Relevant bibliographies by topics / Salivary substitute

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Salivary substitute'

Author: Grafiati
Published: 24 August 2024

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Journal articles on the topic "Salivary substitute"

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Sari, Dina Keumala, Liza Meutia Sari, Lidya Imelda Laksmi, Farhat Farhat, Elvita Rahmi Daulay, Ferry Sandra, Zulfikar Lubis, and Ratna Akbari Ganie. "Serumal and Salivary 25(OH)D and 1,25(OH)D Levels of Head and Neck Cancer Patients." Indonesian Biomedical Journal 13, no. 4 (December 31, 2021): 438–43. http://dx.doi.org/10.18585/inabj.v13i4.1726.

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BACKGROUND: Saliva has been suggested as a substitute of serum for the detection of 25 Dihydroxyvitamin D (25(OH)D) in healthy people. However, investigation of salivary 1,25(OH)D has not been clearly reported. Vitamin plays important roles in inhibiting cancer progression. Current study was conducted to investigate serumal and salivary 25(OH)D) and 1,25(OH)D levels of healthy and head and neck cancer (HNC) subjects.METHODS: Research were conducted at Haji Adam Malik Hospital, Medan, Indonesia. Forty HNC and 40 healthy subjects were recruited and selected based on inclusion and exclusion criteria. Medical records were documented, followed by anthropometric evaluation and serum and saliva collection. Laboratory investigation for 25(OH)D and 1,25(OH) was performed using Enzyme-linked immunosorbent assay (ELISA) methods.RESULTS: Significant serumal (p=0.002) and salivary (p=0.016) 25(OH)D mean level differences of HNC and normal groups were obtained. More serumal or salivary 25(OH)D deficient subjects were found in control group than those in HNC group. Meanwhile, serumal and salivary 1,25(OH)D mean levels of HNC group were not significantly different with the ones of control group. There were significant correlations of serumal-salivary 25(OH)D as well as serumal-salivary 1,25(OH)D levels in normal group.CONCLUSION: Serumal and salivary 25(OH)D and 1,25(OH)D levels of HNC group were relatively normal. Salivary 25(OH)D and 1,25(OH)D could be suggested as substitutes for serumal ones.KEYWORDS: vitamin D, 25(OH)D, 1,25(OH)D, head and neck cancer
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Cokro, Ingrid Aurelia Genacia, Dewi Priandini, Deviyanti Pratiwi, and Akhmad Endang Zainal Hasan. "The effect of trigona spp. Propolis extract to saliva substitute ph as xerostomia therapy." Odonto : Dental Journal 10, no. 1 (July 31, 2023): 117. http://dx.doi.org/10.30659/odj.10.1.117-124.

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Background: Patients with xerostomia generally have an acidic salivary pH. Low oral pH increases the occurrence of tooth caries and development of oral lesions such as recurrent aphthous stomatitis (RAS) which are prone to occur in patients with xerostomia. Trigona spp. propolis extract with antimicrobial compounds was used as an additional natural ingredient in saliva substitute to inhibit the growth of Streptococcus mutans and prevent the decrease of salivary pH in patients with xerostomia. This study aimed to determine the effect of Trigona spp. propolis extract to saliva substitute pH as therapy for xerostomia with antimicrobial activity. Method: This study was experimental laboratory, namely Post-test only Control Group Design. The propolis Trigona spp. extract used in this study was extracted using maceration method with 70% ethanol as solvent which was then diluted into 5 concentrations 1,25%, 2,5%, 5%, 10%, 20%. This study used Streptococcus mutans (ATCC 25175) and saliva substitute with pH of 6.8. The research includes phytochemical test, absorbance measurement and pH test. Result: There is a significant difference in the pH value between saliva substitute induced with Streptococcus mutans with Trigona spp. propolis extract and the control group. Data analysis using One-way ANOVA test showed a significant value of
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Porangaba, Letícia Pacheco, Flávio de Melo Garcia, Ana Paula Alvarenga Antonio Rabelo, Amanda Puche Andrade, Fabio de Abreu Alves, Antonio Cássio Assis Pellizzon, and Graziella Chagas Jaguar. "Randomized Double-Blind Placebo-Controlled Study of Salivary Substitute with Enzymatic System for Xerostomia in Patients Irradiated in Head and Neck Region." Current Oncology 31, no. 2 (February 18, 2024): 1102–12. http://dx.doi.org/10.3390/curroncol31020082.

