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1

Tran, Nguyen-Phuong-Dung, and Ming-Chien Yang. "Synthesis and Characterization of Silicone Contact Lenses Based on TRIS-DMA-NVP-HEMA Hydrogels." Polymers 11, no. 6 (May 31, 2019): 944. http://dx.doi.org/10.3390/polym11060944.

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In this study, silicone-based hydrogel contact lenses were prepared by the polymerization of 3-(methacryloyloxy)propyltris(trimethylsiloxy)silane (TRIS), N,N-dimethylacrylamide (DMA), 1-vinyl-2-pyrrolidinone (NVP), and 2-hydroxyethylmethacrylate (HEMA). The properties of silicone hydrogel lenses were analyzed based on the methods such as equilibrium water content, oxygen permeability, optical transparency, contact angle, mechanical test, protein adsorption, and cell toxicity. The results showed that the TRIS content in all formulations increased the oxygen permeability and decreased the equilibrium water content, while both DMA and NVP contributed the hydrophilicity of the hydrogels. The maximum value of oxygen permeability was 74.9 barrers, corresponding to an equilibrium water content of 44.5% as well as a contact angle of 82°. Moreover, L929 fibroblasts grew on all these hydrogels, suggesting non-cytotoxicity. In general, the silicone hydrogels in this work exhibited good oxygen permeability, stiffness, and optical transparency as well as anti-protein adsorption. Hence, these silicone hydrogel polymers would be feasible for making contact lens.
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2

Muller, Guy-Henri. "Hydrogel-Filled Mammary Prosthesis." American Journal of Cosmetic Surgery 15, no. 3 (September 1998): 259–62. http://dx.doi.org/10.1177/074880689801500306.

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Introduction: The silicone breast implant controversy and the moratorium on the use of silicone-gel-filled breast implants in the U.S., Canada, and France has led to a search for substitutes for silicone-gel implants that are safe, pliable, and still firm enough to hold its shape. Hydrogel is being evaluated as an alternative to silicone gel for filling breast implants. Materials and Methods: Eighteen hundred ninety hydrogel-filled breast implants were inserted into patients in France and Italy between 1992 and 1993. The postoperative results of these procedures were reviewed. Results: Twelve implant ruptures occurred at the time of insertion secondary to too small an incision and lack of prewarming of the implant. Two ruptures went unnoticed and were satisfactorily resolved with a revision of the first procedure. One capsule contracture occurred within one year. Visual results according to patients and surgeons were satisfactory. The palpable results are less favorable than silicone-gel implants, but better than saline-filled implants. Discussion: Hydrogel is biocompatible. The breakdown products of the implant filler, if they migrate outside the shell, should not be toxic. Because hydrogel is a biomaterial filler to which water is added to reach an equilibrium point, it mimics the consistency of living tissue. Conclusions: Hydrogel appears to be a favorable substitute for silicone gel.
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3

Shin, Su-Mi, and A.-Young Sung. "Preparation and Analysis of Functional Silicone Hydrogel Lenses Containing ZrO2 and Antimony Tin Oxide Nanoparticles." Journal of Nanoscience and Nanotechnology 21, no. 9 (September 1, 2021): 4649–53. http://dx.doi.org/10.1166/jnn.2021.19291.

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This study prepared silicone hydrogel ophthalmic lenses using 2-hydroxyethylmethacrylate (HEMA), synthesized silicone monomer (SID), dimethylarsinic acid (DMA), N-hydroxyethyl acrylamide (HEA), ethylene glycol dimethacrylate (a crosslinking agent, EGDMA), and azobisisobutyronitrile (an initiator, AIBN). Also, Zirconium oxide (ZrO2), antimony tin oxide (ATO) nanoparticles were added to the silicone hydrogel material to analyze the characteristics of the nanoparticles. The mixture was heated at 130 °C for 2 hours to produce the ophthalmic contact lens by cast mould method. As a result, the manufactured silicone hydrogel lens was prepared having high oxygen permeability and tensile strength while satisfying the basic requirements of ophthalmic hydrogel lens materials. Also, the addition of ZrO2 NPs increased tensile strength of the manufactured lens, and ATO NPs were found to improve wettability. Therefore, ZrO2 and ATO nanoparticles can be used effectively as additives for functional ophthalmic silicone hydrogel lenses.
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4

Shi, Xinfeng, Charlie Chen, Ronghua Liu, Paul Lee, Steve Diamanti, and Paul Richardson. "Silicone hydrogel properties based upon effective silicone chemistry." Contact Lens and Anterior Eye 41 (June 2018): S7. http://dx.doi.org/10.1016/j.clae.2018.04.100.

