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1

Edberg, Christopher, and Oliver Kjellander. "Calendar Anomalies in the Nordic Stock Markets : A quantitative study of the Sell in May effect, January effect & Monthly Anomalies." Thesis, Linnéuniversitetet, Institutionen för ekonomistyrning och logistik (ELO), 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-105272.

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This study has applied a geographical perspective with the ambition of evaluating the presence of the Sell in May effect, January effect and monthly anomalies in the Nordic stock markets. In extension the study examines the relationship between corporate size and the returns of calendar anomalies. The study has conducted statistical tests based on Newey-West regressions as well as a Generalized Auto-Regressive Conditional Heteroscedasticity model. The findings suggest that the Sell in May and January are present in the Nordic region and partially abide by theory and results of previous research. The findings suggest that the Sell in May and January effect are independent, however, tendencies when the January effect has a considerable influence on the Sell in May effect are also evident. Additionally, the “April Effect” is an unexpected outlier with positive excess returns that was identified through this study.
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2

Schumann, Fernando. "O mercado acionário brasileiro é eficiente?" Universidade do Vale do Rio dos Sinos, 2013. http://www.repositorio.jesuita.org.br/handle/UNISINOS/4232.

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A eficiência ou não dos mercados é um assunto que permanece polemizado por diversos acadêmicos e profissionais do mercado, na medida em que alguns sugerem sua eficiência, e outros se mostram contrários a essa ideia. Nesse contexto, o objetivo deste trabalho é o de verificar se os mercados acionários brasileiros podem ser considerados eficientes, na forma fraca, bem como investigar a possiblidade de existência de anomalias de mercado conhecidas como "efeito segunda-feira" e "efeito sell in may and go away". Com a finalidade de verificar a eficiência de mercado, utilizamos os testes de raiz unitária Dickey-Fuller Aumentado (ADF) e Phillips-Perron (PP). Para a constatação de presença do efeito segunda-feira, empregamos dois procedimentos, quais sejam: estimação dos coeficientes de regressão com o uso de variáveis dummies e teste de Wald, para averiguar uma possível igualdade estatística dos coeficientes; e teste F da Anova e teste de Kruskal-Wallis, para verificação de igualdade de médias e medianas, respectivamente. No que concerne à apuração do efeito sell in may and go away, foram utilizados apenas os testes F da Anova e teste de Kruskal-Wallis. Os resultados apresentados sugerem a eficiência do mercado na forma fraca, bem como a não identificação do efeito segunda-feira. No entanto, foi constatada a presença do efeito sell in may and go away para os ativos CSNA3 e USIM5, de acordo com a metodologia proposta, ou seja, uma sazonalidade favorável nos meses de novembro a abril para os respectivos ativos, o que, em suma, contraria a Hipótese de Mercados Eficientes (HME).
The efficiency of the markets or not is a matter that remains polemic by several academics and market professionals, in the sense that some studies suggest its effectiveness, and others show themselves against this idea. In this context, the aim of this work is to verify whether the Brazilian stock markets may be considered efficient in the weak form, as well as investigate the possibility of existence of market anomalies known as “Monday Effect” and “Sell in may and go away Effect”. In order to verify the market efficiency, we used Augmented Dickey-Fuller (ADF) and Phillips-Perron (PP) unit root tests. For the observation of Monday effect presence, we employed two procedures, namely: estimation of the regression coefficients using dummy variables and Wald test to investigate a possible statistical equality of the coefficients; and Anova F test and Kruskal-Wallis test to check for equality of means and medians, respectively. Regarding the calculation of Sell in may and go away effect, it was used only Anova F and Kruskal-Wallis tests. The results suggest the market efficiency in the weak form, as well as the no identification of Monday effect. However, it was found the presence of Sell in may and go away effect for the assets CSNA3 and USIM5, according to the methodology proposed, that is, a favorable seasonality in the months from November to April for the respective assets which, in short, contradicts the Efficient Market Hypothesis (EMH).
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3

Ahlström, Andreas, and Johan Löfgren. "Sell in may and go away : Effektens existens och utveckling på Stockholmsbörsen." Thesis, Uppsala universitet, Företagsekonomiska institutionen, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-346249.

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Studien undersöker om den svenska aktiemarknaden i regel presterar sämre mellan månaderna maj och september enligt den så kallade “ sell-in-may-and-go-away- effekten”. Vi använder den logaritmerade avkastningen för det svenska indexet OMXS30 som delas upp i olika perioder; maj till september, samt oktober till april. Avkastningen för dessa perioder jämförs genom att använda en regressionsmodell. Resultatet från undersökningen visar att effekten är positiv, samt signifikant på en-procentsnivå mellan 1986 till 2017 för OMXS30 iSverige. Studien tittar även på sell-in-may-and-go-away- effektens utveckling, och finner indikationer för att effekten avtar efter publiceringen av Bouman & Jacobsens undersökningav effekten år 2002. Indikationen på att effekten avtar kan betyda en högre grad av rationalitet hos investerare samt en mer effektiv marknad allt eftersom sell-in-may-and-go-away- effekten blir mer allmänt känd. Resultatet för att effekten skulle vara avtagande är dock inte statistisk signifikant och därmed inte heller statistiskt säkerställd.
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4

Lanson, Logan J. "Sell, Sell, Sell, An Exploratory Analysis of Criminal Justice Education and the Shift to Consumerism." Bowling Green State University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1585826005246563.

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5

Idowu, Olusola Ige. "Effect of improper curing on concrete properties that may affect concrete durability." Thesis, University of Leeds, 2017. http://etheses.whiterose.ac.uk/19158/.

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The use of concrete increasing annually due its favourable properties and readily availability. Demand for concrete will continue to increase and it will remain the world’s most important construction materials for many years to come. However, the use of Portland cement concrete has an environmental burned, and so in a drive to reduce the carbon footprint of construction, there is widespread attention directed towards the utilisation of wastes and industrial by-products to minimise Portland cement (PC) consumption. The cement industry increasingly uses additions, such as fly ash. The literature has established the use of fly ash as partial replacement of Portland cement to increase strength at later age and exhibit considerable enhancement in durability. However, such binders hydrate more slowly, so proper curing conditions become more important. Ideally, the durability of concrete should not be a concern. Some degree of weathering should be expected, but improper concreting procedures can cause the deterioration to be earlier than expected. Furthermore, since durability issues cannot be seen immediately, some assessment of the impact of improper concrete curing is needed. The study has involved casting of concretes prepared with either CEM I or a CEM I blend with 30% replacement with fly ash to investigate the impact of improper curing. Performance was evaluated in terms of compressive strength, drying shrinkage, transport properties and resistance to carbonation. Paste samples were characterised by TGA, XRD and SEM to follow hydration and microstructural development. Also since the degree of saturation is known to affect the compressive strength of concrete, and curing under ambient conditions will lead to changes in the degree of concrete saturation, the work checked the impact of the degree of saturation on compressive strength; to enable an accurate understanding of the impact of improper curing. Improper curing leads to reduced compressive strength development and increased drying shrinkage. Sorptivity and permeability values were increased. This is due to reduced levels of cement hydration, as water evaporates from the concrete surface. The effect of improper curing on resistance to carbonation revealed that samples improperly cured carbonated more than those ideally cured. This study has shown that the impact on sorptivity and permeability is far greater than the impact on compressive strength, with implications for the long-term durability of concrete. Composite cements, containing 30% fly ash, showed comparable strengths to CEM I concretes and improved transport properties when ideally cured. Additions of fly ash reduced the drying shrinkage. Improper curing however led to reduced performance. Strength was compromised by improper curing to a greater degree than for equivalent CEM I mixes. However, it was sorptivity and permeability which were most severely affected. This was due to the reduced degree of cement hydration leading preventing the pozzolanic reaction between the fly ash and portlandite. Also, higher carbonation depth was seen on fly ash samples that were not cured. Low strength concrete, which already has an inherently higher porosity, is more greatly affected by improper curing than high strength concrete. This is presumed to be due to the ease with which water can evaporate from the surface of the more porous matrix. Also, concrete workability has been found to be a factor which can help to reduce the embodied carbon of concrete, with stiffer mixes having lower carbon footprints. However, this study has shown that stiff concrete mixes may be less durable and more susceptible to improper curing. This may be explained by the lower overall water contents within the stiff mixes, and therefore the greater impact of surface water evaporation. The effect of changes in the degree of saturation showed the deleterious effects of improper curing, with the saturated, ambient cured samples all exhibiting lower strengths than the equivalent ideally cured samples. The large capillary pores developed due to improper curing was seen with lower calcium hydroxide contents. The reduced hydration products obtained support the result that lower degree of hydration was produced due to improper curing since the hydration of cement cannot continues in the dry environment. This study confirms the need for good site practice, and shows that embodied carbon should not be the only factor when considering the environmental performance of concrete. Rather, durability and whole life performance should also be considered.
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6

Nyman, Madeleine. "Biomarkers for exposure and for the effects of contamination with polyhalogenated aromatic hydrocarbons in Baltic ringed and grey seals." Helsinki : University of Helsinki, 2000. http://ethesis.helsinki.fi/julkaisut/mat/ekolo/vk/nyman/.

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7

Benazzouk, Louiza. "Approche du comportement dynamique d'un oxyde liquide dans un matériau composite autocicatrisant " MAC "." Phd thesis, Université Sciences et Technologies - Bordeaux I, 2013. http://tel.archives-ouvertes.fr/tel-00984446.

