Academic literature on the topic 'Salmonella'

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Journal articles on the topic "Salmonella"

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Jaki Tkalec, Vesna, Željko Cvetnić, Marina Mikulić, Krunoslav Sokolić, Petra Mustapić, Jadranka Sokolović, Marija Cvetnić, Maja Kiš, and Sanja Furmeg. "Učestalost serovarova Salmonella spp. u pilećem mesu s područja sjeverozapadne Hrvatske." Veterinarska stanica 52, no. 4 (April 16, 2021): 387–96. http://dx.doi.org/10.46419/vs.52.4.11.

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Salmoneloza je jedna od najučestalijijh zoonoza koja se prenosi hranom, a najčešći izvor zaraze za ljude je kontaminirano meso i prerađevine od mesa peradi. Tijekom petogodišnjeg razdoblja od 2016. do 2020. godine provedeno je istraživanje tijekom kojeg je na Salmonellu spp., pretraženo 2457 uzoraka pilećeg mesa koje je uzorkovano u klaonicama i mesnicama na području Međimurske, Varaždinske, Koprivničko- križevačke, Bjelovarsko-bilogorske i Zagrebačke županije. Salmonella spp. je izdvojena iz 136 (5,5 %) obrađenih uzoraka. Godine 2016. ustvrđena je u 5 (6 %) pretraženih uzoraka, 2017. godine u 41 (4,7 %) uzorku, 2018. godine u 33 (6,1 %) uzorka, 2019. godine u 26 (6,6 %) uzoraka i u 2020. godini u 31 (5,4 %) uzoraka. Serološkom tipizacijom S. Infantis je identificirana u 86 (63,2 %) izdvojenih izolata; S. Typhimurium u 8 (5,9 %) izolata; a S. Enteritidis je tipizirana u 3 (2,2 %) izdvojena izolata. Tipizirani su i slijedeći serovarovi salmonela: S. Corvallis - 5 izolata (3,7 %), S. Isaszeg - 5 izolata (3,7 %), S. Derby- 3 izolata (2,2 %), S. Give - 2 izolata (2,2 %), S. Indiana - 2 izolata (2,2 %), i po 1 izolat 7 (5,1 %) serovara (S. Schwarzengrund, S. Goldcoast, S. Chester, S. Bredeney, S. Mbandaka, S.Newport, S. Saintpaul). U 15 (11 %) izolata tipizacija nije izvršena. S. Infantis je tijekom svih godina bila najčešće potvrđeni serovar. Salmoneloza predstavlja znatan gospodarski problem zbog šteta u intenzivnoj proizvodnji, ali i kao zoonoza koja se mesom i mesnim prouzvodima od mesa peradi širi na ljude. Provedbom odgovarajućih higijenskih mjera i dobre higijenske prakse od peradarskih farmi i klaonica do prodajnih mjesta moglo bi se doprinijeti manjoj kontaminaciji pilećeg mesa različitim serovarovima Salmonella spp.
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BEACH, JOHN C., ELSA A. MURANO, and GARY R. ACUFF. "Serotyping and Antibiotic Resistance Profiling of Salmonella in Feedlot and Nonfeedlot Beef Cattle." Journal of Food Protection 65, no. 11 (November 1, 2002): 1694–99. http://dx.doi.org/10.4315/0362-028x-65.11.1694.

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As part of a larger study to assess risk factors associated with hide and carcass contamination of beef cattle during transport to slaughter, a total of 281 salmonellae were isolated from 1,050 rectal, hide, carcass, and environmental samples. For feedlot cattle, salmonellae were recovered from 4.0% of rectal samples, 37.5% of hide samples, 19.0% of carcass samples, and 47.4% of environmental samples. For nonfeedlot cattle, salmonellae were recovered from 10.9% of rectal samples, 37.5% of hide samples, 54.2% of carcass samples, and 50.0% of environmental samples. Overall, the five serotypes most commonly associated with feedlot cattle and their environment were Salmonella Anatum (18.3% of the isolates), Salmonella Kentucky (17.5%), Salmonella Montevideo (9.2%), Salmonella Senftenberg (8.3%), and Salmonella Mbandaka (7.5%). The five serotypes most commonly associated with nonfeedlot cattle and their environment were Salmonella Kentucky (35.4%), Salmonella Montevideo (21.7%), Salmonella Cerro (7.5%), Salmonella Anatum (6.8%), and Salmonella Mbandaka (5.0%). Antimicrobial susceptibility testing of all of the isolates associated with feedlot cattle revealed that 21.7% were resistant to tetracycline, compared with 11.2% of the isolates associated with nonfeedlot cattle. None of the other isolates from feedlot cattle were resistant to any of other antimicrobial agents tested, whereas 6.2% of nonfeedlot cattle isolates were resistant to more than four of the antimicrobial agents tested.
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MOTSOELA, CYNTHIA, ERNEST K. COLLISON, and BERHANU A. GASHE. "Prevalence of Salmonella in Two Botswana Abattoir Environments." Journal of Food Protection 65, no. 12 (December 1, 2002): 1869–72. http://dx.doi.org/10.4315/0362-028x-65.12.1869.

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A 1-year study was carried out to investigate the prevalence of Salmonella in two abattoir environments coded “A” and “B” in Gaborone, Botswana. The total number of environmental samples collected from abattoirs A and B was 250 and 300, respectively. The samples were taken from soils in the corrals, knife blades, saw blades, cattle-drinking water, cattle feces, and feed. Preenrichment, enrichment, and selective/differential media, which enabled the favorable growth of Salmonella, were used in the study. Salmonellae were present in all sampled environments. The most common serotypes found in the environment at abattoir A were E1, C1, C2, and B. Serotypes B, C1, C2, C3, and E1 were common in abattoir B. Antigenic characterization of the salmonellae isolates showed that Salmonella Anatum, Salmonella Azteca, Salmonella Saintpaul, Salmonella Cerro, and Salmonella Westhampton were predominant in abattoir A, whereas Salmonella Anatum, Salmonella Mbandaka, Salmonella Molade, Salmonella Reading, and Salmonella Oranienburg were dominant in abattoir B. Implementing hazard analysis critical control point principles in work procedures would definitely reduce the gross contamination taking place in abattoirs.
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JERNGKLINCHAN, JAOWAPA, CHAILAI KOOWATANANUKUL, KRIENGSAG DAENGPROM, and KRIENGSAG SAITANU. "Occurrence of Salmonellae in Raw Broilers and Their Products in Thailand." Journal of Food Protection 57, no. 9 (September 1, 1994): 808–10. http://dx.doi.org/10.4315/0362-028x-57.9.808.

