Journal articles on the topic 'Sin1'
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McCarthy, Nicola. "An original SIN1." Nature Reviews Cancer 13, no. 12 (November 22, 2013): 823. http://dx.doi.org/10.1038/nrc3641.
Full textKruger, W., and I. Herskowitz. "A negative regulator of HO transcription, SIN1 (SPT2), is a nonspecific DNA-binding protein related to HMG1." Molecular and Cellular Biology 11, no. 8 (August 1991): 4135–46. http://dx.doi.org/10.1128/mcb.11.8.4135-4146.1991.
Full textKruger, W., and I. Herskowitz. "A negative regulator of HO transcription, SIN1 (SPT2), is a nonspecific DNA-binding protein related to HMG1." Molecular and Cellular Biology 11, no. 8 (August 1991): 4135–46. http://dx.doi.org/10.1128/mcb.11.8.4135.
Full textXu, Yanyan, Xue Chen, and Junling Liu. "The Critical Roles of SIN1 in Platelet Activation and Myocardial Infarction." Blood 128, no. 22 (December 2, 2016): 3715. http://dx.doi.org/10.1182/blood.v128.22.3715.3715.
Full textRay, A., J. D. Lang, T. Golden, and S. Ray. "SHORT INTEGUMENT (SIN1), a gene required for ovule development in Arabidopsis, also controls flowering time." Development 122, no. 9 (September 1, 1996): 2631–38. http://dx.doi.org/10.1242/dev.122.9.2631.
Full textZhou, Yang. "Exploring the emergence of the postverbal sin1 先 in Cantonese." Language and Linguistics / 語言暨語言學 19, no. 2 (March 15, 2018): 333–75. http://dx.doi.org/10.1075/lali.00012.zho.
Full textCameron, Angus J. M., Mark D. Linch, Adrian T. Saurin, Cristina Escribano, and Peter J. Parker. "mTORC2 targets AGC kinases through Sin1-dependent recruitment." Biochemical Journal 439, no. 2 (September 28, 2011): 287–97. http://dx.doi.org/10.1042/bj20110678.
Full textCastel, Pau, Srisathiyanarayanan Dharmaiah, Matthew J. Sale, Simon Messing, Gabrielle Rizzuto, Antonio Cuevas-Navarro, Alice Cheng, et al. "RAS interaction with Sin1 is dispensable for mTORC2 assembly and activity." Proceedings of the National Academy of Sciences 118, no. 33 (August 11, 2021): e2103261118. http://dx.doi.org/10.1073/pnas.2103261118.
Full textPérez-Martín, José, and Alexander D. Johnson. "The C-Terminal Domain of Sin1 Interacts with the SWI-SNF Complex in Yeast." Molecular and Cellular Biology 18, no. 7 (July 1, 1998): 4157–64. http://dx.doi.org/10.1128/mcb.18.7.4157.
Full textZdetsis, Aristides D. "Fluxional and aromatic behavior in small magic silicon clusters: A full ab initio study of Sin, Sin1−, Sin2−, and Sin1+, n=6, 10 clusters." Journal of Chemical Physics 127, no. 1 (July 7, 2007): 014314. http://dx.doi.org/10.1063/1.2746030.
Full textYuan, Yuanyang, Bangfen Pan, Haipeng Sun, Guoqiang Chen, Bing Su, and Ying Huang. "Characterization of Sin1 Isoforms Reveals an mTOR-Dependent and Independent Function of Sin1γ." PLOS ONE 10, no. 8 (August 11, 2015): e0135017. http://dx.doi.org/10.1371/journal.pone.0135017.
Full textOuyang, Xinxing, Yuheng Han, Guojun Qu, Man Li, Ningbo Wu, Hongzhi Liu, Omotooke Arojo, et al. "Metabolic regulation of T cell development by Sin1–mTORC2 is mediated by pyruvate kinase M2." Journal of Molecular Cell Biology 11, no. 2 (November 14, 2018): 93–106. http://dx.doi.org/10.1093/jmcb/mjy065.
Full textRuan, Chun, Xinxing Ouyang, Hongzhi Liu, Song Li, Jingsi Jin, Weiyi Tang, Yu Xia, and Bing Su. "Sin1-mediated mTOR signaling in cell growth, metabolism and immune response." National Science Review 6, no. 6 (November 1, 2019): 1149–62. http://dx.doi.org/10.1093/nsr/nwz171.
