Relevant bibliographies by topics / Selenium-Enriched yeast

Academic literature on the topic 'Selenium-Enriched yeast'

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Published: 27 July 2024
Last updated: 29 July 2024

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Journal articles on the topic "Selenium-Enriched yeast"

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ANIZOBA, N. W., N. E. IKEH, C. EZENWOSU, F. U. UDEH, and N. S. MACHEBE. "Effect of dietary organic selenium on growth performance, antioxidant status and carcass characteristics of broiler chicken reared in the tropics." Indian Journal of Animal Sciences 94, no. 6 (June 13, 2024): 553–59. http://dx.doi.org/10.56093/ijans.v94i6.144852.

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An experiment was conducted to determine the effect of dietary organic selenium inclusion on growth performance, antioxidant capacity, selenium retention and carcass characteristics in broiler chicken. Day-old broiler birds (160) were distributed randomly into four equal groups (T1, T2, T3 and T4) comprising of four replicated pens with ten birds in each. Different treatment groups of birds were designated as T1 (Basal diet without selenium-enriched yeast), T2 (Basal diet with 0.50 mg/kg selenium enriched yeast), T3 (Basal diet with 1.00 mg/kg\ selenium enriched yeast) and T4 (Basal diet with 1.50 mg/kg selenium enriched yeast) for 56 days. The results revealed that final body weight, weight gain and feed conversion ratio were significantly enhanced for birds in T2 at both stages than other groups. T4 group showed highest glutathione peroxidase, catalase, superoxide dismutase and selenium concentration with lower malondialdehyde concentration compared to birds receiving other treatments. Carcass traits such as live weight and dressed weight significantly improved in T2 whereas relative weights and lengths of organs increased as level of organic selenium increased. Therefore, it can be concluded that adding 1.50 mg/kg selenium yeast enhanced growth, oxidative status, selenium deposition, carcass and organ traits without having a negative impact on the birds’ physiological state.
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Yoshinaga, Masafumi, Stephanie How, Damien Blanco, Ian Murdoch, Matteo Grudny, Samantha Powers, Nelson Molina, Barry Rosen, and Aaron Welch. "Directed Evolution of Saccharomyces cerevisiae for Increased Selenium Accumulation." Microorganisms 6, no. 3 (August 6, 2018): 81. http://dx.doi.org/10.3390/microorganisms6030081.

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Selenium-enriched yeast (selenium yeast) are one of the most popular sources of selenium supplementation used in the agriculture and human nutritional supplements industries. To enhance the production efficiency of selenium yeast, we sought to develop a method to identify, and ultimately select for, strains of yeast with enhanced selenium accumulation capabilities. Selenite resistance of four genetically diverse strains of Saccharomyces cerevisiae was assayed in various conditions, including varying carbon sources, nitrogen sources, and phosphate amounts, and they were correlated with selenium accumulation in a commercially relevant selenium-containing growth medium. Glycerol- and selenite-containing media was used to select for six yeast isolates with enhanced selenite resistance. One isolate was found to accumulate 10-fold greater selenium (0.13 to 1.4 mg Se g−1 yeast) than its parental strain. Glycerol- and selenium-containing medium can be used to select for strains of yeast with enhanced selenium accumulation capability. The methods identified can lead to isolation of industrial yeast strains with enhanced selenium accumulation capabilities that can result in greater cost efficiency of selenium yeast production. Additionally, the selection method does not involve the construction of transgenic yeast, and thus produces yeasts suitable for use in human food and nutrient supplements.
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Li, Benjiao, Song Li, Binrong Ma, Yong Jing, Zheming Zhang, Zhijia Li, and Dequan Zeng. "Research progress on the safety evaluation of selenium enriched yeast." E3S Web of Conferences 185 (2020): 04011. http://dx.doi.org/10.1051/e3sconf/202018504011.