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Les matériaux composites à matrice céramique CMC, sont généralement formés d'au moins deux matériaux ayant une forte capacité d'adhésion. Ces matériaux sont principalement composés de renforts fibreux assurant la tenue mécanique de la structure et d'une matrice qui permet sa cohésion. Utilisées principalement dans le domaine de l'aéronautique, elles sont reconnues pour leur bonne tenue mécanique, leur réfractarité élevée tout en conservant une densité faible. Par contre, l'inconvénient majeur associé à ces matériaux est l'apparition de fissures qui sont dues soit au procédé de fabrication soit aux sollicitations mécaniques externes.Dans ce travail, une attention toute particulière est consacrée aux composites à matrice auto-cicatrisante dont la principale propriété est l'aptitude à "réparer" les effets de la fissure par formation d'un verre visqueux.Ces verres visqueux se forment au sein de la fissure grâce à l'oxydation des éléments qui constituent la matrice. Selon la température, différents verres peuvent être formés.Leur fonction est de reboucher les fissures de taille micrométrique de façon à ralentir la diffusion de l'oxygène en direction des fibres et éviter leur rupture par oxydation.Cependant, pour des systèmes en rotation rapide tels que les turbines basse pression des moteurs d'avion (pièce étudiée actuellement), on peut s'interroger quant à la mobilisation du verre visqueux cicatrisant dans un système complexe géométriquement et inhomogène du point de vue de la nature des surfaces. Pour approcher le comportement du verre cicatrisant dans un système modèle mais néanmoins réaliste, une approche de modélisation numérique a été entreprise. L'outil numérique utilisé pour cette étude est le code de calcul Thétis développé à l'I2M. Celui-ci est adapté à ce type de simulation puisqu'il permet la modélisation d'écoulements diphasiques incluant des phénomènes physiques complexes tels que le mouillage. Ainsi, l'objectif de ce travail est-il de déterminer les limites d'utilisation de ce type de matériau en fonction des conditions auxquels il est soumis en évaluant la mobilité du verre cicatrisant dans la fissure.
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8

May, Sarah [Verfasser]. "The effect of different engineered nanomaterials (ENMs) on DNA damage and repair pathways / Sarah May." Konstanz : KOPS Universität Konstanz, 2018. http://d-nb.info/1204005001/34.

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9

Calabrese, Monica K. "Effects of relationship type patterns on satisfaction and self-esteem in heterosexual relationships." Instructions for remote access. Click here to access this electronic resource. Access available to Kutztown University faculty, staff, and students only, 1999. http://www.kutztown.edu/library/services/remote_access.asp.

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Thesis (M.A.)--Kutztown University of Pennsylvania, 1999.
Source: Masters Abstracts International, Volume: 45-06, page: 2775. Typescript. Abstract precedes thesis as preliminary leaf vi. Includes bibliographical references (leaves 27-29).
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10

Douglas, Emily A. "The effects of verbally aggressive messages on women's self-concepts within romantic relationships." Virtual Press, 2007. http://liblink.bsu.edu/uhtbin/catkey/1365177.

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The purpose of this study was to examine the effects of verbally aggressive messages on women's self-concepts within romantic relationships. Through a qualitative methodological approach, this study examined the effects of such messages in the role of control negotiation, effects on women's self-concepts, and effects on future communication patterns. Through one-on-one interviews, women who have previously been in verbally abusive relationships were given the opportunity to share their individual stories through a narrative analysis. In addition, the theories of Communication Theory of Identity and Relationship Scripts were applied to understand the relationship between the effects of the messages on attitudes, behaviors, sense of identity, and communication patterns of the participants.The results indicated negative effects on victims who have experienced verbally abusive relationships. The need for control exemplified by the male aggressors resulted in compliance by the participants. The participants also experienced lower self-esteem and change or loss of personal identity, which affected communication in subsequent romantic relationships.
Department of Speech Communication
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11

Nguyen, Thao T. "Self-constructions as mediating and additive effects on perceptions of conflict resolution strategies and relationship satisfaction interdependent and independent self-construals /." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/MQ56194.pdf.

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12

Grant, C. C. (Catharina Cornelia). "The effect of intensive physical training on cardiac autonomic variability - factors that may influence the results." Thesis, University of Pretoria, 2011. http://hdl.handle.net/2263/24161.

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The study dealt with the influence of exercise on the autonomic nervous system (ANS) and with factors that may influence the results. ANS function was measured in 183 young, healthy participants, before and after a twelve week standardised, medium-to-high volume physical training programme, in a controlled environment. The effects of the training programme were assessed on resting ANS functioning, during standing and on the response to an orthostatic challenge. ANS function was assessed by means of heart rate variability (HRV) determination. HRV was quantified by three different analytical techniques, i.e., time domain analysis (RR, STDRR, RMSSD and pNN50), frequency domain analysis (LF,LFnu, HF, HFnu and LF/HF) and Poincaré plot analysis (SD1 and SD2). The influence of technical variations, such as variations in tachogram length and period of recording, as well as the influence of pre-intervention values of physiological variables, such as blood pressure, BMI, VO2 max and ANS functioning, on the response to the exercise intervention, were assessed. Results on the exercise intervention showed:
  • Increased supine, as well as standing, parasympathetic cardiac control as indicated by time domain, frequency domain and Poincaré analyses.
  • Decreased sympathetic control in the supine position and increased sympathetic control during rising and standing.
  • Increased vagal withdrawal, as well as increased sympathetic control during the first phase of the orthostatic response to rising from the supine position.
  • Only an exercise-induced increase in sympathetic control when the orthostatic response was measured as the difference between standing and supine.
Results on exercise-induced changes in sympathetic and parasympathetic ANS control differ, depending on posture. It is suggested that the effects of an exercise intervention on sympathetic and parasympathetic ANS control of the heart should be assessed from measurements in the supine, in the standing, and in response to an orthostatic stressor. It is further suggested that information obtained during rising will give additional information on the response of the ANS. This study showed that technical as well as physiological variations may lead to differences in the outcome of HRV studies. Results from the technique evaluation showed that the length and period of tachogram recordings should be standardised, especially during an orthostatic challenge. Starting the recording too late will miss out on the initial response to a change in body position. Longer recording times will represent the mean of HRV values obtained during the orthostatic response and that obtained after stabilisation in the standing position. Investigations into the influence of pre-intervention physiological status on exercise-induced changes showed:
  • Baseline ANS functioning is a significant contributor to variations in the ANS response to an exercise intervention.
  • Pre-intervention values for physiological variables, such as blood pressure, BMI and VO2 max do not have a significant influence on the HRV response to exercise in young, healthy individuals of average fitness
  • Regression analyses confirm the correlation results, i.e. that baseline ANS function is a significant predictor of the ANS response to exercise.
  • However, regression results indicated that the combination of pre-intervention values for LFms2, HFms2, BMI, VO2 max, gender and blood pressure, contributes only between 12.83% and 29.82%, depending on the HRV variable, to the exercise induced changes in the autonomic nervous system.

Thesis (PhD)--University of Pretoria, 2011.
Physiology
unrestricted
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13

Dal, Savio Claudio. "Spectroscopy of size dependent many-particle effects in single self-assembled semiconductor quantum dots." [S.l.] : [s.n.], 2006. http://deposit.ddb.de/cgi-bin/dokserv?idn=979606683.

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14

Rethwisch, Michael D., Krystyl Bolin, Jessica L. Grudovich, Jessica Wellman, Dyke Charles Van, Juan Vingochea, Marlo Barron, and Mark Reay. "Effect of two-spotted spider mites and miticides on alfalfa hay produced for a late May cutting." College of Agriculture, University of Arizona (Tucson, AZ), 2004. http://hdl.handle.net/10150/203870.

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Three miticide treatments (milbemectin, clarified neem oil, and chlorpyrifos plus dimethoate) were compared with an untreated check to obtain information on the effects of twospotted spider mite (Tetranychus urticae) feeding on alfalfa yields, quality and economics, as well as crop responses to miticides. Mite infested alfalfa was treated just prior to first irrigation after cutting in spring 2003, and numbers of spider mites and western flower thrips (Frankliniella occidentalis) were obtained at weekly intervals thereafter for the next seven weeks. Data for plant parameters (stem widths, numbers of leaves, internode lengths) were obtained at harvest, as were hay yields and quality. The milbemectin treatment resulted in quickest reduction of spider mites (88.5% at 5 days after application) and also resulted in significantly higher yields than the untreated check (0.18 tons of hay/acre), attributed to the longer internodes and resultant tallest plants and significantly thicker stems than the untreated check. Clarified neem oil and chlorpyrifos plus dimethoate treatments did not control spider mites as quickly as milbemectin and yields were increased by only 0.04-0.05 tons hay per acre in this experiment compared with the untreated check. These two treatments also differed in their effects on stem widths and internode lengths, indicating that some results noted were a result of interactions of miticides with alfalfa as well as spider mite control.
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15

Pitthan, Francisco do Nascimento. "How the disposition effect may explain momentum: the relationship between investment behavior biases and brazilian market movements." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/12/12138/tde-13112018-130943/.

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Momentum is one of the most robust anomalies in financial markets, there are two main recent explanations for this phenomenon, a behavioral-based explanation through disposition-effect (i.e., the willingness to sell \"winners\" too quickly and to hold \"losers\" for a long time) and a fund-flow based explanation. The disposition-effect explanation is centered in the convergence of the spread between the fundamental value and the observed market price (disposition-effect causes an underreaction to news that generates this spread), and the fund flows-based explanation is due to the persistence of the performance of mutual-funds (which usually keep buying winning positions and selling the losses). This master thesis compares those theories using Brazilian data (which is suitable for the strong presence of momentum). Our empirical analysis was done using Fama-MacBeth regressions with results pointing the disposition-effect explanation as the most significant, with our robustness analysis contributing positively to the main findings.
Uma das anomalias mais robustas presente nos mercados financeiros é a existência de momentum nos preços de ações, existem duas principais explicações recentes para este fenômeno: explicação comportamental através do efeito-disposição (i.e. disposição de vender ativos \"vencedores\" rapidamente e de segurar ativos \"perdedores\" por muito tempo) e explicações de fluxos de fundos de investimento. A explicação através do efeito-disposição é centrada na convergência do spread entre o valor fundamental de um ativo e o preço de mercado observado (o efeito-disposição causa uma reação branda a notícias que gera esse spread), e a explicação baseada em fluxos de fundos que se deve pela persistência da performance de fundos (que usualmente continuam comprando posições vencedoras e vendendo as perdedoras). O objetivo desta dissertação é comparar essas teorias utilizando dados brasileiros (que é adequado pela forte presença de momentum). Nossa análise empírica foi feita através de regressões de Fama-MacBeth com resultados apontando a explicação centrada no efeito-disposição como a mais significativa, com nossa análise de robustez contribuindo positivamente para nossos resultados principais.
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16

Grasty, Monica R. "Let the Seeds Fall Where They May: Investigating the Effect of Landscape Features on Fine-Scale Seed Dispersal." PDXScholar, 2017. https://pdxscholar.library.pdx.edu/open_access_etds/4001.