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This study aims to compare whether the use of a salivary substitute including an enzymatic system clinically reduces the intensity of xerostomia, as well as exploring the impact that this has on the quality of life, in patients who had received radiotherapy in the head and neck (HNC) region. Forty patients who had completed radiotherapy treatment within 6 months to 1 year previously were allocated into an Enzymatic Spray group (n = 21) or a Placebo arm (n = 19). It should be noted that two patients in the Placebo arm declined to participate during phase 2 of the study. All patients were randomized and used both products three times a day for 30 days. For analysis, xerostomia grade, unstimulated (UWS) and stimulated (SWS) salivary flow rate, and quality of life through the University of Washington Quality of Life Questionnaire validated in Portuguese (UW-QoL) were assessed in two phases: Phase 1 (before the use of the products) and Phase 2 (after 30 days of using the products). All clinical data were collected from medical records. Analyzing the salivary substitute with the enzymatic system, an improvement in xerostomia complaints was observed 30 days after using the product; however, this difference was not statistically significant (p > 0.05). Regarding quality of life, no significant differences were observed in relation to the UW-QoL and saliva domain between the groups in the two phases of the study (p > 0.05). The salivary substitute with the enzymatic system may be effective in reducing radio-induced xerostomia symptoms; however, further research is necessary to evaluate the efficacy of this salivary substitute on oral health.
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Sushanthi S, Leelavathi L, Meignana Arumugham Indiran, Pradeep Kumar Rathinavelu, and Rajesh Kumar S. "Assessing the effect of natural sweetener on salivary pH and streptococcus mutans growth- An invivo study." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (December 21, 2020): 7799–804. http://dx.doi.org/10.26452/ijrps.v11i4.3975.

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Stevia is a natural sweetener which is used as a sugar substitute. It has been suggested that Stevia may be anti-cariogenic. However, there is limited research in this regard. Currently, Stevia rebaudiana, a plant is considered to be a suitable replacement of sugar which is healthy and has much fewer side effects than other sweeteners. To assess the salivary pH and streptococcus mutans growth among the participants after mouth rinsing with water containing natural sweetener. This double-blinded parallel clinical trial was done among forty female participants aged 22-25 years. Study participants were selected and randomly allocated by lottery method as two different groups as group A, and B. Microbial growth and pH of the saliva was assessed twice, once before rising with stevia solution and at 20 minutes after rinsing with a sugar solution containing Stevia (single tablet and two tablets) mixed in distilled water. Collected data were analyzed using the paired t-test. It was found from the study that there was an increase in mean salivary pH when compared with the baseline value after rinsing with Stevia. There was an increase in the Streptococcus mutans count after rinsing with Stevia. Increase in streptococcus mutans count was found to be low in Group A than group B. pH value stays in neutral value even after rinsing with a natural sweetener. There is no much difference between Group A and B. Salivary pH after mouth rinsing with Stevia is in a neutral state. It has low Streptococcus mutans growth suggesting that Stevia can also be used as a sugar substitute replacing artificial sugar substitutes.
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Sushanthi S, Leelavathi L, Meignana Arumugham Indiran, Pradeep Kumar Rathinavelu, and Rajesh Kumar S. "Assessing the effect of natural sweetener on salivary pH and streptococcus mutans growth- An invivo study." International Journal of Research in Pharmaceutical Sciences 12, no. 1 (January 6, 2021): 180–85. http://dx.doi.org/10.26452/ijrps.v12i1.3975.

