Academic literature on the topic 'Sesbania grandiflora plants'
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Journal articles on the topic "Sesbania grandiflora plants"
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Shaikh, Shoheb Shakil. "Pharmacognostical, phytochemical standardization and anticonvulsant activity study of sesbania grandiflora flowers." International Journal of Pharmaceutical Chemistry and Analysis 9, no. 2 (August 15, 2022): 99–104. http://dx.doi.org/10.18231/j.ijpca.2022.016.
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In the India there is a good biodiversity in plants. Plants based medicinal products used as integrated part of treatment on most of traditional systems of medicines. Sesbania grandiflora is a plant which used traditionally for many medicinal used which belongs in family Fabaceae. Present study was about investigated the Physicochemical and Phytochemical studies on selected plant such as Sesbania grandiflora. For the study Soxhlet apparatus was used for extraction of plant materials with using water, ethanol and chloroform as extractive solvents. Standard chemicals and methods were used for the qualitative determination of plant S. grandiflora flowers extract. The study investigation was followed to determine the presence of chemical compound in flowers part of plant as well as to investigate the quality of drug. Result found that the different flower extract may presence of alkaloids, steroids, tannins, sterols, flavonoid etc. The pentylenetetrazol (PTZ) induced seizure model was used for testing anticonvulsant activity of ethanolic, aqueous and chloroform extracts(100mg/kg) of Sesbania grandiflora flowers. The extracts significantly (*p < 0.01) reduced the duration of convulsion and delay onset of seizure. The study results that Sesbania grandiflora flowers has anticonvulsant activity.
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Handayani, Putu Novi, Ni Made Ayudia Shanty, and Ni Kadek Saras Dwi Guna. "Antioxidant Potential of White Turi Stem (Sesbania grandiflora) in Reducing Malondialdehyde (MDA) and Blood Glucose Levels in Type 2 Diabetes Mellitus Model Mice." International Journal of Research and Review 9, no. 6 (July 1, 2022): 520–26. http://dx.doi.org/10.52403/ijrr.20220655.
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Type 2 Diabetes Mellitus triggers hyperglycaemia conditions resulting in oxidative stress which is characterized by increased production of Reactive Oxygen Species (ROS) inducing in cell damage, resulting in lipid peroxidation which decomposes in the blood into Malondialdehyde (MDA). The use of natural antioxidants is believed to be safer and more effective in the long term. One of the plants that has a strong antioxidant content and activity is the White Turi Plant (Sesbania grandiflora). This study aimed to examine the antioxidant activity of white turi (Sesbania grandiflora) stem extract in reducing MDA and blood sugar levels in Type 2 DM model mice. A quasi-experimental method with an in vivo design was used in this study. A sample of 30 hyperglycaemic mice was divided into 5 groups: group K- was given aquadest and standard feed, group K+ was given glibenclamide 0.013 mg/20gBW, group I was given extract at a dose of 2.8 mg/20gBW, group II was given extract at a dose of 5, 6 mg/20gBW and group III was given extract at a dose of 11.2 mg/20gBW. At the end of the study, blood glucose and MDA levels will be measured as a biomarker of oxidative stress. Repeated measurement Anova and One-way Anova test was used in this study, it was found that white turi (Sesbania grandiflora) stem extract at a dose of 2.8 mg/gBW had an effect on decreasing blood glucose levels in mice. Moreover, based on the results of the MDA level test, it showed that there was an effect of white turi stem extract on reducing MDA levels in the blood of mice. In conclusion, white turi stem (Sesbania grandiflora) has the potential to reduce MDA and blood sugar levels in Type-2 DM model mice. Keywords: [White Turi Stem (Sesbania grandiflora), Malondialdehyde, Blood Glucose, Reactive Oxygen Species, Diabetes Mellitus Type2] .
