Academic literature on the topic 'Selection pressures'

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Journal articles on the topic "Selection pressures"

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Campbell, Robert L. "Selection pressures are mounting." Metascience 9, no. 2 (July 2000): 246–53. http://dx.doi.org/10.1007/bf02913608.

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Raven, John A. "Selection pressures on stomatal evolution." New Phytologist 153, no. 3 (March 2002): 371–86. http://dx.doi.org/10.1046/j.0028-646x.2001.00334.x.

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Salek Ardestani, Siavash, Mehdi Aminafshar, Mohammad Bagher Zandi Baghche Maryam, Mohammad Hossein Banabazi, Mehdi Sargolzaei, and Younes Miar. "Whole-Genome Signatures of Selection in Sport Horses Revealed Selection Footprints Related to Musculoskeletal System Development Processes." Animals 10, no. 1 (December 26, 2019): 53. http://dx.doi.org/10.3390/ani10010053.

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Selective breeding has led to gradual changes at the genome level of horses. Deciphering selective pressure patterns is progressive to understand how breeding strategies have shaped the sport horse genome; although, little is known about the genomic regions under selective pressures in sport horse breeds. The major goal of this study was to shed light on genomic regions and biological pathways under selective pressures in sport horses. In this study, whole-genome sequences of 16 modern sport and 35 non-sport horses were used to investigate the genomic selective signals of sport performance, by employing fixation index, nucleotide diversity, and Tajima’s D approaches. A total number of 49 shared genes were identified using these approaches. The functional enrichment analysis for candidate genes revealed novel significant biological processes related to musculoskeletal system development, such as limb development and morphogenesis, having been targeted by selection in sport breeds.
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Corus, Dogan, Andrei Lissovoi, Pietro S. Oliveto, and Carsten Witt. "On Steady-State Evolutionary Algorithms and Selective Pressure: Why Inverse Rank-Based Allocation of Reproductive Trials Is Best." ACM Transactions on Evolutionary Learning and Optimization 1, no. 1 (April 27, 2021): 1–38. http://dx.doi.org/10.1145/3427474.

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We analyse the impact of the selective pressure for the global optimisation capabilities of steady-state evolutionary algorithms (EAs). For the standard bimodal benchmark function TwoMax , we rigorously prove that using uniform parent selection leads to exponential runtimes with high probability to locate both optima for the standard ( +1) EA and ( +1) RLS with any polynomial population sizes. However, we prove that selecting the worst individual as parent leads to efficient global optimisation with overwhelming probability for reasonable population sizes. Since always selecting the worst individual may have detrimental effects for escaping from local optima, we consider the performance of stochastic parent selection operators with low selective pressure for a function class called TruncatedTwoMax, where one slope is shorter than the other. An experimental analysis shows that the EAs equipped with inverse tournament selection, where the loser is selected for reproduction and small tournament sizes, globally optimise TwoMax efficiently and effectively escape from local optima of TruncatedTwoMax with high probability. Thus, they identify both optima efficiently while uniform (or stronger) selection fails in theory and in practice. We then show the power of inverse selection on function classes from the literature where populations are essential by providing rigorous proofs or experimental evidence that it outperforms uniform selection equipped with or without a restart strategy. We conclude the article by confirming our theoretical insights with an empirical analysis of the different selective pressures on standard benchmarks of the classical MaxSat and multidimensional knapsack problems.
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Schneider, Kristan A., and Yuseob Kim. "Genetic Hitchhiking under Heterogeneous Spatial Selection Pressures." PLoS ONE 8, no. 4 (April 24, 2013): e61742. http://dx.doi.org/10.1371/journal.pone.0061742.

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Plotkin, Joshua B., Jonathan Dushoff, Michael M. Desai, and Hunter B. Fraser. "Estimating Selection Pressures from Limited Comparative Data." Molecular Biology and Evolution 23, no. 8 (June 5, 2006): 1457–59. http://dx.doi.org/10.1093/molbev/msl021.

