Dissertations / Theses on the topic 'Sleep disordered breathing (SDB)'
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kuo, Tracy F. "Sleep-disordered breathing (SDB) and neuropsychological function: A community sample study." Diss., The University of Arizona, 2000. http://hdl.handle.net/10150/284215.
Full textDavies, Robert J. O. "Sleep disordered breathing and the cardiovascular system." Thesis, University of Southampton, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.404009.
Full textSmith, Lindsay Anne. "Sleep-disordered breathing and chronic heart failure." Thesis, University of Edinburgh, 2009. http://hdl.handle.net/1842/29371.
Full textPirilä-Parkkinen, K. (Kirsi). "Childhood sleep-disordered breathing – dentofacial and pharyngeal characteristics." Doctoral thesis, Oulun yliopisto, 2011. http://urn.fi/urn:isbn:9789514296024.
Full textTiivistelmä Väitöskirjatyön tarkoituksena oli selvittää lasten unenaikaisten hengityshäiriöiden yhteyttä kasvojen ja leukojen kasvuun, purennan kehitykseen sekä ylempien hengitysteiden rakenteeseen. Lisäksi tutkittiin, kuinka luotettavasti hammaslääkäreiden käytössä olevin menetelmin pystytään arvioimaan lasten ahtautuneita ilmateitä. Tutkimusaineistossa oli mukana 70 lasta (36 tyttöä, 30 poikaa, ikä 4.2–11.9 vuotta), joilla diagnosoitiin unenaikainen obstruktiivinen hengityshäiriö vuosina 2000–2002. Lapsille tehtiin kliiniset tutkimukset oikojahammaslääkärin ja korva-, nenä- ja kurkkutautien erikoislääkärin toimesta sekä otettiin lateraalikallokuva ja hampaistosta kipsimallijäljennökset. Lisäksi ylempien hengitysteiden magneettitutkimus suoritettiin 36 lapselle eri pään asennoissa. Verrokkiryhmässä oli sama ikä- ja sukupuolijakauma kuin tutkimusryhmässä. Tulokset osoittivat, että unenaikaisista hengityshäiriöistä kärsivillä lapsilla horisontaalinen ylipurenta oli suurentunut, vertikaalinen ylipurenta oli pienentynyt, ylähammaskaari oli kapeampi ja alahammaskaari lyhyempi kuin terveillä verrokeilla. Alaetualueen ahtaus ja etualueen avopurenta olivat yleisempiä niillä lapsilla, joilla oli vaikeampiasteinen hengityshäiriö. Lasten unenaikaiset hengityshäiriöt liittyivät suurentuneeseen leukojen väliseen kokoepäsuhtaan, alaleuan avautuvaan kasvumalliin, pidempään ja paksumpaan pehmeään suulakeen, kieliluun alempaan asentoon, kohonneeseen pään asentoon sekä ahtaampiin nielun ilmatilan mittoihin verrattaessa terveisiin lapsiin. Häiriön vaikeusaste korreloi suurempiin poikkeamiin nielun mitoissa. Lapsilla, joilla todettiin unenaikainen hengityshäiriö, magneettitutkimukset osoittivat nielun olevan ahdas. Pään asennon vaikutukset ilmatien rakenteeseen poikkesivat unenaikaisista hengityshäiriöistä kärsivillä lapsilla. Saadut tulokset osoittivat, että hengitystapa voi vaikuttaa hampaiston, kasvojen ja leukojen rakenteiden kehitykseen. Tietyt kasvojen ja leukojen piirteet puolestaan saattavat altistaa häiriön kehittymiselle. On tärkeää tunnistaa nämä merkit, jotta kehitystä voidaan ohjata suotuisampaan suuntaan. Tutkimukset osoittivat, että kefalometrinen analyysi on luotettava arvioitaessa nenänielun sekä pehmeän suulaen takana olevan ilmatilan kokoa. Nielurisojen kliinisen koon arviointi on luotettava arvioitaessa alemman suunielun ilmatilan kokoa
Aran, Reza. "Craniofacial morphology and sleep disordered breathing in children." Thesis, University of British Columbia, 2013. http://hdl.handle.net/2429/44379.
Full textKaminska, Marta. "Sleep-disordered breathing and fatigue in multiple sclerosis." Thesis, McGill University, 2011. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=103496.
