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Journal articles on the topic "Scar60"

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Yu, Bowen, Chen Cheng, Yichun Wu, Luqiang Guo, Dandan Kong, Ze Zhang, Yuanyuan Wang, Enlin Zheng, Yingbin Liu, and Yongning He. "Interactions of ferritin with scavenger receptor class A members." Journal of Biological Chemistry 295, no. 46 (September 9, 2020): 15727–41. http://dx.doi.org/10.1074/jbc.ra120.014690.

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Scavenger receptors are a superfamily of membrane-bound receptors that recognize both self and nonself targets. Scavenger receptor class A (SR-A) has five known members (SCARA1 to -5 or SR-A1 to -A5), which are type II transmembrane proteins that form homotrimers on the cell surface. SR-A members recognize various ligands and are involved in multiple biological pathways. Among them, SCARA5 can function as a ferritin receptor; however, the interaction between SCARA5 and ferritin has not been fully characterized. Here, we determine the crystal structures of the C-terminal scavenger receptor cysteine-rich (SRCR) domain of both human and mouse SCARA5 at 1.7 and 2.5 Å resolution, respectively, revealing three Ca2+-binding sites on the surface. Using biochemical assays, we show that the SRCR domain of SCARA5 recognizes ferritin in a Ca2+-dependent manner, and both L- and H-ferritin can be recognized by SCARA5 through the SRCR domain. Furthermore, the potential binding region of SCARA5 on the surface of ferritin is explored by mutagenesis studies. We also examine the interactions of ferritin with other SR-A members and find that SCARA1 (SR-A1, CD204) and MARCO (SR-A2, SCARA2), which are highly expressed on macrophages, also interact with ferritin. By contrast, SCARA3 and SCARA4, the two SR-A members without the SRCR domain, have no detectable binding with ferritin. Overall, these results provide a mechanistic view regarding the interactions between the SR-A members and ferritin that may help to understand the regulation of ferritin homeostasis by scavenger receptors.
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Poynter, S. J., A. L. Monjo, and S. J. DeWitte-Orr. "Identification of three class A scavenger receptors from rainbow trout (Oncorhynchus mykiss): SCARA3, SCARA4, and SCARA5." Fish & Shellfish Immunology 76 (May 2018): 121–25. http://dx.doi.org/10.1016/j.fsi.2018.02.029.

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Burgess, Adam. "Scared to death. From BSE to global warming: Why scares are costing us the earth." Health, Risk & Society 13, no. 7-8 (October 2011): 711–12. http://dx.doi.org/10.1080/13698570902796681.

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He, Jianyu, Huihui Liu, and Changwen Wu. "Identification of SCARA3, SCARA5 and MARCO of class A scavenger receptor-like family in Pseudosciaena crocea." Fish & Shellfish Immunology 41, no. 2 (December 2014): 238–49. http://dx.doi.org/10.1016/j.fsi.2014.07.037.

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Sandman, Peter M., and JoAnn M. Valenti. "Scared stiff — or scared into action." Bulletin of the Atomic Scientists 42, no. 1 (January 1986): 12–16. http://dx.doi.org/10.1080/00963402.1986.11459304.

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Majeed, Mustafa Usama Abdul. "The Use of MEBO Scar Ointment in the Treatment and Prevention of Post-Operative Wound Scars." International Journal of Pharma Research and Health Sciences 4, no. 3 (2016): 1171–78. http://dx.doi.org/10.21276/ijprhs.2016.03.05.

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Sherman, D. J., and K. F. Nordstrom. "Beach scarps." Zeitschrift für Geomorphologie 29, no. 2 (August 7, 1985): 139–52. http://dx.doi.org/10.1127/zfg/29/1985/139.

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Mertens, Joan R. "Timeas's Scarab." Metropolitan Museum Journal 24 (January 1989): 53–56. http://dx.doi.org/10.2307/1512867.

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Messerli, Douglas. "Scared Cows." boundary 2 14, no. 1/2 (1985): 94. http://dx.doi.org/10.2307/303506.

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Newton, Richard. "Scared Sheetless." Journal of Religion and Violence 7, no. 3 (2019): 303–22. http://dx.doi.org/10.5840/jrv202031172.

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The ideology of white supremacy is alive and well in the U.S. This paper argues that those attempting to understand how white supremacy works should delve into recent justifications of anti-black violence rather than simply waiting to spot the white sheets of the Ku Klux Klan. Doing so requires scholars to disabuse themselves of taking for granted the descriptions of what may be characterized as a U.S. Christian-White imaginary and to observe the dynamic, discursive shifts that Jean-Franc̜ois Bayart calls “operational acts of identification.” Drawing on incidents from antebellum slavery to the Black Lives Matter era and beyond, it is argued that white people have long been able to justify anti-black violence by appealing to a biblicist “Negrophobia,” wherein black people are rendered as frightening, even demonic creatures that must be stopped for the good of God’s kingdom. This paper presents a critical history of violence in America that is representative of a devastatingly effective strategy that continues to fortify the functional primacy of whiteness despite popular rejections of racism.
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Dissertations / Theses on the topic "Scar60"

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Montgomery, Jade. "Building a Better Scar: Re-engineering Extracellular Matrix Structure in Dermal Scars." Diss., Virginia Tech, 2020. http://hdl.handle.net/10919/104233.