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A study was conducted to determine the presence of salmonellae in raw chicken meat, giblets (liver, heart, gizzard) and cooked chicken products (meatballs and sausages) in Bangkok. A total of 1,135 samples, collected from nine open markets, nine supermarkets and four poultry processing plants, were examined. Salmonellae were isolated from 467 (66%) of 705 chicken meat samples, 190 (86%) of 221 samples of giblets and 21 (10%) of 209 cooked products. Out of 678 tested isolates, 46 serotypes and one rough strain were found. The five most common serotypes isolated from chicken meat were Salmonella blockley, Salmonella virchow, Salmonella enteritidis, Salmonella hadar and Salmonella paratyphi B; these accounted for 14, 12, 12, 9 and 9%, respectively, of the strains isolated in this study. The major isolates from giblets were S. virchow, Salmonella Kentucky, S. enteritidis, Salmonella agona and S. blockley (15, 13, 12, 12 and 11%, respectively). Salmonella derby (33%) was the serotype most often isolated from the cooked poultry products.
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Poppe, C., R. J. Irwin, C. M. Forsberg, R. C. Clarke, and J. Oggel. "The prevalence of Salmonella enteritidis and other Salmonella spp. among Canadian registered commercial layer flocks." Epidemiology and Infection 106, no. 2 (April 1991): 259–70. http://dx.doi.org/10.1017/s0950268800048408.

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SUMMARYA survey was conducted to estimate the prevalence of Salmonella enteritidis and other salmonellas among Canadian commercial egg producing flocks. Environmental (faecal and eggbelt) samples from 152 of 295 (52·9%) randomly selected flocks were contaminated with salmonellas. Thirty-five different salmonella serovars were isolated. Eggbelt samples were more often contaminated with salmonellas than faecal samples (25·7 v. 10·1 %). The most prevalent serovars were S. heidelberg, S. infantis, S. hadar, and S. schwarzengrund; they were isolated from samples of 59/295 (20%), 18/295 (6·1%), 17/295 (5·8%), and 15/295 (5·1%) flocks, respectively. Feed samples of 21/295 (7·2%) flocks were contaminated with salmonellas. Salmonella enteritidis was isolated from the environmental samples of 8/295 (2·7%) flocks. Salmonella enteritidis phage type (PT) 8 was isolated from 5 flocks, PT 13a from 2 flocks, and PT 13 from 1 flock.
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Poppe, C., R. J. Irwin, S. Messier, G. G. Finley, and J. Oggel. "The prevalence of Salmonella enteritidis and other Salmonella spp. among Canadian registered commercial chicken broiler flocks." Epidemiology and Infection 107, no. 1 (August 1991): 201–11. http://dx.doi.org/10.1017/s0950268800048822.

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SUMMARYA nation-wide survey was conducted to estimate the prevalence of Salmonella enteritidis and other salmonellas among Canadian commercial broiler flocks. Environmental (litter and/or water) samples from 226 of 294 (76·9%) randomly selected flocks were contaminated with salmonellas. Litter samples were more often contaminated with salmonellas than water samples (47·4 ν 12·3%). Fifty different salmonella serovars were isolated. The most prevalent serovars were S. hadar, S. infantis, and S. schwarzengrund; they were isolated from samples of 98/294 (33·3%), 26/294 (8·8%), and 21/294 (7·1%) flocks, respectively. Feed samples of 39/290 (13·4%) flocks were contaminated with salmonellas. Salmonella enteritidis was isolated from the environmental samples of 9/294 (3·1%) flocks. Salmonella enteritidis phage type (PT) 8 was isolated from seven flocks, and PT 13a from two flocks.
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Mandal, B. K. "Salmonella typhi and other salmonellas." Gut 35, no. 6 (June 1, 1994): 726–28. http://dx.doi.org/10.1136/gut.35.6.726.

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Feglo, P. K., and M. P. Dakorah. "Contribution of Dug-Out Wells to Salmonella Dissemination in Kwaebibirem District of Ghana." European Scientific Journal, ESJ 13, no. 6 (February 28, 2017): 124. http://dx.doi.org/10.19044/esj.2017.v13n6p124.

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Typhoid fever is rare in the developed world, but in Kwaebibirem District of Ghana, Salmonella infections are very common. Typhoid and paratyphoid fevers in addition to gastroenteritis are frequently reported. The reservoir, prevailing Salmonella species and their antimicrobial susceptibility patterns are not known, but in Ghana treatment of these infections are mostly empirical. 464 samples (270 stool and 194 blood) were collected from patients and 188 water samples were collected from different water sources in Kwaebibirem District and cultured for Salmonella at St. Dominic Hospital, Akwatia. Salmonella prevalence of 11.6% (54/464) among patients and 2.7% (5/188) from dug-out wells were obtained. Total viable bacterial count in the water samples averaged 2.56 x103 -1.2 x 1013per milliliter. Five (5) out of 51 (9.8%) dug-out wells yielded Salmonellae upon culture. Typhoidal Salmonellae [11% (6/54)] and 68.6% (38/54) non-typhoidal Salmonellae were isolated from patients. The most affected age group ranged 6-15years with prevalence of 42.6% (23/54). The most frequent isolated was Salmonella Typhi 20% (11/54) followed by Salmonella Enterica, 29.6% (16/54). The Salmonella isolates were all susceptible to the cephalosporins (cefoxitin, cefotaxime, cefepime) the carbapenems (imipenem and meropenem) the quinolones (norfloxacin and ciprofloxacin) and the aminoglycoside (amikacin). Their resistant proportions to other drugs were ampicillin (69.5%), piperacillin (69.5%) and co-trimoxazole (76.3%). Salmonella infections were common in Kwaebibirem District, and home owned dug-out wells posed risk of Salmonella transmission to the people.
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Akinyemi, Kabiru O., Samuel O. Ajoseh, and Christopher O. Fakorede. "A systemic review of literatures on human Salmonella enterica serovars in Nigeria (1999-2018)." Journal of Infection in Developing Countries 15, no. 09 (September 30, 2021): 1222–35. http://dx.doi.org/10.3855/jidc.12186.

