Academic literature on the topic 'Slitrya'

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Journal articles on the topic "Slitrya"

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Miranda, Débora Marques de, Marco Aurélio Romano Silva, and Antônio Lúcio Teixeira. "Síndrome de Tourette." Revista Neurociências 15, no. 1 (January 23, 2019): 84–87. http://dx.doi.org/10.34024/rnc.2007.v15.8735.

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A Síndrome de Gilles de la Tourette (ST) é uma entidade neuropsiquiátrica caracterizada pela presença de tics e com importante componente hereditário. Muitos grupos vem estudando os aspectos genéticos da ST, mas frequentemente os achados não se sustentam em estudos subsequentes e fica clara toda a dificuldade em estabelecer os genes relacionados com a ST. Entretanto, no último ano foi publicado estudo que correlaciona mutação no gene da Slit and Trk-like family member 1 (SLITRK1) com a presença ST em um pequeno grupo de pacientes. Esse gene codifica a proteína SLITRK1 que é homóloga às proteínas SLIT e o receptor de tirosina cinase (TRK). A família das proteínas SLIT estão envolvidos no direcionamento axonal durante o cruzamento da linha média na medula vertebral. Enquanto o receptor de TRK acelera a diferenciação induzida pelo fator de crescimento neuronal. A SLITRK aparentemente está envolvida no crescimento de dendritos e axônios. Faltam estudos que avaliem a presença de mutações no gene da SLITRK1 em outras populações, assim como que avaliem a possibilidade de alteração de outros genes dessa via de sinalização. Entretanto, caso se confirmem as alterações no gene da SLITRK1, ou de genes correlacionados, o entendimento e o estudo de ST passará a envolver o direcionamento axonal e especialmente as proteínas da via SLITRK-SLIT-ROBO.
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Miranda, Débora Marques de, Marco Aurélio Romano Silva, and Antônio Lúcio Teixeira. "Síndrome de Tourette:." Revista Neurociências 15, no. 1 (October 31, 1999): 84–87. http://dx.doi.org/10.34024/rnc.2007.v15.8737.

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A Síndrome de Gilles de la Tourette (ST) é uma entidade neuropsiquiátrica caracterizada pela presença de tics e com importante componente hereditário. Muitos grupos vem estudando os aspectos genéticos da ST, mas frequentemente os achados não se sustentam em estudos subsequentes e fica clara toda a dificuldade em estabelecer os genes relacionados com a ST. Entretanto, no último ano foi publicado estudo que correlaciona mutação no gene da Slit and Trk-like family member 1 (SLITRK1) com a presença ST em um pequeno grupo de pacientes. Esse gene codifica a proteína SLITRK1 que é homóloga às proteínas SLIT e o receptor de tirosina cinase (TRK). A família das proteínas SLIT estão envolvidos no direcionamento axonal durante o cruzamento da linha média na medula vertebral. Enquanto o receptor de TRK acelera a diferenciação induzida pelo fator de crescimento neuronal. A SLITRK aparentemente está envolvida no crescimento de dendritos e axônios. Faltam estudos que avaliem a presença de mutações no gene da SLITRK1 em outras populações, assim como que avaliem a possibilidade de alteração de outros genes dessa via de sinalização. Entretanto, caso se confirmem as alterações no gene da SLITRK1, ou de genes correlacionados, o entendimento e o estudo de ST passará a envolver o direcionamento axonal e especialmente as proteínas da via SLITRK-SLIT-ROBO.
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Katayama, Kei-ichi, Kazuyuki Yamada, Takashi Inoue, Maya Ota, and Jun Aruga. "Analysis of Slitrk1- and Slitrk2-deficient mice." Neuroscience Research 58 (January 2007): S47. http://dx.doi.org/10.1016/j.neures.2007.06.276.

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Yamazaki, Sho, Kazuki Taoka, Shunya Arai, Masashi Miyauchi, Keisuke Kataoka, Akihide Yoshimi, and Mineo Kurokawa. "Patient-Derived Induced Pluripotent Stem Cells Identified SLITRK4 As a Causative Gene of Chronic Myelomonocytic Leukemia." Blood 128, no. 22 (December 2, 2016): 1134. http://dx.doi.org/10.1182/blood.v128.22.1134.1134.