Full textLa fatigue est fréquente et incapacitante dans la sclérose en plaque (SP). Elle est distincte de la somnolence. La fatigue et la somnolence ont été associées aux troubles respiratoires du sommeil, particulièrement à l'apnée obstructive du sommeil (AOS). La fatigue dans la SP est vraisemblablement multifactorielle, mais l'AOS pourrait y jouer un rôle important. Les principaux objectifs de ce projet étaient d'évaluer le rapport entre l'AOS et la fatigue ainsi que la somnolence chez les patients atteints de SP comparativement au sujets témoins, et d'évaluer les facteurs associés à la fatigue sévère chez les sujets atteints de SP. Des patients atteints de SP stables et ambulatoires sans troubles du sommeil connus ont été recrutés à la clinique de SP de l'Hôpital Neurologique de Montréal. Le groupe de sujets contrôle a été assorti en âge et sexe. Tous les participants ont passés une polysomnographie diagnostique et un test itératif de latence à l'endormissement (mesure objective de la somnolence diurne). La fatigue fut mesurée par la 'Fatigue Severity Scale' (FSS) et le 'Multidimensional Fatigue Inventory' (MFI), et la somnolence subjective avec l'échelle de somnolence Epworth (ESS). Les autres variables étaient l'âge, le sexe, l'indice de masse corporel, le niveau d'incapacité lié à la SP, la dépression, la douleur et la sévérité du syndrome des jambes sans repos. L'AOS, défini par un indice d'apnée-hypopnée (IAH) ≥ 15, a été retrouvée chez 36 des 62 (58%) sujets SP et 5 des 32 (47%) sujets témoins – rapport de cote (RC, IC 95%) 1.57 (0.67, 3.74). Après ajustement pour les facteurs confondants, la fatigue sévère (FSS > 5) et le MFI – fatigue mentale (> médiane du groupe) étaient associés avec l'IAH et les micro-éveils respiratoires, chez les sujets SP mais non chez les sujets contrôle. Le MFI – fatigue mentale, chez les sujets SP, était aussi associé à l'hypoxémie intermittente. Ni la somnolence subjective, ni objective n'étaient associées à l'AOS dans aucun des 2 groupes. Dans un modèle à plusieurs variables pour les sujets SP seulement, les seules variables prédisant la fatigue sévère étaient le niveau d'incapacité – RC (IC 95%) 1.88 (1.18, 3.33) et l'AOS sévère (IAH ≥ 30) – RC (IC 95%) 19.55 (2.31, 322.09). En résumé, quoique l'AOS n'aie pas été plus fréquente dans la SP que chez les sujets témoins, elle était associée à la fatigue sévère chez les sujets SP seulement. Aucune association avec la somnolence n'a été mise en évidence. La fatigue sévère chez les sujets SP était associée de façon marquée à l'AOS sévère, et de façon moins prononcée au niveau d'incapacité. Comme l'AOS est une condition qui se traite, ces résultats ouvrent la porte à des recherches plus poussées qui pourraient ultérieurement changer la prise en charge des patients atteints de SP avec fatigue sévère.
Johnston, Christopher David. "Sleep-disordered breathing : a cephalometric and clinical study." Thesis, Queen's University Belfast, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313925.
Full textBruyneel, Marie. "Ambulatory diagnostic and monitoring techniques for sleep disordered breathing." Doctoral thesis, Universite Libre de Bruxelles, 2015. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/216824.
Full textAmbulatory diagnostic and monitoring techniques for sleep disordered breathingSleep disordered breathing (SDB), including obstructive sleep apnea syndrome (OSAS), is directly related to obesity. Significant morbi-mortality is associated with OSAS, explaining the increasing demand for in-hospital polysomnography (PSG), the reference diagnostic method. As this technique is complex and time-consuming, many simplified portable monitoring (PM) devices for home sleep testing have been developed. However, the ability of PM devices to detect OSA remains limited: sleep time is not correctly assessed, OSA severity is underestimated, false negative results occur and the failure rate of the tests is high, up to 30%. Home-PSG (H-PSG) is an interesting alternative, avoiding many of these drawbacks. In the first part of this work, we studied the tool in an original study comparing H-PSG and in-lab PSG. Diagnostic efficacy was good and the failure rate low (4.7 vs 1.5%). Patients slept in their own environment and thus sleep quality was better. We were then interested by reviewing recent literature data regarding prospective randomised trials comparing H-PSG and in-lab PSG. We concluded that H-PSG is an excellent alternative for in-lab PSG, allowing not only OSA detection but also diagnosis of a large panel of other sleep disorders (periodic leg movements during sleep, circadian disorders,). As the best place to perform set-up for H-PSG remained unknown, we studied, in another prospective randomised study, the recording’s quality obtained in both settings. As no difference was observed, lab set up was found to be the simpler option for performing H-PSG. We then tested, in a prospective pilot study, real-time telemonitoring (TM) of H-PSG in order to enhance recording quality. Results were encouraging but we faced some technical problems. In a second study, we applied TM coupled with PSG to detect SDB in acute coronary syndrome, in patients too unstable to come in the sleep lab. We compared also PSG results to polygraphy (PG). Surprisingly, 82% of patients suffered from SDB. PSG was much more sensitive than PG to screen SDB in this population and TM improves recording quality. In the second part of this work, we have used actigraphy (Act) to assess sleep and physical activity in OSA patients in real-life conditions. Firstly, in a retrospective study, we documented these parameters before treatment. In a second multicentre study, we evaluated the changes in sleep schemes and physical activity under continuous positive airway pressure (CPAP) in 150 OSA patients. We observed that sleep time was increased under CPAP, but physical activity was not improved, contrarily to sleepiness and quality of life. In conclusion, we have shown through these works the clinical interest of two excellent ambulatory tools, H-PSG and Act, for OSA management. Potential clinical implications include enhanced healthcare accessibility, earlier treatment initiation and a closer follow-up of treated patients, through ambulatory tools, in a comfortable environment for the patients.