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Introduction: Salmonella infections are endemic in Nigeria. There is lack of reliable data on culture-positive Salmonella with national coverage. This systemic review of literatures was undertaken to aggregate data on culture proven cases of human Salmonellae and to determine the prevailing serotypes for disease burden estimations. Methodology: This involved comprehensive search engines of Pubmed, Google Scholar, Google and Embase for the literatures on culture positive human Salmonellae from 1999-2018. This review documented the prevalence, common Salmonella serotypes. antibiotic resistance and risk factors associated with human Salmonella infections. Results: This study revealed that 21out of 36 States in Nigeria reported Salmonella-associated diseases, spanning the six geopolitical zones. Our study revealed prevalence of 1.9% (2,732/143,756) Salmonella-bacteraemia and 16.3% (1,967/12,081) Salmonella-associated gastroenteritis. Fifty-three 53 Salmonella serotypes were identified. 39 serotypes were associated with Salmonella-bacteraemia and 31 serotypes with Salmonella-gastroenteritis. Salmonella typhi remains the commonest serotype accounting for 85.2% for Salmonella-bacteraemia and 73.1% Salmonella-gastroenteritis. S. typhimurium (3.8%) was mostly implicated invasive non-typhoidal serotype followed S. enteritidis (2.8%) among others. Human Immunodeficiency Virus-infected individuals, malnutrition was among factors predisposing Salmonella infections. Over 60% of the reported Salmonella isolates developed resistance to two or more of 23 antibiotics recorded, mostly ampicillin, cotrimoxazole, tetracycline and amoxicillin. Conclusions: This study revealed 39 Invasive and 31 non-invasive Salmonella serotypes. Ampicillin, cotrimoxazole, amoxicillin-clavulanate and tetracycline are the most frequently reported antibiotics resisted by Salmonella isolates. This antimicrobial resistance exhibited poses a threat to public health. Data generated from this review would serve as a baseline information for future surveillance studies.
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SHIROTA, KAZUTOSHI, HIROMITSU KATOH, TOSHIYUKI MURASE, TOSHIHIRO ITO, and KOICHI OTSUKI. "Monitoring of Layer Feed and Eggs for Salmonella in Eastern Japan between 1993 and 1998." Journal of Food Protection 64, no. 5 (May 1, 2001): 734–37. http://dx.doi.org/10.4315/0362-028x-64.5.734.

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In order to investigate contamination of chicken farms with Salmonella, feed and eggs were sampled from 16 commercial layer farms in eastern Japan between 1993 and 1998 and cultured for salmonellae. Salmonella enterica subsp. enterica isolates belonging to 19 serovars were obtained from the feed. Six of the 19 serotypes, including Salmonella serovar Enteritidis, were observed in isolates recovered from the eggs. Salmonella serovar Enteritidis strains obtained from a feed sample and egg contents in a layer farm showed pulsed-field gel electrophoresis patterns that were genetically related and belonged to a single phage type, suggesting that the contamination of the farms was linked to the occurrence of salmonellae in feed.
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Dissertations / Theses on the topic "Salmonella"

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Oliveira, Gláucia Helaine de [UNESP]. "Ensaios imunoenzimáticos (ELISA) para detecção da resposta sorológica contra Salmonella Gallinarum, Salmonella Pullorum, Salmonella Enteritidis e Salmonella Typhimurium em aves." Universidade Estadual Paulista (UNESP), 2004. http://hdl.handle.net/11449/104648.

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Made available in DSpace on 2014-06-11T19:33:26Z (GMT). No. of bitstreams: 0 Previous issue date: 2004-02-17Bitstream added on 2014-06-13T19:04:11Z : No. of bitstreams: 1 oliveira_gh_dr_jabo.pdf: 314775 bytes, checksum: 0fd8bccb749e336852eff962616e3d04 (MD5)
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Foi desenvolvido um ensaio imunoenzimático do tipo ELISA indireto para a detecção de resposta sorológica de aves para Salmonella sorotipos Gallinarum, Pullorum, Enteritidis e Typhimurium. Utilizou-se antígeno solúvel obtido por meio de sonicação de cultura de Salmonella Gallinarum (AgSG), Salmonella Enteritidis cepa aflagelar (AgSE) e Salmonella Typhimuirum cepa aflagelar (AgTM), os conjugados peroxidase e fosfatase alcalina e amostras de soros positivos e negativos de vários sorotipos de salmonelas. Os resultados demonstraram que o AgSG pode ser utilizado diluído a 1:25.000 (peroxidase e fosfatase alcalina). Observou-se que o ELISA contendo S. Gallinarum como antígeno e fosfatase alcalina como enzima, propicia a separação de reações positivas para Gallinarum e Pullorum de Enteritidis. O AgSE pode ser utilizado diluído a 1:10.000 (peroxidase) ou 1:5.000 (fosfatase alcalina). Nestas condições, o ELISA/AgSE detectou resposta sorológica para os sorotipos Enteritidis, Gallinarum e Pullorum. O ELISA com o AgTM demonstrou que o antígeno pode ser diluído a 1:20.000 para ambos os conjugados. O ELISA/AgTM demonstrou reatividade entre salmonelas dos grupos B e D. Todas as amostras de soros testes devem ser analisadas diluídas a 1:1.000. Concluindo, o ELISA mostrou-se um teste útil para identificar aves com reação sorológica contra S. Gallinarum, S. Pullorum, S. Enteritidis e S. Typhimurium, podendo ainda identificar aves com sorologia positiva para S. Gallinarum, S. Pullorum sem que haja reação cruzada com amostras de soro de aves vacinadas ou infectada por S. Enteritidis.
This study was done to assess the enzyme-linked immunosorbent assays (ELISA) for detection chicken serologic response against Salmonella enterica sorotypes Gallinarum, Pullorum, Enteritidis and Typhimurium. The test was performed using soluble proteins from Salmonella Gallinarum strain 9 (AgSG), from non-flagellate Salmonella Enteritidis strain (AgSE) and from not flagellate Salmonella Typhimurium (AgTM) strain as detecting antigen and peroxidase and alkaline phosphatase enzymes, as conjugate. According to the results, the antigen has to be diluted at 1:25.000 (AgSG, peroxidase and alkaline phosphatase). In addition, using alkaline phosphatase enzyme, the assay was helpful to separate positive serological reaction to serotypes Gallinarum and Pullorum from Enteritidis. To the ELISA/AgSE, the antigen has to be diluted at 1:10.000 for peroxidase assay and at 1:5.000 for alkaline phosphatase assay. In this condition, the ELISA/AgSE can detect serological reaction to S. Enteritidis, S. Gallinarum and S. Pullorum. To the ELISA/AgTM the antigen has to be diluted at 1:20.000 to both enzymes. In this condition the ELISA/AgTM showed sensibility but was no possible to separate positive serological reaction to serotype concerning at the group B and group D. In all test, the sample of serum has to be diluted at 1:1.000. Therefore, the ELISA was able to identity reactors birds to Salmonella antigens and also to detect serological response to S. Gallinarum, S. Pullorum antigen with no cross-reaction with serum samples taken from birds either challenged or vaccinated against S. Enteritidis.
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Oliveira, Gláucia Helaine de. "Ensaios imunoenzimáticos (ELISA) para detecção da resposta sorológica contra Salmonella Gallinarum, Salmonella Pullorum, Salmonella Enteritidis e Salmonella Typhimurium em aves /." Jaboticabal : [s.n.], 2004. http://hdl.handle.net/11449/104648.

