Journal articles on the topic 'Single cell metabolic flux'
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Wagner, Allon, Chao Wang, David DeTomaso, Arman Koul, Aviv Regev, Vijay K. Kuchroo, and Nir Yosef. "Cell-specific metabolic models reveal novel metabolic regulators of Th17 pathogenicity: from single-cell RNA-Seq to actionable metabolic targets." Journal of Immunology 200, no. 1_Supplement (May 1, 2018): 163.21. http://dx.doi.org/10.4049/jimmunol.200.supp.163.21.
Full textLand, S. C., D. M. Porterfield, R. H. Sanger, and P. J. Smith. "The self-referencing oxygen-selective microelectrode: detection of transmembrane oxygen flux from single cells." Journal of Experimental Biology 202, no. 2 (January 15, 1999): 211–18. http://dx.doi.org/10.1242/jeb.202.2.211.
Full textLee, Geonhui, Thomas Ruan, Claudia Wong, Kofi Deh, Alli Abolarin, Alexander Correa, Kayvan R. Keshari, and Sangmoo Jeong. "Micro-Slab Coil Design for Hyperpolarized Metabolic Flux Analysis in Multiple Samples." Bioengineering 10, no. 1 (December 21, 2022): 14. http://dx.doi.org/10.3390/bioengineering10010014.
Full textWagner, Allon, Chao Wang, David DeTomaso, Julian Avila Pacheco, Sarah Zaghouani, Johannes Fessler, Elliot Akama-Garren, et al. "In Silico Modeling of Metabolic State in Single Th17 Cells Reveals Novel Regulators of Inflammation and Autoimmunity." Journal of Immunology 204, no. 1_Supplement (May 1, 2020): 150.22. http://dx.doi.org/10.4049/jimmunol.204.supp.150.22.
Full textDai, David, Nicholas Horvath, and Jeffrey Varner. "Dynamic Sequence Specific Constraint-Based Modeling of Cell-Free Protein Synthesis." Processes 6, no. 8 (August 17, 2018): 132. http://dx.doi.org/10.3390/pr6080132.
Full textYasukawa, Tomoyuki, Andrew Glidle, Jonathan M. Cooper, and Tomokazu Matsue. "Electroanalysis of Metabolic Flux from Single Cells in Simple Picoliter-Volume Microsystems." Analytical Chemistry 74, no. 19 (October 2002): 5001–8. http://dx.doi.org/10.1021/ac025836u.
Full textGüell, Oriol, Francesco Alessandro Massucci, Francesc Font-Clos, Francesc Sagués, and M. Ángeles Serrano. "Mapping high-growth phenotypes in the flux space of microbial metabolism." Journal of The Royal Society Interface 12, no. 110 (September 2015): 20150543. http://dx.doi.org/10.1098/rsif.2015.0543.
Full textSengupta, Debanti, Amy Mongersun, Tae Jin Kim, Kellen Mongersun, Rie von Eyben, Paul Abbyad, and Guillem Pratx. "Multiplexed Single-Cell Measurements of FDG Uptake and Lactate Release Using Droplet Microfluidics." Technology in Cancer Research & Treatment 18 (January 1, 2019): 153303381984106. http://dx.doi.org/10.1177/1533033819841066.
Full textChung, J., R. Clifford, G. Sriram, and C. Keefer. "68 Flux analysis of aerobic glycolysis in bovine blastocysts and CT1 cells." Reproduction, Fertility and Development 31, no. 1 (2019): 159. http://dx.doi.org/10.1071/rdv31n1ab68.
Full textDe Martino, A., D. Granata, E. Marinari, C. Martelli, and V. Van Kerrebroeck. "Optimal Fluxes, Reaction Replaceability, and Response to Enzymopathies in the Human Red Blood Cell." Journal of Biomedicine and Biotechnology 2010 (2010): 1–10. http://dx.doi.org/10.1155/2010/415148.
Full textZhang, Zhichao, Qing Zhang, Shaohua Guan, and Hualin Shi. "Quantitative Connection between Cell Size and Growth Rate by Phospholipid Metabolism." Cells 9, no. 2 (February 8, 2020): 391. http://dx.doi.org/10.3390/cells9020391.
