Academic literature on the topic 'Saligenin'

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Journal articles on the topic "Saligenin"

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Bakker, Daniël J., Arghya Dey, Daniel P. Tabor, Qin Ong, Jérôme Mahé, Marie-Pierre Gaigeot, Edwin L. Sibert, and Anouk M. Rijs. "Fingerprints of inter- and intramolecular hydrogen bonding in saligenin–water clusters revealed by mid- and far-infrared spectroscopy." Physical Chemistry Chemical Physics 19, no. 31 (2017): 20343–56. http://dx.doi.org/10.1039/c7cp01951c.

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Saragi, Rizalina Tama, Marcos Juanes, José Luis Abad, Alberto Lesarri, Ruth Pinacho, and José Emiliano Rubio. "Rotational spectroscopy of organophosphorous chemical agents: cresyl and phenyl saligenin phosphates." Physical Chemistry Chemical Physics 21, no. 30 (2019): 16418–22. http://dx.doi.org/10.1039/c9cp03093j.

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Cresyl and phenyl saligenin phosphate have been probed in a jet expansion by broadband chirp-excitation microwave spectroscopy, revealing the most stable confirmations and their structural properties.
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Glynn, P., D. J. Read, R. Guo, S. Wylie, and M. K. Johnson. "Synthesis and characterization of a biotinylated organophosphorus ester for detection and affinity purification of a brain serine esterase: neuropathy target esterase." Biochemical Journal 301, no. 2 (July 15, 1994): 551–56. http://dx.doi.org/10.1042/bj3010551.

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We have synthesized a novel stable precursor, saligenin phosphorotrichloridate, which, on reaction with N-monobiotinyldiamines, generates a series of biotinylated covalent inhibitors of serine esterases. A homologue designated S9B [1-(saligenin cyclic phospho)-9-biotinyldiaminononane] was selected to allow detection and rapid isolation of neuropathy target esterase (NTE). This enzyme is the primary target site for those organophosphorus esters (OPs) which cause delayed neuropathy. NTE comprises about 0.03% of the total protein in brain microsomal fractions and has resisted purification attempts over many years. S9B is a potent progressive inhibitor of NTE esteratic activity (second-order rate constant 1.4 x 10(7) M-1.min-1). Incubation of S9B with brain microsomes led to specific covalent labelling of NTE as determined by detection of a biotinylated 155 kDa polypeptide on Western blots. Specificity of S9B labelling was further demonstrated by inhibition with the neuropathic OP mipafox. Biotinyl-NTE in SDS-solubilized S9B-labelled microsomes was adsorbed on to avidin-Sepharose and subsequently eluted, yielding a fraction enriched approx. 1000-fold in NTE by a single step with recoveries of 30%. Essentially pure NTE was obtained after separation from two endogenous biotinylated polypeptides (120 and 70 kDa) in avidin-Sepharose eluates by preparative SDS/PAGE. Other biotinylated saligenin phosphoramidates derived from the same precursor may be useful for detection and isolation of other serine esterases and proteinases.
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Singh, Vishwakarma, Punitha Vedantham, and Pramod K. Sahu. "A novel stereoselective total synthesis of (±)-hirsutene from saligenin." Tetrahedron Letters 43, no. 3 (January 2002): 519–22. http://dx.doi.org/10.1016/s0040-4039(01)02183-9.

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Lushchekina, S. V., V. S. Polomskikh, S. D. Varfolomeev, and P. Masson. "Molecular modeling of butyrylcholinesterase inhibition by cresyl saligenin phosphate." Russian Chemical Bulletin 62, no. 11 (November 2013): 2527–37. http://dx.doi.org/10.1007/s11172-013-0366-9.

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Shiotsuki, Takahiro, Takeshi Kakimoto, and Morifusa Eto. "Irreversible inactivation of glutathione transferases by saligenin cyclic phosphates." Pesticide Biochemistry and Physiology 42, no. 2 (February 1992): 119–27. http://dx.doi.org/10.1016/0048-3575(92)90059-9.

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SHIOTSUKI, Takahiro. "Mode of Action of Saligenin Cyclic Phosphates on Organophosphate-Resistant Houseflies." Journal of Pesticide Science 16, no. 3 (1991): 523–31. http://dx.doi.org/10.1584/jpestics.16.523.

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Lidsky, T. I., C. Manetto, and M. Ehrich. "Nerve conduction studies in chickens given phenyl saligenin phosphate and corticosterone." Journal of Toxicology and Environmental Health 29, no. 1 (January 1990): 65–75. http://dx.doi.org/10.1080/15287399009531372.