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Rohmah, Jamilatur, Ida Agustini Saidi, Luthfiyah Rofidah, Fia Novitasari, and Frida Amelia Margareta. "Phytochemical Screening of White Turi (Sesbania grandiflora (L.) Pers.) Leaves Extract in Various Extraction Methods." Medicra (Journal of Medical Laboratory Science/Technology) 4, no. 1 (August 2, 2021): 22–29. http://dx.doi.org/10.21070/medicra.v4i1.1395.
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One of the Fabaceae family that has potential as medicinal plant is the white Turi plant (Sesbania grandiflora (L.) Pers.).The purpose of this study was to determine the content of secondary metabolites which can be extracted using a various extraction methods.The extraction method used are digestion, percolation, reflux, soxhlet, infusion, and decoction extraction. The Turi plants used come from Mojosari, Mojokerto.The results of the initial phytochemical screening of white Turi leaf extract (Sesbania grandiflora (L.) Pers.) Were extracts in six extraction methods containing alkaloids, saponins and tannins.In extracts using the digestion, soxhlet, and reflux method containing steroids.Meanwhile, the four extracts from the digestion, percolation, soxhlet, and reflux methods contain phenolic.And the infusion and decoction method extracts containing flavonoids and triterpenoids. The similarity of the phytochemical test results for each extract but with different intensity results.
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K, SURENDRAGOPAI, and SHIVAPPASHETTY K. "GREEN MANURING FOR RICE WITH RHIZOBIUM INOCULATED Sesbania grandiflora." Madras Agricultural Journal 83, April (1996): 249–50. http://dx.doi.org/10.29321/maj.10.a01016.
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The Rhizobium isolates were obtained from root nodules of Sesbania grandiflora (L.) grown in different soil samples. In Leonard jar experiment, the plants inoculated with the isolate. SG-5 gave maximum dry weight (1 g/plant), nodule number (47 per pl int) and total nitrogen content (51.80 mg/plant). Similarly pot culture experiment also revealed that plant inoculated with SG-5 isolate gave maximum dry weight (1.51 g/plant) and total nitrogen content (43.34 mg/plant). The response of rice crop to the incorporation of inoculated green manure was encouraging with respect to nitrogen content, phosphorus content and grain yield.
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Ate, Vianros Ana, Yanti Daud, and Alan Ch Sabuna. "Pemanfaatan Tumbuhan Dalam Proses Pewarnaan Kain Tenun Ikat Di Desa Harona Kalla Kecamatan Laboya Barat Kabupaten Sumba Barat." Indigenous Biologi : Jurnal Pendidikan dan Sains Biologi 3, no. 1 (January 5, 2021): 14–22. http://dx.doi.org/10.33323/indigenous.v3i1.75.
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This study aims to determine the types of natural dye plants, organs or plant parts used in the process of coloring woven cloth, and the processing of plants to produce colors as dyes of woven cloth, colors produced from plants dyed woven cloth dyes in Harona Kalla Village, West Laboya sub-district, West Sumba Regency. The method used is a qualitative method with semi-structural observation and interview techniques that refer to the list of questions that have been prepared. Based on the results of research in Harona Kalla Village, west Laboya sub-district, West Sumba Regency, three types of natural coloring plants were found, namely turi leaves (Sesbania grandiflora), turmeric rhizome (Curcuma domestica L), mahogany (Swietenia mahagoni L). In addition to coloring plants there are plants that are used as additives in coloring namely fence kedondong (Lannae nigritana), baiduri (Calotropis gigantea), betel lime and iron rust / vinegar. The organs in the coloring process are bark, rhizome and leaves. And the processing of plant organs is done pounding and boiling. The purpose of adding lime is to lock the color so that it does not fade easily. Based on the results of the study, the colors produced from plants in the village of Harona Kalla are turi leaves (Sesbania grandiflora) which are pounded and produce a green color. Turmeric (Curcuma domestica L) which is pounded and boiled produces yellow, mahogany bark (Swietenia mahagoni L) which is boiled produces a black color. The conclusion of this research is that it is necessary to design efforts to cultivate color-producing plants which are non-wood forest products to support the sustainable industry in Harona Kalla Village, for the cultivation of species of color-producing plants.