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Resumo: Foi desenvolvido um ensaio imunoenzimático do tipo ELISA indireto para a detecção de resposta sorológica de aves para Salmonella sorotipos Gallinarum, Pullorum, Enteritidis e Typhimurium. Utilizou-se antígeno solúvel obtido por meio de sonicação de cultura de Salmonella Gallinarum (AgSG), Salmonella Enteritidis cepa aflagelar (AgSE) e Salmonella Typhimuirum cepa aflagelar (AgTM), os conjugados peroxidase e fosfatase alcalina e amostras de soros positivos e negativos de vários sorotipos de salmonelas. Os resultados demonstraram que o AgSG pode ser utilizado diluído a 1:25.000 (peroxidase e fosfatase alcalina). Observou-se que o ELISA contendo S. Gallinarum como antígeno e fosfatase alcalina como enzima, propicia a separação de reações positivas para Gallinarum e Pullorum de Enteritidis. O AgSE pode ser utilizado diluído a 1:10.000 (peroxidase) ou 1:5.000 (fosfatase alcalina). Nestas condições, o ELISA/AgSE detectou resposta sorológica para os sorotipos Enteritidis, Gallinarum e Pullorum. O ELISA com o AgTM demonstrou que o antígeno pode ser diluído a 1:20.000 para ambos os conjugados. O ELISA/AgTM demonstrou reatividade entre salmonelas dos grupos B e D. Todas as amostras de soros testes devem ser analisadas diluídas a 1:1.000. Concluindo, o ELISA mostrou-se um teste útil para identificar aves com reação sorológica contra S. Gallinarum, S. Pullorum, S. Enteritidis e S. Typhimurium, podendo ainda identificar aves com sorologia positiva para S. Gallinarum, S. Pullorum sem que haja reação cruzada com amostras de soro de aves vacinadas ou infectada por S. Enteritidis.
Abstract: This study was done to assess the enzyme-linked immunosorbent assays (ELISA) for detection chicken serologic response against Salmonella enterica sorotypes Gallinarum, Pullorum, Enteritidis and Typhimurium. The test was performed using soluble proteins from Salmonella Gallinarum strain 9 (AgSG), from non-flagellate Salmonella Enteritidis strain (AgSE) and from not flagellate Salmonella Typhimurium (AgTM) strain as detecting antigen and peroxidase and alkaline phosphatase enzymes, as conjugate. According to the results, the antigen has to be diluted at 1:25.000 (AgSG, peroxidase and alkaline phosphatase). In addition, using alkaline phosphatase enzyme, the assay was helpful to separate positive serological reaction to serotypes Gallinarum and Pullorum from Enteritidis. To the ELISA/AgSE, the antigen has to be diluted at 1:10.000 for peroxidase assay and at 1:5.000 for alkaline phosphatase assay. In this condition, the ELISA/AgSE can detect serological reaction to S. Enteritidis, S. Gallinarum and S. Pullorum. To the ELISA/AgTM the antigen has to be diluted at 1:20.000 to both enzymes. In this condition the ELISA/AgTM showed sensibility but was no possible to separate positive serological reaction to serotype concerning at the group B and group D. In all test, the sample of serum has to be diluted at 1:1.000. Therefore, the ELISA was able to identity reactors birds to Salmonella antigens and also to detect serological response to S. Gallinarum, S. Pullorum antigen with no cross-reaction with serum samples taken from birds either challenged or vaccinated against S. Enteritidis.
Orientador: Angelo Berchieri Júnior
Coorientador: Hélio José Montassier
Banca: Raul José Silva Girio
Banca: Fernando Antonio de Ávila
Banca: Paulo Lourenço da Silva
Banca: Ana Maria Iba Kanashiro
Doutor
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Buckner, Michelle M. C. "Salmonella-host interactions : the interplay between Salmonella, SPI2 and eicosanoids." Thesis, University of British Columbia, 2013. http://hdl.handle.net/2429/44738.

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Salmonella are Gram-negative facultative intracellular pathogens that cross the intestinal barrier, and are taken up by phagocytes where, they can replicate and spread to systemic sites. Salmonella encode two type III secretion systems, Salmonella pathogenicity island 1 and 2 (SPI1 and SPI2), which mediate the translocation of bacterial effectors into the host cell. SPI1 facilitates bacterial uptake into non-phagocytic cells and is involved in forming a special replicative niche, called the Salmonella containing vacuole (SCV). SPI2 is required for maintenance of the SCV, macrophage replication and systemic disease. A comprehensive study of the contribution of individual SPI2 effectors to virulence had not been previously done, and was therefore performed. Strains deficient in specific SPI2 genes were tested for alterations in virulence in a mouse model of typhoid fever, and in epithelial and macrophage cell infections. These experiments showed that many SPI2 effectors are required for replication in macrophages, and that ΔspvB, ΔssaR, and ΔspiC strains were attenuated in mice. Salmonella infection causes many perturbations to the host, including changes in metabolites, specifically arachidonic acid metabolism, which leads to the production of eicosanoids. The effects of Salmonella infection of macrophages on eicosanoids were examined. Salmonella infection increased the expression of prostaglandin synthases, but decreased thromboxane and leukotriene synthases. The SPI2 deletion strains were tested to determine involvement of SPI2 in arachidonic acid metabolism. The SPI2 effectors SseF and SseG, which are largely uncharacterized in macrophage infections, were mainly responsible for the induction of prostaglandins. The effects of prostaglandins on Salmonella infection were studied. It was found that 15-deoxy-Δ12,14-prostaglandin-J2 (15d-PGJ2) significantly reduced Salmonella colonization of macrophages, but not epithelial cells. Furthermore, this occurs independently of SPI1, SPI2, and PPAR-γ. 15d-PGJ2 reduces cytokines and reactive nitrogen species produced by infected macrophages. A role for 15d-PGJ2 in Salmonella infection has not been previously demonstrated. This thesis examines the role of SPI2 in Salmonella virulence and arachidonic acid metabolism.
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Kee, Jennifer Michelle. "Characterisation of the temperate bacteriophages of Salmonella enterica and Salmonella bongori." Thesis, Connect to e-thesis to view abstract Move to record for print version, 2008. http://theses.gla.ac.uk/113/.

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Thesis (Ph.D.) - University of Glasgow, 2008.
Ph.D. thesis submitted to the Department of Infection and Immunity, Faculty of Biomedical and Life Sciences, University of Glasgow, 2008. Includes bibliographical references. Print version also available.
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Howard, Zoe R. "Invasion of avian reproductive tissues by Salmonella typhimurium and Salmonella enteritidis." Texas A&M University, 2003. http://hdl.handle.net/1969/275.