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Selenium-enriched yeast has the physiological functions of improving immunity, anti-oxidation, liver protection, lipid-lowering and anti-cancer. Currently, it is widely used as an organic selenium supplement to prevent diseases of livestock and poultry and aquatic animals, and increase the rate of littering and egg production rate of poultry, reduce the mortality of fish and other aquatic animals, and promote the growth of livestock and poultry. This article reviews the acute toxicity, genotoxicity and subchronic toxicity of selenium-enriched yeast, in order to provide a reference for the safe application of selenium-enriched yeast.
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Xiaoguang, Ge, Wang Dahui, Wei Gongyuan, Nie Min, and Shao Na. "Improvement of Physiological Characteristic of Selenium-Enriched Candida utilis with Amino Acids Addition." Biotechnology Research International 2011 (September 19, 2011): 1–7. http://dx.doi.org/10.4061/2011/238456.

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The effects of amino acids addition on cell growth, glutathione biosynthesis, glutathione distribution, and the intracellular oxidation-reduction environment of Candida utilis SZU 07-01 during selenium enrichment were investigated in this study. Most amino acids under appropriate concentrations have positive effects on cell growth of the yeast strain, except for phenylalanine and proline, compared with the control without amino acid addition. The bioconversion of selenite to organic selenium induced the reduction of glutathione synthesis and intracellular distribution of glutathione. However, amino acids including cysteine, glutamine, glutamic acid, isoleucine, leucine, and tyrosine could effectively promote the selenium-enriched yeast to elevate glutathione production, especially increasing the intracellular glutathione content. Moreover, addition of these six different amino acids apparently decreased malondialdehyde concentration and recovered the normal intracellular redox environment of the selenium-enriched C. utilis SZU 07-01. The improvement of physiological characteristic of the selenium-enriched yeast by increasing intracellular glutathione content and lowering malondialdehyde content will undoubtedly help to widen application of selenium-enriched yeast as food or feed additives.
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Esmaeili, Saeideh, and Kianoush Khosravi-Darani. "Selenium-Enriched Yeast: As Selenium Source for Nutritional Purpose." Current Nutrition & Food Science 10, no. 1 (March 31, 2014): 49–56. http://dx.doi.org/10.2174/157340131001140328115753.

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Oliveira, A. F., J. Landero, K. Kubachka, A. R. A. Nogueira, M. A. Zanetti, and J. Caruso. "Development and application of a selenium speciation method in cattle feed and beef samples using HPLC-ICP-MS: evaluating the selenium metabolic process in cattle." Journal of Analytical Atomic Spectrometry 31, no. 4 (2016): 1034–40. http://dx.doi.org/10.1039/c5ja00330j.

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Kieliszek, Marek, Anna Maria Kot, Kamil Piwowarek, and Stanisław Błażejak. "Accumulation of Selenium in Candida utilis Growing in Media of Increasing Concentration of this Element." Applied Sciences 10, no. 4 (February 20, 2020): 1439. http://dx.doi.org/10.3390/app10041439.

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Selenium is considered an essential component of all living organisms. Studies on the enrichment of yeast cells with selenium, using the ability of cell biomass to bind this element, are being reported more and more. Yeast cultures were cultivated in YPD medium enriched with Na2SeO3 salts for 72 h at 28 °C on a shaker utilizing reciprocating motion. Selenium in cell biomass was determined with the use of ICP–MS. It was observed that the addition of selenium to the experimental medium (in the range of 4–100 mg/L) increased the content of this element in the yeast cell biomass. During the extension of cultivation time, the number of yeast cells and biomass yield exhibited a decreasing trend. Based on the obtained results, it was concluded that yeast cells exhibited the ability to accumulate selenium in both logarithmic and stationary growth phases. The dose of 20 and 30 mg/L of selenium in the culture medium meets the expectations in terms of both the content of selenium bound to yeast cells (1944 ± 110.8 μg/g dry weight) under 48-h cultivation. The obtained results confirmed that the Candida utilis ATCC 9950 strain exhibits the ability to bind selenium, which means that the biomass of these yeasts may be used as a natural source of selenium in the diet of humans and animals.
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Ševčíková, S., M. Skřivan, G. Dlouhá, and M. Koucký. "The effect of selenium source on the performance and meat quality of broiler chickens." Czech Journal of Animal Science 51, No. 10 (December 5, 2011): 449–57. http://dx.doi.org/10.17221/3964-cjas.