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Introduction Cutaneous scars represent a common surgical complication, yet no effective drug therapy for scar treatment currently exists despite huge patient and physician demand. A connexin 43 (Cx43) carboxyl terminus (CT) mimetic peptide, alpha Connexin Carboxy-Terminus 1 (αCT1), has demonstrated efficacy in improving long-term scar appearance in pre-clinical and clinical trials. However, current understanding of the mechanism-of-action by which αCT1 improves long-term scar appearance with early intervention treatment is not well understood. Methods In vivo: Scar biopsies from 1) human, 2) Sprague-Dawley rat, and 3) IAF Hairless guinea pig trials of αCT1 were examined for collagen matrix structure at 4 weeks (all models), and 2 and 6 weeks (rat and guinea pig models only). Collagen matrix variables examined included local disorganization of the fibers, a variable that is higher in unwounded skin compared to scar tissue, and density of the fibers, which is higher in scar tissue but can also be used as an early temporal marker of the rate of healing. In vitro: Primary murine dermal fibroblasts were isolated from the whole dermis of 3-4 week old transgenic mice expressing collagen 1(α2) GFP-tpz. Cells were sorted for expression via FACS and plated on prealigned collagen substrate for 7 days under conditions favorable to generating extracellular matrix. Results All in vivo scar biopsies demonstrated some level of altered collagen matrix structure with αCT1 treatment. Treated scars had higher local disorganization of the collagen fibers within the wound, and an increase in collagen matrix density compared to control at certain earlier timepoints that tended to decrease or disappear at later timepoints. The IAF Hairless guinea pig, a novel splinted wound healing model presented herein, was found to closely replicate the human dermal collagen profile and changes in collagen profile spurred by αCT1, significantly outperforming the traditional rat model. Primary dermal murine fibroblasts treated in vitro with αCT1 significantly increased synthesis of procollagen 1, the precursor of collagen 1 necessary for constructing the extracellular matrix, suggesting that at least part of the reason for higher collagen density at early in vivo timepoints is due to increased collagen synthesis by fibroblasts. Conclusion αCT1 treatment in the early stages of wound healing prompts individual fibroblasts to increase their output of collagen and create a more disorganized early collagen matrix. These early changes potentially spur the long-term scar appearance improvements seen in clinical trials, and provide a basis for future work to discover the cellular pathways to alter in order to improve wound healing and cutaneous scarring outcomes.
Doctor of Philosophy
Skin wounds frequently result in scars that can range from barely visible to enormous eyesores. Almost everyone will experience at least one skin wound in their lifetime leading to a scar that they wish were less visible, feeding the multi-billion dollar market for anti-scarring agents. However, many of the products on store shelves that claim to reduce scar appearance have not proven those claims. Most of the therapies that do have some degree of scientific evidence to support their claims are difficult to use properly, such as silicone sheeting, and often result in only minor improvements to scar appearance. Alpha Connexin Carboxy-Terminus 1 (αCT1), marketed in clinical trials as Granexin® gel, is a protein-based therapy that works on the cellular level to fundamentally alter the skin's initial reaction to wounding and improving long-term scar appearance. This dissertation explores the link between cellular processes altered by αCT1 and long-term clinical improvements in scar appearance by studying both the extracellular matrix present in the scar in human and animal models and the creation of that extracellular matrix by dermal fibroblasts. In both human and animal models, topical application of αCT1 had no effect on skin surface appearance at early timepoints of 2-6 weeks, correlating with previous research that found scar appearance only improved at 3+ months post-injury. However, deep within the newly constructed tissue of the scar, these studies show the collagen organizational structure of αCT1-treated scars is more similar to unwounded skin and slightly more dense at early timepoints, suggesting αCT1 marginally improved the speed of healing. These findings in humans and animals were also verified in part in cell culture experiments that found dermal fibroblasts increased collagen output in response to αCT1 treatment. A novel wound healing model in the hairless guinea pig, superior at replicating human skin than established models like the rat, is also presented and shown to have effects strongly similar to the human with αCT1 treatment. These results provide a fundamental insight into the mode-of-action by which αCT1 may improve long term scar appearance and identifies early collagen structure as a target for future therapeutics to modify, as well as a new animal model in which to test them.
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Medeiros, Nathalia Maira Cabral de. "An?lise filogen?tica e funcional de dois genes de reparo hom?logos a AP endonuclease em cana-de-a??car: ScARP1 e ScARP3." Universidade Federal do Rio Grande do Norte, 2014. http://repositorio.ufrn.br:8080/jspui/handle/123456789/12627.