Doctorat en Sciences médicales (Médecine)
info:eu-repo/semantics/nonPublished
Wang, David. "Sleep disordered breathing in stable methadone maintenance treatment patients /." Connect to thesis, 2006. http://eprints.unimelb.edu.au/archive/00002992.
Full textSutton, Amy M. "Executive Function in the Presence of Sleep Disordered Breathing." Digital Archive @ GSU, 2008. http://digitalarchive.gsu.edu/cps_diss/16.
Full textRoss, Kristie R. "Sleep Disordered Breathing, Obesity, and Asthma Severity in Children." Case Western Reserve University School of Graduate Studies / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=case1291296902.
Full textNahapetian, Ryan, Graciela E. Silva, Kimberly D. Vana, Sairam Parthasarathy, and Stuart F. Quan. "Weighted STOP-Bang and screening for sleep-disordered breathing." SPRINGER, 2015. http://hdl.handle.net/10150/623579.
Full textWard, Neil Robert. "Diagnosis of sleep-disordered breathing in chronic heart failure." Thesis, Imperial College London, 2011. http://hdl.handle.net/10044/1/9597.
Full textTheorell-Haglöw, Jenny. "Sleep and Sleep-disordered Breathing in Women : Associations with Daytime Symptoms and Metabolism." Doctoral thesis, Uppsala universitet, Lungmedicin och allergologi, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-99080.
Full textNau, Jeffrey A. "Association Between Age-Related Macular Degeneration and Sleep-Disordered Breathing." ScholarWorks, 2017. https://scholarworks.waldenu.edu/dissertations/3463.
Full textVazir, Ali. "Prevalence and characteristics of sleep disordered breathing in mild heart failure." Thesis, Imperial College London, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.437371.
Full textBrady, Emer Margaret. "Investigating the relationship between sleep disordered breathing, glycaemic control and inflammation." Thesis, University of Leicester, 2009. http://hdl.handle.net/2381/9926.
Full textAtalla, Angela. "Sleep disordered breathing in chronic heart failure : causes, consequences and treatment." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/11672.
Full textKimura, Kaku. "Sleep-disordered breathing at an early stage of amyotrophic lateral sclerosis." Kyoto University, 1999. http://hdl.handle.net/2433/181697.
Full textLazareck, Lisa. "Investigation of breathing-disordered sleep quantification using the oxygen saturation signal." Thesis, University of Oxford, 2008. https://ora.ox.ac.uk/objects/uuid:63671d89-e3a4-49e6-a486-3f605cacd1c1.
Full textHarbison, Joseph Augustine. "The course, associations and clinical significance of sleep disordered breathing following stroke." Thesis, University of Newcastle upon Tyne, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.270779.
Full textMahadevan, Anandi. "Ischemic Feature Identification and Its Relation to Sleep Disordered Breathing in Sleep Heart Health Study Subjects." University of Akron / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=akron1384984982.
Full textCohen, Jeffrey M. "Sleep Disordered Breathing and Sleep Duration and the Risk of Psoriasis and Melanoma in the United States." Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:15821589.
Full textTakegami, Misa. "Simple four-variable screening tool for identification of patients with sleep-disordered breathing." 京都大学 (Kyoto University), 2009. http://hdl.handle.net/2433/126592.
Full text0048
新制・課程博士
博士(社会健康医学)
甲第15000号
社医博第27号
新制||社医||6(附属図書館)
27450
UT51-2009-R724
京都大学大学院医学研究科社会健康医学系専攻
(主査)教授 今中 雄一, 教授 川上 浩司, 教授 三嶋 理晃
学位規則第4条第1項該当
Felix, Moscoso Monica, Galvan Jack Denegri, Loayza Fernando Ortega, and Adrian V. Hernandez. "Respiratory Therapy in Chronic Heart Failure Patients Complicated With Sleep-Disordered Breathing: Potential Study Bias." Journal of the Japanese Circulation Society, 2016. http://hdl.handle.net/10757/611825.
Full textMacLeod, Kendra Deanne. "Evaluating Adherence to Continuous Positive Airway Pressure Therapy in Children with Sleep-Disordered Breathing." University of Cincinnati / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1235768185.
