Academic literature on the topic 'Runt related transcription factor'
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Journal articles on the topic "Runt related transcription factor"
Saikia, Snigdha, Asad Ur Rehman, Prajjalendra Barooah, Preeti Sarmah, Mallika Bhattacharyya, Muktanjalee Deka, Manab Deka, Bhabadev Goswami, Syed Akhtar Husain, and Subhash Medhi. "Alteration in the expression of MGMT and RUNX3 due to non-CpG promoter methylation and their correlation with different risk factors in esophageal cancer patients." Tumor Biology 39, no. 5 (May 2017): 101042831770163. http://dx.doi.org/10.1177/1010428317701630.
Full textYu, Shibing, Yu Jiang, Deborah L. Galson, Min Luo, Yumei Lai, Yi Lu, Hong-Jiao Ouyang, Jian Zhang, and Guozhi Xiao. "General Transcription Factor IIA-γ Increases Osteoblast-specificOsteocalcinGene Expression via Activating Transcription Factor 4 and Runt-related Transcription Factor 2." Journal of Biological Chemistry 283, no. 9 (January 2, 2008): 5542–53. http://dx.doi.org/10.1074/jbc.m705653200.
Full textThirunavukkarasu, Kannan, Muktar Mahajan, Keith W. McLarren, Stefano Stifani, and Gerard Karsenty. "Two Domains Unique to Osteoblast-Specific Transcription Factor Osf2/Cbfa1 Contribute to Its Transactivation Function and Its Inability To Heterodimerize with Cbfβ." Molecular and Cellular Biology 18, no. 7 (July 1, 1998): 4197–208. http://dx.doi.org/10.1128/mcb.18.7.4197.
Full textColler, Hilary A. "The Runt-related transcription factor 1 in prostate cancer-associated fibroblasts." Proceedings of the National Academy of Sciences 111, no. 46 (November 10, 2014): 16238–39. http://dx.doi.org/10.1073/pnas.1418976111.
Full textBoström, Kristina I. "DNA Damage Response, Runx2 (Runt-Related Transcription Factor 2), and Vascular Calcification." Arteriosclerosis, Thrombosis, and Vascular Biology 41, no. 4 (April 2021): 1358–59. http://dx.doi.org/10.1161/atvbaha.121.315836.
Full textChi, Xin-Zi, Jiyeon Kim, Yong-Hee Lee, Jung-Won Lee, Kyeong-Sook Lee, Heejun Wee, Wun-Jae Kim, et al. "Runt-Related Transcription Factor RUNX3 Is a Target of MDM2-Mediated Ubiquitination." Cancer Research 69, no. 20 (October 6, 2009): 8111–19. http://dx.doi.org/10.1158/0008-5472.can-09-1057.
Full textHuang, Shu-Pin, Yu-Hsuan Lan, Te-Ling Lu, Jiunn-Bey Pao, Ta-Yuan Chang, Hong-Zin Lee, Wen-Hui Yang, et al. "Clinical significance of runt-related transcription factor 1 polymorphism in prostate cancer." BJU International 107, no. 3 (August 24, 2010): 486–92. http://dx.doi.org/10.1111/j.1464-410x.2010.09512.x.
Full textDU, FEIYA, HUILING WU, ZHIQIN ZHOU, and YU LIU. "microRNA-375 inhibits osteogenic differentiation by targeting runt-related transcription factor 2." Experimental and Therapeutic Medicine 10, no. 1 (May 7, 2015): 207–12. http://dx.doi.org/10.3892/etm.2015.2477.
Full textTanaka, Shigetomi, Hidenori Shiraha, Yutaka Nakanishi, Shin-Ichi Nishina, Minoru Matsubara, Shigeru Horiguchi, Nobuyuki Takaoka, et al. "Runt-related transcription factor 3 reverses epithelial-mesenchymal transition in hepatocellular carcinoma." International Journal of Cancer 131, no. 11 (April 24, 2012): 2537–46. http://dx.doi.org/10.1002/ijc.27575.
Full textGil-Yarom, Naama, Lihi Radomir, Lital Sever, Matthias P. Kramer, Hadas Lewinsky, Chamutal Bornstein, Ronnie Blecher-Gonen, et al. "CD74 is a novel transcription regulator." Proceedings of the National Academy of Sciences 114, no. 3 (December 28, 2016): 562–67. http://dx.doi.org/10.1073/pnas.1612195114.
