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1

Peak, Lizabeth. Sickle cell disease. Detroit: Lucent Books, 2008.

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2

Peak, Lizabeth. Sickle cell disease. Detroit: Lucent Books, 2008.

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3

Serjeant, Graham R. Sickle cell disease. 2nd ed. Oxford: Oxford University Press, 1992.

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4

Sickle cell disease. Oxford: Oxford University Press, 1985.

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5

F, Whitten Charles, Bertles John F. 1925-, National Association for Sickle Cell Disease (U.S.), and New York Academy of Sciences., eds. Sickle cell disease. New York, N.Y: New York Academy of Sciences, 1989.

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6

Sickle cell disease. 2nd ed. Oxford: Oxford University Press, 1992.

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7

Samuel, Charache, and Johnson Cage S, eds. Sickle cell disease. Philadelphia: W.B. Saunders, 1996.

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8

Eboh, Winifred Oluchukwu. Sickle cell disease. (Birmingham): Birmingham Sickle Cell & Thalassaemia Centre, 1993.

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9

Jones, Phill. Sickle cell disease. New York: Chelsea House, 2008.

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10

McCormick, Marie, Henrietta Awo Osei-Anto, and Rose Marie Martinez, eds. Addressing Sickle Cell Disease. Washington, D.C.: National Academies Press, 2020. http://dx.doi.org/10.17226/25632.

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11

Understanding sickle cell disease. Jackson: University Press of Mississippi, 1995.

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12

P, Rodgers Griffin, ed. Sickle cell disease and thalassaemia. London: Baillière Tindall, 1998.

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13

author, Chilman-Blair Kim, and DeLoache Shawn author, eds. Medikidz explain sickle cell disease. London: Medikidz Ltd., 2013.

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14

Meier, Emily Riehm, Allistair Abraham, and Ross M. Fasano, eds. Sickle Cell Disease and Hematopoietic Stem Cell Transplantation. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-62328-3.

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15

Howard, Jo, and Paul Telfer. Sickle Cell Disease in Clinical Practice. London: Springer London, 2015. http://dx.doi.org/10.1007/978-1-4471-2473-3.

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16

Midence, Kenny. Sickle cell disease: A psychosocial approach. Oxford: Radcliffe Medical Press, 1994.

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17

National Heart, Lung, and Blood Institute. Division of Blood Diseases and Resources., ed. The Management of sickle cell disease. 4th ed. Bethesda, MD: The Institute, 2002.

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18

National Heart, Lung, and Blood Institute. Division of Blood Diseases and Resources. The management of sickle cell disease. 4th ed. Bethesda, MD: The Institute, 2002.

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19

Renaissance of sickle cell disease research in the genome era. London: Imperial College Press, 2007.

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20

N, Mankad Vipul, and Moore R. Blaine, eds. Sickle cell disease: Pathophysiology, diagnosis, and management. Westport, Conn: Praeger, 1992.

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21

Ennis, Sylvia. The natural choice: Sickle cell disease/ thalassaemia. New Delhi: B.Jain Publishers, 1994.

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22

My daughter's journey with sickle cell disease. New York, NY: Heavenly Minded Productions, 2014.

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23

Anionwu, Elizabeth N. Sickle cell disease: A guide for families. Harlow: Longman, 1991.

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24

Samuel, Charache, Lubin Bertram, Reid Clarice D, United States. Dept. of Health and Human Services., National Institutes of Health (U.S.), and United States. Public Health Service., eds. Management and therapy of sickle cell disease. 3rd ed. [Bethesda, Md.]: U. S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Heart, Lung, and Blood Institute, 1995.

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25

D, O'Malley Paul, ed. New developments in sickle cell disease research. New York: Nova Science Publishers, 2006.

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26

B, Jibril Harun, ed. Sickle cell disease: A guide for families. London: Collins, 1986.

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27

1932-, Hurtig Anita Landau, and Viera Carol Therese 1952-, eds. Sickle cell disease: Psychological and psychosocial issues. Urbana: University of Illinois Press, 1986.

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28

Al-Jamʼa, Ali H. Management manual of sickel cell disease. [Saudi Arabia: Qatif Central Hospital], 1992.

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29

Sickle cell disease: A guide for health workers, patients and carers. London: Faber, 1990.

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30

Rosse, Wendell F. Transfusion support for patients with sickle cell disease. Bethesda, Md: AABB Press, 1998.

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31

Managing sickle cell disease in low-income families. Philadelphia: Temple University Press, 1994.

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32

Alvin, Silverstein, Silverstein Virginia B, and Nunn Laura Silverstein, eds. What you can do about sickle cell disease. New York, NY: Enslow Publishing, 2016.

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33

Society, Sickle Cell, ed. Sickle cell disease: The need for improved services. 3rd ed. London: Sickle Cell Society, 1991.