Full textMulvaney, Shelagh. "Behavioral and cognitive correlates of sleep-disordered breathing in a community sample of school children." Diss., The University of Arizona, 2002. http://hdl.handle.net/10150/280100.
Full textSUKEGAWA, MAYO, AKIKO NODA, TARO SOGA, YUKI ADACHI, YOSHINARI TSURUTA, NORIO OZAKI, YASUO KOIKE, and 真代 助川. "COMPARISON OF SLEEP-DISORDERED BREATHING AND HEART RATE VARIABILITY BETWEEN HEMODIALYSIS AND NON-HEMODIALYSIS DAYS IN HEMODIALYSIS PATIENTS." Nagoya University School of Medicine, 2008. http://hdl.handle.net/2237/10544.
Full textGoodwin, III James Lester. "The natural history of sleep disordered breathing in 6-11 year old Caucasian and Hispanic children." Diss., The University of Arizona, 2002. http://hdl.handle.net/10150/280181.
Full textBadgley, Jennifer Ayala Chute Douglas L. "Sleep-disordered breathing in children and adolescents with Systemic Lupus Erythematosus and its association with executive functioning /." Philadelphia, Pa. : Drexel University, 2008. http://hdl.handle.net/1860/2802.
Full textMietchen, Jonathan James. "Parent-Reported Deficits in Executive Function and Sleep-Disordered Breathing in Adolescent Behavioral Weight Loss Program Participants." BYU ScholarsArchive, 2016. https://scholarsarchive.byu.edu/etd/6386.
Full textMuscat, Vanessa. "Improving the diagnosis of obstructive sleep disordered breathing in infants by incorporating esophageal manometry into conventional polysomnography." Title page and summary only, 1999. http://web4.library.adelaide.edu.au/theses/09SB/09sbm985.pdf.
Full textSpine title: Diagnosing obstructive sleep disordered breathing in infants. Includes bibliographical references (leaves 32-35).
Minami, Takuma. "Impact of sleep-disordered breathing on glucose metabolism among individuals with a family history of diabetes: the Nagahama study." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/263558.
Full textHarada, Yuka. "Differences in Associations between Visceral Fat Accumulation and Obstructive Sleep Apnea by Sex." Kyoto University, 2014. http://hdl.handle.net/2433/189343.
Full textHernandez, A. V., Adrian V. Hernandez, Anne Jeon, Jack Denegri-Galvan, Fernando Ortega-Loayza, Monica Felix-Moscoso, Vinay Pasupuleti, and Roop Kaw. "Use of adaptive servo ventilation therapy as treatment of sleep-disordered breathing and heart failure: a systematic review and meta-analysis." Springer, 2020. http://hdl.handle.net/10757/651733.
Full textRevisión por pares
Spörndly-Nees, Søren. "Physical activity and eating behaviour in sleep disorders." Doctoral thesis, Uppsala universitet, Sjukgymnastik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-308395.
Full textTideström, Löfstrand Britta. "Sleep Disordered Breathing and Orofacial Morphology in Relation to Adenotonsillar Surgery : Development from 4-12 Years in a Community Based Cohort." Doctoral thesis, Uppsala universitet, Institutionen för kirurgiska vetenskaper, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-108031.
Full textTideström, Löfstrand Britta. "Sleep disordered breathing and orofacial morphology in relation to adenotonsillar surgery development from 4-12 Years in a community based cohort /." Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-108031.
Full textKrenn, Marion [Verfasser], Michael [Akademischer Betreuer] Arzt, and Thomas [Akademischer Betreuer] Kühnel. "Prognostic impact of sleep disordered breathing and its treatment in heart failure: an observational study / Marion Krenn. Betreuer: Michael Arzt ; Thomas Kühnel." Regensburg : Universitätsbibliothek Regensburg, 2011. http://d-nb.info/1048725677/34.
Full textJohansson, Peter. "Health‐related quality of life, depression, sleep and breathing disorders in the elderly : With focus on those with impaired systolic function/heart failure." Doctoral thesis, Linköpings universitet, Kardiologi, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-15784.
Full textHill, Elizabeth Anne. "Prevalence and treatment of obstructive sleep apnoea/hypopnoea syndrome in adults with Down syndrome." Thesis, University of Edinburgh, 2016. http://hdl.handle.net/1842/22917.
Full textJohn, Angela Beatriz. "Determinação de padrões ventilatórios e avaliação de estratégias de rastreamento de transtornos respiratórios durante o sono em pacientes candidatos à cirurgia bariátrica." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2015. http://hdl.handle.net/10183/139775.