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Made available in DSpace on 2014-12-17T14:03:44Z (GMT). No. of bitstreams: 1 NathaliaMCM_DISSERT.pdf: 2544480 bytes, checksum: eab320fea2fc6e6b04c8d45099041a93 (MD5) Previous issue date: 2014-03-21
Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior
The genome of all organisms constantly suffers the influence of mutagenic factors from endogenous and/or exogenous origin, which may result in damage for the genome. In order to keep the genome integrity there are different DNA repair pathway to detect and correct these lesions. In relation to the plants as being sessile organisms, they are exposed to this damage frequently. The Base Excision DNA Repair (BER) is responsible to detect and repair oxidative lesions. Previous work in sugarcane identified two sequences that were homologous to Arabidopsis thaliana: ScARP1 ScARP3. These two sequences were homologous to AP endonuclease from BER pathway. Then, the aim of this work was to characterize these two sequence using different approaches: phylogenetic analysis, in silico protein organelle localization and by Nicotiana tabacum transgenic plants with overexpression cassette. The in silico data obtained showed a duplication of this sequence in sugarcane and Poaceae probably by a WGD event. Furthermore, in silico analysis showed a new localization in nuclei for ScARP1 protein. The data obtained with transgenic plants showed a change in development and morphology. Transgenic plants had slow development when compared to plants not transformed. Then, these results allowed us to understand better the potential role of this sequence in sugarcane and in plants in general. More work is important to be done in order to confirm the protein localization and protein characterization for ScARP1 and ScARP3
O genoma de todos os organismos sofre constantemente a influ?ncia de fatores mutag?nicos que podem ser de origem end?gena e/ou ex?gena, estes podem resultar em danos ao material gen?tico. Se esses danos n?o forem corrigidos pode levar ao aparecimento de muta??es. As plantas por serem organismos sesseis est?o continuamente expostas a estes fatores. Considerando isto, os organismos (animais e vegetais) possuem diferentes vias de reparo de DNA para manter a integridade do material gen?tico. Dentro destas vias, h? a via de Reparo por Excis?o de Bases (BER) que ? composta por diferentes enzimas, e dentro dessa via h? a enzima AP endonuclease que ? alvo deste estudo. Trabalhos anteriores em cana-de-a??car identificaram duas sequ?ncias de cDNA hom?logas a esta prote?na que foram denominadas ScARP1 e ScARP3. Com isso, o objetivo deste trabalho foi caracterizar estas duas sequ?ncias por meio de an?lises filogen?ticas utilizando sequ?ncias presentes dentro do reino Plantae, e de an?lises estruturais dos genes de AP endonuclease por an?lise in silico e por plantas transg?nicas contendo cassetes de super-express?o. Al?m disso, foi realizado transforma??es e a obten??o plantas transg?nicas de Nicotiana tabacum contendo cassetes de super-express?o em orienta??o anti-senso. Foi tamb?m analisado a rela??o filogen?tica de genes DNA ligase I presentes no organismo vegetal de estudo. Os resultados obtidos permitiram verificar que as sequ?ncias ScARP1 e ScARP3 correspondem a uma duplica??o, provavelmente devido a um processo de duplica??o do genoma como um todo (WGD) que deve ter ocorrido no grupo das gram?neas (Poaceae). Refor?ando estes dados, foi verificado um poss?vel direcionamento da prote?na para organelas diferentes, sendo que a ScARP1 pode ser encontrada no n?cleo e a ScARP3 em mitocondrias e/ou cloroplasto. Com rela??o as plantas transg?nicas contendo o cassete em orienta??o anti-senso foi observado que estas apresentaram crescimento lento quando comparado com a planta selvagem (n?o transformada). Al?m disso, seu fen?tipo abrange altera??es morfol?gicas no crescimento foliar, baixa estatura e diminui??o na produ??o de sementes. Entretanto, ainda se faz necess?rio a obten??o da linhagem homozigota para aprofundar essas observa??es. Desta forma, estes resultados permitem compreender um pouco melhor do poss?vel papel da enzima AP endonuclease em cana-de-a??car e em plantas
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Fisher, Andrea Christina. "Ablative Fractional Resurfacing for Burn Scars & the Impact on Adult Reconstructive Burn Surgery: Exploring the Effects of a Novel Treatment Paradigm." Thesis, The University of Sydney, 2021. https://hdl.handle.net/2123/26320.