Full textSarkar, Debolina, Marine Landa, Anindita Bandyopadhyay, Himadri B. Pakrasi, Jonathan P. Zehr, and Costas D. Maranas. "Elucidation of trophic interactions in an unusual single-cell nitrogen-fixing symbiosis using metabolic modeling." PLOS Computational Biology 17, no. 5 (May 7, 2021): e1008983. http://dx.doi.org/10.1371/journal.pcbi.1008983.
Full textCook, Daniel J., John Whitman, Nicole Liadis, and John Cole. "Abstract P1-05-07: Spatially-resolved single-cell tumor heterogeneity captured by TumorScope biophysical modeling software using MR Imaging." Cancer Research 82, no. 4_Supplement (February 15, 2022): P1–05–07—P1–05–07. http://dx.doi.org/10.1158/1538-7445.sabcs21-p1-05-07.
Full textLavoie, Michel, Blanche Saint-Béat, Jan Strauss, Sébastien Guérin, Antoine Allard, Simon V. Hardy, Angela Falciatore, and Johann Lavaud. "Genome-Scale Metabolic Reconstruction and in Silico Perturbation Analysis of the Polar Diatom Fragilariopsis cylindrus Predicts High Metabolic Robustness." Biology 9, no. 2 (February 17, 2020): 30. http://dx.doi.org/10.3390/biology9020030.
Full textKeuls, Rachel A., Karin Kojima, Brittney Lozzi, John W. Steele, Qiuying Chen, Steven S. Gross, Richard H. Finnell, and Ronald J. Parchem. "MiR-302 Regulates Glycolysis to Control Cell-Cycle during Neural Tube Closure." International Journal of Molecular Sciences 21, no. 20 (October 13, 2020): 7534. http://dx.doi.org/10.3390/ijms21207534.
Full textFan, Yang-Yi, Laurie A. Davidson, Evelyn S. Callaway, Gus A. Wright, Stephen Safe, and Robert S. Chapkin. "A bioassay to measure energy metabolism in mouse colonic crypts, organoids, and sorted stem cells." American Journal of Physiology-Gastrointestinal and Liver Physiology 309, no. 1 (July 1, 2015): G1—G9. http://dx.doi.org/10.1152/ajpgi.00052.2015.
Full textAgius, Loranne, Josep Centelles, and Marta Cascante. "Multiple glucose 6-phosphate pools or channelling of flux in diverse pathways?" Biochemical Society Transactions 30, no. 2 (April 1, 2002): 38–43. http://dx.doi.org/10.1042/bst0300038.
Full textCovert, Markus W., Nan Xiao, Tiffany J. Chen, and Jonathan R. Karr. "Integrating metabolic, transcriptional regulatory and signal transduction models in Escherichia coli." Bioinformatics 24, no. 18 (July 10, 2008): 2044–50. http://dx.doi.org/10.1093/bioinformatics/btn352.
Full textPareek, Vidhi, Hua Tian, Nicholas Winograd, and Stephen J. Benkovic. "Metabolomics and mass spectrometry imaging reveal channeled de novo purine synthesis in cells." Science 368, no. 6488 (April 16, 2020): 283–90. http://dx.doi.org/10.1126/science.aaz6465.
Full textBanerjee, Arindam, Charles N. Birts, Matthew Darley, Rachel Parker, Alex H. Mirnezami, Jonathan West, Ramsey I. Cutress, Stephen A. Beers, Matthew J. J. Rose-Zerilli, and Jeremy P. Blaydes. "Stem cell-like breast cancer cells with acquired resistance to metformin are sensitive to inhibitors of NADH-dependent CtBP dimerization." Carcinogenesis 40, no. 7 (January 22, 2019): 871–82. http://dx.doi.org/10.1093/carcin/bgy174.
Full textHeng, Jacob S., Amir Rattner, Genevieve L. Stein-O’Brien, Briana L. Winer, Bryan W. Jones, Hilary J. Vernon, Loyal A. Goff, and Jeremy Nathans. "Hypoxia tolerance in the Norrin-deficient retina and the chronically hypoxic brain studied at single-cell resolution." Proceedings of the National Academy of Sciences 116, no. 18 (April 15, 2019): 9103–14. http://dx.doi.org/10.1073/pnas.1821122116.
