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Journal articles on the topic 'Skin Diseases Treatment Thailand'

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Author: Grafiati

Published: 10 December 2022

Last updated: 29 January 2023

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1

Saising, Jongkon, Katesarin Maneenoon, Oraphan Sakulkeo, Surasak Limsuwan, Friedrich Götz, and Supayang Piyawan Voravuthikunchai. "Ethnomedicinal Plants in Herbal Remedies Used for Treatment of Skin Diseases by Traditional Healers in Songkhla Province, Thailand." Plants 11, no. 7 (March 25, 2022): 880. http://dx.doi.org/10.3390/plants11070880.

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Skin disorders are a worldwide health problem that normally affect human life. A traditional healer is an important expert in researching notable medicinal plants for skin disease treatment. This study aimed to determine the traditional knowledge and the use of medicinal plants for the treatment of skin diseases among traditional healers in the Songkhla province, Thailand. The ethnobotanical information was collected from experienced traditional healers by semi-structured interviews and participant observations. Plant specimens were also collected and identified using the standard taxonomic method. The data were analyzed by interpretation and descriptive statistics. Twenty-five polyherbal formulations for the treatment of skin diseases were obtained from traditional healers with at least 10 years of experience. A total of 66 plant species in 38 families were documented. Leaves and trees were the most commonly employed plant parts and plant habits included in the herbal remedies, respectively. Fabaceae, Rubiaceae, and Zingiberaceae were the majority of the cited families. Oryza sativa L. and Zingiber montanum (J. Koenig) Link ex A.Dietr. were the most preferred plants combined in the prescriptions, which had the highest use value (UV = 0.83). The highest relative frequency of citation was represented by Curcuma longa L., Eurycoma longifolia Jack, Knema globularia (Lamk.) Warb, and Senna siamea (Lam.) Irwin & Barneby. (0.55 each). This research suggests the importance of traditional healers in the healing of skin diseases with herbal remedies. A variety of medicinal plants are used in the prescriptions for the treatment of skin disorders in the Songkhla province, in the south of Thailand. Pharmacological and toxicological activities as well as phytochemical constituents of polyherbal remedies should be further investigated to scientifically verify further applications of widely practiced herbal medicines.

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Brimson, James Michael, Mani Iyer Prasanth, Dicson Sheeja Malar, Sirikalaya Brimson, and Tewin Tencomnao. "Rhinacanthus nasutus “Tea” Infusions and the Medicinal Benefits of the Constituent Phytochemicals." Nutrients 12, no. 12 (December 9, 2020): 3776. http://dx.doi.org/10.3390/nu12123776.

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Rhinacanthus nasutus (L.) Kurz (Acanthaceae) (Rn) is an herbaceous shrub native to Thailand and much of South and Southeast Asia. It has several synonyms and local or common names. The root of Rn is used in Thai traditional medicine to treat snake bites, and the roots and/or leaves can be made into a balm and applied to the skin for the treatment of skin infections such as ringworm, or they may be brewed to form an infusion for the treatment of inflammatory disorders. Rn leaves are available to the public for purchase in the form of “tea bags” as a natural herbal remedy for a long list of disorders, including diabetes, skin diseases (antifungal, ringworm, eczema, scurf, herpes), gastritis, raised blood pressure, improved blood circulation, early-stage tuberculosis antitumor activity, and as an antipyretic. There have been many studies investigating the roles of Rn or compounds isolated from the herb regarding diseases such as Alzheimer’s and other neurodegenerative diseases, cancer, diabetes and infection with bacteria, fungi or viruses. There have, however, been no clinical trials to confirm the efficacy of Rn in the treatment of any of these disorders, and the safety of these teas over long periods of consumption has never been tested. This review assesses the recent research into the role of Rn and its constituent compounds in a range of diseases.

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Bronshteyn, Aleksandr M., L. V. Fedyanina, N. A. Malyshev, V. Ya Lashin, S. V. Burova, I. V. Davydova, M. S. Maksimova, and L. V. Sokolova. "ACUTE AND CHRONIC STRONGYLOIDIASIS IN RUSSIAN TOURISTS TRAVELLED TO THAILAND, THE COAST OF BLACK SEA IN RUSSIA AND ABKHAZIA: PROBLEMS OF DIAGNOSIS AND TREATMENT. ANALYSIS OF CASES AND REVIEW." Epidemiology and Infectious Diseases 22, no. 3 (June 15, 2017): 156–61. http://dx.doi.org/10.17816/eid40989.

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Cases of acute and chronic Strongyloides stercoralis are presented as tourists travelled to Thailand, the coast of Black sea in Russia and Abkhazia. A high level of clinical suspicion is required to make the diagnosis of strongyloidiasis in at-risk patients presenting with peripheral eosinophilia, unexplained intermittent diarrhea, abdominal discomfort and skin rashes. Owing to increased risk of developing disseminated disease or hyperinfection syndrome, early detection and treatment of strongyloidiasis are extremely important. Strongyloidiasis should be routinely investigated in patients with chronic diseases who will undergo immunosuppressive therapy. Ivermectin or thiabendazole currently is the treatment of choice which are more effective than albendazole.