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Dukes, Charles, Sharon M. Darling, and Kim Doan. "Selection Pressures on Special Education Teacher Preparation." Teacher Education and Special Education: The Journal of the Teacher Education Division of the Council for Exceptional Children 37, no. 1 (December 19, 2013): 9–20. http://dx.doi.org/10.1177/0888406413513273.

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Nowick, Katja, Maria Beatriz Walter Costa, Christian Höner zu Siederdissen, and Peter F. Stadler. "Selection Pressures on RNA Sequences and Structures." Evolutionary Bioinformatics 15 (January 2019): 117693431987191. http://dx.doi.org/10.1177/1176934319871919.

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With the discovery of increasingly more functional noncoding RNAs (ncRNAs), it becomes eminent to more strongly consider them as important players during species evolution. Although tests for negative selection of ncRNAs already exist since the beginning of this century, the SSS-test is the first one for also investigating positive selection. When analyzing selection in ncRNAs, it should be taken into account that selection pressures can independently act on sequence and structure. We applied the SSS-test to explore the evolution of ncRNAs in primates and identified more than 100 long noncoding RNAs (lncRNAs) that might evolve under positive selection in humans. With this test, it is now possible to more thoroughly include ncRNAs into evolutionary studies.
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Reynolds, Austin W., Jaime Mata-Míguez, Aida Miró-Herrans, Marcus Briggs-Cloud, Ana Sylestine, Francisco Barajas-Olmos, Humberto Garcia-Ortiz, et al. "Comparing signals of natural selection between three Indigenous North American populations." Proceedings of the National Academy of Sciences 116, no. 19 (April 15, 2019): 9312–17. http://dx.doi.org/10.1073/pnas.1819467116.

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While many studies have highlighted human adaptations to diverse environments worldwide, genomic studies of natural selection in Indigenous populations in the Americas have been absent from this literature until very recently. Since humans first entered the Americas some 20,000 years ago, they have settled in many new environments across the continent. This diversity of environments has placed variable selective pressures on the populations living in each region, but the effects of these pressures have not been extensively studied to date. To help fill this gap, we collected genome-wide data from three Indigenous North American populations from different geographic regions of the continent (Alaska, southeastern United States, and central Mexico). We identified signals of natural selection in each population and compared signals across populations to explore the differences in selective pressures among the three regions sampled. We find evidence of adaptation to cold and high-latitude environments in Alaska, while in the southeastern United States and central Mexico, pathogenic environments seem to have created important selective pressures. This study lays the foundation for additional functional and phenotypic work on possible adaptations to varied environments during the history of population diversification in the Americas.
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Vicens, Alberto, and David Posada. "Selective Pressures on Human Cancer Genes along the Evolution of Mammals." Genes 9, no. 12 (November 28, 2018): 582. http://dx.doi.org/10.3390/genes9120582.

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Cancer is a disease driven by both somatic mutations that increase survival and proliferation of cell lineages and the evolution of genes associated with cancer risk in populations. Several genes associated with cancer in humans, hereafter cancer genes, show evidence of germline positive selection among species. Taking advantage of a large collection of mammalian genomes, we systematically looked for signatures of germline positive selection in 430 cancer genes available in COSMIC. We identified 40 cancer genes with a robust signal of positive selection in mammals. We found evidence for fewer selective constraints—higher number of non-synonymous substitutions per non-synonymous site to the number of synonymous substitutions per synonymous site (dN/dS)—and higher incidence of positive selection—more positively selected sites—in cancer genes bearing germline and recessive mutations that predispose to cancer. This finding suggests a potential association between relaxed selection, positive selection, and risk of hereditary cancer. On the other hand, we did not find significant differences in terms of tissue or gene type. Human cancer genes under germline positive selection in mammals are significantly enriched in the processes of DNA repair, with high presence of Fanconi anaemia/Breast Cancer A (FA/BRCA) pathway components and T cell proliferation genes. We also show that the inferred positively selected sites in the two genes with the strongest signal of positive selection, i.e., BRCA2 and PTPRC, are in regions of functional relevance, which could be relevant to cancer susceptibility.
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Dissertations / Theses on the topic "Selection pressures"

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Nilsson, Annika. "Bacterial adaptation to novel selection pressures /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-192-X/.