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Seed dispersal is a crucial ecological and evolutionary process that allows plants to colonize sites and expand their ranges, while also reducing inbreeding depression and facilitating the spread of adaptive genetic variation. However, our fundamental understanding of seed dispersal is limited due to the difficulty of directly observing dispersal events. In recent years, genetic marker methods have furthered our understanding of colonization and range expansion due to seed dispersal. Most investigations focus on regional scales of dispersal, due to low levels of variation in the chloroplast genome (cpDNA), which can serve as an indirect measure of seed dispersal. Here, I employ a whole-genome assay of cpDNA variation in Plagiobothrys nothofulvus to resolve variation due to patterns of seed dispersal within a 400x400 meter section of the Whetstone Savanna Preserve in Central Point, OR, USA. Whetstone is characterized by a mosaic of habitat types, including vernal pools, hummocks of dry prairie, and large Ceanothus cuneatus bushes, as well as a network of vole runways. Plagiobothrys nothofulvus grows in dense patches on hummocks within this prairie. I found evidence of limited seed dispersal in P. nothofulvus, indicated by strong genetic structure over distances of less than 100 meters. There was little evidence that geographic distance predicts genetic distance; environmental features have a stronger influence on dispersal. Habitat preference was the strongest predictor of genetic variation in P. nothofulvus, indicating that it may be a habitat specialist in this prairie. Flower density also accounted for a significant portion of dispersal, which may be a consequence of the annual life history of P. nothofulvus resulting in seasonal turnover and lack of competition with adult plants. Least-cost-path analysis indicated that seeds are secondarily dispersed by small mammals along vole runways. Overall, I found significant evidence that landscape features influence dispersal, even at a very fine spatial scale.
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FERREIRA, VINICIUS FADINI B. DE M. "THE SIZE EFFECT ON FIRMS RETURNS IN THE BRAZILIAN MARKET AND HOW THE CONTROL FOR OTHER FACTORS MAY INFLUENCE RESULTS." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2017. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=33190@1.

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Esta dissertação busca replicar, para o mercado brasileiro, a abordagem e as metodologias utilizadas por Asness, Frazzini e Perdersen (2015) na tentativa de verificar a existência de prêmio positivo entre os retornos de firmas pequenas e firmas grandes no mercado norte-americano. Adicionalmente, procura mensurar como o fator Qualidade entre outros, poderiam influenciar no resultado desse prêmio, otimizando-o ou não de acordo com o controle para tais variáveis. O trabalho se pauta no modelo clássico de precificação de Fama e French, tanto para definir o fator que representará o prêmio por tamanho como para a criação de diversos portfólios que resultam nos outros fatores a serem considerados nas regressões de cada estudo.
This paper seeks to replicate, for the Brazilian market, the approach and methodologies used by Asness, Frazzini and Perdersen (2015) in an attempt to verify the existence of a positive premium among the returns of small firms and large firms in the North American market. In addition, it seeks to measure how the Quality factor, among others, could influence the results of this premium, optimizing it or not according to the control for such variables. The paper is based on the classic Fama and French pricing model, both to define the factor that will represent the size premium and creation of several portfolios that result in the other factors to be considered in the regressions of each study.
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Poyntz, Hazel Claire. "Evaluation of the immunological mechanisms induced by mycobacteria and the potential effect this may have on immunity induced by tuberculosis vaccines." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:e7f1890e-577e-4346-b7fa-7ae810aa1be4.

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The efficacy of Bacille-Calmette Guerin (BCG) vaccination in protection against pulmonary tuberculosis (TB) is highly variable between populations. One possible explanation is increased exposure of certain populations to non-tuberculous mycobacteria (NTM). Given the variable efficacy of BCG an improved vaccine against TB is required. The novel TB vaccine MVA85A has shown promising results, however, the immunogenicity of the vaccine is reduced when it is administered in the Expanded Programme on Immunisation (EPI) schedule. This thesis aims to explore: (A) the effect of exposure to NTM on the level of protection afforded by BCG vaccination against Mycobacterium tuberculosis (M. tb) and (B) the immunological mechanisms behind EPI interference with MVA85A. The effect of M. avium (MA) exposure via systemic and oral routes on the efficacy of BCG was tested using M. tb aerosol infection in a mouse model. The adaptive immune response was profiled in BCG vaccinated mice with and without exposure to MA pre- and post- M. tb infection. The results showed BCG efficacy could be enhanced by exposure to dead MA by a systemic route; T helper 1 and T helper 17 responses were associated with increased protection. In contrast, BCG efficacy may have been reduced by exposure to live MA by the oral route; T helper 2 and regulatory T cells were associated with reduced protection. To answer the second aim MVA85A was co-administered to mice with aluminium adjuvants or aluminium-containing vaccines to replicate the effect of co-administration in the EPI schedule; the adaptive immune response was profiled. T helper 2 and regulatory T cell responses induced by aluminium-containing vaccines were associated with a reduction in the immunogenicity of MVA85A.
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19

Anderzon, Samuel, and Filip Davidsson. "Agile Practices in Production Development : Investigation of how agile practices may be applied in a production development context and what the expected effects are." Thesis, Jönköping University, JTH, Produktionsutveckling, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-53736.

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Globalization has continuously brought an increased competition among companies, which entails a need for faster and more frequent deliveries of new products. Traditional project management methods, such as stage-gate and waterfall, are commonly used in production development projects and builds on a sequential approach. These methods have proven to have some disadvantages in flexibility, long lead times and it often creates communication barriers between the actors at each stage. The software industry has already encountered these obstacles and responded by introducing agile project management. Which improves the adaptability and allow changes to be made, due to new requirements from stakeholders or customers, throughout the entire development process. However, it remains unknown how agile models can improve production development. The purpose of this study was therefore to investigate how agile models can be applied to production development and what the effects are.  The authors have performed a case study at eight different companies within the automotive industry. The purpose of it has been to gain a deeper understanding about the case companies current production development processes and review how familiar the organizations are with the concept of agile project management. The extraction of the empirical data was conducted by questionnaires, interviews, and document reviews. An analyzation was done by comparing the empirical findings with the theoretical background out of eleven different categories that relates to project management (e.g., project goals, process, customer integration etc.). The analyzation concluded that the case company exclusively conducts their production development project by using a sequential approach.  The analyzation and the eleven categories where, together with the theoretical background about agile project management, later used to create the result by brainstorming different practices to become more agile. The results are presented out of three different scenarios, depending how agile the companies would like to be. For instance, are two process models suggested, one that is completely agile and one that is a hybrid of an agile and a stage-gate. Furthermore, are the implementation of self-organized teams, holistic approach towards internal and external partners, and reduced demand for documentation some of the practices that are suggested. Additionally, are three considerable aspects for the implementation presented.  The expected outcome and effects of applying these practices are discussed in the final chapter. Some of these outcomes are a company culture that will attract and retain talented personnel, where shared responsibilities and authorities triggers the employees to an increased commitment and sense of ownership towards their projects. Furthermore, are the companies expected to experience a more flexible and responsive approach towards conducting production development projects with a high focus on customer requirements and creating customer value.
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Bruns, Anne Mareike [Verfasser], Angelika [Akademischer Betreuer] May, and Jörg [Akademischer Betreuer] Prokop. "Alternative investments: an empirical study of their risk-minimizing effect on European banks' portfolios with equities and bonds / Anne Mareike Bruns ; Angelika May, Jörg Prokop." Oldenburg : BIS der Universität Oldenburg, 2021. http://d-nb.info/123822539X/34.

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Reed, Sara. "The Effect of the Introduction of a Clearinghouse on Trading Costs: The New York Stock Exchange in the 1890s." Scholarship @ Claremont, 2011. http://scholarship.claremont.edu/cmc_theses/290.

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As one of the oldest and most innovative financial institutions, a clearinghouse efficiently clears and settles payments for equity transactions as well as other securities. However, this paper will only be concerned with common and preferred equity securities. The purpose of a clearinghouse is to reduce counterparty risk. It acts as an intermediary between two parties, so that the risk of one party failing to honor its contractual obligation is diminished. It reduces settlement risk through netting, the process of eliminating offsetting transactions, thus decreasing the amount of cash flow. I examine the impact of the New York Stock Exchange Clearinghouse upon its establishment in May 1892. Specifically, I analyze the clearinghouse’s effect on trading costs for different equity securities, scrutinizing the effects on bid-ask spreads. I find that once a firm joined the NYSE clearinghouse, both its relative and absolute bid-ask spreads are narrowed, representing an overall reduction in spreads of 5.28 percent.
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Doak, Kate Louise. "Alterations in the glycosylation pattern of alpha-1-glucoprotein may be diagnostic for the detection of breast cancer and/or reducing the effect of chemotherapy in vivo." Thesis, University of Strathclyde, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501891.

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23

Kuusisto, S. (Sanna). "Effects of heavy alcohol intake on lipoproteins, adiponectin and cardiovascular risk." Doctoral thesis, Oulun yliopisto, 2014. http://urn.fi/urn:isbn:9789526206264.