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34

Alan, Sacerdote, ed. Hope and destiny: The patient's and parent's guide to sickle cell disease and sickle cell trait. Roscoe, Ill: Hilton Pub. Co., 2002.

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35

Alan, Sacerdote, ed. Hope and destiny: The patient's and parent's guide to sickle cell disease and sickle cell trait. Roscoe, Ill: Hilton Pub. Co., 2006.

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36

Acuña-Castroviejo, Darío, and Iryna Rusanova. Sickle cell disease: A new vision for an old problem. Hauppauge] New York: Nova Biomedical, 2013.

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37

Szabova, Alexandra, and Kenneth R. Goldschneider. Sickle Cell Disease. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199764495.003.0040.

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0.2% of African-Americans have sickle cell anemia while, with 8% to 10% have sickle cell trait. This chapter provides an overiew of the etiology, pathophysiology, and treatment of sickle cell anemia as they affect anesthetic management—before, during, and after surgery.
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38

Ng, Ann, and Erin S. Williams. Sickle Cell Disease. Edited by Erin S. Williams, Olutoyin A. Olutoye, Catherine P. Seipel, and Titilopemi A. O. Aina. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190678333.003.0033.

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Sickle cell anemia (sickle cell disease) is a common hemoglobinopathy with anywhere from 90,000 to 100,000 Americans affected. This chronic condition has a predominance in populations of African descent, occurring in approximately 1 out of 365 African American births, compared to 1 out of 16,300 Hispanic births. The sickle cell trait can be detected in 1 of 13 African American births. One of the most common complications associated with sickle cell anemia, vaso-occlusive crises by sickled cells, results in severe pain. Other issues associated with this condition include acute chest syndrome, lung infections, end organ damage, and stroke. With improvements in the management and prevention of pain crises, infection, and other systemic involvement, these patients are living longer, thus increasing the potential for surgical needs. Whether it is for routine surgeries or surgeries that are due to the natural history of the disease; the pediatric anesthesiologist must be knowledgeable of the management of these patients in order to prevent morbidity and mortality.
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39

Serjeant, Graham R. Sickle Cell Disease. Oxford University Press, USA, 1988.

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40

Anionwu, Elizabeth, and H. Jibril. Sickle Cell Disease. Longman, 1986.

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41

Franklin, Andrew. Sickle Cell Disease. Edited by Matthew D. McEvoy and Cory M. Furse. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190226459.003.0084.

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Sickle cell disease, a hemoglobinopathy that affects multiple organ systems, is a complex disease entity that presents unique challenges during the perioperative period. The hallmark of sickle cell disease, vaso-occlusion, results from sickling of erythrocytes containing hemoglobin of abnormal conformation due to genetically mutated beta globin genes. The perioperative clinician must properly care for acute sickle cell crises including acute painful episodes and acute chest syndrome, and safely care for the sickle cell patient through the preoperative, intraoperative, and postoperative phases of surgical treatment. Both acute painful episodes and acute chest syndrome result from vaso-occlusive crises, and early stabilization of these emergencies is crucial to ensuring a positive patient outcome. The singular perioperative objective for the care of sickle cell disease patients is both simple and daunting: to achieve physiologic homeostasis in patients with preexisting multiorgan dysfunction undergoing a series of physiologic insults during and after surgery.
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42

Ferrari, Lynne R. Sickle Cell Disease. Edited by Kirk Lalwani, Ira Todd Cohen, Ellen Y. Choi, and Vidya T. Raman. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190685157.003.0051.

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Sickle cell anemia is a disease that combines molecular biology, clinical features, biochemistry, pathology, natural selection, population genetics, gene expression, and genomics and is the world’s most common life-threatening monogenic disorder. Clinical features include anemia; painful crisis especially in fingers, chest, and long bones; hemolysis; splenic infarction resulting in functional asplenia; and microinfarction leading to neurologic and renal impairment. The maintenance of adequate body temperature with active warming devices and warmed intravenous fluids, monitoring hydration and urine output, providing supplemental oxygen, and limiting surgical and anesthesia times to reduce pulmonary complications constitute the best management for patients with sickle cell disease.
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43

Anionwu, Elizabeth, and H. Jibril. Sickle Cell Disease. 2nd ed. Longman, 1992.

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44

Alebiosu, Christopher Olutayo. Sickle Cell Disease. Cambridge Scholars Publishing, 2020.

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45

Midence, Kenny. Sickle Cell Disease. Scovill-Paterson, 1994.

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46

Gladwin, Mark T., Gregory J. Kato, and Enrico M. Novelli. Sickle Cell Disease. McGraw-Hill Education, 2021.

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47

LaPierre, Yvette. Handling Sickle Cell Disease. ABDO Publishing Company, 2021.

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48

Sickle Cell Disease Patient. Tettah-A'Domeno Co, 1998.

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49

Understanding Sickle Cell Disease. University Press of Mississippi, 2009.

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50

GLADWIN. Sickle Cell Disease (ie). McGraw-Hill Education, 2021.

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