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1

Suikkanen, Jussi. "The Possibility of Love Independent Reasons." Essays in Philosophy 12, no. 1 (2011): 32–54. http://dx.doi.org/10.5840/eip201112116.

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In his recent work, Harry Frankfurt has defended a theory according to which an agent’s practical reasons are determined by what she happens to love. In the first section of this article, I will describe some of the awkward consequences of this view. For instance, it would turn out that not all rapists would have reasons not to rape their victims. The second section of the article explains in detail Frankfurt’s argument for his theory of reasons. The crux of this argument is that, because reasons have to be attached to significant life-changes, any attempt to show that there were love independent reasons would need to be based on a prior evaluation of significance. However, such evaluations can only be based on what we already love, or so Frankfurt argues. From this threat of circularity, Frankfurt concludes that there cannot be reasons outside the realm of the objects of our loves. The rest of the article is a critical examination of Frankfurt’s argument. It first constructs an analogical argument for reasons for beliefs. In that case, both the unacceptable consequences of the argument and its basic flaws are more transparent. It is clear that our prior beliefs are not the only epistemic standard by which the justificatory role of new experiences is to be evaluated. In the end of the article, I argue that, likewise, our prior loving attitudes cannot be the only relevant standard for assessing the significance of life-changes. This is why our reasons are not constrained by what we love.
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2

Tombs, David. "Jon Sobrino and ‘the Crucified People’." Religions 14, no. 2 (February 17, 2023): 274. http://dx.doi.org/10.3390/rel14020274.

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‘The crucified people’ became a key theological concern in the writings of Jon Sobrino SJ in the 1990s. This article examines how and why Sobrino made this concern a central element in his theology at the time. Section 2 discusses what Sobrino has described as his ‘awakening from the sleep of inhumanity’ in the 1970s as he encountered liberation theology in El Salvador following his doctoral studies in Frankfurt. Section 3 examines three figures in the Salvadoran Church who influenced Sobrino: Ignacio Ellacuría (assassinated 1989); Oscar Romero (assassinated 1980); and Rutilio Grande (assassinated 1977). All three paid with their lives for their work in the Church. Section 4 examines the understanding of the crucified people offered by Ellacuría in 1978, and the encouragement for this idea in the words of Romero and Grande in 1977. Sections 5 and 6 turn to the use of the term as used by Sobrino himself. Section 5 argues that Sobrino’s early Christological writings are quite cautious in their use of this idea. The murder of Ellacuría by the military in November 1989 at the Central American University—alongside the killing of five fellow Jesuits, their housekeeper, and her daughter—appears to be the pivotal event that prompts Sobrino’s bolder discussion in publications from 1989 onwards (Section 6).
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Erbacher, Philipp, Brückner Benjamin, Sophia Florence Dellmann, Kathrin Göbel, Tanja Heftrich, Markus Reich, Cem Deniz Kurtulgil, et al. "Direct reactions for nuclear astrophysics." EPJ Web of Conferences 279 (2023): 06005. http://dx.doi.org/10.1051/epjconf/202327906005.

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The neutron activation technique is a well established method to measure neutron capture cross sections relevant for the s-process. The 7Li(p,n) reaction at Ep = 1912 keV is often used as a neutron source since the energy distribution of the emitted neutrons closely resembles a Maxwell-Boltzmann spectrum of kBT = 25 keV, mimicking the 22Ne(α,n) phase in TP-AGB stars. The weak s-process, which takes place in massive stars, can reach energies up to kBT = 90 keV. Neutron spectra corresponding to a Maxwell-Boltzmann distribution with kBT > 25 keV cannot be produced by the 7Li(p,n) reaction directly. We developed a method to obtain quasi-Maxwellian neutron capture cross sections over a wide energy range by combining a set of spectrum average cross sections measured at six different proton energies and distances between the lithium target and the sample. The measured spectrum averaged cross section can be used to calculate the Maxwellian-Averaged cross-section (MACS) from kBT = 25 keV to kBT = 90 keV. Over the last two years neutron capture cross sections on over 20 isotopes have been measured at Goethe University Frankfurt using this methodology. An overview of the current experimental method, challenges during data analysis and the first results are presented.
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4

Jankowski, Paweł. "Filozofia polityczna Hegla w interpretacji Joachima Rittera." Politeja 17, no. 4(67) (October 15, 2020): 54–72. http://dx.doi.org/10.12797/politeja.17.2020.67.03.

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Hegel’s Political Philosophy in Joachim Ritter’s InterpretationThis article outlines Joachim Ritter’s attempt to detach Hegel’s political and social philosophy from its Marxist interpretation. The first section examines the differences between the reception of Hegel’s legacy by Ritter and by the Frankfurt School. The latter views Hegel primarily as a forerunner of Marx, while Ritter perceives Hegel as committed theorist and advocate of modern state and civil society. The second section focuses on Ritter’s attitude towards the post-revolutionary society. In particular, it explores Ritter’s interpretation of the concept of modern university and interest in history as a reaction to rapid modernization. The last section turns to Ritter’s criticism of the rejection of the contemporary social and political realities – represented by both right-winged reactionaries and far-left progressivists – and also demonstrates Ritter and his School’s contribution to intellectual legitimization of the post-war German Federal Republic.
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5

Ohnesorge, Christopher, Julia Wilkes, Marius Eichfelder, Jinnus Rastegar, Matthias Derra, and Julia Balmer. "The Constitutionality of § 89a of the German Criminal Code (StGB) and the Concept of a Serious Act of Violent Subversion: The German Federal Court of Justice (Bundesgerichtshof), Judgement of 8th May 2014 - 3 StR 243 / 13." German Law Journal 18, no. 3 (May 1, 2017): 631–46. http://dx.doi.org/10.1017/s2071832200022094.

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As a reaction to the increasing terrorist threat in Europe, the German Parliament (Bundestag) passed a law penalizing the preparation of terrorist acts endangering the state: § 89a German Criminal Code (StGB). The Regional Court of Frankfurt am Main (LG Frankfurt) was the first to apply this section to a case where a young man was accused of building a pipe bomb. Upon his conviction, the defendant appealed to the German Federal Court of Justice (BGH), claiming § 89a StGB to be unconstitutional. The BGH reviewed whether the statute was in conformity with the principles of the German Constitution (GG), including the principle of legal certainty and appropriateness. It held that these principles were fulfilled, if stricter requirements are applied regarding the mens rea in order to counterbalance the broad actus reus. It decided that the Regional Court had not fulfilled this particular requirement and quashed the conviction insofar. This case and § 89a StGB caused ripples amongst legal scholars, especially due to the unusual penalization of preparatory acts and the broad scope of the statute's application. This case also produced an unprecedented change within the judge's bench.
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6

Briciu, Adrian. "Bullshit, trust, and evidence." Intercultural Pragmatics 18, no. 5 (October 21, 2021): 633–56. http://dx.doi.org/10.1515/ip-2021-5003.

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Abstract It has become almost a cliché to say that we live in a post-truth world; that people of all trades speak with an indifference to truth. Speaking with an indifference to how things really are is famously regarded by Harry Frankfurt as the essence of bullshit. This paper aims to contribute to the philosophical and theoretical pragmatics discussion of bullshit. The aim of the paper is to offer a new theoretical analysis of what bullshit is, one that is more encompassing than Frankfurt’s original characterization. I part ways with Frankfurt in two points. Firstly, I propose that we should not analyze bullshit in intentional terms (i.e. as indifference). Secondly, I propose that we should not analyze it in relation to truth. Roughly put, I propose that bullshit is best characterized as speaking with carelessness toward the evidence for one’s conversational contribution. I bring forward, in the third section, a battery of examples that motivate this characterization. Furthermore, I argue that we can analyze speaking with carelessness toward the evidence in Gricean terms as a violation of the second Quality maxim. I argue that the Quality supermaxim, together with its subordinate maxims, demand that the speaker is truthful (contributes only what she believes to be true) and reliable (has adequate evidence for her contribution). The bullshitter’s main fault lies in being an unreliable interlocutor. I further argue that we should interpret what counts as adequate evidence, as stipulated by the second Quality Maxim, in contextualist terms: the subject matter and implicit epistemic standards determine how much evidence one needs in order to have adequate evidence. I contrast this proposed reading with a subjectivist interpretation of what counts as having adequate evidence and show that they give different predictions. Finally, working with a classic distinction, I argue that we should not understand bullshit as a form of deception but rather as a form of misleading speech.
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7

Sullivan, Daniel. "Review of Jeremiah Morelock (Ed.), Critical Theory and Authoritarian Populism (2018). London: University of Westminster Press." tripleC: Communication, Capitalism & Critique. Open Access Journal for a Global Sustainable Information Society 17, no. 1 (April 29, 2019): 101–10. http://dx.doi.org/10.31269/triplec.v17i1.1090.

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Critical Theory and Authoritarian Populism (2018; University of Westminster Press), edited by Jeremiah Morelock, brings together the work of sociologists, political scientists, historians, and philosophers attempting to revitalise the empirical and theoretical work on antidemocratic trends of the early Frankfurt School, or Institute for Social Research. They do so in the analytic context of contemporary, globally observed ‘authoritarian populist’ movements, in which political (often right-wing) agitators pit a symbolically-constructed national ‘people’ against purported corrupt elites and minority scapegoat groups. The chapters cover wide ground and can be contrasted to some extent in terms of whether they frame the contemporary moment as highly similar to the era of the Great Depression and 1930s Fascism, or emphasise the unique nature of neoliberalism as a historical backdrop. Notable strengths of the volume include Morelock’s systematic introductory overview of early Frankfurt School work, as well as a thematic section on “Digital Authoritarianism” which resurrects the Institute’s tradition of propaganda content analysis for the social media era. Critical Theory and Authoritarian Populism offers a highly comprehensive picture of the current geopolitical nightmare and the conceptual tools for attacking it, and serves as a welcome corrective to several recent simplistic applications of the authoritarianism concept in popular science outlets.
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Güngör, Emre Sinan, Duygu Güzel, Ali Galip Zebitay, Gülşah İlhan, and Fatma Ferda Verit. "The efficacy of onion extract in the management of subsequent abdominal hypertrophic scar formation." Journal of Wound Care 29, no. 10 (October 2, 2020): 612–16. http://dx.doi.org/10.12968/jowc.2020.29.10.612.