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Burn scars are a major challenge in modern burn surgery. Severe scars often remain and can significantly diminish quality of life by causing disfigurement, pain, itchiness, contractures limiting the range of motion and functions of the body and joints. Ablative fractional CO2 laser (AFL-CO2) resurfacing has become a promising treatment modality for severe burn scars. The aim of this thesis was to analyse the efficacy and safety of AFL-CO2, whilst simultaneously aspiring to find explanations as to why this treatment modality has led to an overall different understanding of burn scar remodelling and why a simple approach can treat the underlying problem much more efficiently than conventional reconstructive burn surgery. A review of burn scars, traditional burn scar therapies, and an overview of light-based therapies for burn scars is provided. Subsequently, the creation of an extensive prospective database of every burn patient who was treated at Concord with AFL-CO2 laser as well as the methodologies of the following studies is described. The first study includes an analysis of the effectiveness and safety of AFL-CO2 laser for burn scars. The second project explores the effects of various laser penetration depths to establish guidance on new treatment settings. The third project includes an analysis of the effect of AFL-CO2 on conventional reconstructive procedures, hospital admission patterns, and length of stay. The fourth study illustrates the prophylactic potential of AFL-CO2 in the acute management of burn injuries. During the study period, the thorough, repetitive, and systematic clinical assessment of each burn scar over several years allowed for an improved understanding of burn scar development. This has in turn led to optimal treatment algorithms to be defined which are presented in this thesis as a conclusion of the previously listed projects. Overall, it has become clear that AFL-CO2 has allowed us to redefine the reconstructive approach to burn scars.
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Hirson, Denis. "White Scars." Thesis, University of East Anglia, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.410222.

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Dingwell, Christopher L. "The scars." The Ohio State University, 1993. http://rave.ohiolink.edu/etdc/view?acc_num=osu1316542218.

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Boscariol, Alice <1998&gt. "Tiziano Scarpa e la logocorporaleità." Master's Degree Thesis, Università Ca' Foscari Venezia, 2022. http://hdl.handle.net/10579/21089.

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Millin-Chalabi, Gail Rebecca. "Radar multi-temporal and multi-sensor approach to characterise peat moorland burn scars and assess burn scar persistence in the landscape." Thesis, University of Manchester, 2016. https://www.research.manchester.ac.uk/portal/en/theses/radar-multitemporal-and-multisensor-approach-to-characterise-peat-moorland-burn-scars-and-assess-burn-scar-persistence-in-the-landscape(36288daf-4a05-46e8-9e29-f67c62584fc5).html.

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Peat moorlands represent a nationally significant carbon store. Wildfires in peat moorlands release CO2 into the atmosphere, reducing the carbon store and burn into the seed bank preventing vegetation recovery. Burned areas of bare peat remain, known as ‘burn scars’ which are eroded by freeze thaw and desiccation, then weathered by precipitation and wind to cause discolouration of the water supply. A technique for the systematic monitoring of peat moorland burn scars is essential for informing land management and moorland restoration. Satellite data enables peat moorland burn scars to be monitored at the landscape scale for operational services e.g. European Forest Fire Information System (EFFIS). However, in the UK cloud is highly problematic for optical satellites and thermal data provides only a short window of opportunity for active fire detection. This thesis provides a unique line of enquiry by exploring the potential of Synthetic Aperture Radar (SAR) intensity and Interferometric Synthetic Aperture Radar (InSAR) coherence for burn scar characterisation and persistence, using a multi-temporal and multi-sensor approach for degraded peat moorland. The Peak District National Park (PDNP) was selected because it is a marginal moorland environment, which experiences high rates of peat erosion and will experience more wildfires, based on future projections of increased temperature, due to global warming. Initial SAR intensity results for the Bleaklow 2003 burn scar showed a clear post-fire increase of 7 dB for burned peat bog when acquired under wet conditions. Post-fire, dry − wet InSAR pairs were characterised by vegetation removal caused by combustion within the burn scar area, whereas wet − wet InSAR pairs characterised the burn scar, but also degraded peat moorland caused by previous wildfires blurring the new burn scar perimeter. Intensity differed significantly with slope for the PDNP 2003 wildfires, reducing the effectiveness of the technique for characterising burn scars on slopes facing away from the sensor, although these wildfires showed no significant difference on coherence for the inland bare ground class. When using coherence as a burn scar discriminator, this research found that it is essential to acquire InSAR pairs immediately post-fire with B⊥ < 550 m. Using a combination of intensity and coherence data a multi-difference colour composite was produced and an ISODATA classification applied. Results were reclassified to produce a burned area map with an overall map accuracy of 94% and Kappa Coefficient of 0.69 covering the Bleaklow and Kinder 2003 burn scars. Burn scars < 6 km2 provided a persistently higher burned area intensity signal for up to six months after the wildfire but only 2 − 3 months for coherence. The smaller Edale burn scar (0.10 km2) was characterised by 2 − 3 dB greater intensity for the burned area over a year after the wildfire. The Edale 2008 case study showed that L-band PALSAR data is less sensitive to characterising peat moorland burn scars compared to C-band data. This study therefore strongly recommends C-band data for peat moorland burn scar characterisation and monitoring. Future research will explore the new C-band Sentinel-1 data which offers improved spatial resolution and repeat-pass time.
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Riechers, Sören [Verfasser]. "Scheduling with scarce resources / Sören Riechers." Paderborn : Universitätsbibliothek, 2017. http://d-nb.info/1145017339/34.

