Relevant bibliographies by topics / Sleep apnea, obstructive

Academic literature on the topic 'Sleep apnea, obstructive'

Author: Grafiati
Published: 4 June 2021
Last updated: 20 February 2023

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Journal articles on the topic "Sleep apnea, obstructive"

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Sisniega, Carlos, and Umakanth Katwa. "Children with Upper Airway Dysfunction: At Risk of Obstructive Sleep Apnea." Journal of Child Science 09, no. 01 (January 2019): e59-e67. http://dx.doi.org/10.1055/s-0039-1688956.

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AbstractObstructive sleep apnea is characterized by prolonged partial upper airway obstruction or intermittent complete obstruction that disrupts normal ventilation during sleep and alters normal sleep patterns. Patients with obstructive sleep apnea tend to develop neurocognitive, cardiovascular, behavioral, attention issues, and poor academic performance. Therefore, it is essential to diagnose and treat obstructive sleep apnea early and avoid significant and long-lasting adverse outcomes. Most commonly, upper airway obstruction is caused by enlarged lymphoid tissues within the upper airway, and therefore adenotonsillectomy is considered as the first-line treatment of obstructive sleep apnea in children. Fifty to 70% of patients who have obstructive sleep apnea and treated by surgery are not entirely cured on follow-up polysomnography. In light of this, it is recommended that patients with suspected obstructive sleep apnea undergo a thorough evaluation, and all potential risk factors are identified and treated. The purpose of this review is to familiarize pediatricians with developmental, anatomical, and physiological risk factors involved in the development of obstructive sleep apnea. Additionally, we will present an array of evaluation techniques that can offer adequate assessment of the patient's upper airway anatomy and physiology.
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Khan, Muhammad Talha, and Rose Amy Franco. "Complex Sleep Apnea Syndrome." Sleep Disorders 2014 (2014): 1–6. http://dx.doi.org/10.1155/2014/798487.

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Complex sleep apnea is the term used to describe a form of sleep disordered breathing in which repeated central apneas (>5/hour) persist or emerge when obstructive events are extinguished with positive airway pressure (PAP) and for which there is not a clear cause for the central apneas such as narcotics or systolic heart failure. The driving forces in the pathophysiology are felt to be ventilator instability associated oscillation in PaCO2arterial partial pressure of Carbon Dioxide, continuous cositive airway pressure (CPAP) related increased CO2carbon dioxide elimination, and activation of airway and pulmonary stretch receptors triggering these central apneas. The prevalence ranges from 0.56% to 18% with no clear predictive characteristics as compared to simple obstructive sleep apnea. Prognosis is similar to obstructive sleep apnea. The central apnea component in most patients on followup using CPAP therap, has resolved. For those with continued central apneas on simple CPAP therapy, other treatment options include bilevel PAP, adaptive servoventilation, permissive flow limitation and/or drugs.
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McGinley, Brian M., Alan R. Schwartz, Hartmut Schneider, Jason P. Kirkness, Philip L. Smith, and Susheel P. Patil. "Upper airway neuromuscular compensation during sleep is defective in obstructive sleep apnea." Journal of Applied Physiology 105, no. 1 (July 2008): 197–205. http://dx.doi.org/10.1152/japplphysiol.01214.2007.

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Obstructive sleep apnea is the result of repeated episodes of upper airway obstruction during sleep. Recent evidence indicates that alterations in upper airway anatomy and disturbances in neuromuscular control both play a role in the pathogenesis of obstructive sleep apnea. We hypothesized that subjects without sleep apnea are more capable of mounting vigorous neuromuscular responses to upper airway obstruction than subjects with sleep apnea. To address this hypothesis we lowered nasal pressure to induce upper airway obstruction to the verge of periodic obstructive hypopneas (cycling threshold). Ten patients with obstructive sleep apnea and nine weight-, age-, and sex-matched controls were studied during sleep. Responses in genioglossal electromyography (EMGGG) activity (tonic, peak phasic, and phasic EMGGG), maximal inspiratory airflow (VImax), and pharyngeal transmural pressure (PTM) were assessed during similar degrees of sustained conditions of upper airway obstruction and compared with those obtained at a similar nasal pressure under transient conditions. Control compared with sleep apnea subjects demonstrated greater EMGGG, VImax, and PTM responses at comparable levels of mechanical and ventilatory stimuli at the cycling threshold, during sustained compared with transient periods of upper airway obstruction. Furthermore, the increases in EMGGG activity in control compared with sleep apnea subjects were observed in the tonic but not the phasic component of the EMG response. We conclude that sustained periods of upper airway obstruction induce greater increases in tonic EMGGG, VImax, and PTM in control subjects. Our findings suggest that neuromuscular responses protect individuals without sleep apnea from developing upper airway obstruction during sleep.
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Fairbanks, David W., and David N. F. Fairbanks. "Neurostimulation for Obstructive Sleep Apnea: Investigations." Ear, Nose & Throat Journal 72, no. 1 (January 1993): 52–57. http://dx.doi.org/10.1177/014556139307200111.