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Objective: Development of postoperative scars is often a problem. This study aimed to evaluate the efficacy of gel containing Allium cepa extract, allantoin and heparin (Contractubex, Merz Pharmaceuticals GmbH, Frankfurt, Germany) in reducing scarring after a caesarean section by comparing it with a control group, and also intra-individually, using the Vancouver Scar Scale (VSS). Method: A total of 120 patients who underwent a second elective caesarean delivery and who presented with hypertrophic scar development after their first caesarean section were included in the study. A scar revision was performed for all patients during the second caesarean operation. Patients in the study group (n=60) were advised to apply the topical scar gel postoperatively for a period of 6 months. The control group (n=60) received no treatment. Results: Significant reductions were observed in the vascularity, pigmentation and height subgroups of the VSS for those in the group who continued the treatment to 24 weeks. An intra-individual analysis showed that the gel effectively reduced scarring after the second caesarean section. Conclusion: The prophylactic use of the gel to reduce scar development offers better results for vascularity, pigmentation and height subscales of the VSS after surgical removal of the primary caesarean scar during the second caesarean section. The results were better both intra-individually, and also in comparison with the control group and support the use of a gel containing Allium cepa extract, allantoin and heparin to reduce scarring after a caesarean section.
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9

Welz, Claudia, Essi Ikonen, and Aslaug Kristiansen. "Learning through Listening and Responding: Probing the Potential and Limits of Dialogue in Local and Online Environments." Religions 14, no. 2 (February 10, 2023): 241. http://dx.doi.org/10.3390/rel14020241.

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This article explores an age-old form of dialogical learning, havruta, which has been employed by Jews throughout the centuries to study the Torah and the Talmud, and evaluates the experiment of extending havruta from a couple of fellow students (haverim) to an international, multi-religious group reading philosophical texts together, and transferring the learning process from the Jewish house of study (in Hebrew: beit ha-Midrash, in German: Lehrhaus) to an online environment. Methodologically, the experiences from the online havruta are brought into a theory-practice feedback loop and are discussed from various theoretical angles: (1) The first section introduces how havruta was conducted traditionally and how Franz Rosenzweig, who in 1920 founded the Frankfurt Lehrhaus and invited Martin Buber to offer lecture courses, advanced havruta. (2) The second section explains how Rosenzweig’s pedagogical principles as distilled from his writings on education are applied and modified in the above-mentioned contemporary online reading group. (3) The third section draws on Buber’s philosophy of dialogue, Juhani Pallasmaa’s architectural theory and Michel Chion’s film theory in order to investigate the epistemological and pedagogical significance of different modes of listening, asking, and responding, and the role of trust for dialogical learning in local and online learning communities.
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10

Ertl, Thomas. "Money Topples Borders." Medieval History Journal 16, no. 2 (October 2013): 501–24. http://dx.doi.org/10.1177/0971945813515020.

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In the late Middle Ages and in the early modern period, the European continent was characterised by a vast mobility of skilled and unskilled labour: Italian merchants established themselves in Bruges and in other commercial centres, German soldiers and craftsmen intermittently lived in Italy, merchants from many different nations met at trade fairs which regularly took place in Frankfurt am Main and in other cities and countless journeymen went on the road before they established themselves as master craftsmen somewhere. This migration was accompanied by an exchange of commodities, technologies and ideas across all political borders. One may think that these different exchange processes would have led to an economic convergence on the European continent. Why this was not, or was only to a certain extent the case, will be discussed in the second section of this essay.
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Niesen, Peter. "Reframing civil disobedience: Constituent power as a language of transnational protest." Journal of International Political Theory 15, no. 1 (November 9, 2018): 31–48. http://dx.doi.org/10.1177/1755088218808001.

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In 1992, the Frankfurt scholar Ingeborg Maus launched a polemical attack against then current narratives of democratic protest, objecting to the languages of ‘resistance’ or ‘civil disobedience’ as defensive, servile and insufficiently transformative. This article explores in how far the language of constituent power can be adopted as an alternative justificatory strategy for civil disobedience in transnational protests. In contrast to current approaches that look at states as agents of international civil disobedience-as-constituent power, I suggest we look at political movements. I focus on the example of the Democracy in Europe Movement 2025 (DiEM25) which understands itself as a pan-European movement of civil disobedience, at the same time working towards an articulation and exercise of constituent power among the people(s) of Europe. In the final section, I sharpen the criteria for the invocation of constituent power in transnational protest in distinguishing between its articulation, activation and exercise.
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12

Angulo, Cecilia Coronado. "Instrumental Reason, Technology, and Society." Dialogue and Universalism 33, no. 1 (2023): 59–76. http://dx.doi.org/10.5840/du20233314.

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Technological development is accompanied by a paradox: while it often promises enormous benefits for humanity, it can also lead to inconceivable tragedy, including the instrumentalization of the individual, growing social inequality, environmental impact, etc. What causes this paradox? a) Could it be that the nature of technology generates this contradiction? b) Is it the agent that uses it? c) Or is it the circumstances in which technology is used that determine its suitability or disservice? My aim in this paper is to revise nature, causes and political explanations of the paradox. To do so, the first section will give a historical overview of this phenomenon, the second will assess three proposals that attempt to explain its origin, and, finally, the paper will weigh such approaches from the view of the Frankfurt School. Evaluating the paradoxical conditions that surround technology allows us to better understand its role in our societies.
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13

Stompfe, Philipp. "The Higher Regional Court of Frankfurt am Main Is the First European Court to Declare the Achmea Case a Landmark Decision with Significance for All Intra-EU BITS." European Investment Law and Arbitration Review Online 6, no. 1 (December 20, 2021): 270–81. http://dx.doi.org/10.1163/24689017_0601013.

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In February 2021, the Higher Regional Court of Frankfurt am Main (Oberlandesgericht – “olg”), rendered a decision in the case between the Republic of Croatia (“Croatia”) as the applicant, and an Austrian bank incorporated as a joint stock company under Austrian law and a Croatian bank incorporated as a joint stock company under the laws of Croatia having the Austrian bank as its sole shareholder as the Respondents (“Respondents”). This decision concerns the incompatibility of an arbitration clause contained in the Agreement between the Republic of Austria and Croatia on the Promotion and Protection of Investments (“Austria-Croatia bit”)2 with EU law. Croatia successfully challenged the admissibility of an uncitral arbitration based on Article 9(2)(b) of the Austria- Croatia bit, initiated by the Respondents, by virtue of an application under Section 1032(2) of the German Code of Civil Procedure (Zivilprozessordnung – “zpo”). Croatia argued that Article 9(2)(b) of the Austria- Croatia bit was incompatible with EU law.
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Stompfe, Philipp. "The Higher Regional Court of Frankfurt am Main Is the First European Court to Declare the Achmea Case a Landmark Decision with Significance for All intra-EU BITs." European Investment Law and Arbitration Review 6, Issue 1 (January 1, 2021): 270–81. http://dx.doi.org/10.54648/eila2021013.

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In February 2021, the Higher Regional Court of Frankfurt am Main (Oberlandesgericht– ‘OLG’), rendered a decision in the case between the Republic of Croatia (‘Croatia’) as the applicant, and an Austrian bank incorporated as a joint stock company under Austrian law and a Croatian bank incorporated as a joint stock company under the laws of Croatia having the Austrian bank as its sole shareholder as the Respondents (‘Respondents’). This decision concerns the incompatibility of an arbitration clause contained in the Agreement between the Republic of Austria and Croatia on the Promotion and Protection of Investments (‘Austria-Croatia BIT’) with EU law. Croatia successfully challenged the admissibility of an UNCITRAL arbitration based on Article 9(2)(b) of the Austria-Croatia BIT, initiated by the Respondents, by virtue of an application under Section 1032(2) of the German Code of Civil Procedure (Zivilprozessordnung – ‘ZPO’). Croatia argued that Article 9(2)(b) of the Austria-Croatia BIT was incompatible with EU law.
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Kastamoni, Yadigar, Ahmet Dursun, Veysel Atilla Ayyıldız, and Kenan Öztürk. "Numerical variations and localization of foramen spinosum in 3D-CT images." Anatomy 15, no. 1 (April 1, 2021): 59–63. http://dx.doi.org/10.2399/ana.21.899266.

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Objectives: The structures passing through the foramen spinosum and its neurovascular relationships are of great importance for surgical approches directed to middle cranial fossa. The aim of the present study was to examine the number and location of the foramen spinosum (FS) in 3D-CT images. Methods: The study was retrospectively conducted on 3D-CT images of 177 adults. Firstly, the transverse section passing through the upper edge of the orbit, extending parallel to the Frankfurt plane was chosen. Then, the x and y-axes were determined on that transverse section. The coordinates, number, and location of the FS with respect to the foramen ovale (FO) were identified accordingly on x and y-axes. Results: While 1 FS was present in 90.96% of a total of 354 sides of 177 heads, there were 2 FS and 3 FS in 8.76% and 0.28% of the sides, respectively. The FS was located posterolaterally in 97.68%, posteriorly in 2.06%, and laterally in 0.26% with respect to the FO. In terms of FS coordinates, there was no statistically significant difference between gender and sides in the distance of the FS to the x-axis, but there was a statistically significant difference between gender and sides in the distance of the FS to the y-axis. Conclusion: Evaluation of the number of the FS and its location would help identifying and preserving neighbouring neurovascular structures during surgical interventions directed to the middle cranial fossa.
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Abdullah, Johari Yap, Cicero Moraes, Mokhtar Saidin, Zainul Ahmad Rajion, Helmi Hadi, Shaiful Shahidan, and Jafri Malin Abdullah. "Forensic Facial Approximation of 5000-Year-Old Female Skull from Shell Midden in Guar Kepah, Malaysia." Applied Sciences 12, no. 15 (August 5, 2022): 7871. http://dx.doi.org/10.3390/app12157871.