Full textDelgoffe, Greg M. "Abstract IA09: Tumor cell oxidative metabolism as a barrier to antitumor immunity in melanoma." Cancer Research 80, no. 19_Supplement (October 1, 2020): IA09. http://dx.doi.org/10.1158/1538-7445.mel2019-ia09.
Full textChoi, Soohee, Suree Kim, Jiyoung Park, Seung Eun Lee, Chaewon Kim, and Dongmin Kang. "Diclofenac: A Nonsteroidal Anti-Inflammatory Drug Inducing Cancer Cell Death by Inhibiting Microtubule Polymerization and Autophagy Flux." Antioxidants 11, no. 5 (May 20, 2022): 1009. http://dx.doi.org/10.3390/antiox11051009.
Full textZhang, Yiru, Trang Nguyen, Junfei Zhao, Enyuan Shang, Consuelo Torrini, Peter D. Canoll, Georg Karpel-Massler, and Markus Siegelin. "CBMT-15. MET INHIBITION DRIVES PGC1A DEPENDENT METABOLIC REPROGRAMMING AND ELICITS UNIQUE METABOLIC VULNERABILITIES IN GLIOBLASTOMA." Neuro-Oncology 21, Supplement_6 (November 2019): vi36. http://dx.doi.org/10.1093/neuonc/noz175.137.
Full textOshima, Nobu, Yuki Aisu, Shigeo Hisamori, Shigeru Tsunoda, Hiroki Hashida, Kenji Uryuhara, Hiroyuki Kobayashi, et al. "Abstract 6222: Comprehensive monitoring of pyruvate metabolism in cancer cells and tumors reveals vulnerability to metabolic inhibition therapy with small molecules." Cancer Research 82, no. 12_Supplement (June 15, 2022): 6222. http://dx.doi.org/10.1158/1538-7445.am2022-6222.
Full textLand, S. C., R. H. Sanger, and P. J. S. Smith. "O2 availability modulates transmembrane Ca2+ flux via second-messenger pathways in anoxia-tolerant hepatocytes." Journal of Applied Physiology 82, no. 3 (March 1, 1997): 776–83. http://dx.doi.org/10.1152/jappl.1997.82.3.776.
Full textGwon, Hyeokjo, Kitae Park, Soon-Chun Chung, Ryoung-Hee Kim, Jin Kyu Kang, Sang Min Ji, Nag-Jong Kim, et al. "A safe and sustainable bacterial cellulose nanofiber separator for lithium rechargeable batteries." Proceedings of the National Academy of Sciences 116, no. 39 (September 9, 2019): 19288–93. http://dx.doi.org/10.1073/pnas.1905527116.
Full textMun, Edward C., Kevin J. Tally, and Jeffrey B. Matthews. "Characterization and regulation of adenosine transport in T84 intestinal epithelial cells." American Journal of Physiology-Gastrointestinal and Liver Physiology 274, no. 2 (February 1, 1998): G261—G269. http://dx.doi.org/10.1152/ajpgi.1998.274.2.g261.
Full textBayley, Nicholas, Christopher Tse, Henan Zhu, Lisa Ta, Lynn Baufeld, Laura Gosa, Weihong Yan, et al. "EPCO-10. INTRATUMORAL HETEROGENEITY OF ENVIRONMENT-INDUCED EXPRESSION PROGRAMS IN GLIOMA PATIENTS AND DERIVED MODEL SYSTEMS." Neuro-Oncology 23, Supplement_6 (November 2, 2021): vi3. http://dx.doi.org/10.1093/neuonc/noab196.009.
Full textRashidi, Aida, Alex Cordero, Brandyn Castro, David Hou, Mark Dapash, Peng Zhang, Yu Han, et al. "TAMI-25. UPREGULATION OF CREATINE METABOLISM BY MYELOID CELLS RESULTS IN GLIOBLASTOMA PROGRESSION." Neuro-Oncology 23, Supplement_6 (November 2, 2021): vi203. http://dx.doi.org/10.1093/neuonc/noab196.809.
