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Papafotiou, K., J. D. Carter, and C. Stough. "An evaluation of the sensitivity of the Standardised Field Sobriety Tests (SFSTs) to detect impairment due to marijuana intoxication." Psychopharmacology 180, no. 1 (December 24, 2004): 107–14. http://dx.doi.org/10.1007/s00213-004-2119-9.
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Li, Helei, Yining Wang, Xiaolong Sun, Wei Tian, Jingjing Xu, and Jiannan Wang. "Steady-State Behavior and Endothelialization of a Silk-Based Small-Caliber Scaffold In Vivo Transplantation." Polymers 11, no. 8 (August 3, 2019): 1303. http://dx.doi.org/10.3390/polym11081303.
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A silk-based small-caliber tubular scaffold (SFTS), which is fabricated using a regenerated silk fibroin porous scaffold embedding a silk fabric core layer, has been proved to possess good cell compatibility and mechanical properties in vitro. In this study, the endothelialization ability and the steady-state blood flow of SFTSs were evaluated in vivo by implanting and replacing a common carotid artery in a rabbit. The results of the color doppler ultrasound and angiographies showed that the blood flow was circulated in the grafts without aneurysmal dilations or significant stenoses at any time point, and ran stronger and close to the autologous blood vessel from one month after implantation. The SFTSs presented an initial tridimensionality without being distorted or squashed. SEM and immunohistochemistry results showed that a clear and discontinuous endodermis appeared after one month of implantation; when implanted for three months, an endothelial layer fully covered the inner surface of SFTSs. RT-PCR results indicated that the gene expression level of CD31 in SFTSs was 45.8% and 75.3% by that of autologous blood vessels at 3 months and 12 months, respectively. The VEGF gene showed a high expression level that continued to increase after implantation.
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Sun, Xiaolong, Yunxia Hao, Qiongyu Wang, Fenglin Dong, and Jiannan Wang. "Cell growth and proliferation on the interface of a silk fabric tubular scaffold." Textile Research Journal 86, no. 20 (July 20, 2016): 2193–201. http://dx.doi.org/10.1177/0040517515622146.
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A silk fibroin tubular scaffold (SFTS) has been designed and fabricated using silk fabric and regenerated silk fibroin, and used in the construction of artificial blood vessels. As a replacement for blood vessels, scaffolds should have a suitable interface for the adherence and proliferation of vascular cells, and the pore structure of the internal surface is one of most important factors. In this article, we investigate the effect of SFTSs with different pore structures on cells growth. Pore structures were controlled by adjusting the concentration of both the silk fibroin and the polyethylene glycol diglycidyl ether cross-linker as well as the freezing temperature. Intuitive cell fluorescence imaging and MTT assays on fibroblasts and human umbilical vein endothelial cells (HUVEC) were used to probe interactions with internal surfaces of differing pore diameter and density. The results showed that SFTSs fabricated under different conditions exhibited no cytotoxicity. Furthermore, fibroblasts were highly migratory, occupied the interface and could bridge the macropores well when the pore diameter was 50 ∼ 75 µm. SFTSs with micropores of about 30 ∼ 50 µm in diameter were deemed suitable for the growth and proliferation of HUVECs.
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TAKAHASHI, Toru. "Severe fever with thrombocytopenia syndrome (SFTS) and SFTS virus." Uirusu 65, no. 1 (2015): 7–16. http://dx.doi.org/10.2222/jsv.65.7.
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KIKUTANI, TAKESHI. "IYC2011, JUCST and SFSTJ." FIBER 67, no. 8 (2011): P.213. http://dx.doi.org/10.2115/fiber.67.p_213.
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Charatsari, Chrysanthi, Fotis Kitsios, and Evagelos D. Lioutas. "Short food supply chains: the link between participation and farmers' competencies." Renewable Agriculture and Food Systems 35, no. 6 (September 11, 2019): 643–52. http://dx.doi.org/10.1017/s1742170519000309.
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AbstractResearch on short food supply chains (SFSCs) has experienced a remarkable growth during recent years, offering ample evidence that the creation of such alternative food distribution networks can bring multiple benefits to both farmers and consumers. Nevertheless, farmers' engagement in SFSCs is still limited in many countries. Two studies designed to illustrate the role of competencies in the development of SFSCs are reported in this paper. The first one assessed the influence of farmers' self-perceived competencies on their willingness to participate in SFSCs. The second examined whether the engagement in SFSCs affects the levels of participants' competency needs. Study 1 revealed that willingness to participate in SFSCs is affected by the levels of farmers' competencies on issues pertaining to management, entrepreneurship, marketing, networking and cooperation. Although other factors such as farmers' citizenship behavior, their environmental concern and the perception that engagement in SFSCs can increase farm income are also associated with this willingness, self-perceived competencies represent the most important set of predictors. Study 2 uncovered that participation in SFSCs increases farmers' needs in all the above-mentioned categories of competencies. Taken together, these results indicate that farmers' competencies significantly affect their involvement in SFSCs, and that engagement in SFSCs augments competency needs, thus highlighting the importance of creating spaces that help farmers develop and exploit new capabilities.
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Schreuders, Michael, Bas van den Putte, Martin Mlinarić, Nora Mélard, Julian Perelman, Matthias Richter, Arja Rimpela, Mirte A. G. Kuipers, Vincent Lorant, and Anton E. Kunst. "The Association Between Smoke-Free School Policies and Adolescents’ Perceived Antismoking Norms: Moderation by School Connectedness." Nicotine & Tobacco Research 22, no. 11 (November 14, 2019): 1964–72. http://dx.doi.org/10.1093/ntr/ntz212.
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Abstract Introduction Many European schools implement smoke-free school policies (SFSPs). SFSPs may decrease adolescent smoking by causing adolescents to perceive stronger antismoking norms, yet there exists no quantitative evidence that indicates for which norms and for whom such effects may occur. This study therefore assessed to what extent adolescents’ perceived antismoking norms among best friends, teachers, and society at large were associated with SFSPs, and whether these associations were moderated by adolescents’ level of school connectedness. Aims and Methods Survey data were collected in 2016/2017 on 10,653 adolescents aged 14–16 years old and 315 staff members in 55 schools from seven European cities. Associations of adolescent-perceived SFSPs and staff-reported SFSPs with best friend, teacher, and societal antismoking norms were estimated in multilevel logistic regression models, adjusted for demographics and school-level smoking prevalence. We tested for interaction between school connectedness and SFSPs. Results Adolescent-perceived SFSPs were positively associated with antismoking norms by teachers (odds ratio [OR]: 1.46, 95% confidence interval [CI]: 1.15–1.85), were negatively associated with antismoking norms by best friends (OR: 0.81, 95% CI: 0.67–0.99), but were not significantly associated with antismoking norms by society at large (OR: 0.87, 95% CI: 0.74–1.02). All interaction tests between adolescent-perceived SFSPs and school connectedness were nonsignificant. Staff-reported SFSPs were not associated with any norm and showed no significant interaction with school connectedness. Conclusions We found that SFSPs are associated with adolescents’ perception of more antismoking norms by teachers, but less antismoking norms by best friends, irrespective of adolescents’ level of school connectedness. Implications Smoke-free school policies, just as many other tobacco control policies, are assumed to foster adolescents’ perception of antismoking norms. Still, current evidence does not demonstrate which antismoking norms may be influenced by SFSPs and whether this influence is equal for adolescents with different levels of school connectedness. This study suggests that SFSPs foster adolescents’ perception of antismoking norms by teachers, but may concurrently lead to the perception of less antismoking norms by best friends, irrespective of adolescents’ school connectedness. SFSPs may therefore need to be complemented with interventions that target antismoking norms in adolescent peer groups.
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Michel-Villarreal, Rosario, Eliseo Luis Vilalta-Perdomo, Maurizio Canavari, and Martin Hingley. "Resilience and Digitalization in Short Food Supply Chains: A Case Study Approach." Sustainability 13, no. 11 (May 24, 2021): 5913. http://dx.doi.org/10.3390/su13115913.