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Forensic facial approximation was applied to a 5000-year-old female skull from a shell midden in Guar Kepah, Malaysia. The skull was scanned using a computed tomography (CT) scanner in the Radiology Department of the Hospital Universiti Sains Malaysia using a Light Speed Plus scanner with a 1 mm section thickness in spiral mode and a 512 × 512 matrix. The resulting images were stored in Digital Imaging and Communications in Medicine (DICOM) format. A three-dimensional (3D) model of the skull was obtained from the CT scan data using Blender’s 3D modelling and animation software. After the skull was reconstructed, it was placed on the Frankfurt plane, and soft tissue thickness markers were placed based on 34 Malay CT scan data of the nose and lips. The technique based on facial approximation by data extracted from facial measurements of living individuals showed greater anatomical coherence when combined with anatomical deformation. The facial approximation in this study will pave the way towards understanding face prediction based on skull structures, soft tissue prediction rules, and soft tissue thickness descriptors.
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17

Millican, Peter. "Hume's Determinism." Canadian Journal of Philosophy 40, no. 4 (December 2010): 611–42. http://dx.doi.org/10.1080/00455091.2010.10716737.

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David Hume has traditionally been assumed to be a soft determinist or compatibilist, at least in the ‘reconciling project’ that he presents in Section 8 of the first Enquiry, entitled ‘Of liberty and necessity.’ Indeed, in encyclopedias and textbooks of Philosophy he is standardly taken to be one of the paradigm compatibilists, rivalled in significance only by Hobbes within the tradition passed down through Locke, Mill, Schlick and Ayer to recent writers such as Dennett and Frankfurt. Many Hume scholars also concur in viewing him as a determinist, for example (in date order) Norman Kemp Smith, Barry Stroud, A. J. Ayer, Paul Russell Don Garrett, Terence Penelhum, George Botterill, John Bricke, and John Wright. My main purpose in this paper will be to provide the evidence to substantiate this traditional interpretation, which has hitherto been widely assumed rather than defended. In the absence of such a defence, the consensus has been left open to challenge, most notably in a recent paper and a subsequent book by James Harris, who boldly claims that Hume ‘does not subscribe to determinism of any kind, whether Hobbesian or merely nomological.’
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18

Heger, Martin. "BgHSt 20, 22 und die Neubürger-Klausel des deutschen Strafanwendungsrechts – ein deutsch-polnischer Fall schreibt Rechtsgeschichte bis heute." Miscellanea Historico-Iuridica 19, no. 2 (2020): 141–60. http://dx.doi.org/10.15290/mhi.2020.19.02.08.

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In its judgment of the 4th September 1964 the German Federal Court of Justice had to deal with a German-Polish case of murder. The accused persons were members of the German minority in Poland and lived in the Western part of Poland, when German troops occupied that territory in the autumn of 1939. Short after the invasion they killed the members of a Jewish family living in the same territory. Both, the perpetrators as well as the victims were Polish nationals, when the crime was committed. The perpetrators have got the German nationality in the following. It is not clear, whether they have been naturalized by German authorities during WW II, but if not, they were seen as German nationals with the Getting-into-Force of the German Basic Law (Constitution), because they were refugees from Poland to Germany. Therefore, Article 116 § 1 Basic Law naturalized them as German nationals. For the criminal case it was crucial whether the later naturalization can give the German Justice system jurisdiction over a case which happened before the perpetrator has reached the German nationality, as it was (and still is) stated in section 4 (resp. today section 7) of the German Criminal Code. The paper should deal with the implications of this so-called "New Citizenship Clause" and with the circumstances of the case and the following cases at Western German Courts against German people for committing murder in the occupied Polish territories during WWII. Shortly after the named case, the Auschwitz trial started in Frankfurt. On that background, the paper reflects on the situation between West and East Germany as well.
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19

Schulting, Dennis. "The Functionality of Christian Life: Problems of The Early Hegel's Epistemology of Religion." Hegel Bulletin 27, no. 1-2 (2006): 107–24. http://dx.doi.org/10.1017/s0263523200007564.

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In this paper I want to explore a central line of reasoning in Hegel's early philosophy of religion, which he expounded in fragments he wrote while he was in Bern and Frankfurt in the 1790's. These fragments are known under the titles, Fragmente über Volksreligion und Christentum (dated around 1793–94), Die Positivität der christlichen Religion (1795–96), Entwürfe über Religion und Liebe, and a later essay entitled Der Geist des Christentums und sein Schicksat, they were written sometime between 1798 and 1800, a few years before Hegel published his seminal Jena texts, but they remained unpublished in his lifetime. These texts have, since Nohl's edition of 1907, come to be known collectively as Hegel's ‘theologische Jugendschriften’. I believe that they contain the inchoate system of Hegel's thought in general and his mature philosophy of religion in particular. My main claim here is that Hegel believes that there is an intimate relation between reason and religion, so much so in fact that one can argue that there is reason in religion.In the first section of my paper, I elaborate on some general problems concerning the relation between faith and reason, in particular, concerning the criterion of truth and viewpoint-neutrality. In the second section, I introduce Hegel's well-known problematic of the sublation of conceptual oppositions, which in the context of an account of the positivity of religion he already articulates, in some form, in these early documents and which may provide a solution for the problems that, in the first section, I argue arise around the relation between faith and reason. This will be merely a rough outline. I subsequently discuss, very briefly, some central aspects of Kant's philosophy of religion, to which to an important extent Hegel's is indebted. In the fourth section, I go on to indicate, also very broadly, the sense in which Hegel attempts to improve upon Kant and thus apparently proves to be more consistent than him. I then raise an issue concerning Hegel's particularist position in his epistemology of religion, which does not sit well with the notion of rationality as viewpoint-neutral. To illustrate this, I look at Hegel's reading of the Eucharist. This is all very sketchy and is meant mainly to elucidate the sense in which, according to Hegel, there is reason in religion.
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Barth, W., M. Basten, C. Burandt, T. Conrad, F. Dziuba, V. Gettmann, T. Kürzeder, et al. "Advanced basic layout of the HElmholtz LInear Accelerator for cw heavy ion beams at GSI." Journal of Physics: Conference Series 2687, no. 5 (January 1, 2024): 052009. http://dx.doi.org/10.1088/1742-6596/2687/5/052009.

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Abstract The design and construction of continuous wave (cw) high intensity linacs is a crucial goal of worldwide accelerator technology development. The standalone sc heavy ion linac HELIAC (HElmholtz LInear ACcelerator) is a common project of GSI Helmholtz Centre for Heavy Ion Research and Helmholtz Institute Mainz (HIM) under key support of Goethe University Frankfurt (IAP). In 2017 the first section of the linac has been successfully commissioned and extensively tested with beam at GSI, featuring the capability of 216.816 MHz multi-gap Crossbar H-mode (CH) DTL-structures. At present, the first fully equipped cryomodule of the HELIAC is under construction. In addition, six further superconducting CH cavities are being procured. The HELIAC beam dynamics concept foresees a total of twelve CH-cavities in order to accelerate ions with a mass-to-charge ratio of 6 up to an energy of 7.5 MeV/u. In this paper, an advanced very compact and less complex layout is presented, where the same number of accelerating cavities can be accommodated in three instead of four cryomodules, thus also reducing the number of solenoids and rebunchers. In addition, the integration and linking of the HELIAC to the GSI accelerator UNILAC will be outlined.
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Paul, B., CJ Möllmann, U. Kielland-Kaisen, S. Schulze, W. Schaarschmidt, N. Bock, D. Brüggmann, F. Louwen, and L. Jennewein. "Maternal and neonatal outcome after vaginal breech delivery at term after cesarean section – a prospective cohort study of the Frankfurt breech at term cohort (FRABAT)." European Journal of Obstetrics & Gynecology and Reproductive Biology 252 (September 2020): 594–98. http://dx.doi.org/10.1016/j.ejogrb.2020.04.030.

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22

Nicholls, David. "Richard Cobden and the International Peace Congress Movement, 1848–1853." Journal of British Studies 30, no. 4 (October 1991): 351–76. http://dx.doi.org/10.1086/385989.

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Between 1848 and 1853 a series of major peace congresses was held—in Brussels (1848), Paris (1849), Frankfurt (1850), London (1851), Manchester (1853), and Edinburgh (1853). This midcentury period was one of great confidence and optimism in the likely success of the cause. Indeed, reading the reports of the congresses today, one is struck by the at times naive overoptimism of many delegates. This may in part have been the product of the millenarian atmosphere of the period. However, it has to be said that the congresses were also characterized by a strong sense of the practicality of their proposals and the steady progress toward their goal that implementation of such proposals would achieve. Above all, the efflorescence of the peace movement in the short six years around the midcentury was the product of a class confidence, of a momentary triumphalism that inspired a section of the bourgeoisie to believe that the scourge of war could be eradicated at last.The nineteenth-century peace movement effectively began with the establishment toward the end of the Napoleonic Wars, independently and virtually simultaneously, of peace societies in the United States and Britain. They were dominated by men of religion, particularly Quakers, and for a quarter of a century their work was essentially that of proselytizing the peace cause through publicity, petitions, and lecture tours. In connection with the last, the London Peace Society sent emissaries on tours of continental Europe in the early 1840s to spread the peace message.
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Svedentsov, E. P. "Joint Congress of the International Society for Blood Transfusion (European Section) and the German Society for Transfusion Medicine and Immunohematology (October 1-4, 1997, Frankfurt am Main, Germany)." Kazan medical journal 79, no. 4 (July 15, 1998): 309–11. http://dx.doi.org/10.17816/kazmj64507.