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Neurostimulation of the upper airway muscles (accessory muscles of respiration) was accomplished in anesthetized dogs and sleeping humans by electrical stimulation of the hypoglossal nerves. Such stimulations relieved partial airway obstructions in dogs. They also aborted (shortened) obstructive sleep apnea events in humans who suffer with obstructive sleep apnea syndrome. In one subject, stimulations delivered in advance of apneic events (by automatic cycling) prevented apneas. Neurostimulation for obstructive sleep apnea may be an important concept for future research and development.
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Basner, R. C., E. Onal, D. W. Carley, E. J. Stepanski, and M. Lopata. "Effect of induced transient arousal on obstructive apnea duration." Journal of Applied Physiology 78, no. 4 (April 1, 1995): 1469–76. http://dx.doi.org/10.1152/jappl.1995.78.4.1469.

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Six untreated male patients (age 19–55 yr) with obstructive sleep apnea underwent nocturnal polysomnography with acoustic stimulation to determine the effect of transient arousal on obstructive apneas during sleep. Binaural tone bursts (25–95 dB) were delivered in late expiration during the second obstructive apnea of a cycle consisting of four consecutive apneas. For the group, stimulated apneas were significantly shorter (P < 0.05, Fisher's protected least significant difference test) than were the unstimulated apneas when transient electrocortical arousal was elicited in both non-rapid-eye-movement (non-REM) sleep [mean 17 +/- 7 (SD) vs. 26 +/- 9, 23 +/- 10, and 26 +/- 12 s for 2nd vs. 1st, 3rd, and 4th apnea, respectively, of each cycle] and REM sleep (mean 19 +/- 10 vs. 35 +/- 15, 45 +/- 18, and 39 +/- 20 s). Without electrocortical arousal, the stimulated apnea was significantly shortened in non-REM (23 +/- 9 vs. 25 +/- 7, 24 +/- 8, and 26 +/- 8 s) but not in REM (32 +/- 16 vs. 37 +/- 12, 32 +/- 15, and 30 +/- 16 s). Tones delivered relatively early and late in the apnea were equally likely to be associated with resolution of the apnea. The nadir of arterial oxygen saturation of hemoglobin was inversely proportional to apnea length, with higher saturation nadirs associated with the stimulated apneas. These data indicate that transient arousal, induced by nonrespiratory stimulation, influences the resolution of obstructive apneas during sleep.
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Durgan, David J., Randy F. Crossland, and Robert M. Bryan. "The rat cerebral vasculature exhibits time-of-day-dependent oscillations in circadian clock genes and vascular function that are attenuated following obstructive sleep apnea." Journal of Cerebral Blood Flow & Metabolism 37, no. 8 (January 1, 2016): 2806–19. http://dx.doi.org/10.1177/0271678x16675879.

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Circadian clock components oscillate in cells of the cardiovascular system. Disruption of these oscillations has been observed in cardiovascular diseases. We hypothesized that obstructive sleep apnea, which is associated with cerebrovascular diseases, disrupts the cerebrovascular circadian clock and rhythms in vascular function. Apneas were produced in rats during sleep. Following two weeks of sham or obstructive sleep apnea, cerebral arteries were isolated over 24 h for mRNA and functional analysis. mRNA expression of clock genes exhibited 24-h rhythms in cerebral arteries of sham rats (p < 0.05). Interestingly, peak expression of clock genes was significantly lower following obstructive sleep apnea (p < 0.05). Obstructive sleep apnea did not alter clock genes in the heart, or rhythms in locomotor activity. Isolated posterior cerebral arteries from sham rats exhibited a diurnal rhythm in sensitivity to luminally applied ATP, being most responsive at the beginning of the active phase (p < 0.05). This rhythm was absent in arteries from obstructive sleep apnea rats (p < 0.05). Rhythms in ATP sensitivity in sham vessels were absent, and not different from obstructive sleep apnea, following treatment with L-NAME and indomethacin. We conclude that cerebral arteries possess a functional circadian clock and exhibit a diurnal rhythm in vasoreactivity to ATP. Obstructive sleep apnea attenuates these rhythms in cerebral arteries, potentially contributing to obstructive sleep apnea-associated cerebrovascular disease.
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Mattiuzzi, Camilla, Massimo Franchini, and Giuseppe Lippi. "Sleep apnea and venous thromboembolism." Thrombosis and Haemostasis 114, no. 11 (2015): 958–63. http://dx.doi.org/10.1160/th15-03-0188.

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SummaryRecent evidence suggests that obstructive sleep apnea is a significant and independent risk factor for a number of cardiovascular disorders. Since the association between obstructive sleep apnea and cardiovascular disease is mediated by endothelial dysfunction, hypercoagulability and platelet abnormalities, we sought to investigate whether sleep apnea may also be considered a risk factor for venous thromboembolism (VTE). We carried out an electronic search in Medline and Scopus using the keywords “apnea” OR “apnoea” AND “venous thromboembolism” OR “deep vein thrombosis” OR “pulmonary embolism” in “Title/Abstract/Keywords”, with no language or date restriction. Fifteen studies (8 case-control, 4 retrospective observational, 2 prospective case-control and 1 prospective observational) were finally selected for this systematic review. In all studies except one (14/15; 93%), obstructive sleep apnea was found to be an independent risk factor for VTE, either deep-vein thrombosis (DVT) or pulmonary embolism (PE). In the two prospective case-control studies the risk of DVT or PE was found to be two-to three-fold higher in patients with obstructive sleep apnea than in those without. In conclusion, the current epidemiological evidence supports the hypothesis that obstructive sleep apnea may be an independent risk factor for VTE.
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Bhandarkar, Dr Ajay M., Dr Rukma Bhandary, and Dr Suraj S. Nair. "Clinical Indicators of Obstructive Sleep Apnea Syndrome." International Journal of Scientific Research 2, no. 12 (June 1, 2012): 399–400. http://dx.doi.org/10.15373/22778179/dec2013/120.