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Chanyachailert, Pattriya, Penvadee Pattanaprichakul, Sumanas Bunyaratavej, Charussri Leeyaphan, Bawonpak Pongkittilar, Chudapa Sereeaphinan, and David Stockman. "Evaluation of Clinical Knowledge Regarding Geriatric Skin Conditions among Thai Physicians." Siriraj Medical Journal 75, no. 1 (January 1, 2023): 1–6. http://dx.doi.org/10.33192/smj.v75i1.260522.

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Objective: Assess the knowledge of common geriatric skin conditions in Thai physicians.Materials and Methods: This retrospective study was conducted among Thai physicians attending annual dermatology courses by the Dermatological Society of Thailand from 2016 to 2019. Data was assessed based on knowledge of diagnosis and management of common geriatric skin conditions.Results: A total of 197 participants, mainly general practitioners, were included. The highest percentage of correct diagnoses were benign erythematous, eczematous lesions (35.5%, senile purpura; 36.0%, xerotic eczema), and malignant diseases (35.5%, basal cell carcinoma; 27.4%, squamous cell carcinoma; 11.7%, subungual melanoma; 24.4%, acral lentiginous melanoma). In contrasts, the lowest percentage of correct diagnosis were premalignant diseases (0.5%, arsenical keratosis; 4.6%, actinic keratosis; 1.0% Bowen’s disease) and benign hypopigmented lesion (0.5%, stellate pseudoscar; 7.6%, idiopathic guttate hypomelanosis). Harmful treatment with systemic antifungal therapy was used in subungual melanoma (58.0%). Harmful management of senile comedone, subungual melanoma and acral lentiginous melanoma was significantly found in physicians given the incorrect diagnosis. (p = 0.027, p <0.001, p = 0.014, respectively).Conclusion: Most physicians recognized malignant lesions, benign erythematous or eczematous diseases in elderly skin. Surprisingly, almost all physicians couldn’t diagnose premalignant lesions and benign hypopigmented lesions.

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Velmani S, Perumal B, Santhosh C, and Maruthupandian A. "Phytochemical and Traditional uses on Acanthus ilicifolius (L)." JOURNAL OF ADVANCED APPLIED SCIENTIFIC RESEARCH 1, no. 3 (December 15, 2021): 43–48. http://dx.doi.org/10.46947/joaasr13201617.

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Acanthus ilicifolius is a spiny herb found in mangrove of southern Thailand. It is also widely distributed in India and other tropical regions of Asia. The plant is reported to contain phytochemicals including alkaloid and wide range of glucosides (lignan and phenylethanoid). In traditional medicine, the plant is used in the treatment of diseases ranging from snake bite to skin diseases. A. ilicifolius (sea holly) occurs in tropical Asia and Africa, through Malaya to Polynesia. It is a vine shrub or tall herb, up to 1.5 m high, scarcely woody, bushy, with very dense growth. Common names of which are holy leaved acanthus, sea holly and holy mangrove. A. ilicifoliusis abundantly available in freshwater ecosystem of Pichavaram mangroves located in southeast coast of India. The review analyses traditional medicinal usage, and phytochemical investigations done on the A. ilicifoliusis medicinal plant.

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Assanangkornchai, Sawitri, Darika Saingam, Kanittha Thaikla, and Muhammadfahmee Talek. "Views and practices on medical cannabis of unlicensed providers in Thailand: a qualitative study." F1000Research 11 (March 29, 2022): 365. http://dx.doi.org/10.12688/f1000research.110367.1.

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Background: Despite the legalization of cannabis use for medical purposes in Thailand in February 2019, illicit providers are still widespread and accessible. This study aimed to understand why people still chose to receive medical cannabis treatment or products from unlicensed or illegal providers. The practices of unlicensed or illegal providers in provision of medical cannabis products or treatment services were also examined. Methods: Qualitative in-depth interviews were conducted among medical cannabis providers and users, including 36 unlicensed and 7 licensed providers and 25 users in 2019-2021. Snowball sampling was used to recruit participants until saturation of data was achieved. Interviews included open-ended questions about the providers’ practices and attitudes towards medical cannabis. Interviews were recorded and transcribed, and thematic analysis was performed. Results: Overall, six reasons were identified to answer why unlicensed/illicit providers were still popular, including: 1) easy accessibility; 2) familiarity with the unlicensed providers before the legal scheme became available; 3) favorable characters (kind, supportive, non-judgmental) of unlicensed providers; 4) affordable treatment fees; 5) trust in the quality of the medicines; and 6) lack of knowledge and negative attitudes towards cannabis from healthcare professionals. Most providers started their career as medical cannabis providers by using it themselves or with their relatives and being satisfied with the results. They used cannabis products to treat all diseases, including skin, eyes, HIV/AIDS, non-communicable diseases and all kinds of cancers. Additionally, they believed that it was effective, with no or minimal adverse effects. Conclusions: This study suggests that some patients will continue receiving medical cannabis treatment and products from unlicensed or illegal providers. More attention should be paid on increasing the capacity of medical cannabis service systems within public health hospitals, and the certification of unlicensed providers, so as to integrate them into a regulated system.

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Sangboonruang, Sirikwan, Kuntida Kitidee, Panuwan Chantawannakul, Khajornsak Tragoolpua, and Yingmanee Tragoolpua. "Melittin from Apis florea Venom as a Promising Therapeutic Agent for Skin Cancer Treatment." Antibiotics 9, no. 8 (August 14, 2020): 517. http://dx.doi.org/10.3390/antibiotics9080517.