Full textDissertations / Theses on the topic "Runt related transcription factor"
Mümmler, Carlo [Verfasser], and Melanie [Akademischer Betreuer] Königshoff. "Runt-related transcription factor 2 in pulmonary fibrosis / Carlo Mümmler ; Betreuer: Melanie Königshoff." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2019. http://d-nb.info/1180285786/34.
Full textCuringa, Gabrielle Mercedes. "The role of runt-related transcription factor 2 in arterial smooth muscle cell mineralization /." Thesis, Connect to this title online; UW restricted, 2003. http://hdl.handle.net/1773/6353.
Full textIsehaq, Saif Said Al-Huseini. "Deletion of IκB-Kinase β in Smooth Muscle Cells Induces Vascular Calcification Through β-Catenin-Runt-Related Transcription Factor 2 Signaling." Kyoto University, 2018. http://hdl.handle.net/2433/232306.
Full textAlsabeelah, Nimer Fehaid N. "Vascular calcification in rat cultured smooth muscle cells : a role for nitric oxide." Thesis, University of Hertfordshire, 2016. http://hdl.handle.net/2299/17217.
Full textVaughan, Tanya, and n/a. "Identifying Genes Influencing Bone Mineral Density." Griffith University. School of Health Science, 2004. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20040430.161453.
Full textVaughan, Tanya. "Identifying Genes Influencing Bone Mineral Density." Thesis, Griffith University, 2004. http://hdl.handle.net/10072/366470.
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Doctor of Philosophy (PhD)
School of Health Sciences
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Taber, Thomas Howland. "Thyroid Hormone Receptor SS (trß) Regulation Of Runt-Related Transcription Factor 2 (runx2) In Thyroid Tumorigenesis: Determination Of The Trß Nuclear Protein Complexes That Associate With The Runx2 Gene." ScholarWorks @ UVM, 2017. http://scholarworks.uvm.edu/graddis/820.
Full textCardoso, Camila Lopes. "Análise morfométrica e molecular da alveolite induzida em ratos com diferentes modalidades de tratamento." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/25/25132/tde-27052009-102252/.
Full textDry socket is an inflammatory postoperative complication that undertakes sockets of recently extracted teeth. The incidence of such complication varies from 1 to 4% and might reach up to 30%. The objective of this study was to analyze the biological mechanisms involved in the repair process of intentionally infected sockets in mice; compare different treatment conditions and correlate the results of two different analysis (microscopic and molecular). 84 mice were used in this study, divided according the following groups: I: uninfected socket; II: infected socket without any treatment; III: infected socket treated with irrigation of 2% sodium iodide and 3% hydrogen peroxide solution at 1:1 proportion; and IV: infected socket submitted to curettage, physiological saline solution irrigation and fulfillment with metronidazole base paste. The animals were killed at a postoperative period of 6, 15 and 28 days. A quantitative analysis was performed using a RealTimePCR to evaluate the genes expression involved [Collagen Type I (COL-I), vascular endothelial growth factor (VEGF), osteocalcin (OCN), alkaline phosphatase (ALP), runt-related transcription factor 2 (RUNX2) and tumor necrosis factor-alpha (TNF-\'alpha\')], in the repair process, correlating its expression with the microscopic characteristics observed in both qualitative and quantitative manner. Based in the results of the microscopic and molecular analysis, it can be concluded that the RUNX2, OCN and TNF-\'alpha\' markers can be used as indicators to evaluate the dry socket bone neoformation and inflammatory infiltrate quantity. The ALP and VEGF markers did not represented appropriately what was observed microscopically. Although the dry socket treatment with metronidazole base paste promotes an increase in the bone neoformation density at 28 days, no difference was found among the treatments.
Bäckström, Stefan. "The hematopoietic transcription factor RUNX1 : a structural view." Doctoral thesis, Umeå University, Umeå Centre for Molecular Pathogenesis (UCMP), 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-192.
Full textThe malfunction of the transcriptional regulator RUNX1 is the major cause of several variants of acute human leukemias and its normal function is to regulate the development of the blood system in concert with other transcriptional co-regulators. RUNX1 belongs to a conserved family of heterodimeric transcription factors that share a conserved DNA binding domain, the Runt domain (RD), named after the first member of this group – Runt - found in Drosophila melanogaster. The binding partner CBFβ serves as a regulator of RUNX by enhancing its DNA binding affinity through an allosteric mechanism.