Full textIntroduction: Obesity is a growing public health problem and the main risk factor for sleep-disordered breathing (SDB), including obstructive sleep apnea (OSA) and nocturnal hypoventilation. Bariatric surgery has become an option for the treatment of significant obesity. Early detection of SDB preoperatively is essential, since these disorders are associated with an increased risk of perioperative complications. Several screening tools for SDB, with a more simplified approach than polysomnography (PSG), have been proposed in recent years, but not all of them have been evaluated in a population of obese patients. Objective: To determine ventilatory patterns in obese candidates for bariatric surgery and evaluate three SDB screening strategies in this population. Methods: Eligible participants were all patients aged ≥18 years with grade III (body mass index [BMI] ≥ 40kg/m2) or grade II (BMI ≥35 kg/m2) obesity and obesity-related comorbidities who were referred for evaluation for bariatric surgery. Exclusion criteria were heart disease and/or severe or decompensated pulmonary disease. Ninety-one patients were evaluated by three strategies: (1) Clinical (Epworth Sleepiness Scale and STOP-Bang questionnaire, Berlin questionnaire and Sleep Apnea Clinical Score [SACS] plus blood gas analysis [BGA]); (2) Oximetry (overnight Holter-oximeter monitoring and BGA); and (3) Portable (overnight portable monitoring and capnography). All tests were compared with the gold standard, PSG, for the diagnosis of OSA. Results: The sample consisted of 77 women (84.6%) with a mean (SD) age of 44.7 (11.5) years and BMI of 50.1 (8.2) kg/m2. The ventilatory patterns identified were snoring, isolated nocturnal hypoxemia, OSA, and nocturnal hypoventilation associated with OSA. Polysomnographic data showed OSA in 67 of 87 patients (77%), 26 with mild, 19 with moderate and 22 with severe disorder. Twenty patients (23%) had a diagnosis of snoring, and two of them also had isolated nocturnal hypoxemia without concomitant OSA or hypoventilation. Nocturnal hypoventilation associated with OSA was detected by capnography in one patient. In the Clinical Strategy, the best result was obtained with the STOP-Bang score ≥6 in patients with an apnea-hypopnea index (AHI) ≥30 (overall accuracy of 82.8%). In the Oximetry Strategy, the cutoff values with the highest sensitivity and specificity for AHI ≥5, ≥10, ≥15, and ≥30 were total recording time with peripheral oxygen saturation (SpO2)< 90% for at least 5 minutes, 3% oxygen desaturation index (ODI) ≥22 desaturations/hour of recording, and 4%ODI ≥10 and ≥15 desaturations/hour of recording. All areas under the curve (AUC) were above 0.850. For AHI ≥5, 4%ODI ≥10 had a sensitivity of 97%, specificity of 73.7%, positive predictive value of 92.8%, negative predictive value of 87.5%, and overall accuracy of 91.8%. In the Portable Strategy, the respiratory disturbance index (RDI) was a good predictor of OSA in various cutoff values of AHI (AUC of 0.952 to 0.995). The highest sensitivity and specificity were obtained at similar cutoff values for RDI and AHI, especially for AHI ≥10 and ≥30. The maximum overall accuracy was 93.9% for RDI ≥5, ≥10, and ≥30 in their corresponding AHI. Based on these results, combined strategies were tested consisting of the STOP-Bang score ≥6 combined with 4%ODI ≥10 or ≥15. The best balance between sensibility and specificity and the maximum accuracy were achieved with the strategy composed by STOP-Bang ≥6 and 4%ODI ≥15 in patients with severe OSA. Conclusions: The frequency of occurrence of SDB in obese individuals undergoing evaluation for bariatric surgery was high, and OSA was the most frequent occurrence. Currently available questionnaires were insufficient to screen for OSA in this population, with the exception for the STOP-Bang score ≥6 in patients with severe OSA. The use of an objective physiological measure, such as Holter-oximetry monitoring, was useful as a screening tool for OSA in obese patients. Portable monitoring showed increased accuracy, especially in extreme AHI values, with results comparable to those obtained with PSG. The PSG could be reserved only for certain cases where diagnostic confirmation is necessary.
Koike, Yasuo, Seiichi Nakata, 聖子 宮田, Seiko Miyata, Akiko Noda, Hidehito Yagi, Eriko Yanagi, et al. "Daytime polysomnography and portable recording device for diagnosis and CPAP therapy in patients with obstructive sleep apnea syndrome." Thesis, Springer Berlin, 2007. http://hdl.handle.net/2237/11067.
Full text"Daytime polysomnography and portable recording device for diagnosis and CPAP therapy in patients with obstructive sleep apnea syndrome" Sleep and Breathing, v.11, n.2 (2007) pp.109-115 を、博士論文として提出したもの。
Zhu, Kaixian. "Évaluation sur banc d'essai des algorithmes des machines ventilatoires." Thesis, Université Paris-Saclay (ComUE), 2016. http://www.theses.fr/2016SACLS021/document.