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5

Peev, Nikola. "WETTABILITY – ANOTHER PARAMETER FOR GOOD FITTING OF A SILICONE-HYDROGEL DAILY DISPOSABLE CONTACT LENS." Teacher of the future 31, no. 4 (June 5, 2019): 1001–4. http://dx.doi.org/10.35120/kij31041001p.

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The modern world is very fast and dynamic. Consumer requirements rise to every commodity part of their everyday life - food, clothing, cosmetics, and medical devices. Eye care and eye health are also part of them. Companies producing contact lenses work daily to improve the safety and comfort of wearing, as well as on the technical characteristics of the material (type of material, wear time, module, Dk / t etc.). Silicon hydrogel contact lenses (SiHy) were introduced almost two decades ago. At that time it was estimated that there are about 70 million contact lenses all over the world. Since then, their number has doubled and a significant majority now have silicone-hydrogel contact lenses, resulting in a steady and noticeable reduction in the number of regular hydrogel lenses. When the first one-day silicon-hydrogel contact lenses were introduced in 2008, they were announced as breakthroughs in technology. When they were introduced to the market, they were presented in spherical, toric and multifocal designs, which led to a significant increase in the use / prescription of silicon-hydrogel daily disposable contact lenses. A survey conducted in 2014 by the International Consortium illustrates this point. Although, according to this study, the use of SiHy contact lenses varies widely across the world. In the United States, Canada, Australia and the United Kingdom, four to six times more patients were fitted with silicone-hydrogel CLs compared to hydrogels in 2014 and in each country, daily disposable SiHy contact lenses were prescribed with a larger frequency compared to daily disposable hydrogel lenses. It is important to make a good fit to ensure and increase the comfort of wearing contact lenses. In addition to some of the standard fitting techniques such as: keratometry and choice of base curve of the lens; size and eccentricity; an assessment of the mobility of a lens placed in the eye - look positions, mobility, push up test, can be added and the wetting of the contact lens. Even in perfect fit, if the lens does not interact well with the tear film, it would lead to complaints and discomfort in the patient. The degree of wetting is determined by the balance between adhesive and cohesive forces acting on the surface of the lens. CLs, which can support full wetting, allow a tight coating of the tear film, a smooth recovery of the tear layer after eyelid opening and good visual acuity. The interaction between CL, eye surface and tear film is vital to their successful fit. It has long been known that both the organic and inorganic components of the tear film and anterior surface of the eye can deposit deposits on the contact lenses. There are various non-invasive methods for assessing the tear film and, above all, the lipid layer. Some of these are Non invasive breakup time (NIBUT) and specular biomicroscopy. In the present work we will look at daily disposable silicone-hydrogel contact lenses that have been tested in vivo for good wetting, stability and good regeneration of the tear film.
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Krysztofiak, Katarzyna, Kamila Ciężar, and Mikołaj Kościński. "Raman Imaging of Layered Soft Contact Lenses." Journal of Applied Biomaterials & Functional Materials 15, no. 2 (April 2017): 149–52. http://dx.doi.org/10.5301/jabfm.5000329.

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Background Daily disposable contact lenses are gaining in popularity among practitioners and wearers for the improved ocular health and subjective outcomes they offer. Recently a novel daily disposable contact lens material with water gradient technology was introduced. Delefilcon A lenses consist of a 33% water content silicone hydrogel core and an outer hydrogel layer which is totally free of silicone and contains 80% water. Methods The aim of the present study was to confirm the layered structure of delefilcon A contact lenses. Thickness of hydrogel coating on the silicone hydrogel core was assessed using Raman spectroscopy. To investigate the layered structure of the material, depth spectra of the lenses were recorded. Results The results obtained suggest that at about 6 μm a boundary between the hydrogel layer and silicone hydrogel core exists, which is in good agreement with the manufacturer's data. Conclusions Data collected in this experiment confirm a water gradient at the delefilcon A lens surface.
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7

Pulliero, Alessandra, Aldo Profumo, Camillo Rosano, Alberto Izzotti, and Sergio Claudio Saccà. "Therapeutic Hydrogel Lenses and the Antibacterial and Antibiotic Drugs Release." Applied Sciences 11, no. 4 (February 22, 2021): 1931. http://dx.doi.org/10.3390/app11041931.