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Abstract Chronic myelomonocytic leukemia (CMML), the most frequent disease entity of myelodysplastic syndrome/myeloproliferative neoplasm is a clonal hematopoietic malignancy that is characterized by persistent monocytosis, morphologic myeloid dysplasia, and progression to acute myeloid leukemia. The pathogenesis of CMML remains entirely elusive because of the lack of suitable mouse models and the difficulties in the establishment of CMML cell lines. We have previously reported that we established induced pluripotent stem cells (iPSC) from CMML CD34 positive leukemic cells (CMML-iPSC) as a new disease model. Co-cultured with C3H10T1/2 stromal cells in the presence of vascular endothelial growth factor, CMML-iPSC generated CD34 CD43 double-positive hematopoietic progenitor cells (CMML-HPC). CMML-HPC have recapitulated important disease features of parental CMML cells in terms of genetic abnormalities, acceleration of cell proliferation, and aberrant surface markers expression. In addition, a novel human CMML xenograft mouse model has been established through secondary transplantation of human HPCs from CMML-iPSC-derived teratomas. This model produced HPCs that mimicked the properties of CMML in vivo. To identify key molecular abnormalities that contribute to the pathophysiology of CMML, we conducted comprehensive gene expression and DNA methylation profiling analyses of normal and CMML parental CD34 positive cells, iPSC, and their hematopoietic progenies, respectively. Correlation analysis revealed that gene expression and DNA methylation status between normal and CMML iPSC-derived HPC exhibited similar pattern (R2 = 0.92 and 0.96, respectively), although normal and CMML parental CD34 positive cells were quite different (R2 = 0.72 and 0.90, respectively), indicating that reprogramming followed by re-differentiation may enable to obtain more homogenous population of normal and CMML cells that reside in almost the same differentiation stage. These results allowed us to determine the difference in the genetic and epigenetic status between normal and CMML iPSC-derived HPC, which remained through reprogramming and re-differentiation, in order to find out causative genes in the pathogenesis of CMML. Using these combined omics platforms, we identified SLIT and NTRK like family member 4 (SLITRK4) as a candidate gene involving in pathogenesis of CMML, whose expression was enhanced and whose promoters were hypo-methylated in CMML-HPC. In other CMML patients' CD34 positive leukemic cells, the expression of SLITRK4 was up-regulated compared to healthy CD34 positive bone marrow cells and other leukemia cells. In addition, we revealed SLITRK4 had pro-proliferative activity as the knockdown of SLITRK4 inhibited proliferation of leukemic cell lines OCI-AML3. To elucidate whether SLITRK4 exert any biological functions in CMML, we established CMML-iPSC clones harboring hetero-knockout (wt/-) or homo-knockout (-/-) of SLITRK4 gene by CRISPR/Cas9 system. Although SLITRK4 (wt/-) and (-/-) clones did not exhibit any morphological and proliferative difference in CMML-iPSC, the production of HPC from CMML-iPSC was dramatically attenuated in SLITRK4-dependent manner. Therefore, while little has been known about the roles of SLITRK molecules in tumorigenesis, we demonstrated SLITRK4 was indispensable for generation of CMML leukemic cells and suggested the possibility of novel molecular therapy targeting SLITRK4, based on the findings obtained from our combined omics platforms. In summary, we identified SLITRK4 as a novel candidate gene responsible for the pathogenesis of CMML through our combined omics platform using patient-derived iPSC. This platform may provide a potential to trace causative genes in a variety of diseases. Disclosures Kataoka: Kyowa Hakko Kirin: Honoraria; Boehringer Ingelheim: Honoraria; Yakult: Honoraria.
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Salesse, Charleen, Julien Charest, Hélène Doucet-Beaupré, Anne-Marie Castonguay, Simon Labrecque, Paul De Koninck, and Martin Lévesque. "Opposite Control of Excitatory and Inhibitory Synapse Formation by Slitrk2 and Slitrk5 on Dopamine Neurons Modulates Hyperactivity Behavior." Cell Reports 30, no. 7 (February 2020): 2374–86. http://dx.doi.org/10.1016/j.celrep.2020.01.084.