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Bilińska, Małgorzata, and Kazimierz Niemczyk. "Hypoglossal nerve stimulation [HGNS] for Obstructive Sleep Apnea [OSA] treatment – a review." Polski Przegląd Otorynolaryngologiczny 6, no. 3 (September 30, 2017): 66–71. http://dx.doi.org/10.5604/01.3001.0010.5196.

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Obstructive sleep apnea (OSA) is characterized by recurrent periods of upper airway obstruction (hypopneas and apneas) during sleep. It leads to repeated oxyhemoglobin desaturations, nocturnal hypercapnia, and arousals. Common symptoms include loud snoring with breathing interruptions. Excessive daytime sleepiness and cognitive impairment occur. Obstructive sleep apnea is a major cause of morbidity and mortality in Western society. Its association with an increased risk of development and progression of neurocognitive, metabolic, cardiovascular and oncologic diseases and complications is well described. The significant factor in OSA pathogenesis is reduced muscle tone in the tongue and upper airway. In the recent years, devices providing neurostimulation of the hypoglossal nerve (HGNS) were developed as an alternative for noncompliant CPAP (continuous positive airway pressure) patients. Clinical trials suggest that electrical stimulation of the hypoglossal nerve is effective. This is considered to be one of the targets of neurostimulation in the treatment of obstructive sleep apnea (OSA).
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Hanly, Patrick J., and David Ford. "Sleep Apnea and Aortic Dissection." Canadian Respiratory Journal 2, no. 1 (1995): 69–73. http://dx.doi.org/10.1155/1995/254831.

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A 62-year-old man presented with obstructive sleep apnea, congestive heart failure and Cheyne-Stokes respiration. Further evaluation revealed a chronic dissecting aneurysm of the aorta causing vena caval obstruction. Surgical correction or the aneurysm dramatically improved ventricular function with resolution of Cheyne-Stokes respiration. Nasal continuous positive airway pressure corrected the obstructive sleep apnea and associated clinical features. The cardiopulmonary interactions between sleep apnea and aortic dissection are discussed.
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Dissertations / Theses on the topic "Sleep apnea, obstructive"

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Lam, Chung-mei Jamie, and 林頌眉. "Obstructive sleep apnea and cardiometabolic complications." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43085854.

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Mariscal, Norma Linda, and Norma Linda Mariscal. "Management of Postoperative Obstructive Sleep Apnea." Diss., The University of Arizona, 2017. http://hdl.handle.net/10150/624558.

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Background: Obstructive sleep apnea (OSA) is a sleep disorder characterized by episodes of cessation of breathing (apnea) during sleep. Unfortunately, a significant number of surgical patients are unaware they are afflicted with this disorder increasing the risks of postoperative complications. The lingering effect of general anesthesia causes an increase in frequency of airway collapse, leading to longer periods of apnea. This increasingly common sleep disorder is concerning for many anesthesia providers. Purpose: The purpose of this study was to evaluate the anesthesia provider's knowledge and postoperative management of patients with suspected or diagnosed OSA. Setting: The study setting was a local urban hospital Mountain Vista Medical Center (MVMC) in Gilbert, AZ. The study included (N=7) participants, who were predominantly male (85%) and a majority of the participants were Master’s prepared (85%) anesthesia providers. Method: An online survey was disseminated to participants via email. The survey included questions regarding the anesthesia provider's knowledge and postoperative practice habits of patients with suspected or diagnosed OSA at MVMC. Results: The response rate was (24%). All the respondents acknowledged that OSA was a risk factor for postoperative complications. Over half of the respondents (85%) reported encountering postoperative complications such as desaturation and apnea in their patients with OSA. The main complication that was encountered was postoperative apnea (50%), followed by decreased in saturations (33.33%), and one respondent (16.67%) encountered re-intubation during the postoperative period. However, the most important finding of the study is that over half of the providers did not routinely include continued positive airway pressure (CPAP)/noninvasive positive pressure ventilation (NIPPV) in their postoperative management of patients with suspected or known OSA due to the time needed to initiate the therapy. Conclusion: The study illustrates that a majority of anesthesia providers at MVMC agreed OSA is a significant risk factor for postoperative complications, but time constraints limited the implementation of noninvasive ventilation (NIV) therapies. Recommended strategies would be to establish a task force to examine this barrier to therapy and develop plans to address it.
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Lam, Chung-mei Jamie. "Obstructive sleep apnea and cardiometabolic complications." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B43085854.

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Wimms, Alison Jane. "Gender Differences in Obstructive Sleep Apnea." Thesis, The University of Sydney, 2019. https://hdl.handle.net/2123/21632.