Full textZohar, Keren, Elyad Lezmi, Tsiona Eliyahu, and Michal Linial. "Ladostigil Attenuates Induced Oxidative Stress in Human Neuroblast-like SH-SY5Y Cells." Biomedicines 9, no. 9 (September 17, 2021): 1251. http://dx.doi.org/10.3390/biomedicines9091251.
Full textChi, Hongbo. "Sin1–mTORC2 signaling drives glycolysis of developing thymocytes." Journal of Molecular Cell Biology 11, no. 2 (November 29, 2018): 91–92. http://dx.doi.org/10.1093/jmcb/mjy078.
Full textYuan, Hai-Xin, and Kun-Liang Guan. "The SIN1-PH Domain Connects mTORC2 to PI3K." Cancer Discovery 5, no. 11 (November 2015): 1127–29. http://dx.doi.org/10.1158/2159-8290.cd-15-1125.
Full textXu, Hui, Tong Cao, Xiaoqing Zhang, Ying Shi, Qing Zhang, Shuo Chai, Li Yu, et al. "Nitidine Chloride Inhibits SIN1 Expression in Osteosarcoma Cells." Molecular Therapy - Oncolytics 12 (March 2019): 224–34. http://dx.doi.org/10.1016/j.omto.2019.01.005.
Full textPollard, K. J., and C. L. Peterson. "Role for ADA/GCN5 products in antagonizing chromatin-mediated transcriptional repression." Molecular and Cellular Biology 17, no. 11 (November 1997): 6212–22. http://dx.doi.org/10.1128/mcb.17.11.6212.
Full textKolenko, Yulia G., Iryna A. Volovyk, Natalia V. Bidenko, Konstantin O. Mialkivskyi, and Iryna M. Tkachenko. "BUCCAL CELL MICRONUCLEI AMONG PATIENTS WITH ORAL LEUKOPLAKIA." Wiadomości Lekarskie 75, no. 7 (2022): 1713–17. http://dx.doi.org/10.36740/wlek202207119.
Full textKitamura, Nao, Nobuyuki Fujiwara, Koji Hayakawa, Takashi Ohama, and Koichi Sato. "Protein phosphatase 6 promotes neurite outgrowth by dephosphorylating SIN1." Proceedings for Annual Meeting of The Japanese Pharmacological Society 95 (2022): 1—SS—51. http://dx.doi.org/10.1254/jpssuppl.95.0_1-ss-51.
Full textZohar, Keren, Eliran Giladi, Tsiona Eliyahu, and Michal Linial. "Oxidative Stress and Its Modulation by Ladostigil Alter the Expression of Abundant Long Non-Coding RNAs in SH-SY5Y Cells." Non-Coding RNA 8, no. 6 (October 25, 2022): 72. http://dx.doi.org/10.3390/ncrna8060072.
Full textWilkinson, M. G. "Sin1: an evolutionarily conserved component of the eukaryotic SAPK pathway." EMBO Journal 18, no. 15 (August 2, 1999): 4210–21. http://dx.doi.org/10.1093/emboj/18.15.4210.
Full textShpungin, S., A. Liberzon, H. Bangio, E. Yona, and D. J. Katcoff. "Association of yeast SIN1 with the tetratrico peptide repeats of CDC23." Proceedings of the National Academy of Sciences 93, no. 16 (August 6, 1996): 8274–77. http://dx.doi.org/10.1073/pnas.93.16.8274.
Full textYang, Guang, Danielle S. Murashige, Sean J. Humphrey, and David E. James. "A Positive Feedback Loop between Akt and mTORC2 via SIN1 Phosphorylation." Cell Reports 12, no. 6 (August 2015): 937–43. http://dx.doi.org/10.1016/j.celrep.2015.07.016.
Full textLefebvre, L., and M. Smith. "Mutational and functional analysis of dominant SPT2 (SIN1) suppressor alleles in Saccharomyces cerevisiae." Molecular and Cellular Biology 13, no. 9 (September 1993): 5393–407. http://dx.doi.org/10.1128/mcb.13.9.5393-5407.1993.
Full textLefebvre, L., and M. Smith. "Mutational and functional analysis of dominant SPT2 (SIN1) suppressor alleles in Saccharomyces cerevisiae." Molecular and Cellular Biology 13, no. 9 (September 1993): 5393–407. http://dx.doi.org/10.1128/mcb.13.9.5393.
Full textChen, Chien-Hung, Vladimir Kiyan, Assylbek A. Zhylkibayev, Dubek Kazyken, Olga Bulgakova, Kent E. Page, Rakhmet I. Bersimbaev, Eric Spooner, and Dos D. Sarbassov. "Autoregulation of the Mechanistic Target of Rapamycin (mTOR) Complex 2 Integrity Is Controlled by an ATP-dependent Mechanism." Journal of Biological Chemistry 288, no. 38 (August 8, 2013): 27019–30. http://dx.doi.org/10.1074/jbc.m113.498055.
