Journal articles on the topic 'Secondary Victoria Case studies'
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Battams, Samantha, Toni Delany-Crowe, Matt Fisher, Lester Wright, Anthea Krieg, Dennis McDermott, and Fran Baum. "Applying Crime Prevention and Health Promotion Frameworks to the Problem of High Incarceration Rates for Aboriginal and Torres Strait Islander Populations: Lessons from a Case Study from Victoria." International Indigenous Policy Journal 12, no. 2 (May 14, 2021): 1–29. http://dx.doi.org/10.18584/iipj.2021.12.2.10208.
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This article examines what kinds of policy reforms are required to reduce incarceration rates of Aboriginal and Torres Strait Islander people through a case study of policy in the Australian state of Victoria. This state provides a good example of a jurisdiction with policies focused upon, and developed in partnership with, Aboriginal communities in Victoria, but which despite this has steadily increasing incarceration rates of Indigenous people. The case study consisted of a qualitative analysis of two key justice sector policies focused upon the Indigenous community in Victoria and interviews with key justice sector staff. Case study results are analysed in terms of primary, secondary, and tertiary crime prevention; the social determinants of Indigenous health; and recommended actions from the Ottawa Charter for Health Promotion. Finally, recommendations are made for future justice sector policies and approaches that may help to reduce the high levels of incarceration of Aboriginal and Torres Strait Islander people.
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Fehlberg, Trafford, John Rose, Glenn Douglas Guest, and David Watters. "The surgical burden of disease and perioperative mortality in patients admitted to hospitals in Victoria, Australia: a population-level observational study." BMJ Open 9, no. 5 (May 17, 2019): e028671. http://dx.doi.org/10.1136/bmjopen-2018-028671.
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ObjectivesComprehensive reporting of surgical disease burden and outcomes are vital components of resilient health systems but remain under-reported. The primary objective was to identify the Victorian surgical burden of disease necessitating treatment in a hospital or day centre, including a thorough epidemiology of surgical procedures and their respective perioperative mortality rates (POMR).DesignRetrospective population-level observational study.SettingThe study was conducted in Victoria, Australia. Access to data from the Victorian Admitted Episodes Dataset was obtained using the Dr Foster Quality Investigator tool. The study included public and private facilities, including day-case facilities.ParticipantsFrom January 2014 to December 2016, all admissions with an International Statistical Classification of Diseases-10 code matched to the Global Health Estimates (GHE) disease categories were included.Primary and secondary outcome measuresAdmissions were assigned a primary disease category according to the 23 GHE disease categories. Surgical procedures during hospitalisations were identified using the Australian Refined Diagnosis Related Groups (AR-DRG). POMR were calculated for GHE disease categories and AR-DRG procedures.ResultsA total of 4 865 226 admitted episodes were identified over the 3-year period. 1 715 862 (35.3%) of these required a surgical procedure. The mortality rate for those undergoing a procedure was 0.42%, and 1.47% for those without. The top five procedures performed per GHE category were lens procedures (162 835 cases, POMR 0.001%), caesarean delivery (76 032 cases, POMR 0.01%), abortion with operating room procedure (65 451 cases, POMR 0%), hernia procedures (52 499 cases, POMR 0.05%) and other knee procedures (47 181 cases, POMR 0.004%).ConclusionsConditions requiring surgery were responsible for 35.3% of the hospital admitted disease burden in Victoria, a rate higher than previously published from Sweden, New Zealand and the USA. POMR is comparable to other studies reporting individual procedures and conditions, but has been reported comprehensively across all GHE disease categories for the first time.
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Yang Wang, Wilfred. "COVID-19 Contact Tracing and the Operationalisation of Somatechnics." Somatechnics 12, no. 1-2 (August 2022): 92–103. http://dx.doi.org/10.3366/soma.2022.0379.
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This article draws on the paradigm of media operationalism to understand the somatechnical construction of bodies during the COVID-19 pandemic. According to the concept of somatechnics, one’s experience with the social world is articulated through the available technologies and techniques required to and developed from using these technologies ( Sullivan and Murray 2016 ). By drawing on the case of the Service Victoria app, the digital COVID-19 contact tracing system launched by the Victoria State government in Australia, I focus on the transformative meaning of technologies and somatechnics and how subjectivity is being redefined through the lens of technological utilisation. I suggest that all human-related forms of relations (human-to-human and human-to-machine) have become secondary and give way to the synchronic data-to-data relation of the app. In the regime of operational media, the body is not just a historical and cultural construction but a techno-transactional object that supports the optimisation of automated-decision making. The recent operational-turn in media studies provides a useful pathway to rethink the changing meaning of body and the human/technologies entanglement.
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Sala, Florin, Alin Dobrei, and Mihai Valentin Herbei. "Leaf Area Calculation Models for Vines Based on Foliar Descriptors." Plants 10, no. 11 (November 13, 2021): 2453. http://dx.doi.org/10.3390/plants10112453.
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In the case of foliar area studies on vines, with a large number of determinations, a simple, fast, sufficiently accurate and low-cost method is very useful. The typology of leaves on the vine is complex, characterized by several descriptive parameters: median rib; secondary venations of the first and second order; angles between the median rib and the secondary venations; sinuses; length and width of the leaf. The present study aimed to evaluate models for calculating the leaf area based on descriptive parameters and KA (KA as the surface constant used to calculate the leaf area) for six vine cultivars, ‘Cabernet Sauvignon’ (CS), ‘Muscat Iantarnîi’ (MI), ‘Muscat Ottonel’ (MO), ‘Chasselas’ (Ch), ‘Victoria’ (Vi) and ‘Muscat Hamburg’ (MH). The determined KA surface constants had subunit values (0.91 to 0.97), except for the cultivars ‘Muscat Iantarnîi’ and ‘Muscat Ottonel’ where the surface constant KA2 (in relation to the second-order secondary venations) had supraunitary values (1.07 and 1.08, respectively). The determination of the leaf area was possible under different conditions of statistical accuracy (R2 = 0.477, p = 0.0119, up to R2 = 0.988, p < 0.001) in relation to the variety and parametric descriptors considered. The models obtained from the regression analysis facilitated a more reliable prediction of the leaf area based on the elements on the left side of the leaf, in relation to the median rib, compared to those on the right. The accuracy of the results was checked on the basis of minimum error (ME) and confirmed by parameters R2, p and RMSE.
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Smith, Peter. "O2C.3 What predicts a secondary absence following return to work among workers’ compensation claimants in victoria? Results from a longitudinal cohort." Occupational and Environmental Medicine 76, Suppl 1 (April 2019): A16.2—A16. http://dx.doi.org/10.1136/oem-2019-epi.43.
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Time taken to first return to work (RTW) is often a primary endpoint for studies among injured workers. However, studies using administrative workers’ compensation claims data have documented that a substantial proportion (approximately one half) of claimants will incur a subsequent period of wage replacement. Unfortunately, workers’ compensation data is limited in the information collected to better understand which claimants are more likely to have a subsequent absence from work. The objective of this study is to address this gap using a cohort of workers’ compensation claimants in the Australian state of Victoria.The sample for this study is drawn from a longitudinal cohort of workers’ compensation claimants (n=869). For the purpose of this analysis we focused on those claimants who had returned to work (self-reported) at the baseline interview, which was conducted approximately 4 months after the injury had occurred (n=372). Independent variables examined included if the respondent was working on full or partial duties, currently receiving health care for their injury, type of injury (musculoskeletal versus psychological), co-worker responses when they returned to work (measured using nine questions), and work limitations, measured using an abbreviated form of the work limitations questionnaire.A total of 205 respondents (55% of the sample) reported a subsequent absence from work when interviewed 6 months later. All independent variables, with the exception of injury type, were associated with subsequent absences from work. In a multivariable model, only working modified duties and greater limitations remained statistically significant.The results of the current study help inform our understanding of trajectories in RTW and factors, measured after the first RTW, which may be associated with a subsequent absence from work. These findings can be integrated into RTW programs to help more workers achieve sustainable RTW following a work injury.