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The overall aim of this thesis was to understand gender differences in obstructive sleep apnea (OSA) and use this information to develop a tailored therapy for female patients. Specific aims were to determine whether gender differences commonly reported in the literature are present in mild OSA and upper airway resistance syndrome (UARS) patient groups, and whether symptoms could be linked to respiratory parameters in these groups. The final aim was to develop, test and validate a new AutoSet treatment for female OSA patients. CHAPTER 1 of this thesis provides a detailed review of gender differences in the prevalence, symptoms, clinical experience, and health outcomes of OSA and UARS patients, with a focus on the implications of different scoring rules. CHAPTER 2 reviews of quality of life questionnaires from 259 untreated patients with mild OSA. Females reported statistically significantly higher levels of sleepiness, fatigue, insomnia, and anxiety/depression compared to males. CHAPTER 3 of this thesis reviews polygraphy data from patients with mild OSA. Male patients were found to have significantly more breathing disturbances than females, however many of these difference disappeared when updated scoring criteria were used. Some weak correlations were found between respiratory parameters and symptoms; however, no clear conclusions could be drawn. CHAPTER 4 outlines the development of a new AutoSet device designed for female- specific breathing patterns. The remaining chapters (CHAPTER 5, and CHAPTER 6) of this thesis describe the testing and validation activities undertaken on the AutoSet F, including a clinical trial to test efficacy; a bench test to compare performance against other commercially available devices; a controlled product launch to validate the features of the algorithm; and finally a clinical trial which demonstrated improvements in sleep efficacy and quality of life over a three-month usage period. In summary, this thesis has shown that at the mild end of the OSA spectrum females are more symptomatic than males, even though respiratory differences in the genders are less pronounced than those described in moderate-to-severe patients. An AutoSet designed specifically for female OSA patients was successful in demonstrating efficacy and clinical effectiveness.
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Ulander, Martin. "Psychometric aspects of obstructive sleep apnea syndrome." Doctoral thesis, Linköpings universitet, Avdelningen för neurovetenskap, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-97475.

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Introduction: Obstructive sleep apnea (OSA) is a common chronic disorder consisting of episodes with impaired breathing due to obstruction of the upper airways. Treatment with Continuous Positive Airway Pressure (CPAP) is a potentially effective treatment, but adherence is low. Several potential factors affecting adherence, e.g., subjective sleepiness and personality, are only quantifiable through questionnaires. Better knowledge about psychometric properties of such questionnaires might improve future research on CPAP adherence and thus lead to better treatment options. Aim: Study I: To describe the devlopment and initial testing of the Side Effects of CPAP treatment Inventory (SECI) questionnaire. Study II: To describe the prevalence of Type D personality in OSAS patients with CPAP treatment longer than 6 months and the association with self-reported side effects and adherence. Study III: To study whether any of the items in the Epworth Sleepiness Scale (ESS) exhibit differential item functioning and, if so, to which degree. Study IV: To examine the evolution of CPAP side effects over time; and prospectively assess correlations between early CPAP side effects and treatment adherence. Patients and Methods: In study I, SECI items were based on a literature review, an expert panel and interviews with patients. It was then mailed to 329 CPAP-treated OSAS patients. Based on this, a principal component analysis was performed, and SECI results were compared between adherent and non-adherent patients. In study II, the population consisted of 247 OSAS patients with ongoing CPAP treatment. The DS14 was used to assess the prevalence of type D personality, and SECI and adherence data from medical records were used to correlate Type D personality to side effects and adherence. In study III, the population consisted of pooled data from 1,167 subjects who had completed the ESS in five other studies. Ordinal regression and Rasch analysis were used to assess the existence of differential item functioning for age and gender. The cutoff for age was 65 years in the Rasch analysis. In study IV, SECI was sent to 186 subjects with newly diagnosed OSAS three times during the first year on CPAP. SECI results were followed over time within subjects, and were correlated to treatment dropout during the first year and machine usage time after 6 months. Results: SECI provides a valid and reliable instrument to measure side effects, and non-adherent patients have higher scores (i.e., were more bothered by side effects) than adherent patients (study I). Type D personality was prevalent in approximately 30 % of CPAP treated OSAS patients, and was associated to poorer objective and subjective adherence as well as more side effects (study II). Differential item functioning was present in items 3, 4 and 8 for age in both DIF analyses, and to gender in item 8 the Rasch analysis (study III). Dry mouth and increased number of awakenings were consistently associated to poorer adherence in CPAP treated patients. Side effects both emerged and resolved over time (study IV). Conclusions: Differences in previous research regarding side effects and CPAP adherence might be explained by differences in how side effects and adherence are defined. While some side effects are related to adherence, others are not. Side effects are furthermore not stable over time, and might be related to personality. ESS scores are also related to CPAP adherence according to previous research, but might be affected by other factors than sleepiness, such as age and possibly gender.
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Lee, Kevin Chien-Hsun. "Dentofacial morphology in children with obstructive sleep apnea." Thesis, University of British Columbia, 2015. http://hdl.handle.net/2429/54507.