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Stevia is a natural sweetener which is used as a sugar substitute. It has been suggested that Stevia may be anti-cariogenic. However, there is limited research in this regard. Currently, Stevia rebaudiana, a plant is considered to be a suitable replacement of sugar which is healthy and has much fewer side effects than other sweeteners. To assess the salivary pH and streptococcus mutans growth among the participants after mouth rinsing with water containing natural sweetener. This double-blinded parallel clinical trial was done among forty female participants aged 22-25 years. Study participants were selected and randomly allocated by lottery method as two different groups as group A, and B. Microbial growth and pH of the saliva was assessed twice, once before rising with stevia solution and at 20 minutes after rinsing with a sugar solution containing Stevia (single tablet and two tablets) mixed in distilled water. Collected data were analyzed using the paired t-test. It was found from the study that there was an increase in mean salivary pH when compared with the baseline value after rinsing with Stevia. There was an increase in the Streptococcus mutans count after rinsing with Stevia. Increase in streptococcus mutans count was found to be low in Group A than group B. pH value stays in neutral value even after rinsing with a natural sweetener. There is no much difference between Group A and B. Salivary pH after mouth rinsing with Stevia is in a neutral state. It has low Streptococcus mutans growth suggesting that Stevia can also be used as a sugar substitute replacing artificial sugar substitutes.
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Pathania, Neha, Sabat Un Noor, Rahul Kumar, Archana Nagpal, and Rajeev Gupta. "An ingenious technique for functional palatal reservoir construction in complete dentures." IP Annals of Prosthodontics and Restorative Dentistry 7, no. 4 (December 15, 2021): 195–99. http://dx.doi.org/10.18231/j.aprd.2021.039.

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The retention, stability and comfort of wearing denture is greatly influenced by the flow, quantity and consistency of saliva. Insufficient salivary output results especially in old-aged edentulous patients may result in denture sores because of lack of lubrication by saliva, thus, reducing patient’s ability to retain the prosthesis. Various approaches have been concernes with the use of reservoir with holes have been described in the literature. However the flow of salivary substitute is very difficult to control. Moreover the frequent cleaning of the denture required to maintain the patency of the reservoir holes poses various challenges to the patient. This article explains a novel technique for the incorporation of a reservoir with controlled salivary flow in complete denture to enhance the retention of the prosthesis and thus, improving the comfort of wearing denture and the speech of patient.
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Bharanija, K. S., V. Ashok, and Anandapandian Ponsekar Abraham. "An innovative technique for palatal reservoir construction in complete dentures: A case report." Journal of Dental Research, Dental Clinics, Dental Prospects 12, no. 3 (September 26, 2018): 227–31. http://dx.doi.org/10.15171/joddd.2018.035.

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The retention and comfort of wearing prosthesis mainly depends on saliva. In reduced saliva conditions, such as xerostomia or radiation therapy, the oral mucosa tends to become dry and ulcerated, leading to the patient's inability to retain the prosthesis. Various techniques have been reported in the literature regarding the use of a reservoir with holes in dentures. The results have not been satisfactory because the flow of the salivary substitute could not be controlled and with frequent cleaning of the denture being necassary to maintain the patency of the reservoir holes. A newer technique for incorporation of a palatal reservoir with controlled artificial salivary flow in complete denture is being explained in this article, which improved the denture retention, comfort, mastication and speech of the patient.
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Ibarra, M., Marta Vázquez, P. Fagiolino, F. Mutilva, and A. Canale. "Total, unbound plasma and salivary phenytoin levels in critically ill patients." Journal of Epilepsy and Clinical Neurophysiology 16, no. 2 (2010): 69–73. http://dx.doi.org/10.1590/s1676-26492010000200006.

