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1

Mathematical modeling and scale-up of liquid chromatography. Berlin: Springer, 1995.

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2

1946-, Seaver Sally S., ed. Commercial production of monoclonal antibodies: A guide for scale-up. New York: M. Dekker, 1987.

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3

Lars, Hagel, ed. Handbook of process chromatography: A guide to optimization, scale up, and validation. San Diego: Academic Press, 1997.

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4

Minato, Ray. Reactor scale-up of copper-chlorine cycle of hydrogen production from proof-of-principle to large engineering scale. Norwich, N.Y.]: Knovel, 2012.

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5

1943-, Fink David J., Curran Linda M. 1950-, Allen Billy R. 1948-, National Science Foundation (U.S.), and Battelle Memorial Institute, eds. Research needs in non-conventional bioprocess: Proceedings of the Workshop on Bioprocess Scale-Up, held at Battelle's Columbus Laboratories, December 12-13, 1983. Columbus, Ohio: Battelle Press, 1985.

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6

India, Reserve Bank of. Report of the study group to examine the issues relating to the setting up of soft loan assistance fund for rehabilitation of sick small scale industrial units. Bombay: Reserve Bank of India, Rural Planning and Credit Dept., 1985.

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7

Industrial Process Scale-up. Elsevier, 2013. http://dx.doi.org/10.1016/c2012-0-07045-7.

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8

Industrial Process Scale-Up. Elsevier, 2019. http://dx.doi.org/10.1016/c2018-0-00308-4.

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9

Tarleton, Stephen, and Richard Wakeman. Solid/Liquid Separation: Scale-Up of Industrial Equipment. Elsevier Science & Technology Books, 2011.

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10

Solid/Liquid Separation: Scale-up of Industrial Equipment. Elsevier Science, 2005.

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11

Medici, Franco, ed. Recovery of Waste Materials: Technological Research and Industrial Scale-Up. MDPI, 2022. http://dx.doi.org/10.3390/books978-3-0365-3063-5.

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12

Harmsen, Jan. Industrial Process Scale-Up: A Practical Innovation Guide from Idea to Commercial Implementation. Elsevier, 2013.

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13

Harmsen, Jan. Industrial Process Scale-Up: A Practical Innovation Guide from Idea to Commercial Implementation. Elsevier, 2019.

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14

Harmsen, Jan. Industrial Process Scale-Up: A Practical Innovation Guide from Idea to Commercial Implementation. Elsevier, 2019.

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15

Harmsen, Jan. Industrial Process Scale-Up: A Practical Innovation Guide from Idea to Commercial Implementation. Elsevier, 2013.

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16

Bonem, Joe M. Chemical Projects Scale Up: How to Go from Laboratory to Commercial. Elsevier Science & Technology Books, 2018.

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17

Chemical Projects Scale Up: How to Go from Laboratory to Commercial. Elsevier Science & Technology, 2018.

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18

Fink, David J., and Linda M. Curran. Research Needs in Non-Conventional Bioprocesses: Proceedings of the Workshop on Bioprocess Scale-Up. Battelle Pr, 1985.

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19

Majumdar, Sumit K. India’s Mixed Economy Experiments. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780199641994.003.0005.

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This chapter describes the evolution of India’s industrial structure. Unlike industrialization carried out through large state-owned firms, or industrialization through a cadre of large private corporations, or industrialization through a network of small firms, many alternative organizational dynamics play simultaneously in the Indian system. The system consists of many private businesses that constitute the large-scale industrial sector. Policies were put in place to develop the molecular economy and to develop State-owned firms investing in large-scale units. These policies led to the emergence of important and dynamic segments making up India’s heterogeneous model of capitalism. Each has been in coexistence with the other and added variety to the economy. In the quest for economic progress, if Indian society was to be industrialized, modernized, autonomous, self-reliant, able to defend itself, and an independent center of economic power, State-directed industrialization was realized as a key solution for national development.
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20

Brophy, James M. The End of the Economic Old Order: the Great Transition, 1750–1860. Edited by Helmut Walser Smith. Oxford University Press, 2012. http://dx.doi.org/10.1093/oxfordhb/9780199237395.013.0008.