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Seemiller, Eric S. "Selective pressures influencing color-vision in Neotropical primates." Kent State University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=kent1309883439.

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Ball, Colleen. "Understanding pathogen selection pressures at the within- and between-host levels." Thesis, University of British Columbia, 2006. http://hdl.handle.net/2429/57.

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Many infectious pathogens, and in particular viruses, have an extremely high rate of mutation. This can lead to rapid evolution driven by selection pressures operating at both the within- and between-host levels, as strains compete for resources within their chosen host while also competing to effectively transmit to new hosts. In the case of chronic viral infections, such as the human immunodeficiency virus (HIV) or hepatitis C, substantial viral evolution may take place within a single infected host. The fitness of a pathogen has been studied at the between-host level and at the within-host level, but linking the two levels of selection pressure is a difficult problem that has yet to be studied satisfactorily. We modify a simple model describing the within host dynamics of HIV infection by including multiple pathogen strains with different properties and allowing these strains to mutate. Within the host we observe different strategies for pathogen success during different stages of infection, which often leads to different strains predominating within the host over the course of infection. We then embed our within-host model into a Monte Carlo simulation that models the interactions between infected individuals. This approach allows us to combine selective pressure at the within-host level with pressures at the between-host level and helps us to predict which strains are most likely to be present within the population. We show that under our model assumptions the co-existence of multiple strains is possible and we explore the factors leading to the success of a pathogen.
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Hoggarth, E. A. "Strategies and pressures in the selection process for community service orders." Thesis, Birmingham City University, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.305740.

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Hatchett, William. "The road toward sympatric speciation in whitefish. : The effects of divergent selection on European whitefish (Coregonus lavaretus) size and behavior, and effects on zooplankton communities." Thesis, Umeå universitet, Institutionen för ekologi, miljö och geovetenskap, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-110741.

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For almost every organism there are large gaps in our knowledge about the processes that leads to speciation. The changes an organism undergoes before divergence has occurred have remained a mystery, as it is difficult to say whether or not a species is going to diverge and when. To investigate this unknown the European whitefish (Coregonus lavaretus) and the northern pike (Esox lucius) were studied, as they produce a repeatable and predictable pattern of speciation in sympatry. To investigate the changes in phenotypes and behaviour in whitefish that precedes divergence, two lake populations were examined, Gräsvattnet and Ringsjön. Gräsvattnet was used as a control, with a population of whitefish but an absence of pike, whereas Ringsjön has a population of whitefish that invaded from Gräsvattnet and a pike population. The presence of pike presumably exerts divergent selection on the whitefish population. Fish and zooplankton were surveyed in both lakes from 1970 to the present day, which allows us to compare how whitefish populations and their resources change in the presence and absence of pike. The results found in Ringsjön show; (1) a change in habitat use, (2) a change in diet from pelagic to benthic, (3) an increase in the relationship between individual body size and diet and (4) a decrease in average size over the course of the study. (1)The presence of pike is believed to have forced the whitefish into the pelagic which could be seen in the result, with an increase in individuals caught in the pelagic. (2) The change in diet is thought to be caused by a resource competition created by individuals being forced to use the pelagic. Although insignificant this led to an overall reduction in zooplankton abundance by almost 40% which could have intensified competition. The resource competition could then have been intensified further by the change in composition of zooplankton relative abundance. (3) The increase in relationship between individual body size and diet is thought to increase due to the resource competition between smaller and larger individuals in the pelagic. Smaller individuals are better competitors than larger individuals for pelagic resource which could have led to the larger individuals switching to a more benthic diet. (4) The decrease in average size is thought to be caused by negative selection for larger individuals. Larger individuals have switched to a more benthic diet, and although the individuals are larger they still face the risk of predation in the littoral zone as they have not outgrown the gape size of the pike. This could have led to the average size reduction that may be the first steps in speciation, and ultimately leading to the divergence of two morphs by sympatric speciation in Ringsjön. In Gräsvattnet over the course of the study there were few and small changes in whitefish size, zooplankton relative abundance in the diet and in the environment. The results in Gräsvattnet could however suggest resource competition for benthic resources. Although resource competition is thought to be an important factor in the speciation of whitefish, without predation pressure no speciation occurs. This result could suggest the importance of predation pressure in the speciation of whitefish.
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Rowe, Candida L. "Multicomponent signals." Thesis, University of Oxford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.299417.