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Warren, Heather A. "Character, Public Schooling, and Religious Education, 1920-1934." Religion and American Culture: A Journal of Interpretation 7, no. 1 (1997): 61–80. http://dx.doi.org/10.1525/rac.1997.7.1.03a00030.
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Over the past five years, the American public has witnessed a flurry of interest in “character” and “character or moral education.” In 1992, William Kilpatrick wrote a book that attracted widespread attention, Why Johnny Can't Tell Right from Wrong: Moral Illiteracy and the Case for Character Education. A year later, William Bennett's best-selling anthology of remedial readings appeared, The Book of Virtues. More recently, Gertrude Himmelfarb published a book on the Victorian golden age of morals. At the same time, within the educational field, a subprofession of consultants devoted to character work has aimed to affect schooling at the elementary and secondary levels. As early as the mid-1970's, theologians and ethicists began discussing the idea of character, taking their cue from Stanley Hauerwas. Common to all of these writers is the belief that character has a necessary tie to religion and democracy.
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O'Dea, Molly, Amy Cosby, Jaime Manning, Nicole McDonald, and Bobby Harreveld. "Industry perspectives of industry school partnerships: What can agriculture learn?" Australian and International Journal of Rural Education 32, no. 3 (November 18, 2022): 1–21. http://dx.doi.org/10.47381/aijre.v32i3.334.
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This paper aims to identify and synthesise research related to industry perspectives of industry school partnerships (ISPs) with primary and secondary students globally. A systematic review of ISP studies published between 2001 and 2021 that included industry perspectives was undertaken in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol. This focused systematically ordered review of industry perspectives of ISPs elicited four key findings: Limited research specifically focusing on industry participants’ perceptions of career and knowledge sharing ISPs exist. The most common reasons for participation included promoting careers and/or their industry, and enhancing community goodwill. The most common barriers or challenges in participating included time, budget and process constraints, and understanding the partnership’s impact. Communication, trust, relationships, and setting clear goals are often important features highlighted for successful partnerships. The recommendations from this review will be used to design, deliver and evaluate ISPs which aim to benefit agricultural industry participants. Future research will apply the findings from this review to a rural case site in Victoria, Australia, focused on agricultural ISPs aimed at increasing students’ aspirations for a career in the sector. This is vital as agriculture is an important industry in this region, yet many students are unaware of the range of career opportunities available to them.
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Escalante, V., G. Moeller, and A. Rivas. "Pond evaluation and upgrading in Mexico." Water Science and Technology 42, no. 10-11 (November 1, 2000): 43–50. http://dx.doi.org/10.2166/wst.2000.0605.
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Half of the wastewater facilities constructed in Mexico for wastewater treatment and projected to be constructed in the next ten years, are waste stabilisation pond systems. The existing facilities have several problems in their operation. A national programme was developed by federal and local authorities responsible for sanitation and treatment for the monitoring and evaluation of the existing pond systems. The aim of the programme was the monitoring and evaluation of pond performance and effluent quality of a number of waste stabilisation ponds systems in different regions in Mexico and to upgrade and expand them if necessary. The programme was developed during 1998 and the specific sites selected were distributed within the country in the southern, central and northern part of Mexico. The evaluation of the specific ponds led to the production of a series of case studies on the various pond systems selected, that were discussed and jointly developed with local technicians in charge of the operation of the facilities. The case studies developed were: Gómez Portugal pond system located in the state of Aguascalientes, constituted by a baffled facultative pond; Guadalupe Victoria pond system located inthe State of Durango and constituted by a primary facultative, a secondary facultative and a third facultative pond; La Reforma pond system in Sinaloa, with two facultative ponds in series; González Ortega pond system in the State of Baja California Norte, with four anaerobic and four facultative ponds, and Chapilla pond system, located in the state of Chiapas. Plant effluents are intended for several purposes: irrigation and for discharge into receiving bodies. Effluent quality complies only with BOD limits, but not with microbiological limits established in national standards. For each pond, an upgrading plan is presented to comply with microbiological standards for discharge or for its use in irrigation.
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Katusiime, Juliet, and Brigitta Schütt. "Towards Legislation Responsive to Integrated Watershed Management Approaches and Land Tenure." Sustainability 15, no. 3 (January 25, 2023): 2221. http://dx.doi.org/10.3390/su15032221.
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Land tenure affects integrated watershed management approaches in various ways, such as influencing land use and investment in sustainability practices and decisions. However, some land tenure and integrated watershed management relations need more examination, including how the prevailing relevant legislation responds and the needed course of action. In this paper, we provide relevant evidence to support a shift to responsive actions and legislation through (a) examining land tenure scenarios affecting integrated watershed management, including the public–private land tenure co-existence from a watershed perspective; (b) the responsiveness of the prevailing relevant legislation to integrated watershed management and the land tenure scenarios and (c) identifying legislative remedies recommendable for responsiveness. We use qualitative methods to review secondary data sources, including four legislations, and complement them with field survey data. Field experiences are from three sub-catchments in the Lake Victoria basin, each representing a different land tenure system, as case studies. Land tenure links with integrated watershed management in various ways, such as influencing land use decisions. However, underscoring the relationship from the private and public land tenure perspective also indicates a complex and tense spatial relationship. As such, it likely limits adopting sustainable land use and management practices in watersheds as a case. Regardless, the perceptions from the study area indicate the land tenure systems and forms enabling sustainable choices and decisions, despite limitations such as tenure insecurity. The disconnect between integrated watershed management aspirations of ensuring sustainability, the land tenure abilities and the subsequent human practices is mainly institutional, with the relevant legislation indicating a low to moderate level of responsiveness to integrated watershed management approaches and land tenure, thus, abating effectiveness. Therefore, we suggest a shift towards responsive programming and legislation and the adoption of model legislation to support responsiveness replication. We also recommend further studies to assess the legal gaps and feasibility thereof.
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Carlton, Caroline, Jacqueline M. Norris, Evelyn Hall, Michael P. Ward, Stephanie Blank, Shelby Gilmore, Anjuli Dabydeen, Vivian Tran, and Mark E. Westman. "Clinicopathological and Epidemiological Findings in Pet Cats Naturally Infected with Feline Immunodeficiency Virus (FIV) in Australia." Viruses 14, no. 10 (September 30, 2022): 2177. http://dx.doi.org/10.3390/v14102177.
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Feline immunodeficiency virus (FIV) infection in experimentally infected domestic cats produces characteristic clinical manifestations including hematological changes, neurological disease, neoplasia (most notably lymphoma) and lymphopenia-mediated immunodeficiency predisposing cats to a range of secondary infections. Conflicting reports exist, however, with regard to disease associations and survival time in naturally FIV-infected cats. The purpose of this retrospective case–control study was to investigate the effect of natural FIV infection on hematological, blood biochemical and urinalysis parameters and survival time in three cohorts of pet cats in Australia. Cohorts 1 and 2 were recruited from a large veterinary hospital in Melbourne, Victoria (n = 525 and 282), while a third cohort consisted of cats recruited from around Australia as part of a FIV field vaccine efficacy trial (n = 425). FIV-infected cats in cohorts 1, 2 and 3 were found to have 15/37 (41%), 13/39 (33%) and 2/13 (15%) clinicopathological parameters significantly different to FIV-uninfected cats, respectively. Two changes in FIV-infected cats in cohort 1, hypochromia (low hemoglobin) and hyperglobulinemia, were outside the supplied reference intervals and should serve as diagnostic triggers for FIV testing. Kaplan–Meier survival analysis of cats in cohorts 1 and 2 combined did not find any difference between FIV-infected and FIV-uninfected cats, however a confounding factor was a large euthanasia rate within the first 12 months in both groups. Three significant (p < 0.05) spatial clusters of FIV infection were identified in Melbourne. A possible relationship between FIV infection status and socioeconomic disadvantage was discovered, based on three government indices of socioeconomic status (p < 0.001). Until longitudinal field studies are performed in Australia to further investigate the long-term effects of natural FIV infection, Australian veterinarians should consider FIV to be an important infection of pet cats, and recommend measures to prevent FIV infection.