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The Congress was devoted to topical issues of transfusion medicine, among which the standardization of donor blood and its components should be highlighted, the use of PCR analysis for blood testing, auto donation, the creation of blood substitutes - oxygen carriers, the use of cytokines to obtain stem cells of peripheral blood and bone marrow, their cryopreservation and transplantation.
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Hoock, Samira, B. Paul, C. J. Möllmann, J. Wildner, A. Hentrich, W. Schaarschmidt, F. Louwen, and L. Jennewein. "An update on maternal and neonatal outcome after vaginal breech delivery at term after cesarean section – a prospective cohort study of the Frankfurt breech at term cohort (frabat)." European Journal of Obstetrics & Gynecology and Reproductive Biology 293 (February 2024): 112. http://dx.doi.org/10.1016/j.ejogrb.2023.08.315.

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Zielbauer, Ann-Sophie, Frank Louwen, and Lukas Jennewein. "External cephalic version at 38 weeks’ gestation at a specialized German single center." PLOS ONE 16, no. 8 (August 30, 2021): e0252702. http://dx.doi.org/10.1371/journal.pone.0252702.

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Introduction Cesarean section (CS) rates are increasing worldwide. One constant indication is the breech presentation at term. By offering external cephalic version (ECV) and vaginal breech delivery CS rates can be further reduced. Objective This study aimed to analyze the ECV at 38 weeks of gestation with the associate uptake rate, predicting factors, success rate, and complications at a tertiary healthcare provider in Germany specializing in vaginal breech delivery. Methods We conducted a prospective cohort study with retrospective data acquisition. All women with a singleton fetus in breech presentation presenting after 34 weeks of gestation for counseling between 2013 and 2017 were included. ECV impact factors were analyzed using logistic regression. Results A total of 1,598 women presented for breech birth planning. ECV was performed on 353 patients. The overall success rate was 22.4%. A later week of gestation (odds ratio [OR] 1.69), an abundant amniotic fluid index (AFI score) (OR 5.74), fundal (OR 3.78) and anterior (OR 0.39) placental location, and an oblique lie (OR 9.08) were significantly associated with successful ECV in our population. No major complications were observed. The overall vaginal delivery rates could be increased to approximately 14% with ECV. Conclusion The demand for alternative birth modes other than CS for breech birth is high in the area of Frankfurt, Germany. Our study offers evidence of the safety of ECV at 38 weeks. Centers with expertise in vaginal breech delivery and ECV can reduce CS-rates. To further establish vaginal breech delivery and ECV as alternate options, the required knowledge and skill should be implemented in the revised curricula.
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Frey, Katharina, Johann Philipp Zöllner, Susanne Knake, Yulia Oganian, Lara Kay, Katharina Mahr, Fee Keil, et al. "Risk incidence of fractures and injuries: a multicenter video-EEG study of 626 generalized convulsive seizures." Journal of Neurology 267, no. 12 (July 10, 2020): 3632–42. http://dx.doi.org/10.1007/s00415-020-10065-5.

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Abstract Objective To evaluate the incidence and risk factors of generalized convulsive seizure (GCS)-related fractures and injuries during video-EEG monitoring. Methods We analyzed all GCSs in patients undergoing video-EEG-monitoring between 2007 and 2019 at epilepsy centers in Frankfurt and Marburg in relation to injuries, falls and accidents associated with GCSs. Data were gathered using video material, EEG material, and a standardized reporting form. Results A total of 626 GCSs from 411 patients (mean age: 33.6 years; range 3–74 years; 45.0% female) were analyzed. Severe adverse events (SAEs) such as fractures, joint luxation, corneal erosion, and teeth loosening were observed in 13 patients resulting in a risk of 2.1% per GCS (95% CI 1.2–3.4%) and 3.2% per patient (95% CI 1.8–5.2%). Except for a nasal fracture due to a fall onto the face, no SAEs were caused by falls, and all occurred in patients lying in bed without evidence of external trauma. In seven patients, vertebral body compression fractures were confirmed by imaging. This resulted in a risk of 1.1% per GCS (95% CI 0.5–2.2%) and 1.7% per patient (95% CI 0.8–3.3%). These fractures occurred within the tonic phase of a GCS and were accompanied by a characteristic cracking noise. All affected patients reported back pain spontaneously, and an increase in pain on percussion of the affected spine section. Conclusions GCSs are associated with a substantial risk of fractures and shoulder dislocations that are not associated with falls. GCSs accompanied by audible cracking, and resulting in back pain, should prompt clinical and imaging evaluations.
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VALERA, SALVADOR. "Conversion and onomasiological theory." Journal of Linguistics 36, no. 1 (March 2000): 145–55. http://dx.doi.org/10.1017/s0022226799007951.

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Pavol štekauer,A theory of conversion in English. Frankfurt am Main: Peter Lang, 1996. Pp. 155.When, in 1891, Henry Sweet (1891–98, I: 38–40) used the term CONVERSION for the process that today is also known as ZERO-DERIVATION, he was probably not aware of the debate that the description of this process would still raise one century later.štekauer's book bears witness to a renewed interest in conversion. Such an interest partly stems from the fact that it is a simple (or, at least, apparently so), extremely productive process, but also because it remains a challenge to descriptive linguistics. How conversion operates, what its limits are, how converted units should be categorised in the study of morphology and lexis, and even what its real nature is are still open questions despite the attention given to this issue ever since Sweet's grammar.This book meets some of these questions in the framework of an onomasiological theory, which will be briefly discussed below. The book consists of nine chapters, a section for notes and another for references. The introduction (chapter 1, pp. 11–13) justifies the work and outlines the structure of the book. The remaining eight chapters deal with the description of conversion in the literature (chapter 2, pp. 15–22), its interpretation as zero-derivation (chapter 3, pp. 23–43), the onomasiological theory and conversion (chapter 4, pp. 45–53), phonological variation (chapter 5, pp. 55–95), the use and semantic range of converted units (chapter 6, pp. 97–113), proper nouns and conversion (chapter 7, pp. 115–126), directionality (chapter 8, pp. 127–133), and the productivity of conversion (chapter 9, pp. 135–141).
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Allen, John. "Powerful City Networks: More than Connections, Less than Domination and Control." Urban Studies 47, no. 13 (November 2010): 2895–911. http://dx.doi.org/10.1177/0042098010377364.

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Powerful cities are often distinguished from others by the concentration and mix of resources at their disposal. The right mix, the right people and skills, along with the ability to do something with them marks off the more powerful from the less powerful cities. In that respect, far reaching influence and control are the hallmarks of a powerful city. Often implicit in this view, however, is an understanding of power as something which a city possesses, a capacity for domination and control embedded in the city itself which gives it a ranking above others. This paper sets out an alternative way of thinking about how power ‘works’ for cities that is not based upon hierarchical domination or a zero sum game. The first part outlines a view of power as a means to an end, a medium that enables cities to hold networks together and bridge connections. Following that, the ‘power to’ run the networks, to exercise power with rather than over others, is illustrated through the example of the international division of labour that holds between the London and Frankfurt financial centres. In particular, the key role of intermediate elites as brokers is highlighted. This analysis is developed further in the final section by taking the example of Sydney as a powerful ‘switching point’, but one where intermediaries broker and bridge global networks to gain advantage — not through practices of domination and control, but more subtle modes of power such as manipulation and inducement, which operate at the expense of others. In so doing, the ‘power to’ make things happen folds over into power over others.
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Augschöll Blasbichler, Annemarie, and Michaela Vogt. "Between and Beyond. The Course of a Life in the Realms of History of Education, General Pedagogy and Comparative Studies. Interview with Edwin Keiner." Espacio, Tiempo y Educación 7, no. 2 (July 7, 2020): 235–47. http://dx.doi.org/10.14516/ete.380.

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Edwin Keiner held the chair for General Pedagogy and Social Pedagogy at the Free University of Bozen-Bolzano until his retirement in October 2019. From 2014 to 2017 he also served as Vice Dean of the Faculty of Education at the same university. Prior to that, he worked as a professor for the History of Education and Socialisation at the University of Bochum and as a professor for General Pedagogy at the University of Erlangen-Nuremberg. He has studied the theory and the history of education as an academic discipline with special interest in a comparative perspective. His academic focus is on methodology, historical and comparative research on educational research, and historical, empirical and comparative as well as interdisciplinary approaches to and in educational research. For several years he took over the role as chairman of the Commission for Research on Educational Research and of the Section for General Pedagogy of the German Educational Research Association. In addition, Keiner was very active in the European Educational Research Association (EERA) for example as the first elected representative of all networks and member of the EERA Council. In 2018, Keiner succeeded in bringing the annual «European Conference on Educational Research» (ECER) with about 3,000 participants to the Free University of Bozen-Bolzano, Italy, South Tyrol. He was a member of the «International Research Community ‘Philosophy and History of The Discipline of Education’» (University Leuven, Belgium) for almost 20 years and member of the editorial boards of Paedagogica Historica, European Educational Research Journal and Educational Assessment, Evaluation and Accountability. At present, Edwin Keiner works part-time as a senior professor at the Faculty of Education, University of Frankfurt/Main, Germany.
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Pui, Ching-Hon, Martin Schrappe, Raul C. Ribeiro, and Charlotte M. Niemeyer. "Childhood and Adolescent Lymphoid and Myeloid Leukemia." Hematology 2004, no. 1 (January 1, 2004): 118–45. http://dx.doi.org/10.1182/asheducation-2004.1.118.