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Abstract The effect of alcohol intake on the pathophysiology of atherosclerotic cardiovascular disease is controversial, especially with respect to heavy alcohol intake. The pathobiology behind atherosclerosis is a complex and multiparametric phenomenon, therefore a self-organizing map (SOM), an unsupervised learning based artificial neural network technique, was applied in the present work. This study was carried out to investigate the effect of heavy alcohol intake on the pathophysiology of atherosclerosis, including several lipoproteins and adiponectin, an adipocyte-derived cytokine that may ameliorate atherosclerosis. Firstly, the effect of heavy alcohol intake on the capacity of HDL and its subclasses (HDL2 and HDL3) to mediate cholesterol efflux from macrophages was studied. Secondly, data of ultracentrifugally isolated lipoproteins were fed into SOM analysis to investigate whether this method can find diverse lipoprotein phenotypes from the heterogeneous lipoprotein data. Thirdly, the aforementioned method was applied to multivariate data of alcohol drinkers to study whether distinct metabolic profiles are associated to heavy alcohol consumption. The results revealed that HDL2, not HDL3, of heavy alcohol drinkers had an enhanced capacity to remove cholesterol from macrophages when compared with control persons. SOM analysis enhanced the ultracentrifugally based lipoprotein data and depicted several novel lipoprotein phenotypes. In addition, lipoprotein-based SOM analysis found two distinct metabolic profiles in heavy alcohol drinkers: an anti-atherogenic and a metabolic syndrome-like profile with opposite metabolic features, such as characteristics of lipoproteins, plasma concentration of adiponectin and prevalence of metabolic syndrome. These profiles also tended to differ in their CV risk. In conclusion, the enhanced cholesterol efflux capacity of HDL2 in heavy drinkers is an anti-atherogenic change linked to alcohol drinking. However, clinically it may be important to be aware that although heavy alcohol drinkers have a low LDL-C level, they differ in their other lipoprotein measures, forming distinct phenotypes with potentially different CV risks. Finally, SOM analysis of ultracentrifugally based lipoprotein data generates in silico classification of lipoprotein particles and thereby offers a new tool for lipoprotein research
Tiivistelmä Alkoholinkäytön vaikutus ateroskleroottisen sydän- ja verisuonitaudin patofysiologiaan on kiistanalainen, etenkin runsaan alkoholinkäytön kohdalla. Koska patobiologia ateroskleroosin taustalla on monimutkainen ilmiö, tässä työssä sovellettiin menetelmänä itseorganisoituvaa karttaa, joka on ohjaamattomaan oppimiseen perustuva neuroverkkomalli. Tutkimuksen tavoitteena oli selvittää runsaan alkoholinkäytön vaikutusta ateroskleroosin patofysiologisiin merkkiaineisiin, mukaan lukien useita lipoproteiineja sekä adiponektiini, rasvasoluperäinen sytokiini, joka voi lievittää ateroskleroosia. Ensimmäisessä osatyössä tutkittiin runsaan alkoholinkäytön vaikutusta HDL:n ja sen alafraktioiden (HDL2 ja HDL3) kykyyn poistaa kolesterolia makrofageista. Toisessa osatyössä ultrasentrifuugaukseen perustuva lipoproteiiniaineisto syötettiin itseorganisoituvaan karttaan. Työssä selvitettiin löytäisikö menetelmä erilaisia lipoproteiinifenotyyppejä heterogeenisestä aineistosta. Kolmannessa osatyössä em. menetelmää sovellettiin monimuuttuja-aineistoon, joka koostui runsaasti alkoholia käyttävistä ja verrokeista. Tutkittiin, liittyykö runsaaseen alkoholinkäyttöön erilaisia metabolisia profiileja. Tulokset osoittivat, että suurkuluttajien HDL2-hiukkasen kolesterolinpoistokyky makrofageista oli suurempi kuin verrokeilla. Itseorganisoituvaan karttaan perustuva lipoproteiinien luokittelumenetelmä löysi useita uusia lipoproteiinifenotyyppejä. Lisäksi, em. menetelmä löysi suurkuluttajilta kaksi erilaista metabolista profiilia: anti-aterogeeninen ja metabolisen syndrooman kaltainen. Näillä oli vastakkaiset metaboliset piirteet, kuten lipoproteiinien ominaisuudet, adiponektiinin pitoisuus plasmassa ja metabolisen syndrooman esiintyvyys. Profiileihin liittyi mahdollisesti myös erilainen sydän- ja verisuonitautiriski. Tutkimus osoittaa, että alkoholin suurkuluttajilla havaittu parempi HDL2:n kyky poistaa kolesterolia soluista on anti-aterogeeninen muutos, joka liittyy alkoholin käyttöön. Kliinisesti voi olla merkittävää, että vaikka alkoholin suurkuluttajilla oli pieni LDL-C pitoisuus, he jakaantuivat muiden lipoproteiiniperäisten muuttujien perusteella kahteen eri fenotyyppiryhmään, joihin liittyi erilainen sydäntautiriski. Lisäksi itseorganisoituva kartta loi ultrasentrifugoinnilla eristetyille lipoproteiineille in silico -luokittelun, joten se tarjoaa uuden työkalun lipoproteiinitutkimukseen
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Kunsch, Graziela Krohling. "Não caber + Início da pesquisa Estou na frente da câmera mas a minha cabeça está atrás dela ou A performance da diretora ou A performance da crítica." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/27/27161/tde-14092016-111556/.

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1) A pesquisa artística não pode se subordinar à obediência acadêmica. 2) A presença de cineastas como personagens de seus próprios filmes, interpretando seus próprios papeis, talvez seja o mais próximo que o cinema chega da performance. Essa presença, de caráter supostamente documental, se dá sempre com a consciência que o realizador/a realizadora tem da câmera, de modo que exerce o duplo papel de atorencenador (como Renato Cohen descreve o performer) ou protagonista-observador de sua própria atuação (Jorge Glusberg). A frase que dá título à esta parte da pesquisa - \"Estou na frente da câmera mas a minha cabeça está atrás dela\" - foi dita por Jean-Luc Godard durante a sua participação no filme Quarto 666, de Wim Wenders. 3) A crítica do artista tende a ser sempre individual; a verdadeira crítica só pode ser coletiva.
1) Artistic research cannot be subordinated to academic obedience. 2) The presence of filmmakers as characters in their own movies, playing their own roles, is perhaps the closest cinema gets to performance. This presence, supposedly documentary-oriented, always occurs with the awareness that the director has of the camera, so that he/she performs the dual role of actor-director (as Renato Cohen describes the performer) or actor-observer of his own performance (Jorge Glusberg). The sentence used as title of this part - \"I\'m in front of the camera but my head is behind it\" - was said by Jean-Luc Godard while participating in the film Room 666, by Wim Wenders. 3) Artist\'s criticism tends to be always individual; the real criticism has to be collective.
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Celik, Sule. "The Effects Of An Attachment-oriented- Psychoeducational-group-training On Improving The Preoccupied Attachment Styles Of University Students." Phd thesis, METU, 2004. http://etd.lib.metu.edu.tr/upload/3/12605253/index.pdf.

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The purpose of this study is to examine the effect of an Attachment-Oriented-Psychoeducational-Group-Training on the preoccupied/insecure attachment style of university students. This study consists of two phases. In the first phase of the study, Relationship Scales Questionnaire (RSQ), Relationship Questionnaire (RQ), Rosenberg Self-Esteem Scale (RSS), and an Information Form were given to the 755 third year METU students. The differences among the attachment styles (RSQ and RQ) of the participants by gender and self-esteem levels (RSS) were explored by using a 2 (gender) x 2 (high-low self-esteem) factorial MANOVA. Results showed significant self-esteem differences in fearful, preoccupied and secure subscale scores in RQ and RSQ and gender differences in fearful, preoccupied and secure subscale scores of RSQ and RQ. These results indicated that students who had lower self-esteem scored significantly higher in fearful and preoccupied subscales of RSQ while students who had higher self-esteem had statistically significant higher mean scores in secure attachment subscales. No significant differences were found between the insecure/avoidant subscale scores of the high and low self-esteem group students. Results showed that females scored significiantly higher in fearful attachment style of RQ and RSQ. Male students scored significiantly higher in both preoccupied subscales of RQ and RSQ and in secure attachment subscale of RSQ. In the second phase, the Attachment-Oriented-Psychoeducational-Group-Training was implemented to the experimental group of 11 volunteered preoccupied subjects. The control group consisted of 8 preoccupied students. The control group subjects did not receive any training. Both experimental and control groups were given Relationship Scales Questionnaire and Rosenberg Self-esteem Scale at pre-test, post-test and follow up. Non-parametric statistical analyses of Wilcoxon test and Mann-Whitney U test were employed to the RSQ and RSS scores of the subjects to assess the effect of the Attachment-Oriented-Psychoeducational-Group-Training. The results showed that experimental group subjects&
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secure attachment subscale scores have increased from pre-test to posttest but not pre-test to follow up or posttest to follow up tests of both RSQ and RSS. A significant difference was found between pre and follow up tests scores of RSS for control group.
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Nyblom, Jakob. "What is the price of quality? : Investigating the effect of increased wine quality on the price of a wine and how it may differ between a monopolised and a non-monopolised alcohol market." Thesis, Uppsala universitet, Nationalekonomiska institutionen, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-343312.

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The purpose of this paper is to investigate the effect of an increased wine quality on the price of a wine and how this may differ between a country with a monopolized alcohol market and one that has not. The main reason for this comparison is to analyse whether the politics of the Swedish alcohol monopoly have succeeded in premiering quality over quantity drinking and if that has created possibilities for arbitrage trading of wine. Data regarding the price of wines was gathered from the Swedish alcohol monopoly’s website and VildMedVin, the largest e-commerce for wine in Denmark. One of the largest wine reviewers in the world, Wine Spectator, utilises a 1-100 scale when rating wines; this is used as a proxy for quality. By creating four different regression models it was found  that when it comes to wines that are more expensive than 99 SEK, there is no  statistically significant difference in the effect of quality on the price of a wine between Sweden and Denmark. Indicating that the law of one price might be what denies the possibility of arbitrage between a monopolised and a non-monopolised market is non- existent. There is, however, a general effect in both countries, an increase in quality by 1 unit is associated with an increase in the wine’s price by approximately 8%.
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Beausoleil, Christopher S. "What is the unique and direct effect of an uninvolved father on his son's self-concept as an adult man?, a dialogue between Samuel Osherson's Finding our fathers, social scientists and Christian theology." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape15/PQDD_0013/MQ33799.pdf.

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Aversa, Pierfrancesco. "Primary Defects in Halide Perovskites : Effect on Stability and Performance for Photovoltaic Applications Effect of organic PCBM Electron transport Layers on natural and post-irradiation ageing of optical absorption and emission in methyl ammonium lead triiodide spin –coated on p-i-n Solar Sell Substrates Effect of organic PCBM Electron transport Layers on natural and post-irradiation ageing of optical absorption and emission in triple cation lead mixed halide perovskite spin –coated on p-i-n Solar Sell Substrates Electron Irradiation Induced Ageing Effects on Radiative Recombination Properties of methylammonium lead triiodide layers on p-i-n solar cell substrates Electron Irradiation Induced Ageing Effects on Methylammonium Lead Triiodide Based p-i-n Solar Cells Electron Irradiation Induced Ageing Effects on Radiative Recombination Properties of Quadruple Cation Organic-Inorganic Perovskite Layers." Thesis, Institut polytechnique de Paris, 2020. http://www.theses.fr/2020IPPAX050.