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The effect of dietary supplementation of selenium in an organic form on performance, carcass traits and selenium content in tissues of broiler cockerels Ross 308 was studied. The soya-wheat-maize diet contained 50 mg vitamin E/kg. The experiment was conducted on 810 straight-run broiler cockerels randomly divided into 3 groups: group I – control, without selenium supplement; experimental group: II – 0.3 mg Se/kg, Se-enriched yeast was applied as a Se source; III – 0.3 mg Se/kg, Se-enriched alga Chlorella as a Se source. The broiler chickens were slaughtered at 42 days of age. In performance traits higher (P ≤ 0.05) live weight of broiler chickens was recorded in the experimental groups (II – 2 430.6 g and III – 2 425.2 g). There were no significant differences between the groups in feed conversion and mortality. Se-enriched alga had the best feed conversion, and selenium supplementation slightly increased mortality in both experimental groups. No significant differences between the groups were found out in carcass traits and dressing percentage. The content of selenium in breast and thigh muscle, feathers and excrements increased (P ≤ 0.05) in both experimental groups compared to the control group. Higher values in breast and thigh muscle and in feathers were measured in the group supplemented with selenium from Se-enriched yeast, also in comparison with the group supplemented with selenium from Se-enriched alga Chlorella. The broiler chickens receiving Chlorella had a higher (P ≤ 0.05) selenium content in excrements compared to the group with Se-enriched yeast. The selenium concentration in liver was higher (P ≤ 0.05) in both experimental groups compared to the control. The supplement of selenium from Se-yeast and Chlorella in the diet for broiler chickens increased the microelement concentration in muscle.    
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Svoboda, Martin, Zdeněk Fajt, Tomáš Baňoch, Josef Drábek, and Alena Saláková. "The Use of Selenium Enriched Enterococcus faecium as an Alternative Selenium Source for Growing-finishing Pigs." Acta Veterinaria Brno 79, no. 4 (2010): 511–17. http://dx.doi.org/10.2754/avb201079040511.

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The aim of the study was to evaluate the effect of the feeding of selenium enriched Enterococcus faecium on selenium concentrations in muscle tissue and on meat quality indicators in finishing pigs. Groups of pigs fed Se-enriched E. faecium (n = 12), sodium selenite (n = 12) and Se-enriched yeast (n = 12) were used in the study. The tested feed mixtures were fed for a period of 3 months before the pigs were slaughtered. The selenium concentrations in muscle tissue achieved by the use of Se-enriched E. faecium were comparable to those achieved in sodium selenite diets and lower (p ≤ 0.05) compared to Se-enriched yeast. Concentration of Se in serum and glutathione peroxidase (GSH-Px) activities did not differ in animals fed different Se forms. No differences in indices of meat quality were found among the groups. Se-enriched E. faecium bacteria can be recommended as an alternative selenium source for finisher pigs with the similar efficacy as sodium selenite.
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Kieliszek, Marek, Adam Waśko, Katarzyna Michalak, Anna M. Kot, Kamil Piwowarek, and Stanisław Winiarczyk. "Effect of selenium and methods of protein extraction on the proteomic profile of Saccharomyces yeast." Open Life Sciences 17, no. 1 (January 1, 2022): 1117–28. http://dx.doi.org/10.1515/biol-2022-0496.

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Abstract Selenium may influence the biosynthesis of individual proteins in the yeast cell cytosol. In this study, we used two-dimensional (2D) electrophoresis to identify proteins that are differentially expressed by the enrichment of selenium in Saccharomyces cerevisiae yeast cells. We chose eight protein fractions for further proteomic analysis. A detailed analysis was performed using the Ultraflextreme matrix-assisted laser desorption/ionisation time-of-flight/time-of-flight mass spectrometer, which enables fast and accurate measurement of the molecular weight of the analysed proteins. This study, for the first time, provides evidence that selenium-enriched yeast contains higher levels of mitochondria malate dehydrogenase, adenosine-5′-triphosphate (ATP)-dependent RNA helicase dbp3, and tryptophan dimethylallyltransferase, and alanyl-tRNA editing protein AlaX than yeast without the addition of selenium. It should be emphasised that the proteomic variability obtained reflects the high biological and complexity of yeast metabolism under control and selenium-enriched conditions and can be properly used in the future as a model for further research aimed at determining the expression of appropriate metabolic genes.
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Dissertations / Theses on the topic "Selenium-Enriched yeast"

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Ferhane, Akila. "A novel method for the production of a selenium-enriched yeast /." Thesis, McGill University, 2001. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=37890.