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Torgul, M., M. SÜnkÜr, F. B. Kaynak, H. HosgOren, and S. Ozbey. "Saligenin derivative borocryptands: synthesis and structural analysis of new type lithium borocryptate." Journal of Chemical Research (Miniprint) 2003, no. 10 (October 1, 2003): 605. http://dx.doi.org/10.3184/030823503322655670.

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Togrul, M., M. SÜnkÜr, F. B. Kaynak, H. HosgOren, and S. Ozbey. "Saligenin derivative borocryptands: synthesis and structural analysis of new type lithium borocryptate." Journal of Chemical Research 2003, no. 10 (October 1, 2003): 605. http://dx.doi.org/10.3184/030823403322655770.

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Dissertations / Theses on the topic "Saligenin"

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Roy, Probir Kumar. "Studies on some organophosphorus compunds having pesticidal activities (chloro saligenin cyclic phosphoramidothionates." Thesis, University of North Bengal, 1989. http://hdl.handle.net/123456789/1133.

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Guha, Sharmila. "Studies on (i) insecticidal, toxicological and other biological properties of some saligenin cyclic phosphorus compounds, and (ii) cytological effects of some pesticides on plants and animals." Thesis, University of North Bengal, 1992. http://hdl.handle.net/123456789/1027.

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Fox, Jonathan Howard. "Spinal cord gene expression changes in the chicken (Gallus gallus) model of phenyl saligenin phosphate induced delayed neurotoxicity." Diss., Virginia Tech, 2002. http://hdl.handle.net/10919/27192.

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Some organophosphorus (OP) esters induce a central-peripheral distal axonopathy called organophosphorus ester-induced delayed neurotoxicity (OPIDN). In the chicken model neurological deficits and microscopic lesions develop 7-21 days after exposure. Neurotoxic esterase (NTE) is thought to be the initial target in OPIDN. Evidence indicates that neuropathic OP esters have to bind NTE and chemically ?age? for OPIDN induction. It was hypothesized that phenyl saligenin phosphate (PSP), a neuropathic OP ester that essentially irreversibly inhibits NTE as it undergoes the chemical aging process, results in changes in spinal cord gene expression that do not occur with phenylmethylsulfonyl fluoride (PMSF), a non-neuropathic compound that inhibits NTE without aging. This hypothesis was tested in Gallus gallus in experiments designed to detect differences in spinal cord gene expression between PSP, PMSF and vehicle-treated birds 24 hours after exposure. Two approaches were used. Targeted display was developed and used to screen approximately 15000 gel bands. Three candidate genes were identified by targeted display. One, designated P1 has 100% homology with expressed sequence tag pgp1n.pk010.m23, another, P2, is homologous to human KIAA1307, and a third, P3, is unidentified. Northern blotting was used to measure spinal cord expression of a-tubulin and other genes previously reported to be differentially expressed following exposure to di-isopropryl phosphorofluoridate, another agent causing OPIDN. Only expression of a-tubulin was altered in PSP-treated hens. Time course experiments were undertaken to determine spinal cord expression changes of P1, P2, P3 and a-tubulin transcripts at 12, 24, 36 and 48 hours post-exposure. Findings indicated decreases and increases, respectively, of P1 (22%, p=0.0011) and P2 (26%, p=0.0055) transcripts at 12 hours in PSP treated hen spinal cord compared to DMSO controls. An ~2.5 kb a-tubulin transcript was decreased across most time points with maximum change at 48 hours (33%, p=0.0479); an ~4.5 kb a-tubulin transcript was upregulated at 12 hours (38%, p=0.0125) and down regulated at 48 hours (28%, p=0.0576). Responses to PMSF were different than responses to PSP. Spinal cord in-situ hybridization experiments revealed, 1.) mainly neuronal expression of P1, P2 and a-tubulin transcripts, and, 2.) decreased expression of neuronal P1 and a-tubulin transcripts at 12 and 48 hours, respectively. Results indicate that PSP can induce changes in gene expression distinct from those induced with the non-neuropathic NTE inhibitor, PMSF. However, expression changes were low in frequency and magnitude, and their mechanistic importance remains to be fully established.
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Samad, Abdul. "Studies on (i) fungicidal and toxicological properties of saligen in cyclic phosphoramido thionates, and (ii) toxicological effects of some pesticides on Algae." Thesis, University of North Bengal, 1988. http://hdl.handle.net/123456789/1035.

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Books on the topic "Saligenin"

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Duschl, Florian, Ann W. Rea, Tine Ostheimer, and Juliane Schneeweiss. Magisches Mondlicht: Saligen Saga - Band 1. Independently Published, 2018.

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Book chapters on the topic "Saligenin"

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"saligenin, n." In Oxford English Dictionary. 3rd ed. Oxford University Press, 2023. http://dx.doi.org/10.1093/oed/8189689555.

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