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Bizino, Maurice B., Ingrid M. Jazet, Paul de Heer, Huub J. van Eyk, Ilona A. Dekkers, Patrick C. N. Rensen, Elisabeth H. M. Paiman, Hildebrandus J. Lamb, and Johannes W. Smit. "Placebo-controlled randomised trial with liraglutide on magnetic resonance endpoints in individuals with type 2 diabetes: a pre-specified secondary study on ectopic fat accumulation." Diabetologia 63, no. 1 (November 5, 2019): 65–74. http://dx.doi.org/10.1007/s00125-019-05021-6.
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Abstract Aims/hypothesis The aim of this work was to assess the effect of liraglutide on ectopic fat accumulation in individuals with type 2 diabetes mellitus. Methods This study is a pre-specified subanalysis of the MAGNetic resonance Assessment of VICTOza efficacy in the Regression of cardiovascular dysfunction In type 2 diAbetes mellitus (MAGNA VICTORIA) study, with primary endpoints being the effects of liraglutide on left ventricular diastolic and systolic function. The MAGNA VICTORIA study was a single-centre, parallel-group trial in 50 individuals with type 2 diabetes mellitus (BMI >25 kg/m2) who were randomly assigned (1:1, stratified for sex and insulin use) to receive liraglutide 1.8 mg once daily or placebo for 26 weeks, added to standard care. Participants, study personnel and outcome assessors were blinded to treatment allocation. The secondary endpoints of visceral adipose tissue (VAT), abdominal subcutaneous adipose tissue (SAT) and epicardial fat were measured with MRI. Hepatic triacylglycerol content (HTGC) and myocardial triacylglycerol content (MTGC) were quantified with proton MR spectroscopy. Between-group differences (change from baseline) were tested for significance using ANCOVA. Mean differences with 95% CIs were reported. Results The trial was completed in 2016. Twenty-four participants were randomised to receive liraglutide and 26 to receive placebo. One patient in the liraglutide group withdrew consent before having received the study drug and was not included in the intention-to-treat analysis. Liraglutide (n = 23) vs placebo (n = 26) significantly reduced body weight (liraglutide 98.4 ± 13.8 kg to 94.3 ± 14.9 kg; placebo 94.5 ± 13.1 kg to 93.9 ± 13.2 kg; estimated treatment effect −4.5 [95% CI −6.4, −2.6] kg). HbA1c declined in both groups without a significant treatment effect of liraglutide vs placebo (liraglutide 66.7 ± 11.5 mmol/mol to 55.0 ± 13.2 mmol/mol [8.4 ± 1.1% to 7.3 ± 1.2%]; placebo 64.7 ± 10.2 mmol/mol to 56.9 ± 6.9 mmol/mol [8.2 ± 1.0% to 7.5 ± 0.7%]; estimated treatment effect −2.9 [95% CI −8.1, 2.3] mmol/mol or −0.3 [95% CI −0.8, 0.2]%). VAT did not change significantly between groups (liraglutide 207 ± 87 cm2 to 203 ± 88 cm2; placebo 204 ± 63 cm2 to 200 ± 55 cm2; estimated treatment effect −7 [95% CI −24, 10] cm2), while SAT was reduced by a significantly greater extent with liraglutide than with placebo (liraglutide 361 ± 142 cm2 to 339 ± 131 cm2; placebo 329 ± 107 cm2 to 333 ± 125 cm2; estimated treatment effect −29 [95% CI −51, −8] cm2). Epicardial fat did not change significantly between groups (liraglutide 8.9 ± 4.3 cm2 to 9.1 ± 4.7 cm2; placebo 9.6 ± 4.1 cm2 to 9.6 ± 4.6 cm2; estimated treatment effect 0.2 [95% CI −1.5, 1.8] cm2). Change in HTGC was not different between groups (liraglutide 18.1 ± 11.2% to 12.0 ± 7.7%; placebo 18.4 ± 9.4% to 14.7 ± 10.0%; estimated treatment effect −2.1 [95% CI −5.3, 1.0]%). MTGC was not different after treatment with liraglutide (1.5 ± 0.6% to 1.2 ± 0.6%) vs placebo (1.3 ± 0.5% to 1.2 ± 0.6%), with an estimated treatment effect of −0.1 (95% CI −0.4, 0.2)%. There were no adjudicated serious adverse events. Conclusions/interpretation Compared with placebo, liraglutide-treated participants lost significantly more body weight. Liraglutide primarily reduced subcutaneous fat but not visceral, hepatic, myocardial or epicardial fat. Future larger studies are needed to confirm the results of this secondary endpoint study. Trial registration ClinicalTrials.gov NCT01761318. Funding This study was funded by Novo Nordisk A/S (Bagsvaerd, Denmark).
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Bramble, Tom. "Political Economy and Management Strategy in the Metal and Engineering Industry." Journal of Industrial Relations 31, no. 1 (March 1989): 22–45. http://dx.doi.org/10.1177/002218568903100102.
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The study of industrial relations management has been a long-neglected aspect of the Australian scene. Recent changes in the balance of power on the shop floor in the aftermath of prolonged recession in the metal and engineering industry, however, make such neglect an expensive luxury. This article looks at four aspects of management t strategy: the labour relations management function, relations with the unions at the workplace, attitudes to employee involvement, and attitudes to the employment relationship. The suggestion, in the light of secondary evidence and a series of fourteen case studies in the Victorian and New South Wales metal industry, is that three variables are important in helping to explain the direction that labour relations management has taken in recent years. These are the 'labour threat: the reorganization of production methods, and changes to the legal and institutional framework. It was found that management in those plants in which exposure to these three environmental pressures was similar responded with fairly similar labour relations management practices, suggesting that there may indeed be a link between the key variables.
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Benavent, D., M. Garrido-Cumbrera, C. Plasencia, L. Christen, H. Marzo-Ortega, J. Correa-Fernández, P. Plazuelo-Ramos, D. Webb, and V. Navarro-Compán. "AB0500 IMPACT OF COVID-19 PANDEMIC IN OVERALL HEALTH AND FUNCTIONING IN PATIENTS WITH AXIAL SPONDYLOARTHRITIS: RESULTS FROM THE REUMAVID STUDY (PHASE 1)." Annals of the Rheumatic Diseases 80, Suppl 1 (May 19, 2021): 1277.2–1278. http://dx.doi.org/10.1136/annrheumdis-2021-eular.2153.