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Objectives: Altered dentofacial morphology has been suggested as an etiology for childhood OSA. Nevertheless, existing reports on the dentofacial characteristics of children with OSA vary significantly and are limited by the infrequent use of polysomnography (PSG) for diagnosis. Therefore, the objective of this study is to establish the prevalence of dentofacial morphology in children with OSA diagnosed using PSG. Methods: The sample comprised 64 children between the ages of 4-16 who were referred to BC Children’s Hospital for PSG. Diagnosis of OSA was provided by an overnight, in-laboratory PSG. Malocclusion was assessed clinically by one orthodontist (K.L.), blinded to PSG results. Results: Children with previous orthodontic treatment were excluded and children with craniofacial syndromes were analyzed separately. The 17 patients with craniofacial syndromes presented a significantly different dentofacial features and higher prevalence of OSA when compared to the non-syndromic children. The remaining 39 patients were divided into an OSA group (AHI ≥ 2; n=17) and a non-OSA group (AHI < 2; n=22). There were no statistically significant differences in frequency of any dentofacial features between the two groups, although the OSA group had a lower prevalence of convex profile, Class II molar relationship, and overjet (OJ) ≥ 5mm. Subjects in the OSA group were further divided into a lower AHI (AHI between 2-5; n=9) group and a higher AHI group (AHI ≥ 5; n=8). There was no statistically significant difference in frequency of any dentofacial features between the three groups. Nevertheless, subjects in the higher AHI group had a lower prevalence of convex profile and poster crossbite, with less crowding and smaller OJ on average. Conclusions: In this patient population of 39 children between the ages of 4-16 who were referred to BCCH for an overnight sleep study, no statistically significant differences in dentofacial morphology and occlusal characteristics were found between children diagnosed with and without OSA. It is likely that children with OSA have a highly variable presentation of anatomical features, and future studies with a larger sample size and a true control group is needed to establish the dentofacial morphology of this population.
Dentistry, Faculty of
Graduate
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Kalra, Maninder. "Genetic Susceptibility to Obstructive Sleep Apnea in Children." University of Cincinnati / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1226552538.

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Aihara, Kensaku. "Local and systemic inflammation in obstructive sleep apnea." Kyoto University, 2013. http://hdl.handle.net/2433/170073.

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Gagnon, Victoria Lee. "Obstructive sleep apnea syndrome and associated health risks /." Abstract Full Text (HTML) Full Text (PDF), 2008. http://eprints.ccsu.edu/archive/00000538/02/1986FT.htm.

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Thesis (M.S.) -- Central Connecticut State University, 2008.
Thesis advisor: Ruth Rollin. "... in partial fulfillment of the requirements for the degree of Master of Science in Biology." Includes bibliographical references (leaves 39-41). Also available via the World Wide Web.
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Huhtakangas, J. (Jaana). "Evolution of obstructive sleep apnea after ischemic stroke." Doctoral thesis, Oulun yliopisto, 2019. http://urn.fi/urn:isbn:9789526224343.

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Abstract In Finland, the costs of stroke are approximately 1.1 billion euros annually due to long disability and hospitalization episodes. Sleep apnea is a risk factor for stroke. The prevalence of sleep apnea among stroke patients is unknown because sleep recording is not usually performed on stroke patients. There are no previous studies investigating the association of thrombolysis on the prognosis of sleep apnea. The relation between sleep apnea and cardiovascular events is still unclear. In this prospective, observational study, I recruited voluntary, consecutive ischemic stroke patients over the age of 18 years who were or were not eligible for thrombolysis treatment. The investigators did not affect the treatment and patients were not randomized to thrombolysis. The final analysis included 204 patients; of these, 110 underwent thrombolysis therapy and 94 were treated without thrombolysis. Cardiorespiratory polygraphy was carried out with a portable three-channel device (ApneaLinkPlus™, Resmed, Sydney, Australia) at the ward within 48 hours after the onset of stroke symptoms. The cardiorespiratory polygraphy was repeated at home after a six-month follow-up. Both automatic scoring and manual scoring pointed out excellent agreement in arterial oxyhemoglobin decrease of > 4% (ODI4), lowest arterial oxyhemoglobin saturation (SaO2) or percentage of time spent below 90 percent saturation. The automated scoring underestimated the severity of sleep apnea, recognized poorly the type of event, and missed 18.6% of sleep apnea diagnoses. The total prevalence of sleep apnea in this study was 91.2% on admission to hospital. The stroke patients treated with thrombolysis had more, and more severe sleep apnea in the first sleep recording compared to those without thrombolysis therapy. After follow-up, the prevalence of sleep apnea still remained high, and sleep apnea was aggravated in two thirds of the stroke patients. The study patients without thrombolysis treatment had six-fold higher risk for incident sleep apnea after the follow-up. The stroke patients with thrombolysis therapy and visible stroke on CT had more nocturnal hypoxemia and higher obstructive apnea index than the patients without stroke lesion on follow-up CT 24 hours after thrombolysis treatment. The larger the ischemic stroke volume, the greater the time spent with saturation below 90%
Tiivistelmä Aivoinfarkti on yleinen ja kansanterveydellisesti sekä taloudellisesti merkittävä sairaus, jonka aiheuttamat kustannukset Suomessa ovat noin 1.1 miljardia euroa pitkistä työkyvyttömyys- ja sairaalajaksoista johtuen. Uniapnea on aivoinfarktille altistava tekijä. Uniapnean esiintyvyys suomalaisilla aivoinfarktipotilailla ei ole arvioitavissa, koska aivoinfarktin sairastaneille ei yleensä tehdä unirekisteröintiä. Kannettavat yöpolygrafialaitteet saattaisivat olla vaihtoehto aivoinfarktipotilaiden uniapnean diagnosoinnille. Tutkittua tietoa liuotushoidon yhteydestä uniapnean ennusteeseen ei ole. Uniapnean sekä sydän- ja verisuonitapahtumien syy-yhteys on edelleen epäselvä. Rekrytoin prospektiiviseen tutkimukseeni vapaaehtoisia, peräkkäisiä yli 18-vuotiaita iskeemiseen aivoinfarktiin sairastuneita liuotushoidettuja ja liuotushoitoon soveltumattomia potilaita. Tutkimuksen lopullinen potilasmäärä oli 204, joista 110 sai liuotushoidon ja 94 hoidettiin ilman liuotusta. Kaikille potilaille tehtiin yöpolygrafia kannettavalla, kolmikanavaisella yöpolygrafialaitteella (Apnealink Plus, Resmed, Sydney, Australia) osastolla 48 tunnin kuluessa sairastumisesta. Yöpolygrafia toistettiin potilaan kotona kuuden kuukauden kuluttua. Sekä automaattitulos että manuaalisesti arvioitu unirekisteröintitulos olivat erittäin yhteneväisiä, kun arvion kohteena olivat happikyllästeisyyden neljän prosenttiyksikön suuruiset pudotukset tuntia kohti, matalin veren happikyllästeisyys tai alle 90 % happikyllästeisyyden osuus yöstä. Automaattianalyysi aliarvioi uniapnean vaikeuden, havaitsi huonosti hengityskatkosten tyypin eikä löytänyt 18,6 prosenttia uniapneadiagnooseista. Uniapnean esiintyvyys koko aineistossa oli sairaalaan tullessa 91,2 %. Liuotushoidetuilla potilailla todettiin ensimmäisessä rekisteröinnissä enemmän uniapneaa ja se oli vaikeampaa kuin ei-liuotushoidetuilla. Seurannassa uniapnean määrä pysyi edelleen korkeana ja uniapnea vaikeutui kahdella potilaalla kolmesta. Liuotushoitoon soveltumattomilla aivoinfarktipotilailla todettiin liuotushoidon saaneisiin verrattuna kuusinkertainen riski sairastua uniapneaan puolen vuoden aikana. Liuotushoidetuilla aivoinfarktipotilailla, joilla oli infarktimuutos kuvantamistutkimuksessa, oli yöllistä valtimoveren happikyllästeisyyden huononemista ja ylähengitysteiden ahtautumisesta johtuvia hengityskatkoksia enemmän kuin niillä potilailla, joilla ei todettu iskeemisiä muutoksia aivokuvantamisessa 24 tuntia liuotushoidon jälkeen. Mitä suurempi aivoinfarktin tilavuus, sitä suuremman osuuden yöstä veren happikyllästeisyys oli alle 90 %
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Books on the topic "Sleep apnea, obstructive"

