Journal articles on the topic 'RUNX2'
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Pulikkan, John Anto, Xue Liting, Rachel Gerstein, Merav Socolovsky, and Lucio H. Castilla. "Deletion Of Core Binding Factors Runx1 and Runx2 Leads To Perturbed Hematopoiesis In Multiple Lineages." Blood 122, no. 21 (November 15, 2013): 46. http://dx.doi.org/10.1182/blood.v122.21.46.46.
Full textEstecio, Marcos R., Sirisha Maddipoti, Courtney D. DiNardo, Hui Yang, William S. Stevenson, Carlos E. Bueso-Ramos, Sherry R. Pierce, Yue Wei, and Guillermo Garcia-Manero. "Association Between RUNX3 Hypermethylation and Acute Myeloid Leukemia Inv(16) Subtype." Blood 124, no. 21 (December 6, 2014): 3548. http://dx.doi.org/10.1182/blood.v124.21.3548.3548.
Full textMorita, Ken, Kensho Suzuki, Shintaro Maeda, Yoshihide Mitsuda, Ayaka Yano, Yoshimi Yamada, Hiroki Kiyose, et al. "Cluster Regulation of RUNX Family By "Gene Switch" Triggers a Profound Tumor Regression of Diverse Origins." Blood 128, no. 22 (December 2, 2016): 443. http://dx.doi.org/10.1182/blood.v128.22.443.443.
Full textZhao, Ling, Jennifer L. Cannons, Lucio H. Castilla, Pamela L. Schwartzberg, and Pu Paul Liu. "The Role of CBFβ in T Cell Development." Blood 104, no. 11 (November 16, 2004): 3234. http://dx.doi.org/10.1182/blood.v104.11.3234.3234.
Full textZhao, Yangli, Tingjuan Zhang, Yangjing Zhao, and Jingdong Zhou. "Distinct association of RUNX family expression with genetic alterations and clinical outcome in acute myeloid leukemia." Cancer Biomarkers 29, no. 3 (October 28, 2020): 387–97. http://dx.doi.org/10.3233/cbm-200016.
Full textMaddipoti, Sirisha C., Carlos Bueso-Ramos, Hui Yang, Michael Fernandez, Shaoquing Kuang, Zihong Fang, William Stevenson, Yue Wei, Sherry Pierce, and Guillermo Garcia-Manero. "Epigenetic Silencing of the RUNX3 Gene by Promoter Hypermethylation in Patients with Acute Myeloid Leukemia." Blood 112, no. 11 (November 16, 2008): 3341. http://dx.doi.org/10.1182/blood.v112.11.3341.3341.
Full textCheng, Chi Keung, Libby Li, Suk Hang Cheng, Kin Mang Lau, Natalie P. H. Chan, Raymond S. M. Wong, Matthew M. K. Shing, Chi Kong Li, and Margaret H. L. Ng. "Transcriptional repression of the RUNX3/AML2 gene by the t(8;21) and inv(16) fusion proteins in acute myeloid leukemia." Blood 112, no. 8 (October 15, 2008): 3391–402. http://dx.doi.org/10.1182/blood-2008-02-137083.
Full textde Bruijn, Marella, and Elaine Dzierzak. "Runx transcription factors in the development and function of the definitive hematopoietic system." Blood 129, no. 15 (April 13, 2017): 2061–69. http://dx.doi.org/10.1182/blood-2016-12-689109.
Full textMcKillop, Anne Jane, Joanne Edwards, Emma Johnson, Susan Mason, Ewan R. Cameron, and Karen Blyth. "Investigating RUNX1 and RUNX2 in prostate cancer." Journal of Clinical Oncology 35, no. 6_suppl (February 20, 2017): 232. http://dx.doi.org/10.1200/jco.2017.35.6_suppl.232.
Full textWang, X. P., T. Åberg, M. J. James, D. Levanon, Y. Groner, and I. Thesleff. "Runx2 (Cbfa1) Inhibits Shh Signaling in the Lower but not Upper Molars of Mouse Embryos and Prevents the Budding of Putative Successional Teeth." Journal of Dental Research 84, no. 2 (February 2005): 138–43. http://dx.doi.org/10.1177/154405910508400206.