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Miller, Irene Ann. "Virulence mechanisms of Salmonella." Thesis, University of Cambridge, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.385711.

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Stephens, Peter Jeremy. "Recovery of stressed salmonella." Thesis, University of Exeter, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.429640.

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Tran, Dien Alicia. "Génomique épidémiologique de Salmonella." Thesis, Paris, Institut agronomique, vétérinaire et forestier de France, 2018. http://www.theses.fr/2018IAVF0001/document.

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Découverte il y a plus d’un siècle, Salmonella n’a cessé d’intriguer les chercheurs. Sa capacité à résister à de nombreux antibiotiques est de plus en plus préoccupante. La surveillance de ce pathogène repose sur un typage rapide et discriminant de façon à identifier le plus précocement possible les sources alimentaires contaminées. Les méthodes classiques sont longues, lourdes et non automatisables. Comprendre l’émergence et l’évolution des Salmonella est la clé pour éradiquer ce pathogène resté l’une des premières causes de diarrhées bactériennes d’origine alimentaire dans le monde. Au cours des dernières décennies, des progrès spectaculaires ont été menés dans le monde de la microbiologie avec l’arrivée des séquenceurs de paillasse, passant du traitement d’une dizaine à des centaines de millions de séquences. L’accès facilité aux séquences génomiques et aux outils qui leurs sont dédiés sont devenus une nécessité. Les outils actuellement disponibles ne sont pas assez discriminants pour sous-typer S. enterica sérotype Typhimurium (STM), sérotype prédominant de Salmonella. Nous avons voulu lors de ce travail, montrer l’intérêt du séquençage entier du génome, pour l’étude génomique de Salmonella. (1) Après avoir séquencé plus de 300 génomes de STM, nous avons mis au point un outil de sous-typage in silico de ce sérotype, basé sur le polymorphisme des CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats). La surveillance à haut débit des salmonelloses a été validée en routine sur plus de 800 génomes. L’étude de la coévolution entre le chromosome (SNPs) et les régions CRISPR ont permis d’établir une nomenclature définissant les différentes populations de STM. (2) L’analyse génomique de 280 souches historiques de STM a montré que les gènes de bêta-lactamase conférant une résistance à l’ampicilline et portés par des plasmides étaient répandus chez STM à la fin des années 1950, bien avant l’utilisation de cet antibiotique. La présence de la pénicilline G dans le milieu agricole où ces composés ont été utilisés en tant que promoteurs de croissance ont pu conduire à la sélection des premières souches résistantes à l’ampicilline. (3) L’étude phylogénétique d’un génome issu du cadavre d’une femme décédée il y a plus de 800 ans, probablement à cause de la fièvre entérique et de 219 génomes historiques et récents des sérotypes Paratyphi C, Choleraesuis et Typhisuis ont montré que leurs génomes étaient très similaires au cours des 4000 dernières années. Ainsi, la combinaison des approches génotypique et phylogénétique ont accru nos connaissances sur l’évolution de ce pathogène.Mots clés : Séquençage entier du génome, surveillance épidémiologique, CRISPR, SNP, résistance antibiotique, phylogénie, évolution
Over a century has passed since the discovery of Salmonella and yet, this pathogen still intrigues researchers. Its ability to withstand many antibiotics is of increasing concern. The monitoring of this pathogen is based on a rapid and discriminatory typing to identify the sources of contaminated food as early as possible. The conventional methods are long, heavy and non-automatable. Understanding the emergence and evolution of Salmonella is the key to eradicate this pathogen, which has remained one of the leading causes of foodborne bacterial diarrhea in the world. During the last decades, spectacular progress has been made in the world of microbiology with the arrival of workbench sequencers, passing from a dozen to hundreds of millions of sequences processed. Facilitated access to numerous genome sequences and dedicated tools are mandatory. Tools currently available are not sufficiently discriminating for the subtype of S. enterica serotype Typhimurium, a predominant serotype of Salmonella. Throughout this study, we showed the interest of whole genome sequencing, a multidisciplinary tool, for the genomic study of Salmonella. (1) After sequencing over 300 S. enterica serotype Typhimurium genomes, we have developed an in silico subtyping tool for this serotype, based on the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) polymorphism. High-throughput microbiological monitoring of salmonellosis has been routinely validated on over 800 genomes. The study of coevolution between the chromosome (SNPs of the core genome) and the two CRISPR regions made it possible to establish a nomenclature defining the different populations of this serotype. (2) Genomic analysis of 280 historical strains of S. enterica serotype Typhimurium showed that plasmids carrying beta-lactamase genes, which confer resistance to ampicillin, were widespread within this serotype in the late 1950s, years before ampicillin was first used for clinical purposes. The presence of penicillin G in the farming environment where these compounds were used as growth promoters, may have led to the selection of the first ampicillin-resistant strains. (3) The phylogenetic study of a genome from the corpse of a young woman who died over 800 years ago, probably due to enteric fever, and 219 historical and recent genomes of the serotypes Paratyphi C, Choleraesuis and Typhisuis have shown, despite the differences in host specificity, that their genomes were very similar over the past 4000 years. Thus, the combination of genotypic and phylogenetic approaches has increased our knowledge of the evolution of this pathogen.Key words: Whole genome sequencing, epidemiological monitoring, CRISPR, SNP, antibiotic resistance, phylogeny, evolution
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Khalili, Shirin Fatima. "Biopanning for Salmonella antigens." Thesis, University of Edinburgh, 2004. http://hdl.handle.net/1842/10984.

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Of the two currently available typhoid fever vaccines, one is potentially inappropriate for immuno-compromised individuals while the other could be rendered ineffective as the pathogen evolves. This work addresses these shortcomings and explores the possibility of identifying novel antigens for use in a multiple subunit vaccine. S. enterica serovar Typhimurium infection of mice is a well-established animal model of human typhoid fever. Phage display is a method of generating particles that embody a physical link between a given DNA sequence and the polypeptide it encodes. In this work, a phage display library was constructed from random fragments of Salmonella genomic DNA. Hyper-immune serum from infected mice was used for affinity selection of potential antigens from this library in a process called biopanning. Individual clones encoding potential antigens were subjected to further screening alongside a positive and negative control, and 10 were consistently positive. Sequences encoding the potential antigens were then sub-cloned into an expression vector encoding a His tag for affinity purification.  Six of the ten sub-clones could not be induced to express the fusion peptide. Poor induction of the remaining four led to multiple purification steps. The four potential antigens were then tested by Western blot and ELISA alongside the same positive control for antigenicity. It was then found that the positive control in itself was poorly antigenic and the four candidates were not antigens. Possibilities for modification of the original affinity selection process, as well as phage-displayed positive control antigens are discussed.
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Bokanyi, Richard Paul. "Characterization of Salmonella hadar /." The Ohio State University, 1992. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487779914823965.