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The interest in short food supply chains (SFSCs) has grown significantly in the last decade, notably in respect of their potential role to achieve more sustainable food chains. However, a major barrier to achieving sustainable supply chains is the uncertainty associated with supply chain activities. Therefore, this paper aims to explore the different resilience capabilities that SFSCs possess and the potential role of digital technologies as enablers of SFSCs’ resilience. Using a case study research approach, semi-structured interviews were conducted in two SFSCs in Mexico. Collected data were analyzed using thematic analysis. Findings suggest that SFSCs possess the supply chain resilience (SC resilience) capabilities investigated here, namely flexibility, redundancy, collaboration, visibility and agility. A key finding is the importance of low-cost digital technologies (including freeware and social media) that can support flexibility, collaboration, visibility and agility. These findings raise important implications for SFSCs actors exploring opportunities to improve their collective resilience. This study expands the current literature by proposing a conceptual framework that summarizes a wide variety of strategies that support SC resilience capabilities in the context of SFSCs.
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Sizikova, T. E., V. N. Lebedev, V. B. Pantukhov, and S. V. Borisevich. "Severe fever with thrombocytopenia syndrome: the disease, caused by the novel phlebovirus." Problems of Virology, Russian journal 62, no. 2 (April 20, 2017): 60–65. http://dx.doi.org/10.18821/0507-4088-2017-62-2-60-65.
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Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by a new virus (SFTS virus) reported to be endemic to central and northeastern parts of China. SFTS virus, which is classified into the genus Phlebovirus (the Bunyaviridae family), is suspected to be a tick-borne virus owing to evidence in two species of ticks: Haemaphysalis longicornis and Rhipicephalus microplus. SFTS virus is detected among many species of domestic animals in China. The clinical symptoms of SFTS include fever, thrombocytopenia, leucocytopenia, gastrointestinal symptoms, neural symptoms, bleeding tendency. The fatality rate of SFTS is 6-30%. Person-to-person transmission of SFTS virus is possible through blood contact. Clinical and epidemiological studies of SFTS, the cases of SFTS outside China, person-to-person transmission of SFTS virus, evolutionary and molecular analysis of the emergent SFTS virus, and risk assessment of human infection with a novel phlebovirus are considered in this review.
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Wubben, E. F. M., M. Fondse, and S. Pascucci. "The importance of stakeholder-initiatives for business models in short food supply chains: the case of the Netherlands." Journal on Chain and Network Science 13, no. 2 (January 1, 2013): 139–49. http://dx.doi.org/10.3920/jcns2013.1004.
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While the interest in Short Food Supply Chains (SFSCs) is growing, we still await management studies that explore the impact of stakeholders of SFSCs in substantial numbers. This article investigates the differences in the business models of SFSCs that may be attributed to the initiator-stakeholder, interacting with other stakeholders. Essential to business models are the value proposition, value creation and value capture, but it is the ambition of the initiator-stakeholder that starts a SFSC. Initiator-stakeholders of 57 SFSCs were interviewed on a combination of both multiple choice and open questions. The data converges on three categories of business models. First and foremost, a large majority of SFSCs is driven by the aim of the initiator-stakeholder to increase economic viability, uses the market as governance structure, resulting in profit margins likely to be above margins in conventional business. Two other categories of business models of SFSCs group around the theme of producer-support, and, producer-consumer interaction, respectively.
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Walter, Franziska, Lena Döhring, and Axel Kobelt-Pönicke. "Die Erfassung der Beschwerdenvalidität von psychischen Störungen: Die diagnostische Güte des SFSS im Vergleich zum BEVA." Zeitschrift für Psychiatrie, Psychologie und Psychotherapie 68, no. 2 (March 2020): 70–80. http://dx.doi.org/10.1024/1661-4747/a000406.
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Zusammenfassung. Die vorliegende Studie ermittelt, ob der Beschwerdenvalidierungstest SFSS als Screening geeignet ist, um negative Antwortverzerrungen bei Patient_innen mit psychischen Störungen zu erfassen. Darüber hinaus soll die Interrater-Reliabilität des SFSS und einem weiteren Beschwerdenvalidierungstest – dem BEVA – für unterschiedliche Cut-Off-Werte des SFSS analysiert werden. Die Stichprobe ( N = 187) besteht aus Patient_innen mit einer Depression, einer gesunden Kontrollgruppe und Instruierten Simulant_innen. Das Analogstudiendesign wurde genutzt, um die Gruppenunterschiede im Gesamtwert des SFSS, den Cut-Off-Wert des SFSS, die diagnostische Güte des SFSS und die Übereinstimmung von SFSS und BEVA zu überprüfen. Die Ergebnisse zeigten, dass sich die Gruppen im Gesamtwert des SFSS signifikant unterscheiden. Die Instruierten Simulant_innen wiesen den höchsten, die Teilnehmenden der gesunden Kontrollgruppe den niedrigsten Gesamtwert im SFSS auf. Anhand der Daten der Instruierten Simulant_innen und der klinischen Stichprobe konnten mithilfe einer ROC-Analyse zwei mögliche Cut-Off-Werte für den SFSS ermittelt werden. Bei einem Cut-Off-Wert von 18 beträgt die Sensitivität .87, die Spezifität .45, der positiv prädiktive Wert .60 und der negativ prädiktive Wert .79. Für den Cut-Off-Wert von 24 können folgende Werte ermittelt werden: Eine Sensitivität von .62, eine Spezifität von .78, ein positiv prädiktiver Wert von .72, ein negativ prädiktiver Wert von .68. Die höchste Interrater-Reliabilität für den SFSS und BEVA kann für einen Cut-Off-Wert im SFSS von 24 berechnet werden (κ = .478). Der Cut-Off-Wert des SFSS sollte für den klinischen Kontext angepasst werden. Die Ergebnisse zeigten jedoch, dass der SFSS als ein sensitives Screening eingesetzt werden kann. Da der BEVA ein sehr spezifisches Verfahren darstellt, konnte die höchste Übereinstimmung mit dem SFSS bei einem Cut-Off-Wert von 24 erreicht werden. Die Verfahren könnten im klinischen Kontext gemeinsam angewendet werden, um die Diagnostik von negativen Antwortverzerrungen weiterhin zu verbessern.
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Kim, Namhee, Kye-Hyung Kim, Su Jin Lee, Sang-Hyuk Park, In-Suk Kim, Eun Yup Lee, and Jongyoun Yi. "Bone marrow findings in severe fever with thrombocytopenia syndrome: prominent haemophagocytosis and its implication in haemophagocytic lymphohistiocytosis." Journal of Clinical Pathology 69, no. 6 (November 16, 2015): 537–41. http://dx.doi.org/10.1136/jclinpath-2015-203417.
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AimsSevere fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne disease caused by the SFTS virus; primary manifestations are fever, thrombocytopenia, leukopenia and gastrointestinal symptoms. Before an aetiological diagnosis is made, SFTS patients can undergo bone marrow examination due to cytopenias. Although several studies have reported on bone marrow examination in SFTS patients, most do not provide adequate details. Bone marrow findings in SFTS patients were investigated in this study.MethodsAn observational study was conducted in SFTS patients who were hospitalised between 2013 and 2014 in two university hospitals in South Korea. Patients were included in the study if SFTS was confirmed by real-time PCR for the SFTS virus and a bone marrow examination was conducted. The morphologic findings of the bone marrow samples were reviewed.ResultsThree cases met the study inclusion criteria. One patient died of multiple organ failure. Haemophagocytosis was evident in the bone marrow samples of all three patients. Histiocytic hyperplasia and haemophagocytosis were more pronounced in the fatal case. One patient was diagnosed as having haemophagocytic lymphohistiocytosis.ConclusionsHaemophagocytosis in the bone marrow of SFTS patients may be common. In SFTS endemic areas, SFTS should be one of the differential diagnoses of fever of unknown origin with haemophagocytosis in the bone marrow.
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Neff, Ellen P. "Aged ferrets for SFTS." Lab Animal 48, no. 4 (March 20, 2019): 112. http://dx.doi.org/10.1038/s41684-019-0276-z.
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Yoshikawa, Tomoki. "Vaccine Development for Severe Fever with Thrombocytopenia Syndrome." Viruses 13, no. 4 (April 6, 2021): 627. http://dx.doi.org/10.3390/v13040627.
