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Dissertations / Theses on the topic 'Side effects'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Josephs, M. B. "Functional programming with side-effects." Thesis, University of Oxford, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.375263.

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2

Cyphers, Benjamin. "Side Effects of 0.01% Atropine." The Ohio State University, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=osu161701167574429.

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3

Kelly, Vincent. "β–alanine: performance effects, usage and side effects". Thesis, University of Queensland, 2017. https://eprints.qut.edu.au/180848/1/43068631.pdf.

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β-alanine is a relatively new ergogenic aid and a number of questions relating to its effectiveness in enhancing high intensity exercise performance remain to be addressed. The five studies described in this thesis examined the influence of β-alanine supplementation and high intensity training on exercise capacity and considered factors that potentiallyinfluence dosage compliance and side effects – factors that may impact on the ergogenic value of β-alanine supplementation.Study 1 examined the efficacy of β-alanine supplementation in conjunction with repeated sprint and sprint interval trainin

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4

Colagiuri, Ben. "Expectancies in Double-Blind Randomised Placebo-Controlled Trials and Placebo-Induced Side Effects." Thesis, The University of Sydney, 2009. http://hdl.handle.net/2123/8595.

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The majority of research on the placebo effect has focused on beneficial effects in patients or participants told to expect an active treatment, but who are actually given a placebo. Two important and relatively understudied aspects of the placebo effect are the extent to which expectancies influence outcomes in double-blind randomised placebo-controlled trials (RCTs) and whether the placebo effect contributes to treatment side effects. The current project investigated these two issues in both clinical and experimental settings. The first study involved reanalysing a double-blind RCT of naltre

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5

Mischkowski, Dominik. "The Social Side Effects of Acetaminophen." The Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1438081282.

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6

Chu, Yu-Hsuan. "Custom Fluorophores for Investigating the Cellular Uptake Mechanisms and Side-Effects of Pharmaceuticals." PDXScholar, 2015. http://pdxscholar.library.pdx.edu/open_access_etds/2343.

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There is a significant current need to elucidate the molecular mechanisms of the side-effects caused by widely-used pharmaceuticals. Examples include the acute nephrotoxicity and irreversible ototoxicity promoted by the cationic drugs gentamicin and cisplatin. Gentamicin is an aminoglycoside antibiotic used for the prevention and treatment of life-threatening gram-negative bacterial infections, such as tuberculosis and meningitis. Cisplatin is used to treat a broad spectrum of cancers including head and neck, ovarian, cervical, stomach, bladder, sarcoma, lymphoma, testicular cancer and others.

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7

Ahmed, Al-Obeidi Fahad. "Design, synthesis, conformation and biological activities of cyclic alpha-melanotropin and related compounds." Diss., The University of Arizona, 1988. http://hdl.handle.net/10150/184445.

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This research initiated an investigation of the structural relationships between melanocyte stimulating hormone (α-MSH) and its melanin dispersion on lizard (Anolis carolinensis) and frog (Rana pipiens) skins bioassays as representing models for mammalian and amphibian melanocytes, respectively. From previous extensive structure-activity relationships of α -MSH together with the theoretical modeling we were able to design a group of linear and cyclic peptides related to "4-10" fragment analogues of α -MSH. The solid phase synthesis of α -MSH and its related analogues using the p-methyl-benzhyd

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8

Clark, Brodie. "Side Effects May Depend on the Framing of a Warning: But Does this Framing Effect Depend on Absolute Risk?" Thesis, Faculty of Science, School of Psychology, 2019. https://hdl.handle.net/2123/28535.

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Side effect warnings contribute directly to the burden of side effects. This occurs via the nocebo effect whereby negative outcomes are shaped by features of the treatment context, beyond the direct actions of the active treatment. Some studies have found that positive framing of warnings – stating the proportion of people who will not experience the side effect – reduces side effects compared to the more common-place negative framing – stating the proportion who will experience the side effect. However, findings have been mixed. It appears that the absolute risk ascribed to the side effect ma

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9

McGee, Michael K. "Assessing Negative Side Effects in Virtual Environments." Thesis, Virginia Tech, 1998. http://hdl.handle.net/10919/35766.