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Ces onze dernières années ont vu apparaitre les pérovskites organiques inorganiques hybrides (HOIPs) comme un passionnant domaine de recherche pour leur application potentielle dans les technologies du photovoltaïque (PV) en raison de leurs exceptionnelles propriétés optoélectroniques et de leur facilité de mise en oeuvre. Cependant, les matériaux HOIPs ont plusieurs inconvénients dont leur manque de stabilité en conditions opérationnelles. Améliorer celle-ci est l'un des plus grands défis à relever avant commercialisation. La formule générale est (A1,A2,A3,A4)Pb(X1,X2)3, où les sites A occupés par une distribution de 1 à 4 cations métalliques/organiques et les sites X par celle d’anions halogénures. Les défauts lacunaires natifs sont considérés comme une cause possible de dégradation des cellules solaires HOIPs. L'objectif de ce travail est de comprendre le rôle des défauts dans la stabilité à long terme des matériaux PV HOIPs. A cette fin, des défauts primaires ont été introduits de manière contrôlée par irradiation avec des électrons de haute énergie (1MeV) dans des lots de couches et cellules solaires (SCs) à base de divers composés HOIPs. Il s'agit notamment du prototype PV HOIPs, MAPbI3 (A1PbX13), et de nouveaux composés mixtes d’halogénures à triple ou quadruple cations, (CsMAFA)Pb(I1-xBrx)3 (A3PbX23) ou (GACsMAFA)Pb(I1-yBry)3 (A4PbX23). Les couches sont fabriquées selon la même procédure que les couches actives SCs et, ensuite, traitées dans des conditions similaires. Pour A1PbX13/A3PbX23, la structure SC est de type p-i-n avec des couches organiques pour le transport des trous et des électrons (HTL/ETL). Les couches sont déposées sur le substrat verre/ITO/HTL (PEDOT:PSS) sans ou avec couche supérieure ETL (PCBM). Pour A4PbX23, la structure SC est de type n-i-p avec des couches ETL inorganiques (TiO2) et HTL organiques (Spiro-OMeTAD). Les couches sont directement déposées sur du verre.La spectroscopie d'annihilation de positons donne une évidence directe de l'existence de défauts lacunaires natifs et induits par irradiation dans chaque composé. Les spectres d’absorbance en fonction de l’énergie montrent que le vieillissement naturel et après irradiation génère différentes populations de défauts dans chaque composé. De plus, celles-ci pour A1PbX13 et A3PbX23 diffèrent selon l'absence ou la présence de la couche supérieure ETL. Les populations de défauts évoluent pendant au moins 3 mois. Le vieillissement modifie (i) la bande interdite, (ii) les queues de bande de conduction/valence et (iii) l'absorption optique via des niveaux électroniques profonds. Les effets d’illumination sous laser varient aussi en fonction du vieillissement. L’asymétrie des pics de photoluminescence (PL) dans chaque composé sous illumination laser continue reflète une superposition de raies d’émission gaussiennes à énergie, FWHM et hauteur évoluant avec le temps d'illumination. Les transitions d'émission impliquent des niveaux électroniques localisés peu profonds dans A3PbX23/A4PbX23 et résonnants dans A1PbX13. De tels effets durent au moins 3 mois dans A4PbX23. Ces niveaux électroniques sont attribués à des populations de défauts spécifiquement induits par illumination. Le vieillissement naturel et après irradiation donne des spectres PL à décroissance temporelle résolue en une ou deux exponentielles. Le nombre et la durée de vie sont fortement influencés par l’irradiation initiale et la composition. Une amélioration frappante du fonctionnement PV pour le type SC p-i-n est induite par le vieillissement dû à l'irradiation. Le rendement quantique externe et les performances PVs ont des valeurs plus élevées pour l’état irradié que de référence durant 6 à 12 mois de vieillissement. Cela prouve que l'ingénierie des défauts par irradiation d'électrons à haute énergie a le potentiel de fournir des voies de traitement innovantes pour améliorer la stabilité à long terme des performances photovoltaïques HOIPs
During the last eleven years, Hybrid Organic Inorganic Perovskites (HOIPs) materials have emerged as an exciting topic of research for potential application in solar cell technologies due to their outstanding optoelectronic properties and processing advantages. However, HOIPs materials suffer from several drawbacks with, in peculiar, their lack of stability under operational conditions (light, bias, environment…). To improve this stability is one of the biggest challenges to be addressed before commercialization. The general formula for HOIPs is (A1,A2,A3,A4)Pb(X1,X2)3, where the A sites can be occupied by a distribution of 1 to 4 metallic/organic cations and X sites with halide anions. The role of native vacancy defects has been questioned as a possible cause for HOIPs solar cells degradation. The aim of this work is to understand the defect role in long term stability of HOIPs materials for photovoltaics. For this reason, primary defects were introduced in a controlled way via high energy electron irradiation (1MeV) in sets of layers and solar cells (SCs) fabricated using various HOIPs compounds. Those include the photovoltaic HOIPs prototype, MAPbI3 (A1PbX13), and emergent triple or quadruple cation mixed halide HOIPs, (CsMAFA)Pb(I1-xBrx)3 (A3PbX23) or (GACsMAFA)Pb(I1-yBry)3 (A4PbX23). The HOIPs layers are fabricated according to the same procedure as the HOIPs active SC layers and, subsequently, treated in similar conditions. For A1PbX13 and A3PbX23, the solar cells are of the p-i-n structure with organic hole and electron transport layer (HTL/ETL). The HOIPs layers are deposited on the glass/ITO/HTL (PEDOT:PSS) substrate without or with the top ETL layer (PCBM). For A4PbX23, the solar cells are of the n-i-p type with inorganic ETL (TiO2) and organic HTL (Spiro-OMeTAD) layers. The layers are directly deposited on glass without the ETL layer.Positron Annihilation Spectroscopy (PAS) gives direct evidence for native vacancy-type defects and irradiation induced ones in layers of each HOIP compound. The energy dependence of absorbance shows that natural and after irradiation ageing generates different defect populations in each HOIP compound. These populations strikingly also differ depending on the absence or presence of the top ETL layer for the A1PbX13 and A3PbX23 compounds. The defect populations evolve over ageing duration as long as 3 months. The prominent effects of ageing include (i) band gap modification, (ii) tailing of conduction/valence band extrema and (iii) optical absorption via deep subgap electronic levels. Illumination effects under laser also vary with ageing for each HOIP compound. Asymmetric photoluminescence (PL) peaks in each compound under continuous laser illumination reflect that radiative emission involves Gaussian emission rays with energy, FWHM and height evolving with illumination time. The emission transitions involve shallow localized electronic levels in A3PbX23 and A4PbX23 and resonant ones in A1PbX13. These electronic levels are attributed to specifically illumination-induced defect populations. Natural and after irradiation ageing result in PL decay lifetime spectra resolved into one or two exponential decay components. The decay components number and lifetime are strongly affected by the initial production of irradiation defects and HOIPs composition. Such effects last over 3 months at least in A4PbX23. The p-i-n solar cells exhibit most striking irradiation ageing induced photovoltaics performance. The External Quantum Efficiency (EQE versus photon energy) and the photovoltaic performance (I-V under illumination) of the irradiated solar cells have higher values than those in the reference SCs after 6 to 12 months of ageing. This gives evidence that defect engineering via high energy electron irradiation has a potential for providing innovative processing pathways to enhance the long-term stability of HOIPs photovoltaic performance
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Werner, P. O. E. Mathias. "Investigation on HSS milling inserts : cutting edge and surface preparation effect on machinability : the capturing, understanding and structure of the gear manufacturing processes may lead to a dynamic link to design aspects such that more effective and reliable cutting tool system development is acheived /." Stockholm : Industriell teknik och management, Kungliga Tekniska högskolan, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-9942.

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Kuldavletova, Olga. "L'intégration multisensorielle fonctionnelle et la plasticité des réflexes vestibulaires Vestibulo-sympathetic Reflex in Patients With Bilateral Vestibular Loss Influence of Graviceptor Stimulation Initiated by Off-Vertical Axis Rotation on Ventilation Effect of self-motion perception on autonomic control Vestibulo-Ocular Responses, Visual Field Dependence, and Motion Sickness in Aerobatic Pilots." Thesis, Normandie, 2020. http://www.theses.fr/2020NORMC405.

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L’objectif de ce travail de thèse était d’évaluer le rôle du système vestibulaire dans l’homéostasie en relation avec l’orientation.Nous avons évalué les réponses vestibulaires (1) dans une population normale pour évaluer le niveau d’implication des différents systèmes sensoriels dans la régulation cardiovasculaire et respiratoire et (2) dans des populations présentant des informations vestibulaires perturbées : soit des patients avec un déficit vestibulaire bilatéral soit des pilotes de voltiges aérienne.Les résultats indiquent que les informations vestibulaires et celles des gravicepteurs du tronc s’associent pour réguler la réponse respiratoire lors de la rotation à axe incliné selon la gravité (RAIG). La contribution respective des récepteurs vestibulaires et des gravicepteurs dans cette réponse varie en fonction des individus. Une autre étude a testé l’hypothèse selon laquelle la modulation de la réponse cardio-vasculaire par le système vestibulaire peut être influencée par les informations visuelles pendant la RAIG. Les résultats préliminaires de cette étude ont montré que la stimulation RAIG a un effet sur les valeurs moyennes des paramètres cardio-vasculaires. L'effet modulateur de la RAIG sur la pression artérielle a également été démontré. Cette modulation de réponse, et plus particulièrement la phase, variait entre les individus, ce qui peut indiquer la nature neuronale de la modulation observée. Un effet de la stimulation visuelle sur la modulation semble être également présent, mais une analyse plus approfondie est nécessaire pour confirmer ce résultat. Dans une autre étude, il s’est avéré que des patients présentant une déficience vestibulaire bilatérale avaient la même réponse cardio-vasculaire aux changements de position de la tête pendant le protocole « head down neck flexion » que les sujets témoins. Ces résultats indiquent que cette reconstruction du réflexe vestibulo-sympathique semble provenir de sources sensorielles autres que labyrinthiques. Enfin, nous avons étudié les pilotes de voltige aérienne comme modèle de sujets subissant des stimulations vestibulaires intenses et inhabituelles. Nous n'avons pas observé l’habituation vestibulaire attendue lors d’explorations fonctionnelles vestibulaires (RAIG et échelon de vitesse) en comparaison avec des sujets témoins, en revanche les pilotes étaient moins sensibles au mal des transports. Nous suggérons que les pilotes ne développent pas d'habituation vestibulaire comme attendu car ils ont besoin des réponses vestibulaires préservées et non altérées pour maintenir une performance optimum lors des activités de voltige aérienne.Nous concluons que pour générer des réponses en lien avec l’orientation, le système nerveux central intègre les signaux vestibulaires et non-vestibulaires et est sujet à un certain niveau de plasticité en conditions sensorielles altérées. Ce traitement multisensoriel est régulé individuellement, avec un poids variable des informations vestibulaires, en fonction de l'état sensoriel et des exigences liées à l’activité
The aim of this thesis was to specify the role of the vestibular system in the orientation-related homeostasis. We evaluated vestibular responses to changes in orientation in space (1) in normal population to reveal in what proportion different sensory systems are implicated in the generation of the cardio-vascular and respiratory responses, and (2) in populations with altered vestibular afference: bilateral vestibular loss patients and aerobatic pilots.The results indicated that the vestibular system cooperates with trunk graviceptors to evoke respiratory response to changes in orientation during Off-Vertical Axis Rotation protocol (OVAR). The contribution of each sensory source was found to vary between individuals. Another study tested the hypothesis that the vestibular modulation of cardio-vascular parameters can be influenced by visual input during OVAR. Preliminary results from this study have demonstrated that the OVAR stimulation has an effect on the mean cardio-vascular parameters. The modulatory effect of OVAR on the arterial pressure has also been shown. The phases of modulation were varying between individuals which can indicate the neural nature of the observed modulation. The effect of visual stimulation on modulation has been detected, however further analysis is required. In another study, subjects presenting bilateral vestibular loss were shown to have the same cardio-vascular response to changes in the position of the head during Head-Down-Neck-Flexion protocol (HDNF) as normals. This reconstruction of the vestibulo-sympathetic reflex in human seems to originate from the sensory sources other than labyrinthine. Finally, we studied aerobatic pilots as humans experiencing intense and unusual vestibular stimulations. We have not revealed the expected vestibular habituation in the study using the OVAR and EVAR (Earth-Vertical Axis Rotation) stimulations, but were significantly less susceptible to motion sickness. We suggest that the pilots do not develop habituation, as they require unsuppressed responses for a better performance.We conclude that to generate the orientation-related responses, the Central Nervous System integrates the vestibular and non-vestibular signals and is subject to plastic changes in altered sensory conditions, if the response needs to be changed or restored. This multisensory processing is individually tuned, with the variable portion of vestibular impact in this processing, depending on activities, sensory state and the requirements to the response
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Outlioua, Ahmed. "Exploration des cytokines pro-inflammatoires et de l’inflammasome NLRP3 dans les infections intracellulaires : cas de H. pylori et des virus à ARN Gastric IL-1β, IL-8, and IL-17A expression in Moroccan patients infected with Helicobacter pylori may be a predictive signature of severe pathological stages RNA viruses promote activation of the NLRP3 inflammasome through cytopathogenic effect-induced potassium efflux The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling The Role of Optineurin in Antiviral Type I Interferon Production Possible introduction of Leishmania tropica to urban areas determined by epidemiological and clinical profiles of patients with cutaneous leishmaniasis in Casablanca (Morocco)." Thesis, université Paris-Saclay, 2021. http://www.theses.fr/2021UPASL029.