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Urh, Kristian, Margareta Žlajpah, Nina Zidar, and Emanuela Boštjančič. "Identification and Validation of New Cancer Stem Cell-Related Genes and Their Regulatory microRNAs in Colorectal Cancerogenesis." Biomedicines 9, no. 2 (February 11, 2021): 179. http://dx.doi.org/10.3390/biomedicines9020179.

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Significant progress has been made in the last decade in our understanding of the pathogenetic mechanisms of colorectal cancer (CRC). Cancer stem cells (CSC) have gained much attention and are now believed to play a crucial role in the pathogenesis of various cancers, including CRC. In the current study, we validated gene expression of four genes related to CSC, L1TD1, SLITRK6, ST6GALNAC1 and TCEA3, identified in a previous bioinformatics analysis. Using bioinformatics, potential miRNA-target gene correlations were prioritized. In total, 70 formalin-fixed paraffin-embedded biopsy samples from 47 patients with adenoma, adenoma with early carcinoma and CRC without and with lymph node metastases were included. The expression of selected genes and microRNAs (miRNAs) was evaluated using quantitative PCR. Differential expression of all investigated genes and four of six prioritized miRNAs (hsa-miR-199a-3p, hsa-miR-335-5p, hsa-miR-425-5p, hsa-miR-1225-3p, hsa-miR-1233-3p and hsa-miR-1303) was found in at least one group of CRC cancerogenesis. L1TD1, SLITRK6, miR-1233-3p and miR-1225-3p were correlated to the level of malignancy. A negative correlation between miR-199a-3p and its predicted target SLITRK6 was observed, showing potential for further experimental validation in CRC. Our results provide further evidence that CSC-related genes and their regulatory miRNAs are involved in CRC development and progression and suggest that some them, particularly miR-199a-3p and its SLITRK6 target gene, are promising for further validation in CRC.
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Zuchner, S., M. L. Cuccaro, K. N. Tran-Viet, H. Cope, R. R. Krishnan, M. A. Pericak-Vance, H. H. Wright, and A. Ashley-Koch. "SLITRK1 mutations in Trichotillomania." Molecular Psychiatry 11, no. 10 (September 27, 2006): 888–89. http://dx.doi.org/10.1038/sj.mp.4001865.

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Zuchner, S., M. L. Cuccaro, K. N. Tran-Viet, H. Cope, R. R. Krishnan, M. A. Pericak-Vance, H. H. Wright, and A. Ashley-Koch. "SLITRK1 mutations in trichotillomania." Molecular Psychiatry 11, no. 10 (September 27, 2006): 887. http://dx.doi.org/10.1038/sj.mp.4001898.

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Burton, Adrian. "SLITRK1 trouble in Tourette's syndrome." Lancet Neurology 4, no. 12 (December 2005): 801. http://dx.doi.org/10.1016/s1474-4422(05)70242-8.

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Grice, D. E., Y. Kajiwara, T. Sakurai, and J. D. Buxbaum. "Functional dissection of SLITRK1 signaling." European Psychiatry 22 (March 2007): S88. http://dx.doi.org/10.1016/j.eurpsy.2007.01.1201.

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Dissertations / Theses on the topic "Slitrya"

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Charest, Julien. "Mécanismes cellulaires et moléculaires régulés par SLITRK2 et SLITRK5 dans la formation des circuits dopaminergiques du mésencéphale." Master's thesis, Université Laval, 2016. http://hdl.handle.net/20.500.11794/27551.