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Carr, Michele M. Pediatric obstructive sleep apnea. Alexandria, VA: American Academy Of Otolaryngology--Head and Neck Surgery Foundation, 2007.

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name, No. Snoring and obstructive sleep apnea. 3rd ed. Philadelphia, PA: Lippincott Willians & Wilkins, 2003.

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Kim, Ki Beom, Reza Movahed, Raman K. Malhotra, and Jeffrey J. Stanley, eds. Management of Obstructive Sleep Apnea. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-54146-0.

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de Vries, Nico, Madeline Ravesloot, and J. Peter van Maanen, eds. Positional Therapy in Obstructive Sleep Apnea. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-09626-1.

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Salman, Salam O., ed. Modern Management of Obstructive Sleep Apnea. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-11443-5.

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Kim, Su-Jung, and Ki Beom Kim, eds. Orthodontics in Obstructive Sleep Apnea Patients. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-24413-2.

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Woodson, B. Tucker. Obstructive sleep apnea syndrome: Diagnosis and treatment. Alexandria, VA: American Academy of Otolaryngology--Head and Neck Surgery Foundation, 1996.

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Deenadayal, D. S., and Vyshanavi Bommakanti. Management of Snoring and Obstructive Sleep Apnea. Singapore: Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-6620-9.

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Heiser, Clemens, and Nico de Vries, eds. Upper Airway Stimulation in Obstructive Sleep Apnea. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-89504-4.

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Vicini, Claudio, Paul T. Hoff, and Filippo Montevecchi, eds. TransOral Robotic Surgery for Obstructive Sleep Apnea. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-34040-1.

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Book chapters on the topic "Sleep apnea, obstructive"

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De Backer, W. "Obstructive Sleep Apnea-Hypopnea Syndrome." In Sleep Apnea, 90–96. Basel: KARGER, 2006. http://dx.doi.org/10.1159/000093150.

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Atwood, Charles W. "Obstructive Sleep Apnea." In Primary Care Sleep Medicine, 89–95. Totowa, NJ: Humana Press, 2007. http://dx.doi.org/10.1007/978-1-59745-421-6_8.

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Friedewald, Vincent E. "Obstructive Sleep Apnea." In Clinical Guide to Cardiovascular Disease, 949–61. London: Springer London, 2016. http://dx.doi.org/10.1007/978-1-4471-7293-2_71.

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Won, Christine, Jee Hyun Kim, and Christian Guilleminault. "Obstructive Sleep Apnea." In International Neurology, 563–65. Oxford, UK: Wiley-Blackwell, 2010. http://dx.doi.org/10.1002/9781444317008.ch145.

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Niemiec, Linda, and Lewis J. Kass. "Obstructive Sleep Apnea." In Nursing Care in Pediatric Respiratory Disease, 247–68. West Sussex, UK: John Wiley & Sons Inc., 2013. http://dx.doi.org/10.1002/9781118785805.ch9.