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Nizaar, Muhammad, and Haifaturrahmah Haifaturrahmah. "IDENTIFIKASI TANAMAN SAYURAN LOKAL DI DESA SENARU SEBAGAI SUMBER BELAJAR BIOLOGI." Paedagoria | FKIP UMMat 8, no. 1 (April 30, 2017): 26. http://dx.doi.org/10.31764/paedagoria.v8i1.162.
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Abstrak: Hasil penelitian ini bermanfaat sebagai sumber belajar bagi siswa SMA/MA. Metode penelitian yang digunakan yaitu eksplorasi lapangan dalam bentuk survey di Desa Senaru. Data tanaman sayuran yang diperoleh kemudian dianalisis menggunakan teknik determinasi pencocokkan dengan literatur untuk kemudian dijadikan sumber belajar dengan urutan; nama Indonesia, nama lokal (Senaru), gambar/foto, deskripsi umum tanaman, deskripsi pertumbuhan dan perkembangan, dan bagian tanaman yang dikonsumsi. Berdasarkan hasil penelitian diperoleh berbagai jenis tanaman sayur yaitu pakis (Diplazium esculentum), terung (Solanum melongena), tomat (Solanum lycopersicum), kelor (Moringa olieifera), turi (Sesbania grandiflora), komak (Dilochos lablab L.), kacang panjang (Vigna sinensis), pisang kepok (Musa acuminata), kecipir (Psophocarpus tetragonolobus), kacang gude (Cajanus cajan), katuk (Saoropus androgynus), dan wortel (Daucus carota L.). Abstract: The result of this study is useful for high school students. The research method used is field exploration in the form of survey in Senaru Village. Vegetable plants data were obtained and analyzed by using a matching determination technique with literature then it will be used as a source of learning in sequence; Indonesia’s name, local name (Senaru), picture /photo, general description of plant, description of growth and development, and part of plant consumed. Based on the result of research, there are various types of vegetable plants, namely fern (Diplazium esculentum), eggplant (Solanum melongena), tomatoes (Solanum lycopersicum), kelor (Moringa olieifera), turi (Sesbania grandiflora), komak (Dilochos lablab L.), Vigna sinensis), bananas (Musa acuminata), winged bean (Psophocarpus tetragonolobus), gude bean (Cajanus cajan), katuk (Saoropus androgynus), and carrot (Daucus carota L).
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Ibrahim, Kadhim M., and Shaimaa A. Yousir. "In vivo and in vitro studies on heavy metal tolerance in Sesbania grandiflora L." Journal of Biotechnology Research Center 3, no. 2 (June 1, 2009): 48–64. http://dx.doi.org/10.24126/jobrc.2009.3.2.67.