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Virtual environment (VE) systems have been touted as exciting new technologies with many varied applications. Today VEs are used in telerobotics, training, simulation, medicine, architecture, and entertainment. The future use of VEs seems limited only by the creativity of its designers. However, as with any developing technology, some difficulties need to be overcome. Certain users of VEs experience negative side effects from being immersed into the graphically rendered virtual worlds. Some side effects that have been observed include: disorientation, headaches, and difficulties with visi

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10

Rundqvist, Konrad. "Side effects of level dependent hearing protectors." Thesis, Luleå tekniska universitet, Institutionen för ekonomi, teknik och samhälle, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-82150.

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Hearing protectors are used in noisy environments to attenuate damaging soundlevels. Problems are reported to arise from using hearing protectors, since usefulsounds also are attenuated. Not only are sound levels attenuated, but other humanabilities are affected by hearing protectors, such as the ability to identify and localizesounds. Manufacturers of hearing protectors also develop level-dependent hearingprotectors that are supposed to create a better listening experience for the user thandoes passive hearing protectors. This thesis investigates how the ability to identifysound is affected b

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11

Chumbley, Gillian Mary. "Patients' evaluation of patient controlled analgesia after surgery." Thesis, St George's, University of London, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249438.

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12

Benson, John Arthur. "Patients' perceptions about blood pressure medication and their relationship to medicine taking." Thesis, King's College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248397.

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13

Ospina, Arango Juan David. "Predictive models for side effects following radiotherapy for prostate cancer." Thesis, Rennes 1, 2014. http://www.theses.fr/2014REN1S046/document.

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La radiothérapie externe (EBRT en anglais pour External Beam Radiotherapy) est l'un des traitements référence du cancer de prostate. Les objectifs de la radiothérapie sont, premièrement, de délivrer une haute dose de radiations dans la cible tumorale (prostate et vésicules séminales) afin d'assurer un contrôle local de la maladie et, deuxièmement, d'épargner les organes à risque voisins (principalement le rectum et la vessie) afin de limiter les effets secondaires. Des modèles de probabilité de complication des tissus sains (NTCP en anglais pour Normal Tissue Complication Probability) sont néc

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14

Nilsson, Greger. "Cardiovascular Side Effects of Radiotherapy in Breast Cancer." Doctoral thesis, Uppsala universitet, Enheten för onkologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-179811.

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The aim of the thesis was to study cardiovascular side effects of radiotherapy (RT) in breast cancer (BC). In a study base of 25,171 women with BC diagnosed 1970-2000, we found a statistically significant 12% increase of stroke, compared to the stroke incidence in the background population. A case-control study of 282 cases with BC followed by a stroke and 1:1 matched controls with BC but not stroke was performed. In women irradiated to internal mammary chain (IMC) and supraclavicular lymph nodes (SCL) vs. a pooled group of women not irradiated or irradiated to targets other than IMC and SCL,

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15

Weitoft, Tomas. "Intra-articular Glucocorticoid Treatment : Efficacy and Side Effects." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5897.

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16

Heller, M. K. "The role of medication beliefs in side effects." Thesis, University College London (University of London), 2017. http://discovery.ucl.ac.uk/1563528/.

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The experience (or mere anticipation) of side effects influences patients’ beliefs about specific treatment and pharmaceuticals in general. In this thesis I postulate that beliefs about medication may also contribute to side effect reporting. Five studies were conducted to test this hypothesis and to explore putative underlying mechanisms. The majority of studies examining the relationship between medication beliefs and side effect reporting are cross-sectional, precluding inferences about the direction of the relationship. I present evidence from a prospective study showing that baseline medi

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17

Isherwood, Ruth Jayne. "Opioid-related side-effects and opioid-induced hyperalgesia." Thesis, University of Glasgow, 2015. http://theses.gla.ac.uk/6598/.

