Dissertations / Theses on the topic 'Severity of liver damage'
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Habib, Shahid, Khalid Khan, Chiu-Hsieh Hsu, Edward Meister, Abbas Rana, and Thomas Boyer. "Differential Simultaneous Liver and Kidney Transplant Benefit Based on Severity of Liver Damage at the Time of Transplantation." ELMER PRESS INC, 2017. http://hdl.handle.net/10150/625529.
Full textZambon, Azevedo Vittoria. "Mise au point d’un nouvel outil diagnostique de l’obésité sarcopénique : relations avec la dysfonction du tissu adipeux, l’insulinorésistance et la sévérité de l’atteinte hépatique." Electronic Thesis or Diss., Sorbonne université, 2024. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2024SORUS170.pdf.
Full textSarcopenic obesity (SO) is a condition characterized by the coexistence of obesity and sarcopenia, the latter defined as a reduction in muscle mass and function. Diagnosing SO is highly complex due to the lack of universally accepted diagnostic criteria, leading to imprecise diagnoses and highly variable prevalence estimates. Given this scenario, this thesis aimed to develop an empirical diagnostic tool for SO using artificial intelligence, based on the analysis of body composition. We developed the AIM-SO score in a population of patients with overweight/obesity and tested it in two other populations: patients with severe obesity undergoing bariatric surgery (BS) and the general population of the UK Biobank. A longitudinal study with a one-year follow-up was conducted in subjects who underwent BS. We examined clinical correlations, particularly cardiometabolic and hepatic, including perioperative histological findings in the bariatric cohort. The prevalence of SO was similar across these three cohorts. SO diagnosed by the AIM-SO score was associated with multiple cardiometabolic comorbidities and more severe inflammatory and fibrosing liver damage. Despite weight loss, the metabolic benefit (remission of comorbidities) after BS was lower in patients with SO. Preliminary analyses of the UK Biobank cohort showed a significant association between SO diagnosed by the AIM-SO score and parameters of muscular functionality, particularly muscle strength. We propose this new diagnostic tool to standardize the SO diagnosis and identify patients with obesity and sarcopenia who exhibit more severe cardiometabolic and hepatic phenotype. Diagnosing SO could also inform the expected benefit of various weight loss interventions, thus contributing to personalized medical management
Fisher, D. R. "Studies on residual damage in irradiated liver." Thesis, University of Manchester, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.355903.
Full textNowak, Urszula. "Rheumatoid factor production in response to liver damage." Thesis, McGill University, 2005. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=84065.
Full textMiyachi, Yosuke. "Causes of liver steatosis influence the severity of ischemia reperfusion injury and survival after liver transplantation in rats." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/263516.
Full textMüller, Hans Christian. "Alternative strategies to reduce liver abscess incidence and severity in feedlot cattle." Thesis, Kansas State University, 2017. http://hdl.handle.net/2097/38157.
Full textDepartment of Animal Sciences and Industry
James S. Drouillard
Since the 1960’s liver abscess incidence and severity have been identified as a problem associated with feeding high concentrate finishing rations to feedlot cattle. Liver abscesses lead to decreased feedlot performance and decreased carcass value. Tylosin phosphate is a macrolide antibiotic commonly used by feedlots throughout the United States and has been shown to successfully control liver abscesses. In 2013, the FDA issued Guidance for Industry #213, which encourages reduced usage of medically important classes of antibiotics, such as macrolides, in animal feed. This will be achieved by implementing veterinary oversight of these drugs via Veterinary Feed Directives (VFD). Thus, it is of importance to find alternative strategies to reduce usage of tylosin in finishing rations to control liver abscesses. One strategy that has been suggested is increasing dietary roughage concentration. However, this isn’t a viable option as increasing dietary roughage concentration not only leads to a decline in feedlot performance, hot carcass weight, and dressing percentage, but also has an environmental impact. Available research has also indicated that increasing dietary roughage has no impact on liver abscess incidence or severity. Our research objective was therefore to identify alternative strategies to reduce liver abscess incidence. Our first trial evaluated the impact of antioxidants on liver abscess incidence and severity. Treatments consisted of a control treatment (basal diet containing 200 IU/d α-tocopherol acetate), and an antioxidant treatment (basal diet containing 2000 IU/d α-tocopherol acetate and 500 mg/d crystalline ascorbate). Treatments were randomly assigned to 390 crossbred heifers. No differences in feedlot performance were detected; however, there was a tendency for improved feed intake (P = 0.075) and feed efficiency (P = 0.066) for heifers that received the antioxidant treatment. An increased number of yield grade 3 carcasses (P = 0.03) and fewer yield grade 1 carcasses (P < 0.01) was observed in the antioxidant treatment group. No differences were detected between treatments for other carcass characteristics or liver abscess incidence and severity. Another trial evaluated intermittent tylosin feeding and its impact on liver abscess incidence and antimicrobial resistant Enterococcus spp. when compared to continuous tylosin feeding. One of 3 treatments were randomly assigned to 312 crossbred steers: negative control (no tylosin fed throughout the feeding period); positive control (tylosin fed throughout the feeding period); or intermittent treatment (tylosin fed intermittently throughout the feeding period: 1week on, 2 weeks off). Fecal samples were collected on day 0, 20, and 118 to characterize antimicrobial resistant Enterococcus spp. By design, the intermittent treatment consumed 60% less tylosin than the positive control group. No differences were detected between treatments for feedlot performance. Liver abscess incidence was greatest for the negative control, and least for the positive control and intermittent treatments, with no difference being detected between the latter two treatments (P = 0.716). Antimicrobial resistance was unaffected by treatment, but was affected by sampling time. We concluded that supplementing antioxidants is not a viable option to reduce liver abscess incidence and severity, and that tylosin usage can be decreased without adversely affecting performance or liver abscess incidence.