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Pugach, Pavel. "The evolutionary response of the HIV-1 ENV complex to selection pressures in vitro /." Access full-text from WCMC:, 2007. http://proquest.umi.com/pqdweb?did=1428842531&sid=4&Fmt=2&clientId=8424&RQT=309&VName=PQD.

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Siopis, Matthew James. "Wear at high sliding speeds and high contact pressures." Diss., Georgia Institute of Technology, 2015. http://hdl.handle.net/1853/54854.

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Metal on metal wear at high sliding speeds and high contact pressures results in the melting of one or both of the sliding solid bodies due to heat generated at the contact interface. Understanding the influence of sliding speeds, contact pressures and material properties on wear rates is important in developing predictive models for designing more efficient and effective engineering system components. Typical engineering applications subjected to these extreme conditions include ultrahigh speed machining, rocket sleds, large caliber cannon, and electromagnetic launchers. Sliding speeds on the order of 1,000 m/s and contact pressures in excess of 100 MPa are common in these applications and difficult to replicate in a laboratory environment. A unique wedge experiment using a minor caliber electromagnetic launcher has been developed and implemented to characterize wear deposition of a 6061-T6 aluminum sliding body on several different guider materials of varying mechanical and thermal properties at sliding speeds from 0 – 1,200 m/s and contact pressures from 100 – 225 MPa. Optical microscopy and 3D profilometry were used to characterize and quantify the slider wear. Three distinct wear regions, plasticity dominated, severe plastic deformation and melt lubrication were observed. Test results provided evidence that the aluminum slider contact interface was molten. Modeling of the experimental wear data showed a dependence on pressure and velocity and guider material properties, density and specific heat. A predictive wear model was developed for the melt lubrication region as a tool for designing components subjected to similar operating conditions.
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Garcia, Tiffany Sacra. "INTERACTING COLOR AND BEHAVIOR RESPONSES TO MULTIPLE SELECTION PRESSURES IN THE SISTER SALAMANDER SPECIES AMBYSTOMA BARBOURI AND AMBYSTOMA TEXANUM." UKnowledge, 2002. http://uknowledge.uky.edu/gradschool_diss/260.

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My research explores the complex strategies animals adapt to cope with multiple selection pressures. I studied the behavioral and color response of two salamander sister species, Ambystoma barbouri and A. texanum, to temperature, predation risk and ultraviolet radiation (UVR, 280-320 nm). Ambystoma barbouri undergo development in streams, while A. texanum larvae inhabit ponds. Thus, A. barbouri are exposed to increased habitat ephemerality, enhanced predation risk, and UVR exposure. I show how A. barbouri have evolved alternate coping mechanisms in response to these environmental factors, relative to A. texanum. In this comparison study, I've quantified the affects of these selection pressures on larval color change, refuge use and depth choice.I found Ambystoma barbouri to have a significantly darker mean color than A. texanum. Additionally, both species significantly change color to match their background and in response to temperature. When exposed to warm temperatures, early-stage larvae of both species became lighter. Both species also changed color over ontogeny, with larvae becoming significantly lighter over development. Remarkably, A. texanum larvae mediated risk from predatory fish chemical cues by visually assessing the degree to which they cryptically match their background. If cryptic, A. texanum larvae remained on that background color rather than in refuge. A. barbouri larvae preferred to hide in refuge or on dark backgrounds regardless of crypticity, butquickly change color to match their new background. I found that both species darken in response to UVR. When given the choice of refuge, both species spent significantly more time in hiding when UVR was present. When given a choice of water depth, larvae preferred deep water in the presence of UVR radiation.Adapting multiple color and behavioral responses to individual selection pressures help organisms mediate conflicting demands from multiple selection pressures. For example, when predatory fish are present, larvae should move to shallow water to avoid predation. In the presence of UVR, however, larvae should prefer deeper water. I found A. barbouri larvae choose deep water to avoid high UVR exposure despite the risk of predation. Evolving multiple behavioral strategies allows A. barbouri larvae to avoid UVR damage and mediate predation risk.
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Frénoy, Antoine. "Second order selection pressures promoting the evolution and maintenance of cooperation in microbial and in silico systems." Thesis, Paris 5, 2014. http://www.theses.fr/2014PA05T050/document.