Full textDumortier, Julien G., and Nicolas B. David. "The TORC2 Component, Sin1, Controls Migration of Anterior Mesendoderm during Zebrafish Gastrulation." PLOS ONE 10, no. 2 (February 24, 2015): e0118474. http://dx.doi.org/10.1371/journal.pone.0118474.
Full textWang, Jian-Qiu, Jian-Hong Chen, Yen-Chung Chen, Mei-Yu Chen, Chia-Ying Hsieh, Shu-Chun Teng, and Kou-Juey Wu. "Interaction between NBS1 and the mTOR/Rictor/SIN1 Complex through Specific Domains." PLoS ONE 8, no. 6 (June 6, 2013): e65586. http://dx.doi.org/10.1371/journal.pone.0065586.
Full textSchroder, Wayne, Nicole Cloonan, Gillian Bushell, and Tom Sculley. "Alternative polyadenylation and splicing of mRNAs transcribed from the human Sin1 gene." Gene 339 (September 2004): 17–23. http://dx.doi.org/10.1016/j.gene.2004.07.001.
Full textYingying, Xiang, Wang Caijuan, Yue Yenan, Tang Yuqin, Cai Xueqin, and Wu Zhongming. "The Effect of SIN1 and Microtubules on Insulin Induced PKC ζ Activation." Medical Science Monitor 23 (July 28, 2017): 3666–72. http://dx.doi.org/10.12659/msm.905555.
Full textWang, Q., J. Zhu, Y.-W. Wang, Y. Dai, Y.-L. Wang, C. Wang, J. Liu, A. Baker, N. H. Colburn, and H.-S. Yang. "Tumor suppressor Pdcd4 attenuates Sin1 translation to inhibit invasion in colon carcinoma." Oncogene 36, no. 45 (July 10, 2017): 6225–34. http://dx.doi.org/10.1038/onc.2017.228.
Full textOkuhashi, Yuki, Mai Itoh, Nobuo Nara, and Shuji Tohda. "Effects of NOTCH Knockdown on the Proliferation and mTOR Signaling of T-ALL and AML Cell Lines." Blood 122, no. 21 (November 15, 2013): 1396. http://dx.doi.org/10.1182/blood.v122.21.1396.1396.
Full textBaxter, Bonnie K., and Elizabeth A. Craig. "Suppression of an Hsp70 Mutant Phenotype in Saccharomyces cerevisiae through Loss of Function of the Chromatin Component Sin1p/Spt2p." Journal of Bacteriology 180, no. 24 (December 15, 1998): 6484–92. http://dx.doi.org/10.1128/jb.180.24.6484-6492.1998.
Full textLi, Man, Adam S. Lazorchak, Xinxing Ouyang, Huihui Zhang, Hongzhi Liu, Omotooke A. Arojo, Lichong Yan, et al. "Sin1/mTORC2 regulate B cell growth and metabolism by activating mTORC1 and Myc." Cellular & Molecular Immunology 16, no. 9 (January 31, 2019): 757–69. http://dx.doi.org/10.1038/s41423-018-0185-x.
Full textKatcoff, Don J., Eyal Yona, Gitit Hershkovits, Hadas Friedman, Yael Cohen, and Orly Dgany. "SIN1 interacts with a protein that binds the URS1 region of the yeastHOgene." Nucleic Acids Research 21, no. 22 (1993): 5101–9. http://dx.doi.org/10.1093/nar/21.22.5101.
Full textLazorchak, Adam S., Dou Liu, Valeria Facchinetti, Annarita Di Lorenzo, William C. Sessa, David G. Schatz, and Bing Su. "Sin1-mTORC2 Suppresses rag and il7r Gene Expression through Akt2 in B Cells." Molecular Cell 39, no. 3 (August 2010): 433–43. http://dx.doi.org/10.1016/j.molcel.2010.07.031.
Full textSchroder, Wayne A., Marion Buck, Nicole Cloonan, John F. Hancock, Andreas Suhrbier, Tom Sculley, and Gillian Bushell. "Human Sin1 contains Ras-binding and pleckstrin homology domains and suppresses Ras signalling." Cellular Signalling 19, no. 6 (June 2007): 1279–89. http://dx.doi.org/10.1016/j.cellsig.2007.01.013.