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Hillmer, Michael. "Pharmacotherapy of keloid scars." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0023/MQ50486.pdf.

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Montanari, Giorgio Satoru. "Riciclo degli scarti della fibra di carbonio." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2017.

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L’aumento dell’utilizzo della fibra di carbonio in vari settori industriali, grazie alle sue caratteristiche migliori rispetto ai materiali convenzionali, ha provocato un conseguente aumento del numero di scarti prodotti. Il riciclo di materiali compositi è diventato un tema molto importante ma è anche difficile a causa della loro complessa composizione (fibre, matrice e riempitivi), della reticolazione nelle resine termoindurenti e della combinazione di altri materiali. Al giorno d’oggi, la maggior parte degli scarti di fibra di carbonio sono mandati in discarica. Questa è una soluzione insoddisfacente dal punto di vista dell’impatto ambientale, legislativo, della gestione delle risorse e dell’eventuale opportunità economica legata al riciclo degli scarti. Trai i vari metodi di recupero disponibili, si è scelto di utilizzare la pirolisi ed una susseguente fase di post-ossidazione per rimuovere la matrice. Si è svolta una ottimizzazione dei tempi di residenza e delle temperature di questi due processi per ottenere fibre con le migliori superfici e caratteristiche meccaniche finali. Questo lavoro è stato realizzato presso la Lamborghini Automobili.
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Books on the topic "Scar60"

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S, Gomez Jaime, ed. Introduction to video production. Boston: Pearson/Allyn and Bacon, 2004.

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Scarfe, Gerald. Scarfe by Scarfe. London: H. Hamilton, 1986.

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ill, Watson Wendy, ed. Scared. Toronto: Bantam Books, 1988.

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Craig, Dodd, ed. Scarfe. London: Hamish Hamilton, 1986.

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Bingham, Jane. Scared. New York: Crabtree Pub. Co., 2008.

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D'Ammassa, Don. Scarab. Waterville, Me: Five Star, 2004.

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Scarfe, Gerald. Scarfe. London: BBC, 1986.

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Scarfe, Gerald. Scarfe. London: Hamish Hamilton, 1986.

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Booker, Christopher. Scared to death: From BSE to global warming : how scares are costing us the Earth. London: Continuum, 2007.

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Richard, North, ed. Scared to death: From BSE to global warming : how scares are costing us the Earth. London: Continuum, 2007.

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Book chapters on the topic "Scar60"

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Ilankovan, Velupillai, and Anna Sayan. "Management of Facial Scars." In Oral and Maxillofacial Surgery for the Clinician, 747–57. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-1346-6_36.

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AbstractScar formation is a very complicated process, which is outlined in this chapter. As oral and maxillofacial surgeons we have a duty to produce unsightly scars. Scar management includes prevention, pre-injury treatments during the healing period and definitive treatment once the scar is established. This chapter outlines multiple non-surgical remedies that can be used to manage scars including: steroid, 5 FU, dermabrasion, subcision, fillers, lasers, radiation and emulsified scar rejuvenation. Furthermore, we explain surgical techniques that can be incorporated in the scar management including Z-plasty, W plasty, irregular line closures and V-Y plasty and Y-V plasty. The algorithm at the end of this chapter is used to summarise method or combination of methods that is used to treat different scars including invisible scars, stretched scars, depressed scars, hypertrophic scars and keloid scars. This algorithm provides a good review of all different treatment modalities used in scar management.
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Téot, Luc, Claude Roques, Sami Otman, Antonio Brancati, and Rainer Mittermayr. "Managing Scars: Measurements to Improve Scar Management." In Measurements in Wound Healing, 291–312. London: Springer London, 2012. http://dx.doi.org/10.1007/978-1-4471-2987-5_15.

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Jaspers, M. E. H., and P. Moortgat. "Objective Assessment Tools: Physical Parameters in Scar Assessment." In Textbook on Scar Management, 149–58. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-44766-3_17.