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Cette thèse s'intéresse aux liens entre l'évolution de la coopération et la sélection de second ordre. Dans une première partie, nous montrons comment des organismes digitaux adaptent leurs génomes pour encoder les gènes liées à la coopération d'une manière plus contrainte (suppression d'évolvabilité), notamment à l'aide d'opérons et d'overlaps impliquant aussi des gènes essentiels. Dans une deuxième partie, nous testons expérimentalement cette vision des overlaps de gènes comme "contrainte évolutive" grâce à des outils d'algorithmique et de biologie synthétique que nous avons développés. Dans une troisième partie, nous utilisons des simulations par agents pour montrer comment une forme de division du travail peut être interprétée comme un système coopératif à la lumière de la théorie évolutive moderne. Dans une dernière partie, nous montrons que la dispersion spatiale des allèles coopératives obtenue par des phénomènes de "genetic hitchiking" joue un rôle important dans l'évolution de la coopération, quand bien même ce mécanisme de dispersion s'applique aussi à des allèles non coopératives, grâce à la "relatedness" (aux loci codant pour la coopération) crée par l'invasion locale de mutations bénéfiques (à des loci non liés à la coopération) et par l'équilibre complexe entre ces mutations bénéfiques et la robustesse mutationnelle. L'ensemble de ces résultats appelle à une prise en compte plus importante des pressions sélectives de second ordre dans l'étude de l'évolution sociale, et au développement de modèles plus réalistes qui permettraient d'intégrer de telles forces évolutives. Nous insistons également sur l'importance du paysage mutationnel dans l'étude des populations bactériennes, et montrons le potentiel croissant de la biologie synthétique comme outil d'étude de ce paysage et de l'évolution microbienne en général
In the first part, I show how digital organisms adapt their genomes to encode cooperation-related genes in a more constrained way (evolvability suppression), especially using operons and overlaps also involving essential genes. In the second part, we experimentally test this view of gene overlaps as an evolutionary constraint, using both algorithmic and synthetic biology tools that we have developed. In the third part, I use agent-based simulations to show how a form of division of labour can be interpreted as a cooperative system in the light of modern evolutionary theory. In the final part, I show that the patterns of dispersal of cooperative alleles due to hitchhiking phenomena play an important role in the evolution of cooperation. The last result holds even though the hitchhiking mechanisms also applies to non-cooperative alleles, thanks to the relatedness (at cooperation-related loci) created by the local invasion of beneficial mutations (at loci not related to cooperation). The beneficial mutations form a complex and interesting equilibrium with mutational robustness, which I investigate using in silico evolution. On the whole, these results call for a more careful consideration of the second-order selection pressures in the study of social evolution, and show the necessity for more realistic models allowing to integrate such evolutionary forces. My thesis research specifically highlights the importance of the mutational landscape in the study of microbial populations and shows the increasing potential of synthetic biology as a tool to study such landscape and microbial evolution in general
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Books on the topic "Selection pressures"

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Hoggarth, Elizabeth Anne. Strategies and pressures in the selection process for Community Service Orders. Birmingham: City of Birmingham Polytechnic, 1987.

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Hoggarth, Elizabeth Anne. Strategies and pressures in the selection process for community service orders. Birmingham: Birmingham Polytechnic, 1987.