Full textSuzuki, Kensho, Ken Morita, Shintaro Maeda, Hiroki Kiyose, Souichi Adachi, and Yasuhiko Kamikubo. "Paradoxical Enhancement of Leukemogenesis in Acute Myeloid Leukemia Cells with Moderately Attenuated RUNX1 Expressions." Blood 128, no. 22 (December 2, 2016): 2710. http://dx.doi.org/10.1182/blood.v128.22.2710.2710.
Full textTang, Chen-Yi, Mengrui Wu, Dongfeng Zhao, Diep Edwards, Abigail McVicar, Yuan Luo, Guochun Zhu, et al. "Runx1 is a central regulator of osteogenesis for bone homeostasis by orchestrating BMP and WNT signaling pathways." PLOS Genetics 17, no. 1 (January 21, 2021): e1009233. http://dx.doi.org/10.1371/journal.pgen.1009233.
Full textJiang, Qing, Xin Qin, Kenichi Nagano, Hisato Komori, Yuki Matsuo, Ichiro Taniuchi, Kosei Ito, and Toshihisa Komori. "Different Requirements of CBFB and RUNX2 in Skeletal Development Among Calvaria, Limbs, Vertebrae and Ribs." International Journal of Molecular Sciences 23, no. 21 (October 31, 2022): 13299. http://dx.doi.org/10.3390/ijms232113299.
Full textLi, Weiping, Shujuan Xu, Shuang Lin, and Wei Zhao. "Overexpression of Runt-Related Transcription Factor-2 Is Associated with Advanced Tumor Progression and Poor Prognosis in Epithelial Ovarian Cancer." Journal of Biomedicine and Biotechnology 2012 (2012): 1–7. http://dx.doi.org/10.1155/2012/456534.
Full textNam, Seunghee, Yun-Hye Jin, Qing-Lin Li, Kwang-Youl Lee, Goo-Bo Jeong, Yoshiaki Ito, Junho Lee, and Suk-Chul Bae. "Expression Pattern, Regulation, and Biological Role of Runt Domain Transcription Factor, run, in Caenorhabditis elegans." Molecular and Cellular Biology 22, no. 2 (January 15, 2002): 547–54. http://dx.doi.org/10.1128/mcb.22.2.547-554.2002.
Full textTang, Jun, Jing Xie, Wei Chen, Chenyi Tang, Jinjin Wu, Yiping Wang, Xue-Dong Zhou, Hou-De Zhou, and Yi-Ping Li. "Runt-related transcription factor 1 is required for murine osteoblast differentiation and bone formation." Journal of Biological Chemistry 295, no. 33 (June 22, 2020): 11669–81. http://dx.doi.org/10.1074/jbc.ra119.007896.
Full textHass, Matthew R., Daniel Brissette, Sreeja Parameswaran, Mario Pujato, Omer Donmez, Leah C. Kottyan, Matthew T. Weirauch, and Raphael Kopan. "Runx1 shapes the chromatin landscape via a cascade of direct and indirect targets." PLOS Genetics 17, no. 6 (June 10, 2021): e1009574. http://dx.doi.org/10.1371/journal.pgen.1009574.
Full textKimura, A., H. Inose, F. Yano, K. Fujita, T. Ikeda, S. Sato, M. Iwasaki, et al. "Runx1 and Runx2 cooperate during sternal morphogenesis." Development 137, no. 7 (February 24, 2010): 1159–67. http://dx.doi.org/10.1242/dev.045005.
Full textInman, Claire K., Na Li, and Paul Shore. "Oct-1 Counteracts Autoinhibition of Runx2 DNA Binding To Form a Novel Runx2/Oct-1 Complex on the Promoter of the Mammary Gland-Specific Gene β-casein." Molecular and Cellular Biology 25, no. 8 (April 15, 2005): 3182–93. http://dx.doi.org/10.1128/mcb.25.8.3182-3193.2005.