Haydon, Geoffrey H. "The severity and activity of liver disease in chronic hepatitis C infection." Thesis, University of Edinburgh, 1999. http://hdl.handle.net/1842/28213.
Full textKistler, Kristin David. "Nonalcoholic fatty liver disease quality of life, exercise intensity and histological severity /." Diss., [La Jolla] : [San Diego] : University of California, San Diego ; San Diego State University, 2009. http://wwwlib.umi.com/cr/ucsd/fullcit?p3359523.
Full textTitle from first page of PDF file (viewed July 21, 2009). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.
Висоцький, Ігор Юрійович, Игорь Юрьевич Высоцкий, Ihor Yuriiovych Vysotskyi, Алла Анатоліївна Качанова, Алла Анатольевна Качанова, Alla Anatoliivna Kachanova, V. I. Vysotsky, Ya V. Serduk, and K. R. Denisova. "Chronopharmacological peculiaries of antioxidants action in toxic liver damage." Thesis, Sumy State University, 2015. http://essuir.sumdu.edu.ua/handle/123456789/41261.
Full textHolland, Michael J. "Measuring Disease Damage and its Severity in Childhood-Onset Systemic Lupus Erythematosus." University of Cincinnati / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1527606864223975.
Full textNalapareddy, Padmavathi Devi [Verfasser]. "Role of bid in liver injury following BDL and CCl4-induced liver damage / Padmavathi Devi Nalapareddy." Hannover : Technische Informationsbibliothek und Universitätsbibliothek Hannover, 2010. http://d-nb.info/1004974523/34.
Full textSoare, Catalina P. "Characterization of Liver Damage Mechanisms Induced by Hepatitis C Virus." Thèse, Université d'Ottawa / University of Ottawa, 2011. http://hdl.handle.net/10393/20343.
Full textPereira, Pedro Miguel Miranda Sousa Gonçalves. "Severity and extent of tissue damage in human and experimental temporal lobe epilepsy." Doctoral thesis, Instituto de Ciências Biomédicas Abel Salazar, 2007. http://hdl.handle.net/10216/7259.
Full textPereira, Pedro Miguel Miranda Sousa Gonçalves. "Severity and extent of tissue damage in human and experimental temporal lobe epilepsy." Tese, Instituto de Ciências Biomédicas Abel Salazar, 2007. http://hdl.handle.net/10216/7259.
Full textKnight, Trudy Lynn. "The molecular basis of halothane-induced hepatotoxicity." Thesis, Imperial College London, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321782.
Full textPesce, Paola. "Non Alcoholic Fatty Liver Disease: non invasive markers of severity and new experimental treatments." Doctoral thesis, Università degli studi di Padova, 2018. http://hdl.handle.net/11577/3422225.
Full textMarker, Alison Jean. "Mechanisms of regulation of liver metabolism and growth." Thesis, King's College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287759.
Full textUpadhyaya, Sneha. "Development of an Improved and Internally-Consistent Framework for Evaluating Liquefaction Damage Potential." Diss., Virginia Tech, 2019. http://hdl.handle.net/10919/95941.