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OBJECTIVE: To assess the reliability of salivary phenytoin (PHT) concentrations and predicted free PHT levels by Sheiner-Tozer equation in order to substitute measured free PHT concentrations in critically ill patients. METHODOLOGY: Twenty-four neurocritically ill adult patients receiving intravenous PHT were included in the study. Analyses of total, free plasma and saliva PHT concentrations were performed by fluorescence polarization immunoassay. Plasma albumin levels were also determined. RESULTS: Free PHT concentrations as well as salivary levels better correlate to clinical effect than total drug concentrations. Linear regression analysis showed a strong correlation between estimated free PHT concentrations by Sheiner-Tozer and measured free PHT levels (r=0.835; p<0.001) and salivary PHT concentrations and measured free PHT concentrations (r=0.964; p<0.001). Sheiner-Tozer equation could be misleading in the presence of displacing drugs. CONCLUSIONS: Saliva may serve as a feasible fluid to plasma in order to be used as a surrogate for free concentration monitoring of PHT in this population.
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Honceriu, Cezar, Mihai Roca, Alexandru Dan Costache, Beatrice Abălașei, Lucian Popescu, Alexandru Rareș Puni, Alexandra Maștaleru, et al. "Blood and Salivary Cortisol Variations in Athletes in Relation to Cardiopulmonary Exercise Testing." Medicina 59, no. 10 (September 27, 2023): 1726. http://dx.doi.org/10.3390/medicina59101726.

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Background and Objectives: Cortisol is a valuable marker for assessing the body’s response to any form of stress. We conducted this study in order to evaluate the variations of salivary and serum cortisol levels in professional football players in relation to cardiopulmonary exercise testing (CPET) and their significance in potentially evaluating overtraining in athletes. Also, the question of whether salivary cortisol determination could fully substitute serum sampling was addressed. Materials and Methods: A total of 19 male professional football players were evaluated by measuring serum cortisol levels at rest (T0) and immediately after a CPET (T1) and salivary cortisol levels at rest (T0), 10 min after a CPET (T2), and 30 min after a CPET (T3). Results: T0 serum cortisol showed a statistically significant correlation with the oxygen uptake at the anaerobic threshold divided by the body weight (VO2-AT/weight), as did the T2 salivary cortisol with the maximum oxygen uptake at the anaerobic threshold (VO2-AT) and VO2-AT/weight. T0 salivary cortisol was significantly correlated with the subjects’ height and the predicted O2 pulse. Conclusions: While some correlations were discovered, they are insufficient to recommend cortisol as a routine biomarker in athletes’ evaluation. However, significant correlations were established between salivary and serum determinations, meaning that the non-invasive procedure could substitute venous blood sampling.
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Sari, Dina Keumala, Liza Meutia Sari, Lidya Imelda Laksmi, and Farhat Farhat. "The Use of 25-hydroxyvitamin D Saliva Test to Replace Vitamin D Serum Blood Test in Healthy People." Open Access Macedonian Journal of Medical Sciences 9, T3 (May 17, 2021): 40–43. http://dx.doi.org/10.3889/oamjms.2021.6329.

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BACKGROUND: Routine examination of Vitamin D levels is carried out by checking serum 25-hydroxyvitamin D (25[OH]D) levels which indicate circulating Vitamin D levels. While serum 1.25(OH)D levels are less frequently performed, although serum 1.25(OH)D levels represent the active form of Vitamin D be a substitute for checking Vitamin D levels. AIMS: This study aims to see the correlation between Vitamin D levels, namely, 25(OH)D and 1.25(OH)D saliva, which correlate with serum 25(OH)D and 1.25(OH)D levels so that the examination of salivary Vitamin D levels can be a substitute for checking serum Vitamin D levels. MATERIAL AND METHODS: This study is a cross-sectional study involving healthy men and women, aged 20–50 years, sampling in Lima Puluh Village, Batubara District, North Sumatra Province, Indonesia. The parameters studied were 25(OH)D and 1.25(OH)D levels of saliva and serum. RESULTS: This study involved 56 study subjects, male and female, with a percentage of deficiencies of 78.6% by examining 25(OH)D saliva and 76.8% by examining 25(OH)D serum. As for the 1.25(OH)D examination of saliva and serum, all were within normal limits. The analysis showed that a moderate correlation was obtained for levels of 25(OH)D saliva with serum 25(OH)D (p = 0.424) and a weak correlation for levels of 1.25(OH)D saliva with serum 25(OH)D (p = 0.339). CONCLUSIONS: Salivary 25(OH)D assay can be used to replace serum 25(OH)D assay in healthy people as a non-invasive alternative.
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Dissertations / Theses on the topic "Salivary substitute"