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Les neurones dopaminergiques du mésencéphale (mDA) sont impliqués dans une variété de fonctions clefs du système nerveux central, incluant le mouvement volontaire, les processus affectifs, la récompense, l’attention, la mémoire de travail et l’apprentissage. La spécification des neurones mDA, de même que l’établissement des circuits dopaminergiques, sont finement régulés au cours du développement et requièrent l’activation spatiotemporelle complexe de facteurs de transcription et de leurs gènes cibles. La dégénérescence ou une perturbation de l’activité des neurones mDA peut mener au développement de troubles neurodégénératifs ou neuropsychiatriques graves, tels la maladie de Parkinson (PD), la schizophrénie (SCZ) et les troubles du spectre obsessif compulsif (OCD). Les facteurs de transcriptions Lmx1a et Lmx1b sont des déterminants précoces de la destinée dopaminergique, essentiels à la différenciation et à la spécification des neurones mDA. Des polymorphismes de LMX1A/B ont précédemment été associés à la SCZ et aux troubles du spectre OCD. Parmi les gènes développementaux sous le contrôle transcriptionnel de Lmx1a/b, nous avons identifié deux membres de la famille Slit et Trk (Slitrk), Slitrk2 et Slitrk5, comme contrôlant la formation des synapses excitatrices et inhibitrices afférentes aux neurones mDA. Des mutations de SLITRK2 et SLITRK5 furent également associées au développement de divers désordres neuropsychiatriques. Nous présentons ici le rôle de Lmx1a/b dans la régulation de l’activité électrophysiologique des neurones mDA, par leur régulation transcriptionnelle de Slitrk2 et Slitrk5. En utilisant un modèle de culture primaire de neurones mDA, nous avons identifié un rôle de Slitrk2 et de Slitrk5 dans la régulation postsynaptique de la synaptogénèse excitatrice et inhibitrice, respectivement. La perturbation de l’activité électrique des neurones mDA résultant de la perte ou du gain de fonction de Slitrk2/5 pourrait possiblement résulter en une perturbation de la libération de la dopamine aux noyaux cibles des neurones mDA, menant ainsi au développement de comportements pathologiques associés aux troubles neuropsychiatriques humains.
Mesodiencephalic dopaminergic (mDA) neurons regulate key functions of the mammalian central nervous system, including voluntary movement, affection, reward, attention, working memory and learning. The specification of mDA neurons and dopaminergic circuitry’s establishment are finely regulated during development and require specific and complex spatial and temporal activation of transcription factors and target genes. The degeneration of mDA pathways or their dysfunction can lead to severe neurodegenerative or neuropsychiatric disorders, including Parkinson’s disease (PD), schizophrenia (SCZ) and obsessive-compulsive disorder (OCD). Lmx1a and Lmx1b transcription factors are early determinants of the dopaminergic fate, essential to mDA neurons differentiation and specification. Polymorphisms of LMX1A/B were previously linked to SCZ and OCD. Within the transcriptional targets of Lmx1a/b, we identified to members of the Slit and Trk (Slitrk) family, Slitrk2 and Slitrk5, controlling excitatory and inhibitory afferent synapses formation of mDA neurons. Mutations of SLITRK2 and SLITRK5 were also previously linked to various neuropsychiatric diseases. We here present the role of Lmx1a/b in the regulation of the electrophysiological activity of mDA neurons, by their transcriptional regulation of Slitrk2 and Slitrk5. Using a mDA neurons’ primary cell culture paradigm, we identified a role of Slitrk2 and Slitrk5 in the post-synaptic regulation of excitatory and inhibitory synaptogenesis, respectively. The perturbation of mDA neurons’ electrophysiological activity, resulting from Slitrk2/5 loss or gain of function could lead to an alteration in dopamine release to mDA neurons target nuclei, and thus to the development of pathological behaviours associated with human neuropsychiatric diseases.
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Hakanen, Eva. "Återbrukets estetik - Uppländska trasryor : Förekomst, tillverkning, funktion och värde." Thesis, Uppsala universitet, Textilvetenskap, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-439775.

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Since the beginning of the early 20th century bed rugs have been interesting research objects, but only in passing researchers have paid attention to rugs woven with rags. Noone has taken a closer look upon the reasons why people have woven these rugs. What does the materials of the rag – like recycled garments and interior textiles in the form of clothing rags – have to tell about the times when these rugs were woven? Did the rag rugs have any specific function or were the materials available and therefore used? The main sources of information are 21 rag rugs from Roslagen in Uppland, with a varied amount of rags. They were woven during the latter half of 19th century, and estate inventories from Väddö- and Häverö Ship District have altogether given some answers to the primary question of this paper: in wich way can the examined bed rugs bear witness to the use and value of recycled textile materials and the view of these in the context of the community where they were manufactured and used? This research doesn´t give an answer to whether these rugs have any particular function or not. Instead these rag rugs can be looked upon as representing a general development of the society towards an increasing amount of textiles surplus material. This being due an increasing consumption of factory-made clothing and textiles, manufactured in factories, as well as the paper mills development from producing paper made of cellulose rather than textile waste. To this we can add a principle lingering on from the 19th century, of domestic production and a thrift of resources. This resulted in an obvious recycling of discarded textiles. The home weaving of interior textiles was still strong by the end of the 19th century, and in Rosagen there was also a long tradition of weaving and of using rugs in the beds. At the same time there was, in the coastal regions of Roslagen, a local need for warming covers in boats and boat houses. This demand was related to the shooting of seals and other hunting in the coastal areas, as well as in the fishing- and maritime trades.
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Beaubien, Francois. "Role of Slitrk family members in neurodevelopment." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=110496.