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Helicobacter pylori (H. pylori) est une bactérie qui infecte l’estomac et induit une gastrite inflammatoire, qui peut être chronique et évoluer vers un cancer gastrique. La sévérité de l’infection et son évolution clinique sont associées aux différents facteurs notamment le statut immunitaire de l’hôte. La réponse inflammatoire initiale à l'infection à H. pylori entraîne la sécrétion d'un large panel de cytokines, notamment l'interleukine-1β (IL-1β), l'IL-8 et l'IL-17A. qui semblent jouer un rôle clé dans l'initiation et la progression du cancer gastrique. Parmi ces cytokines, l'IL-1β est une cytokine clé au cours de l’infection à H. pylori dont l’expression est étroitement associée à l'inflammation gastrique et à la carcinogenèse. La production de cette cytokine dépend de l'activation de l'inflammasome, en particulier l'inflammasome NLRP3. Ce dernier, responsable de l’activation des processus inflammatoires, est essentiel pour le maintien de l'homéostasie contre diverses infections pathogènes telles les infections bactérienne et virale.L’objectif général de ce travail est i) d’étudier l’expression et le polymorphisme des gènes de cytokines comme IL-1β, IL-17 et IL-8 chez des patients marocains infectés par H. pylori. ii) explorer l’activation de l'inflammasome NLRP3 par H. pylori et déterminer les mécanismes impliqués dans l'activation de ce complexe par des virus à ARN ; connus comme des activateurs définis de NLRP3.Nos résultats ont souligné une prévalence élevée de H. pylori et ont mis en évidence une signature cytokinique : elle peut prédire la métaplasie au cours de la progression de l'infection à H. pylori impliquant une diminution de l’expression de l'IL17A dans l’antre et une augmentation de l’expression de l'IL-1β dans le fundus. Plus particulièrement, les polymorphismes génétiques de l’IL-1β (IL-1β -31 et -511) ne semblent pas influencer l’expression de l’IL-1β de manière significative.Au regard des difficultés rencontrés pour l’isolement et la culture de H. pylori, nous avons utilisé le LPS de H. pylori pour stimuler l’inflammasome. Nos résultats montrent que la transfection des cellules in vitro par le LPS bactérien induit la production de l’IL-1β qui semble être modulée par la caspase 4, NOD1 et NOD2. Par ailleurs, bien qu’il soit clairement établi que les virus à ARN induisent l’activation de l’inflammasome NLRP3, les mécanismes par lesquels ces virus induisent la production d'IL-1β ne sont pas bien compris et restent à confirmer. Les résultats de cette partie du travail ont montré que la réplication des virus à ARN cytopathogènes tels que le virus de la stomatite vésiculaire (VSV) ou le virus de l'encéphalomyocardite (EMCV) induit une mort cellulaire lytique conduisant à un efflux de potassium qui déclenche l'activation de l'inflammasome NLRP3. Ainsi, les virus à forte capacité de réplication et qui ont un effet cytopathique sont capables d'induire l'activation de la caspase-1 conduisant à la production d'IL-1β. A l'inverse, les virus qui induisent une très bonne réponse IFN de type I sont de très mauvais inducteurs de l'inflammasome NLRP3.Une meilleure compréhension de l’activation de l’inflammasome pourrait aider dans la mise au point de stratégies thérapeutiques ciblées utilisables dans la lutte contre les infections bactérienne et virale.Mots clés : Helicobacter pylori, inflammation, inflammasome NLRP3, IL-1β, virus à ARN
Helicobacter pylori (H. pylori) is a bacteria that infects the stomach and induces inflammatory gastritis, which can be chronic and progress to gastric cancer. The severity of the infection and its clinical course are associated with various factors including the immune status of the host. The initial inflammatory response to H. pylori infection results in the secretion of a wide range of cytokines, including interleukin-1β (IL-1β), IL-8 and IL-17A. which appear to play a key role in the initiation and progression of gastric cancer. Among these cytokines, IL-1β is a key cytokine during H. pylori infection whose expression is associated with gastric inflammation and carcinogenesis. The production of this cytokine depends on the activation of the inflammasome, in particular the NLRP3 inflammasome. The latter, responsible of the activation of inflammatory processes, is essential for the maintenance of homeostasis against various pathogenic infections such as bacterial and viral infections.The general objective of this work is i) to study the expression and polymorphism of genes for cytokines such as IL-1β, IL-17 and IL-8 in Moroccan patients infected with H. pylori. ii) explore the activation of the NLRP3 inflammasome by H. pylori and determine the mechanisms involved in the activation of this complex by RNA viruses; known as defined activators of NLRP3.Our results underlined a high prevalence of H. pylori and demonstrated a cytokine signature: it can predict metaplasia during the progression of H. pylori infection involving a decrease in IL17A expression in the antrum and increased expression of IL-1β in the fundus. In particular, the genetic polymorphisms of IL-1β (IL-1β -31 and -511) do not appear to influence IL-1β expression significantly.In view of the difficulties encountered in isolating and culturing H. pylori, we used LPS from H. pylori to stimulate the inflammasome. Our results show that the transfection of cells in vitro with bacterial LPS induces the production of IL-1β which appears to be modulated by caspase 4, NOD1 and NOD2. Furthermore, while it is clearly established that RNA viruses induce activation of the NLRP3 inflammasome, the mechanisms by which these viruses induce IL-1β production are not well understood and remain to be confirmed. The results of this part of the work showed that the replication of cytopathogenic RNA viruses such as vesicular stomatitis virus (VSV) or encephalomyocarditis virus (EMCV) induces lytic cell death leading to an efflux of potassium which triggers activation of the NLRP3 inflammasome. Thus, viruses with a high replication capacity and which have a cytopathic effect are capable of inducing the activation of caspase-1 leading to the production of IL-1β. Conversely, viruses which induce type I IFN response are very poor inducers of the NLRP3 inflammasome.A better understanding of the activation of the inflammasome could help in the development of targeted therapeutic strategies for use in the fight against bacterial and viral infections.Key words: Helicobacter pylori, inflammation, NLRP3 inflammasome, IL-1β, RNA virus
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32

Achuo, George. "Partner satisfaction and renewal likelihood in consumer supported agriculture (CSA) : a case study of The Equiterre CSA network." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=19555.

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33

Kaddoura, Malak Ehsan. "Sell in May Effect: a real deal or a fake one ?" Master's thesis, 2017. http://hdl.handle.net/1822/46484.

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Dissertação de mestrado em Finanças
In an efficient market, information is reflected on market prices, and consequently prices should follow a random walk, and their changes should be unpredictable (Fama, 1965a). The aim of this research is to test the efficient market hypothesis. In particular, this dissertation investigates the weak-form market efficient hypothesis through analyzing the existence of the ”Sell in May and Go Away” calendar anomaly (also known as the Halloween Effect). The data set consists of monthly stock returns for value-weighted indices of 25 international countries. We follow a regression analysis methodology to: test for the existence of the Halloween effect in both developed and emerging markets, test if the Halloween effect is a January effect in disguise, and test if crashes affects the results. The results show that the Sell in May effect exists in 9 countries out of the studied 25 countries, and that the Sell in May effect is not simply a January effect. However, controlling for crashes makes the Sell in May anomaly to disappear. Finally, an evaluation of the performance of both the Halloween trading strategy in comparison with the Buyand-Hold strategy is made. The result show that the former is more profitable in 9 out of the 25 countries even after amending transaction costs.
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34

Santos, António Maria Barahona da Silva Martins dos. "Sell in May and go away : adage or self-fulfilling prophecy ?" Master's thesis, 2013. http://hdl.handle.net/10400.14/13831.