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Introduction: Opioids are widely used for the management of cancer and chronic non-cancer pain and the maintenance management of patients with a history of substance misuse. Increasingly the use of opioids is being scrutinised as patients are prescribed opioids for longer periods and the long-term effects of the opioids becomes clinically more relevant and evident. Our work has explored the prevalence of opioid-related side-effects in patients who are prescribed opioids and explored the clinically relevant phenomenon of opioid-induced hyperalgesia. . Methods: Patients were recruited who were p

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18

Husman, Stephen H. "Side-dress Temik® Effects on Lint Yields." College of Agriculture, University of Arizona (Tucson, AZ), 1998. http://hdl.handle.net/10150/210391.

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Temik 15G was side-dressed at a rate of 7 lb./acre and 14 lb./acre and compared to an untreated check in 4 experiments in 1996 and 1997 in Buckeye, Az. Treatments were made just prior to early bloom. Lygus counts were taken using a sweep net on weekly intervals for four to six weeks post application. A net positive return on investment (ROI) ranging from $34.79/acre to $48.19/acre was realized in three of the four experiments with the seven lb./acre rate. One experiment resulted in a net economic loss of $24.84. A net positive ROI was experienced in two of the four experiments ranging from $23

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19

Husman, S. H., and B. Deeter. "Side-Dress Temik® Effects on Lint Yields." College of Agriculture, University of Arizona (Tucson, AZ), 1997. http://hdl.handle.net/10150/211107.

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Temik 15G was side -dressed at a rate of 7 lb./acre and 14 lb./acre and compared to an untreated check in two experiments in Buckeye, Az.. Treatments were made prior to the second in- season irrigation (June 3 and June 5) which was just prior to early bloom. Lygus counts were taken using a sweep net on weekly intervals for six weeks post application. The first experiment resulted in a significant increase of 123 lb. and 1241b. lint in both the 7 and 14 lb. rate treatment respectively over the untreated check. The second experiment resulted in a significant 102 lb. lint increase for the 7 lb. t

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20

Saint-Clarke, Gwendolyn E. "Chemotherapy Side Effects at Home: A Nursing Impact." NSUWorks, 2017. https://nsuworks.nova.edu/hpd_con_stuetd/49.

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Background: Approximately 32% of all lymphoma patients experience immunocompromised severe avoidable side effects of nadir at home after discharge postchemotherapy. The certified oncology nurses employed at a large metropolitan hospital in Atlanta, Georgia, lack standardized discharge guidelines that include regulatory organizations’ recommendations to assist patients/families with at-home self-management of the avoidable side effects. Purpose: The purpose of this quality improvement project was to utilize the institution’s existing postchemotherapy discharge protocol to assess certified oncol

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21

江卓庭 and Cheuk-ting Kong. "Chloramphenicol-induced toxicity on haemopoiesis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1998. http://hub.hku.hk/bib/B3122099X.

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22

Gyenes, Gábor. "Cardiac side-effects of adjuvant radiotherapy for early breast cancer /." [Budapest] ; Stockholm, 1997. http://diss.kib.ki.se/1997/963-9106-04-6.

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23

Gharanei, A. M. "Investigation into the cardiotoxic effects of doxorubicin and strategies for cardioprotection." Thesis, Coventry University, 2013. http://curve.coventry.ac.uk/open/items/ad712004-828e-4d9a-8ddb-17951146d414/1.

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Doxorubicin is one of the most effective anti-cancer agents; however its use is associated with adverse cardiac effects, including cardiomyopathy and progressive heart failure. Mitochondrial function and integrity are crucial for cellular processes in general and play an important role during diseased development. These characteristics of the mitochondria make them the prime target for treatments for majority of diseases and in particular of the cardiovascular system. The mitochondria are also considered to play an integral role in the manifestation of the cardiotoxic effects of compounds such

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24

Riley, Philip. "The prevention of oral side effects of cancer treatment." Thesis, University of Manchester, 2017. https://www.research.manchester.ac.uk/portal/en/theses/the-prevention-of-oral-side-effects-of-cancer-treatment(dee3fd53-35f7-448a-8572-591c1bf9c874).html.