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Severe fever with thrombocytopenia syndrome (SFTS), which is caused by SFTS virus (SFTSV), is a tick-borne emerging zoonosis with a high case-fatality rate. At present, there is no approved SFTS vaccine, although the development of a vaccine would be one of the best strategies for preventing SFTS. This article focused on studies aimed at establishing small animal models of SFTS that are indispensable for evaluating vaccine candidates, developing these vaccine candidates, and establishing more practical animal models for evaluation. Innate immune-deficient mouse models, a hamster model, an immunocompetent ferret model and a cat model have been developed for SFTS. Several vaccine candidates for SFTS have been developed, and their efficacy has been confirmed using these animal models. The candidates consist of live-attenuated virus-based, viral vector-based, or DNA-based vaccines. SFTS vaccines are expected to be used for humans and companion dogs and cats. Hence for practical use, the vaccine candidates should be evaluated for efficacy using not only nonhuman primates but also dogs and cats. There is no practical nonhuman primate model of SFTS; however, the cat model is available to evaluate the efficacy of these candidate SFTS vaccines on domesticated animals.
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Park, Eun-sil, Osamu Fujita, Masanobu Kimura, Akitoyo Hotta, Koichi Imaoka, Masayuki Shimojima, Masayuki Saijo, Ken Maeda, and Shigeru Morikawa. "Diagnostic system for the detection of severe fever with thrombocytopenia syndrome virus RNA from suspected infected animals." PLOS ONE 16, no. 1 (January 28, 2021): e0238671. http://dx.doi.org/10.1371/journal.pone.0238671.
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Background Severe fever with thrombocytopenia syndrome virus (SFTSV) causes severe hemorrhagic fever in humans and cats. Clinical symptoms of SFTS-infected cats resemble those of SFTS patients, whereas SFTS-contracted cats have high levels of viral RNA loads in the serum and body fluids. Due to the risk of direct infection from SFTS-infected cats to human, it is important to diagnose SFTS-suspected animals. In this study, a reverse transcription polymerase chain reaction (RT-PCR) was newly developed to diagnose SFTS-suspected animals without non-specific reactions. Methodology/principle findings Four primer sets were newly designed from consensus sequences constructed from 108 strains of SFTSV. A RT-PCR with these four primer sets successfully and specifically detected four clades of SFTSV. Their limits of detection are 1–10 copies/reaction. Using this RT-PCR, 5 cat cases among 56 SFTS-suspected animal cases were diagnosed as SFTS. From these cats, IgM or IgG against SFTSV were detected by enzyme-linked immunosorbent assay (ELISA), but not neutralizing antibodies by plaque reduction neutralization titer (PRNT) test. This phenomenon is similar to those of fatal SFTS patients. Conclusion/significance This newly developed RT-PCR could detect SFTSV RNA of several clades and from SFTS-suspected animals. In addition to ELISA and PRNT test, the useful laboratory diagnosis systems of SFTS-suspected animals has been made in this study.
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Silvas, Jesus A., Vsevolod L. Popov, Adriana Paulucci-Holthauzen, and Patricia V. Aguilar. "Extracellular Vesicles Mediate Receptor-Independent Transmission of Novel Tick-Borne Bunyavirus." Journal of Virology 90, no. 2 (October 28, 2015): 873–86. http://dx.doi.org/10.1128/jvi.02490-15.
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ABSTRACTSevere fever with thrombocytopenia syndrome (SFTS) virus is a newly recognized member of the genusPhlebovirusin the familyBunyaviridae. The virus was isolated from patients presenting with hemorrhagic manifestations and an initial case fatality rate of 12 to 30% was reported. Due to the recent emergence of this pathogen, there is limited knowledge on the molecular virology of SFTS virus. Recently, we reported that the SFTS virus NSs protein inhibited the activation of the beta interferon (IFN-β) promoter. Furthermore, we also found that SFTS virus NSs relocalizes key components of the IFN response into NSs-induced cytoplasmic structures. Due to the important role these structures play during SFTS virus replication, we conducted live cell imaging studies to gain further insight into the role and trafficking of these cytoplasmic structures during virus infection. We found that some of the SFTS virus NSs-positive cytoplasmic structures were secreted to the extracellular space and endocytosed by neighboring cells. We also found that these secreted structures isolated from NSs-expressing cells and SFTS virus-infected cells were positive for the viral protein NSs and the host protein CD63, a protein associated with extracellular vesicles. Electron microscopy studies also revealed that the isolated CD63-immunoprecipitated extracellular vesicles produced during SFTS virus infection contained virions. The virions harbored within these structures were efficiently delivered to uninfected cells and were able to sustain SFTS virus replication. Altogether, these results suggest that SFTS virus exploits extracellular vesicles to mediate virus receptor-independent transmission to host cells and open the avenue for novel therapeutic strategies against SFTS virus and related pathogens.IMPORTANCESFTS virus is novel bunyavirus associated with hemorrhagic fever illness. Currently, limited information is available about SFTS virus. In the present study, we demonstrated that extracellular vesicles produced by SFTS virus-infected cells harbor infectious virions. We sought to determine whether these “infectious” extracellular vesicles can mediate transmission of the virus and confirmed that the SFTS virions were efficiently transported by these secreted structures into uninfected cells and were able to sustain efficient replication of SFTS virus. These results have significant impact on our understanding of how the novel tick-borne phleboviruses hijack cellular machineries to establish infection and point toward a novel mechanism for virus replication among arthropod-borne viruses.
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Karki, Rita. "Sexual Violence and Consequences of Unintended Pregnancy among the Street Based Sex Workers in Nepal." Journal of Development and Administrative Studies 25, no. 1-2 (December 31, 2017): 62–75. http://dx.doi.org/10.3126/jodas.v25i1-2.23443.
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Unintended pregnancy, concerning particularly in street based female sex workers (SFSWs) who solicit in streets or public places for sex, is closely associated with sexual relation involuntarily and often unwillingly. It seriously challenges in physical, mental, social and economic wellbeing hazardously. The aim of the study is to explore the sexual violence, use of contraception and events and consequences of unintended pregnancy, the study of which is lacking up to the present time in Nepal. A cross-sectional study is conducted using mixed method consisting of questionnaire-based survey with 110 SFSWs along with case studies and observations. Respondents are identified by using snowball sampling technique. The findings are presented descriptively after arranging in different themes. Results show that almost all the SFSWs had experienced sexual violence at least once after involving in sex trade; 74 percent had threatening experience and 87 percent induced abortion among the unintended pregnancy from clients. The results indicate that the forced prostitution and threatening experience to follow clients' interest and unprotected sex are significantly hazardous for SFSWs' overall health. High prevalence of sexual violence and unintended pregnancy result in poor health outcomes for SFSWs. Assuring the sexual health and life safety of SFSWs from group sexual violence is another risk area for further exploration.
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Oh, Hyunjoo, Jeong Rae Yoo, Gil Myeong Seong, Sun Hyung Kim, and Sang Taek Heo. "A Fatal Pulmonary Event during Plasma Exchange in a Patient with Severe Fever with Thrombocytopenia Syndrome." Korean Journal of Medicine 95, no. 3 (June 1, 2020): 211–15. http://dx.doi.org/10.3904/kjm.2020.95.3.211.
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Severe fever with thrombocytopenia syndrome (SFTS) caused by the SFTS virus (SFTSV), a novel <i>Phlebovirus</i>, is endemic to South Korea, central and northeastern China, and western Japan. SFTS poses a threat to public health because of its high mortality and secondary transmission. Ticks and domestic animals are hosts for SFTSV in endemic areas. There is no specific treatment for SFTS, and avoiding tick bites is the best way to prevent infection. Early therapeutic plasma exchange (TPE) is a rescue therapy in patients with rapidly progressive SFTS. Here, we present a patient with SFTS who was improving on TPE but died suddenly due to acute lung injury after TPE.
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Kanda, Kohei, Noriko Kinoshita, Satoshi Kutsuna, Keiji Nakamura, Ayako Okuhama, Akira Shimomura, Takeshi Inagaki, et al. "Residual and Late Onset Symptoms Appeared in a Patient with Severe Fever with Thrombocytopenia in a Convalescence Stage." Viruses 13, no. 4 (April 10, 2021): 657. http://dx.doi.org/10.3390/v13040657.