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Abstract Remarkable progress has been made in the past decade in the treatment and in the understanding of the biology of childhood lymphoid and myeloid leukemias. With contemporary improved risk assessment, chemotherapy, hematopoietic stem cell transplantation and supportive care, approximately 80% of children with newly diagnosed acute lymphoblastic leukemia and 50% of those with myeloid neoplasm can be cured to date. Current emphasis is placed not only on increased cure rate but also on improved quality of life. In Section I, Dr. Ching-Hon Pui describes certain clinical and biologic features that still have prognostic and therapeutic relevance in the context of contemporary treatment programs. He emphasizes that treatment failure in some patients is not due to intrinsic drug resistance of leukemic cells but is rather caused by suboptimal drug dosing due to host compliance, pharmacodynamics, and pharmacogenetics. Hence, measurement of minimal residual disease, which accounts for both the genetic (primary and secondary) features of leukemic lymphoblasts and pharmacogenomic variables of the host, is the most reliable prognostic indicator. Finally, he contends that with optimal risk-directed systemic and intrathecal therapy, cranial irradiation may be omitted in all patients, regardless of the presenting features. In Section II, Dr. Martin Schrappe performs detailed analyses of the prognostic impact of presenting age, leukocyte count, sex, immunophenotype, genetic abnormality, early treatment response, and in vitro drug sensitivity/resistance in childhood acute lymphoblastic leukemia, based on the large database of the Berlin-Frankfurt-Münster consortium. He also succinctly summarizes the important treatment components resulting in the improved outcome of children and young adolescents with this disease. He describes the treatment approach that led to the improved outcome of adolescent patients, a finding that may be applied to young adults in the second and third decade of life. Finally, he believes that treatment reduction under well-controlled clinical trials is feasible in a subgroup of patients with excellent early treatment response as evidenced by minimal residual disease measurement during induction and consolidation therapy. In Section III, Dr. Raul Ribeiro describes distinct morphologic and genetic subtypes of acute myeloid leukemia. The finding of essentially identical gene expression profiling by DNA microarray in certain specific genetic subtypes of childhood and adult acute myeloid leukemia suggests a shared leukemogenesis. He then describes the principles of treatment as well as the efficacy and toxicity of various forms of postremission therapy, emphasizing the need of tailoring therapy to both the disease and the age of the patient. Early results suggest that minimal residual disease measurement can also improve the risk assessment in acute myeloid leukemia, and that cranial irradiation can be omitted even in those with central-nervous-system leukemia at diagnosis. In Section IV, Dr. Charlotte Niemeyer describes a new classification of myelodysplastic and myeloproliferative diseases in childhood, which has greatly facilitated the diagnosis of myelodysplastic syndromes and juvenile myelomonocytic leukemia. The recent discovery of somatic mutations in PTPN11 has improved the understanding of the pathobiology and the diagnosis of juvenile myelomonocytic leukemia. Together with the findings of mutations in RAS and NF1 in the other patients, she suggests that pathological activation of RAS-dependent pathways plays a central role in the leukemogenesis of this disease. She then describes the various treatment approaches for both juvenile myelomonocytic leukemia and myelodysplastic syndromes in the US and Europe, emphasizing the differences between childhood and adult cases for the latter group of diseases. She also raises some controversial issues regarding treatment that will require well-controlled international clinical trials to address.
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Heftrich, Tanja, Kafa Al-Khasawleh, Sandra Borzek, Benjamin Brückner, Sophia Florence Dellmann, Ozan Can Dogan, Asmaa El Mard, et al. "Neutron activations for lower s-process temperatures." EPJ Web of Conferences 279 (2023): 06011. http://dx.doi.org/10.1051/epjconf/202327906011.

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The slow neutron capture process produces heavy elements in different stellar sites at different temperatures. Neutron capture cross sections for stellar temperatures between kBT = 5 keV and kBT = 100 keV are crucial for a quantitative understanding of the s-process abundance distribution. Over the last decade activation measurements were performed at the Goethe University Frankfurt to study cross sections at a temperature of kBT = 25 keV. We developed a new method to measure neutron capture cross sections at kBT = 6 keV.
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32

Jenks, Stuart. "Distributionsrevolution des 15. Jahrhunderts." Hansische Geschichtsblätter 132 (July 14, 2020): 47–78. http://dx.doi.org/10.21248/hgbll.2014.102.

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The Distribution Revolution of the Fifteenth CenturyThe consumption revolution of the long eighteenth Century (c. 1650-1850) was inconceivable without a prior distribution revolution in Northwest Europe, in the course of which markets were linked in a stable hierarchy reaching from the international fairs of Antwerp and Frankfurt down to humble packmen tramping from village to village. The exotic products of the consumption revolution did not have to surmount any significant distribution problems, because the networks had been functioning since the fifteenth Century. The proof of this hypothesis is divided into two parts, one empirical and the other theoretical. The foundation of some 2000 weekly markets in England between 1200 and 1350 resulted from the interaction of peasants’ cash requirements and improved transportation by horse: There was much money to be made by establishing markets, but peasants could choose between them. This set in train a brutal winnowing of markets which was intensified in the late middle ages by the effects of the plague, the enclosure movement and price-wage developments. In the end, the surviving markets had organized themselves into a hierarchy based on London, which was, by 1500, indisputably the center of foreign trade and the distribution of imports in England. This section concludes by showing that the hierarchization of markets was also characteristic of the Hanseatic area during the same period. The theoretical part of the paper demonstrates that the hierarchization of markets changed the framework for economic actors in a way no person or group could alter. Late medieval industrial mass production, succeeded by early modern proto-industrialization, required efficient labor markets and distribution networks. Placing the price signals generated by urban markets at the center of the argument solves a number of troubling problems of proto-industrialization: the geographical concentration of proto-industries, the outsourcing of simple tasks (and the retention of more sophisticated processes) and thesubsequent urbanization of rural industrial clusters. It also allows us to go beyond Diamond and Krugman and construct a real-world model of the rise of market hierarchization, as traders exploited scale economies derived from the difference between urban Wholesale and rural retail prices, and - by concentrating their trade on the most liquid provincial markets (thus maximizing thick market externalties) - locked these satellite markets into the hierarchy. An examination o f the policies o f the London Grocers and Mercers proves that this did, indeed, take place in the course of the fifteenth Century. Therefore, the distribution revolution was a true revolution, one which changed forever the framework for economic actors in a way 110 person or group could alter (,economic Constitution‘).
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Kutzner, Maximilian. "Das Wirtschaftsressort der Frankfurter Allgemeinen Zeitung und die Medialisierung der Wirtschaftspolitik in den 1950er Jahren." Vierteljahrschrift für Sozial- und Wirtschaftsgeschichte 101, no. 4 (2014): 488–99. http://dx.doi.org/10.25162/vswg-2014-0018.

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Goulemot, Jean M., Thomas Steinfeld, and Gilles Marcotte. "La place de la littérature dans les médias en notre fin de millénaire1." Études françaises 36, no. 3 (December 16, 2004): 149–60. http://dx.doi.org/10.7202/009728ar.

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Résumé Présentés d’abord dans le cadre d’une table ronde tenue au Goethe Institut en mars 1999, les textes réunis dans cette section portent sur les liens entre la littérature et un espace public en mutation. Trois lecteurs : Gilles Marcotte, critique au Devoir et à L’Actualité, Thomas Steinfeld, directeur de la section littéraire au quotidien allemand Frankfurter Allgemeine Zeitung, et Jean M. Goulemot, critique au Monde, y réfléchissent à l’inscription de la littérature dans la vie culturelle contemporaine, à ses principaux enjeux ainsi qu’aux circonstances de sa diffusion et de sa réception.
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ANISOVICH, V. V., M. N. KOBRINSKY, V. A. NIKONOV, and J. NYÍRI. "1/Nc EXPANSION, QUARK MODEL AND HADRON COLLISIONS AT HIGH ENERGIES." International Journal of Modern Physics A 01, no. 02 (July 1986): 463–80. http://dx.doi.org/10.1142/s0217751x86000198.

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Soft hadron-collision processes at high energies are considered, under the assumption that gluon interactions are short-ranged and that the rules of the 1/Nc expansion are fulfilled. It is shown, that these considerations lead to the scheme of the additive quark model with some relatively large additional effects of colour screening. This colour screening is responsible for the unnatural breaking of the Levin-Frankfurt condition1 and also for the effective increase of cross sections for hadron-nucleus interactions2 if quark bags in nuclei exist, The formation mechanism of fragmentational particles is considered in multiple hadron-production processes.
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Slavkovská, Zuzana, Anton Wallner, René Reifarth, Stefan Pavetich, Lukas Bott, Benjamin Brückner, Kathrin Göbel, et al. "Investigation of 54Fe(n,γ)55Fe and 35Cl(n, γ)36Cl reaction cross sections at keV energies by Accelerator Mass Spectrometry." EPJ Web of Conferences 232 (2020): 02005. http://dx.doi.org/10.1051/epjconf/202023202005.