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Melittin, a major component found in bee venom, is produced by the Apis species of the honey bee. In this study, the effect of melittin derived from Apis florea (Mel-AF), which is a wild honey bee species that is indigenous to Thailand, was investigated against human malignant melanoma (A375) cells. In this study, Mel-AF exhibited considerable potential in the anti-proliferative action of A375 cells. Subsequently, the cellular mechanism of Mel-AF that induced cell death was investigated in terms of apoptosis. As a result, gene and protein expression levels, which indicated the activation of cytochrome-c release and caspase-9 expression, eventually triggered the release of the caspase-3 executioner upon Mel-AF. We then determined that apoptosis-mediated cell death was carried out through the intrinsic mitochondrial pathway. Moreover, advanced abilities, including cell motility and invasion, were significantly suppressed. Mel-AF manipulated the actin arrangement via the trapping of stress fibers that were found underneath the membrane, which resulted in the defective actin cytoskeleton organization. Consequently, the expression of EGFR, a binding protein to F-actin, was also found to be suppressed. This outcome strongly supports the effects of Mel-AF in the inhibition of progressive malignant activity through the disruption of actin cytoskeleton-EGFR interaction and the EGFR signaling system. Thus, the findings of our current study indicate the potential usefulness of Mel-AF in cancer treatments as an apoptosis inducer and a potential actin-targeting agent.

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Jarernsook, B., S. Siritho, and N. Prayoonwiwat. "Efficacy and safety of beta-interferon in Thai patients with demyelinating diseases." Multiple Sclerosis Journal 19, no. 5 (September 11, 2012): 585–92. http://dx.doi.org/10.1177/1352458512459290.

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Background: The efficacy of beta-interferon (IFN-β) treatment in Thai patients with demyelinating diseases has not been reported. Objectives: To evaluate the efficacy and any adverse drug reactions of IFN-β therapy in Thai patients, for each group of demyelinating diseases. Methods: We retrospectively reviewed data of Thai patients with multiple sclerosis (MS), neuromyelitis optica (NMO) and NMO spectrum disorders (NMOSDs) who attended the MS Clinic at Siriraj Hospital, Thailand from March 2000 to October 2011. We reviewed those 73 patients who received IFN-β. We evaluated the drug’s efficacy over 2 years and any adverse drug reactions among these patients. Results: Of the 40 MS patients who received IFN-β, 26 adhered to the medication for at least 2 years. In addition, 27 NMO/NMOSDs patients who had been diagnosed with MS were treated as such with IFN-β. In the true MS group, the pre- and post-treatment annualized relapse rates (ARR) were 1.25 and 0.59, respectively, so there was a reduction of 52.8% ( p = 0.004). In addition, in 69.2% of the patients, IFN-β also showed beneficial effects by prolonging the time to first relapse to 15.9 months and stabilizing or decreasing progression of the disease. In contrast, no significant benefit was seen in the NMO/NMOSDs group. On the contrary, an increase in EDSS was seen in 53.3 % of them. The most common side effects seen were local skin reactions and flu-like symptoms. Conclusions: Treatment with IFN-β was effective in reducing both ARR and disability progression in Thai patients with MS. In contrast, we observed that giving IFN-β treatment to NMO/NMOSDs patients may lead to a worsening of symptoms.

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Chaudhari, Latesh Y., Saurabh P. Chaudhari, and Ghanshyam M. Chavan. "A BRIEF REVIEW ON TULSI: A HOLY PLANT WITH HIGH MEDICINAL VALUES AND THERAPEUTIC USES." International Journal of Research in Ayurveda and Pharmacy 13, no. 3 (June 7, 2022): 118–25. http://dx.doi.org/10.7897/2277-4343.130372.

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This is a medicinal plant belonging to the family Lamiaceae, and the botanical name is Ocimum Sanctum. Tulsi is widely used for its various healing properties and is called a ‘queen of the herb’. All the parts of the plant are helpful, including leaves and seeds. The Incomparable One and the mother of natural medicine are the other names of Tulsi. Tulsi is available in India, Burma, Sri Lanka, Bangladesh, Southwest Asia, China, Thailand, and Malaysia. The plant is an erect, much-branched subshrub, 30-60cm tall, with hairy stems and simple, green leaves that are strongly scented. It is native globally tropics and widely cultivated for its medicinal value. In the traditional system of medicine, different parts of Tulsi have been recommended for the treatment of bronchitis, malaria, diarrhoea, dysentery, skin diseases, eye diseases, arthritis, insect bites, and so on. Pharmacological actions like anti-cancer, antidiabetic, antioxidant, antimalarial, antimicrobial, and anti-fertility are present in the Aromatic plant. These activities may be attributed mainly to phytochemicals like eugenol, ursolic acid, rosmarinic acid, methyl chavicol, linalool, etc.

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Hackel, Meredith, Gregory Stone, and Daniel F. Sahm. "1245. In Vitro Activities of Ceftaroline and Comparator Agents Against Bacterial Pathogens Collected from Patients with Skin and Skin Structure Infections: ATLAS Global Surveillance Program 2012-2019." Open Forum Infectious Diseases 8, Supplement_1 (November 1, 2021): S711. http://dx.doi.org/10.1093/ofid/ofab466.1437.

