉSUMÉ: Le charançon rouge des palmiers, Rhynchophorus ferrugineus (Oliv.), est l'insecte ravageur le plus destructif des palmiers cultivés en Asie, Moyen-Orient et bassin méditerranéen. Le piégeage olfactif peut jouer un rôle important en lutte intégrée contre ce ravageur mais l'usage indispensable de matériel végétal comme synergiste de sa phéromone d'agrégation limite son efficacité et son essor en zone désertique. Afin de disposer d'un synergiste synthéti-que de la phéromone, nous avons criblé par piégeage de terrain en Iran l'effet synergique avec la phéromone de molé-cules identifiées dans: 1- l'odeur de stipe de dattier, la plante-hôte de R. ferrugineus au Moyen-Orient lors de ce travail et 2- d'autres plantes-hôtes de Rhynchophorus spp. et décrites dans la bibliographie ou de structure apparentée. Nous avons utilisé la chromatographie en phase gazeuse (CPG) couplée à la spectrométrie de masse pour identifier la compo-sition d'odeurs de stipe de dattier isolées par collecte d'effluves. Les constituants potentiellement actifs sur le compor-tement de l'insecte ont été criblés par couplage CPG-électroantennographie (CPG-EAG) après une étude morphofonc-tionnelle de l'antenne par microscopie électronique à balayage et électroantennographie visant à vérifier s'il existait une régionalisation olfactive de la massue antennaire. Quatre types majoritaires de soies ont été identifiés, similaires à ceux décrits chez Rhynchophorus palmarum. Deux correspondent à des sensilles olfactives trichoïdes et basiconiques. La densité de sensilles basiconiques est plus élevée chez les femelles que chez les mâles et, chez les deux sexes, sur la face interne de la massue que sur la face externe. Les amplitudes des électroantennogrammes enregistrés à six molécules odorantes sont plus fortes à partir de la face interne de l'antenne que de la face externe mais le même profil de réponse a été obtenu que le branchement ait été réalisé en position, dorsale, centrale ou ventrale sur la massue. Au total, 109 molécules ont été identifiées dans les extraits d'odeur de dattier. Dix produits ont induit des électroantennogrammes reproductibles dans les analyses CPG-EAG dont un, l'anisole, a été identifié. L'effet phérosynergique de deux mélanges élaborés à partir des analyses d'odeurs de dattier, d'un mélange de molécules déclenchant des EAG de fortes amplitudes et de 21 mélanges bâtis à partir de 52 molécules issues de la bibliographie ont été étudiés. Parmi tous les mélanges testés sur le terrain, un mélange d'éthanol et d'acétate d'éthyle (50:50 v/v) à une dose de 300 mg/j a présenté un effet phérosynergique compétitif avec 0,35 kg de stipe de dattier et parfois avec 1,2 kg. Une variabilité importante de l'effet relatif entre ce mélange et le tissu de dattier a été observé au cours des trois saisons de travail. Aucun des mélanges plus complexes évalués n'a présenté d'effet notablement supérieur. L'activité antennaire de produits non identifiés dans l'odeur naturelle de dattier et l'absence d'effet phérosynergique des molécules testées, compétitif avec l'odeur naturelle, mettent en évidence le rôle important de composants de l'odeur du dattier non identifiés et/ou l'existence d'effets de mélange non évalués lors du présent travail. Le mélange d'éthanol et d'acétate d'éthyle, simple et bon marché, offre néanmoins une alternative intéressante pour améliorer le piégeage olfactif de R. ferrugineus dans la pratique, compte tenu du statut actuel de ce ravageur et de l'absence de meilleure alternative à l'usage d'appâts naturels.
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Peltre, Clément. "Potentialité de stockage de carbone dans les sols par apport de matières organiques exogènes." Phd thesis, AgroParisTech, 2010. http://pastel.archives-ouvertes.fr/pastel-00602825.