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Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease caused by Dabie bandavirus (formerly SFTS virus, SFTSV). Its manifestations during the convalescent phase have not been widely described. We report a patient presenting with hematospermia, fatigue, myalgia, alopecia, insomnia, and depression during the recovery phase of SFTS. Since these symptoms are widely observed in patients with viral hemorrhagic fevers, there might be common mechanisms between SFTS and other viral hemorrhagic fevers. Close monitoring may be required during the recovery phase of SFTS.
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Li, Fudong, Fan He, Jimin Sun, Yujia Zhai, Jianmin Jiang, and Junfen Lin. "Spatial and temporal analysis of severe fever with thrombocytopenia syndrome in Zhejiang Province, China, 2011 - 2015." Journal of Infection in Developing Countries 13, no. 01 (January 31, 2019): 35–43. http://dx.doi.org/10.3855/jidc.10373.
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Introduction: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease first discovered in northeast and central China in 2009, and SFTS cases increased year by year in China. This study aimed to identify the spatial and temporal clusters of SFTS in Zhejiang Province, China.
Methodology: We analyzed the surveillance data of SFTS in Zhejiang Province during 2011 - 2015. Descriptive statistics were used to analyze the general characteristics and overall trend of SFTS. Circular statistic method was utilized to identify the seasonality. Space–time scan analysis was performed to explore the high risk spatio-temporal clusters of SFTS cases at county level.
Results: A total of 194 confirmed SFTS cases were reported in Zhejiang Province during 2011 - 2015. We found a significant increase in overall time trend since 2011. The seasonality was statistically significant (P < 0.001), with a mean date (95% CI) of 21st June (12th ~ 30th in June). Totally 21 (23%) counties reported the occurrence of SFTS, which gradually spread throughout Zhejiang. Three spatio-temporal clusters were detected, with one principle cluster (Daishan County, RR 234.48, June 2013 - November 2015) and two secondary clusters (6 counties, RR 30.73, April - October in 2015; Anji County, RR 373.26, May 2014).
Conclusions: Our results suggested that SFTS has increased and spatially expanded over the past years, with a remarkable seasonality. Three spatio-temporal clusters were identified. These findings are important for the improvement of SFTS surveillance and control strategies.
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KAMEYAMA, MAKOTO, SHU MEGURO, OSAMU FUNAE, YOSHIHITO ATSUMI, and HIROYASU IKEGAMI. "The Presence of Limited Joint Mobility Is Significantly Associated with Multiple Digit Involvement by Stenosing Flexor Tenosynovitis in Diabetics." Journal of Rheumatology 36, no. 8 (June 16, 2009): 1686–90. http://dx.doi.org/10.3899/jrheum.081024.
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Objective.Diabetes is associated with several disorders of the hand, including stenosing flexor tenosynovitis (SFTS). The feature of SFTS in diabetics is a higher prevalence of multiple digit involvement. We examined the magnitude of the tendency for involvement of more digits by SFTS in diabetic patients than in nondiabetic patients, and attempted to clarify the factors influencing multiple digit involvement by SFTS in diabetics.Methods.The study comprised 302 diabetic patients with SFTS and 235 nondiabetic patients with SFTS. The total number of digits exhibiting SFTS within the 1-year period following the initial visit to the Department of Orthopaedic Surgery was investigated in a prospective manner. We compared the difference in the frequency of multiple digit involvement by SFTS between diabetic and nondiabetic patients using the chi-squared test. Multiple regression analysis was performed to examine the contribution of independent variables [defined as 12 factors including age, sex, type of diabetes, estimated duration of diabetes, HbA1c values, carpal tunnel syndrome, Dupuytren contracture, limited joint mobility (LJM), de Quervain's disease, diabetic retinopathy, diabetic nephropathy, and dyslipidemia] to the total number of digits affected by SFTS in diabetic patients.Results.Diabetic patients showed a significantly higher prevalence of multiple digit involvement than nondiabetic patients (p < 0.0001). Multiple regression analysis in diabetic patients revealed that the presence of LJM was positively associated with the prevalence of multiple digit involvement (r = 0.626, p < 0.0001).Conclusion.LJM in diabetics is closely associated with SFTS involving multiple digits.
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Giampietri, Elisa, Adele Finco, and Teresa Del Giudice. "Exploring consumers’ behaviour towards short food supply chains." British Food Journal 118, no. 3 (March 7, 2016): 618–31. http://dx.doi.org/10.1108/bfj-04-2015-0168.
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Purpose – Investigating the drivers of consumers’ behaviour towards purchasing in short food supply chains (SFSCs) and clarifying their relationships, the purpose of this paper is to test the theory of planned behaviour (TPB) in order to predict the intention and the behaviour under investigation. Design/methodology/approach – The research includes a literature review of SFSCs. To investigate all the variables (attitudes, subjective norms (SN), perceived behavioural control (PBC) and intention) underlying consumers’ behaviour towards buying in SFSCs, an exploratory survey with a TPB questionnaire and a principal component analysis have been carried out among university students in Italy. Using a system of simultaneous equations, the relationships among variables have been measured. Findings – Findings illustrate that both attitudinal variables (i.e. sustainability, typicality and loyalty), SN and PBC play a key role in the consumers’ intention, that has a predictive effect on behaviour instead of PBC. Originality/value – This paper fulfils the purpose to explain and predict post-modern consumers’ preferences towards SFSCs, in order to orient policy strategies to support SFSCs.
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Kim, Uh Jin, Tae hoon Oh, Bansuk Kim, Seong Eun Kim, Seung-Ji Kang, Kyung-Hwa Park, Sook-In Jung, and Hee-Chang Jang. "Hyperferritinemia as a Diagnostic Marker for Severe Fever with Thrombocytopenia Syndrome." Disease Markers 2017 (2017): 1–6. http://dx.doi.org/10.1155/2017/6727184.
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Severe fever with thrombocytopenia syndrome (SFTS) is an emerging viral disease in East Asia with high mortality. Few studies have examined markers that suggest SFTS in febrile patients. To determine useful biochemical markers for SFTS, patients aged 18 years or older with SFTS or microbiologically confirmed community-onset bacteremia with thrombocytopenia (BT) at presentation between June 2013 and December 2015 were included from two tertiary university hospitals in Republic of Korea retrospectively. Eleven patients with SFTS and 62 patients with bacteremia and thrombocytopenia were identified in the study period. Age and sex did not show significant difference among two groups. Fever was more commonly observed but comorbidities were less common in SFTS than in BT (P<0.05, each). The areas under the curves of serum ferritin, C-reactive protein, white blood cell count, serum procalcitonin, and fibrinogen were above 0.9, indicating the discriminative power of these biomarkers (1.000, 0.991, 0.963, 0.931, and 0.934, resp., allP<0.05). The optimal cutoff value of serum ferritin was 3,822 ng/mL in this study. These results suggest that hyperferritinemia is a typical laboratory feature of SFTS, and the serum ferritin level can be used as a marker for clinicians suspecting SFTS.
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Kim, Misun, Sang Taek Heo, Hyunjoo Oh, Suhyun Oh, Keun Hwa Lee, and Jeong Rae Yoo. "Prognostic Factors of Severe Fever with Thrombocytopenia Syndrome in South Korea." Viruses 13, no. 1 (December 23, 2020): 10. http://dx.doi.org/10.3390/v13010010.