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Abstract Background Ceftaroline fosamil, the prodrug of ceftaroline, is a parenteral cephem approved for the treatment of patients with skin and skin structure infections (SSSIs) caused by Staphylococcus aureus (both methicillin-susceptible [MSSA] and methicillin-resistant [MRSA] isolates), β-hemolytic streptococci (Streptococcus pyogenes, S. agalactiae, S. dysgalactiae), and select species of Enterobacterales (Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca). The current study is part of the ATLAS (Antimicrobial Testing Leadership and Surveillance) program and evaluated the current activities of ceftaroline and comparator agents against commonly encountered bacterial isolates associated with SSSIs. Methods From 2012 to 2019 the ATLAS program received 124,694 bacterial isolates that had been cultured by 493 clinical laboratories in 71 countries from samples of patients diagnosed with SSSIs. All isolates were transported to IHMA, (Schaumburg, IL, USA) where their identities were confirmed using MALDI-TOF mass spectrometry and antimicrobial susceptibility testing performed following standardized CLSI broth microdilution methodology (M07). Percent susceptibilities were determined using 2021 CLSI MIC breakpoints. Phenotypic extended-spectrum β-lactamase (ESBL) screening and confirmatory testing were performed using the CLSI M100 method. Results The in vitro activity of ceftaroline is summarized in the following table. Overall, >99.9% of MSSA and 92.8% of MRSA from SSSI were susceptible to ceftaroline (MIC ≤1 µg/ml); 7.1% of MRSA isolates were ceftaroline-susceptible dose-dependent (MIC 2-4 µg/ml) with greatest proportion being from Chile (53.3% of 392 isolates), S. Korea (29.3% of 321 isolates), and China (24.7% of 652 isolates). Twelve ceftaroline-resistant MRSA were observed, consisting of 11 of 109 isolates from Thailand (10.1%) and 1 of 161 from China (0.6%). All S. pyogenes and 88.0% of ESBL-negative Enterobacterales were susceptible to ceftaroline. Results Table Conclusion Ceftaroline continues to demonstrate potent in vitro activity against clinically relevant pathogens associated with SSSIs. Disclosures Meredith Hackel, PhD MPH, IHMA (Employee)Pfizer, Inc. (Independent Contractor) Gregory Stone, PhD, AztraZeneca (Shareholder, Former Employee)Pfizer, Inc. (Employee) Daniel F. Sahm, PhD, IHMA (Employee)Pfizer, Inc. (Independent Contractor)

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Iizuka, Toru, Rina Ogata, Jing Yu, and Yasuo Watanabe. "Vasorelaxant Effects of Coriandrum SativumL. Extract on Rat Isolated Aorta." Journal of Nutritional Health & Food Science 9, no. 1 (November 19, 2020): 1–8. http://dx.doi.org/10.15226/jnhfs.2020.001179.

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Aim: Coriander(Coriandrum sativum L.) is an annual plant belonging to the family Umbelliferae, which distributed in Central and Western Europe, India, Bangladesh, Thailand, China, and other Asian regions. Besides being edible, coriander is an important traditional medicine in India and China, and is used to treat circulatory disorders, such as respiratory, urinary tract, and skin diseases. In this study, we investigated the vasorelaxant effects of extracts from coriander and further studied to clarify their action mechanisms. Method: The aerial part of coriander, which analyzed the rutin content as its quality evaluand using a chromatographic method (HPLC), was cut and extracted with ethyl acetate or hot water. The extracts were concentrated under the reduced pressure. Vasorelaxant effects of these extracts were assessed on rat isolated aorta. The aorta was placed in a well-oxygenated bath of modified Krebs-Henseleit solution and the mechanical tension was measured isometrically. Results: These extracts showed vasorelaxant effects on aorta precontracted with 3×10-7 M norepinephrine (NE). The ethyl acetate extract showed biphasic vasorelaxation (fast and slowly developing relaxations) on isolated rat aortic rings with endothelium. Fast relaxation disappeared in deendothelialized or pre-administration of 10-4 M L-NG-monomethylarginine. Furthermore, the hot water extract showed only slowly developing relaxations independent in endothelium. After treatment with the hot water extract, NE-induced phasic vasoconstriction was not inhibited. While the hot water extract inhibited vasoconstrictions induced by a high concentration (60 mM) of K+ and also showed inhibitory effect on NE-induced vasoconstriction in the presence of nicardipine. Conclusion: These results suggest that the vasorelaxant effect of ethyl acetate extract of coriander on NE-induced vasoconstriction may be attributed to Nitric Oxide (NO) releasing dependent on endothelium. And the hot water extract of coriander showed vasorelaxant activities attributed to blocking of Ca2+ influx via voltage-depended Ca2+ channels (VDCs) and receptor-operated Ca2+ channels (ROCs), but not competing for the adrenergic receptor. Keywords: Coriandrum sativum; quality evaluation; vasorelaxant effects; aorta; endothelium; Ca2+ channel

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Ilieva, Vasilka. "MORINGA OLEIFERA - FOOD AND MEDICINE FOR THE MODERN WORLD - MINI REVIEW." Knowledge International Journal 34, no. 4 (October 4, 2019): 1081–87. http://dx.doi.org/10.35120/kij34041081i.