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Several experiments were carried out to study heavy metal tolerance in tissue cultures or whole plants of S. grandiflora., Callus was induced and maintained on modified Murashige and Skoog, 1962 medium (MS) supplemented with (0.5)mg/l benzyl adenine and (2)mg/l 2,4-phenoxy acetic acid . Heavy metals (Cd, Co, Cu, Cr or Zn) were added to the culture medium at different concentrations as contamination agents. In order to asses the effect of these heavy metals on seed germination; seeds were sown in soil contaminated with different concentrations of heavy metals for 3 weeks. Atomic Absorption Spectrophotometer was used for analysis of samples taken from whole plants and callus cultures. Results showed that callus fresh weight decreased with increasing heavy metal concentration in cultural medium. Germination percentages and plant heights increased over time. However, a reduction occurred in these parameters with increasing heavy metal levels. Percentages of metals accumulated in calli were (0.001, 0.011, 0.012 and 0.013%) at (0.0, 0.05, 0.075 and 0.1)mg/l Cd respectively; (0.001, 0.008, 0.016 and 0.006%) at (0.0, 0.1, 0.25 and 0.5)mg/l Co respectively; (0.001, 0.020, 0.034 and 0.015%) at (0.0, 0.075, 0.2 and 0.5)mg/l Cu respectively; (0.001, 0.013, 0.012 and 0.010%) at (0.0, 0.25, 0.4 and 0.5)mg/l Cr respectively and (0.027, 0.051, 0.059 and 0.056%) at (0.0 , 0.75, 1.0 and 1.5)mg/l Zn respectively. Percentages of metals accumulated in whole plants were (0.08, 0.55, 1.11, 0.83 and 0.44%) at (0.0, 1.0, 2.0, 3.0 and 4.0)mg/Kg soil Cd respectively; (0.11, 0.22, 0.55, 0.47 and 0.44%) at (0.0, 15.0, 30.0 45.0 and 60.0)mg/Kg soil Co respectively; (0.01, 0.10, 0.57, 0.58 and 0.72%) at (0.0, 25.0, 50.0, 75.0 and 100.0)mg/Kg soil Cu respectively. (0.08, 0.80, 1.28, 1.31 and 0.88%) at (0.0, 25.0, 50.0, 75.0 and 100.0)mg/Kg soil Cr respectively and (0.06, 1.11, 1.20, 1.83 and 2.22%) at (0.0, 100.0, 200.0, 300.0 and 400.0)mg/Kg soil Zn respectively.
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Veasey, Elisabeth Ann, Marta Organo Negrão, Paulo Sodero Martins, and Gerhard Bandel. "EARLY GROWTH AND SEEDLING MORPHOLOGY OF SPECIES OF Sesbania Scop. (Leguminosae, robinieae)." Scientia Agricola 56, no. 2 (1999): 329–35. http://dx.doi.org/10.1590/s0103-90161999000200011.
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The objective of this study was to characterize 17 accessions of Sesbania, representing S. exasperata, S. grandiflora, S. sesban, S. tetraptera and S. virgata at the seedling stage, and to evaluate the initial development during the first two months after planting. The trial was conducted in a greenhouse in a randomized block design, with 4 replications and 5 plants per plot. The traits recorded were: plant height (PH), from four observations at 15-day intervals, at 17, 32, 47 and 62 days after planting; length of hypocotyl (LH) and epicotyl (LEP); length (LE1) and width (WE1) of the first eophyll; and number of leaflet pairs of the second metaphyll (NLP), evaluated 17 days after planting. Univariate analyses of variance were performed, estimating the genetic parameters: coefficient of genotypic determination (b) and of genetic variation (CVg). Cluster analysis was also obtained, using the average Euclidean distance and Unweighted pair group method of arithmetic average (UPGMA) method. At 17 days after planting, S. exasperata presented the highest PH, followed by S. virgata. At 62 days after planting, S. sesban registered the highest PH. Length of hypocotyl displayed inter but not intraspecific variation. The characters LEP, LE1, WE1 and NLP showed both inter and intraspecific variation. Cluster analysis indicated the existence of 7 groups, separating the species and revealing intraspecific variation as well. The occurrence in low frequencies of two unifoliolate opposite eophylls for some species was observed, as well as bi- or trifoliolate first eophylls for one of the S. sesban accessions. These informations are basic for the selection of traits to be utilized for characterization and differentiation of Sesbania germplasm at the juvenile phase.
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Santos, Larissa Bezerra dos, Juliana Kátia Souza, Barbara Papassoni, Dyego Gonçalves Lino Borges, Geraldo Alves Damasceno Junior, Jeana Mara Escher de Souza, Carlos Alexandre Carollo, and Fernando de Almeida Borges. "Efficacy of extracts from plants of the Brazilian Pantanal against Rhipicephalus (Boophilus)microplus." Revista Brasileira de Parasitologia Veterinária 22, no. 4 (December 2013): 532–38. http://dx.doi.org/10.1590/s1984-29612013000400013.