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Background:Evidence on the impact of the COVID-19 pandemic on the overall health and functioning in patients with axial spondyloarthritis (axSpA) is scarce.Objectives:To analyse the impact of the COVID-19 pandemic on the overall health and functioning in patients with axSpA.Methods:Data from axSpA patients participating in the first phase of the REUMAVID study were analysed. REUMAVID is a cross-sectional, observational study collecting data through an online questionnaire of unselected patients with rheumatic and musculoskeletal diseases (RMDs), recruited by patient organizations. The survey was disseminated during the beginning of the COVID-19 pandemic (April-July 2020) in seven European countries (Cyprus, France, Greece, Italy, Portugal, Spain, and the United Kingdom). Patients with axSpA who completed the ASAS health index (ASAS-HI) questionnaire were included in this analysis. Descriptive analyses were used to present socio-demographic and clinical characteristics, as well as daily habits. Overall health and functioning were defined according to the ASAS-HI (0-17), as follows: good health (ASAS-HI ≤5), acceptable health (ASAS-HI 6-11), and poor health (ASAS-HI ≥12). As secondary outcomes, well-being (WHO-5), self-perceived health status, and HADS for anxiety and depression were assessed.Results:Out of 670 axSpA patients, 587 (87.6%) completed ASAS-HI. Of these, 70.4% were female, 72.6% were married or in a relationship, 46.7% had university studies and 37.6% were currently employed. Mean age was 49.9±12.8 years and mean BMI was 26.7±5.5. Regarding extraarticular manifestations, 13.6% had psoriasis, 12.1% inflammatory bowel disease and 18.7% uveitis. Before the COVID-19 pandemic, 50.9% were receiving biological drugs, 46.3% NSAIDs, 26.4% painkillers, 24.7% conventional DMARDs, and 11.9% oral corticosteroids. According to the ASAS-HI, 19.6 % of patients were classified as having poor health, with the most affected aspects being pain (92.0%), movement (86.5%), maintenance of body position (80.6%), energy (79.0%) and sleep (75.3%). Regarding self-perceived health status, 14% reported their health status as “bad” or “very bad”, and 46.8% reported worsening health during the pandemic (Table 1). A distribution of the results of the total ASAS-HI scores can be seen in Figure 1.Table 1.Overall health and well-being, disease activity, and mental health.Primary Outcome (ASAS-HI)Mean ± SD orn (%)ASAS-HI (0-17), n=5878.0 (±3.9)ASAS-HI <5 (good health)159 (27.1) 5-12 (acceptable health)313 (53.3) ≥12 (poor health)115 (19.6)Secondary OutcomesWHO-5 WHO-5, (0-100), n=58446.3 (±23.1) WHO- 5 Poor wellbeing WHO- ≤50330 (56.5)Self-perceived health status, n=585 Very good33 (5.6) Good214 (36.6) Fair256 (43.8) Bad69 (11.8) Very bad13 (2.2)Change in health status during lockdown, n=587 Much worse than before54 (9.2) Moderately worse220 (37.6) Same as before270 (46.0) Moderately better35 (6.0) Much better than before6 (1.0)HADSHADS Anxiety (0-21), n=5878.4 (±4.1)HADS Anxiety No case (0-7)248 (42.7) Borderline case (8-10)151 (26.0) Case (11-21)182 (31.3) HADS Depression (0-21), n=5877.0 (±4.3)HADS Depression No case (0-7)329 (56.6) Borderline case (8-10)134 (23.1) Case (11-21)118 (20.3)Figure 1.Distribution of the result of ASAS-HI scores (N= 587)Conclusion:One out of five patients with axSpA reported poor health and functioning according to the ASAS-HI, and almost half of patients reported worsening self-perceived health status during the first wave of the COVID-19 pandemic.Keywords: COVID-19, axial spondyloarthritis, ASAS-HI, healthDisclosure of Interests:Diego Benavent Grant/research support from: Abbvie, Novartis and Roche, Marco Garrido-Cumbrera: None declared., Chamaida Plasencia Grant/research support from: Pfizer, Sanofi, Novartis, Roche and Lilly, Laura Christen Employee of: Novartis Pharma AG, Helena Marzo-Ortega Grant/research support from: Abbvie, Celgene, Janssen, Elli-Lilly, Novartis, Pfizer, UCB and Takeda Pharmaceutical Company, José Correa-Fernández: None declared., Pedro Plazuelo-Ramos: None declared., Dale Webb: None declared., Victoria Navarro-Compán Grant/research support from: Abbvie, BMS, Lilly, MSD, Novartis, Pfizer, Roche, UCB.
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Goldfeld, Sharon, Hannah Bryson, Fiona Mensah, Anna Price, Lisa Gold, Francesca Orsini, Bridget Kenny, et al. "Nurse home visiting to improve child and maternal outcomes: 5-year follow-up of an Australian randomised controlled trial." PLOS ONE 17, no. 11 (November 28, 2022): e0277773. http://dx.doi.org/10.1371/journal.pone.0277773.
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Objectives Nurse home visiting (NHV) is widely implemented to address inequities in child and maternal health. However, few studies have examined longer-term effectiveness or delivery within universal healthcare systems. We evaluated the benefits of an Australian NHV program (“right@home”) in promoting children’s language and learning, general and mental health, maternal mental health and wellbeing, parenting and family relationships, at child ages 4 and 5 years. Setting and participants Randomised controlled trial of NHV delivered via universal, child and family health services (the comparator). Pregnant women experiencing adversity (≥2 of 10 risk factors) were recruited from 10 antenatal clinics across 2 states (Victoria, Tasmania) in Australia. Intervention Mothers in the intervention arm were offered 25 nurse home visits (mean 23·2 home visits [SD 7·4, range 1–43] received) of 60–90 minutes, commencing antenatally and continuing until children’s second birthdays. Primary and secondary outcomes measured At 4 and 5 years, outcomes were assessed via parent interview and direct assessment of children’s language and learning (receptive and expressive language, phonological awareness, attention, and executive function). Outcomes were compared between intervention and usual care arms (intention to treat) using adjusted regression with robust estimation to account for nurse/site. Missing data were addressed using multiple imputation and inverse probability weighting. Results Of 722 women enrolled in the trial, 225 of 363 (62%) intervention and 201 of 359 (56%) usual care women provided data at 5 years. Estimated group differences showed an overall pattern favouring the intervention. Statistical evidence of benefits was found across child and maternal mental health and wellbeing, parenting and family relationships with effect sizes ranging 0·01–0·27. Conclusion An Australian NHV program promoted longer-term family functioning and wellbeing for women experiencing adversity. NHV can offer an important component of a proportionate universal system that delivers support and intervention relative to need. Trial registration 2013–2016, registration ISRCTN89962120
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Wilson, C., G. Skaczkowski, P. Sanderson, M. Shand, and A. Byrne. "Triaging for Supportive Care Services: Do People Want and Accept Referral?" Journal of Global Oncology 4, Supplement 2 (October 1, 2018): 117s. http://dx.doi.org/10.1200/jgo.18.10300.
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Background: Distress is the 6th vital sign in cancer yet it is only assessed in an ad hoc way in most cancer services. The Distress Thermometer (DT) and the associated Problem Checklist (PC) are the most widely available tools although few studies report on how they are used to effectively triage services. Aim: To explore the link between distress assessment, problem identification, referral to specific supportive care services by staff, and service uptake by cancer patients and survivors among a sample of people attending a major cancer hospital in Victoria Australia. Methods: A secondary analysis of quality assurance audit data were undertaken using data collected from patient medical records between January 2013 and June 2014. Data extracted were; age, sex, post code, language spoken, disease and treatment information, distress as measured by the DT and problems as identified by the PC. For the current study the focus was on the number of referrals offered and the number accepted or declined. The type of services referred to was also examined. Results: Data were collected for 877 patients although missing data resulted in a final sample size of 853. Only data associated with the first DT of each patient are presented. 729 patients (86%) participated in distress screening. The distress threshold of 4 was reported by 50% of participants, highlighting the prevalence of distress requiring support. This 50% reported an average of 9 problems on the PC, many of which came from the physical domain, with 91% reporting at least 1 physical problem. Other problems reported were emotional (74% of the sample); practical (24%), family (14%) and spiritual (2%). Referral data, which was available for 614 people, indicated that over 60% (372) were offered at least one referral. Referral offer was significantly predicted by DT score, and number of problems reported. Acceptance was significantly related to total number of problems, treatment type, and type of referral; referral for physical treatment was most likely to be accepted (87%) whereas referral for emotional support was least likely (53%). Conclusion: Routine distress screening and problem identification are critical to triaging to supportive care services. In a tertiary care setting, not all people will be screened or will want to be screened; not all people will be referred to services; and not all people will accept referral. Nonetheless, problems are extensive with most survivors reporting experiencing several problems. Despite a focus on the physical, these problems extend to other domains, including the emotional, and it is important that services are available to support these needs.