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Books on the topic "Salmonella"

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Schatten, Heide, and Abraham Eisenstark, eds. Salmonella. New York, NY: Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-1625-2.

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Schatten, Heide, and Abraham Eisenstark, eds. Salmonella. Totowa, NJ: Humana Press, 2007. http://dx.doi.org/10.1007/978-1-59745-512-1.

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Bell, Chris, and Alec Kyriakides, eds. Salmonella. Oxford, UK: Blackwell Science Ltd, 2001. http://dx.doi.org/10.1002/9780470999455.

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Schatten, Heide, ed. Salmonella. New York, NY: Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-0791-6.

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Bell, C. Salmonella. New York: John Wiley & Sons, Ltd., 2007.

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Hirschmann, Kris. Salmonella. San Diego: Kidhaven Press, 2004.

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Massachusetts. Department of Public Health. Salmonella. Boston, MA: Massachusetts Dept. of Public Health, 1986.

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Maskell, Duncan. Salmonella Infections. Edited by Pietro Mastroeni. Cambridge: Cambridge University Press, 2006. http://dx.doi.org/10.1017/cbo9780511525360.

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Cabello, Felipe, Carlos Hormaeche, Pasquale Mastroeni, and Letterio Bonina, eds. Biology of Salmonella. Boston, MA: Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-2854-8.

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Cabello, Felipe. Biology of Salmonella. Boston, MA: Springer US, 1993.

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Book chapters on the topic "Salmonella"

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Barrow, P. A., M. A. Jones, and N. Thomson. "Salmonella." In Pathogenesis of Bacterial Infections in Animals, 231–65. Oxford, UK: Wiley-Blackwell, 2010. http://dx.doi.org/10.1002/9780470958209.ch14.

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Lynne, Aaron M., Jing Han, and Steven L. Foley. "Salmonella." In DNA Methods in Food Safety, 337–57. Chichester, UK: John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118278666.ch14.

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Silliker, John H., and Damien A. Gabis. "Salmonella." In Advances in Meat Research, 209–29. London: Macmillan Education UK, 1986. http://dx.doi.org/10.1007/978-1-349-09145-4_7.

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Sonntag, Hans-Günther. "Salmonella." In Lexikon der Infektionskrankheiten des Menschen, 731–34. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-39026-8_974.

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Ricke, Steven C., Ok-Kyung Koo, Steven Foley, and Rajesh Nayak. "Salmonella." In Guide to Foodborne Pathogens, 112–37. Oxford: John Wiley & Sons, 2013. http://dx.doi.org/10.1002/9781118684856.ch7.

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Bailey, Stan, L. Jason Richardson, Nelson A. Cox, and Douglas E. Cosby. "Salmonella." In Pathogens and Toxins in Foods, 108–18. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555815936.ch7.

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da Silva, Neusely, Marta Hiromi Taniwaki, Valéria Christina Amstalden Junqueira, Neliane Ferraz de Arruda Silveira, Margarete Midori Okazaki, and Renato Abeilar Romeiro Gomes. "Salmonella." In Microbiological Examination Methods of Food and Water, 265–97. Second edition. | Leiden, The Netherlands ; Boca Raton : CRC Press/Balkema, [2018]: CRC Press, 2018. http://dx.doi.org/10.1201/9781315165011-19.

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Smith, S. I., A. Ajayi, and A. Seriki. "Salmonella." In Handbook of Foodborne Diseases, 409–16. Boca Raton : Taylor & Francis, [2019] | Series: Food microbiology series | “A CRC title, part of the Taylor & Francis imprint, a member of the Taylor & Francis Group, the academic division of T&F Informa plc.”: CRC Press, 2018. http://dx.doi.org/10.1201/b22030-38.

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Lewis, April M., Melanie C. Melendrez, and Ryan C. Fink. "Salmonella." In Food Microbiology, 225–62. Washington, DC, USA: ASM Press, 2019. http://dx.doi.org/10.1128/9781555819972.ch9.

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da Silva, Neusely, Marta Hiromi Taniwaki, Valéria Christina Amstalden Junqueira, Neliane Ferraz de Arruda Silveira, Margarete Midori Okazaki, and Renato Abeilar Romeiro Gomes. "Salmonella." In Microbiological Examination Methods of Food and Water, 265–97. Second edition. | Leiden, The Netherlands ; Boca Raton : CRC Press/Balkema, [2018]: CRC Press, 2017. http://dx.doi.org/10.1201/b13740-19.

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Conference papers on the topic "Salmonella"

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Cassar, C., K. Speed, G. Bennett, and Robert H. Davies. "Salmonella surveillance trends in porcine Salmonellae in GB: 1996- 2002." In Second International Symposium on Epidemiology and Control of Salmonella in Pork. Iowa State University, Digital Press, 2003. http://dx.doi.org/10.31274/safepork-180809-459.

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Silva, Gabriela Gomes Carvalho da, KEMILLE MARQUES BRANDÃO, EMERSSON ALVES VIANA, and CRISTIANE LOPES MAZZINGHY. "IMPACTOS DA SALMONELLA ENTERITIDIS E SALMONELLA TYPHIMURIUM NA SAÚDE PÚBLICA." In I Congresso Brasileiro On-line One Health. Revista Multidisciplinar em Saúde, 2022. http://dx.doi.org/10.51161/i-onehealth/10077.

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Boshara, P., and M. Kousha. "Nontyphoidal Salmonella Empyema as a Complication of Primary Salmonella Enteritidis Bacteremia." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a3895.

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Hensel, A., A. Hensel, Bernd-Alois Tenhagen, B. Appel, and A. Käsbohrer. "Salmonella in pork – Lessons to be learned from salmonella control in poultry." In Ninth International Conference on the Epidemiology and Control of Biological, Chemical and Physical Hazards in Pigs and Pork. Iowa State University, Digital Press, 2011. http://dx.doi.org/10.31274/safepork-180809-647.

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Ilea, Mihai, Andrei Gheorghita, and Marius Turnea. "DYNAMICS OF SALMONELLA TRANSMISSION USING COMPARTMENTAL MODELS." In eLSE 2019. Carol I National Defence University Publishing House, 2019. http://dx.doi.org/10.12753/2066-026x-19-179.