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The Challenges of Modernity - Stress, Obesity, Socially Significant Diseases require the search for opportunities for prevention and treatment through sources of nature. In the food chain of modern man there is a total shortage of "living photons" from the sun, nutrients supplied by primordial sources residing in the natural environment, giving the cell both nutritional and energy resources and information from the living environment of the plant world. Overweight, metabolic syndrome and the resulting complications such as hypertension, atherosclerosis and diabetes have been proven to be linked to the modern diet. It is a source of substances that support inflammatory processes in the body. Hippocrates has also said that food is our medicine. The Moringa oleifera plant has features that attract the attention of science from different fields. Moringa oleifera is grown in tropical and subtropical regions at an altitude of 0 to 2000 meters. The plant prefers well-drained clay and sandy soils. The birthplace of Moringa oleifera is the southern foothills of the Himalayas. The plant is widely cultivated in India. The leaders in the Moringa industry are Andhra Pradesh, Karnataka and Tamil Nadu. It is also cultivated in Africa, Thailand, the Philippines, Indonesia, Haiti and Taiwan, Southeast Asia, some US states, including Hawaii and various countries in Oceania, as well as in Peru, Paraguay, the Pacific, the Caribbean and South America. Traditionally, in these areas, the plant is used as food and medicine. In many poor regions, Moringa oleifera is a food source of proteins, vitamins and minerals. Moringa oleifera is used in traditional medicine in many societies as a medicine. The Ayurvedic healing system uses the plant to treat 300 diseases. In addition to food and medicine, Moringa oleifera is used to purify water in areas without drinking water sources, to produce oil that is used as a lubricant, as well as in paint. In ancient Egypt, it was prized for its moisturizing properties and later used by the Romans. It is known as a cosmetic for skin rejuvenation and production of perfumes and soaps. Moringa oleifera can be considered an important functional food - a source of substances important to the human body. The unusual properties and wide application of the plant in various fields of human life are of high scientific interest. The ability of Moringa oleifera to influence many of the present-day disease states has been proven. Almost all parts from Moringa can be used as a source for nutrition with other useful values.It has antioxidant properties, which are the basis of anti-inflammatory, anti-cancer effects, anti-dyslipidemic effect, effects of type 2 diabetes, anti-asthmatic, antibacterial, neuroprotective effect.

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Thamlikitkul, Visanu, Somporn Santiprasitkul, Luckna Suntanondra, Sumalee Pakaworawuth, Surapee Tiangrim, Suthipol Udompunthurak, and Somwang Danchaivijitr. "Skin flora of patients in Thailand." American Journal of Infection Control 31, no. 2 (April 2003): 80–84. http://dx.doi.org/10.1067/mic.2003.64.

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Beckenbach, Lisa, Jens M. Baron, Hans F. Merk, Harald Löffler, and Philipp M. Amann. "Retinoid treatment of skin diseases." European Journal of Dermatology 25, no. 5 (September 2015): 384–91. http://dx.doi.org/10.1684/ejd.2015.2544.

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Phraisuwan, Phran, Ellen A. Spotts Whitney, Piyanit Tharmaphornpilas, Suriya Guharat, Samart Thongkamsamut, Suphaporn Aresagig, Jayteeya Liangphongphanthu, Kanlayanee Junthima, Apirat Sokampang, and David A. Ashford. "Leptospirosis: Skin Wounds and Control Strategies, Thailand, 1999." Emerging Infectious Diseases 8, no. 12 (December 2002): 1455–59. http://dx.doi.org/10.3201/eid0812.020180.

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Fivenson, David P. "NONSTEROIDAL TREATMENT OF AUTOIMMUNE SKIN DISEASES." Dermatologic Clinics 15, no. 4 (October 1997): 695–705. http://dx.doi.org/10.1016/s0733-8635(05)70479-4.

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Thongphunchung, Khanut, Panita Charoensuk, Sutida U-tapan, Wassana Loonsamrong, Arthit Phosri, and Wiriya Mahikul. "Outpatient Department Visits and Mortality with Various Causes Attributable to Ambient Air Pollution in the Eastern Economic Corridor of Thailand." International Journal of Environmental Research and Public Health 19, no. 13 (June 23, 2022): 7683. http://dx.doi.org/10.3390/ijerph19137683.

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The Eastern Economic Corridor in Thailand is undergoing development, but industrial activities are causing serious air pollution. This study aimed to examine the effects of particulate matter (PM10), fine particulate matter (PM2.5), SO2, NO2, O3, and CO on outpatient department (OPD) visits and mortality with various causes in the Eastern Economic Corridor, Thailand between 2013 and 2019 using a case-crossover design and conditional Poisson model. The corresponding burden of disease due to air pollution exposure was calculated. A 1 µg/m3 increase in the PM10 was associated with significant increases in OPD visits for circulatory diseases (0.22, 95% CI 0.01, 0.34), respiratory diseases (0.21, 95% CI 0.13, 0.28), and skin and subcutaneous tissue diseases (0.18, 95% CI 0.10, 0.26). By contrast, a 1 µg/m3 increase in the PM10 was associated with significant increases in mortality from skin and subcutaneous tissue diseases (0.79, 95% CI 0.04, 1.56). A 1 µg/m3 increase in PM2.5 was associated with significant increases in mortality from circulatory diseases (0.75, 95% CI 0.20, 1.34), respiratory diseases (0.82, 95% CI 0.02, 1.63), and skin and subcutaneous tissue diseases (2.91, 95% CI 0.99, 4.86). The highest OPD burden was for circulatory diseases. Respiratory effects were attributed to PM10 exceeding the national ambient air quality standards (NAAQS) of Thailand (120 μg/m3). The highest morbidity burden was for skin and subcutaneous tissue diseases attributed to PM2.5 concentrations that exceeded the NAAQs (50 μg/m3). PM pollution in the EEC could strongly contribute to OPD visits and morbidity from various diseases. Preventing PM10 concentrations from being higher than 60 µg/m3 could decrease OPD visits by more than 33,265 and 29,813 for circulatory and respiratory diseases, respectively. Our study suggests that such pollution increases the risks of OPD visits and mortality in various causes in the Thai EEC. Reducing the ambient air pollution concentration of NAAQSs in Thailand could reduce the health effect on the Thai population.