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Severe fever with thrombocytopenia syndrome (SFTS), a tick-borne infectious disease, is difficult to differentiate from other common febrile diseases. Clinically distinctive features and climate variates associated with tick growth can be useful predictors for SFTS. This retrospective study (2013–2019) demonstrated the role of climatic factors as predictors of SFTS and developed a clinical scoring system for SFTS using climate variables and clinical characteristics. The presence of the SFTS virus was confirmed using reverse transcription polymerase chain reaction (RT-PCR) tests. In the univariate analysis, the SFTS-positive group was significantly associated with higher mean ambient temperature and humidity compared with the SFTS-negative group (22.5 °C vs. 18.9 °C; 77.9% vs. 70.7%, all p < 0.001). In the multivariate analysis, poor oral intake (Odds ratio [OR] 5.87, 95% CI: 2.42–8.25), lymphadenopathy (OR 7.20, 95% CI: 6.24–11.76), mean ambient temperature ≥ 20 °C (OR 4.62, 95% CI: 1.46–10.28), absolute neutrophil count ≤ 2000 cells/μL (OR 8.95, 95% CI: 2.30–21.25), C-reactive protein level ≤ 1.2 mg/dL (OR 6.42, 95% CI: 4.02–24.21), and creatinine kinase level ≥ 200 IU/L (OR 5.94, 95% CI: 1.42–24.92) were significantly associated with the SFTS-positive group. This study presents the risk factors, including ambient temperature and clinical characteristics, that physicians should consider when suspecting SFTS.
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KAWAGUCHI, HARUMA. "Can SFSTI Become a New One?" FIBER 59, no. 12 (2003): P.399. http://dx.doi.org/10.2115/fiber.59.p_399.
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Vittersø, Gunnar, Hanne Torjusen, Kirsi Laitala, Barbara Tocco, Beatrice Biasini, Peter Csillag, Matthieu Duboys de Labarre, et al. "Short Food Supply Chains and Their Contributions to Sustainability: Participants’ Views and Perceptions from 12 European Cases." Sustainability 11, no. 17 (September 3, 2019): 4800. http://dx.doi.org/10.3390/su11174800.
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The present food system faces major challenges in terms of sustainable development along social, economic and environmental dimensions. These challenges are often associated with industrialised production processes and longer and less transparent distribution chains. Thus, closer distribution systems through Short Food Supply Chains (SFSCs) may be considered as a sustainable alternative. This study explores the role of different types of SFSCs and their contribution to sustainability through participants’ (consumers, retailers and producers) views and perceptions. As part of the European H2020 project “Strength2Food” we conducted a cross-case analysis and examined 12 European SFSC cases from six countries: France, Hungary, Italy, Norway, Poland and the UK. We applied a mixed method approach including primary data collection, via in-depth interviews and customer surveys, as well as desk research. The findings suggest that, irrespective of the type of SFSC, a strong agreement among the participants were found on the contribution of SFSCs to social sustainability. However, participants’ views considerably differ regarding the economic and environmental dimensions of sustainability. These differences relate to the way the SFSCs were organised and to some degrees to regional differences attributed to the significance of SFSC in different parts of Europe. The article concludes that the spatial heterogeneity of SFSCs, including supply chain actor differences, different types and organisational forms of SFSCs as well as regional and territorial characteristics, must be taken into account and further emphasised in future policies aimed at strengthening European food chain sustainability.
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Karki, Rita. "Inconsistent use of condom: risky sexual behaviour among the street based sex workers in Kathmandu Valley." Nepal Population Journal 18, no. 17 (December 31, 2018): 65–72. http://dx.doi.org/10.3126/npj.v18i17.26378.
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The nature of profession of sex trade is multi partnered which leads the sex partners to unprotected sex. This study aims to explore the knowledge and experiences of STIs, practice and use of condom, reasons of not using it regularly and addiction situations among the street based female sex workers (SFSWs) in Kathmandu Valley. This study is a non-experimental research based on cross-sectional design. Mixed method was used to collect information with 110 SFSWs selected by using snow ball sampling techniques and presented descriptively after arranging in different themes. Among the SFSWs, 64.5 percent experienced STIs and 69 percent of them were unable to use condoms regularly. Most of the sex workers agree to unprotected sex when they are offered extra money and forced for sex by clients without condom, and another reason was lack of skill on SFSWs in using it properly. Knowingly or unknowingly SFSWs, clients and their life-partners are being victimized from practicing of risky sexual behaviour. The study suggests that touchy and broad awareness programs and compulsory rule to use male condom from clients’ side within safer indoor work space could be effective in helping to assure satisfying and safe sex.
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Pato, Maria Lúcia. "Short food supply chains – a growing movement. The case study of the Viseu Dão Lafões Region." Open Agriculture 5, no. 1 (December 11, 2020): 806–16. http://dx.doi.org/10.1515/opag-2020-0077.
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AbstractIn spite of the increasing attention being paid to short food supply chains (SFSCs), research in the area is still scarce, particularly in Portugal. Thus, based on a case study in Viseu Dão Lafões Region (VDLR), we intend to identify and discuss (emphasizing potentialities and constraints) the movement of SFSCs in the region. This case study is based on document analysis and interviews with agrifood baskets’ promotors. On the one hand, the results show the wide variety of SFSCs that exist in the region and the emergence of new forms of SFSCs like the agrifood baskets. On the other hand, the empirical research also emphasizes the environmental, economic, and sociocultural benefits of SFSCs that will have a positive impact on the well-being of producers, consumers, and/or on the whole region. However, the interviews have also exposed a (certain) limitation in terms of communication and marketing that may constraint these initiatives. From a practical point of view, it became clear that producers must do their best to develop their communication and marketing strategies; from a political point of view, local authorities should provide the necessary assistance to help implement training programmes and develop suitable communication and marketing skills.
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Charatsari, Chrysanthi, Fotis Kitsios, Amalia Stafyla, Dimitrios Aidonis, and Evagelos Lioutas. "Antecedents of farmers’ willingness to participate in short food supply chains." British Food Journal 120, no. 10 (October 1, 2018): 2317–33. http://dx.doi.org/10.1108/bfj-09-2017-0537.
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Purpose Despite the increasing consumers’ intent to support short food networks, the expansion of short food supply chains (SFSCs) remains limited. The purpose of this paper is to identify potential antecedents of farmers’ willingness to participate in SFSCs. Design/methodology/approach Using data from a sample of Greek farmers the authors examined whether farmers’ citizenship behaviour, the levels of their perceived competencies and the degree to which they feel accepted by their communities affect their willingness to engage in SFSCs. Findings Results indicate that producers’ citizenship behaviour does indeed have a positive impact on willingness to participate in SFSCs, whereas their perceptions of the acceptance they enjoy within their communities also significantly predict this willingness. On the contrary, self-perceived lack of communication and collaboration competencies diminishes this willingness. Originality/value To the best of our knowledge, this study is one of the first attempts to explore the role of farmers’ competencies in their willingness to participate in SFSCs. In addition, by integrating concepts derived from multiple disciplines, our work adds new factors in the wide spectrum of forces that impel or suppress farmers’ willingness to take part in alternative food distribution networks.
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Pradhan, P., E. Bozzo, and B. Paul. "Supergiant fast X-ray transients versus classical supergiant high mass X-ray binaries: Does the difference lie in the companion wind?" Astronomy & Astrophysics 610 (February 2018): A50. http://dx.doi.org/10.1051/0004-6361/201731487.
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We present a comparative study of stellar winds in classical supergiant high mass X-ray binaries (SgXBs) and supergiant fast X-ray transients (SFXTs) based on the analysis of publicly available out-of-eclipse observations performed with Suzaku and XMM-Newton. Our data set includes 55 observations of classical SgXBs and 21 observations of SFXTs. We found that classical SgXBs are characterized by a systematically higher absorption and luminosity compared to the SFXTs, confirming the results of previous works in the literature. Additionally, we show that the equivalent width of the fluorescence Kα iron line in the classical SgXBs is significantly larger than that of the SFXTs (outside X-ray eclipses). Based on our current understanding of the physics of accretion in these systems, we conclude that the most likely explanation of these differences is ascribed to the presence of mechanisms inhibiting accretion most of the time in SFXTs, thereby leading to a much less efficient photoionization of the stellar wind compared to classical SgXBs. We do not find evidence for the previously reported anticorrelation between the equivalent width of the fluorescence iron line and the luminosity of SgXBs.
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Elghannam, Ahmed, Francisco J. Mesias, Miguel Escribano, Lina Fouad, Andres Horrillo, and Alfredo J. Escribano. "Consumers’ Perspectives on Alternative Short Food Supply Chains Based on Social Media: A Focus Group Study in Spain." Foods 9, no. 1 (December 24, 2019): 22. http://dx.doi.org/10.3390/foods9010022.