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The purpose of this paper is to explore the “Sell in May” effect, which is related to the fact that financial markets seem to provide positively significant returns from November to April and not significant or negatively significant returns from May until October. The Sell in May effect is present in 30 out of 37 indexes, using a sample of 37 country indexes from 1970 to 2011. All sectors of activity are consistently affected by this seasonal pattern, being the effect stronger in production related sectors. The effect is largely felt in high market capitalization companies and less in companies with high dividend yield, being that there is not any clear pattern regarding Price-Earnings ratio. Furthermore, a strategy developed taken into account the “Sell in May” effect outperforms the benchmark, providing higher risk-adjusted returns for an investor.
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35

Zhang, Jia Hong, and 張嘉宏. "The Effect of Voluntary Sell-off Announcements." Thesis, 1996. http://ndltd.ncl.edu.tw/handle/86860084845724159537.

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36

Chen, Pei-ju, and 陳姵汝. "the effect of reverse takeover on sell company in Taiwan." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/55406565185156371810.

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碩士
國立中央大學
財務金融學系
102
There are a few studies examining the market reactions to the reverse takeovers in U.S and Taiwan. Because the shell company in Taiwan is a little different from in U.S. This paper examines the reverse takeover in Taiwan. In this paper, I find a sample of 79 shell companies in the period from 1990 to 2012. This paper discusses five dimensions about the shell companies 3 years before and after reverse takeover. Dimensions are company scale, the ability of asset management, profitability, financial leverage, and opportunities of growth respectively.
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37

Chang, Chia-Yu, and 張家毓. "The Effect of Data Input Order on Self-Organizing Map learning." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/n7w98m.

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38

Chung, Sung Gon Barron Orie E. "Hedge funds and sell-side research the effect of hedge funds' stock positions on analysts' recommendations /." 2009. http://etda.libraries.psu.edu/theses/approved/PSUonlyIndex/ETD-4277/index.html.

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39

Chan, Shu-Nien, and 詹淑年. "The Effect of RMB exchange rate fluctuation on Taiwan’s Financial Stock and Buy/Sell of Institutional Investors." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/20713746660636385402.

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碩士
淡江大學
財務金融學系碩士在職專班
104
In recent years, Taiwan RMB deposit expansion is very rapid.It has exceeded 300 billion yuan until November 2014, and becomes the only time for the US dollar is all foreign currency deposits rank in the second place. It is also the global offshore RMB center only in Hong Kong''s second largest capital pool. But the people''s Bank of China in 2015 laissez faire RMB to depreciate heavily, tipping the global financial market volatility, lead to stocks and the stock plunged, and plunged the Taiwan stock market in financial stocks decline in the deep. So the study in January 4, 2010 to January 13, 2016 (a total of 1,483, 29 domestic files listed financial stocks) as samples, using PSTR (panel smooth transition regression model) model to investigate the RMB exchange rate change on the influence of Taiwan financial stocks, shares and institutional investors'' behavior. Empirical results show that prior to March 13, 2012, legal person of financial stocks traded super amount and the financial returns of stock price is not significantly affected, prior to this date the RMB exchange rate on financial stocks had no effect; and after March 13, 2012, the RMB exchange rate on financial stocks have significant negative to the influence that the RMB exchange rate appreciation in recent years the domestic financial sector the importance more. In addition, this thesis empirically found that when the RMB appreciation (depreciation) value more than 0.0582%, legal to buy (sell) super financial stocks return significantly rise (fall), and corporation will actively traded financial stocks behavior, and the behavior of sensitivity, to investment trust, dealers times and foreign minimum. The reason but investment trust corporation performance due to the pressure, the operation tendency in short-term trading, chasing Shadie. Therefore, investment trusts adjust mostly the financial stock behavior due to RMB appreciation (depreciation) value in three institutional investors.
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40

Hsieh, Han-Hsien, and 謝瀚賢. "When Do Financial Institutions Tend to Buy or Sell Real Estate? The Market Timing and Signaling Effect." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/65209880826727981246.

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碩士
元智大學
財務金融學程
99
In Taiwan, real estate investment is a important way to make profit for insurance companies. This research investigates the trading behavior of all financial institutions in Taiwan which includes insurance firms and subsequent stock performance. In particular, the main purpose of this study is to examine whether Taiwanese financial institutions prefer to sell real estate during good time of real estate market, and buying real estate during bad time. If firms can timing the trading, whether this active release good news to investors so stock price response positively according to signal effect? In the meanwhile, I also examine the impact of the types of financial institutions, the purpose of trading real estate, and the relationship between buyer and seller, which will affect firms’ market-timing ability. The empirical result is consistent with the hypothesis. For financial institutions, especially for commercial banks, there are significant evidences to verify firms have good market-timing ability to trade properties. Further, through event study, the result shows that there are positive and significant signaling effects on stock price for those firms who can time the market successfully; however, it only happens when firms buy properties in the bad time. Besides, the result of event study shows that firms who trade with the non-related contract party will have better timing ability and stock performance than other firms who trade with the related one. Nevertheless, the results for firms who trade with different purposes are inconsistent with our hypothesis.
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41

Lin, Chi-Shiang, and 林啟翔. "Using Self Organizing Map to Determine Individual Stock Information Effect on Its Volatility." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/xk24ty.

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碩士
國立臺灣大學
財務金融學研究所
105
Volatility prediction is an important issue in the financial market. Since many factors will influence the volatility, it still cannot be predicted accurately. Most research agree that the volatility process has ARCH effect, and many methods have be proposed to describe the volatility process. This paper gives a new aspect of volatility. Our work uses the self organizing map, an artificial neural network method to verify the information type and put this information into the GJR GARCH model, which proposed by Engle and Victor. By using this model, the volatility of individual stock can be predicted better than using the simple GJR GARCH model. with some type of asset. And the result of this model also has similar result with Chen and Ghysels (2011)[1], which implies that some type of information will decrease the mean of the future volatility. Our raw data is the assets’ realized volatility in Taiwan to be our data, and found that not all of the assets are suitable for this model but three assets are. Hence, in conclusion we propose a method to detect what kind of data is suitable for this model. It also gives the criteria to determine the time for changing pricing volatility. Moreover, this model gives you a methodology for testing the results given from artificial neural network.
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42

Lee, Jen-Chun, and 李仁君. "The nonlinear study of the effect of the net buy/sell position of three institutional investors on the Stock returns." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/17906731425699363154.

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碩士
淡江大學
財務金融學系碩士在職專班
97
By analyzing the daily open interest from major institutional investors(including FINI, Investment Trust Companies and Futures Proprietary Merchants and Securities Dealers) and the corresponding closing price of TAIEX(Taiwan Stock Exchange Capitalization Weighted Stock Index), this study probes into whether a net buy/sell position by major institutional investors in futures market has nonlinear impact on rate of return on stock price. In methodology, first we employ unit root test on the samples, and then utilize the Smooth Transition AutoRegression(STAR) model, Granger and Teräsvirta(1993)and Teräsvirta(1994), to verify the nonlinear impacts between (1)net position by Investment Trust Companies in futures market for current period, (2)net position by FINI in future market for current period, and (3)net position by Dealers in future market for the last 3 periods and the rate of return on stock price, under different levels of transformation variables. According to our empirical research, the Dealers has the greatest influence on the rate of return on stock price, followed by FINI and Investment Trust Companies. A good explanation might be that dealers tend to be arbitrary in making investment decisions given the fact that their performances are basically measured by profit making. In our model, their net position in futures markets has positive and significant impact on the rate of return on stock price at all level of transformation variables. FINI, dragged by their vast holdings, however focus more on portfolio allotment and risk diversification. The policy of giving higher priority to controls of risks leads to a passive, compared to that of dealers’, strategy of investment. As a result, domestic investors used to follow the trading strategy of FINI may be misled by solely leveraging FINI’s position in futures market. As for Investment Trust Companies, they are relatively conservative in futures trading and hence have mere influence on rate of return on stock price, due to restrictions on regulations and fund types.
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43

Chen, Chiu Hua, and 陳秋樺. "The effect of Chinese herbs on endothelial cell migration may be mediated through MMP-2." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/98722770541316340340.

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碩士
慈濟大學
醫學研究所
96
In the process of angiogenesis, the MMP-2 plays an important role in basement membrane degradation to facilitate cell migration. Especially in tumorgenesis, it has been shown that MMP-2 is an important “angiogenic switch”. It has important regulation in endothelial cell migration. Now I am interested in evaluating the hypothesis that Chinese herbs that affect endothelial cells migration may be mediated though MMP-2. The MMP-2 activity is assayed by SDS-polyacrylamide gel with gelatinas substrate. The conditioned medium collected from cells treated with Chinese herbs was separated by electrophoresis. After staining with Coomassie Blue, The degradation of gelatin, as indicated by the blank gel, was estimated by reading the density of the blank area. CPAE(calf pulmonary artery endothelial cells ) in PBS were treated with herbs in various concentrations for 6 hr. Our results showed that 40 herbs had various potencies to inhibit MMP-2 activity: in the group that enhances migration, 4 herbs enhanced, one inhibited, and 4 with no effect; in the group that with no effect, 1enhanced, 2 inhibited, and 6 with no effect; and in the group that inhibits migration, 1 enhanced, 11 inhibited, and 10 with no effect. These results suggest that there is no one simple functional correlation with Chinese herbs can be identified, probably due to its multiconsituents nature.
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44

LIN, HSUAN-HSIU, and 林宣秀. "The Information Transmission Effect and Influence of Dealer’s Net Buy and Net Sell (Hedging) Shares on Stock Prices of (Put) Warrant." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/u5h2u4.