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Teare, Sheldon, and Danielle Measday. "Pyrite Rehousing – Recent Case Studies at Two Australian Museums." Biodiversity Information Science and Standards 2 (June 13, 2018): e26343. http://dx.doi.org/10.3897/biss.2.26343.
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Two major collecting institutions in Australia, the Australian Museum (Sydney) and Museums Victoria (Melbourne), are currently undertaking large-scale anoxic rehousing projects in their collections to control conservation issues caused by pyrite oxidation. This paper will highlight the successes and challenges of the rehousing projects at both institutions, which have collaborated on developing strategies to mitigate loss to their collections. In 2017, Museums Victoria Conservation undertook a survey with an Oxybaby M+ Gas Analyser to assess the oxygen levels in all their existing anoxic microclimates before launching a program to replace failed microclimates and expand the number of specimens housed in anoxic storage. This project included a literature review of current conservation materials and techniques associated with anoxic storage, and informed the selection of the RP System oxygen scavenger and Escal Neo barrier film from Mitsubishi Gas Chemical Company as the best-practice products to use for this application. Conservation at the Australian Museum in Sydney was notified of wide-scale pyrite decay in the Palaeontology and Mineral collections. It was noted that many of the old high-barrier film enclosures, done more than ten years ago, were showing signs of failing. None of the Palaeontology specimens had ever been placed in microclimates. After consultation with Museums Victoria and Collection staff, a similar pathway used by Museums Victoria was adopted. Because of the scale of the rehousing project, standardized custom boxes were made, making the construction of hundreds of boxes easier. It is hoped that new products, like the tube-style Escal film, will extend the life of this rehousing project. Enclosures are being tested at the Australian Museum with a digital oxygen meter. Pyrite rehousing projects highlight the loss of Collection materials and data brought about by the inherent properties of some specimens. The steps undertaken to mitigate or reduce the levels of corrosion are linked to the preservation of both the specimens and the data kept with them (paper labels). These projects benefited from the collaboration of Natural Sciences conservators in Australia with Geosciences collections staff. Natural Science is a relatively recent specialization for the Australian conservation profession and it is important to build resources and capacity for conservators to care for these collections. This applied knowledge has already been passed on to other regions in Australia.
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Booth, Alison. "MILLENNIAL VICTORIA." Victorian Literature and Culture 29, no. 1 (March 2001): 159–70. http://dx.doi.org/10.1017/s1060150301291104.
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HAVING SURVIVED THE Y2K HYSTERIA, we may feel we have entered new corridors of one hundred and one thousand years. But it is only in 2001 that the punctilious and historical among us may at last observe a centennial, truly the final year of the past century and the hundredth anniversary of the death of Queen Victoria.1 The Jubilees in the last decades of Victoria’s life, and the ceremonies of international mourning that followed her death, might seem to have said goodbye to all that, but in many ways we are still under the sway of the great queen who lent her name to the age before “the American century.” Our own fin-de-siècle urges us to rediscover the many forms of Victoria that have “been hidden in plain view for a hundred years,” as Margaret Homans and Adrienne Munich put it in their co-edited collection of essays, Remaking Queen Victoria (1).2 While North American and British feminist studies have dwelt among Victorian ways since the 1970s — with implications that I will consider below — the queen herself has recently commanded critical attention that might seem, like so many features of Victoria’s public performance, out of proportion. Yet that excess, like our obeisance to the arbitrary power of the calendar, seems to be the very stuff of imagined community and ideological construction, and thus worth watching in action. In any case, when feminist literary critics such as Adrienne Munich, Margaret Homans, and Gail Turley Houston
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Parmentier, Marie-Agnès. "When David Met Victoria." Family Business Review 24, no. 3 (May 10, 2011): 217–32. http://dx.doi.org/10.1177/0894486511408415.
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This article seeks to understand how distinctive family brands are created. Recent studies in family business have focused on the benefits for a firm to be known as family owned or family controlled. Few studies have paid attention to the distinct meanings stakeholders associate with a given family or to how that family comes to have those associations in the eyes of external stakeholders. Based on a case study of one of the entertainment industry’s most successful family brands—The Beckhams—four practices conducive to building brand distinctiveness and brand visibility are identified.
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Whitehouse, Hilary L. W., and Sandra G. Taylor. "A Gender Inclusive Curriculum Model for Environmental Studies." Australian Journal of Environmental Education 12 (1996): 77–83. http://dx.doi.org/10.1017/s0814062600001609.
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AbstractThis paper presents a gender inclusive curriculum model for environmental studies at the senior secondary level. The curriculum model is based on three sources of information about gender and environmental studies: ecofeminist theory concerning Western constructions of the humanity–nature relation, socialist feminist critique of academic and professional practice in the environmental disciplines, and an analysis of syllabus documents produced for senior secondary environmental studies courses in South Australia and Victoria. The model induces recommendations concerning the representation of the concept ‘environment’ in the syllabus, the portrayal of women in the syllabus, and the pedagogic and assessment strategies promoted in the syllabus.
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Wheeler, Fiona, and Jennifer Laing. "Tourism as a Vehicle for Liveable Communities: Case studies from regional Victoria, Australia." Annals of Leisure Research 11, no. 1-2 (January 2008): 242–63. http://dx.doi.org/10.1080/11745398.2008.9686795.
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Hunt, Steven. "Getting Classics into Secondary Schools: Three Case Studies." Journal of Classics Teaching 19, no. 37 (2018): 64–70. http://dx.doi.org/10.1017/s2058631018000107.
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Despite the challenges which are involved, some secondary schools show determination to get Classics onto the timetable and into their curricular provision. The following three case studies draw on interviews with the people directly involved in doing so: the Principals and the teachers themselves. These experiences were captured at the time when they were getting Classics into their schools. The first is derived from an interview with a qualified specialist Classics teacher, ‘Rachel’, working in London. Latin already had a presence there from when the school had employed a part-time teacher; the remit was the development of a full Classics department. The second is based on interviews with the school head teacher and a non-specialist Modern Languages teacher ‘Yvonne’ who had been employed to start a Classics department from scratch in a school in the Midlands. The third is based on an interview with the Principal of an academy which had decided to introduce Latin not only into her own school with a new teacher ‘George’, but also into one that was not yet built. The respondents’ real names have, of course, been changed.
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Powell, Richard R. "Case studies of second‐career secondary student teachers." International Journal of Qualitative Studies in Education 7, no. 4 (October 1994): 351–66. http://dx.doi.org/10.1080/0951839940070405.
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Serena, M., and G. A. Williams. "Movements and cumulative range size of the platypus (Ornithorhynchus anatinus) inferred from mark–recapture studies." Australian Journal of Zoology 60, no. 5 (2012): 352. http://dx.doi.org/10.1071/zo12121.
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The extent of mammalian movements often varies with size, sex and/or reproductive status. Fyke nets were set along streams and rivers near Melbourne (southern Victoria) from the mid-1990s to 2007, and in the Wimmera River catchment (western Victoria) from 1997 to 2005, to assess how far platypus of different age and sex classes travelled between captures and over longer periods. The mean distance between consecutive captures of adults did not vary significantly as intervals increased from 1–3 months to >3 years, suggesting that most individuals occupied stable ranges. However, adult females travelled, on average, only 35% as far between captures as males in southern Victoria, and 29% as far in the Wimmera. Up to half of this difference may be explained by variation in size-related metabolic requirements. Immature males and females respectively moved 61% and 53% as far, on average, as their adult equivalents, although two young males dispersed >40 km. Adults incrementally occupied up to 13.9 km of channel in the case of a male (based on six captures over 67 months) and 4.4 km of channel in the case of a female (based on five captures over 127 months).