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Sardinha, Daniela Abreu. "Xerostomia e hipofunção das glândulas salivares: fisiopatologia e enquadramento clínico." Master's thesis, [s.n.], 2013. http://hdl.handle.net/10284/5250.

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Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Medicina Dentária
A saliva desempenha múltiplas funções e tem um papel vital na proteção da saúde dos tecidos moles e duros da cavidade oral. A xerostomia é a sensação subjetiva de boca seca, um sintoma que pode ou não estar acompanhado de hipossalivação, descrita como redução do fluxo salivar estimulado ou não estimulado. Os pacientes com redução do fluxo salivar apresentam maior risco de cáries, infeções fúngicas orais, dificuldades na deglutição e alteração do paladar. As principais causas da hipofunção das glândulas salivares e da xerostomia são doenças sistémicas e os medicamentos. O diagnóstico é baseado em métodos simples, como a medição do fluxo salivar estimulado e não estimulado. Sendo que o tratamento da xerostomia é essencialmente realizado tendo em conta a sua causa e é dividido em quatro categorias: prevenção, tratamento sintomático, estimulação local ou tópica e terapias sistémicas ou estimulação sistémica. Cada categoria será aplicada dependendo da função glandular. Quando há alguma preservação da estrutura da GS os estimulantes salivares (estimulação local ou sistémica) são o mais indicado. Quando as GS encontram-se irreversivelmente danificadas a opção é o tratamento paliativo.
Saliva has multiple functions and plays a vital role in protecting the health of hard and soft tissues of the oral cavity. Xerostomia is the subjective sensation of dry mouth, a symptom that may or may not be accompanied by hyposalivation, described as a reduction of unstimulated and stimulated salivary flow. Patients with reduced salivary flow are at increased risk for caries, oral fungal infections, swallowing problems and altered taste. The principal causes of salivary gland hypofunction and xerostomia are systemic diseases and drugs. The diagnosis is based on simple methods, as measuring both unstimulated and stimulated salivary flow rate. Treatment of xerostomia essentially is carried out in regard to the cause and is divided in four main categories: palliative or symptomatic stimulation, local and systemic stimulation and prevention of complications. Which category will be applied, depending on salivary glands function. In cases when there is still some residual salivary function it was shown that saliva stimulans (local or systemic stimulation) is more appropriate. When salivary glands are irreversible damaged palliative treatment is the best option.
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Bugarin, Castillo Yurixy. "Évaluation instrumentale et sensorielle des produits alimentaires pour la gestion des troubles salivaires et de la déglutition." Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASB023.