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The aim of this research was to evaluate the effects of different lens types on the availability and efficacy of anti-inflammatory and antibiotic drugs. Three lens types were examined: (1) nonionic hydrogel lenses; (2) ionic hydrogel lenses; and (3) silicone hydrogel lenses. The lenses were incubated with (a) dexamethasone; (b) betamethasone; (c) bromophenacyl bromide; and (d) chloramphenicol. Drug availability was quantified by gradient HPLC, and chloramphenicol antibacterial activity was quantified by testing the inhibition of Salmonella typhimurium growth on agar. The lens allowing the most abundant passage of betamethasone was the ionic hydrogel lens, followed by the silicone hydrogel lens and nonionic hydrogel lens. The lens allowing the most abundant passage of dexamethasone was the ionic hydrogel lens, but only at 0.5 h and 1 h. Regarding chloramphenicol, the ionic hydrogel lens and silicone hydrogel lens allowed more abundant passage than the nonionic hydrogel lens. These results highlight the relevance of adapting lenses to anti-inflammatory therapy, thus allowing a personalized medical approach.
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8

Rex, Jessica, Scott Perry, and Jessie Lemp. "Concentrations of silicon at silicone hydrogel contact lens surfaces." Contact Lens and Anterior Eye 41 (June 2018): S6. http://dx.doi.org/10.1016/j.clae.2018.04.097.

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9

Nichols, Jason J. "Deposition on Silicone Hydrogel Lenses." Eye & Contact Lens: Science & Clinical Practice 39, no. 1 (January 2013): 19–22. http://dx.doi.org/10.1097/icl.0b013e318275305b.

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10

Keir, Nancy, and Lyndon Jones. "Wettability and Silicone Hydrogel Lenses." Eye & Contact Lens: Science & Clinical Practice 39, no. 1 (January 2013): 99–107. http://dx.doi.org/10.1097/icl.0b013e31827d546e.

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11

Efron, Nathan. "Are silicone hydrogel lenses safer?" Contact Lens and Anterior Eye 28, no. 4 (December 2005): 153–55. http://dx.doi.org/10.1016/j.clae.2005.10.004.

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12

Pesic, Snezana, Svetlana Jovanovic, Milos Mitrasevic, Biljana Vuletic, Milena Jovanovic, and Zorica Jovanovic. "The impact of silicone hydrogel contact lenses on the measurement of intraocular pressure using non-contact tonometry." Vojnosanitetski pregled 74, no. 8 (2017): 763–66. http://dx.doi.org/10.2298/vsp151102118p.

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Background/Aim. Measurement of intraocular pressure (IOP) over therapeutic silicone hydrogel soft contact lenses by a non-contact method of tonometry could be applied in opthalmologic practice but the results obtained are still controversial. The aim of this study was to evaluate the effect of spherically designed silicone hydrogel soft contact lenses and their power on values of IOP measured by using a noncontact tonometry method. Methods. We measured IOP with and without spherical silicone hydrogel soft contact lenses on 143 eyes of 80 subjects who did not have any ocular or systemic diseases. Results. The Wilcoxon statistical analysis test for ranking average values of IOP measured on 143 eyes over a spherical silicone hydrogel soft contact lenses showed significantly higher values compared to those measured with no contact lenses (15.81 ? 3.46 mm Hg vs 14.54 ? 3.19 mm Hg; respectively; Z = -5.224, p = 0.001). Refractive power analysis of the contact lenses of -9.00D to +6.00 D showed a significant difference of IOP in the range from 0.00D to -6.00D. Conclusion. Non-contact tonometry is not an accurate method of IOP measuring over spherical silicone hydrogel soft contact lenses which belong to therapeutic contact lenses.
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13

Su, Chen-Ying, Lung-Kun Yeh, Tzu-Wei Fan, Chi-Chun Lai, and Hsu-Wei Fang. "Albumin Acts as a Lubricant on the Surface of Hydrogel and Silicone Hydrogel Contact Lenses." Polymers 13, no. 13 (June 23, 2021): 2051. http://dx.doi.org/10.3390/polym13132051.