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Laing, Jennifer, and Warwick Frost. "Food, Wine … Heritage, Identity? Two Case Studies of Italian Diaspora Festivals in Regional Victoria." Tourism Analysis 18, no. 3 (August 9, 2013): 323–34. http://dx.doi.org/10.3727/108354213x13673398610817.
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Slick, Daniel J., Jing E. Tan, Esther Strauss, Catherine A. Mateer, Michael Harnadek, and Elisabeth M. S. Sherman. "Victoria Symptom Validity Test Scores of Patients with Profound Memory Impairment: NonLitigant Case Studies." Clinical Neuropsychologist 17, no. 3 (August 2003): 390–94. http://dx.doi.org/10.1076/clin.17.3.390.18090.
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Porter, Joanne E., Nareeda Miller, Anita Giannis, and Nicole Coombs. "Family Presence During Resuscitation (FPDR): Observational case studies of emergency personnel in Victoria, Australia." International Emergency Nursing 33 (July 2017): 37–42. http://dx.doi.org/10.1016/j.ienj.2016.12.002.
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Beed, Clive, and Patrick Moriarty. "How Convincing was the Economic Case for Restructuring Local Government in Victoria?" Urban Policy and Research 5, no. 3 (September 1987): 117–25. http://dx.doi.org/10.1080/08111148708551304.
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Steinberg, Reece Axl. "Case Studies, Cuts, and Critical Information Literacy." Journal of Contemporary Issues in Education 15, no. 1 (June 28, 2020): 51–64. http://dx.doi.org/10.20355/jcie29414.
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Post-secondary institutions are responding to cuts in government funding by prioritizing skills-building directly related to employment. Conservative governments ignore employers’ call for transferable skills in new graduates, and use funding cuts to pressure educational institutions’ focus. Librarians face the challenging task of offering instruction in both specific technical skills and transferable thinking skills in a limited time period. Critical information literacy is increasingly included as part of instruction in post-secondary libraries, in addition to technical use of library resources.
Case studies in library classes or workshops fit within required guidelines for career-focused learning and practical skills-building while providing opportunities for students to engage in analysis of information. Cases lend themselves well to progressive, learner-focused, and flexible modes of instruction. This paper includes practical examples of library instruction using case studies, and reasons to consider them a radical, relevant tool in post-secondary library teaching.
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Wilson, Philip G., Susan G. Killam, Lauren Griffiths, Laura C. Stazio, Rebecca B. Ellis, McKenzie Esta, and Amarachi N. Ukachu. "Post-secondary apprenticeships for youth: Follow-up case studies." Journal of Vocational Rehabilitation 50, no. 3 (May 20, 2019): 279–84. http://dx.doi.org/10.3233/jvr-191008.
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Muhlebach, Robyn. "Curriculum and Professional Development in Environmental Education: A Case Study." Australian Journal of Environmental Education 11 (1995): 49–58. http://dx.doi.org/10.1017/s0814062600002962.
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This particular case study looks at the problem of curriculum and professional development in environmental education at a small semi rural primary school in south western Victoria. In this paper the ‘study’ refers to the case study research at Elliminyt Primary School and the ‘project’ refers to a wider OECD-CERI ENSI project which included many other case studies other than the one described here.
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FINLAYSON, B. L., and S. O. BRIZGA. "The Oral Tradition, Environmental Change and River Basin Management: Case Studies from Queensland and Victoria." Australian Geographical Studies 33, no. 2 (October 1995): 180–92. http://dx.doi.org/10.1111/j.1467-8470.1995.tb00693.x.
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Weiler, Betty, and Xin Yu. "Case Studies of the Experiences of Chinese Visitors to Three Tourist Attractions in Victoria, Australia." Annals of Leisure Research 11, no. 1-2 (January 2008): 225–41. http://dx.doi.org/10.1080/11745398.2008.9686794.
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Young, Suzanne. "Outsourcing: two case studies from the Victorian public hospital sector." Australian Health Review 31, no. 1 (2007): 140. http://dx.doi.org/10.1071/ah070140.
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Outsourcing was one process of privatisation used in the Victorian public health sector in the 1990s. However it was used to varying degrees and across a variety of different services. This paper attempts to answer the questions: Why have managers outsourced? What have managers considered when they have decided to outsource? The research was carried out in a rural hospital and a metropolitan network in Victoria. The key findings highlight the factors that decision makers considered to be important and those that led to negative outcomes. Economic factors, such as frequency of exchange, length of relationships between the parties, and information availability, were often ignored. However, other factors such as outcome measurability, technology, risk, labour market characteristics and goal conflict, and political factors such as relative power of management over labour were often perceived as important in the decision-making process. Negative outcomes from outsourcing were due to the short length of relationships and accompanying difficulties with trust, commitment and loyalty; poor quality; and excessive monitoring and the measurement of outcomes.
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Fiederlein, Suzanne L. "The 1994 Elections in Mexico: The Case of Chiapas." Mexican Studies/Estudios Mexicanos 12, no. 1 (January 1, 1996): 107–30. http://dx.doi.org/10.2307/1052080.
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Este artículo examina las elecciones de 1994 en Chiapas, así como los acontecimientos previos y sus resultados y ramificaciones. El levantamiento zapatista tuvo un impacto profundo en el proceso electoral en Chiapas, así como sobre el movimiento nacional de democratización en México. Mientras que las irregularidades electorales ocurridas por todo el país no fueron vistas como lo suficientemente importantes para desafiar la victoria del partido en el poder en cuanto a la elección de presidente, los resultados oficiales en Chiapas, en particular sobre la elección de gobernador, no se consideraron limpios. Desde las elecciones, los zapatistas y una sociedad civil más vigorosa han continuado la presión sobre el gobierno nacional para implementar una reforma electoral y para resolver cuestiones más amplias, como justicia económica, democratización y responsabilidad gubernamental.
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Willey, Stephen. "Planning Appeals: Are Third Party Rights Legitimate? The Case Study of Victoria, Australia." Urban Policy and Research 24, no. 3 (September 2006): 369–89. http://dx.doi.org/10.1080/08111140600877032.
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Marks, Gary N., and John Cresswell. "State Differences in Achievement among Secondary School Students in Australia." Australian Journal of Education 49, no. 2 (August 2005): 141–51. http://dx.doi.org/10.1177/000494410504900203.
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A number of recent national studies of student achievement in secondary school have reported differences between the Australian states and territories. State differences are often viewed as insubstantial or as simply reflecting sociodemographic factors, or differences between the states in the grades or ages of the students sampled. In this article, we show that state differences are larger than generally assumed and cannot be attributed to socioeconomic and demographic factors. Generally, student achievement in reading, mathematics and science are higher in New South Wales than the other states, once demographic and grade differences are taken into account. Of concern, is the increased likelihood that students from Queensland, Victoria and Tasmania have in only reaching the lowest OECD proficiency level in reading. We conclude that state differences are meaningful and do have policy implications.
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Yoon, Yeohyun, and Kyoung Cheon Cha. "A Qualitative Review of Cruise Service Quality: Case Studies from Asia." Sustainability 12, no. 19 (September 30, 2020): 8073. http://dx.doi.org/10.3390/su12198073.
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Although the cruise sector is considered an ‘unreplaceable’ form of tourism, with the cruise industry recording steady growth over the years, there is a lack of research and analysis on cruise ships themselves. Accordingly, this study sought to determine whether service quality differences among ships operating in the Asian market could suggest broader implications for the sustainability of the cruise industry. We chose the SERVQUAL framework for the analysis; we also employed the multiple case study method and topic synthesis to compare the service quality of three ships. Of the ships investigated—the Costa Victoria, Diamond Princess, and Superstar Virgo—the Diamond Princess had the highest service quality. Based on the results, we outlined suggestions for improving the quality of cruise services, including introducing the latest large ships and high-tech facilities, complying with the departure and arrival times of sailing schedules, improving the ratio of crew members per passenger, establishing a cruise personnel training system, and expanding membership program operations.