Full textWang, Jenny, and Jonathan Zippin. "2173." Journal of Clinical and Translational Science 1, S1 (September 2017): 2. http://dx.doi.org/10.1017/cts.2017.25.
Full textGoretzki, Alexandra, Yen-Ju Lin, Jennifer Zimmermann, Hannah Rainer, Ann-Christine Junker, Sonja Wolfheimer, Stefan Vieths, Stephan Scheurer, and Stefan Schülke. "Role of Glycolysis and Fatty Acid Synthesis in the Activation and T Cell-Modulating Potential of Dendritic Cells Stimulated with a TLR5-Ligand Allergen Fusion Protein." International Journal of Molecular Sciences 23, no. 20 (October 21, 2022): 12695. http://dx.doi.org/10.3390/ijms232012695.
Full textWagner, Tristan, Gwénaëlle André-Leroux, Valérie Hindie, Nathalie Barilone, María-Natalia Lisa, Sylviane Hoos, Bertrand Raynal, et al. "Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling." Science Signaling 12, no. 580 (May 7, 2019): eaav9504. http://dx.doi.org/10.1126/scisignal.aav9504.
Full textKAVANAGH, Kathryn L., Mario KLIMACEK, Bernd NIDETZKY, and David K. WILSON. "Structure of xylose reductase bound to NAD+ and the basis for single and dual co-substrate specificity in family 2 aldo-keto reductases." Biochemical Journal 373, no. 2 (July 15, 2003): 319–26. http://dx.doi.org/10.1042/bj20030286.
Full textLeyn, Semen A., Xiaoqing Li, Qingxiang Zheng, Pavel S. Novichkov, Samantha Reed, Margaret F. Romine, James K. Fredrickson, Chen Yang, Andrei L. Osterman, and Dmitry A. Rodionov. "Control of Proteobacterial Central Carbon Metabolism by the HexR Transcriptional Regulator." Journal of Biological Chemistry 286, no. 41 (August 17, 2011): 35782–94. http://dx.doi.org/10.1074/jbc.m111.267963.
Full textRashidi Othman, Norazian Mohd. Hassan, Ainaa Eliah Abu Bakar, Nur Hidayah Noh, Nurrulhidayah Ahmad Fadzillah, and Noraini Mahmad. "Manipulation of Environmental Stress Towards Lutein Production in Chlorella fusca Cell Culture." Journal of Pharmacy and Nutrition Sciences 9, no. 5 (January 5, 2019): 251–57. http://dx.doi.org/10.29169/1927-5951.2019.09.05.3.
Full textForte, Dorian, Roberto Maria Pellegrino, Francesco Fabbri, Ivan Vannini, Samantha Bruno, Giulia Corradi, Rafael J. Argüello, et al. "Circulating Extracellular Vesicles from Acute Myeloid Leukemia Patients Drive Distinct Metabolic Profile of Leukemic Cells and Reveal Crucial Lipidomic Biomarkers." Blood 138, Supplement 1 (November 5, 2021): 3471. http://dx.doi.org/10.1182/blood-2021-150339.
Full textCzechowski, Tomasz, Tony R. Larson, Theresa M. Catania, David Harvey, Geoffrey D. Brown, and Ian A. Graham. "Artemisia annua mutant impaired in artemisinin synthesis demonstrates importance of nonenzymatic conversion in terpenoid metabolism." Proceedings of the National Academy of Sciences 113, no. 52 (December 7, 2016): 15150–55. http://dx.doi.org/10.1073/pnas.1611567113.
Full textLiu, Yuxuan, Lucille Stuani, Dorra Jedoui, Milton Merchant, Astraea Jager, Jolanda Sarno, Charles G. Mullighan, Felix J. Hartmann, Sean Bendall, and Kara L. Davis. "Inhibition of Pre-BCR Signaling Mediates a Metabolic Switch in B-Cell Progenitor Acute Lymphoblastic Leukemia." Blood 138, Supplement 1 (November 5, 2021): 615. http://dx.doi.org/10.1182/blood-2021-145956.