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Background: Treatments for cancer can cause a range of oral side effects which can compromise patients' quality of life and even their chances of survival. The evidence for the prevention of some of these side-effects, primarily oral mucositis and salivary gland dysfunction, is often scarce or conflicting. Such evidence is needed to support the recommendations given in clinical guidelines. Aims: (i) To assess the effects of interventions for preventing oral mucositis in patients with cancer who are receiving treatment; (ii) To assess the effects of pharmacological interventions for the prevent

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25

Andersson, Anne. "Long-term side effects after treatment of Hodgkin's lymphoma." Doctoral thesis, Umeå universitet, Onkologi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-43287.

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Background Long-term side effects associated with the treatment of Hodgkin’s lymphoma (HL) have frequently been reported during the last decades. Studies have shown increased mortality in HL survivors. Following Hodgkin’s lymphoma, second malignancies (SM) and cardiovascular disease (CVD) are the most common causes of death in individuals treated for HL. This study investigates the incidence of side effects such as SM, CVD and infections in a cohort diagnosed with HL in Sweden between 1965 and 1995. In addition, this study identifies covariate risk factors for late side effects in order to dev

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26

Caliari, De Lima Lucas. "Construction Effects on the Side Shear of Drilled Shafts." Scholar Commons, 2017. http://scholarcommons.usf.edu/etd/7004.

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Design methods for side shear of drilled shafts, including the resistance factors that should be applied, do not account for any specific construction procedure. Instead, design often relies on analysis of case studies which include all construction methods used in each geomaterial type (e.g. clays, sands and rocks), or on parametric analysis. Nonetheless, literature suggests that different construction procedures result in varying side shear. This research investigated 2 types of construction: (1) slurry stabilization in sandy soils using bentonite and polymer products tha

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27

Buijs, Ciska. "Long-term side effects of adjuvant breast cancer treatment." [S.l. : Groningen : s.n. ; University Library of Groningen] [Host], 2008. http://irs.ub.rug.nl/ppn/306087480.

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28

Humphries, Courtney (Courtney Elizabeth). "Side effects : the new age of AIDS in America." Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/39435.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Humanities, Program in Writing and Humanistic Studies, 2004.<br>Vita.<br>Includes bibliographical references (leaves 29-32).<br>When the cocktail of AIDS drugs called highly active antiretroviral therapy (HAART) was introduced in 1997, it radically changed the picture of HIV and AIDS in the U.S. Deaths from AIDS plummeted by two-thirds. Now, far fewer people are progressing along the once-inevitable path to illness and death. The impact of new therapy has been both dramatic and double-edged: it has spared tens of thousands from dea

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29

ASTESANA, VALENTINA. "Alternative strategies to overcome Cisplatin side effects and resistance." Doctoral thesis, Università degli studi di Pavia, 2019. http://hdl.handle.net/11571/1231866.

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Cisplatin is one of the most effective chemotherapeutic agents used in the treatment of many type of tumours including non-small cell lung cancer, ovarian, testicular, glioblastoma, neuroblastoma and others. Cisplatin is able to form bonds with the N7 atom on guanine and adenine bases and when this damage is not repaired, DNA replication and transcription were stopped, inducing death of the cells. Despite the clinical benefit provided by Cisplatin many patients undergo phenomena of resistance and toxicity (especially ototoxicity, nephrotoxicity and neurotoxicity). Cisplatin resistance is gener

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30

Ewen, C. "The effects of radiation and chemotherapy on late responding tissues." Thesis, University of Manchester, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.383217.