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AbstractObjective assessment tools can be used to evaluate whether (new) scar treatment is effective and to monitor the scar’s response to interventions in clinical practice. It is important to take the clinimetric properties of each tool into account, especially when used for the follow-up of an individual patient. An overview is provided for three important physical scar parameters that can be assessed by noninvasive objective tools: color, elasticity, and perfusion. To assess the color of a scar, an array of tools is available, all using reflectance spectroscopy and determining color by measuring the intensity of reflected light of specific wavelengths. The handheld DSM III ColorMeter offers read-out of erythema and melanin index values as well as CIEL∗a∗b values. The interrater reliability is best for the parameter a∗ of the DSM III ColorMeter. To assess scar elasticity, the Cutometer is the most widely used tool. Scar deformation is measured using negative pressure and reflected in relative and absolute elasticity parameters. On the contrary, firmness or hardness of scar tissue can be quantified by tonometry, a technique that works by exerting pressure on the skin. Lastly, it is of interest to measure scar blood flow (i.e., perfusion) as several treatment regimens work by destructing the microvasculature and/or reducing the blood flow to enhance shrinkage of hypertrophic scar tissue. Laser Doppler imaging and laser speckle imaging can be used to quantify and visualize scar blood flow, but a thorough clinimetric evaluation of these tools in scars is not performed yet.
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Ogawa, Rei. "Mechanobiology of Cutaneous Scarring." In Textbook on Scar Management, 11–18. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-44766-3_2.

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AbstractThe last phase of cutaneous wound healing produces the scar. Under normal circumstances, the immature scar then undergoes the scar maturation process over several months. This process involves tissue remodeling, which associates with a natural decrease in the inflammation and the numbers of blood vessels, collagen fibers, and fibroblasts. However, sometimes the scar maturation process is not properly engaged because inflammation continues in the scar. Consequently, the immature scar stage is prolonged. This results in the pathological scars called hypertrophic scars and keloids. Many factors that prolong the inflammatory stage have been identified. However, multiple lines of evidence acquired in recent years suggest that mechanical force can be an important cause of pathological scar development.
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Ogawa, Rei. "Japan Scar Workshop (JSW) Scar Scale (JSS) for Assessing Keloids and Hypertrophic Scars." In Textbook on Scar Management, 133–40. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-44766-3_15.

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AbstractThe Vancouver scar scale, the Manchester scar scale, and the Patient and Observer Scar Assessment Scale (POSAS) are all very well-known scar evaluation methods. These tools are based on a number of scar variables, including color, height, and pliability. However, since all were mainly developed to evaluate burn scars, they are difficult to use in clinical practice for keloids and hypertrophic scars. This is because these pathological scars require both differential diagnosis and a way to evaluate their response to therapy. The Japan Scar Workshop (JSW) has sought to develop a scar assessment scale that meets these clinical needs. The first version of this scar assessment tool was named the JSW scar scale (JSS), and it was reported in 2011. In 2015, the revised second version was reported. The JSS consists of two tables. One is a scar classification table that is used to determine whether the scar is a normal mature scar, a hypertrophic scar, or a keloid. This grading system helps the user to select the most appropriate treatment method for the scar. The other table in the JSS is an evaluation table that is used to judge the response to treatment and for follow-up. Both tables contain sample images of each subjective keloid/hypertrophic scar item that allow the user to evaluate each item without hesitation.
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Vinaik, Roohi, Joel Fish, and Marc G. Jeschke. "Burn Hypertrophic Scar in Pediatric Patients: Clinical Case." In Textbook on Scar Management, 517–21. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-44766-3_60.

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AbstractRecent improvements in burn care have resulted in greater patient survival of severe burns. With improved survival, treatment of the resulting permanent burn hypertrophic scars requires extensive care. Hypertrophic scarring occurs due to aberrations in the normal healing process, resulting in excessive inflammation and collagen deposition at the site of injury. These scars are accompanied by symptoms such as pain, pruritus, erythema, and limited mobility. The high scar prevalence in pediatric patients and accompanying physical, psychological, and social burden warrant a better understanding of the possible treatment options. Currently, several therapeutic strategies exist for hypertrophic scar management in the pediatric patient, although none are completely effective. Recently, laser therapy has emerged as a potential therapy for symptomatic relief and scar modulation. Here, we provide an up-to-date review of treatment options for hypertrophic scars in the pediatric population. In addition, we discuss a clinical case, outlining the potential merits of addition of laser therapy and surgical revision for the treatment of hypertrophic scars.
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Mustoe, Thomas A. "International Scar Classification in 2019." In Textbook on Scar Management, 79–84. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-44766-3_9.

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AbstractScars can be classified into immature scars and mature scars. Mature scars can be “normal,” atrophic, or hypertrophic. Keloids occur in patients with a genetic predisposition and behave differently than hypertrophic scars, although there can be a continuum in terms of appearance. The molecular mechanisms of scarring, hypertrophic scar and keloids, have been the subject of intensive research. There are still many unanswered questions.
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Harper, A. Breeze. "Prologue." In Scars, 1–4. Rotterdam: SensePublishers, 2014. http://dx.doi.org/10.1007/978-94-6209-761-2_1.

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Harper, A. Breeze. "Chapter Nine." In Scars, 91–106. Rotterdam: SensePublishers, 2014. http://dx.doi.org/10.1007/978-94-6209-761-2_10.