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L'apport aux sols de matières organiques exogènes (MOEs) d'origine résiduaire issues d'activités agricoles, urbaines ou industrielles permet d'augmenter les teneurs en matière organique des sols (MOS) et d'améliorer leur fertilité. De plus ces apports de MOEs pourraient contribuer à la limitation des émissions nettes de gaz à effet de serre en stockant du C dans les sols. Le développement d'outils de prédiction est nécessaire pour une meilleure estimation du devenir à long terme des MOEs apportées. De plus, il est important de savoir sous quelles formes la matière organique (MO) des MOEs est incorporée dans la MO du sol, ceci conditionnant la pérennité des accumulations de C après apports répétés de MOEs. Cette étude vise à mieux comprendre et prédire la dynamique d'incorporation de la MO de matières organiques exogènes dans la matière organique du sol. Elle s'est déroulée en trois étapes : (i), le développement et l'amélioration de méthodes de caractérisation de laboratoire permettant d'estimer le devenir des MOEs dans le sol (ii) le paramétrage du modèle RothC pour simuler l'accumulation de C dans les sols suite à l'apport de MOEs et (iii) l'étude des changements de composition chimique de la MOS suite à des apports répétés de MOEs.
L'étude de la composition chimique de la fraction dite soluble du fractionnement biochimique Van Soest a révélé que la nature chimique de cette fraction de MO change lors du traitement par compostage des MOEs: elle est très riche en polysaccharides en début de compostage et s'enrichit en MO riche en composés azotés stabilisés au cours du compostage.
Le potentiel d'utilisation de la spectroscopie proche infra-rouge (SPIR) pour caractériser les MOEs et leur devenir dans le sol a été étudié. Des prédictions satisfaisantes ont été obtenues pour les teneurs en C et N des MOEs ainsi que pour les fractions biochimiques Van Soest des MOEs. L'indicateur de stabilité de la MO (ISMO), estimateur de la fraction résiduelle de la MO des MOEs à long terme dans les sols, a été prédit de manière satisfaisante.
La potentialité de stockage de C à long terme dans un sol soumis à des apports répétés de MOEs a été étudiée en utilisant des résultats de 4 essais au champ de moyenne et longue durées. les apports répétés de MOEs ont entrainé des augmentations significatives des stocks de C dans les sols qui ont pu être reproduites de façon satisfaisante avec le modèle RothC qui a été ainsi paramétrés pour pouvoir simuler des apports de MOEs de types divers.
L'étude des changements dans la composition de la MOS suite à ces apports répétés de MOEs dans l'essai Qualiagro a révélé une modification préférentielle de la fraction de MOS particulaire de taille > 50 µm, en particulier par un enrichissement en lignine. La composition de la fraction de taille 0-50 µm est également modifiée mais dans une moindre mesure et de façon moins directement liée à la composition des MOEs apportées.
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Sivadier, Guilhem. "Authentification de l'alimentation des ruminants par analyse des composés volatils de leur tissus adipeux." Phd thesis, Université Blaise Pascal - Clermont-Ferrand II, 2008. http://tel.archives-ouvertes.fr/tel-00731275.

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Il existe une forte demande sociétale de moyens analytiques robustes permettant d'authentifier de manière objective les modes d'élaboration des produits alimentaires, notamment lorsqu'ils sont d'origine animale. L'objectif de cette thèse était de développer une méthode d'authentification de l'alimentation à l'herbe des agneaux, basée sur l'analyse de la fraction volatile de leurs tissus adipeux. Les animaux étudiés ont été élevés dans le cadre de dispositifs expérimentaux, où leur alimentation était étroitement contrôlée. Le tissus périnéal, sous-cutané caudal, et péricardiaque ont été analysés au moyen d'un système d'Espace de Tête Dynamique-Chromatographie en Phase Gazeuse- Spectrométrie de Masse (ETD-CPG-SM), dont le signal a été corrigé et stabilisé par différentes procédures chimiométriques. La première étape de ce travail de recherche visait à identifier les traceurs distinctifs de tissus adipeux d'agneaux nourris soit à l'herbe soit aux concentrés. Une fois les conditions d'analyse des composés volatils optimisés,126 traceurs de l'alimentation au pâturage ont été identifiés. Cette expérimentation a également permis de montrer l'intérêt de l'analyse parallèle de tissus de natures différentes pour la discrimination des deux alimentations. La deuxième étape avait pour objectif de montrer l'intérêt de l'analyse de la fraction volatile de tissus adipeux d'agneau pour l'authentification des régimes alternés. Ces régimes, couramment utilisés pour l'élevage des ruminants consistent à alterner une période d'alimentation au pâturage avec une finition aux concentrés, ou inversement. Les variations des abondances des traceurs volatils d'une alimentation au pâturage ont été suivies dans les tissus adipeux d'animaux nourris avec ces régimes alternés. Les résultats montrent que les composés volatils permettent de discriminer des tissus adipeux d'animaux nourris d'une part à l'herbe et finis aux concentrés pour un engraissement final de 0, 4, 8, ou 12 kg ; et d'autre part aux concentrés et finis au pâturage durant 0,17, 51, ou 85 jours. Couplés aux données de la littérature, l'ensemble des dispositifs d'élevage mis en oeuvre au cours de cette thèse ont permis de mettre en évidence 19 composés volatils traceurs de l'alimentation à l'herbe particulièrement robustes et génériques. Ces travaux démontrent aussi la faisabilité de l'authentification de l'alimentation d'animaux nourris au moyen de régimes contrastés ou alternés. Enfin, ils confirment aussi l'intérêt des procédures de traitement du signal, comme la correction des dérives instrumentales ou l'utilisation de ratios de variables, pour amplifier le pouvoir discriminant des modèles d'authentification.
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Lin, Yi-Chuen, and 林詣淳. "Search for SM-like Higgs in the UMSSM." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/60100797793319703828.