Full textFukushima-Nakase, Yoko, Yoshinori Naoe, Ichiro Taniuchi, Hajime Hosoi, Tohru Sugimoto, and Tsukasa Okuda. "Shared and distinct roles mediated through C-terminal subdomains of acute myeloid leukemia/Runt-related transcription factor molecules in murine development." Blood 105, no. 11 (June 1, 2005): 4298–307. http://dx.doi.org/10.1182/blood-2004-08-3372.
Full textOzaki, Toshinori, Akira Nakagawara, and Hiroki Nagase. "RUNX Family Participates in the Regulation of p53-Dependent DNA Damage Response." International Journal of Genomics 2013 (2013): 1–12. http://dx.doi.org/10.1155/2013/271347.
Full textLiu, Jing, Eun-Sil Park, Thomas E. Curry, and Misung Jo. "Periovulatory Expression of Hyaluronan and Proteoglycan Link Protein 1 (Hapln1) in the Rat Ovary: Hormonal Regulation and Potential Function." Endocrine Reviews 31, no. 2 (April 1, 2010): 262–63. http://dx.doi.org/10.1210/edrv.31.2.9997.
Full textMartin, J. W., M. Zielenska, G. S. Stein, A. J. van Wijnen, and J. A. Squire. "The Role of RUNX2 in Osteosarcoma Oncogenesis." Sarcoma 2011 (2011): 1–13. http://dx.doi.org/10.1155/2011/282745.
Full textGoyama, Susumu, Yuko Yamaguchi, Yoichi Imai, Masahito Kawazu, Masahiro Nakagawa, Takashi Asai, Keiki Kumano, et al. "The transcriptionally active form of AML1 is required for hematopoietic rescue of the AML1-deficient embryonic para-aortic splanchnopleural (P-Sp) region." Blood 104, no. 12 (December 1, 2004): 3558–64. http://dx.doi.org/10.1182/blood-2004-04-1535.
Full textGoyama, Susumu, Janet Schibler, Yalan Rao, Mark Wunderlich, Kevin A. Link, Gang Huang, and James C. Mulloy. "Pro-Survival Role of RUNX1 in Acute Myeloid Leukemia with Common Fusion Proteins." Blood 118, no. 21 (November 18, 2011): 870. http://dx.doi.org/10.1182/blood.v118.21.870.870.
Full textKimura, A., F. Yano, H. Inose, K. Fujita, H. Kawaguchi, U. Chung, K. Shinomiya, and S. Takeda. "Cooperative induction of chondrocyte differentiation by Runx1 and Runx2." Bone 44 (May 2009): S150. http://dx.doi.org/10.1016/j.bone.2009.01.329.
Full textYoshida, C. A. "Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog." Genes & Development 18, no. 8 (April 15, 2004): 952–63. http://dx.doi.org/10.1101/gad.1174704.
Full textUkkat, Jörg, Cuong Hoang-Vu, Bogusz Trojanowicz, and Artur Rebelo. "Osteocalcin, Osteopontin and RUNX2 Expression in Patients’ Leucocytes with Arteriosclerosis." Diseases 9, no. 1 (March 12, 2021): 19. http://dx.doi.org/10.3390/diseases9010019.
Full textGreives, Matthew R., Eric A. Odessey, Darrel J. Waggoner, Deana S. Shenaq, Swaroop Aradhya, Allison Mitchell, Emma Whitcomb, Neil Warshawsky, Tong-Chuan He, and Russell R. Reid. "RUNX2 Quadruplication." Journal of Craniofacial Surgery 24, no. 1 (January 2013): 126–29. http://dx.doi.org/10.1097/scs.0b013e31826686d3.
Full textEhrhardt, Götz R. A., Atsushi Hijikata, Hiroshi Kitamura, Osamu Ohara, Ji-Yang Wang, and Max D. Cooper. "Discriminating gene expression profiles of memory B cell subpopulations." Journal of Experimental Medicine 205, no. 8 (July 14, 2008): 1807–17. http://dx.doi.org/10.1084/jem.20072682.
Full textStewart, Monica, Nancy MacKay, Ewan R. Cameron, and James C. Neil. "The Common Retroviral Insertion Locus Dsi1 Maps 30 Kilobases Upstream of the P1 Promoter of the Murine Runx3/Cbfa3/Aml2 Gene." Journal of Virology 76, no. 9 (May 1, 2002): 4364–69. http://dx.doi.org/10.1128/jvi.76.9.4364-4369.2002.