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Chaiyamahapurk, Sakchai, and Prateep Warnnissorn. "Prevalence and Pattern of Diseases of The Skin and Subcutaneous Tissue in A Primary Care Area in Thailand." Siriraj Medical Journal 73, no. 6 (May 27, 2021): 357–62. http://dx.doi.org/10.33192/smj.2021.47.

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Objective: Information on the population-based prevalence study of skin diseases is still lacking. The study explores the prevalence and pattern of diagnosed skin diseases of the population in a primary care area of a university hospital in Thailand.Materials and Methods: Skin disease patients were identified using the International Statistical Classification of Diseases and Related Health Problems 10th Revision codes (L00-L99). Retrospective data were obtained from the hospital electronic medical record between 2015-2019. The number of clinic visits and the number of skin disease diagnoses were counted. The five-year period prevalence was calculated by dividing the number of cases by the population in the primary care area.Results: During the five-year period, in a population of 29,969, we found 3,770 patients (12.6% of 29,969 population) who made 7,433 outpatient visits with the diagnoses of skin diseases. Infections of the skin and subcutaneous tissues were the most common (37.3%), followed by dermatitis (29.7%), urticaria and erythema (13.9%), other disorders of the skin and subcutaneous tissue (8.6%), and papulosquamous disorders (1.7%). The five-year period prevalence of skin diseases per 100,000 persons was as following: cellulitis (2,296), urticaria (1,682), psoriasis (177), atopic dermatitis (420), seborrheic dermatitis (227), alopecia areata (50), vitiligo (23), and pemphigus (10).Conclusion: Infection and dermatitis were the two most common skin diseases in the primary care area population. Atopic dermatitis, psoriasis, seborrheic dermatitis, and decubitus ulcer were less commonly found. Our prevalence data should be the “at least” prevalence of skin diseases due to possible underreporting.

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Hiransuthikul, N., W. Tantisiriwat, K. Lertutsahakul, A. Vibhagool, and P. Boonma. "Skin and Soft-Tissue Infections among Tsunami Survivors in Southern Thailand." Clinical Infectious Diseases 41, no. 10 (November 15, 2005): e93-e96. http://dx.doi.org/10.1086/497372.

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Koller, Ulrich, and Johann W. Bauer. "Molecular Research and Treatment of Skin Diseases." International Journal of Molecular Sciences 23, no. 10 (May 13, 2022): 5435. http://dx.doi.org/10.3390/ijms23105435.

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The intention of this Special Issue is to highlight current treatment options to target the cause, as well as disease-associated complications, of skin diseases, including a group of monogenetic skin disorders referred to as genodermatoses [...]

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Vasani, Resham, and Murlidhar Rajagopalan. "Rituximab in the treatment of skin diseases." Indian Journal of Drugs in Dermatology 3, no. 2 (2017): 105. http://dx.doi.org/10.4103/ijdd.ijdd_31_17.

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22

G., V. "Treatment of skin diseases with calcium salts." Kazan medical journal 20, no. 6 (August 11, 2021): 648. http://dx.doi.org/10.17816/kazmj76817.

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Rosentul (Med. Ob. Iizhn. Pov., 1924, No. 5) saw very good results from the use of calcium salts, in the form of intravenous injections of a 10% solution of calcium chloride, 10 cubic meters each. with. PA injection, with the latter being repeated daily, for a number of skin diseases, namely, for acute eczema, urticaria, herpes zoster, lichen chronicus Vidaln, pruritus vulvae, pruritus ani, dermatitis herpetiformis Dhringa, etc.

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23

Bork, Konrad, W. Brauninger, H. K. Mueller, and Thomas B. Fitipatrick. "Diagnosis and Treatment of Common Skin Diseases." Plastic and Reconstructive Surgery 86, no. 3 (September 1990): 595. http://dx.doi.org/10.1097/00006534-199009000-00040.

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24

Fitzpatrick, Thomas B. "Diagnosis and Treatment of Common Skin Diseases." Archives of Dermatology 125, no. 7 (July 1, 1989): 1021. http://dx.doi.org/10.1001/archderm.1989.01670190155029.

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25

Brieva, Joaquin C. "Treatment of Skin Diseases: Comprehensive Therapeutic Strategies." Archives of Dermatology 139, no. 9 (September 1, 2003): 1226. http://dx.doi.org/10.1001/archderm.139.9.1226-b.

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26

Hassan, Tahmida, Masuda Mohsena, Abida Sultana, Lubna Khondoker, Shiropa Islam, and Razia Sultana. "Pregnancy related skin changes and skin diseases." Bangladesh Medical Journal 44, no. 2 (April 5, 2016): 112–16. http://dx.doi.org/10.3329/bmj.v44i2.27256.