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Selenium (Se) is an essential element. Supplementation of Se as yeast-Se in animal and human diets has been proven to have beneficial health effects. The goal of this study was to add a maximum amount of Se in yeast metabolism in order to optimize its incorporation in amino acids. A bakery yeast strain of Saccharomyces cerevisiae (S. cerevisiae) was studied for its tolerance to Se when the latter was incorporated at different levels. Fermentations were run at 27°C for 8 h and 24 h. The maximum Se incorporation was achieved when 12.6 mmol of Se, as sodium selenite salt, was added to the culture medium and fermented for 24 h. A final Se concentration of 1550 +/- 35 mug/g yeast was obtained by this treatment.
Different yeast strains of S. cerevisiae were also studied for their capacity to incorporate Se. Five yeast strains of wine and four yeast strains of beer were fermented for 24 h and tested for their capacity to incorporate Se. The amount of 12.6 mmol Se was added in the growth medium. A maximum of 642.6 +/- 3.6 mug Se/g yeast was found to be incorporated in Uvaferm BC wine strain. Uvaferm windsor of beer strain was able to incorporate a maximum of 826.8 +/- 10.4 mug Se/g yeast. These yeast strains could be used as alternatives for Se supplementation.
Se speciation was carried out on the bakery yeast strain containing 1550 +/- 35 mug Se/g yeast, using Fast Phase Liquid Chromatography (FPLC) and amino acid analysis. Out of 1550 +/- 35 mug Se/g yeast, 57.5% Se was present as selenoaminoacids. The yeast extract contained 147 +/- 14 mug/g of SeCys, 248 +/- 13 mug/g of SeCyst and 295 +/- 17 mug/g of SeMet. Yeast cell walls contained 65 +/- 8 mug/g of SeMet; 69 +/- 5 mug/g of SeCyst and 67 +/- 9 mug/g of SeCys. These selenoaminoacids are known for their beneficial health effects. The produced Se-enriched bakery yeast could be used, after evaluated to be toxicologically safe, as an efficient dietary supplement.
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Noel, Adrien. "Ιdentificatiοn d'ingrédients alimentaires d'intérêt dans un mοdèle de malnutritiοn assοcié à une entérοpathie." Electronic Thesis or Diss., Normandie, 2024. http://www.theses.fr/2024NORMR018.