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Salmonella is a zoonotic disease that is transmitted from animal products by contact with sick animals or the environments where these animals are living. The mathematical model of transmission disease improve the students' understanding of pathogen dynamics, the role of factors that influence the transmission and control of a specific pathogen and the trend of antimicrobial resistance for this pathogen. The tendency to increase of resistance of Salmonella to antibiotic and combination of antibiotics suggest that models are useful in simulation of different scenarios for dynamic of transmission of this disease. There are two main Salmonella types: Typhimurium serotype and Enteritidis serotype. Both types are included in the software toolbox in a tutorial and interactive manners. The three models of Salmonella compartmental are presented in friendly manner to user with possibility to automatically generation of system equations using built-in templates. Tools that calculate the R0 number and stability analysis are provided as modules in order to evaluate how the experimental data are fit to model or to evaluate the influence of constant coefficients over mathematical model. Because Salmonella typhi bacteria is responsible for a communicable disease, Typhoid fever, an optional module is append to main software in order to give to student the possibility to improve the knowledge with mathematical model of this disease as direct result of a particular bacteria from a larger group of bacteria. The educational software has a friendly GUI (Graphic User Interface) that help student to understand better the dynamic of a specific pathogen modeled by class of larger mathematical models, the compartmental models.
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Hulea, Calin Ioan, Diana Obistioiu, Anca Hulea, and Viorel Herman. "CHARACTERISATION OF THE ANTIMICROBIAL BEHAVIOUR OF ESCHERICHIA COLI AND SALMONELLA SPP. STRAINS ISOLATED FROM PIGS IN THE WESTERN PART OF ROMANIA." In 22nd SGEM International Multidisciplinary Scientific GeoConference 2022. STEF92 Technology, 2022. http://dx.doi.org/10.5593/sgem2022v/6.2/s25.16.

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The present study investigated the antimicrobial behaviour of E. coli and Salmonella spp. strains, isolated from pigs after their weaning age. Antimicrobial testing susceptibility by the Kirby-Bauer method allowed the identification of bacterial strains with multiple antibiotic resistance (58.02% for E. coli isolated strains and 47.27% for Salmonella isolated strains). Thus, it was noted that all 54 strains of E. coli showed resistance to trimethoprim; sulfathiazole with sulfacetamide and sulfabenzamide; sulphametoxazol with trimethoprim; ciprofloxacin and nalidixic acid; more than 95% of the strains were resistant to streptomycin, ampicillin and kanamycin. Over 60% of Salmonella spp. strains were resistant to lincomycin, streptomycin, tetracycline, and flumequine. The lowest bactericidal activity was attributed to lincomycin, 90.90% of the Salmonella isolates being reistant to this antimicrobial. Regarding the sensitivity of E. coli isolated strains, over 85% showed sensitivity to ceftazidime, aztreonam and imipenem. Between 50% - 60% of Salmonella strains were sensitive to gentamicin, cefotaxime, and amikacin, while less than 50% of the isolates were susceptible to the rest of the studied antibiotics.
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Juncu, Olga. "Incidența bacteriilor din genul salmonella. SPP la unele Unități de creștere a puiilor broiler și a găinilor ouătoare." In Scientific and practical conference with international participation: "Management of the genetic fund of animals – problems, solutions, outlooks". Scientific Practical Institute of Biotechnologies in Animal Husbandry and Veterinary Medicine, 2023. http://dx.doi.org/10.61562/mgfa2023.55.

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As a goal of this investigations was to establish the incidence of the circulation of pathogenic serotipes of the Salmonella spp. bacteria in the poultry enterprises specialized in the growth of broiler chickens and in the poultry factories specialized in production of eggs for current consumption. As material for the research were taken samples from the poultry rooms, and equipment, the faecal samples, shoe, surface washes from the equipment and the eggs for current consumption. The isolation and identification of bacteria from the genus Salmonella spp. were performed to the methodology in force at national level. For serotyping of bacteria from the genus Salmonella spp., were used the monovalent O and H sera. The results of bacteriological investigations of faecal samples collected from broiler chickens, demonstrated that the highest index of bacteria of the genus Salmonella spp. at the age of 1-2 days was 2.09±0.18 log CFU/g , with variations to 2.49±0.19 log CFU/g at the age of 20 days and with an increase up to 3.52±0.20 log UFC/g, at the 40 days age of chickens. Simultaneously with the faecal samples, were taken the samples from chicken corpses. The obtained indices demonstrated that the number of conditionally pathogenic microorganisms in the chickens corpses is higher with 2 log units, com-pared to this index obtained from faecal samples of live chickens. Bacteriological research performed at faecal samples of the flocks of laying hens have demonstrated that the index of bacteria of the genus Salmonella spp. at the age of hens of 145-165 days had relatively low variations (0.65±0.16 log CFU/g). At the beginning of the laying period (290-310 days) this index had a parameteres of 0,71±0,08 log CFU/g, but of the end of the laying period (450-470 days), the index had a double increasing and constituted 1.66±0.24* log CFU/g. The mentioned indexes demonstrated that the veterinary sanitary and preventive curative measures undertaken at the poultry units do not fully prevent the risks of contamination with bacteria of the genus Salmonella spp. and still remain an important problem for the health of poultry flocks. Bacteriological investigations confirmed that the index of Salmonella spp. bacteria in broiler flocks constituted 8.6%, with the predominance of serotype Salmonella pullorum gallinarum, and in laying hen flocks this index constituted 4.2%, with the predominance of Salmonella pullorum gallinarum and Salmonella typhimurium serotypes, which presents a risk of contamination both for poultry flocks and for human health.
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Camitz, A., G. Holmquist, A. Ballagi, and S. Rodgers. "HerdChek Salmonella antibody ELISA for the serological monitoring of Salmonella infection in swine." In Fourth International Symposium on the Epidemiology and Control of Salmonella and Other Food Borne Pathogens in Pork. Iowa State University, Digital Press, 2001. http://dx.doi.org/10.31274/safepork-180809-1172.

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Callaway, T., T. Edrington, A. Brabban, E. Kutter, L. Karriker, C. Stahl, L. Wagstrom, et al. "Isolation of Salmonella spp. and bacteriophage active against Salmonella spp. from commercial swine." In First International Symposium on the Ecology of Salmonella in Pork Production. Iowa State University, Digital Press, 2007. http://dx.doi.org/10.31274/safepork-180809-99.

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Espinoza Barrera, D. E., and C. A. Aguilar Lopez. "Necrotizing Pneumonia Secondary to Salmonella." In American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a4498.

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Reports on the topic "Salmonella"

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Mason, John. Effects of conalbumin bound iron on the growth of Salmonella paratyphi B and Salmonella thompson. Portland State University Library, January 2000. http://dx.doi.org/10.15760/etd.6265.