Full textXu, Jiangfeng, Xuedong Li, Hao Yang, RuiMin Chang, Chenchen Kong, and Lianyue Yang. "SIN1 promotes invasion and metastasis of hepatocellular carcinoma by facilitating epithelial-mesenchymal transition." Cancer 119, no. 12 (April 5, 2013): 2247–57. http://dx.doi.org/10.1002/cncr.28023.
Full textPearce, Laura R., Xu Huang, Jérôme Boudeau, Rafał Pawłowski, Stephan Wullschleger, Maria Deak, Adel F. M. Ibrahim, Robert Gourlay, Mark A. Magnuson, and Dario R. Alessi. "Identification of Protor as a novel Rictor-binding component of mTOR complex-2." Biochemical Journal 405, no. 3 (July 13, 2007): 513–22. http://dx.doi.org/10.1042/bj20070540.
Full textJacinto, Estela, Valeria Facchinetti, Dou Liu, Nelyn Soto, Shiniu Wei, Sung Yun Jung, Qiaojia Huang, Jun Qin, and Bing Su. "SIN1/MIP1 Maintains rictor-mTOR Complex Integrity and Regulates Akt Phosphorylation and Substrate Specificity." Cell 127, no. 1 (October 2006): 125–37. http://dx.doi.org/10.1016/j.cell.2006.08.033.
Full textLiu, Pengda, Wenjian Gan, Hiroyuki Inuzuka, Adam S. Lazorchak, Daming Gao, Omotooke Arojo, Dou Liu, et al. "Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis." Nature Cell Biology 15, no. 11 (October 27, 2013): 1340–50. http://dx.doi.org/10.1038/ncb2860.
Full textTavaluc, Raluca, Howard Herman, Juan Lin, and Melin Tan. "Does Reinke’s Edema Grade Determine Premalignant Potential?" Annals of Otology, Rhinology & Laryngology 127, no. 11 (September 6, 2018): 812–16. http://dx.doi.org/10.1177/0003489418796529.
Full textYang, Q., K. Inoki, T. Ikenoue, and K. L. Guan. "Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity." Genes & Development 20, no. 20 (October 15, 2006): 2820–32. http://dx.doi.org/10.1101/gad.1461206.
Full textKroczynska, Barbara, Gavin T. Blyth, Robert L. Rafidi, Beata Majchrzak-Kita, Lucy Xu, Diana Saleiro, Ewa M. Kosciuczuk, et al. "Central Regulatory Role for SIN1 in Interferon γ (IFNγ) Signaling and Generation of Biological Responses." Journal of Biological Chemistry 292, no. 11 (February 7, 2017): 4743–52. http://dx.doi.org/10.1074/jbc.m116.757666.
Full textChang, Xing, Adam S. Lazorchak, Dou Liu, and Bing Su. "Sin1 regulates Treg-cell development but is not required for T-cell growth and proliferation." European Journal of Immunology 42, no. 6 (June 2012): 1639–47. http://dx.doi.org/10.1002/eji.201142066.
Full textLiu, Pengda, Jianping Guo, Wenjian Gan, and Wenyi Wei. "Dual phosphorylation of Sin1 at T86 and T398 negatively regulates mTORC2 complex integrity and activity." Protein & Cell 5, no. 3 (January 31, 2014): 171–77. http://dx.doi.org/10.1007/s13238-014-0021-8.
Full textGhosh, D., G. P. Srivastava, D. Xu, L. C. Schulz, and R. M. Roberts. "A link between SIN1 (MAPKAP1) and poly(rC) binding protein 2 (PCBP2) in counteracting environmental stress." Proceedings of the National Academy of Sciences 105, no. 33 (August 7, 2008): 11673–78. http://dx.doi.org/10.1073/pnas.0803182105.
Full textLiu, Pengda, Wenjian Gan, Hiroyuki Inuzuka, Adam S. Lazorchak, Daming Gao, Omotooke Arojo, Dou Liu, et al. "Author Correction: Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis." Nature Cell Biology 21, no. 5 (February 19, 2019): 662–63. http://dx.doi.org/10.1038/s41556-019-0280-y.
Full textKaur, Surinder, Barbara Kroczynska, Bhumika Sharma, Antonella Sassano, Ahmet Dirim Arslan, Beata Majchrzak-Kita, Brady L. Stein, et al. "Critical Roles for Rictor/Sin1 Complexes in Interferon-dependent Gene Transcription and Generation of Antiproliferative Responses." Journal of Biological Chemistry 289, no. 10 (January 27, 2014): 6581–91. http://dx.doi.org/10.1074/jbc.m113.537852.
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