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This research evaluated the in vitro acaricidal activity of extracts from 21 plant species from the Pantanal of Mato Grosso do Sul. During stage I, a larval immersion test was performed using three extract concentrations (5%, 20%, and 40%). During stage II, we used only plants that showed over 95% efficiency at the 40% concentration in stage I in an amount sufficient for the adult immersion test. Aeschynomene denticulata, Angelonia hirta, Aspilia latissima, Caperonia castaneifolia, Centratherum punctatum, Crotalaria micans, Diodia kuntzei, Echinodorus paniculatus, Hyptis mutabilis, Lantana canescens, Melanthera latifolia, Ocotea diospyrifolia, Richardia grandiflora, Sebastiana hispida, Tocoyena formosa, Zanthoxylum rigidum, and Sesbania virgata (fruit extract) showed acaricidal activity against the larval stage ofRhipicephalus (Boophilus)microplus higher than 95% at a 40% (w/v) concentration, while Hippocratea volubilis and Randia armatashowed moderate efficacy and Croton glandulosus andSenna obtusifolia had no effect. The M. latifolia, A. hirta, R. grandiflora, and A. latissima raw extracts were evaluated for their activity against adults, and only A. hirta showed an efficacy close to 90%. Eighteen extracts had an efficacy of up to 95% against larvae at a 40% concentration, seven extracts were effective at 20%, and only one (Sebastiana hispida) was effective at a 5% concentration.
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Ginting, N. A., N. Ginting, I. Sembiring, and S. Sinulingga. "Effect of Eco Enzymes Dilution on the Growth of Turi Plant (Sesbania grandiflora)." Jurnal Peternakan Integratif 9, no. 1 (July 2, 2021): 29–35. http://dx.doi.org/10.32734/jpi.v9i1.6490.
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Eco Enzymes (EE) is one of the products of fermentation that comes from fruits and vegetables wastes. Enzymes and organic acid in Eco Enzymes has a positif effect on plant growth. This study aims to investigate dilution of Eco Enzymes and its application to improve the growth of Turi plants. This research used the completely randomized design method (CRD). The treatments consisted of P1 (1:300), P2 (1:200), dan P3 (1:100), and there were 5 replications. Parameters were plant height, stem diameter, number of branches, number of leaves and leaf width. The results of this research were that 1:100 dilution treatment had significant effect (p<0,05) on the the parameters of plant height, stem diameter, number of leaves and leaf width. However there was no significant effect on the number of branches. The best response to Eco Enzymes was 1: 100 dilution.
Dissertations / Theses on the topic "Sesbania grandiflora plants"
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Felipe, Rafaella Teles Arantes. "Crescimento e respostas antioxidativas em espécies leguminosas submetidas ao arsênio." Universidade Federal de Viçosa, 2007. http://locus.ufv.br/handle/123456789/4357.
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The arsenic (As) influence on the relative growth rate (TCR) and on the antioxidant system of four leguminous species: Leucocephala leucocephala, Sesbania grandiflora (woody), Cajanus cajan and Crotalaria spectabilis (shrub), it was evaluated, as well as, the accumulation of this element for these species. After the exhibition of these species to the As, in nutritious solution, they were appraised TCR and the enzymatic activity of the enzymes: superoxide dismutase (SOD), catalase (CAT), peroxidase (POX), ascorbate peroxidase (APX) and glutathione reductase (GR) and the accumulation of As for the same ones. Of the woody species, S. grandiflora showed minor influences of the As on TCR, besides presenting larger accumulation of this element than L. leucocephala. The largest tolerance presented by S. grandiflora can be related to efficient of the antioxidant system of the same. S. grandiflora, when cultivated in nutritious solution without addition of As, it presented the largest activities of the enzymes SOD, CAT, POX and GR than L. leucocephala. In the presence of As, S. grandiflora presented increment in the activity of SOD, of CAT and of POX and, L. leucocephala presented increment in the activity of SOD and of GR. Of the shrub species, C. spectabilis introduced minor influences of the As on TCR, same presenting larger concentration of this element, that C. cajan. The largest tolerance presented by C. spectabilis to the As, it should be related to the efficient antioxidant system presented by this species. C. spectabilis, when cultivated in solution containing As, it presented increment in the activity of the enzymes SOD, CAT, POX and APX, while C. cajan presented reduction in the activity of these same enzymes. In spite of other studies they be necessary to know better the mechanisms of tolerance to the As, S. grandiflora (woody) and C. spectabilis (shrub) they seem to have larger potentials for use in revegetation programs of polluted areas with As.