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Hoggarth, Elizabeth Anne. Strategies and pressures in the selection process for community service orders. Birmingham: Birmingham Polytechnic, 1987.

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Pressure sensors: Selection and application. New York: M. Dekker, 1991.

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Zappe, R. W. Valve selection handbook: Engineering fundamentals for selecting manual valves, check valves, pressure relief valves, and rupture discs. 4th ed. Houston, Tex: Gulf Pub. Co., 1999.

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Agency, United States Federal Emergency Management. Tornado protection: Selecting refuge areas in buildings. 2nd ed. Washington, D.C: FEMA, 2009.

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Spiller, Pablo T. Buy, lobby or sue: Interest groups' participation in policy-making : a selective survey. Cambridge, Mass: National Bureau of Economic Research, 2006.

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A, Campbell William. Outgassing data for selecting spacecraft materials. Washington, D.C: National Aeronautics and Space Administration, Scientific and Technical Information Office, 1987.

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A, Campbell William. Outgassing data for selecting spacecraft materials. Washington, D.C: National Aeronautics and Space Administration, Office of Management, Scientific and Technical Information Branch, 1993.

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A, Campbell William. Outgassing data for selecting spacecraft materials. Washington, D.C: National Aeronautics and Space Administration, Office of Management, Scientific and Technical Information Division, 1990.

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Book chapters on the topic "Selection pressures"

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Rosano, Matt. "Selection Pressures." In Encyclopedia of Sciences and Religions, 2121. Dordrecht: Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-1-4020-8265-8_200103.

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Apostolou, Menelaos. "The Weak Negative Selection Pressures Hypothesis." In The Evolution of Same-Sex Attraction, 111–25. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-53925-2_8.

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Koenig, Bryan L. "Selection Pressures as a Function of Age." In Encyclopedia of Evolutionary Psychological Science, 1–4. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-16999-6_3016-1.

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Koenig, Bryan L. "Selection Pressures as a Function of Age." In Encyclopedia of Evolutionary Psychological Science, 6904–7. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-319-19650-3_3016.

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Pawłowski, Bogusław, and Wioletta Nowaczewska. "Origins of Homininae and Putative Selection Pressures Putative selection pressures Acting on the Early Hominins Early hominines." In Handbook of Paleoanthropology, 1887–918. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-39979-4_46.

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Turner, Jonathan H. "Selection Pressures and the Evolution of the Macrodynamic Realm." In Theoretical Principles of Sociology, Volume 1, 21–39. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-6228-7_2.

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Apostolou, Menelaos. "Weak Negative Selection Pressures on Same-Sex Attraction Across Time." In The Evolution of Same-Sex Attraction, 159–76. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-53925-2_11.

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Pawłowski, Bogusław, and Wioletta Nowaczewska. "Origins of Hominini and Putative Selection Pressures Acting on the Early Hominins." In Handbook of Paleoanthropology, 1–29. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-27800-6_46-6.

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Orgeig, S., and C. B. Daniels. "Environmental Selection Pressures Shaping the Pulmonary Surfactant System of Adult and Developing Lungs." In Cardio-Respiratory Control in Vertebrates, 205–39. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-93985-6_10.

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Pawłowski, Bogusław. "3 Origins of Homininae and Putative Selection Pressures Acting on the Early Hominins." In Handbook of Paleoanthropology, 1409–40. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-33761-4_46.

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Conference papers on the topic "Selection pressures"

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Lindstrom, Leena. "Anthropogenic selection pressures and the consequences of sublethal pesticide usage." In 2016 International Congress of Entomology. Entomological Society of America, 2016. http://dx.doi.org/10.1603/ice.2016.93938.

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Ollion, Charles, Tony Pinville, and Stéphane Doncieux. "With a little help from selection pressures: evolution of memory in robot controllers." In International Conference on the Simulation and Synthesis of Living Systems. MIT Press, 2012. http://dx.doi.org/10.7551/978-0-262-31050-5-ch054.