Full textSanchez, Anthony M. J., Henri Bernardi, Guillaume Py, and Robin B. Candau. "Autophagy is essential to support skeletal muscle plasticity in response to endurance exercise." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 307, no. 8 (October 15, 2014): R956—R969. http://dx.doi.org/10.1152/ajpregu.00187.2014.
Full textHeart, Emma, and Peter J. S. Smith. "Rhythm of the β-cell oscillator is not governed by a single regulator: multiple systems contribute to oscillatory behavior." American Journal of Physiology-Endocrinology and Metabolism 292, no. 5 (May 2007): E1295—E1300. http://dx.doi.org/10.1152/ajpendo.00648.2006.
Full textIssitt, Theo, Sean T. Sweeney, William J. Brackenbury, and Kelly R. Redeker. "Sampling and Analysis of Low-Molecular-Weight Volatile Metabolites in Cellular Headspace and Mouse Breath." Metabolites 12, no. 7 (June 27, 2022): 599. http://dx.doi.org/10.3390/metabo12070599.
Full textKlein, Vivien Jessica, Marta Irla, Marina Gil López, Trygve Brautaset, and Luciana Fernandes Brito. "Unravelling Formaldehyde Metabolism in Bacteria: Road towards Synthetic Methylotrophy." Microorganisms 10, no. 2 (January 20, 2022): 220. http://dx.doi.org/10.3390/microorganisms10020220.
Full textSchwartz, Laurent, Luc Benichou, Jules Schwartz, Maxime Pontié, and Marc Henry. "Is the Second Law of Thermodynamics Able to Classify Drugs?" Substantia 6, no. 1 (March 7, 2022): 37–47. http://dx.doi.org/10.36253/substantia-1364.
Full textRosenberg, Evgenia, Valeria Voevoda, Hila Magen, Olga Ostrovsky, Avichai Shimoni, Amnon Peled, Arnon Nagler, and Katia Beider. "Venetoclax Reverses Metabolic Reprogramming Induced By S1P Modulator FTY720, Suppresses Oxidative Phosphorylation and Synergistically Targets Multiple Myeloma." Blood 138, Supplement 1 (November 5, 2021): 1195. http://dx.doi.org/10.1182/blood-2021-149372.
Full textMertz, Joseph L., Shisheng Sun, Bojiao Yin, Yingwei Hu, Rahul Bhattacharya, Michael J. Bettenbaugh, Kevin J. Yarema, and Hui Zhang. "Comparison of Three Glycoproteomic Methods for the Analysis of the Secretome of CHO Cells Treated with 1,3,4-O-Bu3ManNAc." Bioengineering 7, no. 4 (November 10, 2020): 144. http://dx.doi.org/10.3390/bioengineering7040144.
Full textStern, D., J. Brett, K. Harris, and P. Nawroth. "Participation of endothelial cells in the protein C-protein S anticoagulant pathway: the synthesis and release of protein S." Journal of Cell Biology 102, no. 5 (May 1, 1986): 1971–78. http://dx.doi.org/10.1083/jcb.102.5.1971.
Full textGeorge, Sajan, and Heidi Abrahamse. "Redox Potential of Antioxidants in Cancer Progression and Prevention." Antioxidants 9, no. 11 (November 20, 2020): 1156. http://dx.doi.org/10.3390/antiox9111156.
Full textSengupta, Annesha, Prem Pritam, Damini Jaiswal, Anindita Bandyopadhyay, Himadri B. Pakrasi, and Pramod P. Wangikar. "Photosynthetic Co-production of Succinate and Ethylene in a Fast-Growing Cyanobacterium, Synechococcus elongatus PCC 11801." Metabolites 10, no. 6 (June 16, 2020): 250. http://dx.doi.org/10.3390/metabo10060250.
Full textKrömer, Jens Olaf, Elmar Heinzle, Hartwig Schröder, and Christoph Wittmann. "Accumulation of Homolanthionine and Activation of a Novel Pathway for Isoleucine Biosynthesis in Corynebacterium glutamicum McbR Deletion Strains." Journal of Bacteriology 188, no. 2 (January 15, 2006): 609–18. http://dx.doi.org/10.1128/jb.188.2.609-618.2006.
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