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The development of the nervous system is an extremely complex process where gene expression is tightly regulated, both spatially and temporally. Any gene disruption during neurodevelopment, from the complete non-transcription of the gene to a single nucleotide mutation, has the potential to lead to severe consequences in the organism. This situation is particularly well illustrated by the whole spectrum of neurological disorders affecting humans. Thanks to basic research at the gene and protein levels, some genetic causes for certain mental illness have been identified. This thesis focuses on a novel family of proteins termed the Slitrks. Initial characterization of the Slitrk family genes revealed that their expression is enriched in the central nervous system. Herein, I have performed a detailed analysis of the patterns of expression of the six members of the family in the mouse nervous system. I demonstrate that, despite some overlapping expression, several key brain regions express different combinations of Slitrks suggesting that the different family members may have distinct functions during nervous system development. I further demonstrate that members of the Slitrk family can regulate synapse formation in hippocampal neurons. More precisely, Slitrk1 is required for the formation of both excitatory and inhibitory synapses. Taken together, the results presented in my thesis indicate that Slitrks play an important role in the developing nervous system.
Le développement du système nerveux est un processus extrêmement complexe pendant lequel l'expression des gènes est contrôlée de façon précise temporellement et localement. Durant le neurodéveloppement, chaque dérégulation génétique, de l'arrêt complet de la transcription d'un gène jusqu'à la mutation d'un seul nucléotide, a le potentiel de mener à de graves conséquences pour l'organisme. Cette situation est particulièrement bien illustrée par l'ensemble des troubles neurologiques qui affectent l'humain.Cette thèse se concentre sur une nouvelle famille de protéines nommées Slitrks. La description préliminaire de cette famille a révélé que leur expression est enrichie dans le système nerveux central. Par conséquent, j'ai réalisé une analyse détaillée du patron d'expression des six membres de la famille dans le système nerveux de la souris. J'ai ainsi pu démontrer que malgré certains chevauchements d'expression, plusieurs régions du cerveau expriment différentes combinaisons de Slitrks. Cela laisse présager que certains membres de la famille Slitrks peuvent avoir des fonctions distinctes durant la formation du système nerveux. Au cours de mes travaux, j'ai aussi pu démontrer que les Slitrks peuvent réguler la formation des synapses dans les neurones de l'hippocampe. Plus précisément, Slitrk1 est requis à la fois pour la formation des synapses excitatrices et inhibitrices. Dans l'ensemble, les résultats présentés dans cette thèse indiquent que les Slitrks jouent un rôle important dans le développement du système nerveux.
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Valladares, Olcese Rodrigo. "Impiego di materiali cellulari per il miglioramento delle prestazioni della slitta portamandrino di una macchina fresatrice." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2012. http://amslaurea.unibo.it/4759/.

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Björn, Petronella. "De starkaste armar blev slitna från plogen : Krig, pest och missväxt i Gårdby socken 1695-1721 ur ett båtsmansperspektiv." Thesis, University of Kalmar, School of Human Sciences, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:hik:diva-1020.

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Det huvudsakliga syftet med min uppsats var att studera hur tre olika aspekter påverkade Gårdby socken och dess båtsmän under Stora nordiska kriget, nämligen krig, pest och missväxt. Med hjälp av de källor jag har studerat, militära rullor, kyrkoböcker och mantalslängder, har jag fått fram hur livet kunde te sig för de indelta båtsmännen men också hur pestens verkningar påverkade socknen mer långsiktigt än vad krigets utskrivningar gjorde. Jag har även studerat hur missväxten föll ut i Gårdby och jämfört detta med till exempel byn Andersvattnet, Stockholm och övriga riket.

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Lekeš, Jonáš. "Výroba dentálních náhrad." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2013. http://www.nusl.cz/ntk/nusl-230811.