Full textSleep disordered breathing including sleep apnea is a major public health problem. It contributes to daytime sleepiness and is associated with chronic diseases. In recent years, a variety of ventilation devices have been developed with the objective of treating sleep disorders related to the upper airway obstruction (obstructive apnea) or the central command (central apnea). These devices operate with different algorithms, which are little known and protected by the device manufacturers. Since most devices are evaluated during patient treatment, it is difficult to compare them in the same conditions due to inter- and intra-patient variability. Bench test has been proposed to evaluate the device responses in standardized and reproducible conditions. This thesis was aimed to develop a respiratory bench model able to reproduce patients’ signals and also in concordance with human physiology. The bench model can take into account the pressure responses of tested devices and works in a “closed loop” setting.With this bench model, several commercially available auto-titrating continuous positive airway pressure devices were evaluated for their auto-titration algorithms as well as their pressure-relief modes. Also, three adaptive servo-ventilation devices were evaluated by subjecting various sleep disordered breathing events that were generated by another bench model of a similar principle. We demonstrated that eleven auto-titrating continuous positive airway pressure devices were not equivalent in terms of their treatment efficacy and the data accuracy in the device report. The pressure-relief modes may attenuate the efficacy if not adjusted at the time of their introduction. The responses of adaptive servo-ventilation devices were not sufficient to normalize the breathing flow and their efficacy depended on the initial settings.The current certification process of these ventilatory devices, which focus mainly on clinical aspects, may be completed by the results of our bench
Chaccur, Danilo Chucralla. "Avaliação da alteração da dimensão vertical na qualidade do sono em pacientes idosos portadores de prótese totais bimaxilares." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/23/23150/tde-18112010-110424/.
Full textThere is a high prevalence of edentulism and problems associated to it in the elderly population. A decrease in occlusal vertical dimension (OVD) is one of such problems which hinder the stomatognathic system. Therefore, it is important to investigate disorders associated with the weakening of musculature, such as the obstructive sleep apnea syndrome (OSAS), in such patients. Therapeutic measures of low cost and high efficacy, such as intraoral devices (ID), are needed in order to remove the obstruction of airway flow and improve the patients sleep quality. The present study aimed to assess the subjective and objective effectiveness of an ID, specially designed to increase OVD avoiding mandibular protrusion, in 19 elderly patients who wore upper and lower full dentures (FD), before and after therapy. For this purpose, sleep quality was analyzed using questionnaires and polysomnography at three distinct moments: baseline without FDs, with FDs, and with ID. It was possible to conclude that the ID tested can contribute to the improvement of the quality of sleep in patients as well as in their partners, as it significantly decreased snoring; the participants referred that they preferred to use the ID to sleep. However, the use of ID in this sample of people did not significantly improve the parameters assessed in polysomnography, when compared to the baseline (without FDs) and, therefore, should not be used as treatment for OSAS. Thus, further studies are needed in order to better evaluate dimensions of the upper airways as well as side effects for OSAS therapy in patients who wear upper and lower FDs.
Cao, Xu [Verfasser], Georg [Akademischer Betreuer] Schmidt, Christof [Gutachter] Kolb, and Georg [Gutachter] Schmidt. "Risk prediction after myocardial infarction by cyclic variation of heart rate, a surrogate of sleep-disordered breathing assessed from Holter ECGs / Xu Cao ; Gutachter: Christof Kolb, Georg Schmidt ; Betreuer: Georg Schmidt." München : Universitätsbibliothek der TU München, 2020. http://d-nb.info/1241246777/34.
Full textFiorott, Bruna Santos. "Alterações faciais anatômicas e funcionais em escolares do município de Vitória, ES." Universidade Federal do Espírito Santo, 2012. http://repositorio.ufes.br/handle/10/5871.