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Activations with neutrons in the keV energy range were routinely performed at the Karlsruhe Institute of Technology (KIT) in Germany in order to simulate stellar conditions for neutron-capture cross sections. A quasi-Maxwell-Boltzmann neutron spectrum of kT = 25 keV, being of interest for the astrophysical s-process, was produced by the 7Li(p,n) reaction utilizing a 1912 keV proton beam at the Karlsruhe Van de Graaff accelerator. Activated samples resulting in long-lived nuclear reaction products with half-lives in the order of yr 100 Myr were analyzed by Accelerator Mass Spectrometry (AMS). Comparison of the obtained reaction cross sections to literature data from previous Time-of-Flight (ToF) measurements showed that the selected AMS data are systematically lower than the ToF data. To investigate this discrepancy, 54Fe(n,γ)55Fe and 35Cl(n,γ)36Cl reaction cross sections were newly measured at the Frankfurt Neutron Source (FRANZ) in Germany. To complement the existing data, an additional neutron activation of 54Fe and 35Cl at a proton energy of 2 MeV was performed. The results will give implications for the stellar environment at kT = 90 keV, reaching the not yet experimentally explored high-energy s-process range. AMS measurements of the activated samples are scheduled.
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Graf, Christiana, Inken Wagener, Katharina Grikscheit, Sebastian Hoehl, Annemarie Berger, Nils Wetzstein, Julia Dietz, et al. "Is Olfactory Testing a Useful Diagnostic Tool to Identify SARS-CoV-2 Infections Early? A Cross-Sectional and Longitudinal Analysis." Journal of Clinical Medicine 12, no. 9 (April 27, 2023): 3162. http://dx.doi.org/10.3390/jcm12093162.

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BACKGROUND: Genesis and the prognostic value of olfactory dysfunction (OD) in COVID-19 remain partially described. The objective of our study was to characterize OD during SARS-CoV-2 infection and to examine whether testing of OD may be a useful tool in clinical practice in order to early identify patients with SARS-CoV-2 infection. METHODS: Olfactory function assessment was objectively carried out using the u-Smell-it® test. In a cross-sectional study part, we evaluated this test in a control cohort of SARS-CoV-2 negative tested patients, who attended the University Hospital Frankfurt between May 2021 and March 2022. In a second longitudinal study part, sensitivity and specificity of OD was evaluated as a diagnostic marker of a SARS-CoV-2 infection in Frankfurt am Main, Germany in SARS-CoV-2 infected patients and their close contacts. RESULTS: Among 494 SARS-CoV-2 negative tested patients, OD was detected in 45.7% and was found to be significantly associated with the male gender (p < 0.001), higher age (p < 0.001), cardiovascular and pulmonary comorbidities (p < 0.001; p = 0.03). Among 90 COVID-19 positive patients, OD was found in 65.6% and was significantly associated with male gender and positive smoking status (p = 0.04 each). Prevalence and severity of OD were significantly increased in infections with the Delta variant (B.1.617.2) compared to those with the Omicron variant (BA.1.1.529). Diagnostic sensitivity and specificity of OD for diagnosis of SARS-CoV-2 infection were 69% and 64%, respectively. CONCLUSION: OD is common in COVID-19 negative and positive tested patients with significantly different prevalence rates observed between different variants. Diagnostic accuracy of OD is not high enough to implement olfactory testing as a tool in diagnostic routine to early identify patients with a SARS-CoV-2 infection.
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Xiong, Xin, Qinlanhui Zhang, and Yang Liu. "Correlations between mandibular ramus height and occlusal planes in Han Chinese individuals with normal occlusion: A cross-sectional study." APOS Trends in Orthodontics 11 (January 12, 2022): 295–300. http://dx.doi.org/10.25259/apos_78_2021.

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Objectives: The objective of the study is to determine the relationships between ramus height and occlusal planes (OPs) in Han Chinese individuals with normal occlusion. Materials and Methods: Two hundred and four participants with normal occlusion were included and their cephalograms were analyzed. The ramus height (Ar-Go), Frankfort horizontal plane-posterior OP (FH-POP), FH-anterior OP (FH-AOP) and FH-OP, anterior and posterior cranial base length, SNA, SNB, ANB, Frankfort-mandibular plane angle, SN-MP, jaw angle, and mandibular body length were measured on the subjects’ cephalograms. Pearson correlation coefficients were calculated among continuous variables. The ramus height was considered as dependent variable and the OPs as independent variables. Age, sex, and other cephalometric parameters were considered as possible confounding factors. Univariate and multivariate analyses were performed to determine whether the relationships were significant. Results: The FH-POP and FH-OP were moderately associated with ramus height, while the FH-AOP showed a weak association (P < 0.001). After adjusting age and sex, FH-POP, FH-AOP, and FH-OP showed significant negative associations with ramus height (β = −0.36, −0.28, and −0.37, respectively, P < 0.001). The OP flattened with the ramus height increased. After adjusting all the confounding factors, FH-POP and FH-OP showed significant negative associations with ramus height. The ramus height increased by 0.19 mm/1° flattening of FHPOP (β = −0.19, P = 0.002). Conclusion: After adjust age, sex, and other possible confounding factors, the FH-POP and FH-OP were associated with the ramus height. The flattening of FH-POP was associated with the increase of ramus height. The results should be treated with caution since it’s a cross-sectional study.
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Thomsen, Lene Frølund. "Livsoplysning og livsfilosofiske perspektiver - et uddannelsesmæssigt modsvar til tidens fokus på kompetenceudvikling." Grundtvig-Studier 53, no. 1 (January 1, 2002): 252–62. http://dx.doi.org/10.7146/grs.v53i1.16431.

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Fra livsoplysning og livsfilosofiske perspektiver- et uddannelsesmæssigt modsvar til tidens fokus på kompetenceudvikling[From ‘Life-enlightenment' and ‘life-philosophical’ perspectives – a pedagogic challenge to the contemporary focus on ‘competence-development ’]By Lene FrølundViewed in the context of education, competence-development [kompetenceudvikling] is the sign of the times. Within current educational research, the concept of ‘competence’ seems to have been identified as post modernity’s answer to the question of how individuals can learn to bring and keep themselves abreast of development in a complex knowledge- and informationbased society which imposes requirements of control, skillful steering and readiness to adapt.The pedagogic theme which sets the agenda in this debate on post-modern educational ideals is emancipation-pedagogy [frigørelsespædagogik], which has its roots in the Frankfurt School and Critical Theory, and which reaches back to the ideals of Liberty and Reason in the Age of Enlightenment. Since the nineteen-seventies emancipation-pedagogy has almost exclusively set the pedagogic agenda in Denmark. With its background in a philosophy based upon scientific rationalism, it has made its essential objective the development of the pupil’s critical sense. Thus political education and, subsumed in this, the development of a democratic disposition [det demokratiske sindelag] have been prioritised, at the cost of a strengthening of the philosophical disposition [det filosofiske sindelag] - as in the discussion of the perennial questions of existence.It is this rational-scientific outlook upon education with which Regner Birkelund takes issue in his book, Livs-Oplysning [Life-enlightenment]. With a background in N. F. S. Grundtvig and K. E. Løgstrup his aim is to enquire how one may combine a vocation-orientated education with a humane educational orientation. The enquiry is centred about a concrete example within nursing - a pedagogic experiment which took place at Testrup Højskole between 1927 and 1975. This folk-highschool featured a course preliminary to the school of nursing where future nurses were to be taught general highschool subjects together with specialised nursing subjects. The ideal was a learning process which was motivated by enjoyment and free participation and thus where not only reason but also the heart was involved.From Testrup, Birkelund traces the thread back to Gr. and aims thus to demonstrate that it was Gr’s pedagogic ideas - and herein Gr’s concept of lifeenlightenment (livsoplysning)- which formed the basis of the experiment in Testrup. Birkelund hereby offers an excellent introduction to Gr’s educational ideas.With the historical-poetic as his point of departure, Birkelund leads us in the final section of the book from Gr. to Løgstrup, for he believes that Løgstrup’s ethical and aesthetic views - and herein his concept of existential enlightenment [tilværelsesoplysning] - are a further development of Gr’s philosophy of life-enlightenment. He thus sees Løgstrup as giving a contemporary currency to both Gr and the experiment at Testrup.The modernist critique which Birkelund formulates in Livs-Oplysning is carried further in the recently published anthology Eksistens og livsfilosofi [Existence and Life-philosophy], edited by Birkelund. Here a series of prominent Danish and Swedish scholars present some of the most epochmaking Danish, Swedish, German and French life-philosophers. The book works within the same framework of a pre-scientific perspective upon life as Livs-Oplysning: life is more than theories about life. It is this ‘more,’ this existential supervention, which life-philosophy endeavours to embrace, and it is the relevance of this life-perspective to the whole field of educational, social and health concerns that this book desires to assert. Among the lifephilosophers selected for presentation, Løgstrup and Gr. again appear along with, to name only a few, Jakob Knudsen, Hans Lipps, Søren Kierkegaard, Martin Buber and Hannah Arendt.Again, we are dealing with an important book which offers inspiring reading: but the book has its weak points. The foreword proposes that lifephilosophy rests upon a revolt against the overdominance of rationalism: but is this an adequate characterisation of life-philosophy? is it sufficiently discriminating to call both Løgstrup and Kierkegaard life-philosophers? Løgstrup himself (Opgør med Kierkegaard [Confrontation with Kierkegaard^) has argued that life-philosophy in many ways entails a confrontation with (Kierkegaard’s) existential philosophy. While both life-philosophy and existential philosophy represent a showdown with the rationalism cultivated by Enlightenment philosophers, they go about it in diverse ways.
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Jügel, Thomas. "Repetition analysis function (ReAF) I." Indogermanische Forschungen 120, no. 1 (October 16, 2015): 177–208. http://dx.doi.org/10.1515/if-2015-0010.