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31

O'Donovan, Bernadine. "'Beyond the desired effect' : patients' experiences in identifying and managing side effects from medicines." Thesis, University of Kent, 2017. https://kar.kent.ac.uk/66995/.

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Side effects from medicines can have considerable negative impact on peoples' daily lives. As a result of an aging UK population and attendant multi-morbidity, an increasing number of medicines are being prescribed for patients, leading to increased risk of unintended side effects. The aim of this study was to explore experiences and opinions of patients and the public in identifying and managing side effects from medicines. It also sought to develop a novel causality scale for use by patients to assess suspected side effects. A mixed methods approach with four phases was selected. In Phase On

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32

Patel, Bhavesh Kantilal. "Stereospecific bioanalysis of ibuprofen and flurbiprofen : application to dispositional studies in humans." Thesis, King's College London (University of London), 2000. https://kclpure.kcl.ac.uk/portal/en/theses/stereospecific-bioanalysis-of-ibuprofen-and-flurbiprofen--application-to-dispositional-studies-in-humans(4ce11f77-500a-448e-b70d-34ae194fb662).html.

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33

Zahir, Sheba Adam. "Evaluating the efficacy of DNA repair biomarkers to assess human cell response to chemotherapy using imaging flow cytometry." Thesis, Brunel University, 2013. http://bura.brunel.ac.uk/handle/2438/7768.

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Chemotherapy and radiotherapy are widely accepted as common forms of treatment for cancers. The majority of cancer patients receive chemotherapy alone or in combination with radiotherapy. Most chemotherapeutic drugs cause DNA damage to the rapidly dividing cancer cells but normal cells are also damaged in the process. Therefore DNA repair levels in tumour and normal cells may determine the success of the treatment. The aim of this work was to evaluate the use of DNA repair biomarkers for assessing responses to chemotherapeutic drugs. The novel technique of imaging flow cytometry was employed t

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34

Binks, Stephen Peter. "Absorption, toxicity and deposition of transition metal based pharmaceuticals following oral administration." Thesis, University of Surrey, 1988. http://epubs.surrey.ac.uk/847165/.

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The aim of this dissertation was to study the absorption, and subsequent toxic side effects of transition metal based pharmaceuticals following oral administration to rats. Administration of cisplatin (30mg/kg), carboplatin (37mg/kg) and iproplatin (42mg/kg) by oral gavage resulted in their rapid absorption so that respective peak blood levels of 2.63mug platinum/ml, 1.48mug platinum/ml and 3.13mug platinum/ml were achieved within 2-4 hours. Approximately 3-4% of the dose was excreted in the urine, but the major route of elimination was the faeces (>75%). This indicated that although rapid, ab

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35

Martinez, Ramon D. "Purification and characterization of Clostridium sordellii toxins HT and LT and comparison to toxins A and B of Clostridium difficile." Diss., Virginia Polytechnic Institute and State University, 1989. http://hdl.handle.net/10919/54238.

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Clostridium sordellii cause gas gangrene in man and animals, and more recently it has been implicated as a causal agent of diarrhea and enterotoxemia in domestic animals. This organism was once believed to cause pseudomembranous colitis (PMC) in humans, however, Clostridium difficile, not C. sordellii, was found to be the causative agent of this disease. It is now known that C. difficile produces two toxins, designated A and B, that are implicated in the pathogenesis of the disease. C. sordellii produces two toxins, designated HT (Hemorrhagic Toxin) and LT (Lethal Toxin), that are similar to t

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36

Brown, Mary Catherine. "The impact of side effects on travellers' compliance with antimalarials." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ29663.pdf.

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37

Svensson, Staffan. "Medication adherence, side effects and patient-physician interaction in hypertension /." Göteborg : Department of Clinical Pharmacology, Institute of Internal Medicine, The Sahlgrenska Academy at Göteborg University, 2006. http://hdl.handle.net/2077/635.

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Brown, Mary Catherine 1964. "The impact of side effects on travellers' compliance with antimalarials /." Thesis, McGill University, 1997. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=35308.