The main focus ofo my thesis work has been the crystallization and structural analysis of the RUNX1 RD and involved also more technical methodological aspects that can be applied to X-ray crystallography in general.
The high resolution crystal structure of the free RD shows that this immunoglobulin-like molecule undergoes significant structural changes upon binding to both CBFβ and DNA. This involves a large flip of the L11 loop from a closed conformation in the free protein to an open conformation when CBFβ and/or DNA are bound. We refer to this transition as the “S-switch”. Smaller but significant conformational changes in other parts of the RD accompany the “S-switch”. We suggest that CBFβ triggers and stabilizes the “S-switch” which leads to the conversion of the RD into a conformation enhanced for DNA binding.
During the structural analysis of the RD we identified two chloride ions that are coordinated by residues otherwise involved in DNA binding. In electrophoretic mobility-shift analyses (EMSA) we demonstrated a chloride ion concentration dependent stimulation of the DNA binding affinity of RUNX1. We further showed by NMR line width broadening experiments that the chloride binding occurred within the physiological range. A comparable DNA binding stimulation of RUNX1 was seen in the presence of negative amino acids. This suggests a regulation of the DNA binding activity of RUNX1 proteins through acidic amino acid residues possibly provided by activation domains of transcriptional co-regulators that interact with RUNX1.
The use of the anomalous signal from halide ions has become a powerful technique for obtaining phase information. By replacing the sodium chloride with potassium bromide in the crystallisation conditions of the RD, we could demonstrate in a single wavelength anomalous diffraction (SAD) experiment that the anomalous signal from 2 bromide ions were sufficient to phase a 16 kDa protein. Due to lack of completeness in the low-resolution shells caused by overloaded intensities, density modification schemes failed and the resulting electron density maps were not interpretable. By combining the highresolution
synchrotron data with low-resolution data from a native data set collected on a home X-ray source, the density modified bromide phases gave easily traceable maps.
Yu, Wai Man C. Y. O. L. "Targeting the Myocardin-related transcription factor/serum response factor (MRTF/SRF) pathway in conjunctival fibrosis." Thesis, University College London (University of London), 2017. http://discovery.ucl.ac.uk/1559574/.
Full textBooks on the topic "Runt related transcription factor"
Soliman, Karam F. A., and Yashwant Pathak. Flavonoids and Anti-Aging: The Role of Transcription Factor Nuclear Erythroid 2-Related Factor2. Taylor & Francis Group, 2023.
Find full textSoliman, Karam F. A., and Yashwant Pathak. Flavonoids and Anti-Aging: The Role of Transcription Factor Nuclear Erythroid 2-Related Factor2. Taylor & Francis Group, 2023.
Find full textSoliman, Karam F. A., and Yashwant Pathak. Flavonoids and Anti-Aging: The Role of Transcription Factor Nuclear Erythroid 2-Related Factor2. Taylor & Francis Group, 2023.
Find full textStructure-function analysis of the immediate early transcription factor Egr-1 and identification of a gene repressed by a related zinc finger protein, the Wilms tumor suppressor WT1. 1992.
Find full textChess, Andrew, and Schahram Akbarian. The Human Brain and its Epigenomes. Edited by Dennis S. Charney, Eric J. Nestler, Pamela Sklar, and Joseph D. Buxbaum. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190681425.003.0003.
Full textBook chapters on the topic "Runt related transcription factor"
Will, Thorsten. "Related work." In Predicting Transcription Factor Complexes, 25–43. Wiesbaden: Springer Fachmedien Wiesbaden, 2014. http://dx.doi.org/10.1007/978-3-658-08269-7_2.
Full textIkeda, Kazuhiro, Kuniko Horie-Inoue, and Satoshi Inoue. "Analysis of TFRNs Associated with Steroid Hormone-Related Cancers." In Transcription Factor Regulatory Networks, 197–209. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-0805-9_16.
Full textIto, Yoshiaki, and Suk-Chul Bae. "The Runt Domain Transcription Factor, PEBP2/CBF, and its Involvement in Human Leukemia." In Oncogenes as Transcriptional Regulators, 107–32. Basel: Birkhäuser Basel, 1997. http://dx.doi.org/10.1007/978-3-0348-8934-6_4.