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Feeling comfortable is the greatest concern for contact lens wearers, and it has been suggested that in vivo comfort could be corresponded to the in vitro friction coefficient of contact lenses. How tear albumin could affect the friction coefficient of silicone hydrogel and hydrogel contact lenses was analyzed by sliding a lens against a quartz glass in normal and extremely high concentration of albumin solution. Albumin deposition testing and surface roughness analysis were also conducted. The results showed that the friction coefficient of tested contact lenses did not correspond to both the albumin deposition amount and surface roughness, but we proposed a model of how albumin might act as a lubricant on the surface of some hydrogel and silicone hydrogel contact lenses. In conclusion, albumin provided lubrication for silicone hydrogel contact lenses regardless of albumin concentrations, while albumin only acted as a lubricant for hydrogel contact under normal concentration.
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14

LOPOUR, P., Z. PLICHTA, Z. VOLFOVA, P. HRON, and P. VONDRACEK. "Silicone rubber-hydrogel composites as polymeric biomaterialsIV. Silicone matrix-hydrogel filler interaction and mechanical properties." Biomaterials 14, no. 14 (November 1993): 1051–55. http://dx.doi.org/10.1016/0142-9612(93)90204-f.

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15

Finelli, Anthony, Lori L. Burrows, Frank A. DiCosmo, Valerio DiTizio, Selva Sinnadurai, Dimitrios G. Oreopoulos, and Antoine E. Khoury. "Colonization-Resistant Antimicrobial-Coated Peritoneal Dialysis Catheters: Evaluation in a Newly Developed Rat Model of Persistent Pseudomonas Aeruginosa Peritonitis." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 22, no. 1 (January 2002): 27–31. http://dx.doi.org/10.1177/089686080202200105.

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Objective Development of a rat model of persistent peritonitis and evaluation of the ability of liposomal ciprofloxacin hydrogel-coated silicone to resist colonization. Design A newly developed model of persistent Pseudomonas aeruginosa peritonitis to compare the ability of liposomal ciprofloxacin hydrogel (LCH)-coated silicone versus plain silicone for resistance to bacterial colonization. Animals Male Sprague–Dawley rats. Results Inoculating the peritoneum of rats with 1 mL 0.5% agar containing 106 colony-forming units (cfu)/mL P. aeruginosa in the presence of a plain silicone coupon resulted in persistent peritonitis for at least 7 days. Plain silicone coupons in all 40 rats were colonized (median 2.54 × 103 cfu/cm2; range 5.0 × 101 – 1.0 × 106 cfu/cm2) and peritoneal washings were consistently culture-positive. In contrast, the LCH coupons removed after 7 days from the 40 test rats were sterile, as were the peritoneal washings, and there was no evidence of peritonitis. Blood cultures were negative in both groups. Conclusions Liposomal ciprofloxacin hydrogel-coated silicone resists colonization in this rat model of persistent P. aeruginosa peritonitis.
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16

Yasuda, Hirotsugu. "Biocompatibility of Nanofilm-Encapsulated Silicone and Silicone-Hydrogel Contact Lenses." Macromolecular Bioscience 6, no. 2 (February 10, 2006): 121–38. http://dx.doi.org/10.1002/mabi.200500153.

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17

Lee, Min-Jae, and A.-Young Sung. "Effect of Metal Oxide Nanoparticles on Silicone-Acrylate Copolymer Containing 1,3-Bis(3-aminopropyl)tetramethyldisiloxane." Journal of Nanoscience and Nanotechnology 20, no. 8 (August 1, 2020): 4753–60. http://dx.doi.org/10.1166/jnn.2020.17818.

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The silicone monomer used in this study contains acrylate group to prepare the hydrophilic polymer. For the polymerization, TMDS (1,3-Bis(3-aminopropyl)tetramethyldisiloxane) was added to the mixture containing synthesized silicone, DMA (N,N-dimethyl acrylamide), HEMA (2-Hydroxyethyl methacrylate), EGDMA (ethylene glycol dimethacrylate) and the initiator AIBN (azobisisobutyronitrile) with various concentrations. To make the functional hydrogel lens, metal oxide (Chromium oxide and Cobalt iron oxide) nanoparticles were used as additives. Using the polymer produced through the thermal polymerization process, the optical and physical characteristics of produced silicone hydrogel lenses were measured. The water content of sample was in the range of 63.70~69.08%, refractive index 1.3769~1.3880, contact angle 60.02~85.28°, and oxygen permeability (Dk) 24.79~37.92 × 10−11 (cm2/sec) (mlO2/mlmmHg). In case of the hydrogel sample with nanoparticles, the oxygen permeability value was increased with amount of nanoparticles. Silicone hydrogel monomer containing metal oxide nanoparticles were expected to be used usefully as a material for green tinted optical lens with high oxygen permeability.
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18

du Toit, Rènée, Judith Stern, and Debbie Sweeney. "Surfaces of silicone hydrogel contact lenses." International Contact Lens Clinic 27, no. 5 (September 2000): 191–92. http://dx.doi.org/10.1016/s0892-8967(02)00062-7.