Full textIntroduction: Mouth breathing pattern in children may have negative physical, psychological and social effects according to the intensity and duration. The relationship between mouth breathing and sleep-disordered breathing (SDB) is derived from clinical conditions ranging in increasing severity from primary snoring, to upper airway resistance syndrome and obstructive sleep apnea syndrome. The main cause of mouth breathing and SDB is associated to narrowing of the upper airway in varying degrees. This association is of concern due to its immediate or late clinical implications like disturbances in craniofacial growth, behavioral changes, impaired learning and cognitive functions, negatively influencing quality of life. Objective: Assess the prevalence of mouth breathers (MB) and the presence of facial anatomical changes that affect children with SDB, in addition to assessing self-perceived quality of life of MB. Methodology: A cross-sectional observational sample of 687 students from public schools, aged 6-12 years old, evaluated by medical history, clinical examination and lip seal tests. Self-perceived quality of life of MB was obtained through questionnaire (Ribeiro, 2006). Results: In the total sample, 520 (75,7%) students were nasal breathers and 167 (24,3%) were MB. Among MB, 40,1% had obstructive hypertrophy of the palatine tonsils, 26,4% had Mallampati score III and IV, 35,3% has excessive overjet, 23,4% had anterior open bite, 15,6% had posterior crossbite, 53.9% had atresic palate, 35.9% had interlabial gap, 31% reported problems related to sleep and 9,0% reported having the feeling of stop breathing while asleep. Conclusion: The prevalence of facial anatomical and functional changes in mouth breathers students was high, however the self-perception of quality of life was considered good. It is recommended the adoption of public health policies aimed at diagnosis, counseling and treatment of students at this age group, in which the relief of signs and symptoms can promote normal craniofacial growth and reduce future risk of SDB
Introdução: O padrão de respiração bucal em crianças pode gerar repercussões negativas de impacto físico, psicológico e social. A relação da respiração bucal com os distúrbios respiratórios obstrutivo do sono (DROS) é proveniente de condições clínicas que variam em gravidade crescente desde o ronco primário, a síndrome da resistência da via aérea superior até a síndrome da apneia obstrutiva do sono. A principal causa da respiração bucal e dos DROS está associada ao estreitamento da via aérea superior em diferentes graus. Essa associação é preocupante por apresentar repercussões clínicas imediatas e/ou tardias de distúrbios no crescimento e desenvolvimento craniofacial, alterações do comportamento, prejuízo do aprendizado e de funções cognitivas, influenciando negativamente a qualidade de vida. Objetivo: Verificar a prevalência de escolares respiradores bucais (RB) e a presença de alterações faciais comuns em crianças que apresentam DROS, além de avaliar a autopercepção da qualidade de vida. Metodologia: Estudo transversal, observacional com amostra de 687 escolares, na faixa etária de 6 a 12 anos de idade, matriculados em escolas municipais de ensino fundamental de Vitória, ES, avaliados através de anamnese, exame clínico e testes de permanência de selamento labial. O questionário de qualidade de vida do respirador bucal (Ribeiro, 2006) foi empregado para verificar a autopercepção da qualidade de vida dos escolares diagnosticados com respiração bucal. Resultados: Na amostra total, 520 (75,7%) escolares foram classificados como respiradores nasais (RN) e 167 como RB (24,3%). Dentre os RB, 40,1% apresentaram hipertrofia obstrutiva das tonsilas palatinas, 26,4% apresentaram índice de Mallampati graus III e IV e más oclusões como: sobressaliência exagerada (35,3%), mordida aberta anterior (23,4%), mordida cruzada posterior (15,6%), palato atrésico (53,9%), ausência de selamento labial (35,9%); além de 31% terem relatado problemas relativos ao sono e 9% relataram ter a sensação de parar de respirar enquanto dormia. Conclusão: A prevalência de alterações faciais anatômicas e funcionais nos RB foi elevada, entretanto a autopercepção da qualidade de vida foi considerada boa. Recomenda-se a adoção de políticas de saúde publica visando diagnóstico, orientação e tratamento de escolares nessa faixa etária, na qual o alivio dos sinais e sintomas proporciona o crescimento normal das estruturas craniofaciais e reduz os riscos de DROS no futuro
Klein, Cristini. "Associação entre distúrbios respiratórios do sono, estresse oxidativo e doença arterial coronariana." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2010. http://hdl.handle.net/10183/24074.
Full textINTRODUCTION: Evidences suggest association between Coronary Artery Disease (CAD) and Sleeping Disordered Breathing (SDB), however the mechanism is uncertain. Repetitive episodes of hypoxia and reoxygenation experienced by individuals with SDB lead to an increase of Reactive Oxygen Species (ROS). ROS inside the erythocytes may be scavenging by glutathione peroxidase antioxidants enzymes (GPx), catalase (CAT) and superoxide dismutase (SOD). In the cytoplasm ROS may be inhibited by vitamin C, or uric acid. Oxidative stress is characterized by an unbalance between ROS and antioxidants. These unbalance promotes oxidative damage in biomolecules, this mechanism is associated to the CAD physiopathology . OBJECTIVE: Verify the relation between apnea hypopnea index (AHI) and CAD. Verify association between AHI, CAD and antioxidants enzymes activity: SOD, CAT, GPx and non enzymatic antioxidants, uric acid, and vitamin C. Evalute the relation between AHI, CAD and oxidative damage products in lipids and proteins. Among the oxidative stress markers identify the predictors for CAD. MATERIALS AND METHODS: Cross sectional study. Between June and May 2008 in the hemodinamic ward of Clinicas Hospital of Porto Alegre, we consecutively screened 519 individuals sent for diagnostic or therapeutic angiography. We included 14 cases with CAD (≥ 50% narrowing of coronary lumen) and 30 controls with < 50% narrowing. The AHI was measured by portable polisomnography. We found the presence of CAD through coronary angiography. Carbonyl groups quantification in the hemolysed and plasma and antioxidants enzyme activities of SOD, CAT and GPx were verified by spectophotometric method. Malondyaldeyde (MDA) and vitamin C were measured by HPLC. RESULTS: This work is the first one that shows correlation between AHI and increased erythrocytes protein carbonylation. In the same way evidences that individuals with significant CAD compared to controls present higher levels of carbonyl groups in the hemolysates. In a multivaried regression model adjusted to age, gender and body mass index to verify predictors for CAD, we verified that the carbonyl unit increased 1.7% the risk for development of CAD, while one unit of IAH increased in 3.9% the risk to develop CAD. We did not find correlation between AHI and the markers MDA, plasma carbonyl and the antioxidants: SOD, CAT, GPx vitamin C and uric acid. We didn’t verify correlation between CAD and the markers MDA, plasma carbonyl and the others antioxidants SOD, CAT , GPx and uric acid. Patients with significant CAD had lower levels of vitamin C. Positive correlation was observed between vitamin C and erythrocyte carbonyl concentration. CONCLUSION: We evidenced that erythrocytes protein carbonylation and AHI are important in the physiopathology of CAD. In the same way vitamin C appears important factor in CAD prevention.