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KLICK, B., G. M. LEUNG, and B. J. COWLING. "Optimal design of studies of influenza transmission in households. I: Case-ascertained studies." Epidemiology and Infection 140, no. 1 (March 22, 2011): 106–14. http://dx.doi.org/10.1017/s0950268811000392.
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SUMMARYCase-ascertained household transmission studies, in which households including an ‘index case’ are recruited and followed up, are invaluable to understanding the epidemiology of influenza. We used a simulation approach parameterized with data from household transmission studies to evaluate alternative study designs. We compared studies that relied on self-reported illness in household contacts vs. studies that used home visits to collect swab specimens for virological confirmation of secondary infections, allowing for the trade-off between sample size vs. intensity of follow-up given a fixed budget. For studies estimating the secondary attack proportion, 2–3 follow-up visits with specimens collected from all members regardless of illness were optimal. However, for studies comparing secondary attack proportions between two or more groups, such as controlled intervention studies, designs with reactive home visits following illness reports in contacts were most powerful, while a design with one home visit optimally timed also performed well.
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Aggarwal, R., I. E. Lundberg, Y. W. Song, A. Shaibani, V. P. Werth, and M. A. Maldonado. "POS0839 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL TO EVALUATE EFFICACY AND SAFETY OF SC ABATACEPT IN ADULTS WITH ACTIVE IDIOPATHIC INFLAMMATORY MYOPATHY." Annals of the Rheumatic Diseases 81, Suppl 1 (May 23, 2022): 711.2–711. http://dx.doi.org/10.1136/annrheumdis-2022-eular.7.
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BackgroundLimited therapies are available for patients with idiopathic inflammatory myopathy (IIM), a heterogenous group of chronic, systemic, autoimmune inflammatory diseases characterized by progressive muscle weakness and/or distinct skin rashes.1 Abatacept, a selective co-stimulation modulator, may be a useful treatment option.2ObjectivesTo evaluate efficacy, safety, and tolerability of abatacept + standard of care (SOC) in patients with IIM compared with SOC alone (placebo).MethodsA 24-week, randomized, double-blind, placebo-controlled phase 3 trial of SC abatacept (125 mg weekly) + SOC (corticosteroids and immunosuppressants alone or combined; NCT02971683) in patients with active, treatment-refractory IIM (Manual Muscle Testing-8 [MMT-8] ≤ 135) was performed. Primary endpoint was proportion of patients meeting International Myositis Assessment and Clinical Studies definition of improvement (IMACS DOI) at week 24. Change from baseline in myositis Functional Index-2 (FI-2), HAQ-DI, Myositis Disease Activity Assessment Tool (MDAAT), and Myositis Response Criteria (MRC) were secondary endpoints with safety. Post hoc analyses by disease subtype were performed.ResultsOverall, 148 patients were randomized (75 abatacept; 73 placebo); IIM subtypes were dermatomyositis (DM; 53.3% vs 57.5%), polymyositis (PM; 25.3% vs 34.2%), and autoimmune necrotizing myopathy (ANM; 21.3% vs 8.2%). Mean baseline MMT-8 and HAQ-DI scores were 112.7 and 1.5, respectively. Approximately 90% of patients completed week 24. Week 24 IMACS DOI rates were abatacept 56.0% vs placebo 42.5% (adjusted odds ratio, 1.8 [95% CI, 0.9–3.5]; P = 0.083). Pre-specified IMACS DOI analysis showed no differences for patients with DM but notable benefit for those with non-DM subtypes, PM and ANM (Table 1). Secondary endpoints showed similar differences (Table 1). MRC at day 169 by category is shown in Figure 1. Proportion of AEs (69.3% and 75.3%) and serious AEs (5.3% and 5.5%) were similar in the abatacept and placebo arms.Table 1.Primary and secondary (mean change from baseline at week 24) endpointsOutcomeIIMAbataceptPlaceboNominal P value (abatacept vs placebo) or adjusted mean difference from placebo (95% CI)IMACS DOI,a n/N (%)All42/75 (56.0)31/73 (42.5)P = 0.083DM22/40 (55.0)21/42 (50.0)P = 0.679Non-DM20/35 (57.1)10/31 (32.3)P = 0.040FI-2All4.1 (1.3)1.2 (1.4)2.9 (0 to 5.8)DM2.3 (1.6)0.3 (1.4)1.9 (−2.3 to 6.2)Non-DM3.2 (1.4)−0.6 (1.5)3.7 (−0.3 to 7.8)HAQ-DIAll−0.31 (0.07)0.20 (0.07)−0.12 (−0.28 to 0.04)DM−0.31 (0.08)−0.19 (0.07)−0.11 (−0.32 to 0.10)Non-DM−0.25 (0.09)−0.07 (0.09)−0.18 (−0.44 to 0.07)MDAAT, Extramuscular Global Activity, (95% CI)bAll−1.56 (−1.96 to −1.16)−1.40 (−1.81 to −0.99)−0.16 (−0.63 to 0.30)DM−1.90 (−2.43 to −1.37)−1.85 (−2.35 to 1.36)−0.05 (−0.77 to 0.68)Non-DM−1.09 (−1.46 to −0.72)−0.85 (−1.27 to −0.43)−0.24 (−0.80 to 0.32)MMT-8All12.9 (1.9)11.0 (2.0)1.8 (−2.7 to 6.4)DM14.4 (2.2)14.0 (2.2)0.4 (−5.7 to 6.4)Non-DM12.1 (2.5)7.8 (2.7)4.3 (−3.0 to 11.7)Physician Global AssessmentbAll−2.89 (0.30)−2.69 (0.30)−0.20 (−0.92 to 0.52)DM−2.78 (0.29)−2.43 (0.28)−0.35 (−1.15 to 0.46)Non-DM−2.35 (0.43)−2.21 (0.48)−0.14 (−1.43 to 1.15)Patient Global AssessmentbAll−1.4 (0.31)−0.98 (0.32)−0.38 (−1.11 to 0.35)DM−1.4 (0.33)−1.4 (0.31)−0.00 (−0.91 to 0.90)Non-DM−1.2 (0.41)−0.3 (0.44)−0.93 (−2.14 to 0.29)Data are adjusted mean change from baseline score (SE) unless stated.aDefined as improvement of ≥ 20% in 3 IMACS core measures, worsening by ≥ 25% in ≤ 2 IMACS core measure scores, and a reduction of < 25% in MMT-8; b100 mm visual analog scale.ConclusionIn this double-blind trial of SC abatacept vs placebo, abatacept failed to meet primary or secondary endpoints. Post hoc analyses suggest a treatment benefit in patients with PM and ANM (not DM) when treated with abatacept. Abatacept use was well tolerated.References[1]Dalakas MC, Hohlfeld R. Lancet 2003;362:971–82.[2]Tjärnlund A, et al. Ann Rheum Dis 2018;77:55–62.AcknowledgementsThis study was sponsored by Bristol Myers Squibb. Medical writing and editorial assistance were provided by Fiona Boswell, PhD, of Caudex and were funded by Bristol Myers Squibb. Study execution was by Sandra Overfield and Robin Scully.Disclosure of InterestsRohit Aggarwal Consultant of: AbbVie, Alexion, Argenx, AstraZeneca, Boehringer Ingelheim, Bristol Myers Squibb, Corbus, CSL Behring, EMD Serono, Janssen, Jubilant, Kezar, Kyverna, Mallinckrodt, Octapharma, Orphazyme, Pfizer, Q32, Roivant (personal fees), Grant/research support from: Bristol Myers Squibb, EMD Serono, Genentech, Mallinckrodt, Pfizer, Q32, Ingrid E. Lundberg Shareholder of: Novartis, Roche, Consultant of: Argenx, AstraZeneca, Corbus, EMD Serono, Janssen, Kezar, Octapharma, Orphazyme (personal fees), Grant/research support from: Bristol Myers Squibb, Yeong Wook Song: None declared, Aziz Shaibani: None declared, Victoria P Werth Consultant of: AbbVie, Akari, Amgen, Argenx, AstraZeneca, Bayer, Beacon Bioscience, Biogen, Bristol Myers Squibb, Celgene, Corcept, Crisalis, CSL Behring, Cugene, EMD Serono, Genentech, Gilead, GlaxoSmithKline, Horizon, Idera, Incyte, Janssen, Kezar, Kwoya Kirin, Lilly, Medimmune, Medscape, Merck, Nektar, Octapharma, Pfizer, Principia, Regeneron, Resolve, Rome Pharmaceuticals, Sanofi, UCB, Viela Bio, Grant/research support from: Amgen, Argenx, AstraZeneca, Biogen, Bristol Myers Squibb, Celgene, Corbus Pharmaceuticals, CSL Behring, Genentech, Gilead, Janssen, Pfizer, q32 Bio, Regeneron, Syntimmune, Ventus, Viela, Michael A Maldonado Employee of: Bristol Myers Squibb
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Nanayakkara, Janandani, Claire Margerison, and Anthony Worsley. "Food professionals’ opinions of the Food Studies curriculum in Australia." British Food Journal 119, no. 12 (December 4, 2017): 2945–58. http://dx.doi.org/10.1108/bfj-02-2017-0112.