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This article focuses on economic history, the old order in German society, and the Great Economic Transition. The industrial ‘take-off’ of the 1840s and 1850s introduced a scale of production that forever changed the material conditions of Germany. The belching smokestacks of factories and locomotives might have tokened swift change, but the foundations for industrial capitalism were long in preparation. This article focuses on this long-term transition toward Germany's modern economy, examining how agriculture and market economies shaped the socioeconomic formations of proto-industrialization, urbanization, and industrialization. No one factor or sector suffices as an interpretive key to explain Germany's transformation. An analysis of the agrarian society, followed by urbanization and industrialization of the German society winds up this article.
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21

Morrison, Catherine J. Unraveling the Productivity Growth Slowdown in the U.S., Canada and Japan: The Effects of Subequilibrium, Scale Economies and Mark-Up (Working Paper). Natl Bureau of Economic Res, 1989.

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22

Rohling, Eelco J. The Climate Question. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780190910877.001.0001.

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In 2015, annual average atmospheric carbon dioxide (CO2) levels surpassed a level of 400 parts per million (ppm) for the first time in three million years. This has caused widespread concern among climate scientists, and not least among those that work on natural climate variability in prehistoric times, before humans. These people are known as "past climate" or palaeoclimate researchers, and author Eelco J. Rohling is one of them. The Climate Question offers a background to these concerns in straightforward terms, with examples, and is motivated by Rohling's personal experience in being intensely quizzed about whether modern change is not all just part of a natural cycle, whether nature will not simply resolve the issue for us, or whether it won't be just up to some novel engineering to settle things quickly. This book discusses in straightforward terms why climate changes, how it has changed naturally before the industrial revolution made humans important, and how it has changed since then. It compares the scale and rapidity of variations in pre-industrial times with those since the industrial revolution, infers the extent of humanity's impacts, and looks at what these may lead to in the future. Rohling brings together both data and process understanding of climate change. Finally, the book evaluates what Mother Nature could do to deal with the human impact by itself, and what our options are to lend her a hand.
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23

Rotella, Carlo. The Cult of Micky Ward in Massachusetts. University of Illinois Press, 2017. http://dx.doi.org/10.5406/illinois/9780252037610.003.0015.

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This chapter focuses on the cult of Micky Ward, the boxer from Lowell, Massachusetts, whose story is told in the 2010 film The Fighter. The cult of Micky Ward, rooted in the Boston area, is one of many local or regional cults that spring up around a sports figure understood to embody virtues especially tied to a place. Thanks in large part to The Fighter, however, this particular cult has gone global. The chapter first provides an overview of Ward's boxing career before discussing The Fighter, which stars Mark Wahlberg. Offering a rich, historically inflected reading of Ward and The Fighter, the chapter traces “large-scale flows of resources, power, people, and meanings.” It explains: “To talk about Micky Ward is to talk not only about some really stirring ass whippings, but also about major historical transformations that extend far beyond eastern Massachusetts.” Among them are “tribal pride,” industrial urbanism, and a particular kind of manhood.
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24

Roberts, Patrick. Tropical Forests in Prehistory, History, and Modernity. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198818496.001.0001.