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Les troubles de la déglutition sont l'une des principales causes de malnutrition et de déshydratation chez les personnes âgées. Cette étude présente une boîte à outils de méthodes précliniques pour évaluer les produits alimentaires destinés à pallier les symptômes des troubles de la salivation et de la déglutition. Une première illustration de cette approche concerne la conception de substituts salivaires naturels (SSN) et d'aliments semi-liquides à texture adaptée. Différents extraits naturels ont été produits et comparés à la salive humaine en termes de propriétés rhéologiques en cisaillement et en extension, ce qui a permis de sélectionner des formulations naturelles à base d'extraits de graines de lin au fort potentiel. La capacité de ces formulations à limiter les résidus oraux après déglutition a été confirmée à l'aide d'un simulateur de déglutition soft-robotique in vitro et par analyse sensorielle. L'impression 3D alimentaire a été aussi utilisée pour produire des aliments avec aux structures contrôlées afin d'adapter la texture d‘aliments solides. Une gamme intéressante de propriétés mécaniques a été obtenue. Les performances des NSS en matière d'hydratation et de lubrification de ces structures imprimées en 3D ont également été explorées in vitro.Cette étude démontre i) la pertinence de ces ou-tils précliniques, y compris les expériences in vitro simulant différents aspects de la transformation orale des aliments, pour faciliter le développement de produits alimentaires personnalisés et aliments destinés à des fins médicales spéciales ii) le fort potentiel des extraits de graines de lin comme SSN ou agent texturant, grâce à leurs propriétés rhéologiques et pouvoir lubrifiant et iii) l'intérêt de contrôler la structure des aliments par impression 3D, pour moduler leurs propriétés mécaniques et leur hydratation
Swallowing disorders, also known as dysphagia, are a leading cause of malnutrition and dehydration for older people. In this study, a toolbox of preclinical methods is developed to evaluate food products to manage swallowing disorders and xerostomia, the dry mouth sensation induced by the alteration of salivary flow rate.As a first illustration of the use of these preclinical tools, different natural extracts were produced and compared to human saliva, in terms of both shear and extensional rheological properties. The most promising formulations, obtained from flaxseed extracts, were used to formulate natural salivary substitutes (NSS) and texture adapted semi liquid foods, to promote lubrication and address the needs of people suffering from xerostomia. In addition, the ability of NSSs and modified semi liquid foods to limit post-swallowing oral residues was determined with an in vitro soft-robotic swallowing simulator and con-firmed by sensory analysis on healthy subjects.Three-dimensional printing was used to produce foods with controlled structures, resulting in different yielding behaviors, paving the way to texture adaptation to manage sarcopenia. NSS performance in terms of hydration and lubrication of these 3D-printed structures was also explored, in vitro.This study highlights i) the relevance of this pre-clinical toolbox, including the in vitro experiments simulating food oral processing, to support the development of personalized food products and food for special medical purposes ii) the peculiar rheological properties and lubricity of flaxseed ex-tracts and their strong potential as a NSS or texture modifier, and iii) the interest of controlling food structure via 3D printing to modulate food hydration and the mechanical and yielding behavior
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Tschoppe, Peter [Verfasser]. "Development of a remineralizing saliva substitute and effects of various saliva substitutes in combination with fluorides on enamel and dentin / Peter Tschoppe." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2011. http://d-nb.info/1026265487/34.

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Peng, Jingyuan, and 彭靖园. "Morphological and quantitative analysis of silver compounds on demineralised dentine in saliva substitutes." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/197082.