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Tato práce popisuje části dentálních náhrad, lékařské pojmy, které se s nimi vážou a vysvětluje proces a problematiku koncepce a výroby těchto částí. Různé druhy biomateriálů jako kovy, keramika, polymery či kompozity jsou zde popsány, hlavní důraz je však kladen na titanové a chrom kobaltové slitiny a korozivzdorné oceli. Experimentální část nabízí 2 řešení zlepšení výroby součásti. První část experimentální části se zabývá zlepšením kvality styčné plochy pilíře zvýšením hustoty síťování součásti. Druhá část nabízí nahrazení operace frézování operací vrtání. Byly vybrány nástoje od 4 výrobců. Pro nalezení vhodného nástroje jsou provedeny 2 testy vrtání a vybrán nástroj vhodný pro obrábění titanové a chrom kobaltové slitiny.
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Rosander, Henrik, and Selma Pasic. ""Människor är det enda djur som kan slita ut din själ och pissa på den" - En studie i hur gymnasieelever ser på ondska." Thesis, Kristianstad University College, School of Teacher Education, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:hkr:diva-4906.

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Syftet med den här uppsatsen var att jämföra hur gymnasieelever kan tänka kring ondska i förhållande till några välkända filosofernas sätt att tänka kring ondska. För att kunna ta reda på detta så gjorde vi en undersökningen på två gymnasieskolor, i två olika klasser i årskurs 3. Metoden som används var en kvalitativ undersökningsmetod, där eleverna fick skriva små uppsatser utifrån ett frågeformulär med öppna frågor. Resultaten nåddes genom analyser av dessa uppsatser, och som analysverktyg användes olika filosofiska tänkares syn på ondska. Resultaten visade att flertalet av eleverna inte hade varit med om något som de skulle vilja kalla för ondska. Många skulle hellre vilja kalla det för elakhet. Resultaten visade också att några utav dem som hade upplevt ondska beskrev detta som mobbning. Resultaten visar även att samtliga elever inte såg ondska som något transcendent, utan som något högst mänskligt, något som fanns inom människan.

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Klepárníková, Eliška. "Interakce poloroztavené slitiny s pevným materiálem při vzájemném pohybu." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2019. http://www.nusl.cz/ntk/nusl-442481.

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This thesis is deals with the suitability of Ag-Sn-Sb alloy for extrusion and selection of suitable materiál for the extruder nozzle. The theoretical part of this thesis deals with the general possibilities of 3D metal printing, especially the metal printing in the semi-solid phase and with it‘s problems. The experimental part describes the development of semi-solid alloys testing device and the research od the alloy and its interactions with solid materials in mutual motion. Analyzis of mechanical and chemical influence between alloy and solid material were performed by visual investigation and analysis of elements by EDS detector. The results of these analyzes led to the choise of nozzle material suitable for extrusion of Ag-Sn-Sb alloy.
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Cieslar, Jiří. "Studium faktorů ovlivňujících odolnost proti opotřebení kovových materiálů." Doctoral thesis, Česká zemědělská univerzita v Praze, 2016. http://www.nusl.cz/ntk/nusl-259632.

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This thesis investigates the suitable chemical composition of a iron alloy with improved wear resistance. A unique set of alloys with a specifically designated chemical composition was manufactured for experiments. Their properties in defined abrasive conditions was studied in laboratory conditions. Wear resistance was determined on an experimental bench with bound particles. Material properties description was always complemented with information gained during material metallographic structure investigations. All the results were compared with results achieved for commercially available weld deposition materials (specifically designated for abrasion conditions). These (weld deposition) materials were subjected to an identical set of laboratory experiments and additionally to a set of experiments under inservice conditions. This thesis offers new knowledge about the relationship between material hardness, material structure and wear resistance. The outlined results also give evidence about the correlation between results gained under laboratory conditions and those gained under in-service conditions (in relation to material structure and hardness). At the end of the thesis the knowledge gained from these experiments is applied to a specific application the service life extension of plough blade segments. On this basis a new material is designed which will extend service life without additional demands on the costs, and the approach to the renovation of worn plough blade segments is justified.
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Gamanov, Štěpán. "Příprava slitiny s vysokou entropií cestou mechanického legování." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2019. http://www.nusl.cz/ntk/nusl-400831.