Full textGrant, Struan F. A., and Leif Groop. "Transcription Factor 7-Like 2 (TCF7L2)." In The Genetics of Type 2 Diabetes and Related Traits, 297–316. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-01574-3_14.
Full textLambros, Mandy L., and Scott M. Plafker. "Oxidative Stress and the Nrf2 Anti-Oxidant Transcription Factor in Age-Related Macular Degeneration." In Retinal Degenerative Diseases, 67–72. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-17121-0_10.
Full textGilmore, Thomas D., and Céline Gélinas. "Methods for Assessing the In Vitro Transforming Activity of NF-κB Transcription Factor c-Rel and Related Proteins." In Methods in Molecular Biology, 427–46. New York, NY: Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2422-6_26.
Full text"Runt-Related Transcription Factor 3." In Encyclopedia of Signaling Molecules, 4773. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_103376.
Full textPanovska-Stavridis, Irina. "Molecular Monitoring in Acute Myeloid Leukemia Patients Undergoing Matched Unrelated Donor: Hematopoietic Stem Cell Transplantation." In Acute Leukemias [Working Title]. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.94830.
Full textTarı Selçuk, Kevser. "Epidemiology of Inflammation-Related Diseases." In Role of Nutrition in Providing Pro-/Anti-Inflammatory Balance, 24–44. IGI Global, 2020. http://dx.doi.org/10.4018/978-1-7998-3594-3.ch002.
Full textIsomura, Hiroki. "DNA Polymerase Processivity Factor of Human Cytomegalovirus May Be a Key Molecule for Molecular Coupling of Viral DNA Replication to Transcription." In DNA Replication and Related Cellular Processes. InTech, 2011. http://dx.doi.org/10.5772/18144.
Full textConference papers on the topic "Runt related transcription factor"
Liu, Ka, Richard L. Smith, Trang Nguyen-Vu, Nicholes R. Candelaria, Colin M. Rogerson, W. Evan Johnson, Edwin Cheung, et al. "Abstract 3107: Runt-related transcription factor 1 (RUNX1) is involved in transcriptional repression by estrogen receptor and breast cancer cell proliferation." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-3107.
Full textRada, Miran, Audrey Kapelanski-Lamoureux, Stephanie Petrillo, Sébastien Tabariès, Peter Siegel, Anthoula Lazaris, and Peter Metrakos. "Abstract 3935: Runt related transcription factor-1 (runx1) plays a central role in vessel co-option of colorectal cancer liver metastases." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-3935.
Full textLestari, Citra, Eryati Darwin, Deddi Prima Putra, and Netti Suharti. "The Effect of α-Mangosteen on Runt-Related Transcription Factor 2 and Tartrate-Resistant Acid Phosphatase 5b Expressions on Bone Remodeling in Periodontitis (An Experimental Research on Wistar Rats)." In 1st International Conference on Health Sciences and Biotechnology (ICHB 2021). Paris, France: Atlantis Press, 2022. http://dx.doi.org/10.2991/ahsr.k.220303.007.
Full textHuang, Xiangwei, Ying Gai, Rajesh Thouta, Naiheng Yang, Miao Mi, Victor Thannickal, and Yong Zhou. "Mechanotransduction-Induced Myofibroblast Differentiation And Survival Is Mediated By Myocardin-Related Transcription Factor (MRTF)-A." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a3569.
Full textArima, Yoshimi, Mari Hosonaga, and Hideyuki Saya. "Abstract 522: The epithelial-mesenchymal transition-related transcription factor ZEB suppressesClaudinexpression in breast cancer cells." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-522.
Full textHasegawa, Reika. "A homeodomain transcription factor, BRASSISTEORID-RELATED HOMEOBOX 1, act as a negative regulator for Brassisteroid feedback loop." In ASPB PLANT BIOLOGY 2020. USA: ASPB, 2020. http://dx.doi.org/10.46678/pb.20.1052915.
Full textHuang, Xiangwei, Naiheng Yang, Vincent F. Fiore, Thomas Barker, Yi Sun, Stephan W. Morris, Victor J. Thannickal, and Yong Zhou. "Matrix Stiffness-Induced Myofibroblast Differentiation Is Regulated By Actin Dynamics And Myocardin-Related Transcription Factor (MRTF)-A-Mediated Intrinsic Mechanotransduction." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a1032.