Full textTalebian, Laleh, Zhe Li, Torrey L. Gallagher, Yalin Guo, Caroline L. Speck, Terryl Stacy, and Nancy A. Speck. "A Hypomorphic Cbfb Allele Reveals Requirements for the Development of T Lymphocytes, Granulocytes, and Monocytes/Macrophages, and for Maintaining Proper Numbers of Hematopoietic Progenitors." Blood 104, no. 11 (November 16, 2004): 1596. http://dx.doi.org/10.1182/blood.v104.11.1596.1596.
Full textKanto, Satoru, Marcin Grynberg, Yoshiyuki Kaneko, Jun Fujita, and Masanobu Satake. "A variant of Runx2 that differs from the bone isoform in its splicing is expressed in spermatogenic cells." PeerJ 4 (April 4, 2016): e1862. http://dx.doi.org/10.7717/peerj.1862.
Full textMatheny, Christina J., Takeshi Corpora, Maren E. Speck, Ting-Lei Gu, John H. Bushweller, and Nancy A. Speck. "Biochemical and In Vivo Characterization of Amino Acid Substitutions in the Runx1 (AML1) Runt Domain Found in FPD/AML, AML M0, and Cleidocranial Dysplasia (CCD) Patients." Blood 104, no. 11 (November 16, 2004): 464. http://dx.doi.org/10.1182/blood.v104.11.464.464.
Full textvan der Deen, Margaretha, Hanna Taipaleenmäki, Ying Zhang, Nadiya M. Teplyuk, Anurag Gupta, Senthilkumar Cinghu, Kristen Shogren, et al. "MicroRNA-34c Inversely Couples the Biological Functions of the Runt-related Transcription Factor RUNX2 and the Tumor Suppressor p53 in Osteosarcoma." Journal of Biological Chemistry 288, no. 29 (May 29, 2013): 21307–19. http://dx.doi.org/10.1074/jbc.m112.445890.
Full textKuo, Ya-Huei, Susan Heilman, Amy Chen, Pu P. Liu, Rachel Gernstein, Scott Kogan, and Lucio H. Castilla. "Cbfb-MYH11 Induces Expansion of a Lin-Kit+Sca1- Abnormal Progenitor Compartment that Predisposes Acute Myeloid Leukemia in Mice." Blood 104, no. 11 (November 16, 2004): 543. http://dx.doi.org/10.1182/blood.v104.11.543.543.
Full textHesse, Eric, Hiroaki Saito, Riku Kiviranta, Diego Correa, Kei Yamana, Lynn Neff, Daniel Toben, et al. "Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity." Journal of Cell Biology 191, no. 7 (December 20, 2010): 1271–83. http://dx.doi.org/10.1083/jcb.201009107.
Full textBushweller, John H., Stephen M. Lukasik, and Nancy A. Speck. "The CBFb-SMMHC Oncoprotein Inhibits Binding of the Runx1 Runt Domain to DNA." Blood 106, no. 11 (November 16, 2005): 2709. http://dx.doi.org/10.1182/blood.v106.11.2709.2709.
Full textTakarada, Takeshi. "Recent advances in Runx2 research." Folia Pharmacologica Japonica 144, no. 2 (2014): 98. http://dx.doi.org/10.1254/fpj.144.98.
Full textJeong, Jae-Hwan, Youn-Kwan Jung, Hyo-Jin Kim, Jung-Sook Jin, Hyun-Nam Kim, Sang-Min Kang, Shin-Yoon Kim, et al. "The Gene for Aromatase, a Rate-Limiting Enzyme for Local Estrogen Biosynthesis, Is a Downstream Target Gene of Runx2 in Skeletal Tissues." Molecular and Cellular Biology 30, no. 10 (March 15, 2010): 2365–75. http://dx.doi.org/10.1128/mcb.00672-09.