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Jensen, Chad D., Amy F. Sato, Elissa Jelalian, Elizabeth R. Pulgaron, Alan M. Delamater, Chad D. Jensen, Amy F. Sato, et al. "Obstructive Sleep Apnea." In Encyclopedia of Behavioral Medicine, 1363. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-1005-9_101177.

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Patel, Janesh, and Christian Guilleminault. "Obstructive sleep apnea." In International Neurology, 610–12. Chichester, UK: John Wiley & Sons, Ltd, 2016. http://dx.doi.org/10.1002/9781118777329.ch151.

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Kanarek-Kucner, Joanna, Jacek Wolf, and Krzysztof Narkiewicz. "Obstructive Sleep Apnea." In Secondary Hypertension, 149–58. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-45562-0_10.

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Shams, Medhat, and Hayam AlTaweel. "Obstructive Sleep Apnea." In Textbook of Clinical Otolaryngology, 585–92. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-54088-3_51.

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de Silva, Bertrand R. "Obstructive Sleep Apnea." In Controversies in Obesity, 145–49. London: Springer London, 2013. http://dx.doi.org/10.1007/978-1-4471-2834-2_18.

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Conference papers on the topic "Sleep apnea, obstructive"

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Jaradat, O., A. Osenga, G. Anders, and L. Olson. "Obstructive Sleep Apnea Screening." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a4149.

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Manukyan, Aikush S., Irina V. Muzychenko, Tamara S. Popova, Elena A. Khomenko, and Tatiana A. Kosenchuk. "Obstructive sleep apnea syndrome." In Актуальные вопросы оториноларингологии. Благовещенск: Амурская государственная медицинская академия, 2022. http://dx.doi.org/10.22448/9785604863312_167.

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Hamnvik, Sondre, Pierre Bernabé, and Sagar Sen. "Yolo4Apnea: Real-time Detection of Obstructive Sleep Apnea." In Twenty-Ninth International Joint Conference on Artificial Intelligence and Seventeenth Pacific Rim International Conference on Artificial Intelligence {IJCAI-PRICAI-20}. California: International Joint Conferences on Artificial Intelligence Organization, 2020. http://dx.doi.org/10.24963/ijcai.2020/754.

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Obstructive sleep apnea is a serious sleep disorder that affects an estimated one billion adults worldwide. It causes breathing to repeatedly stop and start during sleep which over years increases the risk of hypertension, heart disease, stroke, Alzheimer's, and cancer. In this demo, we present Yolo4Apnea a deep learning system extending You Only Look Once (Yolo) system to detect sleep apnea events from abdominal breathing patterns in real-time enabling immediate awareness and action. Abdominal breathing is measured using a respiratory inductance plethysmography sensor worn around the stomach. The source code is available at https://github.com/simula-vias/Yolo4Apnea
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Sesemann, L. "Bradyarrhythmias in Obstructive Sleep Apnea." In American Thoracic Society 2021 International Conference, May 14-19, 2021 - San Diego, CA. American Thoracic Society, 2021. http://dx.doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a4697.

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Yadollahi, A., and Z. Moussavi. "Acoustic obstructive sleep apnea detection." In 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2009. http://dx.doi.org/10.1109/iembs.2009.5332870.

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Liu, Juan, Qin Li, Yi Xin, and Xiao Lu. "Obstructive Sleep Apnea Detection Using Sleep Architecture." In 2020 IEEE International Conference on Mechatronics and Automation (ICMA). IEEE, 2020. http://dx.doi.org/10.1109/icma49215.2020.9233529.

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Oliveira Cabrita, Bruno Miguel, Sílvia Correia, Ana Luisa Fernandes, Cláudia Coelho, Daniela Rodrigues, Maria Antónia Galego, Marisa Rodrigo, Paula Simão, and Jorge Ferreira. "Obstructive sleep apnea in the elderly." In ERS/ESRS Sleep and Breathing Conference 2019 abstracts. European Respiratory Society, 2019. http://dx.doi.org/10.1183/23120541.sleepandbreathing-2019.p118.

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Le, Trung Bao, and Guilherme J. M. Garcia. "Simulating Airway Collapse in Obstructive Sleep Apnea Using Fluid-Structure Interaction Methodologies." In 2018 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/dmd2018-6818.

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Obstructive Sleep Apnea (OSA) is a prevalent disease among adults and children (Macey, Woo, Kumar, Cross, & Harper, 2010). Patients with OSA have recurrent episodes of airflow limitation during sleep, which lead to daytime sleepiness and several comorbidities, including cardiovascular diseases (Durán, Esnaola, Rubio, & Iztueta, 2001). During the episode of OSA, the airway is partially occluded (hypopnoeas) or totally blocked (apneas). Since the velopharynx is the narrowest segment of the pharyngeal airway, the local air velocity increases significantly leading to the large decrease in the intraluminal pressure. The relationship between the distribution of the minimum pressure and the anatomical geometry of the airway is thus very important. Hence, understanding the mechanical interaction between the soft palate and air flow is important in investigating OSA pathology.
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Behar, Joachim A., Niclas Palmius, Jonathan Daly, Qiao Li, Fabiola Rizzatti, Lia Bittencourt, and Gari D. Clifford. "Sleep Questionnaires in Screening for Obstructive Sleep Apnea." In 2017 Computing in Cardiology Conference. Computing in Cardiology, 2017. http://dx.doi.org/10.22489/cinc.2017.233-188.