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Abstract Repetitions are relevant for several aspects of historical philology. With regard to Avestan, they may allow for the identification of ceremonial frames or opening and closing sections revealing the compositional structure of a ceremony. In case of manuscript comparison, the question arises whether a variant appears only once or in all of its repetitive passages. Furthermore, by analysing the compositional structure we may be able to detect ceremonial structures different to the practice of today. A secondary aspect relates to the interpretation of the grammaticality of Young Avestan passages. The repetition analysis provides evidence that passages which are hitherto considered ill-formed actually follow the rules of Avestan grammar. The scope of this study is to investigate computational means for detecting repetitive sequences. It represents a case study of the manuscript J2 by means of tools that were set up in the LOEWE priority programme Digital Humanities at the Goethe University Frankfurt am Main: a digital lexicon, a letter discrimination matrix for Avestan, and the programme Repetition Analysis Function. The article ReAF I offers some basic observations on repetitive sequences in the manuscript J2 and lays the foundation for ReAF II (Jügel forthc.), where the results of the repetition analyses will be used to discuss the compositional structure of the Yasna.
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Reitter, Anke, Norman Doehring, Zerrin Maden, Phillip A. Hessler, and Björn Misselwitz. "Ist eine eigenständige Geburtshilfe in einem Haus der Grund- und Regelversorgung sinnvoll und führt sie zu messbaren Veränderungen in der Versorgung?" Zeitschrift für Geburtshilfe und Neonatologie 223, no. 03 (December 7, 2018): 147–56. http://dx.doi.org/10.1055/a-0749-9024.

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Zusammenfassung Einleitung Eine eigenständig, konzeptionell neu ausgerichtete Geburtshilfe in einem Haus der Grund- und Regelversorgung kann innerhalb kurzer Zeit Veränderungen in der Versorgungsqualität zeigen. Material und Methode Die geburtshilflichen Daten eines Krankenhauses mit einer Geburtshilfe der Versorgungstufe (VS) IV (VS IV) in Frankfurt, Deutschland werden untersucht. Im Vergleich werden ausgewählte Daten aus der externen stationären Qualitätssicherung (EsQS) von 2013 (gemeinschaftliche geburtshilfliche und gynäkologischen Abteilung) vs. 2016 (eigenständige Geburtshilfe) vorgestellt. Ergebnisse Die Geburtenzahl ist im Untersuchungszeitraum um 46,4% (von 803 Geburten auf 1176 Geburten) angestiegen. Die Gesamtsectiorate sank um 8,9 von 34,9% auf 26% (p<0,01). Die vaginal operativen Geburten stiegen um 5,2% (p<0,01). Die Verlegungsrate von Neonaten sank von 5,6 auf 3,1% (p<0,01). Die Interventionen Einleitung (10,1 auf 9,4%; p=0,632) und Episiotomierate (13,4 auf 1,1%; p<0,01) sind gesunken. Die Rate der peripartalen schweren Azidosen ist von keinem Fall in 2013 auf 2 Fälle in 2016 angestiegen (p<0,05). Bei der Anzahl an Erst-Sectiones und der Rate an Re-Sectio zeigt sich ein nicht-signifikanter fallender Trend. Schlussfolgerung Die Schaffung einer chefärztlich geleiteten geburtshilflichen Abteilung an einem Haus der Grund- und Regelversorgung kann innerhalb kurzer Zeit zu messbaren Veränderungen und Qualitätssteigerungen in der Versorgung führen.
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42

Langenbacher, Eric, and Friederike Eigler. "Memory Boom or Memory Fatigue in 21st Century Germany?" German Politics and Society 23, no. 3 (September 1, 2005): 1–15. http://dx.doi.org/10.3167/104503005780979976.

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Is "memory fatigue" setting in? One often hears this question in regards to Germans whenever another Holocaust-centered or Nazi era memory event erupts. But, one also increasingly hears this question about intellectuals and scholars in the humanities. Political scientists, lamentably, never really got into the study of memory in the first place. As an overly qualitative phenomenon the study of collective memory was impervious to dominant quantitative or rationalist methodologies in the discipline. Like culture more generally, it was considered either a default category or an irrelevant factor for the core of political analysis—interests and institutions—and was best left to the humanities or sociology. Others have argued that memory never really mattered at all for the vast majority of Germans who are interested in the consumerist present or for a proper understanding of the political system. At the most, it concerned only a small circle of the German elite and media such as the feuilleton section of the Frankfurter Allgemeine Zeitung and Der Spiegel, and, certain German studies centers and journals in the USA.
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43

Abraham, Aby, Jinu George, Elbe Peter, Koshi Philip, Rajesh Chankramath, Dexton Antony Johns, and Anitha Bhaskar. "Establishment of a new relationship between posed smile width and lower facial height: A cross-sectional study." European Journal of Dentistry 09, no. 03 (July 2015): 394–99. http://dx.doi.org/10.4103/1305-7456.163232.

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ABSTRACT Objective: The present study is intended to add a new parameter that would be useful in orthodontic clinical evaluation, treatment planning, and determination of vertical dimension (at occlusion). Materials and Methods: Standardized videographic recording of 79 subjects during posed smile was captured. Each video was then cut into 30 photos using the free studio software. The widest commissure-to-commissure posed smile frame (posed smile width [SW]) was selected as one of 10 or more frames showing an identical smile. Lower third of the face is measured from subnasale to soft tissue menton using a digital vernier caliper. Two values were then compared. Ratio between lower facial height and posed SW was calculated. Results: The co-relation between smiling width and lower facial height was found to be statistically significant (P < 0.01). The ratio of lower facial height and smiling width was calculated as 1.0016 with a standard deviation (SD) = 0.04 in males and 1.0301 with an SD = 0.07 in females. The difference between the mean lower facial height in males and females was statistically significant with a t = 10.231 and P = 0.000. The difference between the mean smiling width in males and females was also statistically significant with a t = 5.653 and P = 0.000. Conclusion: In class I subjects with pleasing appearance, normal facial proportions, normal overjet and overbite, and average Frankfort mandibular angle, the lower facial height (subnasale to soft tissue menton) is equal to posed SW.
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Balachandran, Rajiv, Om Prakash Kharbanda, Karthik Sennimalai, and Bala Chakravarthy Neelapu. "Orientation of Cone-Beam Computed Tomography Image: Pursuit of Perfect Orientation Plane in Three Dimensions—A Retrospective Cross-Sectional Study." Annals of the National Academy of Medical Sciences (India) 55, no. 04 (October 2019): 202–9. http://dx.doi.org/10.1055/s-0040-1701144.

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Abstract Objective This study aimed to evaluate the reproducibility of nine reference planes used in orientation of as-received cone-beam computed tomography (CBCT) images in all three dimensions. Materials and Methods The study was conducted on CBCT images of 15 adult subjects (mean age 21.2 ± 5.8 years). The anonymized CBCT images were oriented using five different methods created from nine reference planes by two experienced orthodontists. For each subject, pitch, yaw, and roll changes with five orientation methods were recorded twice by each observer. Statistical Analysis The inter- and intraobserver agreement was tested using intraclass correlation (ICC) and Bland–Altman plot. The intra- and interobserver error was analyzed using paired t-test. Analysis of variance and paired t-test were used to analyze the differences among the various pitch, roll, and yaw orientation planes. Results Inter- and intraobserver agreement (ICC, 0.9) was excellent for all the nine reference planes. The interobserver reliability showed statistically significant differences for four planes namely Frankfort horizontal plane constructed on right side (p = 0.014) and left side (p = 0.000), transorbital plane (p = 0.001), and midsagittal plane on top view (p = 0.036); however, the mean differences were clinically insignificant. Conclusion The landmark-based nine reference planes used in this study to orient CBCT images showed good reproducibility. Therefore, these reference planes can be used to orient CBCT images and can be incorporated into automated software.
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Yan, Zhe-Bin, Yi-Dan Wan, Chu-Qiao Xiao, Ya-Qi Li, Yu-Yao Zhang, Yang An, and Xin Xiong. "Craniofacial Morphology of Orthodontic Patients with and without Temporomandibular Disorders: A Cross-Sectional Study." Pain Research and Management 2022 (March 22, 2022): 1–11. http://dx.doi.org/10.1155/2022/9344028.

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Purpose. We aimed to explore the relationship between temporomandibular disorders (TMDs) and craniofacial morphology in orthodontic patients. Methods. Altogether, 262 orthodontic patients were included and divided into two groups according to their Fonseca Anamnestic Index (FAI) scores: a no-TMD group (control group, FAI < 20) and a TMD group (FAI ≥ 20). Cephalometric parameters including cranial, maxillary, mandibular, and dental parameters were traced on cephalograms. Craniofacial morphology was compared between TMD and control groups, followed by subgroup analyses based on TMD severity, gender, age, and temporomandibular joint (TMJ) symptoms. Results. The prevalence of TMDs was 52.7% among included patients (138/262). The mean age of TMD patients was higher than that of the control group. No significant difference in gender distribution between the groups was observed. The most commonly reported FAI items were misaligned teeth, neck pain, and emotional tension. The Frankfort-mandibular plane angle (FMA) was larger in the TMD patients than in the control group, whereas no significant differences in other parameters were observed. Subgroup analysis based on TMD severity revealed that FMA and anterior facial height of moderate/severe TMD patients were significantly larger than those of mild or no-TMD patients. Among male patients, the anterior cranial base length was smaller, and the anterior facial height was larger in the TMD group. Among female patients, no significant differences in craniofacial morphology between the groups were observed. In juvenile patients, overjet and overbite were smaller in the TMD group. In adult patients, SNA, ANB, FMA, and gonial angle were larger in the TMD group. Within the TMD group, patients with TMJ pain or noises exhibited characteristic craniofacial features compared to patients without these symptoms. Conclusions. Orthodontic patients with TMDs have specific craniofacial morphology, suggesting a relationship between TMDs and particular craniofacial features in orthodontic patients.
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Hyvönen, Ari-Elmeri. "Careless Speech: Conceptualizing Post-Truth Politics1." New Perspectives 26, no. 3 (October 2018): 31–55. http://dx.doi.org/10.1177/2336825x1802600303.