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Harper, A. Breeze. "Chapter Ten." In Scars, 107–11. Rotterdam: SensePublishers, 2014. http://dx.doi.org/10.1007/978-94-6209-761-2_11.

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Conference papers on the topic "Scar60"

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Perdanakusuma, Ardea Ramadhanti, Iswinarno Doso Saputro, and Diah Mira Indramaya. "Hypertrophic Scars Cause Burn Injuries Assessed by the Vancouver Scar Scale." In Surabaya International Physiology Seminar. SCITEPRESS - Science and Technology Publications, 2017. http://dx.doi.org/10.5220/0007341204970500.

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Hayenga, Mitchell, Natalie Enright Jerger, and Mikko Lipasti. "SCARAB." In the 42nd Annual IEEE/ACM International Symposium. New York, New York, USA: ACM Press, 2009. http://dx.doi.org/10.1145/1669112.1669144.

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Jin, Ruoming, Ning Ruan, Saikat Dey, and Jeffrey Yu Xu. "SCARAB." In the 2012 international conference. New York, New York, USA: ACM Press, 2012. http://dx.doi.org/10.1145/2213836.2213856.

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von Radziewsky, Luisa, Antonio Krüger, and Markus Löchtefeld. "Scarfy." In TEI '15: Ninth International Conference on Tangible, Embedded, and Embodied Interaction. New York, NY, USA: ACM, 2015. http://dx.doi.org/10.1145/2677199.2680568.

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Verostko, Roman. "Scarab series." In ACM SIGGRAPH 97 Visual Proceedings: The art and interdisciplinary programs of SIGGRAPH '97. New York, New York, USA: ACM Press, 1997. http://dx.doi.org/10.1145/259081.259165.

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Shiomi, Masahiro, Kasumi Abe, Yachao Pei, Narumitsu Ikeda, and Takayuki Nagai. ""I'm Scared"." In HAI '16: The Fourth International Conference on Human Agent Interaction. New York, NY, USA: ACM, 2016. http://dx.doi.org/10.1145/2974804.2980493.

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Tremas, Thierry, Magdeleine C. Dinguirard, Jean-Philippe Duvel, Patrick Raberanto, and Francis E. Sirou. "Comparison of SCARAB FM1 and SCARAB FM2 calibration performances." In SPIE's International Symposium on Optical Science, Engineering, and Instrumentation, edited by William L. Barnes. SPIE, 1999. http://dx.doi.org/10.1117/12.363539.

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Shannigrahi, Susmit, Chengyu Fan, and Christos Papadopoulos. "SCARI." In ICN '18: 5th ACM Conference on Information-Centric Networking. New York, NY, USA: ACM, 2018. http://dx.doi.org/10.1145/3267955.3269021.

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Shannigrahi, Susmit, Chengyu Fan, and Christos Papadopoulos. "SCARI." In AINTEC '18: ASIAN INTERNET ENGINEERING CONFERENCE. New York, NY, USA: ACM, 2018. http://dx.doi.org/10.1145/3289166.3289167.

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Vegni, Anna Maria, Valeria Loscrí, and Riccardo Petrolo. "SCARF." In the 3rd Workshop. New York, New York, USA: ACM Press, 2017. http://dx.doi.org/10.1145/3127502.3127512.

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Reports on the topic "Scar60"

1

Holden, Richard, Anup Malani, and Chris Teh. Allocating Scarce Information. Cambridge, MA: National Bureau of Economic Research, March 2022. http://dx.doi.org/10.3386/w29846.

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Hults, Chad, Jeffrey Coe, and Nikita Avdievitch. Fractures, scarps, faults, and landslides mapped using LiDAR, Glacier Bay National Park and Preserve, Alaska. National Park Service, 2023. http://dx.doi.org/10.36967/2300706.

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This map of fractures, scarps, faults, and landslides was completed to identify areas in Glacier Bay National Park and Preserve that may present a landslide-generated tsunami hazard. To address the potential of landslide and tsunami hazards in the park, the National Park Service (NPS) and the US Geological Survey (USGS) partnered to conduct a multi-year hazard assessment of Glacier Bay National Park and Preserve. To produce the map described in this report, we used the newly acquired (2019-2020) light detection and ranging (LiDAR) 0.5 to 1.0 m digital elevation models (DEMs) that cover all the coastal areas of the park and extend up to the ridgetops in places with steep slopes. A bare earth DEM was used to identify and map areas of incipient landslides (i.e., fractures and scarps), fault scarps, and areas where landslides have clearly occurred in the past (i.e., areas where scars and deposits are clearly visible). This map provides a baseline data set that can be used to aid forecasts of where landslides are most likely to occur in the future.
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Kandel, R., M. Viollier, P. Raberanto, J. Ph Duvel, L A Pakhomov, V. A. Golovko, A. Trishchenko, J. Mueller, E. Raschke, and R. Stuhlmann. The ScaRaB Earth Radiation Budget Dataset. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1998. http://dx.doi.org/10.4095/219774.