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Jerhot, Jan. "Search for Axion-Like Particles at the NA62 experiment." Master's thesis, 2019. http://www.nusl.cz/ntk/nusl-397715.

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The thesis instructively presents axions and axion-like particles as a plau- sible extension of the Standard Model of particle physics and discusses also the cosmological implications in the case of their existence as they present one of the most favourable dark matter candidates at given circumstances. The main part of the thesis is concerned with a search for axion-like particles at the NA62 experiment at CERN and a study of the gathered data and its impact on the data analysis.
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Bonneville, Lourenço Maria Corrêa Monteiro Cayolla. "Characterization of biofilm formation by Clostridioides difficile." Master's thesis, 2022. http://hdl.handle.net/10362/133789.

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Clostridioides difficile is an urgent threat level enteric pathogen, that can produce endospores, toxins and biofilms. This work focused on understanding the regulatory circuits controlling gene expression during biofilm formation in C. difficile. We characterized the Veg protein, a highly conserved protein among Gram-positive bacteria, and that in B. subtilis was shown to stimulate biofilm formation by inducing biofilm-specific gene expression. Veg, is a 10 kDa, Sm-like protein. Sm proteins form multimers that bind to RNA. We show that overproduction of Veg also stimulated biofilm formation in a C. difficile lab strain. In vitro the oligomeric state of Veg is pH-dependent and shifts the protein from monomer to dimer and higher order protein complexes. We have no evidence for binding to RNA but we show that Veg binds to DNA, specifically to a TA rich region in the cdeM promotor. cdeM is a late sporulation gene involved in assembly of the spore surface layers and whose expression is dependent on yabG, the gene adjacent to veg, coding for a cysteine protease. We propose a model of repression of cdeM by Veg, that could be lifted by proteolysis of Veg by YabG.
Clostridioides difficile é um patogéneo entérico humano, de grande importância médica e económica, com capacidade de produzir endósporos, toxinas e biofilmes. O presente trabalho focou-se na compreensão dos circuitos regulatórios que controlam a expressão genética durante a formação de biofilme em C. difficile. Em particular, procedemos à caracterização de Veg, uma proteína conservada em bactérias Gram-positivas, que, em B. subtilis, induz a expressão de genes específicos para a formação de biofilme e estimula a produção destas estruturas. Veg é uma proteína de 10 kDa com um domínio Sm, característico de proteínas que formam oligomeros e ligam RNA. Neste trabalho demonstramos que a sobreprodução de Veg estimula a produção de biofilme numa estirpe de laboratório de C. difficile. In vitro, Veg existe maioritariamente como um monómero a pH igual ou inferir ao pI, e como um dímero e formas de elevado peso molecular acima do pI. Apesar de não termos evidência de uma interação com RNA, demonstramos que Veg liga a DNA, especificamente a regiões ricas em AT no promotor cdeM. O gene cdeM é transcrito em fases tardias da esporulação, na célula mãe, e é essencial para a montagem da superfície do esporo. A expressão de cdeM é dependente de yabG. Por sua vez, ivabG, imediatamente a montante de veg, codifica para uma protéase de cisteína. Propomos um modelo de repressão de cdeM por Veg, que pode ser levantada através de proteólise de Veg por YabG.
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Badouard, Carine. "Les lésions des acides nucléiques: détection par CLHP-SM/SM dans les milieux biologiques humains et intérêt comme biomarqueurs du stress oxydant et de l'inflammation." Phd thesis, 2006. http://tel.archives-ouvertes.fr/tel-00134563.