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The notion of post-truth politics has been insufficiently conceptualized, leaving its empirical viability questionable. As a response to this uncertainty, I seek to elaborate a concept of post-truth politics by comparing facts to public infrastructure, which I understand in an Arendtian fashion: as a condition that both limits and enables opinionated debate. I put forward an understanding of post-truth as a two-sided process brought about by mutually dependent structural factors contributing to the irrelevance of factual truths and a particular political style labelled careless speech. I place post-truth in a historical context and seek to distinguish it, particularly, from Harry Frankfurt's ‘bullshit’. Bullshit works within the mindset of carefully crafted advertisement-speak. Careless speech seeks to create confusion and bring democratic debate to a halt. I also explicate some key economic, cultural, and media-related factors that contribute to the emergence of post-truth politics. The third section discusses effective practices of conveying truth in the public sphere. I critically analyze fact-checking, (Foucauldian) fearless speech ( parrhesia) and storytelling, contrasting them to ‘careless speech’, and emphasize the need to address political structures in addition to more epistemologically-oriented solutions. I conclude with reflections on the economic-cultural background to factual infrastructure's disrepair, and highlight some future lines of inquiry in IR and Political Science.
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Barth, Janina, and Andrea H. Schneider-Braunberger. "Nutzen von Erfahrungswissen in Krisen." Zeitschrift für Unternehmensgeschichte 66, no. 1 (March 1, 2021): 119–39. http://dx.doi.org/10.1515/zug-2020-0033.

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Abstract It appears to be almost self-evident that most people look towards past experiences for guidance during times of crisis. We would like to consider the empirical evidence for this assumption by analysing the public discourse regarding the reactions to crises, which includes general reporting, statements from politicians or discussions in the media. The outbreak of the Corona pandemic in Germany, starting in March 2020, opens the possibility to collect several preliminary findings by analysing relevant press coverage in the newspapers. Articles from different sections of the Frankfurter Allgemeine Zeitung (F.A.Z.) and from the Handelsblatt were evaluated. As our main interest focuses on economic historical (not e. g. medical historical) research questions, we chose the F.A.Z. First, because its business reporting is important within the German newspaper environment in general. Second, because its reporting on the Corona pandemic was award-winning. Additionally, we focused on the Handelsblatt because the newspaper provides press coverage explicitly on financial, business, and political issues – all subjects directly affected by the Corona crisis. The analysis concluded that there was a rise in articles with historical references in general while the number of articles linked to businesses did not increase at the same time which can be linked to the absence of expert business history opinions on offer.
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48

Collins, T. F. X., T. N. Black, and D. I. Ruggles. "Developmental Toxicity of Orange B Given to Rats in Drinking Water." Toxicology and Industrial Health 11, no. 4 (July 1995): 387–97. http://dx.doi.org/10.1177/074823379501100402.

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Orange B, a pyrazolone dye used to color frankfurter and sausage casings, was given in distilled drinking water to pregnant Osborne-Mendel rats throughout gestation. Assessed on the basis of fluid consumption, the dose levels of 0, 0.05, 0.1, 0.2, and 0.4% corresponded to daily Orange B consumption of 0, 67.5, 129.6, 266.6, and 532.3 mg/kg body weight, respectively. On gestation day 20, the females were euthanized and cesarean sections were performed. Throughout gestation, the treated animals consumed less fluid than did the controls, but the decreases were not dose-related. Feed consumption and maternal weight gain were not affected. No dose-related changes were seen in maternal clinical findings, implantations, fetal viability, or fetal size (weight and length). No compound-related effects were seen in sternebral development. Ossification of the interparietal bones was reduced at some dose levels, but the decreases were considered random because of absence of dose response. No dose-related effect was seen in the incidence of skeletal variations in fetuses or in the number of litters containing fetuses with skeletal variations. Skeletal development, as measured by the average number of ossified vertebrae, was similar in all groups. Soft-tissue development was not affected by dose levels of 0.05 to 0.2%. In animals treated with 0.4% Orange B, significant increases were seen in the incidence of hydroureters (severe and moderate), in the average numbers of fetuses with at least one and at least two soft-tissue variations per litter, and in the percentage of litters containing fetuses with at least two soft-tissue variations.
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49

Weigelt, A., R. Ebinghaus, N. Pirrone, J. Bieser, J. Bödewadt, G. Esposito, F. Slemr, P. F. J. van Velthoven, A. Zahn, and H. Ziereis. "Tropospheric mercury vertical profiles between 500 and 10 000 m in central Europe." Atmospheric Chemistry and Physics Discussions 15, no. 20 (October 20, 2015): 28217–47. http://dx.doi.org/10.5194/acpd-15-28217-2015.

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Abstract. Measurements of the vertical distribution of atmospheric mercury (Hg) are rare, because airborne measurements are expensive and labour intensive. Consequently, only a few vertical Hg profile measurements have been reported since the 1970s. Besides the CARIBIC passenger aircraft observations, the latest vertical profile over Europe was measured in 1996. Within the Global Mercury Observation System (GMOS) project four vertical profiles were taken on board research aircraft (CASA-212) in August 2013 in background air over different locations in Slovenia and Germany. Each vertical profile consists of at least seven 5 min horizontal flight sections from 500 m above ground to 3000 m a.s.l. Gaseous elemental mercury (GEM) was measured with a Tekran 2537X analyser and a Lumex RA-915-AM. Total gaseous mercury (TGM) was measured using a Tekran 2537B analyser and gaseous oxidized mercury (GOM) was sampled onto 8 denuders for post flight analysis (one for each profile, three during the transfer flights, and two blanks). In addition to the mercury measurements, SO2, CO, O3, NO, NO2, as well as basic meteorological parameters (pressure, temperature, relative humidity) have been measured. Additional ground based speciated mercury measurements at the GMOS master site in Waldhof (Germany) were used to extend the profile to the ground. No vertical gradient was found inside the well mixed boundary layer (variation by less than 0.1 ng m-3) at different sites with GEM varying from location to location between 1.4 and 1.6 ng m-3 (STP; standard conditions: p = 1013.25 hPa, T = 273.15 K). At all locations GEM dropped to 1.3 ng m-3 (STP) when entering the free troposphere and remained constant at higher altitudes. The combination of the vertical profile, measured on 21 August 2013, over Leipzig (Germany) with the CARIBIC measurements during ascent and descent to Frankfurt airport (Germany) at approximately the same time provide a unique central European vertical profile from inside the boundary layer (550 m a.s.l.) to the upper free troposphere (10 500 m a.s.l.) and shows a fairly constant free tropospheric TGM concentration of 1.3 ng m-3 (STP). The highest GOM concentrations of up to 60 pg m-3 (STP, denuder samples) were found above the boundary layer during the transfer flights.
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50

Engels, K., P. Moll, P. Harter, A. Du Bois, A. Fisseler-Eckhoff, F. Kommoss, M. Kaufmann, and S. Loibl. "VEGF-A and COX-2 expression correlate with platinum resistance in ovarian cancers." Journal of Clinical Oncology 24, no. 18_suppl (June 20, 2006): 5062. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.5062.

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5062 Background: Regulators of angiogenesis such as VEGF-A and cell cycle such as p53 and COX-2 influence tumor behavior and response to chemotherapy. Methods: 114 patients with primary ovarian cancer treated in Frankfurt or Wiesbaden between 1999 and 2004 were examined. Primary surgery was followed by a platinum and taxane based chemotherapy in all patients. Expression of i-NOS, COX-2, VEGF-A, HIF-1 alpha was analyzed immunohistochemically using tissue micro arrays of primary tumor samples. Results were scored according to staining intensity and percentage of positive tumor cells resulting in an immune-reactive score (IRS) from 0 to 12. Vascularity was assessed using the Chalkley-Grid method after highlighting vessels with CD34 antibodies in whole tissue sections. These results were correlated with classical prognostic factors and survival. Non-parametric correlations were done using Spearman’s rho, correlations were significant at the 0,05 level (2-tailed). Results: The median age at the time of surgery was 63y (33–89y). The majority of the patients (85%) had advanced disease (FIGO III-IV). Tumor grading was G1 in 2%, G2 in 37%, and G3 in 61%. Expressions were as follows: i-NOS 60% positive (IRS ≥4); COX-2 50% positive (IRS ≥5); VEGF-A 50% strong (IRS ≥8), 32% moderate (IRS 4–7), 18% weak (IRS ≤4); HIF-1 alpha 37% positive (IRS ≥3), p53 33% weak (IRS ≤4), 67% strong (IRS >4); vascularity 41% low (≤5), 52% moderate (6–9), 7% high (>9). I-NOS correlated positively with COX-2 (p = 0,03), VEGF-A (p = 0,05), and p53 (p = 0,01). Grading correlated positively with HIF-1 alpha (p = 0,02) and vascularity (p = 0,01). Up to now none of the new parameters did show correlations with recurrence free survival (median follow-up 36 months). Platinum resistant tumors (time from primary diagnosis to relapse <12 months) were significantly more often negative for VEGF-A (p = 0,005) and COX-2 (p = 0,02). Conclusions: I-NOS correlates with markers of angiogenesis and cell cycle regulation. VEGF-A and COX-2 expression might predict platinum resistance in ovarian cancers. No significant financial relationships to disclose.
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