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The skin and related structures undergo changes during pregnancy and peurperium. They can be separated into three categories - hormone related pregnancy specific and preexisting. the physiologic changes are mainly of cosmetic importance. The pregnancy specific skin diseases have associated symptoms. Most skin conditions resolve post partum and only require symptomatic treatment. Some of them are associated with an increase in both fetal and/or maternal morbidity and mortality.Bangladesh Med J. 2015 May; 44 (2): 112-116

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27

NAKAYAMA, HIDEO. "Treatment of xerotic skin diseases with Minon cream." Nishi Nihon Hifuka 47, no. 3 (1985): 538–45. http://dx.doi.org/10.2336/nishinihonhifu.47.538.

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28

Hirobe, Sachiko, and Naoki Okada. "Treatment of skin diseases applying the microneedle technology." Drug Delivery System 33, no. 4 (September 25, 2018): 293–302. http://dx.doi.org/10.2745/dds.33.293.

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29

Ihn, Hironobu. "Treatment of skin ulcers in collagen vascular diseases." Japanese journal of leprosy 77, no. 3 (2008): 211–13. http://dx.doi.org/10.5025/hansen.77.211.

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30

Rosted, P. "Treatment of skin diseases with acupuncture a review." Journal of Dermatological Treatment 6, no. 4 (January 1995): 241–42. http://dx.doi.org/10.3109/09546639509086853.

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31

Luger, T. A. "Cytokine treatment of mast-cell-mediated skin diseases." Experimental Dermatology 4, no. 4 (August 1995): 277–80. http://dx.doi.org/10.1111/j.1600-0625.1995.tb00258.x.

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32

Yohn, Joseph. "Diagnosis and Treatment of Common Skin Diseases (Book)." Journal of Investigative Dermatology 94, no. 1 (January 1990): 156. http://dx.doi.org/10.1111/1523-1747.ep12874062.

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Buchness, Mary Ruth. "Treatment of Skin Diseases in HIV-Infected Patients." Dermatologic Clinics 13, no. 1 (January 1995): 231–38. http://dx.doi.org/10.1016/s0733-8635(18)30122-0.

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34

Stern, Robert S. "Managed Care and the Treatment of Skin Diseases." Archives of Dermatology 132, no. 9 (September 1, 1996): 1039. http://dx.doi.org/10.1001/archderm.1996.03890330053009.

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35

BASS, JAMES W. "Treatment of skin and skin structure infections." Pediatric Infectious Disease Journal 11, no. 2 (February 1992): 152–55. http://dx.doi.org/10.1097/00006454-199202000-00032.

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36

Thongtaeparak, Wittaya, Walai-orn Pratchyapruit, Settha Kotanivong, Nimit Sirithanakit, Sudaluck Thunyaharn, Ram Rangsin, Phachara Chaikaew, et al. "Prevalence of and Risk Factors for Skin Diseases Among Army Personnel and Flood Victims During the 2011 Floods in Thailand." Disaster Medicine and Public Health Preparedness 10, no. 4 (February 17, 2016): 570–75. http://dx.doi.org/10.1017/dmp.2015.182.

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AbstractObjectiveThis study aimed to determine the prevalence of and risk factors for skin problems among flood victims and army personnel during the 2011 floods in Thailand.MethodsTo determine the prevalence of and risk factors for skin symptoms, standardized questionnaires were used to collect demographic data, current skin symptoms, history of water exposure, and sanitary behaviors. A certified dermatologist evaluated those who presented with skin problems and provided diagnoses. Univariate and multivariate analyses were performed to assess independent risk factors for skin symptoms.ResultsThe most prevalent skin disease was irritant contact dermatitis. Flood victims showed a higher prevalence of skin symptoms compared with army personnel. Development of skin symptoms after exposure to floodwater was also observed earlier among flood victims. Having a history of skin diseases and delayed skin cleaning after exposure were also significant risk factors for the development of skin symptoms.ConclusionThis information might be used as guidelines for protecting military personnel and to educate the general public regarding flood disaster management. (Disaster Med Public Health Preparedness. 2016;10:570–575)

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Russo, Alessandro, Antonio Vena, and Matteo Bassetti. "Antibiotic treatment of acute bacterial skin and skin structure infections." Current Opinion in Infectious Diseases 35, no. 2 (April 2022): 120–27. http://dx.doi.org/10.1097/qco.0000000000000822.

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Golan, Yoav. "Current Treatment Options for Acute Skin and Skin-structure Infections." Clinical Infectious Diseases 68, Supplement_3 (April 1, 2019): S206—S212. http://dx.doi.org/10.1093/cid/ciz004.

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39

Over, Mead, Ana Revenga, Emiko Masaki, Wiwat Peerapatanapokin, Julian Gold, Viroj Tangcharoensathien, and Sombat Thanprasertsuk. "The economics of effective AIDS treatment in Thailand." AIDS 21, Suppl 4 (July 2007): S105—S116. http://dx.doi.org/10.1097/01.aids.0000279713.39675.1c.

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Sidorovich, O. I., and E. A. Tsyvkina. "Photodermatoses: prevention and treatment." Medical Council, no. 12 (July 29, 2018): 132–34. http://dx.doi.org/10.21518/2079-701x-2018-12-132-134.

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Increased exposure of the skin to sunlight has many negative effects: premature skin aging (photoaging), the risk of various skin cancers, the appearance of hyperpigmentation, and exacerbation of certain skin diseases.