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L'ADN ou l'ARN, détenteurs de l'information génétique, peuvent subir des dommages dus aux acteurs du stress oxydant ou de l'inflammation. La cellule a développé des mécanismes de réparation de ces dommages, mais certaines lésions peuvent persister et devenir mutagènes. Dans ce but, nous nous sommes intéressés au dosage simultané de plusieurs de ces lésions à l'aide d'une technique de chromatographie liquide couplée à un spectromètre de masse en mode tandem, outil analytique rapide et fiable ayant une très grande sensibilité. Le but de ce travail était de trouver des biomarqueurs du stress oxydant ou de l'inflammation parmi les lésions connues de l'ADN et de les quantifier dans les milieux biologiques humains afin de compléter le panel existant de biomarqueurs protéiques ou lipidiques. Ainsi, trois groupes de lésions ont pu être quantifiés : les lésions oxydatives issues de l'action des espèces oxygénées activées, les lésions chlorées issues des phénomènes inflammatoires et les adduits de la peroxydation lipidique. Les étapes de mise au point analytique ayant été optimisées, elles ont été suivies d'une validation biologique parmi différentes pathologies étudiées et représentées par le diabète, certains cancers traités par radiothérapie et les hommes atteints d'infertilité masculine. Les différents résultats montrent une variation des taux des certaines lésions dans les leucocytes circulants ou des l'urine des patients par rapport aux sujets sains. Néanmoins, ces essais nécessitent d'être confirmés quant à l'utilisation des ces lésions en tant que biomarqueurs. D'autres types de pathologies devront également être testés.
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Books on the topic "Sm like"

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Diedericks, André. Journey without boundaries: The operational life and experiences of a SA Special Forces small team operator : the personal memoirs of Colonel André Diedericks HCS, HC, SM, MMM. Durban: Just Done Productions Publishing, 2007.

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Books, Golden. SM Like Stars \Mile 1. Golden books, 1998.

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Books, Golden. I Like Me Lk Lk SM PP. Golden books, 1997.

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Audesirk. Sm Life Earth Tif. Prentice Hall, 1996.

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Staff, Barnett Ziegler. Sm Calulus Business Econ Life. Pearson Education, Limited, 1999.

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Barnett. Sm Applied Math Bus Econ Life. Macmillan Library Reference, 1986.

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Sm Biol Life Earth Audesirk in. Prentice Hall, 1998.

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Barnett & Ziegler. Sm College Maths Bus Econ Life. Prentice Hall, 1998.

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Audesirk. Sm Life Earth Windows Cd-Rom. Pearson Education, Limited, 1997.

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Barnett. Sm Applied Math Bus Econ Life. Macmillan Library Reference, 1994.

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Book chapters on the topic "Sm like"

1

Valentin-Hansen, Poul. "Structure, Function and RNA Binding Mechanisms of the Prokaryotic Sm-like Protein Hfq." In Regulatory RNAs in Prokaryotes, 147–62. Vienna: Springer Vienna, 2012. http://dx.doi.org/10.1007/978-3-7091-0218-3_8.

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Kushan, S. R., N. C. Acikbas, J. Křest'an, Pavol Šajgalík, and Hasan Mandal. "Role of α-SiAlON Nuclei Addition on the Rod-Like Y-Sm α-SiAlON Formation." In Materials Science Forum, 101–6. Stafa: Trans Tech Publications Ltd., 2007. http://dx.doi.org/10.4028/0-87849-439-1.101.

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Caillol, Cécile. "Search for Exotic Decays of the SM-Like Scalar Boson in the $$\mu \mu \tau \tau $$ μ μ τ τ Final State." In Springer Theses, 185–215. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-70650-4_11.

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Lent, Bogdan. "04:00 Self Management (Work & Life Balance): SM." In Cybernetic Approach to Project Management, 365–98. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-32504-5_18.

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Basumatary, Himalay, J. Arout Chelvane, Vajinder Singh, and Rajeev Ranjan. "Microscopic and Magnetic Investigations in Sputtered Sm-Fe Thin Films." In Applications of Microscopy in Materials and Life Sciences, 171–80. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-2982-2_17.