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This thesis deals with topic of high entropy alloys. The teoretical part explains what are high entropy alloys, how are they different from conventional alloys, how is their chemical composition proposed and what potencial these alloys have. The experimental part describes procedures of preparation of three high entropy alloys witch consists of Co, Cr, Fe, Ni and Ti, where the concentration of all elements except Ti remains the same. These alloys were prepared via mechanical alloying and sintered by SPS process. Crucial part of this thesis is characterization of these three alloys with EDS and XRD supported by hardness measuring and tensile tests.
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Books on the topic "Slitrya"

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I, Manokhin A., ed. Teorii͡a︡ neravnovesnoĭ kristallizat͡s︡ii ploskogo slitka. Moskva: "Nauka", 1992.

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2

Borisov, V. T. Teorii͡a︡ dvukhfaznoĭ zony metallicheskogo slitka. Moskva: "Metallurgii͡a︡", 1987.

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3

Mirsalimov, V. M. Napri͡a︡zhennoe sostoi͡a︡nie i kachestvo nepreryvnogo slitka. Moskva: "Metallurgii͡a︡", 1990.

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4

Samoĭlovich, I͡U A. Mikrokompʹi͡uter v reshenii zadach kristallizat͡sii slitka. Moskva: "Metallurgii͡a", 1988.

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5

Socialstyrelsen, Sweden. Från slitna honnörsord till praktisk verksamhet: Slutrapport från Socialstyrelsens primärvårdsuppföljning. Stockholm]: Socialstyrelsen, 1998.

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6

institut, Maĭkopskiĭ gosudarstvennyĭ tekhnologicheskiĭ. Slitye pochvy: Genezis, svoĭstva, sot͡s︡ialʹnoe znachenie : materialy konferent͡s︡ii, 6-13 senti͡a︡bri͡a︡ 1998 goda, MGTI, Maĭkop. Maĭkop: Adygei͡a︡, 1998.

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7

Krasavkin, V. K. Zdesʹ grad Petra i flot naveki slity: Istorii︠a︡ morskikh chasteĭ v gorode na Neve, 1703-2003. Sankt-Peterburg: Russko-Baltiĭskiĭ informat︠s︡ionnyĭ t︠s︡entr "BLITS", 2004.

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8

The Slithy Toves. Aster Mountain Press, 2013.

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9

Slitye pochvy Moldavii: Genezis, svoĭstva, ėvoli͡u︡t͡s︡ii͡a︡, ispolʹzovanie. Kishinev: "Shtiint͡s︡a", 1990.

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Pecori, Fabrizio. Groenlandia in slitta, per mare, per aria. Cartman Edizioni, 2005.

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Book chapters on the topic "Slitrya"

1

"Game 48 Slithy Toves and Mome Raths - Case study: ‘make or buy?’." In Financial Games for Training, 173–75. Routledge, 2018. http://dx.doi.org/10.4324/9781351158244-58.

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Conference papers on the topic "Slitrya"

1

Morrison, Kendall. "Abstract 4332: Development of AGS15E, a novel antibody drug conjugate targeting SLITRK6 for the treatment of bladder cancer." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-4332.

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Liu*, Lele, Changling Liu, Chengfeng Li, Jianye Sun, Qingguo Meng, and Hongyuan Zhang. "Determining the permeability of hydrate-bearing slity-fine sands with water transient flow." In International Geophysical Conference, Qingdao, China, 17-20 April 2017. Society of Exploration Geophysicists and Chinese Petroleum Society, 2017. http://dx.doi.org/10.1190/igc2017-341.

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YANG, Peng, Jeffrey Coleman, Ying Li, Yi Zhang, Candice Junge, Kendall Morrison, Fernando Donate, David Stover, and Karen Morrison. "Abstract 1274: SLITRK6, the target of a novel antibody drug conjugate AGS15E, is expressed in bladder and other cancers." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-1274.

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Shostak, Yuriy, Suzanne Said, Deanna L. Russell, Michael D. Mattie, Mi Sook Chang, Ashley Christensen, Karen Morrison, Kendall Morrison, David Stover, and Pia Challita-Eid. "Abstract 2047: Discovery and molecular characterization of AGS-15/SLITRK6 as a novel target for antibody-mediated therapeutic development in bladder cancer." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-2047.

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