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In popular discourse, tropical forests are synonymous with 'nature' and 'wilderness'; battlegrounds between apparently pristine floral, faunal, and human communities, and the unrelenting industrial and urban powers of the modern world. It is rarely publicly understood that the extent of human adaptation to, and alteration of, tropical forest environments extends across archaeological, historical, and anthropological timescales. This book is the first attempt to bring together evidence for the nature of human interactions with tropical forests on a global scale, from the emergence of hominins in the tropical forests of Africa to modern conservation issues. Following a review of the natural history and variability of tropical forest ecosystems, this book takes a tour of human, and human ancestor, occupation and use of tropical forest environments through time. Far from being pristine, primordial ecosystems, this book illustrates how our species has inhabited and modified tropical forests from the earliest stages of its evolution. While agricultural strategies and vast urban networks emerged in tropical forests long prior to the arrival of European colonial powers and later industrialization, this should not be taken as justification for the massive deforestation and biodiversity threats imposed on tropical forest ecosystems in the 21st century. Rather, such a long-term perspective highlights the ongoing challenges of sustainability faced by forager, agricultural, and urban societies in these environments, setting the stage for more integrated approaches to conservation and policy-making, and the protection of millennia of ecological and cultural heritage bound up in these habitats.
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25

Jaramillo, Marcela, and Valentina Saavedra. NDC Invest: Supporting Transformational Climate Policy and Finance. Inter-American Development Bank, 2021. http://dx.doi.org/10.18235/0003340.

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The Inter-governmental Panel on Climate Change (IPCC) indicates that meeting the Paris Agreement's goal of limiting the global temperature rise from pre-industrial levels to between 1.5 and 2 degrees Celsius requires reaching net-zero emissions of carbon dioxide (CO2) between 2050 and 2070, as well as deep reductions in the emissions of other greenhouse gases by around mid-century (GHGs) (IPCC, 2018). At the same time countries need to build resilience to face the changes that cannot be avoided. NDC Invest was created as the one-stop-shop of the IDB Group providing technical and financial support for countries in Latin American and Caribbean (LAC) in their efforts to achieve the climate objectives under the Paris Agreement, seeking to transition to a net zero, resilient and sustainable development pathways that improve quality of life and prosperity in LAC. Through our research and experience supporting countries and piloting solutions we have developed a toolbox for support. This paper describes three NDC Invest products to support Governments to tackle challenges and scale up action towards a climate aligned and sustainable development path: i) the design of Long-Term Strategies (LTS) for net-zero emissions and resilience; ii) design of ambitious Nationally Determined Contributions (NDCs), aligned to LTS; and iii) design of investment plans and finance strategies. Our three products are not a fix recipe, but rather a toolbox to provide flexible and relevant solutions tailored to country needs and context, and different stages of design and implementation of their climate targets.
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26

Hunt, Paul, and Ian Greaves. Oxford Manual of Major Incident Management. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199238088.001.0001.

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Regrettably, no year passes without some form of major incident occurring somewhere in the United Kingdom. To the traditional threats of transport, industrial, and natural disasters has been added the possibility of a major terrorist atrocity such as the London bombings of 7 July 2005 or the recent marauding gun attacks in Paris. The international situation continues to suggest that the likelihood of further similar attacks is a question of when, rather than if. That said, for most professional responders, a transport incident such as the GNER crash at Great Heck, a chemical incident such as Flixborough, or an environmental catastrophe like Boscastle is probably the most likely type of incident that they will be involved in. The key to a successful response lies in preparedness and effective planning built upon up-to-date knowledge and a full awareness of relevant policy and procedures. The recent enquiry into the emergency services response to ‘7/7’ highlighted a number of failings while also complementing the individuals from all services and specialities who offered aid. Although, due to the nature of this incident being especially sensitive, it is clear that the emergency services response to any incident will be subject to intense public scrutiny—both official and via the media. There is a clear need to establish a core knowledge base which extends beyond individual professional boundaries and hence the need for this manual. The Oxford Manual of Major Incident Management will, for the first time, bring together and integrate the key facts for potential emergency responders to, or who may be involved in the planning and preparation for, a major incident of any type or scale.
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27

Fuss, Sabine. The 1.5°C Target, Political Implications, and the Role of BECCS. Oxford University Press, 2017. http://dx.doi.org/10.1093/acrefore/9780190228620.013.585.