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Rollins, Alex C., and Jacob Schrum. "Balancing selection pressures, multiple objectives, and neural modularity to coevolve cooperative agent behavior." In GECCO '17: Genetic and Evolutionary Computation Conference. New York, NY, USA: ACM, 2017. http://dx.doi.org/10.1145/3067695.3075979.

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Graham, Nicholas, Aspram Minasyan, Heather Christofk, Ingo Mellinghoff, and Thomas G. Graeber. "Abstract A113: Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures." In Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics; October 26-30, 2017; Philadelphia, PA. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1535-7163.targ-17-a113.

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Graham, Nicholas A., Aspram Minasyan, Heather R. Christofk, Ingo K. Mellinghoff, and Thomas G. Graeber. "Abstract 2672: Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-2672.

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Weaver, Kenneth D. "A Critical Look at Use of ``Rules of Thumb'' for Selection of Grout Injection Pressures." In Geo-Denver 2000. Reston, VA: American Society of Civil Engineers, 2000. http://dx.doi.org/10.1061/40516(292)12.

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Dogan, B. "Hydrogen Storage Tank Systems and Materials Selection for Transport Applications." In ASME 2006 Pressure Vessels and Piping/ICPVT-11 Conference. ASMEDC, 2006. http://dx.doi.org/10.1115/pvp2006-icpvt-11-93868.

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The present international socio-economic drive for renewable energy use for sustainable development with environmental protection directs attention to hydrogen as energy carrier. Hydrogen production and storage, and fuel cell (FC) technologies have been intensively worked on in Europe including European Commission (EC) supported projects via Framework Programs (FPs), as well as various national and international cooperative programs including those of International Energy Agency (IEA) and International Partnership for Hydrogen Economy (IPHE). The hydrogen storage is required for transport applications as dense as possible to achieve high gravimetric and volumetric density. The storage of hydrogen in liquid, gas and solid forms are associated with low temperature cooling, higher pressures up to 700 bar and integrated higher volume and weight, respectively. The liquid and pressurized gas storage systems are relatively advanced in present applications. On the other hand, the system safety and reliability, hence the public acceptance as well as economic feasibility have been the main drives for solid and hybrid hydrogen applications. The use of solid hydrogen is predicted by the automotive industry to ultimately dominate the hydrogen transport application market. The bottleneck in solid hydrogen application is metal hydride production to meet the quantitative targets for vehicles mainly following the US DOE goals set for years up to 2015. System requirements need also be met for a present target of e.g. 75kWel fuel cell cars aiming at a 400km driving distance with 4 kg of hydrogen. This necessitates a gravimetric storage density of over 6 wt. per cent. The present paper will address the hydrogen storage tank system for on-board applications including storage tank materials, system design, production technologies and system safety. An overview will be presented on the current state-of-the-art of European and international progress on storage materials integrated into on-board storage tank system. The European current programs on hydrogen storage technologies for transport applications including design, safety and system reliability will be addressed.
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Pal, S., C. Iek, L. J. Peltier, A. Smirnov, K. J. Knight, D. Zheng, and J. Jarvis. "Verification and Validation of CFD Model to Predict Jet Loads and Blast Wave Pressures From High Pressure Superheated Steam Line Break." In ASME 2016 Power Conference collocated with the ASME 2016 10th International Conference on Energy Sustainability and the ASME 2016 14th International Conference on Fuel Cell Science, Engineering and Technology. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/power2016-59675.

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High pressure superheated or saturated steam line breaks in a nuclear power plant generate high speed jet flows and blast waves. The jet loads and blast wave pressures can damage critical nuclear power plant components. An accurate assessment of these effects including uncertainty quantification (UQ), is essential to confirm that design is robust enough to handle jet flows and blast waves from postulated steam line breaks. This paper presents the verification and validation of a computational model created using a commercial CFD code for making such assessments. The verification and validation process involves the steps of application space parametrization, Phenomena Identification and Ranking (PIR), CFD model lockdown, selection of validation dataset, and calculation of formal validation metrics. The Uncertainty Quantification in the actual application should include the propagated validation uncertainties from the validation test problems.
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MuniReddy, Muthukuru G., and Subramanian Neelamani. "Reduction of Wave Pressures on Vertical Seawall/Caissons Due to an Offshore Breakwater." In ASME 2003 22nd International Conference on Offshore Mechanics and Arctic Engineering. ASMEDC, 2003. http://dx.doi.org/10.1115/omae2003-37074.