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Nowadays, an increasing number of consumers are demanding more information and more direct contact with food producers in order to avoid the various intermediaries in the supply chain, thus improving food traceability and price transfer. This has led to the development of more direct (short) food supply chains (SFSCs). Although consumer preferences to use SFSCs rather than traditional (long) supply chains have been widely researched in the literature, this study brings a new approach with the use of social media sites to build online SFSCs. A focus group approach with a total of 32 participants was used in this study with the main objective to understand consumers’ awareness and acceptance of SFSCs. Special attention was given to the use of social media and electronic word of mouth (eWOM) as new approaches to support the creation of such alternative channels.
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Mizoe, Atsushi, Junya Sakaue, and Noriko Takahara. "Why does activated partial thromboplastin time prolongation occur in severe fever with thrombocytopenia syndrome?" BMJ Case Reports 13, no. 10 (October 2020): e235447. http://dx.doi.org/10.1136/bcr-2020-235447.
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Severe fever with thrombocytopenia syndrome (SFTS) is caused by infection with SFTS virus and this mortality rate is 16.2% to 30%. An 85-year-old male patient presented to the emergency department of the hospital with primary complaints of fever and consciousness disturbance. Haemophagocytic syndrome and prolonged activated partial thromboplastin time (APTT) without associated prolonged prothrombin time were observed, suggesting SFTS, which was eventually diagnosed. APTT-only prolongation has been reported previously with SFTS, but the mechanism is unknown. The absence of coagulation factors was determined by a cross-mixing study. In addition, examination of intrinsic coagulation factors showed reduced factor XI activity. These results suggest that factor XI is causally related to APTT-only prolongation in SFTS.
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Cohen, David. "Lamplighters admit weakly aperiodic SFTs." Groups, Geometry, and Dynamics 14, no. 4 (October 26, 2020): 1241–52. http://dx.doi.org/10.4171/ggd/579.
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Khiami, F. "JTS-SFTS : un projet ambitieux." Journal de Traumatologie du Sport 28, no. 4 (December 2011): 207. http://dx.doi.org/10.1016/j.jts.2011.10.011.
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Jeandel, Emmanuel, and Pascal Vanier. "Turing degrees of multidimensional SFTs." Theoretical Computer Science 505 (September 2013): 81–92. http://dx.doi.org/10.1016/j.tcs.2012.08.027.
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Boyle, Mike, Toke Meier Carlsen, and Søren Eilers. "Flow equivalence of G-SFTs." Transactions of the American Mathematical Society 373, no. 4 (January 7, 2020): 2591–657. http://dx.doi.org/10.1090/tran/7981.
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Ramdial, P. K., and A. Madaree. "Aggressive CD34-positive Fibrous Scalp Lesion of Childhood: Extrapulmonary Solitary Fibrous Tumor." Pediatric and Developmental Pathology 4, no. 3 (May 2001): 267–75. http://dx.doi.org/10.1007/s100240010140.
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Although solitary fibrous tumor (SFT) was originally described as a pleural tumor, an increasing number of extrapleural sites of SFTs have been documented. This has been attributed not only to the heightened awareness of the spectrum of histopathological features that characterizes SFTs but also to the recognition of the role of CD34 immunostaining in soft tissue tumors in general, and in SFTs in particular. Despite the large number of documented extrapleural SFTs in adults, cranial SFTs are rare, having been documented in the meninges, scalp, and infratemporal fossa. Extrapleural SFTs are, to date, an unrecognized entity in children. We document an aggressive fibrous scalp lesion in a 30-month-old female child that demonstrated features common to benign cranial fasciitis and SFT. However, based on bright, diffuse CD34 antigen immunopositivity, a diagnosis of SFT was made. The need to include the CD34 antigen stain in a panel of immunohistochemical markers used to assess spindle cell lesions of childhood is emphasized.
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Balafoutis, Athanasios T., Frits K. Van Evert, and Spyros Fountas. "Smart Farming Technology Trends: Economic and Environmental Effects, Labor Impact, and Adoption Readiness." Agronomy 10, no. 5 (May 21, 2020): 743. http://dx.doi.org/10.3390/agronomy10050743.
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Farming faces challenges that increase the adverse effects on farms’ economics, labor, and the environment. Smart farming technologies (SFTs) are expected to assist in reverting this situation. In this work, 1064 SFTs were derived from scientific papers, research projects, and industrial products. They were classified by technology readiness level (TRL), typology, and field operation, and they were assessed for their economic, environmental, and labor impact, as well as their adoption readiness from end-users. It was shown that scientific articles dealt with SFTs of lower TRL than research projects. In scientific articles, researchers investigated mostly recording technologies, while, in research projects, they focused primarily on farm management information systems and robotic/automation systems. Scouting technologies were the main SFT type in scientific papers and research projects, but variable rate application technologies were mostly located in commercial products. In scientific papers, there was limited analysis of economic, environmental, and labor impact of the SFTs under investigation, while, in research projects, these impacts were studied thoroughly. Further, in commercial SFTs, the focus was on economic impact and less on labor and environmental issues. With respect to adoption readiness, it was found that all of the factors to facilitate SFT adoption became more positive moving from SFTs in scientific papers to fully functional commercial SFTs, indicating that SFTs reach the market when most of these factors are addressed for the benefit of the farmers. This SFT analysis is expected to inform researchers on adapting their research, as well as help policy-makers adjust their strategy toward digitized agriculture adoption and farmers with the current situation and future trends of SFTs.
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Andino, Lizmarie, Philip T. Cagle, Bruno Murer, Li Lu, Helmut H. Popper, Francoise Galateau-Salle, Anna E. Sienko, Roberto Barrios, and Dani S. Zander. "Pleuropulmonary Desmoid Tumors: Immunohistochemical Comparison With Solitary Fibrous Tumors and Assessment of β-Catenin and Cyclin D1 Expression." Archives of Pathology & Laboratory Medicine 130, no. 10 (October 1, 2006): 1503–9. http://dx.doi.org/10.5858/2006-130-1503-pdticw.
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Abstract Context.—Desmoid tumors arising in the lung and pleura are extremely rare and can resemble other, more common neoplasms native to these sites. Alterations of the adenomatous polyposis coli/β-catenin pathway have been detected in sporadic desmoid tumors and have been associated with nuclear accumulation of β-catenin and overexpression of cyclin D1. Objective.—To analyze the expression of β-catenin and cyclin D1 in desmoid tumors and solitary fibrous tumors (SFTs), and to compare the utilities of these substances for distinguishing between these entities with those of other, more commonly used stains. Design.—Formalin-fixed, paraffin-embedded sections of 4 desmoid tumors (1 pulmonary, 1 pleural, 2 pleural/chest wall), and 5 benign and 6 malignant SFTs of the pleura were immunostained for β-catenin, cyclin D1, ALK1, CD34, vimentin, desmin, smooth muscle actin, muscle-specific actin, S100, and pancytokeratin. Staining intensity and the percentage of stained tumor cells were assessed semiquantitatively. Results.—Diffuse moderate or strong nuclear staining for β-catenin was found in all desmoid tumors, 4 of 5 benign SFTs, and 2 of 6 malignant SFTs. All cases except 1 benign SFT showed concurrent cytoplasmic staining. Nuclear and cytoplasmic cyclin D1 staining was increased in all groups. The best distinction between desmoid tumors and SFTs was provided by CD34 (desmoid tumors, 0/4; SFTs, 8/11) and smooth muscle actin (desmoid tumors, 4/4; SFTs, 0/11). Conclusions.—Our findings suggest that alterations in the adenomatous polyposis coli/β-catenin pathway and cyclin D1 dysregulation may contribute to the pathogenesis of pleuropulmonary desmoid tumors and SFTs. CD34 and smooth muscle actin stains are particularly useful for differentiating between pleuropulmonary desmoid tumors and SFTs.
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Sul, Hyoung, Na Ra Yun, Dong-Min Kim, Jieun Kim, Jian Hur, Sook In Jung, Seong-yeol Ryu, et al. "2186. Differentiation of Severe Fever with Thrombocytopenia Syndrome from Scrub Typhus." Open Forum Infectious Diseases 6, Supplement_2 (October 2019): S743—S744. http://dx.doi.org/10.1093/ofid/ofz360.1866.