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The association between side effects to antimalarial chemoprophylaxis and noncompliance was assessed in travellers visiting five pre-travel clinics in the greater Montreal area between February and August 1996. Participants completed pre and post-travel questionnaires to ascertain frequency and severity of side effects and compliance with malaria chemoprophylaxis. A participation rate of 83% was achieved. Of 157 travellers prescribed mefloquine and 132 travellers prescribed chloroquine, proportions experiencing symptoms or side effects were high (7% and 83%, respectively), but not statisticall

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39

Lundkvist, Erik. "Side effects of being tired : burnout among Swedish sport coaches." Doctoral thesis, Umeå universitet, Institutionen för psykologi, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-98056.

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Burnout is a psychological concept that have got much attention since it was first defined in the middle of the 1970s. Although the definition of burnout differ there is consensus about exhaustion as the most important part of the concept. Burnout have also been in focus in sport psychology research. Mostly athletes have been studied but interest the coach profession have also been of interest. Research on coach burnout have mostly been directed towards demographic variables, organizational issues, behaviors and emotions and more holistic perspectives covering larger models or theories. The ai

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40

Fraser, Douglas (Douglas H. ). "Triptycene side unit effects on compressive yield strength in polycarbonates." Thesis, Massachusetts Institute of Technology, 2006. http://hdl.handle.net/1721.1/35071.

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Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2006.<br>Includes bibliographical references (leaf 25).<br>Polycarbonates have long been studied for their excellent mechanical toughness. Adding side units to polycarbonate could increase physical properties of the polymer. The role of triptycene in polycarbonate was studied by adding a low concentration of triptycene-containing polymer chains, and using compression testing. The triptycene polycarbonate was a blend created from two separate products. Differential Scanning Calorimetry was used to

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Kallam, Kalyani. "Side chain decoration of anthocyanins : mechanisms and effects on functionality." Thesis, University of East Anglia, 2012. https://ueaeprints.uea.ac.uk/42384/.

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Anthocyanins are plant pigments offering a range of colours to fruits and flowers. Many properties of anthocyanins are influenced by the degree and type of side chain modifications. Though much is known about the biosynthesis of anthocyanins and the enzymes involved in side-chain decoration, there is limited understanding of the structural features of anthocyanin acyltransferases that determine their substrate preference. Anthocyanin acyltransferases belong to the BAHD family of enzymes and are involved in acylation. Through mutagenesis I showed that an arginine positioned close to motif-1 in

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42

Franco, Nuno Filipe Barradas. "Business models for airport management and development: air-side effects." Master's thesis, Universidade da Beira Interior, 2009. http://hdl.handle.net/10400.6/2047.

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The civil aviation has always faced demanding challenges. One of the challenges of our days is the massification of its main product: air travel. The increased mobility in our society determines that, different airports, in a geographic area, compete for the same market. The airlines, their main clients, face a particularly difficult situation, also dealing with though competition and high operational costs, adding to this, the oil prices escalade may have restarted, thus guessing a difficult picture for the airlines in a near future and increased pressure over the airports’ taxation policies

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Brookshire, Stephen William. "A Novel Bifunctional Opioid That Lacks Traditional Opioid Side Effects." Thesis, The University of Arizona, 2012. http://hdl.handle.net/10150/243897.

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Prescription opioids, such as morphine, remain an important part in the management of pain. However, their clinical utility can be limited by side effects such as constipation, nausea, and high risk of addiction. Additionally, abuse of prescription opioids has been on the rise in recent years. Therefore, it is necessary to develop effective analgesics that lack the rewarding properties of currently used opioids. The neurokinin-1 receptor (NK-1) and its endogenous ligand, Substance P (SP), have been implicated in the control of nausea and vomiting, as well as mediating the rewarding effects of

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44

Padayachee, Vaneshree. "Awareness regarding non-steroidal anti-inflammatory drug-related side effects in Johannesburg, South Africa." University of Western Cape, 2021. http://hdl.handle.net/11394/8370.