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Gonsalvez, Graydon B., and A. Gregory Matera. "Posttranslational Modification of Sm Proteins: Diverse Roles in snRNP Assembly and Germ Line Specification." In Posttranscriptional Gene Regulation, 83–116. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527665433.ch4.

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Wu, Jiang, Qing Wang, Yan Hui Li, Jian Bing Qiang, Ying Min Wang, and Chuang Dong. "Ternary Sm-Al-Co Bulk Metallic Glass Formation Designed Using a Cluster Line Approach." In Materials Science Forum, 1267–70. Stafa: Trans Tech Publications Ltd., 2007. http://dx.doi.org/10.4028/0-87849-462-6.1267.

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McGrath, Jillian L., and Lydia M. Sahlani. "Like, Comment, Post . . . Lawsuit?!" In Legal and Ethical Issues in Emergency Medicine, 169–74. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780190066420.003.0023.

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Social media (SM) and electronic communication (EC) use in emergency practice settings has offered patients and health care providers expansive options in accessing and utilizing information that affects medical decision-making. This widespread use has created opportunities and challenges for the health care community. This chapter discusses some of the ethical and legal ramifications of utilizing electronic communication, social media, and internet forums in patient care. The chapter seeks to prime emergency physicians and other providers to better inform themselves in order to ensure compliance with the Health Insurance Portability and Accountability Act (HIPAA) and other privacy standards. This will facilitate better patient outcomes via collaborative diagnosis while protecting against legal risks associated with the use of SM, EC, and recording for medical purposes.
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"what do sm dykes wear to work?" In What is She Like? Bloomsbury Academic, 2016. http://dx.doi.org/10.5040/9781474292498.ch-006.

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Zinn-Justin, Jean. "The Standard Model (SM) of fundamental interactions." In Quantum Field Theory and Critical Phenomena, 567–92. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780198834625.003.0023.

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The Standard Model (SM) 2020 of weak, electromagnetic and strong interactions, based on gauge symmetry and spontaneous symmetry breaking, describes all known fundamental interactions at the microscopic scale except gravity and, perhaps, interactions with dark matter. The SM model has been tested systematically in collider experiments, and in the case of strong interactions (quantum chromodynamics) also with numerical simulations. With the discovery in 2012 of the Higgs particle at the Large Hadron Collider (LHC) at the European Council for Nuclear Research (CERN), all particles of the SM have been identified, and most parameters have been measured. Still, the Higgs particle remains the most mysterious particle of the SM, since it is responsible for all the parameters of the SM except gauge couplings and since it leads to the fine-tuning problem. The discovery of its origin, and the precise study of its properties should be, in the future, one of the most important field of research in particle physics. Since we know now that the neutrinos have masses, the simplest extension of the SM implies Dirac neutrinos. With such a minimal modification, consistent so far (2020) with experimental data, the lepton and quark sectors have analogous structures: the lepton sector involves a mixing matrix, like the quark sector (three angles have been determined, the fourth charge conjugation parity (CP) violating angle is still unknown).
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Conference papers on the topic "Sm like"

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Berglof, W. R., K. Krainer, and S. G. Lucas. "TEPEE-LIKE STRUCTURES IN THE MIDDLE JURASSIC TODILTO FORMATION, WESTCENTRAL NEW MEXICO." In 2009 New Mexico Geological Society Annual Spring Meeting. Socorro, NM: New Mexico Geological Society, 2009. http://dx.doi.org/10.56577/sm-2009.667.

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Bai-shun Liu, Bing-Li Tian, and Fan-Cai Lin. "A class of globally stable SM-NPID-like tracking controllers for robotic manipulators." In 2010 3rd IEEE International Conference on Computer Science and Information Technology (ICCSIT 2010). IEEE, 2010. http://dx.doi.org/10.1109/iccsit.2010.5564596.

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Suazo, Thomas Lee, Amanda Kaye Cantrell, and Spencer G. Lucas. "Preliminary Description of an Ianthasaurus-like Edaphosaurid From the Lower Permian Bursum Formation, Otero County, New Mexico." In 2015 New Mexico Geological Society Annual Spring Meeting. Socorro, NM: New Mexico Geological Society, 2015. http://dx.doi.org/10.56577/sm-2015.369.