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La dénutrition infantile est un enjeu de santé publique majeur et est impliquée dans près de la moitié des décès des enfants de moins de 5 ans. Cette dénutrition est souvent associée à une entéropathie environnementale. Celle-ci se caractérise par une atrophie villositaire, une hyperperméabilité et une inflammation intestinale. À ce jour, aucune solution ne permet de traiter l’entéropathie environnementale.L’objectif de ce travail de thèse était de tester l’efficacité de fibres associées à des levures séléniées sur les paramètres de croissance et la fonction de barrière intestinale dans un modèle murin de dénutrition associé à une entéropathie (UE). Nous avons initialement testé les effets de la gomme arabique combinée aux levures séléniées (GA-SeY) puis nous avons étudié la spécificité de cette supplémentation en comparaison d’autres fibres comme les fibres d’avoine (OAT-SeY), le psyllium (PSY-SeY) et les fructo-oligosaccharides (FOS-SeY) en combinaison avec les levures séléniées.Dans la première étude, le modèle UE présente une diminution du gain de poids et de la croissance, ainsi que des altérations de la fonction de barrière, notamment une hyperperméabilité intestinale et une inflammation intestinale. Une supplémentation d’une semaine en GA-SeY diminue l’inflammation intestinale alors qu’une supplémentation en GA-SeY de deux semaines augmente le gain de poids et permet de diminuer l’hyperperméabilité intestinale et l’inflammation intestinale. Dans la deuxième étude, la supplémentation en GA-SeY de 2 semaines améliore uniquement l’inflammation intestinale alors que celles en OAT-SeY et FOS-SeY n’ont pas d’effet sur les paramètres étudiés. La supplémentation en PSY-SeY exacerbe la perte de poids corporel et diminue la résistance trans-épithéliale jéjunale dans le modèle UE. L’effet bénéfique de deux semaines de supplémentation en GA-SeY sur la fonction de barrière intestinale dans le modèle UE ne se retrouve pas dans les supplémentations associant SeY et fibres d’avoine ou FOS. De plus, la supplémentation psyllium et SeY exerce des effets délétères à la fois sur les paramètres nutritionnels et la fonction de barrière intestinale. Le modèle UE nous a donc permis d’identifier des effets contrastés des supplémentations nutritionnelles sur la croissance des souris et la fonction de barrière en fonction du type de fibres utilisées
Childhood undernutrition is a major public health issue and is involved in 45% of child death under the age of 5. Comorbidities are associated to childhood undernutrition, such as environmental enteropathy, characterized by villous blunting, intestinal permeability, and gut inflammation. Nowadays, no treatment is available to cure environmental enteropathy.The aim of this project was to assess efficacity of fiber associated to selenied yeast, to improve nutritional parameters and gut function in an undernutrition-associated enteropathy (UE) murine model. We began by assess effect of gum arabic and selenied yeast (GA-SeY) on UE model. Then, we compared GA-SeY effect with other fibers combined with SeY: psyllium (PSY-SeY), Oat-fiber (OAT-SeY) and fructo-oligosaccharides (FOS-SeY). First, the UE model induced a lower weight gain and an altered growth, as well as a gut barrier dysfunction, including intestinal hyperpermeability and inflammation. A one-week supplementation of GA-SeY reduces intestinal inflammation while a two-week supplementation of GA-SeY increases weight gain and decreases intestinal hyperpermeability and inflammation. In the second study, 2-week GA-SeY supplementation only improved intestinal inflammation, while OAT-SeY and FOS-SeY supplementation had no effect on the studied parameters. PSY-SeY supplementation exacerbates body weight loss and decreases jejunal trans-epithelial resistance in mice with UE.The beneficial effect of two weeks of GA-SeY supplementation on intestinal barrier function in mice with UE is not reproduced in supplements combining SeY with oat fiber or FOS. Furthermore, psyllium and SeY supplementation exert deleterious effects on both nutritional parameters and intestinal barrier function. The UE model enables to identify contrasting effects of nutritional supplementation on mouse growth and barrier function depending on the type of fiber used
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Martiniano, Sabrina Evelin. "Produção de leveduras enriquecidas com selênio a partir de resíduos vegetais." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/97/97132/tde-20112017-131053/.