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Vos, Rob, Joseph W. Glauber, Manuel A. Hernandez, and David Laborde Debucquet. COVID-19 and food inflation scares. Washington, DC: International Food Policy Research Institute, 2022. http://dx.doi.org/10.2499/9780896294226_10.

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Bridges, Kate. She's the Difference: Scared, Burdened, Yet Hopeful. Washington, DC: AARP Research, November 2023. http://dx.doi.org/10.26419/res.00594.002.

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Peyer, Polly A. Hollow Force: Scare or Dare? Fort Belvoir, VA: Defense Technical Information Center, April 1994. http://dx.doi.org/10.21236/ada288663.

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Brophy, Kenny, and Alison Sheridan, eds. Neolithic Scotland: ScARF Panel Report. Society of Antiquaries of Scotland, June 2012. http://dx.doi.org/10.9750/scarf.06.2012.196.

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The main recommendations of the Panel report can be summarised as follows: The Overall Picture: more needs to be understood about the process of acculturation of indigenous communities; about the Atlantic, Breton strand of Neolithisation; about the ‘how and why’ of the spread of Grooved Ware use and its associated practices and traditions; and about reactions to Continental Beaker novelties which appeared from the 25th century. The Detailed Picture: Our understanding of developments in different parts of Scotland is very uneven, with Shetland and the north-west mainland being in particular need of targeted research. Also, here and elsewhere in Scotland, the chronology of developments needs to be clarified, especially as regards developments in the Hebrides. Lifeways and Lifestyles: Research needs to be directed towards filling the substantial gaps in our understanding of: i) subsistence strategies; ii) landscape use (including issues of population size and distribution); iii) environmental change and its consequences – and in particular issues of sea level rise, peat formation and woodland regeneration; and iv) the nature and organisation of the places where people lived; and to track changes over time in all of these. Material Culture and Use of Resources: In addition to fine-tuning our characterisation of material culture and resource use (and its changes over the course of the Neolithic), we need to apply a wider range of analytical approaches in order to discover more about manufacture and use.Some basic questions still need to be addressed (e.g. the chronology of felsite use in Shetland; what kind of pottery was in use, c 3000–2500, in areas where Grooved Ware was not used, etc.) and are outlined in the relevant section of the document. Our knowledge of organic artefacts is very limited, so research in waterlogged contexts is desirable. Identity, Society, Belief Systems: Basic questions about the organisation of society need to be addressed: are we dealing with communities that started out as egalitarian, but (in some regions) became socially differentiated? Can we identify acculturated indigenous people? How much mobility, and what kind of mobility, was there at different times during the Neolithic? And our chronology of certain monument types and key sites (including the Ring of Brodgar, despite its recent excavation) requires to be clarified, especially since we now know that certain types of monument (including Clava cairns) were not built during the Neolithic. The way in which certain types of site (e.g. large palisaded enclosures) were used remains to be clarified. Research and methodological issues: There is still much ignorance of the results of past and current research, so more effective means of dissemination are required. Basic inventory information (e.g. the Scottish Human Remains Database) needs to be compiled, and Canmore and museum database information needs to be updated and expanded – and, where not already available online, placed online, preferably with a Scottish Neolithic e-hub that directs the enquirer to all the available sources of information. The Historic Scotland on-line radiocarbon date inventory needs to be resurrected and kept up to date. Under-used resources, including the rich aerial photography archive in the NMRS, need to have their potential fully exploited. Multi-disciplinary, collaborative research (and the application of GIS modelling to spatial data in order to process the results) is vital if we are to escape from the current ‘silo’ approach and address key research questions from a range of perspectives; and awareness of relevant research outside Scotland is essential if we are to avoid reinventing the wheel. Our perspective needs to encompass multi-scale approaches, so that ScARF Neolithic Panel Report iv developments within Scotland can be understood at a local, regional and wider level. Most importantly, the right questions need to be framed, and the right research strategies need to be developed, in order to extract the maximum amount of information about the Scottish Neolithic.
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Williamson, Stephen. Scarce Collateral, the Term Premium, and Quantitative Easing. Federal Reserve Bank of St. Louis, 2014. http://dx.doi.org/10.20955/wp.2014.008.

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Chari, Anusha, and Jennifer Rhee. The Return to Capital in Capital-Scarce Countries. Cambridge, MA: National Bureau of Economic Research, August 2020. http://dx.doi.org/10.3386/w27675.

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Bohle, Sanat, Julie Webster, Matthew Hiett, and Nicholas Josefik. Facility energy performance benchmarking in a data-scarce environment. Construction Engineering Research Laboratory (U.S.), September 2017. http://dx.doi.org/10.21079/11681/24344.

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