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19

Vondráček, P., P. Lopour, and J. Šulc. "Silicone Rubber-Hydrogel Composites as Biomaterials." Journal of Bioactive and Compatible Polymers 6, no. 3 (July 1991): 256–62. http://dx.doi.org/10.1177/088391159100600305.

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Willcox, Mark D. P. "Microbial Adhesion to Silicone Hydrogel Lenses." Eye & Contact Lens: Science & Clinical Practice 39, no. 1 (January 2013): 60–65. http://dx.doi.org/10.1097/icl.0b013e318275e284.

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Sweeney, Deborah F. "Have Silicone Hydrogel Lenses Eliminated Hypoxia?" Eye & Contact Lens: Science & Clinical Practice 39, no. 1 (January 2013): 52–59. http://dx.doi.org/10.1097/icl.0b013e31827c7899.

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Lai, Yu-Chin, Ting-Chun Kuan, Hsiang-Ho Kung, Min-Tsong Yeh, Ching Wen Yang, and Tsung-Kao Hsu. "Novel water-processable silicone hydrogel lenses." Contact Lens and Anterior Eye 41 (June 2018): S61. http://dx.doi.org/10.1016/j.clae.2018.03.062.

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23

Maldonado-Codina, Carole, Philip Morgan, and Nathan Efron. "CHARACTERISATION OF HYDROGEL AND SILICONE HYDROGEL LENSES BY TOF-SIMS." Optometry and Vision Science 78, SUPPLEMENT (December 2001): 305. http://dx.doi.org/10.1097/00006324-200112001-00504.

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Maissa, Cécile, Michel Guillon, Nik Cockshott, Renee J. Garofalo, Jessie M. Lemp, and Joseph W. Boclair. "Contact Lens Lipid Spoliation of Hydrogel and Silicone Hydrogel Lenses." Optometry and Vision Science 91, no. 9 (September 2014): 1071–83. http://dx.doi.org/10.1097/opx.0000000000000341.

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Diec, Jennie, Daniel Tilia, and Varghese Thomas. "Comparison of Silicone Hydrogel and Hydrogel Daily Disposable Contact Lenses." Eye & Contact Lens: Science & Clinical Practice 44 (September 2018): S167—S172. http://dx.doi.org/10.1097/icl.0000000000000363.

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Ge, Qi, Zhe Chen, Jianxiang Cheng, Biao Zhang, Yuan-Fang Zhang, Honggeng Li, Xiangnan He, et al. "3D printing of highly stretchable hydrogel with diverse UV curable polymers." Science Advances 7, no. 2 (January 2021): eaba4261. http://dx.doi.org/10.1126/sciadv.aba4261.

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Hydrogel-polymer hybrids have been widely used for various applications such as biomedical devices and flexible electronics. However, the current technologies constrain the geometries of hydrogel-polymer hybrid to laminates consisting of hydrogel with silicone rubbers. This greatly limits functionality and performance of hydrogel-polymer–based devices and machines. Here, we report a simple yet versatile multimaterial 3D printing approach to fabricate complex hybrid 3D structures consisting of highly stretchable and high–water content acrylamide-PEGDA (AP) hydrogels covalently bonded with diverse UV curable polymers. The hybrid structures are printed on a self-built DLP-based multimaterial 3D printer. We realize covalent bonding between AP hydrogel and other polymers through incomplete polymerization of AP hydrogel initiated by the water-soluble photoinitiator TPO nanoparticles. We demonstrate a few applications taking advantage of this approach. The proposed approach paves a new way to realize multifunctional soft devices and machines by bonding hydrogel with other polymers in 3D forms.
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Kopeć, Kamil, Michał Żuk, and Tomasz Ciach. "HYDROGEL ANTIBACTERIAL COATING FOR SILICONE MEDICAL DEVICES." Progress on Chemistry and Application of Chitin and its Derivatives 26 (September 30, 2021): 135–47. http://dx.doi.org/10.15259/pcacd.26.012.