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O selênio é um não metal da família 6A e um micronutriente essencial para a saúde animal e humana, com importante ação antioxidante, atuando na prevenção de diversas doenças. O consumo de biomassa de levedura enriquecida com selênio aumenta sua absorção pelo organismo e reduz o risco dos efeitos tóxicos causados pelo consumo de sua forma inorgânica, selenito de sódio. A produção de leveduras enriquecidas com selênio a partir de resíduos amiláceos e lignocelulósicos como fontes de carbono e de nitrogênio é uma alternativa de baixo custo e inovadora. Neste contexto, o presente trabalho teve como objetivo a produção de biomassa de levedura enriquecida com selênio para alimentação animal a partir de resíduos da agroindústria. Foram avaliadas sete linhagens, pertencentes às espécies Candida utilis, Kluyveromyces marxianus, Rhodotorula glutinis e Saccharomyces cerevisiae. Realizaram-se estudos em cultivo submerso com selenito de sódio para avaliar os efeitos no metabolismo microbiano, com ênfase no crescimento celular e incorporação de selênio. Todas as linhagens avaliadas foram capazes de crescer e incorporar selênio, sendo que S. cerevisiae SSS41 apresentou elevada tolerância a esse composto e capacidade de crescimento em hidrolisados amiláceos, acrescidos de selênio. Entre os hidrolisados utilizados no processo fermentativo, o hidrolisado de farelo de soja apresentou elevada concentração de proteínas, não sendo necessária sua suplementação com nutrientes para que a linhagem S. cerevisiae SSS41 produzisse 7,0 g/L de biomassa celular e incorporasse 2375 ppm de selênio. Com a adição de nutrientes e de concentrações mais elevadas de selênio o crescimento celular se manteve constante, porém a incorporação de selênio foi superior a 11000 ppm. Em cultivos realizados com melaço de cana-de-açúcar o crescimento celular foi de 4,17 ± 0,24 g/L, com incorporação de 6528 ± 10 ppm de selênio. Além dos cultivos submersos, também foi realizada fermentação em estado sólido com a levedura R. glutinis CCT-2186, utilizando bagaço de cana-de-açúcar e farelo de arroz hidrolisado como substratos sólidos e hidrolisado de farelo de arroz com e sem a adição de selênio na solução umedecedora. Nos ensaios realizados, a levedura foi capaz de crescer e incorporar 6038 ± 1219 ppm de selênio. O consumo de biomassa de levedura enriquecida com selênio apresenta diversos benefícios à saúde e a utilização de resíduos agroindustriais vegetal é um processo inovador e reduz os custos de produção.
Selenium is an essential micronutrient for animal and human health, with na important antioxidant role, preventing several diseases. Consumption of Se-enriched yeast biomass increases selenium absorption in the digestion process and it is less toxic than its inorganic salt, sodium selenite. The production of Se-enriched yeasts from lignocellulosic and starchy residues as carbon and nitrogen sources is na inexpensive and novel alternative. In this context, the present study aims to produce Se-enriched yeast biomass for animal feed from agroindustrial wastes. Seven yeast strains were evaluated from species Candida utilis, Kluyveromyces marxianus, Rhodotorula glutinis and Saccharomyces cerevisiae. Studies were carried out in submerged culture containing sodium selenite, to verify the effects on microbial metabolism, with emphasis on cell growth and selenium incorporation. All strains evaluated were able to grow and incorporate selenium and S. cerevisiae SSS41 presented high tolerance to this compound and growth capacity in starch hydrolysates containing selenium. Among the hydrolysates used in the fermentation process, soybean bran presented a high protein concentration, and no nutriente supplementation was necessary for the production of 7.0 g/L cellular biomass and incorporation of 2375 ppm of selenium by S. cerevisiae SSS41 strain. With the addition of nutrients and higher concentrations of selenium, cell growth remained steady, but the incorporation of selenium was higher than 11000 ppm. In fermentations carried out with sugarcane molasses, the cell growth of S. cerevisiae SSS41 was 4.17 ± 0.24 g/L, incorporating 6528 ± 10 ppm of selenium. In parallel, solid-state fermentation was carried out with yeast R. glutinis CCT-2186, using sugarcane bagasse and hydrolyzed rice bran as solid substrates and rice bran hydrolyzate with and without the addition of selenium in humidifying solution. In these conditions, the yeast was able to grow and incorporate 6038 ± 1219 ppm of selenium. The consumption of selenium-enriched yeast biomass has several health benefits and the use of agro-industrial wastes is an innovative process and reduces production costs.
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Book chapters on the topic "Selenium-Enriched yeast"

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Nève, J., S. Chamart, S. Van Erum, F. Vertongen, and M. Dramaix. "SELENIUM STATUS IN HUMANS AS INVESTIGATED BY THE EFFECTS OF SUPPLEMENTATION WITH Se-ENRICHED YEAST TABLETS." In Selenium in Medicine and Biology, edited by Jean Nève and Alain Favier, 315–20. Berlin, Boston: De Gruyter, 1988. http://dx.doi.org/10.1515/9783110861990-054.