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Victoria, Patricia Iglesias, Weimin Yin, Surendra K. Gupta, and Steve Constantinides. "Microstructural Characterization of Sm-Co Magnets." In ASME 2014 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/imece2014-37106.

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Samarium cobalt permanent magnets have been widely used for their excellent intrinsic magnetic properties such as very high Curie temperature, high anisotropy fields and most importantly excellent temperature coefficients of induction and coercivity. These materials have continuing industrial interest especially for applications operating at elevated temperatures and in the presence of high demagnetizing fields, such as particle accelerators, high frequency traveling wave tubes (TWTs), servo-motors and automotive and aerospace applications. An area of opportunity for improving performance of SmCo magnets is increasing magnet toughness — resistance to fracture. Like all other sintered rare earth magnetic materials, SmCo magnets are based on intermetallic compounds which are intrinsically brittle and can crack in the course of fabrication, machine work, and installation in the application. Increased toughness would also reduce handling sensitivity of magnetized magnets. For many years, studies on SmCo magnets have been focused on their magnetic properties, but the mechanical characteristics, strengthening and toughening mechanisms have been rarely reported. Understanding the phase and structural transformations induced in the SmCo magnets during the manufacturing process offers insight into potential modifications — chemical or processing-related. In this study, microstructural characterizations of 1:5 and 2:17 Sm-Co magnets were carried out using optical and scanning electron microscopes. In scanning electron microscopy (SEM), backscattered electron imaging and energy dispersive X-ray (EDX) microanalysis were used to investigate different phases and oxides. Finally, crystal structure of the magnets was studied using an X-ray diffractometer (XRD). The study correlates the microstructure characterization with the thermal processing history of different grades of SmCo magnets.
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Haber, Howard. "A natural mechanism for a SM-like Higgs boson in the 2HDM without decoupling." In 7th Symposium on Prospects in the Physics of Discrete Symmetries, DISCRETE 2020-2021. Trieste, Italy: Sissa Medialab, 2022. http://dx.doi.org/10.22323/1.405.0010.

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Green, Deborah. "You Don’t Look Like a Geologist – A Conversation on Diversity (or the Lack Thereof) in Our Profession." In 2021 New Mexico Geological Society Annual Spring Meeting. Socorro, NM: New Mexico Geological Society, 2021. http://dx.doi.org/10.56577/sm-2021.2779.

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Orduz, Javier. "The Machine Learning role in High Energy Physics." In LatinX in AI at Neural Information Processing Systems Conference 2018. Journal of LatinX in AI Research, 2018. http://dx.doi.org/10.52591/lxai2018120321.

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We explore some Standard Model (SM) extensions considering Machine Learning (ML) techniques. This is stage one, looking for recents papers, collaborations and events to build the framework and the contributions in this exciting field which combines: Physics, Computing, Mathematics and Artificial Intelligence. Our main expectations (stage two of the project) are to explore some of the new physics scenarios such as THDM, gauge extended models and vector-like models, and we investigate the observables and parameters using some ML techniques to place some bounds and define exclusion regions for the models. These techniques could prove to be useful in the understanding of flavor-changing scalar interactions, the detection of new particles and precise measurements of SM particles.
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Little, Elizabeth C., E. Ramsay Camp, Cindy Wang, Patricia M. Watson, Dennis K. Watson, and David J. Cole. "Abstract A48: The role of the cancer-associated Sm-like oncogene in development of pancreatic cancer." In Abstracts: AACR Special Conference on Pancreatic Cancer: Progress and Challenges; June 18-21, 2012; Lake Tahoe, NV. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.panca2012-a48.

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Liu, Bai-shun, Feng-Lei Ding, and Ying-Ze Hao. "Global Position Tracking of Robot Manipulators via SM-NPID-like Controllers with Two Nonlinear Integral Actions." In 2010 International Conference on Electrical and Control Engineering (ICECE). IEEE, 2010. http://dx.doi.org/10.1109/icece.2010.272.

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MRENNA, S. "THE COMPLEMENTARITY OF THE TEVATRON AND LHC FOR TESTING THE MSSM THROUGH SM-LIKE HIGGS BOSON SEARCHES." In Proceedings of the 7th International Symposium. WORLD SCIENTIFIC, 2000. http://dx.doi.org/10.1142/9789812792433_0010.

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