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Effective antibacterial coatings are in demand in medicine, especially for urological medical devices such as catheters and stents. We propose the production method of an antibacterial hydrogel coating on polydimethylsiloxane (PDMS, silicone), a popular surface for medical materials. The coating process consists of the following steps: PDMS surface activation (introduction of hydroxyl groups), silanisation (introduction of amine groups) and application of chitosan/alginate hydrogel with the addition of lysozyme as an antibacterial agent using the layer-by-layer method. We investigated the effect of polyion concentration on the coating mass, swelling ratio and stability. We analysed the adsorption of Micrococcus luteus, Escherichia coli and Proteus rettgeri on a PDMS surface using confocal laser scanning microscopy. The chitosan/alginate hydrogel coating with immobilised lysozyme protected the PDMS surface against adhesion for all three tested bacterial strains.
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Kim, Young-Ah, Jin-Oh Jeong, and Jong-Seok Park. "Preparation and Characterization of Ionic Conductive Poly(acrylic Acid)-Based Silicone Hydrogels for Smart Drug Delivery System." Polymers 13, no. 3 (January 27, 2021): 406. http://dx.doi.org/10.3390/polym13030406.

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In this study, we developed a smart drug delivery system that can efficiently deliver the required amounts of drugs using the excellent ion conductivity of poly(acrylic acid) (PAA) and an electrical stimulus. As a result of its having carboxyl groups, PAA hydrogel can be used in drug delivery patches to release drugs by ionic conductivity. However, PAA hydrogel has low durability and poor mechanical properties. The carboxyl group of PAA was combined with a siloxane group of silicone using electron-beam irradiation to easily form a crosslinked structure. The PAA–silicone hydrogel has excellent mechanical properties. Specifically, the tensile strength increased more than 3.5 times. In addition, we observed its cell compatibility using fluorescence staining and CCK-8 assays and found good cell viability. Finally, it was possible to control the drug delivery rate efficiently using the voltage applied to the ion-conductive hydrogel. As the voltage was increased to 3, 5, and 7 V, the amount of drug released was 53, 88, and 96%, respectively. These excellent properties of the PAA–silicone hydrogel can be used not only for whitening or anti-wrinkling cosmetics but also in medical drug-delivery systems.
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Wu, Shengnan, Chanhong Chung, and Younghwan Kwon. "Synthesis and Characterization of Monosaccharide-Containing 2-(α-D-mannopyranosyloxy)Ethyl Methacrylate as a Surface Modifier for Hydrogels." Journal of Nanoscience and Nanotechnology 20, no. 9 (September 1, 2020): 5609–13. http://dx.doi.org/10.1166/jnn.2020.17645.

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We introduce a hydrophilic monosaccharide-containing 2-(α-D-mannopyranosyloxy)ethyl methacrylate (ManEMA) in this study to achieve more extended and comfortable wear silicone hydrogel contact lenses by increasing water content. Molecular structure of ManEMA contains a monosaccharide moiety with four hydroxyl groups, which provide a strong interaction with water. Therefore, the ManEMA-containing hydrogels are expected to have high water content. The structure of synthesized ManEMA is confirmed by 1H and 13C NMR spectroscopy. Contact lenses containing silicone polymers are coated with a monosaccharide-containingManEMA monomer with the help of plasma treatment and the use of 3-(trimethoxylsilyl)propyl methacrylate to provide an increased hydrophilicity. The feasibility of ManEMA as a surface modifier of silicone lenses is investigated in terms of water content and surface energy.
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MUTALIB, H. A., LIM, and Y. V. "Ocular Comfort Assessment in Hydrogel and Silicone Hydrogel Contact Lens Wearers." Jurnal Sains Kesihatan Malaysia 16, no. 02 (January 15, 2018): 65–69. http://dx.doi.org/10.17576/jskm-2018-1602-08.

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Bonanno, Joseph A., Christopher Clark, John Pruitt, and Larry Alvord. "Tear Oxygen Under Hydrogel and Silicone Hydrogel Contact Lenses in Humans." Optometry and Vision Science 86, no. 8 (August 2009): E936—E942. http://dx.doi.org/10.1097/opx.0b013e3181b2f582.