Vanbuis, Jade. "Analyse automatique des stades du sommeil à partir des voies électrophysiologiques et cardiorespiratoires." Thesis, Le Mans, 2021. http://cyberdoc-int.univ-lemans.fr/Theses/2021/2021LEMA1004.pdf.
Full textThe diagnostic of sleep-disordered breathing requires the analysis of various signals obtained while recording sleep. The analysis is carried by a sleep specialist, which studies the patient's ventilation and, depending on the diagnostic tool used for the record, sleep stages. Sleep stage scoring is a complex and time-consuming task. Three diagnosis support algorithms dedicated to this task are presented in this thesis.The first one provides a wakefulness versus sleep classification, designed for a new diagnostic tool. It results in the ability to make a precise diagnosis of sleep apnea syndrome, at low cost.The second algorithm, based on electrophysiological channels, provides a full sleep stage classification while using the most complete diagnosis tool. It was implemented considering the known limitations for the use of algorithms in clinical practice. Its architecture thus reproduces the manual scoring process. A self-adaptative thresholding function was also implemented to provide a patient-dependent classification. The obtained results are comparable with the ones from sleep experts.The third algorithm, based on cardio-respiratory channels, provides a sleep stage classification while using a diagnostic tool that is insufficient for a manual sleep scoring, yet still highly used. The task is challenging but the obtained results are satisfying compared to literature.All three algorithms, which were designed for various diagnostic tools, will help sleep experts analyzing sleep
Huang, Yu-Shu 1964. "Sleep, sleep-disordered-breathing : cognition and prematurity." Doctoral thesis, 2017. http://hdl.handle.net/10451/34427.
Full textPrematurity leads to many handicaps, some of them are only recognized later in life and may impact the individuals for the rest of their life. The delivery date compared to the full term delivery time will be a measure of “indication of risks” of post-natal handicap risk, but this is only one of the many measurements that can be looked at. Many studies have investigated development of premature infants, based on different criteria at entry in the considered study. Our investigations are only a limited contribution to the investigation of premature infants. We included infants born as young as 24 weeks of gestational-age [GA] but none of the infants had major neurological syndromes recognized at birth. “Normal infants” defined as infants with more than 37 weeks of GA, birth-weight >2500g and absence of any indication of health problems born in the same hospital maternity at same time as premature infants were also recruited to serve as normal controls. As most newborn infants spend a large amount of time asleep, all the presented studies include investigation of sleep, and once sleep-time occurred mostly during the nocturnal period, it focused on the polygraphic monitoring of the nocturnal sleep. The premature cohort study was a longitudinal study and parents who signed informed consent approved by the Chang Gung Hospital and Medical College Ethic Committee, were asked to come back on a yearly basis for at least 5 years. This is an on-going study and not every child has been followed for such time. Furthermore, as in any longitudinal study, loss of patients occurred as parents did not bring children back. At entry 400 parents signed the informed consent, currently at 5 years follow-up 150 children have ended the follow-up period and about 215 at 4 years. The sample is a non-random convenience sample of children selected based on the parents` willingness to participate in the protocol and obtained with the help of neonatologist physicians in our NICUs. Most of the studies presented in the thesis come-out of this longitudinal study. The studies asked specific questions, particularly looking at development of abnormal obstructive breathing during sleep. But some of our studies looked also at children of older age as some of the findings that we observed in our premature cohort needed a different investigative approach, and prior validation on older children-premature and in non-premature infants. We have included these studies in our narrative as they become part of our research, and they are part of a general research program on “sleep- breathing-and-cognition” in children.