Full textDoctor of Philosophy
Soil liquefaction continues to be one of the leading causes of ground failure during earthquakes, resulting in significant damage to infrastructure around the world (e.g., the 2010-2011 Canterbury earthquake sequence in New Zealand, 2010 Maule earthquake in Chile, and the 2011 Tohoku earthquake in Japan). Soil liquefaction refers to a condition wherein saturated sandy soil loses strength as a result of earthquake shaking. Surface manifestations of liquefaction include features that are visible at the ground surface such as sand boils, ejecta, cracks, and settlement. The severity of manifestation is often used as a proxy for damage potential of liquefaction. The overarching objective of this dissertation is to develop improved models for predicting triggering (i.e., occurrence) and surface manifestation of liquefaction such that the impacts of liquefaction on the natural and built environment can be minimized. Towards this end, this dissertation makes the following main contributions: (1) development of an approach for selecting an appropriate factor of safety (FS) against liquefaction for decision making based on project-specific consequences, or costs of mispredicting liquefaction; (2) development of an approach that allows better interpretations of predictions of manifestation severity made by the existing models in profiles having high fines-content, high plasticity soil strata (e.g., clayey and silty soils), given that the models perform poorly in such conditions; (3) development of a new model for predicting the severity of manifestation that more fully accounts for factors controlling manifestation; and (4) development of a framework for predicting liquefaction triggering and surface manifestation such that the distinct factors influential to each phenomenon are handled more rationally and consistently.
Anwar, Khurshid. "Role of apoptosis (programmed cell death) in acute liver failure." Thesis, University of Surrey, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.370058.
Full textKulachek, Y. V., F. G. Kulachek, and V. T. Kulachek. "Estimation of severity of the early period of traumatic disease in victims with liver injury." Thesis, БДМУ, 2017. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/16910.
Full textYasmin, Mahmuda. "Molecular biology of fulminant hepatitis B viruses." Thesis, University of Glasgow, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.360121.
Full textRamirez, Javier. "Identification of sites of ethanol-derived protein adducts involved in liver damage." Tallahassee, Fla. : Florida State University, 2010. http://purl.fcla.edu/fsu/lib/digcoll/undergraduate/honors-theses/2181934.
Full textAdvisor: Dr. Mark Kearley, Florida State University, College of Arts and Sciences, Dept. of Chemistry and Biochemistry. Includes bibliographical references.
Cass, Stacie Ann. "The effects of sexual harassment severity and organizational policy and response on juror damage awards." FIU Digital Commons, 2002. http://digitalcommons.fiu.edu/etd/2068.
Full textGhallab, Ahmed [Verfasser]. "Spatial-temporal modelling of liver damage as well as regeneration and its influence on metabolic liver function / Ahmed Mohammed Ghallab." Gießen : Universitätsbibliothek, 2013. http://nbn-resolving.de/urn:nbn:de:hebis:26-opus-98761.
Full textGhallab, Ahmed Mohammed [Verfasser]. "Spatial-temporal modelling of liver damage as well as regeneration and its influence on metabolic liver function / Ahmed Mohammed Ghallab." Gießen : Universitätsbibliothek, 2013. http://d-nb.info/1065320353/34.
Full textGewiese, Jessica [Verfasser]. "Role of IL-6 Transsignaling in acute CCl4-induced liver damage / Jessica Gewiese." Kiel : Universitätsbibliothek Kiel, 2010. http://d-nb.info/1019982640/34.
Full textYang, Sitian, and 楊斯恬. "Novel role of drug-induced non homologous end joining factor 1 in the chemoresistance of hepatocellular carcinoma." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2015. http://hdl.handle.net/10722/209505.
Full textSuh, Jihee. "Evaluation of Association of MicroRNA-122 with Histological Severity of Recurrent HCV Infection in Liver Transplant Recipients." VCU Scholars Compass, 2009. http://scholarscompass.vcu.edu/etd/1890.
Full textSparks, Jessica L. "Biomechanics of blunt liver injury relating internal pressure to injury severity and developing a constitutive model of stress-strain behavior /." Columbus, Ohio : Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1185909955.
Full textBuitrago, Molina Laura Elisa [Verfasser]. "mTOR inhibition impairs proliferation of hepatocytes with DNA damage during chronic liver injury thereby delaying liver tumor development / Laura Elisa Buitrago Molina." Hannover : Technische Informationsbibliothek und Universitätsbibliothek Hannover, 2010. http://d-nb.info/1009414127/34.
Full textArp, Melanie K. "The frequency and severity of problem behaviors among individuals with autism, traumatic brain injury, and mental retardation from the Utah DSPD dataset /." Diss., CLICK HERE for online access, 2006. http://contentdm.lib.byu.edu/ETD/image/etd1050.pdf.
Full textCowan, Matthew Lawson. "The application of proteomics to the discovery of biomarkers of diseases severity and prognosis in chronic liver disease." Thesis, St George's, University of London, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.568724.
Full textКононенко, Микола Григорович, Николай Григорьевич Кононенко, Mykola Hryhorovych Kononenko, and І. М. Лукавенко. "Пошкодження печінки." Thesis, Видавництво СумДУ, 2004. http://essuir.sumdu.edu.ua/handle/123456789/9454.