Full textLi, Na, Dongwei Luo, Xiaoxia Hu, Wei Luo, Guanghua Lei, Qian Wang, Ting Zhu, Junxia Gu, Yaojuan Lu, and Qiping Zheng. "RUNX2 and Osteosarcoma." Anti-Cancer Agents in Medicinal Chemistry 15, no. 7 (July 13, 2015): 881–87. http://dx.doi.org/10.2174/1871520615666150304151228.
Full textFujita, Takashi, Yasutaka Azuma, Ryo Fukuyama, Yuji Hattori, Carolina Yoshida, Masao Koida, Kiyokazu Ogita, and Toshihisa Komori. "Runx2 induces osteoblast and chondrocyte differentiation and enhances their migration by coupling with PI3K-Akt signaling." Journal of Cell Biology 166, no. 1 (June 28, 2004): 85–95. http://dx.doi.org/10.1083/jcb.200401138.
Full textShi, Xiuming, Vishwa Deepak, Linghui Wang, Xueqing Ba, Toshihisa Komori, Xianlu Zeng, and Wenguang Liu. "Thrombospondin-1 Is a Putative Target Gene of Runx2 and Runx3." International Journal of Molecular Sciences 14, no. 7 (July 10, 2013): 14321–32. http://dx.doi.org/10.3390/ijms140714321.
Full textZhang, He-Yu, Long Jin, Gail A. Stilling, Katharina H. Ruebel, Kendra Coonse, Yoshinori Tanizaki, Avraham Raz, and Ricardo V. Lloyd. "RUNX1 and RUNX2 upregulate Galectin-3 expression in human pituitary tumors." Endocrine 35, no. 1 (November 20, 2008): 101–11. http://dx.doi.org/10.1007/s12020-008-9129-z.
Full textSalingcarnboriboon, Ruchanee, Kunikazu Tsuji, Toshihisa Komori, Kazuhisa Nakashima, Yoichi Ezura, and Masaki Noda. "Runx2 Is a Target of Mechanical Unloading to Alter Osteoblastic Activity and Bone Formation in Vivo." Endocrinology 147, no. 5 (May 1, 2006): 2296–305. http://dx.doi.org/10.1210/en.2005-1020.
Full textMasuda, Tatsuya, Hirohito Kubota, Naoya Sakuramoto, Asuka Hada, Ayaka Horiuchi, Asami Sasaki, Kanako Takeda, et al. "RUNX-NFAT Axis As a Novel Therapeutic Target for AML and T Cell Immunity." Blood 136, Supplement 1 (November 5, 2020): 25–26. http://dx.doi.org/10.1182/blood-2020-143458.
Full textLi, Xueni, Mei Huang, Huiling Zheng, Yinyin Wang, Fangli Ren, Yu Shang, Yonggong Zhai, et al. "CHIP promotes Runx2 degradation and negatively regulates osteoblast differentiation." Journal of Cell Biology 181, no. 6 (June 9, 2008): 959–72. http://dx.doi.org/10.1083/jcb.200711044.
Full textMaillard, Ivan, Laleh Talebian, Zhe Li, Yalin Guo, Daisuke Sugiyama, Maren E. Speck, Warren S. Pear, and Nancy A. Speck. "A Hypomorphic Cbfb Allele Reveals a Critical Dosage-Sensitive Function of Core Binding Factors at the Earliest Stages of T Cell Development." Blood 106, no. 11 (November 16, 2005): 124. http://dx.doi.org/10.1182/blood.v106.11.124.124.
Full textJonason, J. H., G. Xiao, M. Zhang, L. Xing, and D. Chen. "Post-translational Regulation of Runx2 in Bone and Cartilage." Journal of Dental Research 88, no. 8 (August 2009): 693–703. http://dx.doi.org/10.1177/0022034509341629.
Full textZhang, You-you, Xi Li, Shu-wen Qian, Liang Guo, Hai-yan Huang, Qun He, Yuan Liu, Chun-gu Ma, and Qi-Qun Tang. "Down-Regulation of Type I Runx2 Mediated by Dexamethasone Is Required for 3T3-L1 Adipogenesis." Molecular Endocrinology 26, no. 5 (May 1, 2012): 798–808. http://dx.doi.org/10.1210/me.2011-1287.
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