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Djonlagic, Ina, Julian P. Saboisky, Andrea Carusona, Robert Stickgold, and Atul Malhotra. "Sleep-dependent Memory Consolidation In Obstructive Sleep Apnea." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a5578.

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Reports on the topic "Sleep apnea, obstructive"

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Torres, Claudia Fernandez, and Alvaro Zubizarreta Macho. Mandibular advancement appliances to treat apnea: an update of the most used currently. A systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2022. http://dx.doi.org/10.37766/inplasy2022.11.0034.

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Review question / Objective: Mandibular advancement devices used to treat obstructive sleep apnea. Condition being studied: Obstructive sleep apnea is characterized by episodes of a complete (apnea) or partial collapse (hypopnea) of the upper airway with an associated decrease in oxygen saturation or arousal from sleep. This disturbance results in fragmented, nonrestorative sleep. Other symptoms include loud, disruptive snoring, witnessed apneas during sleep, and excessive daytime sleepiness. OSA has significant implications for cardiovascular health, mental illness, quality of life, and driving safety.
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Czerwaty, Katarzyna, Karolina Dżaman, Krystyna Maria Sobczyk, and Katarzyna Irmina Sikrorska. The Overlap Syndrome of Obstructive Sleep Apnea and Chronic Obstructive Pulmonary Disease: A Systematic Review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2022. http://dx.doi.org/10.37766/inplasy2022.11.0077.

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Review question / Objective: To provide the essential findings in the field of overlap syndrome of chronic obstructive pulmonary disease and obstructive sleep apnea, including prevalence, possible predictors, association with clinical outcomes, and severity compared to both chronic obstructive pulmonary disease and obstructive sleep apnea patients. Condition being studied: OSA is characterized by complete cessation (apnea) or significant decrease (hy-popnea) in airflow during sleep and recurrent episodes of upper airway collapse cause it during sleep leading to nocturnal oxyhemoglobin desaturations and arousals from rest. The recurrent arousals which occur in OSA lead to neurocognitive consequences, daytime sleepiness, and reduced quality of life. Because of apneas and hypopneas, patients are experiencing hypoxemia and hypercapnia, which result in increasing levels of catecholamine, oxidative stress, and low-grade inflammation that lead to the appearance of cardio-metabolic consequences of OSA. COPD is a chronic inflammatory lung disease defined by persistent, usually pro-gressive AFL (airflow limitation). Changes in lung mechanics lead to the main clini-cal manifestations of dyspnea, cough, and chronic expectoration. Furthermore, patients with COPD often suffer from anxiety and depression also, the risk of OSA and insomnia is higher than those hospitalized for other reasons. Although COPD is twice as rare as asthma but is the cause of death eight times more often.
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Torres-Castro, Rodrigo, Lilian Solis-Navarro, Homero Puppo, Roberto Vera-Uribe, Victoria Alcaraz-Serrano, and Jordi Vilaró. Respiratory muscle training in patients with obstructive sleep apnea: A systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, February 2022. http://dx.doi.org/10.37766/inplasy2022.2.0096.

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Review question / Objective: Is respiratory muscle training effective in patients with obstructive sleep apnea? Condition being studied: Effects of respiratory muscle training in patients with obstructive sleep apnea. Information sources: We included the following databases: Pubmed, CENTRAL, Web of Science, CINAHL, EMBASE, Scopus and Scielo. Additionally, the references list of the included studies will be manually reviewed.
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Hazboun, Tawfiq N. Obstructive Sleep Apnea Oral Appliance vs. Auto Titrating Positive Airway Pressure. Fort Belvoir, VA: Defense Technical Information Center, June 2013. http://dx.doi.org/10.21236/ad1012981.

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Sun, Dong, Yanan Zhang, and Di Zhou. The relationship between obstructive sleep apnea and retinal vein occlusion : a Meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, February 2022. http://dx.doi.org/10.37766/inplasy2022.2.0068.

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Lu, Jiyuan, Lingdan Xu, Yanduo Yang, Yucheng Meng, Yi Li, Huihui Wang, and Bin Liu. Obstructive sleep apnea and serum total testosterone: a system review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, March 2022. http://dx.doi.org/10.37766/inplasy2022.3.0110.

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Parthasarathy, Sairam, Stefano Guerra, Stuart F. Quan, Michael Grandner, and Patricia L. Haynes. Does a Peer Support Program Improve Satisfaction With Treatment Among Patients With Obstructive Sleep Apnea? Patient-Centered Outcomes Research Institute (PCORI), April 2020. http://dx.doi.org/10.25302/04.2020.ihs.130602505.

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Zhang, Dong, Zhi Xiang Yu, and Fu Yi. Atrial fibrillation And the Severe of Obstructive Sleep Apnea (OSA): A Dose-Response Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, December 2020. http://dx.doi.org/10.37766/inplasy2020.12.0104.

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Zhuo, Guifeng, Hengwang Yu, Ran Liao, Xuexia Zheng, Dongmin Liu, Libing Mei, and Guiling Wu. Electroacupuncture for Obstructive Sleep Apnea Hypoventilation Syndrome: A protocol for systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, April 2022. http://dx.doi.org/10.37766/inplasy2022.4.0090.

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Cao, Yanmei, Liangbin Xie, Ping Wang, and Rui Chen. The relationship between obstructive sleep apnea hypopnea syndrome and interstitial lung diseases: an uptated meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, July 2021. http://dx.doi.org/10.37766/inplasy2021.7.0085.

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