A influência do As sobre a taxa de crescimento relativo (TCR) e sobre o sistema antioxidante de quatro espécies vegetais leguminosas: Leucaena leucocephala e Sesbania grandiflora (arbóreas) e Cajanus cajan e Crotalaria spectabilis (arbustivas), foi avaliada, assim como, o acúmulo deste elemento por estas espécies. Após a exposição destas espécies ao As, em solução nutritiva, foram avaliadas a TCR e a atividade enzimática das enzimas: dismutase do superóxido (SOD), da catalase (CAT), da peroxidase (POX), da peroxidase do ascorbato (APX) e da redutase da glutationa (GR) e o acúmulo de As pelas mesmas. Das espécies arbóreas, S. grandiflora apresentou menor influencia do As sobre sua TCR, além de apresentar maior acúmulo deste elemento do que L. leucocephala. A maior tolerância apresentada por S. grandiflora pode estar relacionada às repostas do sistema antioxidante da mesma. S. grandiflora, quando cultivada em solução nutritiva sem adição de As, apresentou as maiores atividades das enzimas SOD, CAT, POX e GR do que L. leucocephala. Na presença de As, S. grandiflora apresentou incremento na atividade da SOD, da CAT e da POX e, L. leucocephala apresentou incremento na atividade da SOD e da GR. Das espécies arbustivas, C. spectabilis apresentou menor influencia do As sobre sua TCR, mesmo apresentando maior concentração deste elemento, do que C. cajan. A maior tolerância apresentada por C. spectabilis ao As, deve estar relacionada ao eficiente sistema antioxidante apresentado por esta espécie. C. spectabilis, quando cultivada em solução contendo As, apresentou incremento na atividade das enzimas SOD, CAT, POX e APX, enquanto que C. cajan apresentou redução na atividade destas mesmas enzimas. Apesar de outros estudos serem necessários para conhecer melhor os mecanismos de tolerância ao As, S. grandiflora (arbórea) e C. spectabilis (arbustiva) parecem ter maiores potenciais para utilização em programas de revegetação de áreas contaminadas com As.
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Bakshi, Arindam. "Mechanistic insights into the replication of Sesbania mosaic virus." Thesis, 2018. https://etd.iisc.ac.in/handle/2005/5266.
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The present thesis deals with the mechanism of replication of Sesbania mosaic virus (SeMV), which belongs to the genus sobemoviruses. Sobemoviruses are single stranded positive sense RNA viruses which infect both mono and dicotyledonous plants. SeMV, originally isolated from the farmer’s fields in Tirupati, Andhra Pradesh, India infects Sesbania grandiflora plants that belong to the Fabaceae family. The SeMV genome is 4147 nucleotides (nt) long and encodes for three overlapping open reading frames (ORF). ORF 1 codes for the MP which is involved in cell to cell movement of the virus. The ORF3 encoded CP is translated via a subgenomic RNA synthesized during the viral replication. The CP assembles into icosahedral T=3 capsids composed of 180 chemically identical subunits which are arranged within 12 pentamers and 20 hexamers. In addition to encapsidation of the progeny genome, the CP was also shown to interact with MP and could therefore be involved in long distance movement. The central ORF 2 encodes for two polyproteins 2a and 2ab via ribosomal -1 frame-shifting mechanism. The polyprotein processing studies have established four cleavage sites within polyprotein 2a and three cleavage sites in polyprotein 2ab. The domain arrangement of polyprotein 2a is membrane anchor (MA)-Protease-VPg-p10-p8 while that of 2ab is MA-Protease VPg-RdRp. The N-terminal part of both these polyproteins codes for the viral protease which falls in the category of eukaryotic serine protease and has the ability to cleave the polyproteins both in cis as well as in trans. The C terminal domain of the polyprotein 2ab represents the viral RdRp which is the key catalytic component in the viral replication
Book chapters on the topic "Sesbania grandiflora plants"
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Lim, T. K. "Sesbania grandiflora." In Edible Medicinal And Non-Medicinal Plants, 889–902. Dordrecht: Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-7395-0_72.