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Hartmann, M., and A. Enk. "Mycophenolate mofetil and skin diseases." Lupus 14, no. 3_suppl (March 2005): 58–63. http://dx.doi.org/10.1191/0961203305lu2121oa.

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Mycophenolate mofetil (MMF) is an immunosuppressive drug the efficiency of which has been established in renal transplantation. Recent studies suggest that it may also be effective in the treatment of variant skin diseases especially if the skin lesions are triggered by lymphocytes. Studies have shown efficacy in autoimmune bullous dermatoses, atopic dermatitis and psoriasis. However, there are no placebo-controlled trials that support the use of MMF as first line therapy in these skin diseases.

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Matoshvili, Maia, and Davit Tophuria. "HERBS USED TO TREAT SKIN DISEASES." Ambiance in Life International Scientific Journal in Medicine of Southern Caucasus 05, no. 03 (November 10, 2020): 04–05. http://dx.doi.org/10.36962/0503202004.

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Skin diseases are numerous and a frequently occurring health problem affecting all ages from the neonates to the elderly and cause harm in number of ways. Maintaining healthy skin is important for a healthy body. Many people may develop skin diseases that affect the skin, including cancer, herpes and cellulitis. Some wild plants and their parts are frequently used to treat these diseases. The use of plants is as old as the mankind. Natural treatment is cheap and claimed to be safe. It is also suitable raw material for production of new synthetic agents. A review of some plants for the treatment of skin diseases is provided that summarizes the recent studies. Natural drugs from the plants are gaining popularity because of several advantages such as often having fewer side-effects, better patient tolerance, being relatively less expensive and acceptable due to a long history of use. Besides herbal medicines provide rational means for the treatment of many diseases that are obstinate and incurable in other systems of medicine. For these reasons several plants have been investigated for treatment of skin diseases ranging from itching to skin cancer. So far 31 plants have been reported to be effective in various skin diseases during the past 17 years (1995-2012) of research work, which are mentioned below.

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43

Maranetra, Khun Nanta. "Treatment of Multidrug-Resistant Tuberculosis in Thailand." Chemotherapy 42, no. 3 (1996): 10–15. http://dx.doi.org/10.1159/000239508.

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Mande, P., S. Borthakur, D. Rios, P. Halvey, A. Boisvert, M. Rowe, M. Cianci, et al. "LB783 Skin-tethered bifunctional antibodies for treatment of autoimmune and inflammatory skin diseases." Journal of Investigative Dermatology 141, no. 9 (September 2021): B18. http://dx.doi.org/10.1016/j.jid.2021.07.047.

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45

Souto, Eliana B., Ana L. R. de Souza, Fernanda K. dos Santos, Elena Sanchez-Lopez, Amanda Cano, Aleksandra Zielińska, Rafał Staszewski, Jacek Karczewski, Maria P. D. Gremião, and Marlus Chorilli. "Lipid Nanocarriers for Hyperproliferative Skin Diseases." Cancers 13, no. 22 (November 10, 2021): 5619. http://dx.doi.org/10.3390/cancers13225619.

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Hyperproliferative skin diseases (HSD) are a group of diseases that include cancers, pre-cancerous lesions and diseases of unknown etiology that present different skin manifestations in terms of the degree and distribution of the injuries. Anti-proliferative agents used to treat these diseases are so diverse, including 5-aminolevulinic acid, 5-fluorouracil, imiquimod, methotrexate, paclitaxel, podophyllotoxin, realgar, and corticosteroids in general. These drugs usually have low aqueous solubility, which consequently decreases skin permeation. Thus, their incorporation in lipid nanocarriers has been proposed with the main objective to increase the effectiveness of topical treatment and reduce side effects. This manuscript aims to describe the advantages of using lipid nanoparticles and liposomes that can be used to load diversity of chemically different drugs for the treatment of HSD.

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Mahaisavariya,, Punkae, Angkana Chaiprasert,, DR reR naT ,. Apichati Sivayathorn,, and Supakan Khemngern,. "Deep fungal and higher bacterial skin infections in Thailand: clinical manifestations and treatment regimens." International Journal of Dermatology 38, no. 4 (April 1999): 279–84. http://dx.doi.org/10.1046/j.1365-4362.1999.00681.x.

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Kui, Róbert, Ekaterine Paschali, Réka Kovács, Magdolna Gaál, Eszter Baltás, and Lajos Kemény. "Novel treatment options in immune-mediated inflammatory skin diseases." Bőrgyógyászati és Venerológiai Szemle 95, no. 2 (May 10, 2019): 60–64. http://dx.doi.org/10.7188/bvsz.2019.95.2.5.

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48

Dawid-Pać, Renata. "Medicinal plants used in treatment of inflammatory skin diseases." Advances in Dermatology and Allergology 3 (2013): 170–77. http://dx.doi.org/10.5114/pdia.2013.35620.

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Hasegawa, Toshio, and Shigaku Ikeda. "Mesenchymal Stem Cells for the Treatment of Skin Diseases." AIMS Cell and Tissue Engineering 1, no. 2 (2017): 104–17. http://dx.doi.org/10.3934/celltissue.2017.2.104.

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50

Elisyutina, O. G. "Fluticasone propionate in the topical treatment of skin diseases." Russian Journal of Allergy 7, no. 5 (December 15, 2009): 106–12. http://dx.doi.org/10.36691/rja947.

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