Full textHomps-Legrand, M., M. Jaillet, L. Deneuville, B. Crestani, and A. Mailleux. "Lineage Tracing of Cells Expressing the Mesenchymal Profibrotic Transcription Factor Prrx1 (Paired Related Homeobox Protein 1) in Normal and Fibrotic Lung." In American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5231.
Full textLi, Mingzhe, Zhenyu Wang, Zhongyi Xie, Jing Luo, Dongsun Cao, and Tongcun Zhang. "CREB-binding Protein (CBP) p300 Enhanced the Expression of Cardiac Hypertrophy-Specific Genes Activated by Myocardin-Related Transcription Factor-A (MRTF-A)." In 2012 International Conference on Biomedical Engineering and Biotechnology (iCBEB). IEEE, 2012. http://dx.doi.org/10.1109/icbeb.2012.118.
Full textShikata, Tetsuo, Toshihiko Shiraishi, Shin Morishita, and Ryohei Takeuchi. "Effects of Acceleration Amplitude and Frequency of Mechanical Vibration on Cultured Osteoblasts." In ASME 2008 International Mechanical Engineering Congress and Exposition. ASMEDC, 2008. http://dx.doi.org/10.1115/imece2008-67221.
Full textReports on the topic "Runt related transcription factor"
Funkenstein, Bruria, and Shaojun (Jim) Du. Interactions Between the GH-IGF axis and Myostatin in Regulating Muscle Growth in Sparus aurata. United States Department of Agriculture, March 2009. http://dx.doi.org/10.32747/2009.7696530.bard.
Full textGrumet, Rebecca, Rafael Perl-Treves, and Jack Staub. Ethylene Mediated Regulation of Cucumis Reproduction - from Sex Expression to Fruit Set. United States Department of Agriculture, February 2010. http://dx.doi.org/10.32747/2010.7696533.bard.
Full textCasey, Therese, Sameer J. Mabjeesh, Avi Shamay, and Karen Plaut. Photoperiod effects on milk production in goats: Are they mediated by the molecular clock in the mammary gland? United States Department of Agriculture, January 2014. http://dx.doi.org/10.32747/2014.7598164.bard.
Full textCrisosto, Carlos, Susan Lurie, Haya Friedman, Ebenezer Ogundiwin, Cameron Peace, and George Manganaris. Biological Systems Approach to Developing Mealiness-free Peach and Nectarine Fruit. United States Department of Agriculture, 2007. http://dx.doi.org/10.32747/2007.7592650.bard.
Full textHorwitz, Benjamin, and Barbara Gillian Turgeon. Secondary Metabolites, Stress, and Signaling: Roles and Regulation of Peptides Produced by Non-ribosomal Peptide Synthetases. United States Department of Agriculture, 2005. http://dx.doi.org/10.32747/2005.7696522.bard.
Full textHorwitz, Benjamin A., and Barbara Gillian Turgeon. Fungal Iron Acquisition, Oxidative Stress and Virulence in the Cochliobolus-maize Interaction. United States Department of Agriculture, March 2012. http://dx.doi.org/10.32747/2012.7709885.bard.
Full textLers, Amnon, and Gan Susheng. Study of the regulatory mechanism involved in dark-induced Postharvest leaf senescence. United States Department of Agriculture, January 2009. http://dx.doi.org/10.32747/2009.7591734.bard.
Full textChen, Junping, Zach Adam, and Arie Admon. The Role of FtsH11 Protease in Chloroplast Biogenesis and Maintenance at Elevated Temperatures in Model and Crop Plants. United States Department of Agriculture, May 2013. http://dx.doi.org/10.32747/2013.7699845.bard.
Full textApplebaum, Shalom W., Lawrence I. Gilbert, and Daniel Segal. Biochemical and Molecular Analysis of Juvenile Hormone Synthesis and its Regulation in the Mediterranean Fruit Fly (Ceratitis capitata). United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7570564.bard.
Full textFriedman, Haya, Julia Vrebalov, James Giovannoni, and Edna Pesis. Unravelling the Mode of Action of Ripening-Specific MADS-box Genes for Development of Tools to Improve Banana Fruit Shelf-life and Quality. United States Department of Agriculture, January 2010. http://dx.doi.org/10.32747/2010.7592116.bard.
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