Full textКононенко, Микола Григорович, Николай Григорьевич Кононенко, Mykola Hryhorovych Kononenko, Андрій Олександрович Бойчунь, and Andrii Oleksandrovych Boichun. "Актуальні питання артеріального гемостазу при пошкодженні печінки." Thesis, Видавництво СумДУ, 2009. http://essuir.sumdu.edu.ua/handle/123456789/6696.
Full textЛішневська, Анастасія Геннадіївна, Анастасия Геннадьевна Лишневская, and Anastasiia Hennadiivna Lishnevska. "Degree of severity of laboratory syndromes in patients whith chronic viral hepatitis C." Thesis, Sumy State University, 2018. http://essuir.sumdu.edu.ua/handle/123456789/70787.
Full textВ мире около 71 миллиона человек имеют инфекцию ВГС. Примерно половина смертельных случаев вызвана циррозом и гепатоцеллюлярной карциномой.
In the world there areabout 71 million people who have an HCV infection. Approximately half of the fatal cases are cused by cirrhosis and hepatocellular carcinoma.
Lee, Matthew L., and Jonathan M. Peterson. "CTRP3 Protects Liver Cells From Alcohol-Induced Damage, But Not Through Enhanced Akt Signaling Type." Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/etsu-works/70.
Full textSmart, Kevin Arthur. "The mechanism by which hyperammonaemia may cause hepatic encephalopathy." Thesis, King's College London (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267312.
Full textVilfranc, Chrystelle L. "Elucidating the Role of BRUCE in Chronic Liver Disease Pathogenesis." University of Cincinnati / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1617107353008576.
Full textFinnberg, Niklas. "The attenuation of the P53 response to DNA damage in rodent liver preneoplastic enzyme-altered foci /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-462-3.
Full textYe, Xingshen. "Studies on effects of coptis extract and berberine against carbon tetrachloride-induced liver damage in rats." View the Table of Contents & Abstract, 2007. http://sunzi.lib.hku.hk/hkuto/record/B38718832.
Full textGhafoory, Shahrouz [Verfasser], and Stefan [Akademischer Betreuer] Wölfl. "Gene expression recovery during an acute toxic damage in the liver / Shahrouz Ghafoory ; Betreuer: Stefan Wölfl." Heidelberg : Universitätsbibliothek Heidelberg, 2015. http://d-nb.info/118039688X/34.
Full textYe, Xingshen, and 叶星沈. "Studies on effects of coptis extract and berberine against carbon tetrachloride-induced liver damage in rats." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B38755208.
Full textGibhard, Liezl. "Ozone autohaemotherapy protects against Ketamine hydrochloride® induced liver and muscle damage in baboons / L. Gibhard." Thesis, North-West University, 2007. http://hdl.handle.net/10394/759.
Full textThesis (M.Sc. (Biochemistry))--North-West University, Potchefstroom Campus, 2008.
Kamimura, Ryo. "Comparative study of transplantation of hepatocytes at various differentiation stages into mice with lethal liver damage." Kyoto University, 2012. http://hdl.handle.net/2433/157436.
Full textGao, Yong. "Noninvasive monitoringn of CCl4 induced acute and chronic liver damage in rat by single quantum and triple quantum filtered 23Na magnetic resonance imaging." Connect to resource online, 2008. http://hdl.handle.net/1805/2045.
Full textTitle from screen (viewed on January 26, 2010). Department of Cellular & Integrative Physiology, Indiana University-Purdue University Indianapolis (IUPUI). Advisor(s): Navin Bansal, Andriy M. Babsky, Stephen A. Kempson, David P. Basile. Includes vitae. Includes bibliographical references (leaves 33-36).
Wali, Mohamed Hatem Fathi El-Saied. "Natural history, factors affecting severity and progression rate of hepatitis C virus (HCV) infection in liver transplanted and non-transplanted patients." Thesis, University of Birmingham, 2002. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269215.
Full textZohora, Fatematuz. "Evaluation of material crack using acoustic emission technique." Thesis, Queensland University of Technology, 2016. https://eprints.qut.edu.au/94663/1/Fatematuz_Zohora_Thesis.pdf.
Full textBilling, S. E. "An evaluation of different methods of measuring lipid peroxidation and their application to the assessment of liver cell damage induced by certain hepatoxic agents." Thesis, Brunel University, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.383745.
Full textRose, David Harry. "A Cumulative Damage Approach to Modeling Atmospheric Corrosion of Steel." University of Dayton / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=dayton1417085212.
Full textAmin, Alla Mohammed Hussain. "Cold ischaemia and reperfusion injury in liver : the potential for damage to cellular DNA in the rat model." Thesis, University College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248455.
Full text