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碩士
輔仁大學
金融與國際企業學系金融碩士在職專班
105
Innumerable domestic market research and analyses on institution holdings and ownership of call (put) warrants have been conducted; nevertheless, the analyses rarely center on the posterior direct impacts of investor’s call (put) warrant transactions on prices of underlying stocks because of the limitations on information disclosure. Consequently, this study aims to the information transmission effect and influence of dealer’s net buy and net sale (hedging) shares on stock prices of call (put) warrants after the competent authorities differentiated proprietary trading from hedging trading on net buy/ net sale as of August 31st, 2016; It is expected,through institution holding and ownership of call (put) warrants reflected by dealer’s net buy and net sale (hedging) shares, to further probe into whether herding effects, feedback trading, cascading, andmomentum are generated by prices of linked underlying stocks. This study analyzes the herding effect model, feedback trading and cascading, and the herding and rate-of-return momentum model in respect of dealer’s net buy and net sale (hedging) shares and corresponding rates of return for stock prices through acquired data of the sampling period; Furthermore, Granger Causality Test will be adopted to examine whether changes in dealer’s net buy and net sale (hedging) shares influence rates of return for prices of underlying stocks or whether rates of return for prices of underlying stocks influence dealer’s net buy and net sale (hedging) shares. In addition, Event study is employed to examine whether there is any likelihood that average abnormal returns or average cumulative abnormal returns for posterior stock prices arise after the abnormal volume of dealer’s net buy and net sale (hedging) shares appears. The result of this empirical study indicates positive heading effects between dealer’s net buy and net sale (hedging) shares and rates of return for prices of underlying stocks of the OTC markets. The empirical model also reveals that the general explanatory power of the model strengthens when the OTC-listed company is smaller-scaled in market value. Further, Granger Causality Test shows that, despite possible causal relationships among partial samples, the general causal relationship accounts for low percentage, The feedback trading is insignificant between dealer’s net buy and net sale (hedging) shares and rates of return for prices of underlying stocks. Notwithstanding, in cascading, the reverse investment in accordance with dependent variables of antecedent dates is witnessed in the underlying call (put) warrants of the OTC markets; Furthermore, the study indicates that the momentum which dealer’s net buy and net sale (hedging) shares and rates of return for prices of underlying stocks onbetween antecedent and subsequent periods is not significant. Lastly, the result of the event study reveals that, in the OLS standard analysis, negative average cumulative abnormal returns are generated after the events specified in this study appear in dealer’s net buy and net sale (hedging) shares.
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45

Van, Niekerk Sonja. "The effect prophylactic escherichia coli nosodes may have on alleviating enteric disease in pre-weaned piglets." Thesis, 2009. http://hdl.handle.net/10210/2594.

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46

Jiang, Lin-Yu, and 蔣玲鈺. "An Empirical Study of Stock Holding Preference of Three Primary Professional Investment Institutions and the Monday Effect of Net Buy-and-Sell." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/68069284975142874482.

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碩士
淡江大學
管理科學研究所碩士班
95
Three primary professional institutional investors in Taiwan are categorized as Foreign Investor, Investment Trust and Security Dealer, according to their sources of funds. Their investment decisions are important for the public in the Taiwan stock market. In addition, net buy-and-sell information of institutional investors is also a major focus for the public. However, there are very few academic studies document observations regarding the issue of the Monday effect. The main purpose in this study is to investigate the stock holding preferences of the three primary professional institutional investors and the Monday effect of net buy-and-sell.   This study employs two regression models and the Panel Data to examine the two major objectives of the three primary professional institutional investors. Using a sample of firms listed in Underlying Stocks of Taiwan 50 Index from Taiwan Economic Journal(TEJ) over the period of 2002 to 2005, this study explores five empirical results: 1.Foreign investors show a preference for large firms, firms with high sales growth ratio、low book-to-market ratio and low dividend yield. 2.Investment trusts prefer firms with high current ratio、high margin buying ratio、low book-to-market ratio、high turnover ratio and large companys. 3.Security dealers are inclined to adopt the high risk strategy and prefer firms with high debt ratio. 4.The three primary professional institutional investors have different stock holding strategies. Foreign investors are concerned with the financial characteristics of firms. Investment trusts show a preference for firms with high current ratio. Security dealers pay attention to the technical analysis while selecting stocks. 5.Only foreign investors and investment trusts show the Monday effect with significant negative returns.
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47

Nunes, Tylah. "You may not be as smart as you think : an alternative account of the Dunning-Kruger effect." Diss., 2014. http://hdl.handle.net/2263/42444.

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Perception of abilities plays an important role in informing one’s decisions at times and often in forming one’s self perception. The Dunning-Kruger effect is a fascinating and empirically observable bias in which top performers tend to make more accurate estimations of their ability than bottom performers. The current theory states that the effect is caused by top performers possessing greater metacognitive ability than bottom performers. There have been many alternative theories and explanations proposed to explain the observed Dunning-Kruger effect. The current study is the first to test whether top and bottom performers base their predictions on inflated preconceived notions of ability, rather than their metacognitive ability. This theory proposes that if top and bottom performers both based their predictions of performance on their preconceived notions of ability it would create a Dunning-Kruger effect. This presupposes that that both top and bottom performers make above average estimates of performance as they hold preconceived notions of above average ability. Thus, top performers’ predictions of performance would be most accurate as their performance would be above average, whereas bottom performers would most overestimate their performance as their performance would be below average. The intention of this study was, thus, to assess whether either top or bottom performers based their predictions of performance on preconceived notions of ability or using metacognitive ability. A total of 97 university students were divided into two groups and given an identical test, one group containing 49 participants were told the test measured Logical Thinking and the remaining 48 participants were told the test measured Computational Mathematics. After completing the test, which was a 23 item preparatory test for the LSAT, participants were asked to estimate their ability in the domain being assessed, their performance relative to their peers and their score out of 23. A t-test was used to compare the two groups and it was found that the Logical Thinking and Computational Mathematical group made significantly different predictions of ability and therefore held significantly different preconceived notions of ability. Further t-tests were used to compare the estimates of ability and predictions of performance of the two groups of top and bottom performers. A significant difference was found between the two groups of top performers’ prediction of ability. However, there was no significant difference between any of the other scores of the two groups of top and bottom performers. Therefore, the alternative theory that top and bottom performers base their predictions of performance on preconceived notions of ability was found to be invalid. Therefore, the current theory which states that top performers’ superior metacognitive ability allow them to make more accurate estimates of performance than bottom performers is still the best account for the Dunning-Kruger effect.
Dissertation (MA)--University of Pretoria,2015.
Psychology
Unrestricted
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48

Lu, Yi-Ping, and 呂怡萍. "A Study of the Effect of the Net Buy/Sell of Three Institutional Investors on Taiwan 50 Index and the Taiwan Stock Index." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/43192720801512530834.

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碩士
淡江大學
財務金融學系碩士在職專班
98
This study investigates the nonlinear effects of the total net buy/sell amount of three institutional investors (3I) on Taiwan weighted stock index (TWSI) and Taiwan 50 index (TW50). We further analyze the individual impact of the net buy/sell of three institutional investors (including foreign investor, mutual fund and security dealer) on TWSI and TW50, respectively. We first employ unit root test on each variable considered, and then utilize the smooth transition regressive (STR) model elaborated by Granger and Teräsvirta(1993) and Teräsvirta(1994) to investigate the nonlinear effects by setting 3I as transition variables. Our empirical results first find that there has no non-linear effect of 3I on TWSI. The further linear regression shows that the impact of the net buy/sell of foreign investor on TWSI is not significant, however, the impact of net buy/sell of mutual fund and security dealer on TWSI are significant positively and negatively, respectively. Moreover, the total net buy/sell amount of three institutional investors has significant and positive impact on TWSI. On the contrary, testing for the linearity finds a non-linear effect of 3I on TW50 with 3-lag model. The further testing for the STR model shows that when 3I is less than the threshold value of NT$272,479,000, the significance and direction of the impact of the net buy/sell of each institutional investor on TW50 are exactly the same as the previous findings as on TWSI. However, when 3I is higher than the threshold value of NT$272,479,000, there is no significant impact showed for the net buy/sell of each institutional investor on TW50. Finally, the empirical result shows that the transition coefficient is approaching to zero, which implies that, even there exists a non-linear phenomenon with an ESTR specification, the relationship between the 3I and TW50 is nearly linear.
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49

CHOU, YING-YU, and 周映妤. "Water Extract of Gastrodia elata Bl. May Have Antidepressant Effect via Enhancing Neuroplasticity in Chronic Mild Stress Model." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/48469790254451412054.

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碩士
國立臺灣大學
食品科技研究所
103
According to the World Health Organization(WHO) statistics in 2002, major depressive disorder was defined as one of the three major diseases in 21th century and over 87% suicide victims has mood disorder. In Taiwan, there is over 8.9% population has the depression. Therefore, it is necessary for investigative the pathophysiology of depression and the antidepressant therapeutics. However, depression pathology is multifactorial, which includes monoamine dysregulation, HPA(Hypothalamic–pituitary–adrenal)dysfunction, chronic inflammation and neuroplasticity reduction. The antidepressant used in clinics now brings a lot of side effects. Thus, looking for the alternative therapy and prevention strategy for depression are very important issues. One of animal models used to study depression is the chronic mild stress model .It is a well-known animal model which has high-validity, mimics the real human stressed environment. Recently, Gastrodia elata Blume has shown anxiolytic, mood and memory enhancing effects. In previous study, the water extract of Gastrodia elata Blume (WGE) has antidepressant-like effects in the forced swimming model. Therefore, the aim of this project is to investigate the antidepressant effects of Gastrodia elata Blume in the chronic mild stress model. The results of behavior showed that CMS group markedly decreased in sucrose intake in week 4 comparing to normal group. The group of WGE medium dose and low dose had significantly different with CMS group separately in week 5 and week 6. In the open field test, CMS showed significantly lower than normal and WGE treatment group in crossing in week 4 and week 5. In the rearing part, CMS also had significantly different with normal in week 4 to week 6, even with fluoxetine and L-WGE in week 6. The result of IHC (immunohistochemistry)showed that CMS group was lower number of cell survival and proliferation than normal group. M-WGE showed significantly higher than CMS group in cell survival. In the WGE related antidepressive pathway: Slit-robo, Slit-1 showed that chronic mild stress truly had higher level than normal and WGE treatment in hippocampus. In conclusion, WGE may had antidepressive effect though reverse neuroplasticity in chronic mild stress model.
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50

Tsai, Meng-Tse, and 蔡孟哲. "Comparison of the Effect of Net Buy-Sell Position of Foreign Investor on the Stock Prices of Apple and HTC after IPO of iPhone5." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/11629095576470892990.

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Abstract:
碩士
淡江大學
財務金融學系碩士班
101
This study is based on the trading of foreign investors in stocks over the amount to be interpreted as a threshold variable, the other control variables are Taiwan Weighted Stock Index, crossover the leading stock price and shares of foreign ownership of the concept stock.Explore whether the effect is nonlinear between the concept stocks of iPhone5 and HTC by the trading over of iPhone5 stocks of foreign investors after the listing of iPhone5. First, on the research methods ,the sample data of the paper do the unit root test whether the steady state test data information , LLC tests ,IPS test and ADF-Fisher test used in this study, then using Smooth Transition AutoRegression proposed by Gonza''lez, Terasvirta and van Dijk , to explore foreign stocks trading on the amount over、Taiwan weighted Stock Index、crossover leading stocks and shares of foreign ownership of concept stocks of HTC and iPhone5 whether stocks of non-linear effects discussed in the difference of the conversion variable model.
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