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The 2°C target for global warming had been under severe scrutiny in the run-up to the climate negotiations in Paris in 2015 (COP21). Clearly, with a remaining carbon budget of 470–1,020 GtCO2eq from 2015 onwards for a 66% probability of stabilizing at concentration levels consistent with remaining below 2°C warming at the end of the 21st century and yearly emissions of about 40 GtCO2 per year, not much room is left for further postponing action. Many of the low stabilization pathways actually resort to the extraction of CO2 from the atmosphere (known as negative emissions or Carbon Dioxide Removal [CDR]), mostly by means of Bioenergy with Carbon Capture and Storage (BECCS): if the biomass feedstock is produced sustainably, the emissions would be low or even carbon-neutral, as the additional planting of biomass would sequester about as much CO2 as is generated during energy generation. If additionally carbon capture and storage is applied, then the emissions balance would be negative. Large BECCS deployment thus facilitates reaching the 2°C target, also allowing for some flexibility in other sectors that are difficult to decarbonize rapidly, such as the agricultural sector. However, the large reliance on BECCS has raised uneasiness among policymakers, the public, and even scientists, with risks to sustainability being voiced as the prime concern. For example, the large-scale deployment of BECCS would require vast areas of land to be set aside for the cultivation of biomass, which is feared to conflict with conservation of ecosystem services and with ensuring food security in the face of a still growing population.While the progress that has been made in Paris leading to an agreement on stabilizing “well below 2°C above pre-industrial levels” and “pursuing efforts to limit the temperature increase to 1.5°C” was mainly motivated by the extent of the impacts, which are perceived to be unacceptably high for some regions already at lower temperature increases, it has to be taken with a grain of salt: moving to 1.5°C will further shrink the time frame to act and BECCS will play an even bigger role. In fact, aiming at 1.5°C will substantially reduce the remaining carbon budget previously indicated for reaching 2°C. Recent research on the biophysical limits to BECCS and also other negative emissions options such as Direct Air Capture indicates that they all run into their respective bottlenecks—BECCS with respect to land requirements, but on the upside producing bioenergy as a side product, while Direct Air Capture does not need much land, but is more energy-intensive. In order to provide for the negative emissions needed for achieving the 1.5°C target in a sustainable way, a portfolio of negative emissions options needs to minimize unwanted effects on non–climate policy goals.
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28

Szewczyk, Janusz. Rola zaburzeń w kształtowaniu struktury i dynamiki naturalnych lasów bukowo-jodłowo-świerkowych w Karpatach Zachodnich. Publishing House of the University of Agriculture in Krakow, 2018. http://dx.doi.org/10.15576/978-83-66602-35-9.