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Pucker, Andrew D., Mirunalni Thangavelu, and Jason J. Nichols. "In Vitro Lipid Deposition on Hydrogel and Silicone Hydrogel Contact Lenses." Investigative Opthalmology & Visual Science 51, no. 12 (December 1, 2010): 6334. http://dx.doi.org/10.1167/iovs.10-5836.

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Jang, Seung Won, Eui Sang Chung, and Tae Young Chung. "Comparison of Hydrogel and Silicone Hydrogel Bandage Contact Lens after LASEK." Journal of the Korean Ophthalmological Society 48, no. 10 (2007): 1323. http://dx.doi.org/10.3341/jkos.2007.48.10.1323.

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Guillon, Michel. "Are Silicone Hydrogel Contact Lenses More Comfortable Than Hydrogel Contact Lenses?" Eye & Contact Lens: Science & Clinical Practice 39, no. 1 (January 2013): 85–91. http://dx.doi.org/10.1097/icl.0b013e31827cb99f.

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Mousavi, Maryam, Izabela Garaszczuk, Dorota Szczesna-Iskander, James Wolffsohn, D. Robert Iskander, and Maryam Mousavi. "Relative performance of well fitted hydrogel and silicone hydrogel contact lenses." Contact Lens and Anterior Eye 41 (June 2018): S78. http://dx.doi.org/10.1016/j.clae.2018.03.117.

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Dumbleton, Kathy. "Adverse events with silicone hydrogel continuous wear." Contact Lens and Anterior Eye 25, no. 3 (September 2002): 137–46. http://dx.doi.org/10.1016/s1367-0484(02)00009-7.

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Peng, Cheng-Chun, and Anuj Chauhan. "Ion transport in silicone hydrogel contact lenses." Journal of Membrane Science 399-400 (May 2012): 95–105. http://dx.doi.org/10.1016/j.memsci.2012.01.039.

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Scantling, Ashley, William Edmondson, and Earlena McKee. "Masking Astigmatism With Silicone Hydrogel Contact Lenses." Optometry - Journal of the American Optometric Association 80, no. 6 (June 2009): 293. http://dx.doi.org/10.1016/j.optm.2009.04.016.

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Willcox, Mark D. P. "Solutions for Care of Silicone Hydrogel Lenses." Eye & Contact Lens: Science & Clinical Practice 39, no. 1 (January 2013): 23–27. http://dx.doi.org/10.1097/icl.0b013e318275e0d9.

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Carnt, Nicole, and Fiona Stapleton. "Silicone Hydrogel Lens–Solution Interaction and Inflammation." Eye & Contact Lens: Science & Clinical Practice 39, no. 1 (January 2013): 36–40. http://dx.doi.org/10.1097/icl.0b013e31827d4ba1.

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41

Mann, Aisling, Fiona Lydon, Virginia Saez-Martinez, and Brian Tighe. "Protein permeation through silicone hydrogel contact lenses." Contact Lens and Anterior Eye 42, no. 6 (December 2019): e27-e28. http://dx.doi.org/10.1016/j.clae.2019.10.092.

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42

Sulley, Anna, and Kathy Dumbleton. "Silicone hydrogel daily disposable benefits: The evidence." Contact Lens and Anterior Eye 43, no. 3 (June 2020): 298–307. http://dx.doi.org/10.1016/j.clae.2020.02.001.

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43

Cifková, I., P. Lopour, P. Vondráček, and F. Jelínek. "Silicone rubber-hydrogel composites as polymeric biomaterials." Biomaterials 11, no. 6 (August 1990): 393–96. http://dx.doi.org/10.1016/0142-9612(90)90093-6.

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44

Lopour, P., P. Vondráček, V. Janatová, J. Šulc, and J. Vacik. "Silicone rubber-hydrogel composites as polymeric biomaterials." Biomaterials 11, no. 6 (August 1990): 397–402. http://dx.doi.org/10.1016/0142-9612(90)90094-7.

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45

Lopour, P., and V. Janatová. "Silicone rubber-hydrogel composites as polymeric biomaterials." Biomaterials 16, no. 8 (January 1995): 633–40. http://dx.doi.org/10.1016/0142-9612(95)93861-7.

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46

Kim, Jeong-Mee. "Silicone Hydrogel Contact Lens Wear and Dryness." Journal of Korean Ophthalmic Optics Society 26, no. 3 (September 30, 2021): 199–205. http://dx.doi.org/10.14479/jkoos.2021.26.3.199.