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Silver compounds have become popular for the treatment of arresting dental caries and dentine hypersensitivity. This study investigated the interaction of silver compounds in demineralised dentine under different conditions. Scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDX), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), ion chromatography (IC) and inductively coupled plasma-mass spectroscopy (ICP-MS) were used to analyse these interactions. A systematically-approached literature review was conducted on silver compounds in dentistry. They have been demonstrated to be effective for preventing and arresting caries, as well dentine desensitivity. The mode of action of silver compounds on carious teeth includes inhibition of demineralisation process and anti-bacterial effect. Reaction products of Silver Diammine Fluoride (SDF) on dentine in different saliva substitutes were determined. Dentine samples were stored in deionised water (DIW), non-protein artificial saliva (NPAS), basal medium mucin (BMM), and un-stimulated whole saliva (UWS). These samples were chemically demineralised. Afterwards 38 wt-% SDF was applied. Dentine surfaces were analysed by SEM and showed different surface deposits and coatings. EDX, XPS and XRD detected metallic silver and silver compounds (predominantly AgCl) were formed and the amount was highest in NPAS group. BMM and UWS groups showed similar reactions. Sulphur was detected only in BMM and UWS groups. Chemical composition of BMM and UWS were determined by IC. Dentine samples were pre-saturated with BMM, UWS and DIW and then chemically demineralised. Either of 42 wt-% AgNO3, 22 wt-% AgF and 38 wt-% SDF was applied. Treated samples were replaced in their respective “saliva”. The exposed surface and a cross-section of dentine was analysed by quantitative EDX. A precise linear relation of the silver standard wires (wt-%) according to EDX counts was obtained (R2 > 0.99). The amount of silver was concentrated between 0 to 60 μm in depth. BMM groups yielded the highest amount of silver for AgF and AgNO3 compounds (p < 0.06), which may be related to the greater concentration of salivary protein and chloride in BMM solution. ICP-MS was used to quantitatively determine silver present on SDF-treated dentine. Dentine samples were pre-saturated with BMM or UWS and chemically demineralised. Afterwards 10 wt-%, 24 wt-% or 38 wt-% of SDF was applied and the treated samples were re-placed with respective “saliva” daily for 5 days. Dentine samples were then digested in 70% HNO3 and silver concentration was determined by ICP. For UWS, silver was in proportion to the application of various concentrations of SDF. However, for BMM, the higher amount of silver at 10 wt-% and 38 wt-% SDF suggests an interaction effect with excessive salivary protein and chloride. Reaction products of silver compounds on dentine can be determined by the combined SEM-EDX, XPS and XRD techniques. Both modified SEM-EDX and ICP techniques are qualified for quantitative comparison of silver concentration between treatment groups. The interaction effects of silver with different in vitro salivary components should be considered in future investigations as this may affect the chemical reaction outcomes.
published_or_final_version
Dentistry
Doctoral
Doctor of Philosophy
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Lochner, Johann Georg. "A comparison of two saliva substitutes in the management of xerostomia during radiotherapy for cancer of the head and neck." Thesis, University of the Western Cape, 2007. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_9540_1257166768.

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The aim of the study is to compare the palliative efficacy of two saliva substitutes (Sinspeek and Xerostom) in patients during radiotherapy for cancer of the head and neck. This crossover randomised controlled clinical trial was carried out on twenty-five patients with malignant tumours of the head and neck, following four weeks of radiotherapy at tygerberg hospital. The benefit of saliva substitutes to ameliorate the effects of xerostomia is well established and proper advice and access to relevant preparations is essential.

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Zandim, Daniela Leal [Verfasser]. "The effect of daily fluoride applications in combination with saliva substitutes on remineralization of bovine dentin and enamel subsurface lesions / Daniela Leal Zandim." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2011. http://d-nb.info/1026068908/34.

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Thomas, Yohan John. "An in vitro study of the effect of natural alternative saliva substitutes on enamel wear / Yohan John Thomas." Thesis, 2006. http://hdl.handle.net/2440/38198.

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"December 2006"
Coursework
Research report submitted in partial fulfillment of the requirements for the Graduate Diploma in Clinical Dentistry, October 2002
With: "Research report: Salivary substitutes: home-based production" : in the back section of the volume.
Bibliography: leaves 74-84.
92 leaves, 45 :
Title page, contents and abstract only. The complete thesis in print form is available from the University Library.
Thesis (D.Clin.Dent.)--University of Adelaide, School of Dentistry, 2006
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Thomas, Yohan John. "An in vitro study of the effect of natural alternative saliva substitutes on enamel wear / Yohan John Thomas." 2006. http://hdl.handle.net/2440/38198.

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"December 2006"
Coursework
Research report submitted in partial fulfillment of the requirements for the Graduate Diploma in Clinical Dentistry, October 2002
With: "Research report: Salivary substitutes: home-based production" : in the back section of the volume.
Bibliography: leaves 74-84.
92 leaves, 45 :
Title page, contents and abstract only. The complete thesis in print form is available from the University Library.
Thesis (D.Clin.Dent.)--University of Adelaide, School of Dentistry, 2006
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Book chapters on the topic "Salivary substitute"

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Mellema, J., H. J. Holterman, E. J. s-Gravenmade, H. A. Waterman, and C. Blom. "Rheology of Human Saliva and Saliva Substitutes." In Third European Rheology Conference and Golden Jubilee Meeting of the British Society of Rheology, 352–54. Dordrecht: Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-009-0781-2_122.