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Van Erum, S., P. Capel, F. Vertongen, and J. Nève. "EFFECTS OF SELENIUM SUPPLEMENTATION WITH Se ENRICHED YEAST TABLETS ON HEPATIC, MUSCULAR, RENAL AND HEMATOLOGICAL PARAMETERS IN HUMANS." In Selenium in Medicine and Biology, edited by Jean Nève and Alain Favier, 321–24. Berlin, Boston: De Gruyter, 1988. http://dx.doi.org/10.1515/9783110861990-055.

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Zhou, Qiankun, Shoubiao Zhou, and Linxi Yuan. "Ethanol extraction of selenoproteins in selenium-enriched yeast in winemaking." In Selenium in the Environment and Human Health, 151–52. CRC Press, 2013. http://dx.doi.org/10.1201/b15960-68.

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Wuyi, Wang, and Yang Linsheng. "Mitigation of Endemic Arsenocosis with Selenium: An Example from China." In Geology and Health. Oxford University Press, 2003. http://dx.doi.org/10.1093/oso/9780195162042.003.0013.

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Endemic arsenocosis (chronic arsenic poisoning) in China comes from two sources of arsenic (As). One source is drinking water, with As concentrations 2-40 times that of the state standard of 0.05 mg/l As. The second is smoke pollution from combustion of coal with high concentrations of As; this can be inhaled or ingested from smoke-contaminated food. Over 2,000,000 people live in areas of high geological As concentrations (Cao 1996), and more than 17,000 arsenocosis patients in 21 counties of five provinces or Autonomous Regions have been identified. Long-term exposure to As in air, diet, or drinking water can result in permanent and severe damage to health, including lesions of the skin, mucous membranes of the digestive, respiratory, circulatory, and nervous systems, and rhagades (skin cleft on palm and feet). Elevated As intake is also associated with skin, liver, and lung cancers (Centeno 2000, Liang 1999, Wang Lianfang 54-61 1997). At present, there are few studies of efficient measurement of treatment of endemic arsenocosis patients. Our study demonstrates that treatment of these patients with dietary selenium (Se) can cause both excretion (elimination) of As accumulated in the human body and remediation of some health damages. We report the results of this experiment. Data were collected on 3 test groups of people: 186 patients, from BaYinMaoDao Farm in Inner Mongolia suffering from endemic arsenocosis, were divided into a treatment group (100 patients) and a control group (86 patients). A third group, consisting of 70 families, received no treatment but drank ambient well water, >0.10 mg/l As. All participants had been exposed to high-As drinking water (>0.10 mg/l) since 1983. Throughout the experiment, water containing 0.05 mg/1 As was supplied for both treatment and control groups. Of the 186 patients, 100 were treated with Se-enriched yeast tablets, containing 100 μg Se/tablet. The treatment lasted 14 months. Treated patients received 100-200 μg Se/day. All patients were examined for clinical criteria of arsenocosis: characteristic pigmentation, depigmentation, hyperkeratosis, rhagades (skin cleft), and incidence of secondary symptoms of headaches, dizziness, thoracalgia (chest pain), numbness of hands or feet, convulsions, or lumbago.
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Conference papers on the topic "Selenium-Enriched yeast"

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Sun, N. X., Y. H. Liu, and Y. X. Wang. "Utilization of spent brewer's yeast for selenium-enriched yeast." In The 2015 International Conference on Sustainable Development (ICSD2015). WORLD SCIENTIFIC, 2016. http://dx.doi.org/10.1142/9789814749916_0082.

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Kaag, Matt G., John P. Richie, Arun Das, Ana Calcagnotto, Raghu Sinha, Wanda Neidig, Jiangang Liao, et al. "Abstract 3244: Supplementation with selenium-enriched yeast but not selenomethionine reduces oxidative stress in healthy men in a randomized clinical trial." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-3244.

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Sapunova, Leanida, I. Moroz, A. Pauliuk, A. Romashko, and A. Senko. "New selenium-enriched fodder yeasts and their application in rations of laying hens." In 5th International Scientific Conference on Microbial Biotechnology. Institute of Microbiology and Biotechnology, Republic of Moldova, 2022. http://dx.doi.org/10.52757/imb22.30.

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