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The aim of the study was to determine the influence of different disturbances (both natural and anthropogenic) on species composition and stand structure of old-growth mixed mountain forests in the Western Carpathians. These stands are usually dominated by beech, fir and spruce, mixed in different proportions. The tree main species represent different growth strategies, and they compete against each other. The longevity of trees makes the factors influencing the stand structure difficult to identify, even during longitudinal studies conducted on permanent research plots. That is why dendroecological techniques, based upon the annual variability of tree rings, are commonly used to analyze the disturbance histories of old-growth stands. Dendroecological methods make it possible to reconstruct the stand history over several centuries in the past by analyzing the frequency, intensity, duration and spatial scale of disturbances causing the death of trees. Combining the dendroecological techniques with the detailed measurements of stand structure, snag volume, CWD volume, and the analyses of regeneration species composition and structure allows us to identify the factors responsible for the changes in dynamics of mixed mountain forests. Various disturbance agents affect some species selectively, while some disturbances promote the establishment of tree seedlings of specific species by modifying environmental conditions. Describing the disturbance regime requires a broad scope of data on stand structure, on dead wood and tree regeneration, while various factors affecting all the stages of tree growth should be taken into consideration. On the basis of the already published data from permanent sample plots, combined with the available disturbance history analyses from the Western Carpathians, three research hypotheses were formulated. 1. The species composition of mixed mountain forests has been changing for at least several decades. These directional changes are the consequence of simultaneous conifer species decline and expansion of beech. 2. The observed changes in species composition of mixed mountain forests are the effect of indirect anthropogenic influences, significantly changing tree growth conditions also in the forests that are usually considered natural or near-natural. Cumulative impact of these indirect influences leads to the decrease of fir share in the tree layer (spruce decline has also been observed recently),and it limits the representation of this species among seedlings and saplings. The final effect is the decrease of fir and spruce share in the forest stands. 3. Small disturbances, killing single trees or small groups of trees, and infrequent disturbances of medium size and intensity dominate the disturbance regime in mixed mountain forests. The present structure of beech-fir-spruce forests is shaped both by complex disturbance regime and indirect anthropogenic influences. The data were gathered in permanent sample plots in strictly protected areas of Babia Góra, Gorce, and Tatra National Parks, situated in the Western Carpathians. All plots were located in the old-growth forest stands representing Carpathian beech forest community. The results of the measurements of trees, snags, coarse woody debris (CWD) and tree regeneration were used for detailed description of changes in the species composition and structure of tree stands. Tree ring widths derived from increment cores were used to reconstruct the historical changes in tree growth trends of all main tree species, as well as the stand disturbance history within the past two to three hundred years. The analyses revealed complex disturbance history in all of the three forest stands. Intermediate disturbances of variable intensity occurred, frequently separated by the periods of low tree mortality lasting from several decades up to over one hundred years. The intervals between the disturbances were significantly shorter than the expected length of forest developmental cycle, in commonly used theories describing the dynamics of old-growth stands. During intermediate disturbances up to several dozen percent of canopy trees were killed. There were no signs of stand-replacing disturbances, killing all or nearly all of canopy trees. The periods of intense tree mortality were followed by subsequent periods of increased sapling recruitment. Variability in disturbance intensity is one of the mechanisms promoting the coexistence of beech and conifer species in mixed forests. The recruitment of conifer saplings depended on the presence of larger gaps, resulting from intermediate disturbances, while beech was more successful in the periods of low mortality. However, in the last few decades, beech seems to benefit from the period of intense fir mortality. This change results from the influence of long-term anthropogenic disturbances, affecting natural mechanisms that maintain the coexistence of different tree species and change natural disturbance regimes. Indirect anthropogenic influence on tree growth was clearly visible in the gradual decrease of fir increments in the twentieth century, resulting from the high level of air pollution in Europe. Synchronous decreases of fir tree rings’ widths were observed in all three of the sample plots, but the final outcomes depended on the fir age. In most cases, the damage to the foliage limited the competitive abilities of fir, but it did not cause a widespread increase in tree mortality, except for the oldest firs in the BGNP (Babia Góra National Park) plot. BGNP is located in the proximity of industrial agglomeration of Upper Silesia, and it could be exposed to higher level of air pollution than the other two plots. High level of fir regeneration browsing due to the deer overabundance and insufficient number of predators is the second clear indication of the indirect anthropogenic influence on mixed mountain forests. Game impact on fir regeneration is the most pronounced in Babia Góra forests, where fir was almost completely eliminated from the saplings. Deer browsing seems to be the main factor responsible for limiting the number of fir saplings and young fir trees, while the representation of fir among seedlings is high. The experiments conducted in fenced plots located in the mixed forests in BGNP proved that fir and sycamore were the most preferred by deer species among seedlings and saplings. In GNP (Gorce National Park) and TNP (Tatra National Park), the changes in species composition of tree regeneration are similar, but single firs or even small groups of firs are present among saplings. It seems that all of the analysed mixed beech-fir-spruce forests undergo directional changes, causing a systematic decrease in fir representation, and the expansion of beech. This tendency results from the indirect anthropogenic impact, past and present. Fir regeneration decline, alongside with the high level of spruce trees’ mortality in recent years, may lead to a significant decrease in conifers representation in the near future, and to the expansion of beech forests at the cost of mixed ones.
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