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Sankar, Vidya. "Management of Dry Mouth in Sjögren’s." In The Sjögren's Book, 249–58. Oxford University Press, 2022. http://dx.doi.org/10.1093/oso/9780197502112.003.0024.

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Salivary dysfunction and a feeling of dryness of the mouth (xerostomia) are common characteristics in patients with Sjögren’s. Saliva serves many functions, and salivary dysfunction is associated with an increased risk of dental caries as well as a host of difficulties with the protective features of the oral cavity. Symptomatic and supportive care should include good oral hygiene, proper dietary control, and the use of saliva substitutes, fluoride, and a sialogogue. This chapter will review the role of saliva and treatments that are currently available and discusses ways to maximize the potential benefit of products the patients is either currently using or may have given up on due to improper use or understanding of what the product is intended to do.
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Dias, AJ, C. Baptista, and AL Baltazar. "MIRACULINA: UM ADOÇANTE NATURAL." In Open Science Research X, 527–35. Editora Científica Digital, 2023. http://dx.doi.org/10.37885/230211895.

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RESUMOIntrodução: A elevada ingestão de açúcar é o principal fator associado ao aporte energético excessivo e ao desenvolvimento de obesidade e várias doenças crónicas, nomeadamente diabetes tipo 2 e doenças cardiovasculares. Deste modo, a procura por adoçantes alternativos, não artificiais, tem vindo a aumentar. Um destes é a miraculina, proteína modificadora do sabor encontrada no fruto da fruteira milagrosa (Synsepalum dulcificum).Objetivo: Estudar a miraculina e as suas propriedades nutricionais enquanto adoçante natural.Metodologia: Foi feita uma pesquisa nas bases de dados PubMed e ScienceDirect, com a palavra-chave miraculina e num intervalo temporal de dez anos, da qual resultaram sessenta e nove artigos (1 e sessenta e oito, respetivamente). Após a leitura do título, foram selecionados trinta e seis artigos, dos quais, após leitura do abstract, vinte e seis foram selecionados para leitura integral, tendo estes sido utilizados na elaboração do artigo.Resultados: A miraculina atua nas membranas celulares do sabor, próximo ao local do receptor doce, produzindo a sensação doce. O seu efeito consiste na conversão de sabores azedos em doces, tendo um perfil sensorial semelhante ao da sucralose, substituto do açúcar consagrado e reconhecido, e dura até que seja diluída e eliminada pela saliva. A sua ação depende do pH e da temperatura, sendo diminuída em pH alto e muito diminuída em pH acima de doze ou abaixo de 2,5 e a temperaturas elevadas. Conclusão: A miraculina possui qualidade nutricional e ações farmacológicas, aparentando ser um bom substituto do açúcar em bebidas ácidas. Ainda são necessários estudos futuros em outros produtos que avaliem a perceção do consumidor.
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Conference papers on the topic "Salivary substitute"

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Lysik, Dawid, Robert Bucki, Katarzyna Niemirowicz-Laskowska, and Joanna Mystkowska. "Antimicrobial properties of mucin-based saliva substitute containing xylitol." In 2020 Mechatronics Systems and Materials (MSM). IEEE, 2020. http://dx.doi.org/10.1109/msm49833.2020.9201617.

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Ganesh, R., R. Baier, and A. Meyer. "Tissue-on-tissue lubricity studies of saliva substitutes as-supplied, mixed with and compared with human saliva from control and xerostomia patients." In 2010 36th Annual Northeast Bioengineering Conference. IEEE, 2010. http://dx.doi.org/10.1109/nebc.2010.5458239.

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