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Khare, C. P. "Sesbania grandiflora (L.) Poir." In Indian Medicinal Plants, 1. New York, NY: Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-70638-2_1486.
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Vinothini, Krishnamoorthy, Masilamani Sri Devi, Sudharshan Sekar, Blassan P. George, Heidi Abrahamse, Bettine van Vuuren, and Arjun Pandian. "In Vitro Plant Regeneration, Comparative Biochemical and Antioxidant Potential of Calli and Seeds of Sesbania grandiflora (L.) Poiret." In Medicinal Plants, 355–78. Boca Raton : Taylor & Francis, 2018. | “A CRC title, part of the Taylor & Francis imprint, a member of the Taylor & Francis Group, the academic division of T&F Informa plc.”: CRC Press, 2018. http://dx.doi.org/10.1201/9781351046510-19.
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Sastry, K. Subramanya, Bikash Mandal, John Hammond, S. W. Scott, and R. W. Briddon. "Sesbania grandiflora (Vegetable hummingbird)." In Encyclopedia of Plant Viruses and Viroids, 2207–8. New Delhi: Springer India, 2019. http://dx.doi.org/10.1007/978-81-322-3912-3_838.
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Thakkur, Manisha, Hagera Dilnashin, and Priyanka Kumari Keshri. "Natural Herbs Polishing Memory: Neuroprotection against Alzheimer's Disease." In Traditional Medicine for Neuronal Health, 265–83. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815040197123010017.
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Alzheimer's Disease (AD) is an irreversible and progressive neurodegenerative disorder that directly deteriorates the memory and cognitive function of the human brain in such a way that a person finds difficulties in dealing with daily life tasks. It is characterized by irregular neurofibrillary tangles (NFTs), intraneuronal accumulation, and the development of senile plaque (SP) consisting of abnormal polypeptide accumulation called βA4 amyloid. The pathophysiology can be collectively explained by five major hypotheses that are amyloid β (A β) hypothesis, the hyperphosporelated tau hypothesis, chronic inflammation, the cholinergic hypothesis, and the metal ion hypothesis. WHO estimated that a total of 40 million people worldwide are tested for the ill effects of dementia, and this is predicted to be twice as high as 114 million by around 2050. Currently, FDA-approved treatments for Alzheimer’s involve Donepezil, Rivastigmine, Galantamine, and Memantine that do not act specifically against Alzheimer's pathology and are also associated with loss of appetite, increased frequency of bowel movements, mental confusion, and dizziness as their side effects promote the approach to disease-modifying drugs. Nowadays, treatment with herbal medicines is a powerful alternative worldwide due to their high safety of margin against the side effects of allopathic drugs. Herbs are not restricted to a specific activity; they are generally enclosed with lignans, flavonoids, tannins, triterpenes, sterols, and alkaloids with wide pharmacological activities, such as anti-inflammatory, anti-amyloidogenic, anti-cholinesterase, and anti-oxidant effects. Many herbal plants of India, such as Glycyrrhiza glabra, Acorus calamus, Convolvulus pluricaulis, Centella asiatica, Sesbania grandiflora, etc., have already proved their efficacies in treating dementia in various scientific studies.