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>Magister Scientiae - MSc<br>Non-steroidal anti-inflammatory drugs (NSAIDs) are amongst the most commonly used medications globally, as they are highly effective and easily accessible. The NSAIDs are indicated for mild to moderate pain management. The increasing incidence of NSAID related side effects and hospitalisations has raised a concern about these medications’ safety. The prevalence of these side effects has drastic consequences to a challenged South Africanpublic healthcare system. The implications of not treating severe, potentially preventable upper gastrointestinal complications att

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45

Powers, Tiffany M. "Expression patterns of cyclin D1, D2, and D3 in the first three cell cycles in preimplantation embryo development." Virtual Press, 2004. http://liblink.bsu.edu/uhtbin/catkey/1306857.

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Cell-cycle progression in mammalian cells is coordinated by a series of control points. The D-type cyclins are a family of key cell cycle regulators that are controlled largely by mitogens and their association with and activation of cdk 4 and 6 at the G1 phase of the cell cycle. This study seeks to first analyze cyclins D1, D2, and D3 expression patterns in preimplantation mouse embryos using in vivo studies and then analyze the effects of Dilantin on the cyclin D1 expression pattern in cultured embryos. Antibody staining against cyclin D1, D2, and D3 via indirect immunofluorescence using a Z

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46

Petley, Anne M. "Nicotinamide : implications for the prevention and treatment of Type I diabetes." Thesis, University of Southampton, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.295712.

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Олещенко, Галина Павлівна, Галина Павловна Олещенко, Halyna Pavlivna Oleshchenko та К. П. Гніденко. "Особливості побічних реакцій на протитуберкульозні препарати у хворих на хіміорезистентний туберкульоз". Thesis, Державна наукова установа «Науково-практичний центр профілактичної та клінічної медицини» Державного управління справами, 2019. https://essuir.sumdu.edu.ua/handle/123456789/81283.

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Кількість зареєстрованих побічних реакці досягає зазначеному Всесвітньою організацією охорони здоров'я (44-60 %) при лікуванні хіміорезистентного туберкульозу. Слід звертати увагу на моніторинг та реєстрацію побічних реакцій, що сприятиме своєчасному та повноцінному їх лікуванню, а відтак – підвищить ефективність лікування туберкульозу взагалі.

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Liu, Zhongqiu. "Mechanism of pharmacokinetic interaction between paeoniflorin and sinomenine." HKBU Institutional Repository, 2006. http://repository.hkbu.edu.hk/etd_ra/720.

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Humble, Mats B. "Obsessive-compulsive disorder, serotonin and oxytocin : treatment response and side effects." Doctoral thesis, Örebro universitet, Institutionen för medicinska vetenskaper, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-51438.

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Obsessive-compulsive disorder (OCD), with a prevalence of 1-2 %, frequently leads a chronic course. Persons with OCD are often reluctant to seek help and, if they do, their OCD is often missed. This is unfortunate, since active treatment may substantially improve social function and quality of life. Serotonin reuptake inhibitors (SRIs) have welldocumented efficacy in OCD, but delayed response may be problematic. Methods to predict response have been lacking. Because SRIs are effective, pathophysiological research on OCD has focussed on serotonin. However, no clear aberrations of serotonin have

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Howes, Dr Oliver. "The endocrine side effects of antipsychotic medication: prevalence, impact and treatment." Thesis, University of Oxford, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.491902.

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Antipsychotic drugs have been known to have effects on the endocrine system since their introduction to clinical practice. However, until recently there has been little systematic investigation of the prevalence and end-organ effects of endocrine disturbance in people taking antipsychotic medications. This thesis presents a series of studies that investigate glucose-insulin homeostasis, hypothalamic-pituitary-gonadal (HPG) axis function, and the relationship between abnonnalities of the HPG axis and sexual function, bone mineral density (BMD), and glucose-insulin homeostasis in patients taking

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