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Purpose The purpose of this paper is to investigate the food system professionals’ opinions of a new senior secondary school food literacy curriculum named Victorian Certificate of Education Food Studies in Victoria, Australia. Design/methodology/approach A purposive sample of 34 food system professionals from different sub-sectors within the Australian food system was interviewed individually in late 2015 and early 2016. Interviews were analysed using the template analysis technique. Findings Most participants appreciated the extensive coverage of food literacy aspects in this new curriculum. However, many suggested amendments to the curriculum including pay less emphasis on food history-related topics and pay more focus on primary food production, nutrition awareness and promotion, and food security, food sovereignty, social justice, and food politics. Practical implications A well-structured, comprehensive secondary school food literacy curriculum could play a crucial role in providing food literacy education for adolescents. This will help them to establish healthy food patterns and become responsible food citizens. The findings of this study can be used to modify the new curriculum to make it a more comprehensive, logical, and feasible curriculum. Moreover, these findings could be used to inform the design of new secondary school food literacy curricula in Australia and other countries. Originality/value The exploration of perspectives of professionals from a broad range of food- and nutrition-related areas about school food literacy education makes this study unique. This study highlights the importance of food professionals’ opinions in secondary school food-related curricula development.
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Meyer, Britta S., Adrian Indermaur, Xenia Ehrensperger, Bernd Egger, Gaspard Banyankimbona, Jos Snoeks, and Walter Salzburger. "Back to Tanganyika: a case of recent trans-species-flock dispersal in East African haplochromine cichlid fishes." Royal Society Open Science 2, no. 3 (March 2015): 140498. http://dx.doi.org/10.1098/rsos.140498.
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The species flocks of cichlid fishes in the East African Great Lakes are the largest vertebrate adaptive radiations in the world and illustrious textbook examples of convergent evolution between independent species assemblages. Although recent studies suggest some degrees of genetic exchange between riverine taxa and the lake faunas, not a single cichlid species is known from Lakes Tanganyika, Malawi and Victoria that is derived from the radiation associated with another of these lakes. Here, we report the discovery of a haplochromine cichlid species in Lake Tanganyika, which belongs genetically to the species flock of haplochromines of the Lake Victoria region. The new species colonized Lake Tanganyika only recently, suggesting that faunal exchange across watersheds and, hence, between isolated ichthyofaunas, is more common than previously thought.
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Brownstein, Naomi C., Jianwen Cai, Shad Smith, Luda Diatchenko, Gary D. Slade, and Eric Bair. "Modeling Secondary Phenotypes Conditional on Genotypes in Case–Control Studies." Stats 5, no. 1 (February 22, 2022): 203–14. http://dx.doi.org/10.3390/stats5010014.
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Traditional case–control genetic association studies examine relationships between case–control status and one or more covariates. It is becoming increasingly common to study secondary phenotypes and their association with the original covariates. The Orofacial Pain: Prospective Evaluation and Risk Assessment (OPPERA) project, a study of temporomandibular disorders (TMD), motivates this work. Numerous measures of interest are collected at enrollment, such as the number of comorbid pain conditions from which a participant suffers. Examining the potential genetic basis of these measures is of secondary interest. Assessing these associations is statistically challenging, as participants do not form a random sample from the population of interest. Standard methods may be biased and lack coverage and power. We propose a general method for the analysis of arbitrary phenotypes utilizing inverse probability weighting and bootstrapping for standard error estimation. The method may be applied to the complicated association tests used in next-generation sequencing studies, such as analyses of haplotypes with ambiguous phase. Simulation studies show that our method performs as well as competing methods when they are applicable and yield promising results for outcome types, such as time-to-event, to which other methods may not apply. The method is applied to the OPPERA baseline case–control genetic study.
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Ma, Yanyuan, and Raymond J. Carroll. "Semiparametric estimation in the secondary analysis of case-control studies." Journal of the Royal Statistical Society: Series B (Statistical Methodology) 78, no. 1 (February 15, 2015): 127–51. http://dx.doi.org/10.1111/rssb.12107.
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Bowes, Joanne, Duncan Armstrong, Michael Rolf, and Jean-Pierre Valentin. "Secondary pharmacology: Case studies of integration with safety pharmacology data." Journal of Pharmacological and Toxicological Methods 64, no. 1 (July 2011): e17-e18. http://dx.doi.org/10.1016/j.vascn.2011.03.064.
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Miettinen, Olli S. "Subject selection in case-referent studies with a secondary base." Journal of Chronic Diseases 40, no. 2 (January 1987): 186–87. http://dx.doi.org/10.1016/0021-9681(87)90072-5.
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Ghosh, Arpita, Fred A. Wright, and Fei Zou. "Unified Analysis of Secondary Traits in Case–Control Association Studies." Journal of the American Statistical Association 108, no. 502 (June 2013): 566–76. http://dx.doi.org/10.1080/01621459.2013.793121.
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Lim, Vivien. "A practical approach to secondary osteoporosis – Case studies in Asia." Osteoporosis and Sarcopenia 2, no. 3 (September 2016): 134–39. http://dx.doi.org/10.1016/j.afos.2016.07.003.
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Chávez, Karma R. "Spatializing Gender Performativity: Ecstasy and Possibilities for Livable Life in the Tragic Case of Victoria Arellano." Women's Studies in Communication 33, no. 1 (May 4, 2010): 1–15. http://dx.doi.org/10.1080/07491401003669729.
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Loreman, Tim, Joanne Deppeler, David Harvey, and Glenn Rowley. "The Implications of Inclusion through Curriculum Modification for Secondary School Teacher Training in Victoria, Australia." International Journal of Diversity in Organizations, Communities, and Nations: Annual Review 4, no. 1 (2006): 0. http://dx.doi.org/10.18848/1447-9532/cgp/v04/38970.
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Fawns, Rod, and David Nance. "Teacher Knowledge, Education Studies and Advanced Skills Credentials." Australian Journal of Education 37, no. 3 (November 1993): 248–58. http://dx.doi.org/10.1177/000494419303700303.
Full textAbstract:
It is argued that appraisal of advanced skills in teaching should be based on the pedagogical content knowledge which good teachers, in biology for instance, could be expected to possess and which a well-trained biologist would not. Public acceptance of this claim is the key element in any argued case for a career restructuring which rewards the development of teaching expertise in schools and universities. Several initial schemes employed in Victoria for appraisal of Advanced Skills Teacher 1 are critically examined. An alternative to the competency-based approaches is presented, founded on research into the development of practical reasoning of teachers.