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Olsen, Eric V., Iryna B. Sorokulova, I.-Hsuan Chen, Ben Fiebor, and James M. Barbaree. Landscape Phage Probes for Salmonella Typhimurium. Fort Belvoir, VA: Defense Technical Information Center, January 2004. http://dx.doi.org/10.21236/ada426603.

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Andrews, Paul W., Raymond R. Tice, and Diane Satterfield. Salmonella Typhimurium Microsome Reverse Mutation Assay. Fort Belvoir, VA: Defense Technical Information Center, March 1996. http://dx.doi.org/10.21236/ada589278.

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Petrova, S. G., and M. P. Neustroev. Salmonella abortion of horses (ETIOLOGY, PREVENTION). Yakut State Agricultural Academy, 2019. http://dx.doi.org/10.18411/978-5-6042744-2-2-253-255.

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Brandl, Maria T., Shlomo Sela, Craig T. Parker, and Victor Rodov. Salmonella enterica Interactions with Fresh Produce. United States Department of Agriculture, September 2010. http://dx.doi.org/10.32747/2010.7592642.bard.

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The emergence of food-borne illness outbreaks linked to the contamination of fruits and vegetables is a great concern in industrialized countries. The current lack of control measures and effective sanitization methods prompt the need for new strategies to reduce contamination of produce. Our ability to assess the risk associated with produce contamination and to devise innovative control strategies depends on the identification of critical determinants that affect the growth and the persistence of human pathogens on plants. Salmonella enterica, a common causal agent of illness linked to produce, has the ability to colonize and persist on plants. Thus, our main objective was to identify plant-inducible genes that have a role in the growth and/or persistence of S. enterica on postharvest lettuce. Our findings suggest that in-vitro biofilm formation tests may provide a suitable model to predict the initial attachment of Salmonella to cut-romaine lettuce leaves and confirm that Salmonella could persist on lettuce during shelf-life storage. Importantly, we found that Salmonella association with lettuce increases its acid-tolerance, a trait which might be correlated with an enhanced ability of the pathogen to pass through the acidic barrier of the stomach. We have demonstrated that Salmonella can internalize leaves of iceberg lettuce through open stomata. We found for the first time that internalization is an active bacterial process mediated by chemotaxis and motility toward nutrient produced in the leaf by photosynthesis. These findings may provide a partial explanation for the failure of sanitizers to efficiently eradicate foodborne pathogens in leafy greens and may point to a novel mechanism utilized by foodborne and perhaps plant pathogens to colonize leaves. Using resolvase in vivo expression technology (RIVET) we have managed to identify multiple Salmonella genes, some of which with no assigned function, which are involved in attachment to and persistence of Salmonella on lettuce leaves. The precise function of these genes in Salmonella-leaf interactions is yet to be elucidated. Taken together, our findings have advanced the understanding of how Salmonella persist in the plant environment, as well as the potential consequences upon ingestion by human. The emerging knowledge opens new research directions which should ultimately be useful in developing new strategies and approaches to reduce leaf contamination and enhance the safety of fresh produce.
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Lamont, Susan J., and Massoud Malek. Genes for Resistance to Salmonella in Poultry. Ames (Iowa): Iowa State University, January 2004. http://dx.doi.org/10.31274/ans_air-180814-104.

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Lamont, Susan J., and Jason R. Hasenstein. Genes for Resistance to Salmonella in Poultry. Ames (Iowa): Iowa State University, January 2005. http://dx.doi.org/10.31274/ans_air-180814-1065.

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Sela, Shlomo, and Michael McClelland. Desiccation Tolerance in Salmonella and its Implications. United States Department of Agriculture, May 2013. http://dx.doi.org/10.32747/2013.7594389.bard.

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Salmonella enterica is a worldwide food-borne pathogen, which regularly causes large outbreaks of food poisoning. Recent outbreaks linked to consumption of contaminated foods with low water-activity, have raised interest in understanding the factors that control fitness of this pathogen to dry environment. Consequently, the general objective of this study was to extend our knowledge on desiccation tolerance and long-term persistence of Salmonella. We discovered that dehydrated STm entered into a viable-but-nonculturable state, and that addition of chloramphenicol reduced bacterial survival. This finding implied that adaptation to desiccation stress requires de-novo protein synthesis. We also discovered that dried STm cells develop cross-tolerance to multiple stresses that the pathogen might encounter in the agriculture/food environment, such as high or low temperatures, salt, and various disinfectants. These findings have important implications for food safety because they demonstrate the limitations of chemical and physical treatments currently utilized by the food industry to completely inactivate Salmonella. In order to identify genes involved in desiccation stress tolerance, we employed transcriptomic analysis of dehydrated and wet cells and direct screening of knock-out mutant and transposon libraries. Transcriptomic analysis revealed that dehydration induced expression of ninety genes and down-regulated seven. Ribosomal structural genes represented the most abundant functional group with a relatively higher transcription during dehydration. Other large classes of induced functional groups included genes involved in amino acid metabolism, energy production, ion transport, transcription, and stress response. Initial genetic analysis of a number of up-regulated genes was carried out). It was found that mutations in rpoS, yahO, aceA, nifU, rpoE, ddg,fnr and kdpE significantly compromised desiccation tolerance, supporting their role in desiccation stress response.
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Melotto, M., and S. Sela. NIFA-BARD collaborative, mechanisms of salmonella adaptation to the lettuce phyllosphere. Israel: United States-Israel Binational Agricultural Research and Development Fund, 2022. http://dx.doi.org/10.32747/2022.8134153.bard.

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The goal of this study is to evaluate the risk associated with colonization of the plant with Salmonella and to provide the scientific basis required to reduce plant's colonization by this pathogen through characterization of the molecular and physiological mechanisms that enable Salmonella to colonize vegetable crops
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Lewis, Erin, Victoria Cohen, Charlotte Evans, and Iulia Gherman. Salmonella risk profile of UK-produced hen shell eggs. Food Standards Agency, July 2023. http://dx.doi.org/10.46756/sci.fsa.rpp424.

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A previous risk assessment (Opens in a new window) from the Advisory Committee on the Microbiological Safety of Food (ACMSF) in 2016 concluded that due to the significant reduction in the risk from Salmonella in UK-produced hen shell eggs produced under a recognised farm assurance scheme (Lion Code or equivalent), the risk to consumers from eggs produced under these schemes was ‘very low’. This risk assessment led the FSA and FSS to update their consumer advice on the consumption of eggs in 2017, stating that vulnerable groups could consume raw or runny eggs produced within an assurance scheme. This risk profile will examine the current situation of Salmonella in UK-produced table eggs, and the factors that may influence the current risk of Salmonella in UK-produced eggs and highlight any that have changed since the risk assessment provided by the ACMSF in 2016.
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