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Estimation of wave pressures on vertical impermeable caissons and seawall is needed to determine the dimensions and appropriate material selection of the structure. Reduction of extreme wave loadings (pressures) by constructing an offshore breakwater on seaward side of these structures is investigated. A series of physical model tests were carried out in a wave flume to examine the performance of the defense structure (offshore breakwater) in reducing the wave pressures on the seawall/caisson. Quasi-static nature of the wave pressures was observed due to piling-up of fluid mass behind the breakwater. The influence of the pool length on reduction of pressures on seawall/caisson is also investigated for regular waves.
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Joseph, Thomas. "Recommended List of “Known” Materials for Hydrogen Service." In ASME 2005 Pressure Vessels and Piping Conference. ASMEDC, 2005. http://dx.doi.org/10.1115/pvp2005-71155.

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The paper will address commonly used materials in Hydrogen service and their limitations as the service conditions (like pressure) get into more challenging areas. For example, Aluminum has good history of use in hydrogen applications upto 3000 psig. It’s compatible with Hydrogen even at pressures higher than 15,000 psig. However, are we comfortable in continued use of Aluminum and similar low melting point materials at higher pressures for containing Hydrogen? The paper is expected to provide basis for a discussion on this safety issue. In addition, the paper will include a discussion around pressure vs stress level limits for common materials. A user friendly material selection chart will be presented for the benefit of the audience.
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Reports on the topic "Selection pressures"

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Lebow, Stan, Juliet Tang, Grant T. Kirker, and Mark Mankowski. Guidelines for the selection and use of pressure-treated wood. Madison, WI: U.S. Department of Agriculture, Forest Service, Forest Products Laboratory, 2019. http://dx.doi.org/10.2737/fpl-gtr-275.

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Klepper, C. Christopher. Species Selective Pressure Gauge for High Performance Divertors. Office of Scientific and Technical Information (OSTI), April 2002. http://dx.doi.org/10.2172/1337330.

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Natesan, K., S. Majumdar, P. S. Shankar, and V. N. Shah. Preliminary materials selection issues for the next generation nuclear plant reactor pressure vessel. Office of Scientific and Technical Information (OSTI), March 2007. http://dx.doi.org/10.2172/925328.

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Klepper, C. Christopher. Species Selective Pressure Gauge for High Performance Divertors. Final report. Office of Scientific and Technical Information (OSTI), June 1999. http://dx.doi.org/10.2172/761553.

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ELLINGSON, S. D. 236-Z and 291-Z Vacuum Pump System Pressure Drop Analysis for Line Size Selection. Office of Scientific and Technical Information (OSTI), May 2000. http://dx.doi.org/10.2172/803649.

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Hazelton, W. S. Technical report on material selection and processing guidelines for BWR coolant pressure boundary piping. Draft report. Revision 2. Office of Scientific and Technical Information (OSTI), June 1986. http://dx.doi.org/10.2172/5708682.

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Rich Ciora and Paul KT Liu. Hydrogen Selective Inorganic membranes for Gas Separations under High Pressure Intermediate Temperature Hydrocarbonic Envrionment. Office of Scientific and Technical Information (OSTI), June 2012. http://dx.doi.org/10.2172/1044183.

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Whyatt, G. A., L. D. Anderson, and J. II Evans. Detailed design data package: 3.1a-Film cooler pressure drop data; Item 3.2a - SBS packing selection; Item 3.2b, 3.2c - Pressure drop data for SBS distribution plate; and Item 3.2e - SBS distribution plate and liquid risers. PHTD pilot-scale melter testing system cost account milesonte 1.2.2.04.15A. Office of Scientific and Technical Information (OSTI), March 1996. http://dx.doi.org/10.2172/212722.

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