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47

Tran, Nguyen-Phuong-Dung, and Ming-Chien Yang. "The Ophthalmic Performance of Hydrogel Contact Lenses Loaded with Silicone Nanoparticles." Polymers 12, no. 5 (May 14, 2020): 1128. http://dx.doi.org/10.3390/polym12051128.

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Abstract:
In this study, silicone nanoparticles (SiNPs) were prepared from polydimethylsiloxane (PDMS) and tetraethyl orthosilicate (TEOS) via the sol-gel process. The resultant SiNPs were characterized by dynamic light scattering (DLS), transmission electron microscope (TEM), and scanning electron microscope (SEM). These SiNPs were then blended with 2-hydroxyethylmethacrylate (HEMA) and 1-vinyl-2-pyrrolidinone (NVP) before polymerizing into hydrogel contact lenses. All hydrogels were subject to characterization, including equilibrium water content (EWC), contact angle, and oxygen permeability (Dk). The average diameter of SiNPs was 330 nm. The results indicated that, with the increase of SiNPs content, the oxygen permeability increased, while the EWC was affected insignificantly. The maximum oxygen permeability attained was 71 barrer for HEMA-NVP lens containing 1.2 wt% of SiNPs with an EWC of 73%. These results demonstrate that by loading a small amount of SiNPs, the Dk of conventional hydrogel lenses can be improved greatly. This approach would be a new method to produce oxygen-permeable contact lenses.
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48

Si, Liqi, Xiaowen Zheng, Jun Nie, Ruixue Yin, Yujie Hua, and Xiaoqun Zhu. "Silicone-based tough hydrogels with high resilience, fast self-recovery, and self-healing properties." Chemical Communications 52, no. 54 (2016): 8365–68. http://dx.doi.org/10.1039/c6cc02665f.

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A dual-component polymer hydrogel was prepared by one-pot, tandem polymerization. The concentration of monomer could be tuned freely due to the good water solubility of both monomers. The prepared hydrogels exhibited toughness, high resilience, fast self-recovery, and self-healing properties.
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49

Arion, Henri-Gilbert. "Hydrogel for Mammary Prostheses." American Journal of Cosmetic Surgery 14, no. 1 (March 1997): 13–14. http://dx.doi.org/10.1177/074880689701400104.

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Since the withdrawal of silicone-gel implants from the market by the Federal Drug Administration in 1992 except for research protocol, there has been continued research to find a substitute filler which is nontoxic and biodegradable. The gel of carboxymethylcellulose has been found to have a mild local tissue reaction which is short in duration, and the substance apparently completely degrades without toxicity. Early research into carboxymethylcellulose is described.
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50

Skrypnyk, Rimma, and Olga Selezneva. "Compliance as an Integral Part of the Dry Eye Syndrome Prevention Using Silicone Hydrogel Contact Lenses." Galician Medical Journal 23, no. 4 (November 1, 2016): 201647. http://dx.doi.org/10.21802/gmj.2016.4.7.

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The probability of dry eye syndrome (DES) in the patients using the Silicone-Hydrogel Contact Lenses is examined in many researches. Therefore, adhering to clinical recommendations is an important factor for DES prevention. The urgent issue is also a comprehensive assessment of functional parameters as pathogenetic base of DES.The objective of the research was tostudy DES development depending on compliance of silicone hydrogel contact lenses users.Matherials and methods. 97 patients (194 eyes) were included into the research. They formed 2 groups: group I with incomplete compliance (36 persons) and group II with complete compliance (61 persons). All the patients underwent the Norn’s test, Schirmer’s test, Jones test, tear film stability was defined. The probability of the dry eye syndrome development due to the subjective signs was also analysed.Results. The reliable decrease in the total (р<0.05) and basale lacrimation (р<0.05) indexes, the increase in osmolarity (р<0.05) and decrease in tear film stability (р<0.05) were detected in the patients who did not follow the clinical guidance during the Silicone-Hydrogel Contact Lenses wearing. In the same group the higher risk of dry eye syndrome development was verified (р<0.05).Conclusion. Compliance disorder in the patients using Silicone-Hydrogel Contact Lenses was found to induce the reliable decrease in total and basale lacrimation, increase in osmolarity and tear stability disorder. All of this factors increase the risk of dry eye syndrome.
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