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Abstract Background SFTS and scrub typhus have similar clinical features and difficult to differentiate. Thus, a study to develop a scoring system to differentiate between two diseases in a clinical setting before the confirmation of laboratory results was reported by Kim et al. However, the statistical power could be low because of low numbers of cases (21 SFTS, 91 scrub typhus), our study analyzed by increasing the number of cases to overcome these limitations. Methods We retrospectively collected data from 183 SFTS and 178 scrub typhus patients who visited the 21 hospitals in South Korea between October, 2013 and November, 2017. The study protocol was approved by the IRB of each institution. SFTS was diagnosed through detection of SFTS viral RNA using RT–PCR. Scrub typhus was diagnosed either detection of 56-kDa antigen of O. tsutsugamushi using nested PCR or ≥ 4 fold rise in IgM or IgG titer using indirect IFA. Statistical analyses were performed by using SPSS and Medcalc. Results To differentiate SFTS from scrub typhus, we applied the scoring system proposed by Kim et al. After multivariable logistic regression, altered mental status, leukopenia, prolonged aPTT, and normal CRP(≤ 1.0 mg/dL) were significantly associated with SFTS compared with scrub typhus. Each variable was scored by 1 point, with a total score of 0–4 points, the optimal cutoff value was > 1 for the ROC curve. A score > 1 had 92% sensitivity, 96% specificity for diagnosis of SFTS, with a ROC AUC of 0.974. Because the sensitivity was less than 95%, we changed the normal CRP criteria to ≤ 3.0 mg/dL. The modified scoring system had 97% sensitivity, 96% specificity for diagnosis of SFTS, with an AUC of 0.983, and it showed a statistically higher accuracy than original scoring system (P = 0.0487). In this study, four factors for predicting SFTS were newly developed: leukopenia, prolonged aPTT, normal CRP (≤3.0 mg/dL), and elevated CK (>1,000 IU/L). Our study scoring system had 97% sensitivity, 98% specificity for diagnosis of SFTS, with an AUC of 0.992, and it showed a statistically higher accuracy than original scoring system (P = 0.0308). Conclusion In conclusion, we can easily differentiate SFTS from scrub typhus by using our scoring system of leukopenia, prolonged aPTT, normal CRP, and elevated CK in the endemic area. Disclosures All authors: No reported disclosures.
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Mahmood, Tahir, Jabbar Ahmmad, Zeeshan Ali, Dragan Pamucar, and Dragan Marinkovic. "Interval Valued T-Spherical Fuzzy Soft Average Aggregation Operators and Their Applications in Multiple-Criteria Decision Making." Symmetry 13, no. 5 (May 9, 2021): 829. http://dx.doi.org/10.3390/sym13050829.
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This paper deals with uncertainty, asymmetric information, and risk modelling in a complex power system. The uncertainty is managed by using probability and decision theory methods. Multiple-criteria decision making (MCDM) is a very effective and well-known tool to investigate fuzzy information more effectively. However, the selection of houses cannot be done by utilizing symmetry information, because enterprises do not have complete information, so asymmetric information should be used when selecting enterprises. In this paper, the notion of soft set (SftS) and interval-valued T-spherical fuzzy set (IVT-SFS) are combined to produce a new and more effective notion called interval-valued T-spherical fuzzy soft set (IVT−SFSftS). It is a more general concept and provides more space and options to decision makers (DMs) for making their decision in the field of fuzzy set theory. Moreover, some average aggregation operators like interval-valued T-spherical fuzzy soft weighted average (IVT−SFSftWA) operator, interval-valued T-spherical fuzzy soft ordered weighted average (IVT−SFSftOWA) operator, and interval-valued T-spherical fuzzy soft hybrid average (IVT−SFSftHA) operators are explored. Furthermore, the properties of these operators are discussed in detail. An algorithm is developed and an application example is proposed to show the validity of the present work. This manuscript shows how to make a decision when there is asymmetric information about an enterprise. Further, in comparative analysis, the established work is compared with another existing method to show the advantages of the present work.
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Michel-Villarreal, Rosario, Eliseo Luis Vilalta-Perdomo, and Martin Hingley. "Exploring producers' motivations and challenges within a farmers' market." British Food Journal 122, no. 7 (April 6, 2020): 2089–103. http://dx.doi.org/10.1108/bfj-09-2019-0731.
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PurposeThe purpose of this study is to explore food producers' motivations and challenges whilst participating in short food supply chains (SFSCs). This paper compares findings with previous literature and investigates the topic in the context of producers' motivations.Design/methodology/approachThe paper includes a literature review concerning producers' motivations to engage in SFSCs. A case study was designed to investigate motivations underlying producers' engagement in SFSCs, as well as the challenges that they face. Semi-structured interviews were conducted in a farmers' market located in Mexico. Thematic analysis is used to identify the principal issues for producers'. Propositions based on findings are presented.FindingsFindings suggest that small, large, part-time and full-time producers are willing to engage with farmers' markets for diverse primary economic and non-economic motivations. Individual and collective challenges were also identified.Originality/valueThis research helps to explain producers' motivations and challenges within SFSCs in an under-researched context, namely a focus on producers' and in the Global South.
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Sun, Li-ping, Hui-yu Li, Xiao-ling Yi, Aime Niyonsaba, Ning-fang Wang, and Sheng-hua Jie. "Detection and Clinical Significance of Circulating Microvesicles in Severe Fever with Thrombocytopenia Syndrome." Infection International 2, no. 2 (June 1, 2013): 49–54. http://dx.doi.org/10.1515/ii-2017-0040.
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Abstract Objective Microvesicles (MV) released from blood cells play an important role in the progress of diseases. The purpose of this study is to detect circulating MV level of patients suffering from severe fever with thrombocytopenia syndrome (SFTS). Methods The plasma samples of SFTS patients and healthy controls were collected. And MV from samples were isolated and MV levels were detected quantitatively. Results The results showed that the level of the circulating MV in SFTS patients was obviously higher than that of the healthy control, with statistically significant difference. Further analysis revealed that MV level was relevant to the severity of SFTS patients, namely the higher the concentration of MV, the more severity of the disease. Linear correlation analysis showed that the circulating MV level in SFTS was correlated positively with leukocyte count (r = 0.243, P < 0.05), but no correlation with the platelet count (r = 0.193, P >0.05). Conclusions We demonstrated that there existed high level of circulating MV in SFTS patients, and the level of circulating MV had a close relationship with the severity of the disease and leukocyte count. Therefore, monitoring the level of circulating MV may provide a new indicator for predicting the prognosis of SFTS patients.
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Vasconcellos, Maria Lúcia. "Systemic functional translation studies (sfts): the theory travelling in brazilian environments." DELTA: Documentação de Estudos em Lingüística Teórica e Aplicada 25, spe (2009): 585–607. http://dx.doi.org/10.1590/s0102-44502009000300003.
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This paper presents a mapping of the Systemic Functional Translation Studies (SFTS) tradition in the Brazilian environment, from its genesis up to developments in the 2000's. While studies during the earlier period are informed by the concept of "translation as (re)textualization", more recent SFTS research can be charted along the 'cline of instantiation', translations being investigated as "instantiations-in-contexts", cross-lingual functional varieties of language, or still as sources of SFL-based language description of Brazilian Portuguese. From late 90's on, computerized corpora and corpus-based methodologies have been integrated into Brazilian SFTS, for which annotation methods for the tagging of SFL categories have been developed. The paper ends with a consideration of Brazilian SFTS against the background of international SFTS as disseminated in the 2nd HCLS.
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Rucabado-Palomar, Thais, and Mamen Cuéllar-Padilla. "Short food supply chains for local food: a difficult path." Renewable Agriculture and Food Systems 35, no. 2 (September 10, 2018): 182–91. http://dx.doi.org/10.1017/s174217051800039x.
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AbstractAgri-food globalization is having a serious adverse impact on small- and medium-sized family farms in the province of Málaga (southern Spain), 43% of which have disappeared over the last 10 years. Short food supply chains (SFSCs) are emerging as a potential option for this type of farm, but as a strategy it is apparently not being implemented strongly enough over the region as a whole. The current case study sought to explore the initiatives carried out by local producers to date in implementing SFSCs throughout the province and to examine, from the standpoint of the production sector, the constraints hindering its development and the strategies currently being adopted with a view to addressing them. The analyses carried out under local producers perspective shows us that although SFSCs are interesting for family farms, in terms of prices, economic profit and social recognition, the abilities and capacities these channels require to producers, jointly with technical, flexibility and time demands, make these channels to be not that successful and attractive. Small producers interested in SFSCs must be aware of the special importance of social linkages and the need to take care of them; as well as of the need of establishing synergies and cooperation with other producers and stakeholders, in order to facilitate the tasks associated and that not every food product suit SFSCs.
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Goretti Polito, Maria, Michelle Tiveron Passos, Danilo Euclides Fernandes, and Gianna Mastroianni-Kirsztajn. "Clinical and laboratory features that differentiate familial from sporadic focal segmental glomerulosclerosis in adolescents and adults." Journal of Rare Diseases Research & Treatment 6, no. 1 (January 1, 2021): 1–5. http://dx.doi.org/10.29245/2572-9411/2021/1.1199.
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Background: Focal segmental glomerulosclerosis (FSGS) is an important cause of end-stage kidney disease in children and adults. Although most cases are sporadic (s), familial (f) presentation is also described. The purpose of the present study was to establish clinical and laboratory profiles of fFSGS vs. primary sFSGS, contributing to the distinguishing diagnosis in clinical practice and best management, in particular when mutation analysis is not available. Methods: Demographic, clinical and laboratorial parameters were studied in 124 patients 12 years and older with FSGS, subdivided in sFSGS (n=89) and fFSGS (n=35). Results: General and clinical features were similar, as well as serum creatinine at disease presentation. Proteinuria levels were more frequently ≥ 3g/day in sFSGS (63.8%) than in fFSGS (44%, p=0.080), and serum albumin levels were < 3.0 g/dL in 45.8% and 20%, respectively (p=0.046). The groups were statistically different regarding steroid resistance, corresponding to 60% in sFSGS and 100% in fFSGS (p=0.001). Conclusions: The studied groups were clinically similar, except that proteinuria tended to be higher (nephrotic range) and serum albumin was lower in sFSGS vs. fFSGS. In addition, all treated fFSGS patients were steroid resistant. At presentation it is important to characterize if the patient has fFSGS, that will contribute to further disease management, and disease history will be the first clue for such differential diagnosis.
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Iwao, Kosho, Takeshi Kawaguchi, Masatoshi Kimura, Chihiro Iwao, Mao Rikitake, Ayako Aizawa, Yumi Kariya, et al. "Severe Fever with Thrombocytopenia Syndrome Accompanied by Invasive Pulmonary Aspergillosis: An Autopsy Case." Viruses 13, no. 6 (June 7, 2021): 1086. http://dx.doi.org/10.3390/v13061086.
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Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tickborne infectious disease in China, Korea, and Japan caused by the SFTS virus (SFTSV). SFTS has a high mortality rate due to multiorgan failure. Recently, there are several reports on SFTS patients with mycosis. Here, we report a middle-aged Japanese SFTS patient with invasive pulmonary aspergillosis (IPA) revealed by an autopsy. A 61-year-old man with hypertension working in forestry was bitten by a tick and developed fever, diarrhea, and anorexia in 2 days. On day 4, consciousness disorder was appearing, and the patient was transferred to the University of Miyazaki Hospital. A blood test showed leukocytopenia, thrombocytopenia, as well as elevated levels of alanine aminotransferase, aspartate aminotransferase, lactate dehydrogenase, and creatine kinase. The SFTSV gene was detected in serum using a reverse-transcription polymerase chain reaction. On day 5, respiratory failure appeared and progressed rapidly, and on day 7, the patient died. An autopsy was performed that revealed hemophagocytosis in the bone marrow and bleeding of several organs. IPA was observed in lung specimens. SFTSV infection may be a risk factor for developing IPA. Early diagnosis and treatment of IPA may be important in patients with SFTS.
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Chiffoleau, Yuna, and Tara Dourian. "Sustainable Food Supply Chains: Is Shortening the Answer? A Literature Review for a Research and Innovation Agenda." Sustainability 12, no. 23 (November 24, 2020): 9831. http://dx.doi.org/10.3390/su12239831.
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Short food supply chains (SFSCs) are increasingly garnering attention in food systems research, owing to their rising popularity among consumers, producers and policy-makers in the last few decades. Written with the aim to identify research gaps for the Horizon Europe research and innovation programme, this literature review provides a state of play of the definition and characterisation of SFSCs, and of their sustainability. Drawing on hypotheses about SFSC sustainability elaborated in an expert network in France, this review summarises a wide range of papers from various disciplines in the SFSC literature, written in English or French, while specifically highlighting the empirical results derived from European projects. Though the literature tends to generally agree on the social benefits of SFSCs, their economic and environmental impacts typically elicit more heterogeneous outcomes, while their health/nutrition and governance dimensions remain under-explored. Based on this review, recommendations for a future research and innovation programme are outlined, addressing the contribution of SFSCs to agrifood system transition and resilience in the current context of the Covid-19 crisis and of the Green New Deal objectives.
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Negoro, Hitoshi. "MAXI observations of long-term X-ray activities in SFXTs." Proceedings of the International Astronomical Union 14, S346 (August 2018): 202–5. http://dx.doi.org/10.1017/s1743921319001194.
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AbstractSupergiant Fast X-ray Transients (SFXTs) are of great interest not only because of their peculiar properties but also as possible progenitors of gravitational-wave objects. The all-sky X-ray monitor MAXI/GSC has detected short flares on timescales of hours and long flares on timescales of days from SFXTs. Using nine-years of MAXI/GSC data, I attempted to search periodicity of eight SFXTs of which the one-day average fluxes were below the detection limit (∼ 10 mCrab), and confirmed the orbital periods of IGR J18483–0311 and IGR J17544–2619. This demonstrates that MAXI data are useful to find periodicities of sources even if the sources are undetectable in one day.
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Huang, Xiaoxia, Jiandong Li, Aqian Li, Shiwen Wang, and Dexin Li. "Epidemiological Characteristics of Severe Fever with Thrombocytopenia Syndrome from 2010 to 2019 in Mainland China." International Journal of Environmental Research and Public Health 18, no. 6 (March 17, 2021): 3092. http://dx.doi.org/10.3390/ijerph18063092.
Full textAbstract:
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease and that is a severe threat to public health considering its high fatality and person-to-person transmission. In order to obtain an updated and deep understanding of the epidemiological characteristics of SFTS in mainland China, we used Pearson’s chi-squared test to compare the fatality rate and demographic characteristics in different groups. Data were analyzed in R3.6.1 (R Development Core Team 2018), while the visualization was performed in ArcGIS 10 (ESRI, Redlands, CA, USA), and the statistical significance was set at p < 0.05. A total of 13,824 SFTS cases involving 8899 lab-confirmed cases and 4925 probable cases were reported and included in the epidemiological analysis. Our study found that the number of SFTS cases showed an increasing trend with a small decrease in the past three years. The laboratory-confirmed rate was about 64.4%, which varied between different years and areas. Although most cases (99.3%) were distributed in 7 provinces (Henan, Shandong, Anhui, Hubei, Liaoning, Zhejiang, and Jiangsu), the regional distribution of SFTS gradually expanded from 5 provinces in 2010 to 25 provinces by 2019, especially at the town level. The SFTS cases were mainly sporadic. A total of 96.5% occurred from April to October, and 93.3% of cases were concentrated in middle-aged and elderly people (40–84 years old). Farmers were the main high-risk population. Female cases were slightly more than male cases; however, there were differences between different provinces. The mortality rate showed an increasing trend with age. Overall, the SFTS cases were mainly middle-aged and elderly farmers that sporadically distributed throughout seven provinces with a spatially expanding trend. The laboratory-confirmed rate varied in different years and provinces, which implied that the diagnosis and report criteria for SFTS should be further updated and unified in order to get a better understanding of its epidemiological characteristics and provide scientific data for SFTS control.